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Dear Eric: When my only son and his wife got married and had kids, I was informed that Christmas Day would just be for them to celebrate. I said OK. For decades, I have given my son and his family (wife and two kids) really nice gifts for Christmas. We are talking about hundreds of dollars. For a while, I would receive a small gift, such as a bottle of homemade vanilla, a rose-scented tin of salve made by a friend of the wife or a coffee cup or some such as a gift from the family. Same with my birthday. I have never received a gift from the grandkids. Last year, I let them know I would no longer be “exchanging” gifts with the parents but gifts to the grandkids (who are now teenagers with jobs) will continue. That year, I got them electronics and hoodies. I got nothing from anyone. Not even an acknowledgement from the kids. I have always had to deliver the gifts or call to see if they received them. This year, it is only going to be a Christmas card. Am I being overly sensitive? — Empty Stocking Dear Stocking: No, you are not being overly sensitive. Every family has their own traditions and needs. And no one is obligated to give — or accept — a gift. But it sure does make me sad that your desire to make this holiday special isn’t being reciprocated. Part of it may be a misalignment of expectations. You’ve given generously, into the hundreds of dollars. I’m curious if your son and daughter-in-law have different values or wants around gifting that are either not being expressed or not being heard. They should tell you clearly. Similarly, when you decided to stop giving gifts to the adults, I’m curious if your expectations were that your son would realize that you weren’t getting what you wanted and make a change. It’s worth talking it through a little more but try to focus on the want behind the want. I suspect that what you’re craving is connection — and perhaps an invitation to the family Christmas. It makes sense that you’d try to show your love from a distance through gift-giving and it makes sense that it would hurt not to have it reciprocated. But perhaps the tradition of gifts is getting in the way on both sides. If you’d like to be invited or would like to find an alternate way of celebrating and being together, that’s a great gift to ask for. Dear Eric: I was riding my bicycle when, unbeknownst to me, my wallet fell out of my pocket. My driver’s license, credit cards and about $200 in cash were in the wallet. Later that day I received a telephone call from a cyclist who found my wallet on his ride and told me that I could come over to pick it up. What, if any, reward would be appropriate? I gave a $30 bottle of wine. — Grateful Cyclist Dear Cyclist: How lucky that your path crossed with such a good fellow citizen! Etiquette experts agree that the amount of a reward in situations like this is really up to you. So, the bottle of wine you gave works. My only suggestion, however, would be that, if this ever happens again (fingers crossed your wallet stays in your pocket from now on), you check with the recipient to make sure that they drink wine. It’s the thought that counts, but you don’t want your grateful efforts to put someone else in an uncomfortable or dangerous situation.
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AP Sports SummaryBrief at 6:49 p.m. ESTIn Georgia Tech's final nonconference contest, the Yellow Jackets host Alabama A&M in Atlanta on Saturday afternoon. Georgia Tech (5-7) has yet to beat a power conference team this season, earning wins over West Georgia, Texas Southern, Charleston Southern, Central Arkansas and UMBC. Losers in four of their last five games, the Yellow Jackets were stomped at home last time out by then-No. 5 Duke, extending a concerning trend against high-major opponents this season. In its six meetings with power conference teams, Georgia Tech has been outscored by an average of 14.3 points per game. Making matters worse for head coach Damon Stoudamire's team has been the absences of Kowacie Reeves Jr. (ankle) and Luke O'Brien (foot). Reeves, who is averaging 9.3 points in six games, hasn't played since Nov. 27, while O'Brien (6.4 ppg, 4.4 rebounds per game) didn't play in the loss to Duke. "Kowacie and Luke are both seniors, they've both got experience, but you can't really dwell on it," Stoudamire said. "They're injured but I'm not going to allow that to be an excuse. I'm not going to go down that path. They're missed, obviously, but you have be a next-man-up team at times." Lance Terry leads the team with 14.8 points per game, followed by Baye Ndongo's 13.0 and Naithan George's 10.4. Saturday marks Alabama A&M's last nonconference game before SWAC play begins Jan. 4 against Arkansas-Pine Bluff. The Bulldogs (4-8) have dropped their last five games since a Nov. 23 win over Coastal Carolina. Led by AC Bryant's 13.1 points per game and Chad Moodie's 12.6, Alabama A&M is vying for what would be a monumental victory. "We're doing some things now that are going to make the other team prepare," Bulldogs coach Otis Hughley Jr. said. "And you know that you're coming out of a contest when you play us." Georgia Tech is 6-0 all-time against the Bulldogs, including a 70-49 win on Dec. 9, 2023. --Field Level Media
MALVERN, PA — TELA Bio, Inc. (NASDAQ: TELA) announced its participation in Piper Sandler’s 36th Annual Healthcare Conference, a premier event showcasing leading innovations in the healthcare sector. Mark your calendars for December 3rd, 2024, at 12:00 pm ET, when TELA Bio’s management will take the stage to share exciting developments and insights into our cutting-edge technologies. This presentation is a unique opportunity for investors, industry professionals, and enthusiasts to gain a deeper understanding of TELA Bio’s strategic vision and growth trajectory. Join live or catch the archived webcast later, accessible through our investor relations site at ir.telabio.com . Don’t miss this opportunity to connect with industry leaders and explore the future of healthcare innovation with TELA Bio! For the latest news on everything happening in Chester County and the surrounding area, be sure to follow MyChesCo on Google News and MSN .
Canadian Prime Minister Justin Trudeau's government on Monday survived a third vote of no confidence in as many months, brought by his main Tory rival. The minority Liberal government got the support of the New Democratic Party (NDP), a small leftist faction once aligned with the ruling Liberals, to defeat the motion 180-152. The text of the proposition echoed NDP leader Jagmeet Singh's own past criticisms of Trudeau since breaking off their partnership in late August, calling him "too weak, too selfish." Neither Singh nor Trudeau were present for the vote. The House of Commons has been deadlocked most of this fall session by an unprecedented two-month filibuster by the Conservatives. But Speaker Greg Fergus, in a rare move, ordered a short break in the deadlock to allow for this and other possible confidence votes, and for lawmakers to vote on a key spending measure. MPs are scheduled to vote Tuesday on the spending package, which includes funds for social services, disaster relief and support for Ukraine. With a 20-point lead in polls, Conservative leader Pierre Poilievre has been itching for an election call since the NDP tore up its coalition agreement with the Liberals. But the NDP and other opposition parties, whose support is needed to bring down the Liberals, have so far refused to side with the Conservatives. Two no-confidence votes brought by the Tories in September and October failed when the NDP and the separatist Bloc Quebecois backed the Liberals. In Canada's Westminster parliamentary system, a ruling party must hold the confidence of the House of Commons, which means maintaining support from a majority of members. The Liberals currently have 153 seats, versus 119 for the Conservatives, 33 for the Bloc Quebecois, and the NDP's 25. Trudeau swept to power in 2015 and has managed to hold on through two elections in 2019 and 2021. amc/bs/bjt
All Three Patients Treated in First Dose Cohort Administered Fludarabine-free Conditioning and Show Rapid, Deep, and Sustained B-cell Depletion with Favorable Safety Profile First Patient to Reach 6-Month Follow-up Remains in DORIS Clinical Remission and Free of All Immunosuppressive Therapies Company Plans to Initiate Dose Expansion at First Dose Level of 360M Cells SAN DIEGO, Dec. 09, 2024 (GLOBE NEWSWIRE) -- Fate Therapeutics, Inc. (NASDAQ: FATE), a clinical-stage biopharmaceutical company dedicated to bringing a first-in-class pipeline of induced pluripotent stem cell (iPSC)-derived cellular immunotherapies to patients with cancer and autoimmune disorders, today presented new clinical and translational data from the Company’s FT819 Phase 1 Autoimmunity study for moderate-to-severe systemic lupus erythematosus (SLE) at the American Society of Hematology (ASH) Annual Meeting being held in San Diego, CA. The first three study patients, each of whom presented with active lupus nephritis (LN) despite having been treated with multiple standard-of-care therapies, received fludarabine-free conditioning followed by a single dose of FT819 at 360 million cells. There were no dose-limiting toxicities (DLTs), no events of any grade of cytokine release syndrome (CRS), immune effector-cell associated neurotoxicity syndrome (ICANS), or graft-versus-host disease (GvHD), and rapid, deep, and sustained elimination of CD19+ B cells in the periphery was observed during the first month of treatment. FT819 is the Company’s off-the-shelf, CD19-targeted, 1XX CAR T-cell product candidate comprised of CD8αβ+ T cells with a memory phenotype and high CXCR4 expression to promote tissue trafficking. “We continue to be very pleased with early clinical observations of fludarabine-free conditioning and FT819 off-the-shelf, CAR T-cell therapy in patients with moderate-to-severe SLE. The remarkable experience of the first patient treated in April is ongoing, as the patient remains on-study in drug-free clinical remission. In addition, the initial clinical and translational data from the two additional patients treated at the first dose level continue to support the potential for disease transformation,” said Bob Valamehr, President of Research and Development of Fate Therapeutics. “We are now initiating dose expansion at this first dose level to accelerate development, and are also escalating dose based on the favorable safety profile observed. In addition, I am pleased to announce that the first patient has now been treated with FT819 as an add-on to maintenance therapy without conditioning chemotherapy. We believe our therapeutic approach is highly-differentiated and has the potential to transform disease outcomes without requiring patient apheresis, discontinuation of maintenance therapy, intense conditioning chemotherapy, and extended hospitalization.” FT819 Phase 1 Autoimmunity Study The ongoing multi-center, Phase 1 clinical trial for patients with moderate-to-severe SLE is designed to evaluate the safety, pharmacokinetics, and anti-B cell activity of FT819 (NCT06308978). The first three patients, all of whom presented with active LN despite having been treated with multiple standard-of-care therapies, received fludarabine-free conditioning consisting of either cyclophosphamide alone or bendamustine alone, followed by a single dose of FT819 at 360 million cells. In all three patients, FT819 was detected in the peripheral blood and rapid, deep, and sustained elimination of CD19+ B cells in the periphery was observed during the first month of treatment. All three patients remain on-study, and there have been no DLTs and no events of any grade of CRS, ICANS, or GvHD. Based on these clinical observations, the Company is initiating dose expansion in up to 10 patients at this first dose level, and is also escalating dose to 720 million cells. The Company’s FT819 Phase 1 Autoimmunity study also includes a second treatment arm to assess the safety, pharmacokinetics, and anti-B cell activity of a single dose of FT819 as an add-on to maintenance therapy without conditioning chemotherapy in patients with SLE. The first patient has now been treated in this second arm, which is being conducted in parallel with the study’s conditioning arm. FT819 Patient 1 Case Study The first patient treated in the Phase 1 Autoimmunity study presented with active LN and severe disease, which was marked by renal BILAG A (British Isles Lupus Assessment Group) disease activity score based on biopsy, SLEDAI-2K (Systemic Lupus Erythematosus Disease Activity Index) score of 20, FACIT-Fatigue (Functional Assessment of Chronic Illness Therapy-Fatigue) score of 33 (range 0-52, where a score of 52 indicates no fatigue) and PGA (Physician Global Assessment) score of 2.5 (where a score of 3 indicates most severe activity). Following administration of fludarabine-free conditioning and treatment with a single dose of FT819 at 360 million cells, the patient was discharged from the hospital without notable adverse events (AEs) after a protocol-required three-day stay. Rapid elimination of CD19+ B cells in the periphery was observed following treatment, and B-cell recovery by Month 3 was predominantly comprised of naïve, non-class switched B cells with near-complete elimination of switched memory B cells and deep depletion of plasmablasts, indicative of an immune reset. The patient reported that her debilitating fatigue had entirely resolved without further treatment, and treatment with methylprednisolone was discontinued at Month 3. The patient achieved DORIS (definition of remission in SLE) clinical remission, including with resolution of arthritis and active urinary sediment and with a substantial reduction in proteinuria, as of Month 6 follow-up. The patient continues on-study, in DORIS clinical remission, and remains free of all immunosuppressive therapy. iPSC-derived CAR T-cell Product Platform The Company also highlighted the scientific progress of its proprietary iPSC-derived CAR T-cell product platform at the ASH Annual Meeting. In an oral presentation entitled “ Off-the-shelf Product Candidate Incorporates Novel Sword & Shield Technology Designed to Promote Functional Persistence without Conditioning Chemotherapy ”, the Company compared its novel Sword & Shield technology, which utilizes a 4-1BB-targeted CAR (ADR) alongside the complete knock-out of CD58 (CD58KO) to both target and evade host alloreactive immune cells, to other host immune evasion strategies. In preclinical studies of allogeneic models, the Company showed that its Sword and Shield Technology specifically engaged with alloreactive T cells and supported functional persistence while avoiding the killing of general host T cells and activated anti-tumor T cells. This unique observation was not seen with other approaches that are either too broad and undesirably eliminate most of the host immune system or have limited coverage and cannot adequately protect the allogeneic cell product. In a second presentation entitled “ Development of Induced Pluripotent Stem Cell-Derived T Cells Exhibiting Phenotypic and Functional Attributes of Primary CAR T Cells ”, the Company conducted a series of high-resolution analyses to show stimulated iPSC-derived T cells elicit primary T-cell like activation, proliferation, transcriptional and functional program engagement, and iPSC-derived CAR T cells uniquely emulate antigen-mediated response similar to primary-derived autologous CAR T cells. About Fate Therapeutics’ iPSC Product Platform Human induced pluripotent stem cells (iPSCs) possess the unique dual properties of unlimited self-renewal and differentiation potential into all cell types of the body. The Company’s proprietary iPSC product platform combines multiplexed-engineering of human iPSCs with single-cell selection to create clonal master iPSC lines. Analogous to master cell lines used to mass produce biopharmaceutical drug products such as monoclonal antibodies, the Company utilizes its clonal master iPSC lines as a starting cell source to manufacture engineered cell products which are well-defined and uniform in composition, can be stored in inventory for off-the-shelf availability, can be combined and administered with other therapies, and can potentially reach a broad patient population. As a result, the Company’s platform is uniquely designed to overcome numerous limitations associated with the manufacture of cell therapies using patient- or donor-sourced cells. Fate Therapeutics’ iPSC product platform is supported by an intellectual property portfolio of over 500 issued patents and 500 pending patent applications. About Fate Therapeutics, Inc. Fate Therapeutics is a clinical-stage biopharmaceutical company dedicated to bringing a first-in-class pipeline of induced pluripotent stem cell (iPSC)-derived cellular immunotherapies to patients with cancer and autoimmune diseases. Using its proprietary iPSC product platform, the Company has established a leadership position in creating multiplexed-engineered master iPSC lines and in the manufacture and clinical development of off-the-shelf, iPSC-derived cell products. The Company’s pipeline includes iPSC-derived natural killer (NK) cell and T-cell product candidates, which are selectively designed, incorporate novel synthetic controls of cell function, and are intended to deliver multiple therapeutic mechanisms to patients. Fate Therapeutics is headquartered in San Diego, CA. For more information, please visit www.fatetherapeutics.com . Forward-Looking Statements This release contains "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995 including statements regarding the safety and therapeutic potential of the Company’s iPSC-derived CAR T-cell product candidates, including FT819, the advancement of and plans related to the Company's product candidates, clinical studies and preclinical research and development programs, the Company’s progress, plans and timelines for the clinical investigation of its product candidates, including the expected clinical development plans for FT819, the initiation and continuation of enrollment in the Company’s clinical trials, the initiation of additional clinical trials and additional dose cohorts in ongoing clinical trials of the Company’s product candidates, the timing and availability of data from the Company’s clinical trials, the therapeutic and market potential of the Company’s research and development programs and product candidates, the Company’s clinical and product development strategy, and the Company’s expectations regarding progress, plans, and timelines. These and any other forward-looking statements in this release are based on management's current expectations of future events and are subject to a number of risks and uncertainties that could cause actual results to differ materially and adversely from those set forth in or implied by such forward-looking statements. These risks and uncertainties include, but are not limited to, the risk that the Company’s research and development programs and product candidates, including those product candidates in clinical investigation, may not demonstrate the requisite safety, efficacy, or other attributes to warrant further development or to achieve regulatory approval, the risk that results observed in prior studies of the Company’s product candidates, including preclinical studies and clinical trials, will not be observed in ongoing or future studies involving these product candidates, the risk of a delay or difficulties in the initiation and conduct of, or enrollment of patients in, any clinical trials, the risk that the Company may cease or delay preclinical or clinical development of any of its product candidates for a variety of reasons (including requirements that may be imposed by regulatory authorities on the initiation or conduct of clinical trials, changes in the therapeutic, regulatory, or competitive landscape for which the Company’s product candidates are being developed, the amount and type of data to be generated or otherwise to support regulatory approval, difficulties or delays in patient enrollment and continuation in the Company’s ongoing and planned clinical trials, difficulties or delays in manufacturing or supplying the Company’s product candidates for clinical testing, failure to demonstrate that a product candidate has the requisite safety, efficacy, or other attributes to warrant further development, and any adverse events or other negative results that may be observed during preclinical or clinical development), and the risk that its product candidates may not produce therapeutic benefits or may cause other unanticipated adverse effects. For a discussion of other risks and uncertainties, and other important factors, any of which could cause the Company’s actual results to differ from those contained in the forward-looking statements, see the risks and uncertainties detailed in the Company’s periodic filings with the Securities and Exchange Commission, including but not limited to the Company’s most recently filed periodic report, and from time to time in the Company’s press releases and other investor communications. Fate Therapeutics is providing the information in this release as of this date and does not undertake any obligation to update any forward-looking statements contained in this release as a result of new information, future events or otherwise. Contact: Christina Tartaglia Precision AQ 212.362.1200 christina.tartaglia@precisionaq.com
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Nonetheless, VideoCardz has obtained screenshots of the Legion Go S, which appears to be the device's final name. Not only have promotional images leaked, but so have various hardware specifications. For instance, the Legion Go S utilises a 1,920 x 1,200-pixel IPS display, although Lenovo will advertise the device with 1080p gaming in mind. Furthermore, its AMD Ryzen Z2 Go APU will combine a quad-core Zen 3 CPU with an RDNA 2-derived integrated GPU (iGPU). The latter will arrive under the Radeon 800M series too, despite apparent similarities with the RDNA 2-based Radeon 680M . In short, the Legion Go S will be less powerful than the existing Legion Go (curr. $469.99 - refurbished on Amazon) . Still, the MicroAid listing suggests that the Legion Go S will start at around €600 (~$624) with 16 GB of RAM and 512 GB of storage. Potentially, a 32 GB of RAM and 1 TB of storage option could also be in the works; pricing for this SKU has not emerged yet, though. MicroAid & VideoCardzAshland rings opening bell at NYSE recognizes 100-year anniversaryThe midseason four-game winning streak that lifted the Arizona Cardinals into the playoff picture seemed as though it happened fast. Their subsequent free fall has been even more jarring. The Cardinals could have moved into a tie for first place in the NFC West with a home win over the Seattle Seahawks on Sunday. Instead, they were thoroughly outplayed in a 30-18 loss and are now tied for last in the tightly packed division. Arizona has lost three straight and will face an uphill battle to return to the playoffs for the first time since 2021. The Seahawks (8-5) are in first place, followed by the Rams (7-6), Cardinals (6-7) and 49ers (6-7). Even more daunting for their playoff hopes, the Cardinals lost both of their games against the Seahawks this season, meaning a tiebreaker would go to Seattle. Four games remain. “I just told them we put ourselves in a little bit of a hole now, but all you can do is attack tomorrow, learn tomorrow and have a good week of practice,” second-year coach Jonathan Gannon said. There are plenty of reasons the Cardinals lost to the Seahawks, including Kyler Murray's two interceptions, a handful of holding penalties, a porous run defense and a brutal missed field goal. It all adds up to the fact Arizona is playing its worst football of the season at a time when it needed its best. “I’m sure we’ll stick to our process, but we have to tweak some things,” Gannon said. "I have to tweak some things.” It's probably faint praise, but the Cardinals did make the game interesting in the second half while trying to fight back from a 27-10 deficit. Murray's shovel pass to James Conner for a 2-yard touchdown and subsequent 2-point conversion cut the margin to 27-18. The Cardinals had a chance to make it a one-score contest early in the fourth quarter, but Chad Ryland's 40-yard field goal attempt bounced off the left upright. “I thought we spotted them a lot of points there, but then we battled back,” Gannon said. “I appreciate their effort. That was good. We battled back there, had a couple chances to even cut the lead a little more, but ultimately didn’t get it done." Murray's in a bit of a mini-slump after throwing two interceptions in back-to-back games for the first time in his career. He also didn't do much in the run game against the Seahawks, with 16 yards on three carries. The quarterback's decision-making was nearly flawless for much of the season and the Cardinals need that good judgment to return. “I’m not looking at it like I have to try to be Superman,” Murray said. “I don’t think that’s the answer. I just need to play within the offense like we’ve done for the majority of the season. Today, I didn’t. Like I said, throwing two picks puts yourself behind the eight ball.” Said Gannon: “I thought he stuck in there and made some big time throws, though, but he has to protect the ball a little bit better. That’s not just him, that’s all 11. So there’ll be a lot of corrections off those plays." The defense didn't have its best day, but it's not Budda Baker's fault. The two-time All-Pro safety is having another phenomenal season and was all over the field against the Seahawks, finishing with 18 tackles. Baker's energy is relentless and he's the unquestioned leader of a group that has been better than expected this season, even with Sunday's mediocre performance. Left tackle Paris Johnson Jr. had a tough day, getting flagged for holding three times, though one of those penalties was declined by the Seahawks. The second-year player moved from right tackle to the left side during the offseason and the transition has gone well, but Sunday was a step backward. The Cardinals remain fairly healthy. DL Roy Lopez (ankle) and P Blake Gillikin (ankle) left Sunday's game, but neither injury is expected to be long term. 9 — It looks as if the Cardinals will go a ninth straight season without winning the NFC West. The last time they won the division was 2015 with coach Bruce Arians and a core offense of quarterback Carson Palmer, running back David Johnson and receiver Larry Fitzgerald. The Cardinals are in must-win territory now for any chance at the playoffs. They'll host the New England Patriots on Sunday. AP NFL: https://apnews.com/hub/NFL
Whip up a storm in the kitchen this festive season without breaking a sweat, as creating homemade party food need not be a mammoth task. For those shunning store-bought snacks but craving simplicity, inspiration has arrived from social media creator Charlotte (@lifeofcharlouise). She's given a classic garlic bread a luxury spin, topping a budget shop -bought baguette with creamy brie and rich chorizo to create a sharing sensation that is a must for your New Year's Eve spread. To add some heat, she's whipped up an easy hot honey to drizzle over, reports Daily Record. Posting to TikTok , Charlotte wrote: "Turn this 50p shop bought garlic bread into a fully loaded festive treat. "Anything hot honey I'm obsessed with but adding brie and chorizo just makes it top tier. Another one to add to your buffets this festive season." The clip has been a hit, already amassing 1.2million views and earning acclaim from her followers. User JavEats said: "Chorizo makes everything amazing," while Roksana added: "Wow I really need to try this." A third wrote: "Oooof this looks good." Adelle commented: "This will definitely be on my Xmas menu thank you." To whip up Charlotte's mouth-watering garlic bread recipe and impress your guests this festive season, here's what you need. Hot Honey, Brie and Chorizo Garlic Bread Garlic bread baguette Half a block of brie Half a pack of chorizo slices Honey Chilli flakes Sesame seeds Black onion seeds Chilli jam Fresh parsley Add three tablespoons of honey, two teaspoons of water, some chilli flakes, sesame seeds and black onion seeds to a bowl. Mix together and set aside. Slice your garlic bread the majority of the way down the brie, enough so you get slices and can fit the brie and chorizo in, but so that the slices are attached to each other. Add the sliced brie and chorizo into each slice. Load on the chilli jam and hot honey to the top of the garlic bread. Pop in the oven for 15 minutes or until brie is melted and garlic bread is golden brown. Add an extra drizzle of honey and some fresh parsley, and enjoy!
The will conclude with a winner-take-all matchup that will determine the path of the NFC playoffs. The league on Sunday night announced the Week 18 schedule, which will wrap up with the hosting the for the NFC North title and the No. 1 seed in the NFC playoffs. The Lions (13-2), who still must play Monday night against the , beat the Vikings (14-2) in , but the rematch will determine the all-important home-field advantage and first-round bye, with the loser being bumped all the way to the No. 5 seed. Saturday will also resolve the AFC North crown, with the hosting the in the afternoon and the , for a wild-card spot, taking on the . Here's the full schedule: Saturday, Jan. 4 Cleveland Browns at Baltimore Ravens, 4:30 p.m. ET, ABC/ESPN Cincinnati Bengals at Pittsburgh Steelers, 8 p.m. ET, ABC/ESPN Sunday, Jan. 5 New York Giants at Philadelphia Eagles, 1 p.m. ET, CBS Buffalo Bills at New England Patriots, 1 p.m. ET, CBS Houston Texans at Tennessee Titans, 1 p.m. ET, CBS Carolina Panthers at Atlanta Falcons, 1 p.m. ET, CBS Washington Commanders at Dallas Cowboys, 1 p.m. ET, FOX Chicago Bears at Green Bay Packers, 1 p.m. ET, FOX Jacksonville Jaguars at Indianapolis Colts, 1 p.m. ET, FOX New Orleans Saints at Tampa Bay Buccaneers, 1 p.m. ET, FOX Kansas City Chiefs at Denver Broncos, 4:25 p.m. ET, CBS Los Angeles Chargers at Las Vegas Raiders, 4:25 p.m., CBS Miami Dolphins at New York Jets, 4:25 p.m., CBS San Francisco 49ers at Arizona Cardinals, 4:25 p.m., CBS Seattle Seahawks at Los Angeles Rams, 4:25 p.m., CBS Minnesota Vikings at Detroit Lions, 8:20 p.m. ET, NBCMomentum Stock AppLovin Tumbles After Getting RejectedFollowing a scintillating showdown between the Washington Commanders and the Atlanta Falcons that determined a spot in the playoffs, Commanders special teams ace Jeremy Reaves had an extra special post-game moment. The talented special teams player proposed to his girlfriend, getting engaged after the game. “Somebody got engaged. Jeremy Reaves, who played 22 special teams snaps, has the most special one of all,” said Mike Tirico on the Sunday Night Football broadcast. “Take a knee at the end of the game for victory, there you go. Jeremy Reaves getting engaged here after the game. Of course she said yes, you’re in the playoffs now. Congratulations!” Check it out below. A special night gets even more special: The Commanders clinched the playoffs tonight and shortly after, Jeremy Reaves proposed to his girlfriend, Mikaela Worley. pic.twitter.com/QdzSi6B85i On3 will have more on this developing story shortly. This article first appeared on 5 GOATs and was syndicated with permission.
Fresh off its biggest win of the season, Penn State plays its first true road game Tuesday when it visits Rutgers in Piscataway, N.J. Aces will be wild for the Nittany Lions (8-1, 1-0 Big Ten) and the Scarlet Knights (5-4, 0-1) as Penn State's Ace Baldwin Jr. will square off against Ace Bailey of Rutgers. Javascript is required for you to be able to read premium content. Please enable it in your browser settings. Stacker compiled a list of the counties with the highest unemployment in Georgia using data from the Bureau of Labor Statistics. Counties are ranked by unemployment rate in October. Click for more. Counties with the highest unemployment in GeorgiaAs the world celebrates Christmas, the chairman of the Economic and Financial Crimes Commission (EFCC), Mr Ola Olukoyede, has expressed hopes of a more significant and better Nigeria shorn of economic and financial crimes and other acts of corruption. He stated this in Abuja on Tuesday, December 24, 2024, while congratulating Christians as they mark the birth of Jesus Christ. EFCC spokesperson Dele Oyewale said in a statement that the EFCC’s boss stressed that the light, joy, hope, truth and liberty Christ brought to the world are significant drives towards zero tolerance for corruption and reform-minded pursuits. He says, “I deeply believe in our nation’s prospects for growth and development. The Christmas season is an opportunity to activate these possibilities. The values of light, joy, hope, truth, and liberty Christ brought to the whole world are significant pathways to integrity and zero tolerance for corruption. We can make Nigeria greater if we embrace these values.” He expressed appreciation to President Bola Tinubu for demonstrating stronger political will in favour of anti-graft efforts, pointing out that the EFCC’s achievements in the last one and a half years are a direct outcome of his courageous and inspirational leadership. “Nigerians can see clearly that President Bola Ahmed Tinubu is bent on tackling corrupt practices. The strides of the EFCC could not have been possible without his active support and courage. We appreciate this at all times”, he said Olukoyede expressed his appreciation to the Judiciary, stressing that the “professionalism, commitment, integrity, and courage of our justices and judges are significantly strengthening the EFCC in its anti-corruption work. ” He charged the judiciary to continue on its path of redemption and equity.Haiti gang attack on journalists covering hospital reopening leaves 2 dead, several wounded
Best TV of 2024: A modestly better lineup than usual, but why didn’t it feel that way?Caitlin Clark honored as AP Female Athlete of the Year following her impact on women's sports Caitlin Clark has been named the AP Female Athlete of the Year after raising the profile of women’s basketball to unprecedented levels in both college and the WNBA. She led Iowa to the national championship game, was the top pick in the WNBA draft and captured rookie of the year honors in the league. Fans packed sold-out arenas and millions of television viewers followed her journey on and off the court. Clark's exploits also put other women's sports leagues in the spotlight. A group of 74 sports journalists from AP and its members voted on the award. Other athletes who received votes included Olympic gold medalist Simone Biles and boxer Imane Khelif. Clark’s only the fourth women’s basketball player to win the award since it was first given in 1931. Wemby at The Garden. LeBron vs. Steph. The NBA's Christmas Day lineup, as always, has star power LeBron James made his Christmas debut in 2003. Victor Wembanyama was born 10 days later. That’s right: James has been featured on the NBA’s big day for longer than Wembanyama has been alive. And on Wednesday the league’s oldest player and brightest young star will be big parts of the holiday showcase. It’s another Christmas quintupleheader, with Wembanyama and the San Antonio Spurs visiting the New York Knicks, Minnesota going to Dallas for a Western Conference finals rematch, Philadelphia heading to Boston to renew a storied rivalry, James and the Los Angeles Lakers taking on Stephen Curry and the Golden State Warriors, and Denver playing at Phoenix. Pro Picks: Chiefs will beat the Steelers and Ravens will edge the Texans on Christmas Day Playoff berths, draft positioning and more are up for grabs in Week 17. There’s going to be plenty of football on television this holiday week with the NFL playing games on five out of six days, starting with a doubleheader on Christmas Day featuring four of the AFC’s top five teams. Patrick Mahomes and the two-time defending Super Bowl champion Kansas City Chiefs visit Russell Wilson and the Pittsburgh Steelers on Wednesday. Then, two-time NFL MVP Lamar Jackson and the Baltimore Ravens take on C.J. Stroud and the Houston Texans. The Bears host the Seahawks on Thursday night and there are three games on Saturday, making Sunday’s schedule light at nine games. Falcons drafting Penix no longer a head-scratcher with rookie QB shining in place of benched Cousins It was the most surprising first-round pick in a long time when the Atlanta Falcons chose Michael Penix Jr. with the eighth overall selection in the NFL draft last April. That came just six weeks after the Falcons had signed free agent quarterback Kirk Cousins to a four-year, $180 million deal with $100 million in guarantees. But that move is no longer a head-scratcher after Penix's solid starting debut in place of a benched and turnover-prone Cousins. Several teams have fared well with new quarterbacks this season including the Steelers, Broncos, Vikings and Commanders. Lindsey Vonn thinks her new titanium knee could start a trend in skiing. And pro sports in general ST. MORITZ, Switzerland (AP) — Lindsey Vonn thinks her new titanium knee could be the start of a trend in ski racing. The 40-year-old American standout had replacement surgery in April and returned to the World Cup circuit after nearly six years last weekend. She says her knee feels “amazing" and that "it’s something to seriously consider for athletes that have a lot of knee problems.” Her surgery was the first of its kind in World Cup skiing. Vonn had a robot-assisted surgery in April with part of the bone in her right knee cut off and replaced by two titanium pieces. She was planning her comeback a month later. Boise State's legacy includes winning coaches and championship moments No. 8 and third-seeded Boise State is preparing for its third trip to the Fiesta Bowl. This time it's in a playoff quarterfinal against No. 5 and sixth-seeded Penn State on New Year’s Eve. Boise State's first appearance on the national stage was in a memorable victory over Oklahoma in the Fiesta Bowl on Jan. 1, 2007. But former coach Chris Petersen said the victory in that bowl three years later over TCU was even more meaningful for the program. Players have mixed feelings about being on the road on Christmas as NFL adds more holiday games OWINGS MILLS, Md. (AP) — Games on Christmas aren’t new to the NFL. The Miami Dolphins famously beat the Kansas City Chiefs in a playoff game on Dec. 25, 1971 — a double-overtime classic that still holds the record for the NFL’s longest game. In 2020, New Orleans running back Alvin Kamara tied an NFL record with six touchdowns in a game when the Saints beat Minnesota on Christmas. Lately the league has been much more aggressive about scheduling games on Christmas. That's been met with mixed feelings among the players. Baltimore tackle Ronnie Stanley says there is an offensive line Christmas party planned for Friday at center Tyler Linderbaum’s house. Quarterback Lamar Jackson’s plan is to celebrate on Thursday. Embiid ejected after drawing 2 technicals in game against Wembanyama and Spurs PHILADELPHIA (AP) — Philadelphia 76ers star Joel Embiid was ejected in the first half of Monday night’s game against San Antonio after drawing two technical fouls. Referee Jenna Schroeder ejected Embiid with 2 minutes, 59 seconds left in the second quarter. The seven-time All-Star received the first technical for arguing with Schroeder, and received another technical — and ejection — from Schroeder before any more game time elapsed. Embiid was close to Schroeder, but it wasn’t clear from replays whether he made contact with the official. An enraged Embiid charged toward the officials after the ejection and was restrained by teammate Kyle Lowry, head coach Nick Nurse and several assistants. Nikki Glaser uses Prime Video's NFL postgame show appearances to help prepare for Golden Globes INGLEWOOD, Calif. (AP) — Nikki Glaser has become a familiar face to football fans this season. Her breakthrough performance at the Tom Brady Roast on May 5 paved the way for five appearances on Amazon Prime Video’s “Thursday Night Football” postgame show. Glaser said before last Thursday’s game between the Denver Broncos and Los Angeles Chargers that doing her “Late Hits” segment was a no-brainer following her success at the Brady roast. Leaving Thunder, Bucks off the NBA's Christmas game list has those teams feeling snubbed Oklahoma City leads the Western Conference and has a MVP candidate in Shai Gilgeous-Alexander. Milwaukee has the NBA’s leading scorer in Giannis Antetokounmpo. They were the teams that made their way to the NBA Cup final. By any measure, they’re both very good teams. And neither will play on Christmas Day this year. Bah, humbug. The NBA faces the same challenge every summer, figuring out which 10 teams will get the honor of playing on Christmas Day. But the Bucks and Thunder are right to feel snubbed.Scanlan: Time for legislators to protect womenBiden will decide on US Steel acquisition after influential panel fails to reach consensus WASHINGTON (AP) — A powerful government panel has failed to reach consensus on the possible national security risks of a nearly $15 billion proposed deal for Nippon Steel of Japan to purchase U.S. Steel. The Committee on Foreign Investment in the United States on Monday sent its long-awaited report to President Joe Biden, a longtime opponent of the deal. Some federal agencies represented on the panel were skeptical that allowing a Japanese company to buy an American-owned steelmaker would create national security risks. That's according to a U.S. official familiar with the matter. Both Biden and President-elect Donald Trump opposed the merger and vowed to block it. Nippon Steel says it is confident the deal will go ahead. Nissan and Honda to attempt a merger that would create the world's No. 3 automaker TOKYO (AP) — Japanese automakers Nissan and Honda have announced plans to work toward a merger that would catapult them to a top position in an industry in the midst of tectonic shifts as it transitions away from its reliance on fossil fuels. The two companies said they signed an agreement on integrating their businesses on Monday. Smaller Nissan alliance member Mitsubishi Motors agreed to join the talks. News of a possible merger surfaced earlier this month. Japanese automakers face a strong challenge from their Chinese rivals and Tesla as they make inroads into markets at home and abroad. What a merger between Nissan and Honda means for the automakers and the industry BANGKOK (AP) — Japanese automakers Honda and Nissan will attempt to merge and create the world’s third-largest automaker by sales as the industry undergoes dramatic changes in its transition away from fossil fuels. The two companies said they had signed a memorandum of understanding on Monday and that smaller Nissan alliance member Mitsubishi Motors also had agreed to join the talks on integrating their businesses. Honda will initially lead the new management, retaining the principles and brands of each company. Following is a quick look at what a combined Honda and Nissan would mean for the companies, and for the auto industry. Survey: Small businesses are feeling more optimistic about the economy after the election A survey shows small business owners are feeling more optimistic about the economy following the election. The National Federation of Independent Businesses’ Small Business Optimism Index rose by eight points in November to 101.7, its highest reading since June 2021. The Uncertainty Index declined 12 points in November to 98, following October’s pre-election record high of 110. NFIB Chief Economist Bill Dunkelberg said small business owners became more certain about future business conditions following the presidential election, breaking a nearly three-year streak of record high uncertainty. The survey also showed that more owners are also hoping 2025 will be a good time to grow. Heavy travel day starts with brief grounding of all American Airlines flights WASHINGTON (AP) — American Airlines briefly grounded flights nationwide due to a technical problem just as the Christmas travel season kicked into overdrive and winter weather threatened more potential problems for those planning to fly or drive. Government regulators cleared American flights to get airborne Tuesday about an hour after the Federal Aviation Administration ordered a national ground stop, which prevented planes from taking off. American said in an email that the problem was caused by vendor technology in its flight operating system. Aviation analytics company Cirium said flights were delayed across American’s major hubs, with only 37% leaving on time. Nineteen flights were cancelled. Nordstrom to be acquired by Nordstrom family and a Mexican retail group in $6.25 billion deal Century-old department store Nordstrom has agreed to be acquired and taken private by Nordstrom family members and a Mexican retail group in a $6.25 billion deal. Nordstrom shareholders will receive $24.25 in cash for each share of Nordstrom common stock, representing a 42% premium on the company’s stock as of March 18. Nordstrom’s board of directors unanimously approved the the proposed transaction, while Erik and Pete Nordstrom — part of the Nordstrom family taking over the company — recused themselves from voting. Following the close of the transaction, the Nordstrom Family will have a majority ownership stake in the company. Stock market today: Wall Street rallies ahead of Christmas Stocks closed higher on Wall Street ahead of the Christmas holiday, led by gains in Big Tech stocks. The S&P 500 added 1.1% Tuesday. Trading closed early ahead of the holiday. Tech companies including Apple, Amazon and chip company Broadcom helped pull the market higher. The Dow Jones Industrial Average rose 0.9%, and the Nasdaq composite climbed 1.3%. American Airlines shook off an early loss and ended mostly higher after the airline briefly grounded flights nationwide due to a technical issue. Treasury yields held steady in the bond market. The yield on the 10-year Treasury was little changed at 4.59% An analyst looks ahead to how the US economy might fare under Trump WASHINGTON (AP) — President-elect Donald Trump won a return to the White House in part by promising big changes in economic policy — more tax cuts, huge tariffs on imports, mass deportations of immigrants working in the United States illegally. In some ways, his victory marked a repudiation of President Joe Biden’s economic stewardship and a protest against inflation. It came despite low unemployment and steady growth under the Biden administration. What lies ahead for the economy under Trump? Paul Ashworth of Capital Economics spoke recently to The Associated Press. The interview has been edited for length and clarity. American consumers feeling less confident in December, Conference Board says American consumers are feeling less confident in December, a business research group says. The Conference Board said Monday that its consumer confidence index fell back in December to 104.7 from 112.8 in November. Consumers had been feeling increasingly confident in recent months. The consumer confidence index measures both Americans’ assessment of current economic conditions and their outlook for the next six months. The measure of Americans’ short-term expectations for income, business and the job market tumbled more than a dozen points to 81.1. The Conference Board says a reading under 80 can signal a potential recession in the near future. Stock market today: Wall Street rises at the start of a holiday-shortened week Stocks closed higher on Wall Street at the start of a holiday-shortened week. The S&P 500 rose 0.7% Monday. Several big technology companies helped support the gains, including chip companies Nvidia and Broadcom. The Dow Jones Industrial Average added 0.2%, and the Nasdaq composite rose 1%. Honda's U.S.-listed shares rose sharply after the company said it was in talks about a combination with Nissan in a deal that could also include Mitsubishi Motors. Eli Lilly rose after announcing that regulators approved Zepbound as the first prescription medicine for adults with sleep apnea. Treasury yields rose in the bond market.
Jimmy Carter, Oldest Former US President Ever, Dies at 100Struggling Syracuse looks to climb back above .500 when it hosts Albany on Tuesday night. The Orange (4-4) are coming off a conference loss to Notre Dame where they failed to make a 3-pointer in a game for the first time in more than 10 years, going 0-for-9 from behind the arc. They will be without leading scorer J.J. Starling, who broke his hand in practice last Monday. Orange coach Adrian Autry said there was "no timetable" for Starling's return after the loss to the Fighting Irish and lamented his team's struggles with turnovers and free-throw shooting in the defeat. "Too many blown opportunities," Autry said. "We're not shooting the ball well. We have to adjust and go game by game now. Our front court has been pretty secure, but we have to keep working and getting better." Starling was averaging a team-high 19.8 points before his injury. The Orange may need to lean more on freshman Donnie Freeman, who has been a standout for Syracuse this season. He's averaging 12.8 points and 8.8 rebounds and already has four double-doubles. He was co-ACC Rookie of the Week last week. Defensively, the Orange have struggled. They rank No. 329 in scoring defense, giving up 79.4 points per game. Albany is scoring 77.2 ppg so far this season. The Great Danes (6-4) were downed by Boston University 80-74 in overtime on Saturday. They started the season 5-1 but have lost three of their last four. Senior guard Byron Joshua, a transfer from Alcorn State, is the Great Danes' leading scorer at 13.6 ppg. Amar'e Marshall was an All-America East Conference pick last season after averaging 16.7 points, but his field goal shooting has dropped from 43.4 percent last season to 34.5 percent this season. He is scoring 11.7 ppg. "I think we're learning how to compete at the right level," Albany coach Dwyane Killings said after a loss to Georgetown on Nov. 30. "I think the one thing that troubles us a lot is that our identity and our energy comes when the ball goes in the basket. When it doesn't, I don't think we have the grit that we need right now." Albany has been one of the best teams in the country in terms of steals. The Great Danes average 10.2 steals per game, which is tied for No. 12 in the nation. Syracuse is 8-0 against Albany all-time with the teams last meeting in 2011. Syracuse is 4-0 at home and 4-0 against non-power-conference opponents. --Field Level Media