Giants face challenge in hosting Ravens, trying to end 8-game skidThis Mysterious New York Military Base Inspired Stranger ThingsVMT-01 is under clinical development by Perspective Therapeutics and currently in Phase II for Metastatic Melanoma. According to GlobalData, Phase II drugs for Metastatic Melanoma have a 36% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval. VMT-01 overview VMT-01 is under development for the treatment of metastatic melanoma. The drug candidate is a MCR1-targeted radionuclide (90Y) therapy. therapy. It acts by targeting melanocyte stimulating hormone receptor (Melanocortin Receptor 1 or MSHR or MC1R). it is administered by intravenous route. Perspective Therapeutics overview Perspective Therapeutics, formerly known as Isoray, Inc., is a medical technology company. It specializes in the development and distribution of isotope-based personalized brachytherapy products and devices for advanced cancer treatments. The company’s core product is the Cesium-131 brachytherapy seed, a unique radioisotope seed used in the treatment of various cancers, including prostate, brain, head and neck, and lung cancers. Brachytherapy involves placing the radiation sources close to the tumor site to destroy the cancer cells. Perspective Therapeutics serves medical centers, hospitals, and clinics. It operates primarily in the US. Perspective Therapeutics is headquartered in Richland, Washington, the US. For a complete picture of VMT-01’s drug-specific PTSR and LoA scores, This content was updated on 12 April 2024 From Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors. , the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article. GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s .
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NASHVILLE, Tenn. (AP) — The Tennessee Titans have the slimmest of playoff hopes and must win out to have any chance of keeping them alive. Figuring out who they are would be a first step in the right direction. The Titans (3-9) also must bounce back from last week's ugly loss at Washington that cost this franchise yet another chance to string together consecutive wins for the first time in more than two years. “We know that this is a big opportunity for us to develop as a team and to create and to continue developing our identity,” quarterback Will Levis said. “And so we’re going to make sure that we do our best throughout these next few weeks to do that.” The Jacksonville Jaguars (2-10) lost Trevor Lawrence for the rest of the season after the hit he took from Texans linebacker Azeez Al-Shaair in last week's 23-20 loss to Houston. Their already dim playoff hopes were extinguished Monday night when Denver won. That leaves the Jaguars playing for pride and potentially drafting No. 1 overall for the third time in five years. “It’s all about how you finish,” tight end Evan Engram said. “How we finish probably won’t erase the feeling we have of the season. But as the pride of this franchise, the pride of the team, it’s definitely worth going to finish strong and going to get some wins and fighting for that.” The Titans went into Washington with one of the NFL's stingiest defenses and wound up shredded, giving up a season-worst 267 yards rushing. Defensive coordinator Dennard Wilson said, “We can’t allow what happened last week to happen again.” Wide receiver Calvin Ridley says he's excited to see some old teammates Sunday and downplayed a question about how close Jacksonville's offer to keep him last March might've been when he chose to sign with division rival Tennessee instead. “Doesn't matter right now,” Ridley said. “I'm excited for this week. Jags come in here, play with my boys. I'm excited.” Ridley played one season with Jacksonville after the Jaguars traded for him . He had 76 catches for 1,016 yards and eight TDs last season with the Jaguars. So far this season, Ridley has 43 receptions for 679 yards and three TDs. “I just know I'm going to be ready,” Ridley said. Jacksonville has lost 16 consecutive games when tied or trailing at halftime. It’s a complete flip from the 2022 season, in which the Jaguars rallied to beat Dallas, the Las Vegas Raiders and Tennessee down the stretch to make the playoffs. The 20-16 victory against the Titans in the regular-season finale that year is the last time coach Doug Pederson’s team has come from behind to win after trailing or being tied at the break. Tennessee led 13-7 at the half in that one and was minutes from winning a third straight AFC South title . Jaguars defensive end Josh Hines-Allen needs 4 1/2 sacks to break the franchise record of 55 held by Tony Brackens. Hines-Allen has at least half a sack in four consecutive games against Tennessee, which has given up 43 sacks in 2024. “My family knows about it probably more than me,” Hines-Allen said. “My wife tells me all the time, ‘Hey, get that record. All you just need is four sacks.’ Like, you can just (get) four sacks. “I had a couple games last year where I had three, so I can’t say it’s out of the realm. But I never had four sacks; don’t know what it feels like to do that in one game. But hopefully speak it into existence.” Mac Jones will be starting at quarterback and is 0-2 with the Jaguars this season. He has one more interception (three) than touchdown passes (two) in five appearances. The Titans are looking to see if Levis can keep building on his strong play of the past month and start turning those into wins. Levis is 1-3 since returning from a strained throwing shoulder. He has seven TD passes with two interceptions for a 101.3 passer rating in his past four games. He also is completing 61.7% of his passes for 960 yards. “The cool thing right now for Will is that as we’ve corrected things, he’s corrected them,” Titans coach Brian Callahan said . “And that’s been really fun to watch as he’s made adjustments from game to game, sometimes even from in the game made an adjustment to a coverage or a read, and that part’s been good to see.” AP Pro Football Writer Mark Long in Jacksonville, Florida, contributed to this report. AP NFL: https://apnews.com/hub/nfl
Film Certification Board: Ambitious plans, lingering challengesResiquimod is under clinical development by SURGE Therapeutics and currently in Phase II for Non Muscle Invasive Bladder Cancer (NMIBC) (Superficial Bladder Cancer). According to GlobalData, Phase II drugs for Non Muscle Invasive Bladder Cancer (NMIBC) (Superficial Bladder Cancer) have a 72% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval. Resiquimod overview Resiquimod (STM-416) is under development for the prevention of recurrence and/or progression after transurethral resection of bladder tumor (TURBT) in non-muscle invasive bladder cancer (NMIBC). The drug candidate is an imidazoquinolinamine which acts by targeting toll like receptor 7 (TLR7) and toll like receptor 8 (TLR8). It is administered intraoperatively in the form of biodegradable gel. SURGE Therapeutics overview SURGE Therapeutics (SURGE) is a provider of intraoperative immunotherapy services for cancer patients that offers an injectable biodegradable hydrogel and allows prolonged, localized free-up of most cancers immunotherapy. The company is headquartered in Cambridge, Massachusetts, the US. For a complete picture of Resiquimod’s drug-specific PTSR and LoA scores, This content was updated on 12 April 2024 From Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors. , the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article. GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s .
(All times Eastern) Schedule subject to change and/or blackouts Thursday, Dec. 26 COLLEGE FOOTBALL 2 p.m. ESPN — The GameAbove Sports Bowl: Pittsburgh vs. Toledo, Detroit 5:30 p.m. ESPN — The Rate Bowl: Rutgers vs. Kansas St., Phoenix 9 p.m. ESPN — The 68 Ventures Bowl: Arkansas St. vs. Bowling Green, Mobile, Ala. IIHF HOCKEY (MEN’S) Noon NHLN — World Junior Championship Group Stage: Slovakia vs. Sweden, Group B, Toronto 2:30 p.m. NHLN — World Junior Championship Group Stage: U.S. vs. Germany, Group A, Ottawa, Ontario 5 p.m. NHLN — World Junior Championship Group Stage: Czechia vs. Switzerland, Group B, Toronto 7:30 p.m. NHLN — World Junior Championship Group Stage: Finland vs. Canada, Group A, Ottawa, Ontario NBA BASKETBALL 7 p.m. NBATV — Oklahoma City at Indiana 10 p.m. NBATV — Utah at Portland NFL FOOTBALL 8:15 p.m. PRIME VIDEO — Seattle at Chicago SOCCER (MEN’S) 7:30 a.m. USA — Premier League: Everton at Manchester City 9:55 a.m. CBSSN — EFL League One: Blackpool vs. Wrexham 10 a.m. USA — Premier League: Aston Villa at Newcastle United 12:30 p.m. USA — Premier League: Manchester United at Wolverhampton 12:40 p.m. CBSSN — SPFL: Rangers at St. Mirren 3 p.m. USA — Premier League: Leicester City at Liverpool TENNIS 9 p.m. TENNIS — United Cup: Spain v. Kazakhstan 4 a.m. (Friday) TENNIS — United Cup: China v. Brazil 6 a.m. (Friday) TENNIS — United Cup: China v. Brazil The Associated Press created this story using technology provided by Data Skrive TV listings provided by LiveSportsOnTV .The new Karl Lagerfeld has arrived at Chanel. Here’s what to expect
Distilled Water Stills Market Set for Exceptional Growth from 2024 to 2032 12-25-2024 07:36 PM CET | Business, Economy, Finances, Banking & Insurance Press release from: Prudent Markets Distilled Water Stills Market The Distilled Water Stills Market 2024-2023 report provides a comprehensive analysis of Types (Stainless Steel, Brass, Glass, Others), Application (Household, Commercial, Industrial, Others), Analysis of Industry Trends, Growth, and Opportunities, R&D landscape, Data security and privacy concerns Risk Analysis, Pipeline Products, Assumptions, Research Timelines, Secondary Research and Primary Research, Key Insights from Industry Experts, Regional Outlook and Forecast, 2024-2032. Major Players of Distilled Water Stills Market are: Polar Bear Water Group, M Technique Co., Ltd., Justdial, Doctor Water, Megahome Co., Ltd., The Water Delivery Company, Zhejiang Getidy Medical Instrument Co.,Ltd., GPC Medical Ltd., TIN HANG TECHNOLOGY LIMITED, LAUDA DR. R. WOBSER GMBH & CO. 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The Bears will see the return of defensive tackle Gervon Dexter on Thursday night. He was questionable with a knee injury that kept him out of the Week 16 loss to the Lions. Dexter has 44 tackles, five sacks, 16 quarterback hits and two fumble recoveries in 13 games this season. The Bears’ inactives are left guard Teven Jenkins (calf), defensive tackle Zacch Pickens, running back Travis Homer (hamstring), safety Elijah Hicks (ankle/foot), linebacker Noah Sewell and safety Tarvarius Moore (knee). The Seahawks’ inactives are quarterback Jaren Hall, tight end Brady Russell (foot), offensive tackle Michael Jerrell, wide receiver Cody White, linebacker Patrick O’Connell and cornerback Nehemiah Pritchett. Hall will serve as the emergency, third quarterback.The heavily awaited flyweight title fight between Alexandre Pantoja and rookie Kai Asakura was one of the ages. It was the last Pay-Per-View event for the year. After initially being promoted a co-main event, it was eventually moved up to the main event after Welterweight champion Belal Muhammad had to pull out of the match, which would have been his first defense of his title against the challenger, Shavkat Rakhmonov. ‘The Cannibal’ Pantoja came out with power. He quickly established his dominance over Asakura by getting him down on the mat with a powerful knee to the head of Asakura. In the initial round, Pantoja took over and proved why he’s nicknamed ‘The Cannibal’. The Game Changer The champ showed the newcomer why he was there. Pantoja quickly flanked to Asakura’s back and proceeded to choke Asakura unconscious in the second round. This was Asakura’s first time in the UFC octagon. The Champion is Reclaimed Alexandre Pantoja was crowned flyweight champion of the world once again. This was Pantoja’s third successful defense of his title. As reported by MMAjunki.usatoday.com, in his post-fight interview, Alexandre Pantoja called out rival Demetrious Johnson saying, “I’m the GOAT here. If you want to prove you’re the GOAT, come back.” Dec 7, 2024; Las Vegas, Nevada, UNITED STATES; Alexandre Pantoja (red gloves) fights Kai Asakura (blues gloves) at T-Mobile Arena. Mandatory Credit: Stephen R. Sylvanie-Imagn Images According to Bloodyelbow.com, Pantoja could end up in a rematch with either Brandon Moreno or Brandon Royval. This article first appeared on Dice City Sports and was syndicated with permission.
Stocks closed higher on Wall Street, giving the market its fifth gain in a row and notching another record high for the Dow Jones Industrial Average. The S&P 500 rose 0.3% Friday. The Dow added 1%, and the Nasdaq composite tacked on 0.2%. Retailers had some of the biggest gains. Gap soared after reporting quarterly results that easily beat analysts’ estimates. EchoStar fell after DirecTV called off its purchase of that company’s Dish Network unit. European markets closed mostly higher and Asian markets ended mixed. Treasury yields held relatively steady in the bond market. Crude oil prices gained ground. THIS IS A BREAKING NEWS UPDATE. AP’s earlier story follows below. Stocks rose on Wall Street in afternoon trading Friday, keeping the market on track for its fifth straight gain. The S&P 500 was up 0.2% and was solidly on track for a weekly gain that will erase most of last week's loss. The Dow Jones Industrial Average climbed 333 points, or 0.8%, and the Nasdaq composite was essentially flat with a gain of less than 0.1% as of 3:07 p.m. Eastern. Markets have been volatile over the last few weeks, losing ground in the runup to elections in November, then surging following Donald Trump's victory, before falling again. The S&P 500 has been steadily rising throughout this week to within close range of its record. “Overall, market behavior has normalized following an intense few weeks,” said Mark Hackett, chief of investment research at Nationwide, in a statement. Several retailers jumped after giving Wall Street encouraging financial updates. Gap soared 10.8% after handily beating analysts' third-quarter earnings and revenue expectations, while raising its own revenue forecast for the year. Discount retailer Ross Stores rose 1.5% after raising its earnings forecast for the year. EchoStar fell 2.4% after DirecTV called off its purchase of that company's Dish Network unit. Smaller company stocks had some of the biggest gains. The Russell 2000 index rose 1.8%. A majority of stocks in the S&P 500 were gaining ground, but those gains were kept in check by slumps for several big technology companies. Nvidia fell 3.3%. Its pricey valuation makes it among the heaviest influences on whether the broader market gains or loses ground. The company has grown into a nearly $3.6 trillion behemoth because of demand for its chips used in artificial-intelligence technology. Intuit, which makes TurboTax and other accounting software, fell 5.6%. It gave investors a quarterly earnings forecast that fell short of analysts’ expectations. Facebook owner Meta Platforms fell 0.8% following a decision by the Supreme Court to allow a multibillion-dollar class action investors’ lawsuit to proceed against the company. It stems from the privacy scandal involving the Cambridge Analytica political consulting firm. European markets closed mostly higher and Asian markets ended mixed. Crude oil prices rose. Treasury yields held relatively steady in the bond market. The yield on the 10-year Treasury fell to 4.41% from 4.42% late Thursday. In the crypto market, Bitcoin hovered around $99,000, according to CoinDesk. It has more than doubled this year and first surpassed the $99,000 level on Thursday. Retailers remained a big focus for investors this week amid close scrutiny on consumer spending habits headed into the holiday shopping season. Walmart, the nation's largest retailer, reported a quarter of strong sales and gave investors an encouraging financial forecast. Target, though, reported weaker earnings than analysts' expected and its forecast disappointed Wall Street. Consumer spending has fueled economic growth, despite a persistent squeeze from inflation and high borrowing costs. Inflation has been easing and the Federal Reserve has started trimming its benchmark interest rates. That is likely to help relieve pressure on consumers, but any major shift in spending could prompt the Fed to reassess its path ahead on interest rates. Also, any big reversals on the rate of inflation could curtail spending. Consumer sentiment remains strong, according to the University of Michigan's consumer sentiment index. It revised its latest figure for November to 71.8 from an initial reading of 73 earlier this month, though economists expected a slight increase. It's still up from 70.5 in October. The survey also showed that consumers' inflation expectations for the year ahead fell slightly to 2.6%, which is the lowest reading since December of 2020. Wall Street will get another update on how consumers feel when the business group The Conference Board releases its monthly consumer confidence survey on Tuesday. A key inflation update will come on Wednesday when the U.S. releases its October personal consumption expenditures index. The PCE is the Fed's preferred measure of inflation and this will be the last PCE reading prior to the central bank's meeting in December. Damian J. Troise And Alex Veiga, The Associated PressNone
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