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FORT LAUDERDALE, Fla. (AP) — A boat explosion at a South Florida marina has left one person dead and five others injured, officials said. The explosion occurred Monday night at the Lauderdale Marina, Fort Lauderdale Fire Rescue said in a social media post. Rescue workers transported five people to local hospitals, three with traumatic injuries, officials said. A sixth person was found dead in the water several hours later by the Broward Sheriff's Office. Fire rescue officials said they didn't immediately know what caused the explosion.THOUSAND OAKS, Calif. , Dec. 2, 2024 /PRNewswire/ -- Amgen (NASDAQ:AMGN) will present at Citi's 2024 Global Healthcare Conference at 9:30 a.m. ET on Thursday , Dec. 5, 2024. Peter Griffith , executive vice president and chief financial officer at Amgen, Jay Bradner , executive vice president of Research and Development and chief scientific officer at Amgen, and Susan Sweeney , executive vice president of Obesity and Related Conditions at Amgen, will participate in a fireside chat at the conference. The webcast will be broadcast over the internet simultaneously and will be available to members of the news media, investors and the general public. The webcast, as with other selected presentations regarding developments in Amgen's business given by management at certain investor and medical conferences, can be found on Amgen's website, www.amgen.com , under Investors. Information regarding presentation times, webcast availability and webcast links are noted on Amgen's Investor Relations Events Calendar. The webcast will be archived and available for replay for at least 90 days after the event. About Amgen Amgen discovers, develops, manufactures and delivers innovative medicines to help millions of patients in their fight against some of the world's toughest diseases. More than 40 years ago, Amgen helped to establish the biotechnology industry and remains on the cutting-edge of innovation, using technology and human genetic data to push beyond what's known today. Amgen is advancing a broad and deep pipeline that builds on its existing portfolio of medicines to treat cancer, heart disease, osteoporosis, inflammatory diseases and rare diseases. In 2024, Amgen was named one of the "World's Most Innovative Companies" by Fast Company and one of "America's Best Large Employers" by Forbes, among other external recognitions . Amgen is one of the 30 companies that comprise the Dow Jones Industrial Average ® , and it is also part of the Nasdaq-100 Index ® , which includes the largest and most innovative non-financial companies listed on the Nasdaq Stock Market based on market capitalization. Amgen is one of the 30 companies that comprise the Dow Jones Industrial Average and is also part of the Nasdaq-100 index. In 2023, Amgen was named one of "America's Greatest Workplaces" by Newsweek, one of "America's Climate Leaders" by USA Today and one of the "World's Best Companies" by TIME. For more information, visit Amgen.com and follow us on X (formerly known as Twitter), LinkedIn , Instagram , TikTok , YouTube and Threads . Amgen Forward-Looking Statements This news release contains forward-looking statements that are based on the current expectations and beliefs of Amgen. All statements, other than statements of historical fact, are statements that could be deemed forward-looking statements, including any statements on the outcome, benefits and synergies of collaborations, or potential collaborations, with any other company (including BeiGene, Ltd. or Kyowa Kirin Co., Ltd.), the performance of Otezla ® (apremilast) (including anticipated Otezla sales growth and the timing of non-GAAP EPS accretion), our acquisitions of Teneobio, Inc., ChemoCentryx, Inc., or Horizon Therapeutics plc (including the prospective performance and outlook of Horizon's business, performance and opportunities, any potential strategic benefits, synergies or opportunities expected as a result of such acquisition, and any projected impacts from the Horizon acquisition on our acquisition-related expenses going forward), as well as estimates of revenues, operating margins, capital expenditures, cash, other financial metrics, expected legal, arbitration, political, regulatory or clinical results or practices, customer and prescriber patterns or practices, reimbursement activities and outcomes, effects of pandemics or other widespread health problems on our business, outcomes, progress, and other such estimates and results. Forward-looking statements involve significant risks and uncertainties, including those discussed below and more fully described in the Securities and Exchange Commission reports filed by Amgen, including our most recent annual report on Form 10-K and any subsequent periodic reports on Form 10-Q and current reports on Form 8-K. Unless otherwise noted, Amgen is providing this information as of the date of this news release and does not undertake any obligation to update any forward-looking statements contained in this document as a result of new information, future events or otherwise. No forward-looking statement can be guaranteed and actual results may differ materially from those we project. Our results may be affected by our ability to successfully market both new and existing products domestically and internationally, clinical and regulatory developments involving current and future products, sales growth of recently launched products, competition from other products including biosimilars, difficulties or delays in manufacturing our products and global economic conditions. In addition, sales of our products are affected by pricing pressure, political and public scrutiny and reimbursement policies imposed by third-party payers, including governments, private insurance plans and managed care providers and may be affected by regulatory, clinical and guideline developments and domestic and international trends toward managed care and healthcare cost containment. Furthermore, our research, testing, pricing, marketing and other operations are subject to extensive regulation by domestic and foreign government regulatory authorities. We or others could identify safety, side effects or manufacturing problems with our products, including our devices, after they are on the market. Our business may be impacted by government investigations, litigation and product liability claims. In addition, our business may be impacted by the adoption of new tax legislation or exposure to additional tax liabilities. If we fail to meet the compliance obligations in the corporate integrity agreement between us and the U.S. government, we could become subject to significant sanctions. Further, while we routinely obtain patents for our products and technology, the protection offered by our patents and patent applications may be challenged, invalidated or circumvented by our competitors, or we may fail to prevail in present and future intellectual property litigation. We perform a substantial amount of our commercial manufacturing activities at a few key facilities, including in Puerto Rico , and also depend on third parties for a portion of our manufacturing activities, and limits on supply may constrain sales of certain of our current products and product candidate development. An outbreak of disease or similar public health threat, such as COVID-19, and the public and governmental effort to mitigate against the spread of such disease, could have a significant adverse effect on the supply of materials for our manufacturing activities, the distribution of our products, the commercialization of our product candidates, and our clinical trial operations, and any such events may have a material adverse effect on our product development, product sales, business and results of operations. We rely on collaborations with third parties for the development of some of our product candidates and for the commercialization and sales of some of our commercial products. In addition, we compete with other companies with respect to many of our marketed products as well as for the discovery and development of new products. Discovery or identification of new product candidates or development of new indications for existing products cannot be guaranteed and movement from concept to product is uncertain; consequently, there can be no guarantee that any particular product candidate or development of a new indication for an existing product will be successful and become a commercial product. Further, some raw materials, medical devices and component parts for our products are supplied by sole third-party suppliers. Certain of our distributors, customers and payers have substantial purchasing leverage in their dealings with us. The discovery of significant problems with a product similar to one of our products that implicate an entire class of products could have a material adverse effect on sales of the affected products and on our business and results of operations. Our efforts to collaborate with or acquire other companies, products or technology, and to integrate the operations of companies or to support the products or technology we have acquired, may not be successful. There can be no guarantee that we will be able to realize any of the strategic benefits, synergies or opportunities arising from the Horizon acquisition, and such benefits, synergies or opportunities may take longer to realize than expected. We may not be able to successfully integrate Horizon, and such integration may take longer, be more difficult or cost more than expected. A breakdown, cyberattack or information security breach of our information technology systems could compromise the confidentiality, integrity and availability of our systems and our data. Our stock price is volatile and may be affected by a number of events. Our business and operations may be negatively affected by the failure, or perceived failure, of achieving our environmental, social and governance objectives. The effects of global climate change and related natural disasters could negatively affect our business and operations. Global economic conditions may magnify certain risks that affect our business. Our business performance could affect or limit the ability of our Board of Directors to declare a dividend or our ability to pay a dividend or repurchase our common stock. We may not be able to access the capital and credit markets on terms that are favorable to us, or at all. CONTACT: Amgen, Thousand Oaks Elissa Snook , 609-251-1407 (media) Justin Claeys , 805-313-9775 (investors) View original content to download multimedia: https://www.prnewswire.com/news-releases/amgen-to-present-at-citis-2024-global-healthcare-conference-302319891.html SOURCE AmgenComment - Videos of children opening boxes of toys and playing with them have become a feature of online marketing - making stars out of children as young as two. Twelve-year-old influencer Ryan Kaji, for example, earns US$30 million (NZ$53m) a year on YouTube leading one of the most popular children's channels. His empire was built on toy unboxing. An influencer (child or adult) with more than one million followers can earn upwards of $20,000 for one sponsored post, while a person with under 100,000 followers on a social media platform may still earn as much as $4000 for each sponsored post. But the rise of kidfluencers around the globe raises questions about the blurred lines between play and labour, independence and control, privacy, profit and online success. Our research examines these questions. By analysing existing research to clearly identify the challenges faced by child toy unboxers, we can guide future researchers and governments to best support children who are living parts of their lives online. YouTube as a career goal A 2023 global survey of children aged between eight and 12 found they were three times more likely to aspire to be a YouTuber (29 percent) than an astronaut (11 percent). Advertisers have taken note. Social media platforms Facebook, Instagram, Snapchat, TikTok, X (formerly Twitter) and YouTube collectively earned nearly $11 billion in advertising revenue in 2022 from United States-based users younger than 18. Toy unboxing has emerged as particularly popular, generating massive revenue and global audiences. These types of videos involved children who unbox, play and review toys. Unboxing videos became popular in the 2010s, with content creators unpacking products such as tech gadgets and fashion items. Toy unboxing is now one of the highest-earning genres on YouTube. Work, play or somewhere in between At first glance, unboxing videos seem to follow a simple entertainer-audience relationship. The kidfluencers emotionally engage with young viewers, who are then inspired to create their own toy wish lists. But behind the fun is a world of complexity often not obvious for young viewers (and sometimes older viewers too). These children are hired by companies - and managed by their parents - to promote toys and other products in an job-like arrangement. This has raised concerns about child exploitation, privacy risks and unethical work practices. But current child labour laws in New Zealand and elsewhere do not see child influencers as a type of "child worker". And it is difficult to do so. While kidfluencers seem to be genuinely playing with the sponsored toy, their content is managed by contracts with advertisers, and expectations set by their parents. Therefore it can't fully be labelled as "play". At the same time, calling these practices purely "labour" ignores the real excitement children feel when creating sponsored content. In 2020, the French government labelled kidfluencers a "grey zone" - where the child is not officially working, but nevertheless spends a significant amount of time making videos, or derives a significant level of income from them. Protecting children Another complexity is that some social media platforms require users to be over 13, yet some kidfluencers are toddlers, with parents creating and managing their accounts, including producing and posting their children's online content. While parents play a big role in managing their child's online presence, the child drives the toy sales, creating tension between parental control and a child's independence. And behind this all is the issue of money. A child's involvement - and success - is driven by the wants and needs of advertisers. This raises questions about how much of a say the child really has in terms of creating content. Privacy and online safety are two key issues facing the kidfluencer industry. The more content a child toy unboxer posts online, the more popular and profitable they can become. But at the same time, popularity brings very real risks. Young female unboxers - and female kidfluencers in general - have been targeted by online predators. To stay safe, some kidfluencers use fake names and don't share their location. But these strategies are not perfect. Current (and proposed) policies rarely balance protecting child stars with supporting their success in sponsored content. In recent years, however, France and individual states in the US have created laws to protect the kidfluencers' earnings. All governments should follow suit and create policies that recognise the challenges of the kidfluencer industry, and which support and protect the children involved. - This story was originally published on The Conversation Sign up for Ngā Pitopito Kōrero, a daily newsletter curated by our editors and delivered straight to your inbox every weekday.
TOPEKA, Kan. (AP) — Republicans made claims about illegal voting by noncitizens a centerpiece of their 2024 campaign messaging and plan to push legislation in the new Congress requiring voters to provide proof of U.S. citizenship. Yet there’s one place with a GOP supermajority where linking voting to citizenship appears to be a nonstarter: Kansas. That’s because the state has been there, done that, and all but a few Republicans would prefer not to go there again. Kansas imposed a proof-of-citizenship requirement over a decade ago that grew into one of the biggest political fiascos in the state in recent memory. The law, passed by the state Legislature in 2011 and implemented two years later, ended up blocking the voter registrations of more than 31,000 U.S. citizens who were otherwise eligible to vote. That was 12% of everyone seeking to register in Kansas for the first time. Federal courts ultimately declared the law an unconstitutional burden on voting rights, and it hasn’t been enforced since 2018. Kansas provides a cautionary tale about how pursuing an election concern that in fact is extremely rare risks disenfranchising a far greater number of people who are legally entitled to vote. The state’s top elections official, Secretary of State Scott Schwab, championed the idea as a legislator and now says states and the federal government shouldn’t touch it. “Kansas did that 10 years ago,” said Schwab, a Republican. “It didn’t work out so well.” Steven Fish, a 45-year-old warehouse worker in eastern Kansas, said he understands the motivation behind the law. In his thinking, the state was like a store owner who fears getting robbed and installs locks. But in 2014, after the birth of his now 11-year-old son inspired him to be “a little more responsible” and follow politics, he didn’t have an acceptable copy of his birth certificate to get registered to vote in Kansas. “The locks didn’t work,” said Fish, one of nine Kansas residents who sued the state over the law. “You caught a bunch of people who didn’t do anything wrong.” A small problem, but wide support for a fix Kansas’ experience appeared to receive little if any attention outside the state as Republicans elsewhere pursued proof-of-citizenship requirements this year. Arizona enacted a requirement this year, applying it to voting for state and local elections but not for Congress or president. The Republican-led U.S. House passed a proof-of-citizenship requirement in the summer and plans to bring back similar legislation after the GOP won control of the Senate in November. In Ohio, the Republican secretary of state revised the form that poll workers use for voter eligibility challenges to require those not born in the U.S. to show naturalization papers to cast a regular ballot. A federal judge declined to block the practice days before the election. Also, sizable majorities of voters in Iowa, Kentucky, Missouri, Oklahoma, South Carolina and the presidential swing states of North Carolina and Wisconsin were inspired to amend their state constitutions’ provisions on voting even though the changes were only symbolic. Provisions that previously declared that all U.S. citizens could vote now say that only U.S. citizens can vote — a meaningless distinction with no practical effect on who is eligible. To be clear, voters already must attest to being U.S. citizens when they register to vote and noncitizens can face fines, prison and deportation if they lie and are caught. “There is nothing unconstitutional about ensuring that only American citizens can vote in American elections,” U.S. Rep. Chip Roy, of Texas, the leading sponsor of the congressional proposal, said in an email statement to The Associated Press. Why the courts rejected the Kansas citizenship rule After Kansas residents challenged their state’s law, both a federal judge and federal appeals court concluded that it violated a law limiting states to collecting only the minimum information needed to determine whether someone is eligible to vote. That’s an issue Congress could resolve. The courts ruled that with “scant” evidence of an actual problem, Kansas couldn’t justify a law that kept hundreds of eligible citizens from registering for every noncitizen who was improperly registered. A federal judge concluded that the state’s evidence showed that only 39 noncitizens had registered to vote from 1999 through 2012 — an average of just three a year. In 2013, then-Kansas Secretary of State Kris Kobach, a Republican who had built a national reputation advocating tough immigration laws, described the possibility of voting by immigrants living in the U.S. illegally as a serious threat. He was elected attorney general in 2022 and still strongly backs the idea, arguing that federal court rulings in the Kansas case “almost certainly got it wrong.” Kobach also said a key issue in the legal challenge — people being unable to fix problems with their registrations within a 90-day window — has probably been solved. “The technological challenge of how quickly can you verify someone’s citizenship is getting easier,” Kobach said. “As time goes on, it will get even easier.” Would the Kansas law stand today? The U.S. Supreme Court refused to hear the Kansas case in 2020. But in August, it split 5-4 in allowing Arizona to continue enforcing its law for voting in state and local elections while a legal challenge goes forward. Seeing the possibility of a different Supreme Court decision in the future, U.S. Rep.-elect Derek Schmidt says states and Congress should pursue proof-of-citizenship requirements. Schmidt was the Kansas attorney general when his state’s law was challenged. “If the same matter arose now and was litigated, the facts would be different,” he said in an interview. But voting rights advocates dismiss the idea that a legal challenge would turn out differently. Mark Johnson, one of the attorneys who fought the Kansas law, said opponents now have a template for a successful court fight. “We know the people we can call,” Johnson said. “We know that we’ve got the expert witnesses. We know how to try things like this.” He predicted “a flurry — a landslide — of litigation against this.” Born in Illinois but unable to register in Kansas Initially, the Kansas requirement’s impacts seemed to fall most heavily on politically unaffiliated and young voters. As of fall 2013, 57% of the voters blocked from registering were unaffiliated and 40% were under 30. But Fish was in his mid-30s, and six of the nine residents who sued over the Kansas law were 35 or older. Three even produced citizenship documents and still didn’t get registered, according to court documents. “There wasn’t a single one of us that was actually an illegal or had misinterpreted or misrepresented any information or had done anything wrong,” Fish said. He was supposed to produce his birth certificate when he sought to register in 2014 while renewing his Kansas driver’s license at an office in a strip mall in Lawrence. A clerk wouldn’t accept the copy Fish had of his birth certificate. He still doesn’t know where to find the original, having been born on an Air Force base in Illinois that closed in the 1990s. Several of the people joining Fish in the lawsuit were veterans, all born in the U.S., and Fish said he was stunned that they could be prevented from registering. Liz Azore, a senior adviser to the nonpartisan Voting Rights Lab, said millions of Americans haven’t traveled outside the U.S. and don’t have passports that might act as proof of citizenship, or don’t have ready access to their birth certificates. She and other voting rights advocates are skeptical that there are administrative fixes that will make a proof-of-citizenship law run more smoothly today than it did in Kansas a decade ago. “It’s going to cover a lot of people from all walks of life,” Avore said. “It’s going to be disenfranchising large swaths of the country.” ___ Associated Press writer Julie Carr Smyth in Columbus, Ohio, contributed to this report.None
5 top tech gifts for the holidaysCowboys owner Jerry Jones sounds like he wants Christmas Day to become as synonymous with football as it is with Santa. Jones appeared on 105.3 The Fan on Tuesday and hinted that the NFL was in it for the long haul when it came to putting games on Christmas Day, no matter what day of the week the holiday falls on. “Christmas Day is Christmas Day, and it doesn’t wait around for what day it’s on. We want to be there on Christmas Day,” Jones said during the radio interview. “I would think the future is whatever day it’s on, we’re going to be there on Christmas.” Christmas Day falls on a Wednesday this season, and jamming the Chiefs, Steelers, Ravens and Texans in on an unusual day for NFL forced the league to have those teams play this past Saturday instead of Sunday. Next year Christmas is on Thursday, and the next potential headache would come in 2029, when Christmas will be on a Tuesday. The NFL has had a foothold on Christmas Day since 2020 and they will continue that this year when they play two games that are slated to air on streamer Netflix. The Chiefs and Steelers will play at 1 p.m. and the Ravens and Texans will face one another at 4:30 p.m., with the second game featuring a special halftime performance by Beyoncé. The holiday has traditionally been a date that the NBA has dominated as the only professional sports league in North America that is in action. The NHL shuts down for the holidays annually and the NFL had previously played when Christmas had fallen on a day traditionally that games would be scheduled on. The NBA has its normal allotment of five games on Christmas Day this year, the slate serving to highlight the league’s top teams and stars. Wednesday’s slate of NFL games will also be a monumental moment for the league as it will be the first time that its newest broadcast partner will carry games. Netflix had come under fire for the issues that its stream of the Jake Paul-Mike Tyson fight had .Young, Spartz, Banks get committee assignments
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