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India To Host 'World Audio Visual Entertainment Summit' For First Time: PM ModiNoneEven experienced drivers can be forgiven for missing a roundabout exit once or twice, but a disoriented robotaxi in Arizona did it 36 times... in a row. While Waymo taxis are among the most advanced autonomous vehicles on the road today, in a video on X, a confused AV appears to be quite literally stuck in a loop. (Waymo clarified there was the high-tech merry-go-round.) And yet, even with blunders like these, there were more vehicles driving themselves this year than ever before. Once cordoned off to a few test tracks and small patches of land in Mountain View, AVs are now rearing their sensors-flapping heads in . Tens of millions of drivers, cyclists, and pedestrians are learning how to coexist amongst these machines while their shared roads serve as real-world test-beds for full-scale AV deployment. Sure, it’s not , but 2024 was the year driverless cars hit their stride and flooded the streets–in other words, ready or not, they got real. Whether or not that’s a good thing depends entirely on who you ask. Several computer science experts and civil engineers told that they were confident these early autonomous vehicles (AV’s), slow and as they might seem sometimes, are the harbingers of a near-future marked by considerably less deadly damage caused by distracted humans. Others, were less optimistic. The actual of these cars in 2024 remains a . One thing seems certain: the AV race is on. Though many companies have faded, , a handful of major players like Alphabet’s Waymo, Amazon-backed Zoox, and Aurora are bulking up and scaling up operations. In the process, they are changing the way millions of people interact on the road. And it’s just getting started. Though this proliferation of AVs can feel sudden to the average person, Carnegie Mellon University Professor Ragunathan Rajkumar told the road there was incremental. Rajkumar, who has worked on autonomous research for decades, says the first example of what one could consider a rudimentary autonomous vehicle dates all the way back to 1984 at Carnegie Mellon. Progress in the space leaped forward twenty years later when DARPA, the , held a driverless car competition called the “ ” The teams that won attracted the attention of Google co-founders Larry Page and Sergey Brin. That eventually led to the creation of what would become Waymo and helped turbo charge the current era of privatized driverless car development. “The [2007] competition showed it was actually feasible,” Rajkumar siad. “It made this singular point that autonomous vehicles are only a question of when and not a question of if anymore.” Waymo was not only one of the earliest entries into the space, but also one of the most uniquely suited to make their product commercially available in 2024. Being tied to Google gave Waymo all the technical expertise and crucially, the deep pockets it needed to slowly build up its testing apparatus over the course of several years without a pressing need for an immediate return on investment. The company started in relatively sparse, Arizona suburbs and has gradually built up to more complex environments over time. Rajkumar said this approach differs from competitors like GM-backed Cruise which started later and may have tried to rush over some steps in a race to make a commercially viable product. That and an . By the time they were ready to test again this year, Waymo had already gained too much ground. In other words, slow and steady really does win the race. (GM announced it would absorb Cruise and and towards fully autonomous personal vehicles earlier this month.) 2024 marked a “milestone” in driverless vehicle deployment according to Autonomous Industry Vehicle Association (AIVA) CEO Jeff Farrah. He told that 25 states are now on the policy path towards some AV deployment. These new laws will cover around 56% of the US population. Waymo, after testing for the better part of a decade, in San Francisco, Los Angeles, and Phoenix through its app. As of late October 2024, Waymo said it was every week. Those numbers will balloon further next year when the company begins offering . Waymo isn’t alone either. Zoox— that is working on deploying a purpose-built, bi-direcitonal vehicle with no steering wheel and four seats facing towards each other—is currently testing their fleet in Cruise resumed testing in Dallas, Houston, and Phoenix, earlier this year that saw it lose its license to operate in California. Tesla, which is controversially trying to achieve full autonomy without using LiDAR technology, charted out plans to begin production of a “ ” robotaxis service sometime before 2027. Taxi-style ride hailing services also aren’t the only types of self-driving vehicles already filling US roads. Mercedes-Benz, last year, , a SAE Level 3 system that lets drivers legally operate a vehicle up to 40mph hands free and without their eyes facing the road. Aurora, a company , has been conducting self-driving tests (with a human safety driver present) in Texas for several years. The company to let trucks drive free of human operators in the state next year. “It’s clear that AVs are here to stay and as more consumers experience them, the data shows they are enjoying their experience,” Farrah told For cities like San Francisco and Austin, Texas where are making their way around town at any given time, the presence of cars without a human driver has gone from novel to common. Though they once regularly solicited gawking pedestrians and yells from angry pickup drivers, AVs in 2024 increasingly blend into the urban traffic. That seeming sense of normalcy on the ground runs counter to broader snapshots of American sentiment. Only 37% of US adults said they would want to ride in a driverless vehicle. And yet, in places where driverless options are actually available, early reports show some riders are being won over. Part of that acceptance may be due to their passive behavior. “They [robotaxis] tend to drive very cautiously,” University of Texas Professor of Transportation Engineering Kara Kockelman told “They look and feel much less dangerous than other vehicles driven by 19-year-olds who want a speed rush.” Nicole Moore, the President of Rideshare Drivers United and herself a part-time Lyft driver had another way of describing them: “It’s slow, stoned driving,” Moore told Proponents of autonomous vehicles say the billions of dollars and investment and countless hours of testing are in the service of two main overarching goals: safety and convenience. On safety, experts told a world awash with AVs could meaningfully cut down on the in the US every year. Globally, around 1.3 million people die every year in auto accidents. Kockelman, who has conducted academic research on the cost-benefit analysis of AV fleets on public roads, said she expects driverless tech to potentially cut down on 80-85% of costs associated with auto crashes, a figure she puts close to $1 trillion. That’s not counting other non-economic costs resulting from crashes too like pricey doctors’ visits and long-lasting mental and emotional scars. A conducted by Waymo and insurer Swiss Re analyzing insurance claims data found Waymo vehicles resulted in less property damages and fewer injuries than human drivers. Aside from the safety argument, Rajkumar said he was optimistic AVs would also empower legally blind individuals and others with physical disabilities to have greater degrees of mobility and autonomy. For others, time spent saved from focusing on driving could be spent completing a meeting, speaking with family, or simply taking a nap. “The arc of the progress has been happening,” Rajkumar said. Maybe. But that vision wasn’t what was on offer in 2024. It doesn’t take long scrolling through social media to find shocking examples of supposedly advanced autonomous vehicles appearing undeniably stupid. There’s these accounts of Cruise driverless vehicles causing traffic jams in and . In other cases, a fleet of recharging Waymo vehicles at each other, much to the annoyance of nearby apartment residents trying to sleep. A Cruise vehicle operating in San Francisco last year drove into a city paving project and . In Austin, a server at a local taco shop told this reporter about a recent case of a Waymo seemingly getting trapped in the restaurant’s parking lot, apparently mistaking it for a side-street. “Everyone went outside and started clapping when it drove away,” he said. But there are more serious concerns as well. For starters, research looking into the limited test cases of AVs currently operating on public roads hasn’t met the high-bar set by some of the tech’s most vocal boosters. A recent conducted by researchers from George Mason and Duke University concluded many areas of improvement were needed. The paper, which compared crash reporting data from AVs and human drivers, claims AV computer vision systems were at times “very brittle” and can “play an outsized role in crashes. In some notable cases, self-driving vehicles were more likely to be involved in accidents than humans. The self-driving vehicles reviewed were struck from behind at a rate 1.7 times higher than human drivers. And while AV-makers often blame these incidents on other distracted human drivers, the researchers say AV can surprisingly decelerate or slam on the brakes “for no obvious reason.” The researchers also noted a “substantial” number of crashes that occurred from AVs seemingly unable to properly understand social norms around driving. Those issues can lead to tragedies when scaled up. In 2018, the first reported human death linked to an autonomous vehicle occurred when an Uber self-driving car crossing a road in Temple, Arizona. An found the vehicle’s software wasn’t prepared to expect pedestrians crossing streets outside of crosswalks. Last year, a Cruise vehicle collided with and then dragged a pedestrian for 20 feet. Experts told the brutal dragging incident, which contributed to Crusie losing its license to operate in California, was likely the result of the company failing to include sensors underneath its vehicle. Though fully-autonomous vehicles like those operated by Waymo and Zoox haven’t resulted in human fatalities thus far, they also mostly aren’t yet operating on more dangerous highway speeds. This year, just as more AVs were filling US roads, the National Highway Traffic Administration (NHTSA) over allegations their vehicles had “potentially violated traffic safety laws.” A Waymo Spokesperon told it currently provides 150,000 paid trips. Weekly “in some of the most challenging and complex environments.” “We are proud of our performance and safety record over tens of millions of autonomous miles driven, as well as our demonstrated commitment to safety transparency,” the spokesperson said. “NHTSA plays a very important role in road safety and we will continue to work with them as part of our mission to become the world’s most trusted driver.” There’s also the still unresolved question of what happens to the more than one million human and Uber Lyft drivers who are increasingly finding themselves in competition with driverless cars. Moore, the Lyft driver and Rideshare Drivers United President says she has watched as AVs have proliferated around her in Los Angeles. In the past, her and other drivers would share videos of the cars getting stuck or malfunctioning for a quick laugh. But recently, Moore says she saw a Waymo vehicle pick up a passenger and suddenly had a realization. “Oh my god,” she recalls. “That [Waymo] is driving somebody that I could be taking!” That’s a thought many more gig workers may have to come to terms with in the months and years to follow. Uber, the leading ride-hailing service, has plans to let riders request Waymo vehicles from its app in Austin and Atlanta next year. And while Waymo’s still slightly more expensive options and have limited routes, that may soon change. Kockelman and Rajkumar agreed robottaxis may become more appealing to riders but they noted it would likely take time before they mean guly chip away at human gig-worker number. Human drivers will still be needed for the immediate future to operate in inclement weather and high speed situations. Even in markets where robotaxis proliferate, ride-share companies may still rely on humans to meet rider demands during peak periods. “It’s going to be a slow rollout just like electric vehicles,” Kockelman said. Those words aren’t all that reassuring for professional drivers like Moore. “Every Waymo that people get into is costing a driver. There’s no doubt about that,” she said. “It’s the same market. This is the wild, wild west of deregulated transportation.” And while 2024 saw the realization of driverless vehicles for many, it also previewed a brewing backlash from an impassioned minority. Waymo is currently suing a San Francisco man prosecutors alleged was between June 24 and June 26, sometimes with riders present. The slashing incidents came several months after a crowd of people, also in San Francisco, , and ultimately set it ablaze. People in the crowd cheered and posed for photographs next to the burning wreckage. Anti-driverless car activists previously to trick AV sensors and temporarily disable them. Farrah of the AVIA said driverless vehicles are at an “inflection point” in the US. As more states allow them to operate on public roads, there may be increased pressure for new federal legislation mandating a set of standards. Driverless vehicles are present in numerous cities but actually having one drive across the country would be a legal nightmare. Companies like Waymo and Zoox meanwhile, which have had years of generous coddling from wealthy investors to train up their fleets, may increasingly feel pressure to make their products financially viable. 2024 may have been the year driverless cars became “real” for many Ameircans, but 2025 will be the year we find out just how disruptive, both positively and negatively, this technology may really wind up being. And while that transformation can feel gradual in the moment, it can also snowball in what feels like an instant. “The technology is going to take a while to develop, but when you think about it, AI just popped out and all of a sudden it was there,” Moore said. “We’re dealing with a pop-out [moment] here.”
What happens next with Alex Jones' Infowars? No certainty yet after sale to The Onion is rejected
President-elect Donald Trump's repeated support for TikTok has sparked speculation about potential solutions to prevent the app's impending ban in the United States, though the path forward remains unclear. "We got to keep this sucker around for a little while," Trump told supporters on Sunday, just days after meeting with TikTok CEO Shou Zi Chew in Florida. Trump, who credits the wildly popular platform with delivering him a large young user base, opposes banning TikTok partly because he believes it would primarily benefit Meta, the Mark Zuckerberg-led company behind Instagram and Facebook. The situation is complex, according to University of Richmond School of Law professor Carl Tobias, given the various potential solutions and Trump's unpredictable nature. Congress overwhelmingly passed legislation, signed by President Joe Biden in April, that would block TikTok from US app stores and web hosting services unless Beijing-based ByteDance sells its stake by January 19. US officials and lawmakers grew wary of the potential for the Chinese government to influence ByteDance or access the data of TikTok's American users. Even with Trump's decisive election victory and incoming Republican-led Congress, acquiescing to the president-elect's desire and preventing the ban faces significant hurdles. The law enjoyed rare bipartisan support in a divided Washington, making its outright repeal through a vote in Congress politically unlikely even with Trump's influence over Republicans. The Supreme Court may offer the clearest path forward. TikTok has appealed to the nation's highest court, arguing the law violates First Amendment rights to free speech. The court, which is dominated by Trump-aligned conservatives, will hear the case on January 10, just nine days before the ban takes effect. This follows a lower appeals court's unanimous decision to uphold the law in December. Another possibility, according to Tobias, is that a Trump-led Department of Justice could determine ByteDance has addressed the law's national security concerns. However, such a move would likely be seen as caving to China by Congress and others. The final option is ByteDance selling to a non-Chinese buyer, though the company has consistently refused this possibility. With 170 million monthly active users, acquiring TikTok's US operations would require substantial resources. As president, Trump could extend the ban deadline by 90 days to facilitate a transaction. Few potential buyers have emerged, with major tech companies likely deterred by antitrust concerns. Former Trump Treasury secretary Steve Mnuchin, who runs a private equity fund backed by Japan's SoftBank Group and Abu Dhabi's Mubadala sovereign wealth fund, has expressed interest. During a recent event with Trump, SoftBank CEO Masayoshi Son pledged to invest $100 billion in the US economy, though specific investments weren't detailed. Other contenders include US real estate billionaire Frank McCourt, who aims to make social media safer through his Project Liberty organization. Elon Musk, given his proximity to Trump and ownership of X, could also have a role to play, as he has expressed plans to transform the text-focused platform into something more like TikTok. A senior Republican lawmaker recently suggested Trump might orchestrate a "deal of the century" satisfying both US concerns and ByteDance's interests. The chairman of the US House committee on China, John Moolenaar, told Fox News Digital that once ByteDance accepts it must comply with US law, the situation could progress rapidly. Any agreement would need Beijing's approval, with US-China relations expected to remain tense during Trump's upcoming term. This isn't the first attempt to resolve TikTok's US status. In 2020, Trump also threatened a ban unless ByteDance sold its US operations. While Oracle and Walmart reached a preliminary agreement with ByteDance for ownership stakes, legal challenges and the transition to the Biden administration prevented the deal's completion. arp/mlm(TNS) — New Internet rules for Baton Rouge students and employees were approved Thursday, but only after the removal of a few provisions that , including a broad restriction on taking and sharing photos and videos. Also removed were limits on which search engines can be used on the district network and a ban on students and employees from using personal hot spots and virtual private networks (VPN) when they are not connected to the district network. The East Baton Rouge (EBR) Parish School Board on Thursday voted unanimously to approve the new policy. Board member Nathan Rust had previously questioned the wisdom of restricting search engines. Board Vice President Patrick Martin V also had questioned language barring the "taking photos and/or videos" of students and employees and then sharing them. The prior approval of search engines was subsequently removed; now, unspecified "Internet tools" need to be approved in advance. The bar on taking photos and videos that Martin questioned was modified to apply when students use "any EBR device" to take "unauthorized" photos and videos. The restrictions on sharing photos and videos expand on a long-standing rule that students and employees can't "distribute private information about themselves or others." The district's "Internet Safety and Network Use" policy was last updated in 2012. Much of the new language references technology such as artificial intelligence (AI) and cloud-based computing that was rare or nonexistent 12 years ago. The revisions were suggested by an in-house committee that met this spring and included teachers, school leaders, department heads and technology staff. In 2022, East Baton Rouge floated but later withdrew a controversial policy that would have set new limits on employees and how they use social media outside of school. This school year, Louisiana instituted a new law requiring students to turn off and stow away their phones during the school day. Computer use in schools has grown substantially in the past 12 years. In 2016, East Baton Rouge became a "one-to-one" district in most grades, meaning that every student in those grades received a Chromebook. Those computers have been in heavy use since, particularly when students routinely used them at home during the COVID pandemic. Initially, a proposed policy change was to have students now responsible for "the care and maintenance of any EBR device assigned to them." The final version approved Thursday changed the word "maintenance" to "preservation." Students who act irresponsibly with Chromebooks and other school-issued devices already face potential discipline or fines if they "willfully" damage such a device. In a nod to recent scandals where students and adults had inappropriate relations, one new provision specifies that school employees are not to use district resources or devices to "communicate directly with students unless via a method authorized by the district." AI tools such as Chat GPT would face new restrictions. Students could use them only if they are approved, and they would need to cite their AI use in instances where copyright law might come into play. They also could not use AI to commit crimes or violate codes of conduct.The Latest: Police search for man who killed UnitedHealthcare CEO, new photos of suspect released
METAIRIE, La. (AP) — If Saints interim coach Darren Rizzi has any definite ideas about who'll play quarterback for New Orleans against Washington on Sunday, he's not ready to share that information. Rizzi maintained on Wednesday that there's still a chance that Derek Carr could clear the concussion protocol and function well enough with his injured, non-throwing left hand to return against the Commanders. Meanwhile, reserve QBs Jake Haener and Spencer Rattler split first-team snaps during Wednesday's practice, which Carr missed, Rizzi said. “We're not going to name a starter right now,” said Rizzi, who also made a point of noting that Carr would not be placed on the club's injured reserve list and would not need surgery. “We're going to see how that progression plays out, first with Derek and then obviously with Jake and Spencer.” Carr, whose latest injury occurred when he tried to dive for a first down during Sunday's 14-11 victory over the New York Giants , has already missed three starts this season because of a separate, oblique injury. New Orleans lost all three of those games, with Rattler, a rookie, starting and Haener, a second-year pro, serving as the backup. In his three starts, Rattler completed 59 of 99 passes (59.6%) for 571 yards, one TD and two interceptions. Haener has gotten sporadic work this season in relief of both Carr and Rattler, completing 14 of 29 passes (48.3%) for 177 yards and one TD without an interception. Rizzi said he finds the 6-foot-1 Haener and 6-foot Rattler “very similar in a lot of ways," adding that whichever of those two might play “doesn't change a whole bunch" in terms of game-planning. “They're both similar-size guys. Their athletic ability is very similar,” Rizzi said. “They're similar-style quarterbacks. We're not dealing with opposites on the spectrum.” The Saints also signed another QB this week — Ben DiNucci — to help take scout team snaps at practice, now that Rattler and Haener are not as available to do that while competing to possibly start if Carr is indeed unable to play. The Saints (5-8) have won three of four games since Rizzi took over following the firing of coach Dennis Allen. That allowed New Orleans to remain alive in the NFC South Division, currently led by Tampa Bay (7-6). Rizzi said Carr has not had any setbacks this week in terms of progressing through the NFL's concussion protocol. “By the end of the week, if's he's not able to get any reps in any form or fashion, then obviously we'll go with one of the other guys,” Rizzi said. NOTES: RB Alvin Kamara did not practice on Wednesday because of an illness. ... WR Chris Olave, who is out indefinitely because of concussions this season, has returned to meetings at Saints headquarters. He as not, however, made plans to return to practice yet because he still plans to meet first with neurological specialists to try to assess the risks of returning to action during what's left of this season. Rizzi said the possibility of Olave playing again this season remains “on the table” for now. AP NFL: https://apnews.com/hub/NFL
LA PAZ COUNTY, Ariz. — The remains of a man reported missing earlier this year were recently located in western Arizona. La Paz County officials said human remains were located on Nov. 9 in the desert area near Bouse and DNA testing identified the remains as belonging to Chris Sins. Sins, 34, was reported missing on July 22 after he was last seen in the desert southeast of Bouse. A vehicle he was in had gotten stuck, resulting in Sins and a friend walking and separating from each other along the way. Several coordinated searches were conducted in the following weeks and yielded no results, the sheriff's office said. A shoe was recovered by hunters on Nov. 4 about 1,500 feet from where the remains were later located. RELATED: Glendale police asking for the public's help after missing Phoenix man is found dead RELATED: Brothers who were previously missing now located, authorities say Watch 12News for free You can now watch 12News content anytime, anywhere thanks to the 12+ app! The free 12+ app from 12News lets users stream live events — including daily newscasts like "Today in AZ" and "12 News" and our daily lifestyle program, "Arizona Midday"—on Roku, Apple TV and Amazon Fire TV . 12+ showcases live video throughout the day for breaking news, local news, weather and even an occasional moment of Zen showcasing breathtaking sights from across Arizona. Users can also watch on-demand videos of top stories, local politics, I-Team investigations, Arizona-specific features and vintage videos from the 12News archives. Roku : Add the channel from the Roku store or by searching for "12 News KPNX." Amazon Fire TV : Search for "12 News KPNX" to find the free 12+ app to add to your account , or have the 12+ app delivered directly to your Amazon Fire TV through Amazon.com or the Amazon app.Landsea Homes Corp shareholder Chen Huaijun sells $42 million in stock
The large mysterious drones reported flying over parts of New Jersey in recent weeks appear to avoid detection by traditional methods such as helicopter and radio, according to a state lawmaker briefed Wednesday by the Department of Homeland Security. In a post on the social media platform X, Assemblywoman Dawn Fantasia described the drones as up to 6 feet in diameter and sometimes traveling with their lights switched off. The Morris County Republican was among several state and local lawmakers who met with state police and Homeland Security officials to discuss the spate of sightings that range from the New York City area through New Jersey and westward into parts of Pennsylvania, including over Philadelphia. The devices do not appear to be The dronees wereffffflown by hobbyists, Fantasia wrote. Dozens of mysterious nighttime flights started last month and have raised growing concern among residents and officials. Part of the worry stems from the flying objects initially being spotted near the Picatinny Arsenal, a U.S. military research and manufacturing facility; and over President-elect Donald Trump’s golf course in Bedminster. Drones are legal in New Jersey for recreational and commercial use, but they are subject to local and Federal Aviation Administration regulations and flight restrictions. Operators must be FAA certified. Most, but not all, of the drones spotted in New Jersey were larger than those typically used by hobbyists. The number of sightings has increased in recent days, though officials say many of the objects seen may have been planes rather than drones. It’s also possible that a single drone has been reported more than once. Gov. Phil Murphy and law enforcement officials have stressed that the drones don’t appear to threaten public safety. The FBI has been investigating and has asked residents to share any videos, photos or other information they may have. Two Republican Jersey Shore-area congressmen, U.S. Reps. Chris Smith and Jeff Van Drew, have called on the military to shoot down the drones. Smith said a Coast Guard commanding officer briefed him on an incident over the weekend in which a dozen drones followed a motorized Coast Guard lifeboat “in close pursuit” near Barnegat Light and Island Beach State Park in Ocean County. Coast Guard Lt. Luke Pinneo told The Associated Press Wednesday “that multiple low-altitude aircraft were observed in vicinity of one of our vessels near Island Beach State Park.” The aircraft weren't perceived as an immediate threat and didn't disrupt operations, Pinneo said. The Coast Guard is assisting the FBI and state agencies in investigating. In a letter to U.S. Defense Secretary Lloyd Austin, Smith called for military help dealing with the drones, noting that Joint Base McGuire-Dix-Lakehurst has the capability "to identify and take down unauthorized unmanned aerial systems.” However, Pentagon spokeswoman Sabrina Singh told reporters Wednesday that “our initial assessment here is that these are not drones or activities coming from a foreign entity or adversary.” Many municipal lawmakers have called for more restrictions on who is entitled to fly the unmanned devices. At least one state lawmaker proposed a temporary ban on drone flights in the state. “This is something we’re taking deadly seriously. I don’t blame people for being frustrated," Murphy said earlier this week. A spokesman for the Democratic governor said he did not attend Wednesday's meeting. Republican Assemblyman Erik Peterson, whose district includes parts of the state where the drones have been reported, said he also attended Wednesday's meeting at a state police facility in West Trenton. The session lasted for about 90 minutes. Peterson said DHS officials were generous with their time, but appeared dismissive of some concerns, saying not all the sightings reported have been confirmed to involve drones. So who or what is behind the flying objects? Where are they coming from? What are they doing? “My understanding is they have no clue,” Peterson said. A message seeking comment was left with the Department of Homeland Security. Most of the drones have been spotted along coastal areas and some were recently reported flying over a large reservoir in Clinton. Sightings also have been reported in neighboring states. James Edwards, of Succasunna, New Jersey, said he has seen a few drones flying over his neighborhood since last month. “It raises concern mainly because there's so much that's unknown,” Edwards said Wednesday. “There are lots of people spouting off about various conspiracies that they believe are in play here, but that only adds fuel to the fire unnecessarily. We need to wait and see what is really happening here, not let fear of the unknown overtake us." —— AP reporters Mike Catalini in Morrisville, Pennsylvania; and Wayne Parry in Point Pleasant, New Jersey, contributed to this report.
GIS introduces ‘Immigration 360’ to automate passenger processing and data managementA New Year will bring a cold snap across the country with temperatures set to drop as low as -4C, Met Éireann has said. Ahead of the cold snap, the national forecaster has issued a Status Yellow rain warning for Donegal. The warning will be in place from 11am tomorrow until 11am on New Year’s Eve. Possible impacts include the risk of localised flooding, poor visibility and difficult travelling conditions. Met Éireann meteorologist Mark Bowe said New Year’s Eve and New Year’s Day are expected to be “very windy, blustery and wet”. "We're going to have a series of low-pressure centres move over the country on Tuesday and Wednesday," he told the Irish Independent . Those planning to travel to the north for New Year’s Eve can expect strong winds that might lead to some travel disruption on Tuesday, as the UK’s Met Office has issued a yellow wind warning for all six counties – Antrim, Armagh, Down, Fermanagh, Tyrone and Derry. The warning will be in place from 6am until 7pm on New Year’s Eve. Mr Bowe said the cold snap will begin just after New Year’s Day on Wednesday. “Once those lows move away on Wednesday and push further east, in behind them, there's going to be a northerly airflow over the country,” he said. "That's going to persist right throughout the end of the week, so it's going to feel certainly a lot different than it has been as of late. “Our temperatures are going to plummet for the second half of the week. Our overnight lows are going to get well down below freezing for Wednesday, Thursday and Friday nights. “Similarly, our daytime highs during those days will be struggling to reach the low single figures, perhaps staying just around freezing as well, especially on Thursday and Friday. “On Thursday itself, the daytime highs are going to struggle to reach around 2 or 3C, but possibly even staying around freezing in parts of the north. “But the overnight lows are going to get down to maybe -3 and -4C and it'll be rather similar again, pushing into Friday with our daytime highs really struggling – just in those very low single figures. "The overnight lows on a Friday again [will be] well below freezing,” he added. Today will be mostly dry, with a mixture of cloud and sunny spells. However, the north and west of the country might see occasional patches of light rain or drizzle. The highest temperatures will range between 8 and 11C as the day will turn breezy, with strong winds near the western and northwestern coasts. We need your consent to load this Social Media content. We use a number of different Social Media outlets to manage extra content that can set cookies on your device and collect data about your activity. It will remain dry tonight in most areas, with only a few spots of light rain or drizzle. Later at night, the north and west might experience more frequent outbreaks of rain near northern coasts. Temperatures are set to drop to 4 to 9C while it will be the coolest in the south and southeast, with winds remaining strong in the north and west. Tomorrow will be cloudy for most, bringing outbreaks of rain developing through the morning for parts of Ulster and Connacht. Elsewhere might remain mostly dry for the day and enjoy some bright or sunny spells - with just the odd shower possible. Temperatures will range between 9 and 12C, accompanied by strong winds in the north and west. A wet and rather windy Monday night will bring showery outbreaks of rain extending eastwards over the country, with some heavy falls possible. Temperatures will drop to 6 and 9C. Photo: Stock image 7-Day Weather Forecast: 23rd December - 29th December 2024 Meanwhile, New Year's Eve will be rather windy for much of the day. Munster and south Leinster might see widespread rain in the morning, with hazy sunny spells and isolated showers over the northern half of the country. A mixture of clouds and rain will build from the southwest in the afternoon and evening. Temperatures might range between 8 and 12C, with strong winds near western and northwestern coasts - but they will ease in the evening. It will turn wet and windy overnight as rain will continue to extend northeastwards and might turn heavy in places - especially in the north and west. Met Éireann has also warned of spot flooding which might be possible on New Year's Eve night. Temperatures will range between 0 to 5C over the northern half of the country and 5 and 9C further south. The rest of the week will bring much colder weather as overnight temperatures are set to drop below freezing. It will be cold, bright and largely dry with widespread frosts developing during the nights and stubborn to clear some areas during the days. New Year’s Day will be very windy, with widespread heavy rain at first, which will later clear from most areas. However, the showery rain will persist in the north and west. Temperatures will range between 8 and 12C on Wednesday before dropping to -3 to +1C during the cold night, accompanied by widespread frost and ice. Thursday will remain cold, largely dry, and sunny, with a few light showers along the northern coasts while the southern coast might see cloudier conditions. Temperatures will be between 3 and 6C during the day and drop as low as -4 to +1C at night, with widespread frosts expected.
Volkswagen workers plan to launch extended strikes starting Monday, escalating a heated conflict with management over layoffs and what would be the first factory closures on German soil for Europe's largest automaker, according to a union statement on Thursday. The IG Metall union said workers would down tools for four hours at nine different sites in so-called "warning" strikes across the country, twice as long as the first round of industrial action at the start of December. The walkouts are timed to coincide with the next round of talks between Volkswagen and labor representatives over cost-cutting measures that the company says are vital to staying competitive against rising costs and foreign rivals. Volkswagen on Thursday said the management and workers representatives remained in dialogue to collaboratively develop viable, long-term solutions that balance economic stability and secure employment prospects. The crisis at Europe's largest carmaker has hit Germany at a time of economic uncertainty and domestic political upheaval, as well as wider turmoil among the region's automakers. Volkswagen Group CEO Oliver Blume on Wednesday had defended his decisions as necessary in a rapidly changing environment, saying management could not operate "in a fantasy world." "It borders on mockery when Oliver Blume stands in front of the workforce and wishes them a Merry Christmas, while at the same time, the VW board would prefer to put letters of termination under the Christmas tree for the employees," IG Metall negotiator Thorsten Groeger said on Thursday. "We will now step up our efforts on December 9th and thus increase the pressure on the company at the negotiating table," he said in a statement. Europe's car sector is in turmoil, with thousands of jobs on the line at automakers and their suppliers, all suffering from a weakening market on the continent and a slower-than-expected take-up of electric vehicles. On Monday morning, thousands of VW employees are expected to attend a rally in Wolfsburg, where VW is headquartered, shortly before the start of negotiations. Workers could increase pressure if no agreement is struck during next week's negotiations, union officials have signaled, leading to longer and possibly even open-ended strikes.
Agilent Technologies, Inc. ( NYSE:A – Get Free Report ) announced a quarterly dividend on Wednesday, November 20th, Wall Street Journal reports. Stockholders of record on Tuesday, December 31st will be paid a dividend of 0.248 per share by the medical research company on Wednesday, January 22nd. This represents a $0.99 dividend on an annualized basis and a dividend yield of 0.73%. The ex-dividend date is Tuesday, December 31st. This is a boost from Agilent Technologies’s previous quarterly dividend of $0.24. Agilent Technologies has raised its dividend payment by an average of 19.0% annually over the last three years. Agilent Technologies has a payout ratio of 17.8% meaning its dividend is sufficiently covered by earnings. Equities analysts expect Agilent Technologies to earn $6.16 per share next year, which means the company should continue to be able to cover its $0.99 annual dividend with an expected future payout ratio of 16.1%. Agilent Technologies Price Performance A stock opened at $135.54 on Friday. The firm has a 50-day moving average of $135.33 and a 200 day moving average of $136.57. The company has a debt-to-equity ratio of 0.57, a current ratio of 2.09 and a quick ratio of 1.58. The company has a market cap of $38.71 billion, a P/E ratio of 30.67, a PEG ratio of 4.48 and a beta of 1.07. Agilent Technologies has a 1 year low of $124.16 and a 1 year high of $155.35. Analyst Ratings Changes A number of research firms have recently weighed in on A. JPMorgan Chase & Co. reduced their target price on shares of Agilent Technologies from $165.00 to $160.00 and set an “overweight” rating on the stock in a research report on Tuesday, November 26th. Bank of America cut their price objective on shares of Agilent Technologies from $153.00 to $150.00 and set a “neutral” rating on the stock in a report on Friday, December 13th. Evercore ISI lifted their target price on shares of Agilent Technologies from $135.00 to $145.00 and gave the company an “in-line” rating in a report on Tuesday, October 1st. Wells Fargo & Company cut their price target on Agilent Technologies from $157.00 to $155.00 and set an “overweight” rating on the stock in a research note on Monday, December 9th. Finally, Sanford C. Bernstein lowered their price objective on Agilent Technologies from $140.00 to $135.00 and set a “market perform” rating for the company in a research note on Tuesday, November 26th. One research analyst has rated the stock with a sell rating, six have given a hold rating and eight have assigned a buy rating to the company. According to MarketBeat.com, the company currently has an average rating of “Hold” and an average target price of $143.62. View Our Latest Analysis on Agilent Technologies Agilent Technologies Company Profile ( Get Free Report ) Agilent Technologies, Inc provides application focused solutions to the life sciences, diagnostics, and applied chemical markets worldwide. The company operates in three segments: Life Sciences and Applied Markets, Diagnostics and Genomics, and Agilent CrossLab. The Life Sciences and Applied Markets segment offers liquid chromatography systems and components; liquid chromatography mass spectrometry systems; gas chromatography systems and components; gas chromatography mass spectrometry systems; inductively coupled plasma mass spectrometry instruments; atomic absorption instruments; microwave plasma-atomic emission spectrometry instruments; inductively coupled plasma optical emission spectrometry instruments; raman spectroscopy; cell analysis plate based assays; flow cytometer; real-time cell analyzer; cell imaging systems; microplate reader; laboratory software; information management and analytics; laboratory automation and robotic systems; dissolution testing; and vacuum pumps, and measurement technologies. Featured Stories Receive News & Ratings for Agilent Technologies Daily - Enter your email address below to receive a concise daily summary of the latest news and analysts' ratings for Agilent Technologies and related companies with MarketBeat.com's FREE daily email newsletter .INDIANAPOLIS (AP) — There's more than just school pride and bragging rights to all that bellyaching over who might be in and who might be out of college football 's first 12-team playoff. Read this article for free: Already have an account? To continue reading, please subscribe: * INDIANAPOLIS (AP) — There's more than just school pride and bragging rights to all that bellyaching over who might be in and who might be out of college football 's first 12-team playoff. Read unlimited articles for free today: Already have an account? INDIANAPOLIS (AP) — There’s more than just school pride and bragging rights to all that bellyaching over who might be in and who might be out of college football ‘s first 12-team playoff. Try the more than $115 million that will be spread across the conferences at the end of the season, all depending on who gets in and which teams go the farthest. According to the College Football Playoff website, the 12 teams simply making the bracket earn their conferences $4 million each. Another $4 million goes to conferences whose teams get into the quarterfinals. Then, there’s $6 million more for teams that make the semifinals and another $6 million for those who play for the title. Most of this bonanza comes courtesy of ESPN, which is forking over $1.3 billion a year to televise the new postseason. A lot of that money is already earmarked — more goes to the Big Ten and Southeastern Conference than the Big 12 or Atlantic Coast — but a lot is up for grabs in the 11 games that will play out between the opening round on Dec. 20 and the final on Jan. 20. In all, the teams that make the title game will bring $20 million to their conferences, all of which distribute that money, along with billions in TV revenue and other sources, in different ways. In fiscal 2022-23, the Big Ten, for instance, reported revenue of nearly $880 million and distributed about $60.5 million to most of its members. The massive stakes might help explain the unabashed lobbying coming from some corners of the football world, as the tension grows in advance of Sunday’s final rankings, which will set the bracket. Earlier this week, Big 12 commissioner Brett Yormark lit into the selection committee, which doesn’t have a single team higher than 15 in the rankings. That does two things: It positions the Big 12 as a one-bid league, and also threatens to makes its champion — either Arizona State or Iowa State — the fifth-best among conference titlists that get automatic bids. Only the top four of those get byes, which could cost the Big 12 a spot in the quarterfinals — or $4 million. “The committee continues to show time and time again that they are paying attention to logos versus resumes,” Yormark said this week, while slamming the idea of teams with two losses in his conference being ranked worse than teams with three in the SEC. The ACC is also staring at a one-bid season with only No. 8 SMU inside the cut line of this week’s projected bracket. Miami’s loss last week all but bumped the Hurricanes out of the playoffs, a snub that ACC commissioner Jim Phillips said left him “incredibly shocked and disappointed.” “As we look ahead to the final rankings, we hope the committee will reconsider and put a deserving Miami in the field,” Phillips said in a statement. The lobbying and bickering filters down to the campuses that feel the impact. And, of course, to social media. Winnipeg Jets Game Days On Winnipeg Jets game days, hockey writers Mike McIntyre and Ken Wiebe send news, notes and quotes from the morning skate, as well as injury updates and lineup decisions. Arrives a few hours prior to puck drop. One of the most entertaining episodes came earlier this week when athletic directors at Iowa State and SMU went back and forth about whose team was more deserving. There are a few stray millions that the selection committee cannot really influence, including a $3 million payment to conferences that make the playoff. In a reminder that all these kids are going to school, after all, the conferences get $300,000 per football team that meets academic requirements to participate in the postseason. (That’s basically everyone). ___ Get poll alerts and updates on the AP Top 25 throughout the season. Sign up here. AP college football: https://apnews.com/hub/ap-top-25-college-football-poll and https://apnews.com/hub/college-football Advertisement Advertisement
Pride, bragging rights and more than $115M at stake when final college playoff rankings come out
Google’s new AI projects aren’t ready for the masses yet. Good!WASHINGTON (AP) — An imprisoned far-right extremist group leader who was the top target of the federal investigation of the Jan. 6, 2021, riot at the U.S. Capitol balked at answering a prosecutor's questions about the attack when he testified on Thursday at the trial of a police officer accused of leaking him confidential information. A federal judge warned former Proud Boys national chairman Enrique Tarrio that he could face consequences, including an order holding him in contempt of court, if he continued to refuse to answer the prosecutor's questions. Tarrio completed his testimony without incurring any sanctions from the judge. Tarrio, who is serving a 22-year prison sentence for a plot to keep Donald Trump in the White House after the 2020 election, waived his Fifth Amendment right against self-incrimination when he agreed to testify as a defense witness at the bench trial of retired Metropolitan Police Department Lt. Shane Lamond. “What that means is you have to answer all the questions. You don't get to pick and choose,” U.S. District Judge Amy Berman Jackson told Tarrio after he initially refused to answer whether Proud Boys were at the Capitol on Jan. 6. Dozens of Proud Boys, including Tarrio, are among the 1,500 people who have been charged with federal crimes related to the Capitol siege. A jury convicted Tarrio and three lieutenants of seditious conspiracy and other crimes last year after a months-long trial in the same courthouse where Lamond is on trial this week. Tarrio complained that the prosecutor, Rebecca Ross, shouldn't have “free reign” to ask him questions about Jan. 6. Lamond is on trial for charges that he lied about providing Tarrio with confidential information about a police investigation of Proud Boys who burned a Black Lives Matter banner in December 2020. “This case is not a Jan. 6 case,” he told the judge, arguing that he didn't “completely” waive his Fifth Amendment rights. “There is not a half of a Fifth Amendment privilege,” the judge responded. When Tarrio told her, “We'll agree to disagree,” the judge chuckled and replied, “Well, I'll just say, ‘You’re not in charge.'” Tarrio was the first witness to testify for Lamond's defense against charges that he obstructed justice and made false statements about his communications with Tarrio. The judge will decide the case against Lamond after hearing testimony without a jury. On Monday, the judge said Tarrio was waiting for the outcome of last month’s presidential election before deciding whether to testify at Lamond’s trial. President-elect Trump, who repeatedly has vowed to pardon people convicted of Capitol riot charges, suggested he would consider pardoning Tarrio. Tarrio was sentenced to more than five months in jail for burning the banner that was stolen in December 2020 from a historic Black church in downtown Washington, and for bringing two high-capacity firearm magazines into the district. Tarrio was arrested in Washington two days before the Jan. 6 siege. The Miami resident wasn’t at the Capitol when a mob of Trump supporters stormed the building and interrupted the congressional certification of Biden’s 2020 electoral victory. During the trial's opening statements on Monday, a prosecutor said Lamond was a “Proud Boys sympathizer” who warned Tarrio about his impending arrest for the banner’s destruction and later lied to investigators about their communications. Police officers who investigated the banner’s destruction testified that it would have helped them to know that Tarrio had privately confessed to Lamond that he burned the banner. The Proud Boys leader also publicly admitted on social media and on a podcast that he had burned the banner. Tarrio testified on Thursday that he didn’t confess to Lamond or receive any confidential information from him. Tarrio said he came to Washington two days before Jan. 6 because he wanted to be arrested for the banner burning but released in time to attend then-President Trump’s Jan. 6 “Stop the Steal” rally. “I wanted to get this over with,” Tarrio said. He also said he thought that his arrest before the rally would help “put up a circus tent" and generate publicity for his group's message. “I wanted to show what the Department of Justice was, and I was dedicated to that cause with everything in me,” he said. Lamond, who met Tarrio in 2019, had supervised the intelligence branch of the police department’s Homeland Security Bureau. He was responsible for monitoring groups like the Proud Boys when they came to Washington. Lamond’s indictment accuses him of lying to and misleading federal investigators when they questioned him in June 2021 about his contacts with Tarrio. Lamond, of Stafford, Virginia, was arrested in May 2023. He retired from the police department that same month.Sanctuary Advisors LLC Has $267,000 Position in Wyndham Hotels & Resorts, Inc. (NYSE:WH)
Here's How Much $100 Invested In Synopsys 15 Years Ago Would Be Worth TodayIRVING, Texas (AP) — A rape allegation against rapper Jay-Z, whose company Roc Nation has produced some of the NFL's entertainment presentations including the Super Bowl halftime show, won’t impact the league's relationship with the music mogul. “We’re aware of the civil allegations and Jay-Z’s really strong response to that," NFL Commissioner Roger Goodell said Wednesday after the conclusion of the league's winter meetings. "We know the litigation is happening now. From our standpoint, our relationship is not changing with them, including our preparations for the next Super Bowl.” A woman who previously sued Sean “Diddy” Combs, alleging she was raped at an awards show after-party in 2000 when she was 13 years old, amended the lawsuit Sunday to include a new allegation that Jay-Z was also at the party and participated in the sexual assault. Jay-Z, whose real name is Shawn Carter, said the rape allegation made against him is part of an extortion attempt . The 24-time Grammy Award winner called the allegations “idiotic” and “heinous in nature” in a statement released by Roc Nation, one of his companies. The NFL teamed up with Jay-Z’s Roc Nation in 2019 for events and social activism. The league and the entertainment company extended their partnership a few months ago. Kendrick Lamar will perform the Super Bowl halftime show at The Caesars Superdome in New Orleans on Feb. 9. Roc Nation and Emmy-winning producer Jesse Collins will serve as co-executive producers of the halftime show. Beyonce, who is married to Jay-Z, will perform at halftime of the Baltimore Ravens-Houston Texans game on Christmas. “I think they’re getting incredibly comfortable with not just with the Super Bowl but other events they’ve advised us on and helped us with,” Goodell said. “They’ve been a big help in the social justice area to us on many occasions. They’ve been great partners.” AP NFL: https://apnews.com/hub/nflLawmakers edge closer to deal on government fundingTEL AVIV, Israel (AP) — An Israeli hospital says Prime Minister Benjamin Netanyahu has undergone successful prostate surgery. Jerusalem’s Hadassah Medical Center said his prostate was removed late Sunday. Netanyahu was placed under full anesthesia for the procedure. Doctors said he was awake and recovering Sunday night. Netanyahu’s office had said Justice Minister Yariv Levin, a close ally, would serve as acting prime minister during the procedure. Doctors ordered the operation after detecting an infection last week. Netanyahu is expected to remain hospitalized for several days. THIS IS A BREAKING NEWS UPDATE. AP’s earlier story follows below. TEL AVIV, Israel (AP) — Israeli Prime Minister Benjamin Netanyahu is having his prostate removed on Sunday, his office said, a procedure that comes as he manages multiple crises including the war in Gaza and his trial for alleged corruption . Netanyahu, who has had a series of health issues in recent years, has gone to great lengths to bolster a public image of himself as a healthy, energetic leader. During his trial this month, he boasted about working 18-hour days, accompanied by a cigar. But as Israel's longest-serving leader, such a grueling workload over a total of 17 years in power could take a toll on his well-being. Netanyahu, 75, is among older world leaders including U.S. President Joe Biden, 82 , President-elect Donald Trump, 78 , Brazil's President Luiz Inácio Lula da Silva , 79, and Pope Francis , 88, who have come under scrutiny for their age and health issues. Netanyahu's latest condition is common in older men, but the procedure has had some fallout. The judges overseeing his trial accepted a request from his lawyer on Sunday to call off three days of testimony scheduled this week. The lawyer, Amit Hadad, had argued that Netanyahu would be fully sedated for the procedure and hospitalized for “a number of days.” Netanyahu's office said Justice Minister Yariv Levin, a close ally, would serve as acting prime minister during the procedure. With so much at stake, Netanyahu’s health in wartime is a concern for both Israelis and the wider world. A turbulent time in the region As Israel’s leader, Netanyahu is at the center of major global events that are shifting the Middle East . With the dizzying pace of the past 14 months, being incapacitated for even a few hours can be risky. Netanyahu will be in the hospital at a time when international mediators are pushing Israel and Hamas to reach a ceasefire in Gaza and as fighting between Israel and Yemen’s Iran-backed Houthi rebels intensifies . Prostate issues are common and in many cases easily treatable. Still, the procedure puts a dent in Netanyahu’s image of vigor at a time when he would want to project strength more than ever, both to an Israeli audience navigating constant threats as well as to Israel’s enemies looking to expose its weaknesses. Previous health issues, including a heart condition Netanyahu insists he is in excellent health. His office releases footage of him touring war zones in full protective gear flanked by military officers, or meeting with defense officials on windswept hilltops in youthful dark shades and puffer jackets. But that image was shattered last year when Netanyahu’s doctors revealed that he had a heart condition , a problem that he had apparently long known about but concealed from the public. A week after a fainting spell, Netanyahu was fitted with a pacemaker to control his heartbeat. Only then did staff at the Sheba Medical Center reveal that Netanyahu has for years experienced a condition that can cause irregular heartbeats. The revelation came as Netanyahu was dealing with massive anti-government protests. The news about a chronic heart problem stoked further anger and distrust during extreme political polarization in Israel. Last year, Netanyahu was rushed to the hospital for what doctors said likely was dehydration . He stayed overnight, prompting his weekly Cabinet meeting to be delayed. Earlier this year, Netanyahu underwent hernia surgery , during which he was under full anesthesia and unconscious. Levin served as acting prime minister during the operation. Recovery can be quick According to Netanyahu’s office, the Israeli leader was diagnosed with a urinary tract infection on Wednesday stemming from a benign enlargement of his prostate. The infection was treated successfully with antibiotics, but Sunday's procedure will remove his prostate. Complications from prostate enlargement are common in men in their 70s and 80s, Dr. Shay Golan, head of the oncology urology service at Israel’s Rabin Medical Center, told Israeli Army Radio. Golan spoke in general terms and was not involved in Netanyahu’s care or treatment. He said an enlarged prostate can block proper emptying of the bladder, leading to a build-up of urine that can lead to an infection or other complications. After medicinal treatment, doctors can recommend a procedure to remove the prostate to prevent future blockages, Golan said. In Netanyahu’s case, because the prostate is not cancerous, Golan said doctors will likely perform an endoscopic surgery, carried out by inserting small instruments into a body cavity, rather than making surgical cuts in the abdomen to reach the prostate. The procedure lasts about an hour, Golan said, and recovery is quick. He said that aside from catheter use for one to three days after the procedure, patients can return to normal activity without significant limitations.
MGX-001, utilizing a highly specific and efficient MG29-1 nuclease, exhibits no identifiable off-target editing MG29-1 nuclease targeting the albumin safe harbor locus showed no evidence of translocations in primary human hepatocytes Metagenomi Adenine Base Editor (ABE) demonstrates no detectable translocations and no significant genomic base composition differences in primary T-cells EMERYVILLE, Calif., Dec. 11, 2024 (GLOBE NEWSWIRE) -- Metagenomi, Inc. (Nasdaq: MGX), a precision genetic medicines company committed to developing curative therapeutics for patients using its proprietary gene editing toolbox, today presented a talk titled “Specific and efficient genome editing with metagenomics-derived tools for in vivo and ex vivo therapeutic applications” at the Nature Conference: RNA at the Bench and Bedside IV. “We believe the value proposition for single-dose gene editing therapies requires exquisite specificity characterization to ensure safety and efficacy. Today’s presentation highlights the precision of Metagenomi’s next-generation nucleases and ABEs, discovered through the company’s proprietary metagenomics platform and tailored for both in vivo and ex vivo therapeutic applications,” said Alan Brooks, SVP and Head of Preclinical. “MGX-001, Metagenomi’s development candidate for hemophilia A, which utilizes the novel nuclease MG29-1, exhibits no identifiable off-target editing using a series of orthogonal assays employed to evaluate potential off-target sites in the genome. The MG29-1 nuclease targeting the albumin safe harbor locus showed no evidence of translocations in primary human hepatocytes. For Metagenomi’s novel next-generation ABE for ex vivo cell therapy indications via multiplex editing, the data showed no detectable translocations and no significant genomic base composition differences in primary T-cells when compared to unedited cells. These examples demonstrate our strong capabilities in developing highly specific next-generation gene editing tools and support the company’s ability to potentially progress these systems toward the clinic for the benefit of patients.” About Metagenomi Metagenomi is a precision genetic medicines company committed to developing curative therapeutics for patients using its proprietary, comprehensive metagenomics-derived toolbox. Metagenomi is harnessing the power of metagenomics, the study of genetic material recovered from the natural environment, to unlock four billion years of microbial evolution to discover and develop a suite of novel editing tools capable of correcting any type of genetic mutation found anywhere in the genome. Its comprehensive genome editing toolbox includes programmable nucleases, base editors, and RNA and DNA-mediated integration systems (including prime editing systems and clustered regularly interspaced short palindromic repeat associated transposases (CAST)). Metagenomi believes its diverse and modular toolbox positions the company to access the entire genome and select the optimal tool to unlock the full potential of genome editing for patients. For more information, please visit https://metagenomi.co. Cautionary Note Regarding Forward‐Looking Statements This press release contains “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934, each as amended. Such statements, which are often indicated by terms such as “anticipate,” “believe,” “could,” “estimate,” “expect,” “goal,” “intend,” “look forward to,” “may,” “plan,” “potential,” “predict,” “project,” “should,” “will,” “would” and similar expressions, include, but are not limited to, any statements relating to our growth strategy and product development programs, including the timing of and our ability to conduct IND-enabling studies, make regulatory filings such as INDs, statements concerning the potential of therapies and product candidates, and any other statements that are not historical facts. Forward-looking statements are based on management’s current expectations and are subject to risks and uncertainties that could negatively affect our business, operating results, financial condition, and stock value. Factors that could cause actual results to differ materially from those currently anticipated include: risks relating to our growth strategy; our ability to obtain, perform under, and maintain financing and strategic agreements and relationships; risks relating to the results of research and development activities; risks relating to the timing of starting and completing clinical trials; uncertainties relating to preclinical and clinical testing; our dependence on third party suppliers; our ability to attract, integrate and retain key personnel; the early stage of products under development; our need for substantial additional funds; government regulation; patent and intellectual property matters; competition; as well as other risks described in “Risk Factors,” in our most recent Form 10-K and our most recent 10-Qs on file with the Securities and Exchange Commission. We expressly disclaim any obligation or undertaking to release publicly any updates or revisions to any forward-looking statements contained herein to reflect any change in our expectations or any changes in events, conditions or circumstances on which any such statement is based, except as required by law, and we claim the protection of the safe harbor for forward-looking statements contained in the Private Securities Litigation Reform Act of 1995. Contact: Simon Harnest - CIO, SVP Investor Relations IR@metagenomi.co