
ST. THOMAS, Virgin Islands (AP) — Javohn Garcia scored 16 points as McNeese beat Illinois State 76-68 on Friday. Garcia also contributed seven rebounds for the Cowboys (3-2). Brandon Murray shot 4 of 10 from the field and 5 for 7 from the line to add 13 points. Sincere Parker shot 4 for 8 (2 for 5 from 3-point range) and 3 of 4 from the free-throw line to finish with 13 points. Ty Pence led the way for the Redbirds (3-2) with 14 points and six rebounds. Malachi Poindexter added 13 points for Illinois State. Logan Wolf had 11 points. The Associated Press created this story using technology provided by Data Skrive and data from Sportradar .Zipalertinib is a small molecule commercialized by , with a leading Phase III program in Non-Small Cell Lung Cancer. According to Globaldata, it is involved in 3 clinical trials, which are ongoing. Smarter leaders trust GlobalData The gold standard of business intelligence. The revenue for Zipalertinib is expected to reach an annual total of $47 mn by 2037 in the US based off GlobalData’s Expiry Model. The drug’s revenue forecasts along with estimated costs are used to measure the value of an investment opportunity in that drug, otherwise known as net present value (NPV). Applying the drug’s phase transition success rate to remaining R&D costs and likelihood of approval (LoA) to sales related costs provides a risk-adjusted NPV model (rNPV). The rNPV model is a more conservative valuation measure that accounts for the risk of a drug in clinical development failing to progress. Zipalertinib Overview zipalertinib is under development for the treatment of non-small cell lung cancer. The drug candidate acts by targeting epidermal growth factor receptor (EGFR) with Exon 20 insertions. It is administered as a tablet through oral route. Otsuka Overview is a holding company, which operates various businesses such as pharmaceuticals, nutraceuticals, consumer products, and other businesses through its subsidiaries. It focuses on the research and development, manufacture, and sale of medicines for the treatment of cancer, cardiovascular diseases, central nervous system disorders, ophthalmic diseases, gastrointestinal and respiratory diseases, infectious diseases, dermatological conditions, and allergies. The company’s product portfolio includes pharmaceutical products, cosmedics, functional foods and beverages, fine chemicals, electronic equipment, functional chemicals, medical devices, and OTC products. The company markets its products across North America, Europe, and Asia. is headquartered in Minato-ku, Tokyo, Japan. The company reported revenues of (Yen) JPY2,018,568 million for the fiscal year ended December 2023 (FY2023), an increase of 16.1% over FY2022. In FY2023, the company’s operating margin was 6.9%, compared to an operating margin of 8.8% in FY2022. In FY2023, the company recorded a net margin of 6%, compared to a net margin of 7.7% in FY2022. The company reported revenues of JPY589,412 million for the second quarter ended June 2024, an increase of 13.5% over the previous quarter. For a complete picture of Zipalertinib’s valuation, From Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors. , the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article. To create this model, GlobalData takes into account factors including patent law, known and projected regulatory approval processes, cash flows, drug margins and company expenses. Combining these data points with GlobalData’s world class analysis creates high value models that companies can use to help in evaluation processes for each drug or company. The rNPV method integrates the probability of a drug reaching a clinical stage into the cash flow at that time, which provides a more accurate valuation, as it considers the probability that the drug never makes it through the clinical pathway to commercialization. GlobalData’s rNPV model uses proprietary likelihood of approval (LoA) and phase transition success rate (PTSR) data for the indication in the highest development stage, which can be found on GlobalData’s .
The holiday season is upon us, and what better way to celebrate than by gifting the latest and greatest in tech toys? Whether you're shopping for a tech-savvy teen, a gadget-loving friend, or even a young aspiring engineer, there’s a world of innovative toys to spark creativity, fun, and learning. In this round-up, we’ve curated some of the best Christmas tech toys that are sure to delight and inspire... GoChess Mini Price: £199.99 An AI-powered smart chess board with colour-coded coaching lights, and online connectivity through the dedicated app. GoChess Mini isn't just about playing the game; it's about improving skills, tracking progress, and connecting with other players. Offering three play modes, users can play GoChess Mini face-to-face with an opponent or alone in AI mode (with 32 levels of difficulty to choose from). Additionally, they can connect to popular chess platforms (Lichess and Chess.com) and play against people around the world or solve challenging puzzles and revisit historical games. Maxcom Kiddo Smartwatch RRP: £69.99 The 4G Kiddo smartwatch is designed for children while also offering additional safety features, including location tracking and remote camera/microphone activation. Exciting to children and practical to parents, it's an ideal alternative to a smartphone this Christmas . The watch is packed with exciting apps, including built-in games, calculator and alarm clock. The video calling function allows them to connect with you or friends in an instant, futuristic fashion. Gel Blaster SURGE Price: £59.99 (currently £34.99) An advanced blaster with no mess or clean-up technology, meaning you can battle indoors or outdoors.. It comes with 10,000 water-based Gellets which are non-toxic, non-staining, non-irritating and pet safe. Bursting on impact, they provide safe and mess-free fun. SURGE has two blast modes - Single Shot for honing your precision and training, and Fully Automatic for dominating the competition. GoCube Price: £59.99 The iconic Rubik’s cube reimagined, the GoCube is an app-enabled speed cube that allows anyone to learn how to solve the cube. This award-winning puzzle toy and dedicated app helps users to master the cube thanks to a fun and interactive step-by-step tutorial, tracking progress in real-time. Users can play and practise with multiple mini-games to choose from or battle with friends and other cubers online to get on the global leader board. Whether learning, improving, battling or playing, GoCube takes cubing to the next level. GoBalance Play Price: £79.99 The GoBalance Play, combined with its engaging and interactive games, makes exercising fun for the entire family. This smart wobble balance board, designed by physiotherapists, enhances motor skills, core strength, flexibility, coordination and concentration. Connecting to any Android or iOS device via Bluetooth, a free app offers interactive and challenging games such as snowboarding or mini golf, that make exercising enjoyable whilst helping to develop physical and mental abilities.
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Bell Potter names more of the best ASX shares to buy in DecemberWheel of Fortune viewers were less than impressed this evening as they settled in to watch the ITV show's Christmas special. The festive edition, hosted by Graham Norton, featured celebrities Richard E Grant, Tyler West, and Joanna Page spinning the wheel in an attempt to win cash for their chosen charities. The game involves contestants guessing phrases and words to win the largest possible jackpot without losing a turn or going bankrupt. As the Christmas special was broadcast, viewers quickly expressed their dissatisfaction on social media. One viewer tweeted: "Omg how easy is this show now, I got mince pies before he even picked the letters, actually even my dog got the answer." Another commented: "It's so boring sorry. #WheelOfFortune." A third viewer remarked: "At least make it challenging #wheeloffortune," while another was puzzled: "How did he get not get that #wheeloffortune." Graham Norton hosted the show (Image: ITV) Read More Related Articles Coronation Street confirms how long Rob Donovan is really back for as actor issues four-word message Read More Related Articles Coronation Street's Joel Deering star gets 'best present ever' after exit as storyline 'not ended' The episode's simplicity sparked frustration among fans, particularly when the phrase 'mince pies' was deemed too straightforward. The confusion continued as Joanna Page struggled with the phrase 'Ding Dong Merrily on High Heels', which she only solved after all the letters were revealed, much to the audience's bemusement. This Christmas special sets the stage for a nine-episode run of the regular series, which is set to commence in the New Year. Graham will be back for a new series next year (Image: ITV) Graham Norton, the host of the show, expressed his enthusiasm about the return of the series: "I'm thrilled we are coming back for a second series to challenge more contestants to solve more word puzzles and hopefully they come away with even more cash. It's a game of skill and luck, so you just never know which way it will go and I'm excited to see who can hold their nerve against the wheel." Katie Rawcliffe, from ITV's Head of Entertainment Commissioning, also shared her excitement regarding the show's comeback: "We are excited to bring back this iconic game show for a second series after a successful launch earlier this year. Graham with his wit and humour is the perfect host for this fun, exciting, fast paced game of luck and skill." *Wheel of Fortune is available to catch up on ITVX.The Vicar & Archdeacon, Molete Archdeaconry of the Diocese of Ibadan, Ven. Olusegun Faleye has urged clergymen and Nigerian leaders in general, to learn to be humble, moderate, selfless and honest in their callings to encourage upcoming ones to live a holy life, thus encouraging the masses to live righteous lifestyles. In his sermon at the St. Anne’s Church, Molete, Ibadan on Sunday, in commemoration of the 70th Anniversary of the Ibadan Branch of the Nigerian Bar Association (NBA), Faleye, who deplored the socio-political and economic downturn in Nigeria, preached against impersonation and dishonesty, noting that whatever one becomes in life or accumulated on earth, is just temporal. The Christian lawyers among the congregants who were addressed in the sermon included: the Vice Chairman of the Ibadan NBA Branch, Mr Kehinde Oyewale, who led other lawyers including Prof. John Akintayo (Dean of the Faculty, of Law, University of Ibadan, who is also a former Chairman of the Branch); Pa Mathew Adepoju (NBA Patron); Mr Olayinka Esan (ex-Chairman); Mr Ademola Ademidun, Mr Yomi Aliu (SAN), and the Chief Registrar, Mrs. Ogunrin, who represented the Chief Judge of the State, Justice Iyabo Yerima, among others. The Vicar counselled leaders in general on the tenets and advantages of being honest, not being proud; and refraining from impersonation just like John the Baptist did in the Bible when he was applauded for many great things he did and so was asked by the people whether he was the Christ that was being expected. “He said, ‘I am not the Christ you are expecting. I am just His forerunner. As you are honouring me when Christ comes, you will see that I cannot even unbuckle His sandals”. Reading from the Book of John Chapter 1, verses 19-28, the Vicar said, “John just came to fulfil his role as forerunner, fore bearer and herald of Christ. He was the official messenger of Christ. Many of us who are Men of God arrogate to ourselves what we are not. Some even present themselves as Christ himself. “We should learn to be humble. Many of us Pastors, GOs, Reverends, Apostles, and Band bishops believe that younger ones must be suppressed and not allowed to grow if they perform well. “Whenever any miracle is done, be it real or fake, all radio stations must air it; all television stations must broadcast it. Some will even preach and when the congregants don’t clap for them, they compel them to clap. All this is profane. “John in the Bible tells us that all the things we run after in life are just temporal. So, as leaders, we should always live an exemplary life of honesty, humility, love, and transparency, while also encouraging others to live”, Faleye urged. The Vicar, therefore, hinted of some signs of end-time which everybody must be wary of, among them: “age of technology; the spread of the gospel; environmental challenges including climate change and even COVID-19; fake miracles, as well as, lovelessness”.
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