Breaking News Don't miss out on the headlines from Breaking News. Followed categories will be added to My News. Manchester City's crisis continued with a 2-0 defeat away to Juventus in the Champions League on Wednesday, while Pep Guardiola's old club Barcelona beat Borussia Dortmund to clinch a spot in the knockout stage of Europe's elite club competition. Arsenal, AC Milan, Atletico Madrid, Lille, Feyenoord and Stuttgart were also victorious, but City's latest loss in a miserable run will dominate the headlines. The 2023 European champions succumbed in Turin as Dusan Vlahovic put Juventus ahead early in the second half when goalkeeper Ederson was unable to keep out his header. Ilkay Gundogan was denied an equaliser by a fine Michele Di Gregorio save, before Weston McKennie made it 2-0 with a fine acrobatic finish in the 75th minute. The result leaves Juventus on 11 points with two games left, a tally that is expected to be enough to guarantee them at least a place in the knockout phase play-offs. City, meanwhile, have now won just once in 10 in all competitions, with seven defeats in that time. With just eight points, they currently sit 22nd in the standings, in which the top 24 advance to the knockouts. Their next game will be crucial, as they travel to a Paris Saint-Germain side who sit a point beneath Guardiola's men. "We have to get points, we'll go to Paris to try and do that and the same goes for the final match at home (to Club Brugge)," Guardiola told Amazon Prime in Italy. Barcelona are second in the standings with 15 points, behind only Liverpool, after beating Dortmund 3-2 in a thriller in Germany, with Ferran Torres their hero. Raphinha fired Barca ahead with his 17th goal of the season, early in a remarkable second half. Serhou Guirassy equalised with a penalty on the hour mark, but substitute Torres put Barca back in front on 75 minutes, converting the loose ball after Fermin Lopez's shot was saved. Guirassy scored again for a quick equaliser, only for Torres to strike once more and win the game for Barca with five minutes left. Barcelona's tally leaves them, like Liverpool, ideally placed to finish in the top eight, which means direct progress to the last 16 without having to go through the play-offs. - Saka stars, Arsenal cruise - Arsenal are third in the standings on 13 points after easing to a 3-0 win over Monaco in London. Bukayo Saka scored twice, putting the Gunners ahead in the first half and making it 2-0 on 78 minutes as the hosts pounced on disastrous Monaco defending. Saka then turned provider for the late third, with substitute Kai Havertz credited with the final touch. Mikel Arteta's team are one of six sides on 13 points, with Lille also on that tally after edging Sturm Graz 3-2 in France thanks to a fine late winner from Hakon Haraldsson. Lille were 2-0 up through Osame Sahraoui and Mitchel Bakker, only for goals by Otar Kiteishvili and Mika Biereth to bring the Austrian champions back level. However, Icelandic midfielder Haraldsson secured Lille's fourth win of the campaign. Atletico eased to a 3-1 victory over Slovan Bratislava, with Antoine Griezmann scoring twice after Julian Alvarez had opened the scoring with an excellent strike. David Strelec pulled one back for the Slovaks, who are one of three teams already eliminated having lost six games out of six. The others are RB Leipzig and Young Boys. - Milan grab late winner - Milan defeated Red Star Belgrade 2-1 at San Siro with Tammy Abraham grabbing the winner three minutes from time. Rafael Leao had put Milan ahead only for Nemanja Radonjic to equalise for the Serbian side, who have lost five of their six games and are surely heading out. Benfica edged closer to a play-off spot with a 0-0 draw at home to Bologna of Italy, who have scored just one goal in six games and will go no further. Feyenoord stayed on course to go through after beating Sparta Prague 4-2 in Rotterdam, with Gernot Trauner, Igor Paixao, Anis Hadj Moussa and Santiago Gimenez netting their goals. Stuttgart kept alive their hopes of progress by coming from behind to beat Young Boys 5-1. Lukasz Lakomy put Young Boys ahead but Angelo Stiller levelled before Enzo Millot, Chris Fuehrich, Josha Vagnoman and Yannik Keitel all scored in the second half. The next round of Champions League games is scheduled for January 21 and 22, with the league phase concluding the following week. as/jc Originally published as Juve deepen Man City crisis, Barcelona into Champions League knockouts More related stories Sport ‘Privilege’: Sonny Bill’s shock career move A global sports star known for his deep faith and “passion for social equity” has made a surprising career change. Read more Breaking News ‘If I refuse?’: Violent man’s wild question A violent offender is back in the community, but a wild exchange with a Supreme Court justice suggests he might struggle to fit in. Read more
Supreme Facility Management Limited, a leader in Integrated Facilities Management, is poised to launch its Initial Public Offering (IPO) on December 11, 2024, aiming to raise up to Rs 50 Crore. The shares, ranging from Rs 72 to Rs 76, will debut on the National Stock Exchange's Emerge platform. The IPO issue comprises 65,79,200 equity shares pegged at a face value of Rs 10 each. Target allocations include up to 6,25,600 shares for Qualified Institutional Buyers, not less than 28,11,200 shares for Non-Institutional Investors, and not less than 28,12,800 shares for Retail Investors, alongside 3,29,600 shares reserved for market makers. Proceeds are intended to fortify working capital and fuel strategic acquisitions, thus reinforcing Supreme's market presence. The IPO, managed by Khandwala Securities Limited and KFin Technologies Limited as registrar, closes on December 13, 2024. Industry experts affirm the initiative as timely, given the sector's robust growth trajectory. (With inputs from agencies.)Ball Corp. stock rises Wednesday, still underperforms marketTrump names Andrew Ferguson as head of Federal Trade Commission to replace Lina Khan
NoneFerguson is already one of the FTC’s five commissioners, which is currently made up of three Democrats and two Republicans.
Cowboys star G Zack Martin doubtful to play vs. CommandersDonald Trump is returning to the world stage. So is his trolling
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Colgate-Palmolive Co. stock underperforms Thursday when compared to competitors despite daily gainsAs part of a national “moonshot” to cure blindness, researchers at the CU Anschutz Medical Campus will receive as much as $46 million in federal funding over the next five years to pursue a first-of-its-kind full eye transplantation. “This is no easy undertaking, but I believe we can achieve this together,” said Dr. Kia Washington, the lead researcher for the University of Colorado-led team, during a press conference Monday. “And in fact I’ve never been more hopeful that a cure for blindness is within reach.” The CU team was one of four in the United States that received funding awards from the federal Advanced Research Projects Agency for Health , or ARPA-H. The CU-based group will focus on achieving the first-ever vision-restoring eye transplant by using “novel stem cell and bioelectronic technologies,” according to a news release announcing the funding. The work will be interdisciplinary, Washington and others said, and will link together researchers at institutions across the country. The four teams that received the funding will work alongside each other on distinct approaches, though officials said the teams would likely collaborate and eventually may merge depending on which research avenues show the most promise toward achieving the ultimate goal of transplanting an eye and curing blindness. Dr. Calvin Roberts, who will oversee the broader project for ARPA-H, said the agency wanted to take multiple “shots on goal” to ensure progress. “In the broader picture, achieving this would be probably the most monumental task in medicine within the last several decades,” said Dr. Daniel Pelaez of the University of Miami’s Bascom Palmer Eye Institute, which also received ARPA-H funding. Pelaez is the lead investigator for that team, which has pursued new procedures to successfully remove and preserve eyes from donors, amid other research. He told The Denver Post that only four organ systems have not been successfully transplanted: the inner ear, the brain, the spinal cord and the eye. All four are part of the central nervous system, which does not repair itself when damaged. If researchers can successfully transplant the human eye and restore vision to the patient, it might help unlock deeper discoveries about repairing damage to the brain and spine, Pelaez said, as well as addressing hearing loss. To succeed, researchers must successfully remove and preserve eyes from donors and then successfully connect and repair the optical nerve, which takes information from the eye and tells the brain what the eye sees. A team at New York University performed a full eye transplant on a human patient in November 2023, though the procedure — while a “remarkable achievement,” Pelaez said — did not restore the patient’s vision. It was also part of a partial face transplant; other approaches pursued via the ARPA-H funding will involve eye-specific transplants. Washington, the lead CU researcher, said she and her colleagues have already completed the eye transplant procedure — albeit without vision restoration — in rats. The CU team will next work on large animals to advance “optic nerve regenerative strategies,” the school said, as well as to study immunosuppression, which is critical to ensuring that patients’ immune systems don’t reject a donated organ. The goal is to eventually advance to human trials. Pelaez and his colleagues have completed their eye-removal procedure in cadavers, he said, and they’ve also studied regeneration in several animals that are capable of regenerating parts of their eyes, like salamanders or zebra fish. His team’s funding will focus in part on a life-support machine for the eye to keep it healthy and viable during the removal process. InGel Therapeutics, a Massachusetts-based Harvard spinoff and the lead of a third team, will pursue research on 3-D printed technology and “micro-tunneled scaffolds” that carry certain types of stem cells as part of a focus on optical nerve regeneration and repair, ARPA-H said. ARPH-A, created two years ago, will oversee the teams’ work. Researchers at 52 institutions nationwide will also contribute to the teams. The CU-led group will include researchers from the University of Southern California, the University of Wisconsin, Indiana University and Johns Hopkins University, as well as from the National Eye Institute . The teams will simultaneously compete and collaborate: Pelaez said his team has communicated with researchers at CU and at Stanford, another award recipient, about their eye-removal research. Related Articles The total funding available for the teams is $125 million, ARPA-H officials said Monday, and it will be distributed in phases, in part dependent on teams’ success. U.S. Rep. Diana DeGette, a Democrat who represents Denver in Congress, acknowledged the recent election results at the press conference Monday and pledged to continue fighting to preserve ARPA-H’s funding under President-elect Donald Trump’s administration. The effort to cure blindness, Washington joked, was “biblical” in its enormity — a reference to the Bible story in which Jesus cures a blind man. She and others also likened it to a moonshot, meaning the effort to successfully put Neil Armstrong and Buzz Aldrin on the moon nearly 50 years ago. If curing blindness is similar to landing on the moon, then the space shuttle has already left the launchpad, Washington said. “We have launched,” she said, “and we are on our trajectory.”
Republican senator prepares ‘DOGE Act’ targeting agencies
United Nations climate talks in Azerbaijan have threatened to collapse after negotiating groups representing island states and some of the least-developed countries walked out of a key meeting. Login or signup to continue reading A number of representatives left the large main hall, with one representative shouting loudly when asked about the status of a deal: "Rejected!" "We are here to negotiate but we have left the room because at the moment we don't have the feeling that we are being heard," Colombia's Environment Minister Susana Muhamad told reporters. European delegation sources at COP29 said they assumed that the negotiations, which had been due to end on Friday before being extended, would continue. Various draft texts are circulating among negotiators in Baku. The European Union, United States and other wealthy countries at the summit agreed to raise their offer of climate funding to $US300 billion ($A462 billion) per year by 2035 to help developing countries grapple with climate change, sources told Reuters on Saturday, after a previous proposal was dismissed as insultingly low. The summit had been due to finish on Friday but ran into overtime as negotiators from nearly 200 countries - who must adopt the deal by consensus - tried to reach agreement on a climate funding plan for the next decade. A $US250 billion proposal for a deal, drafted by Azerbaijan's COP29 presidency on Friday, was deemed woefully insufficient by developing countries. Several groups of countries are demanding more ambitious commitments by industrialised countries to aid funding for action on climate change and adaptation in the coming years. But a rough draft of a new proposal to curb and adapt to climate change on Saturday was getting soundly rejected, especially by African countries and small island states, according to messages relayed from inside. The "current deal is unacceptable for us. We need to speak to other developing countries and decide what to do," Evans Njewa, the chair of the Least Developed Countries group, said. With tensions high, climate activists heckled US climate envoy John Podesta as he left the meeting room. They accused the US of not paying its fair share and having "a legacy of burning up the planet". The last official draft on Friday pledged $US250 billion annually by 2035, more than double the previous goal of $US100 billion set 15 years ago but far short of the annual $US1 trillion-plus that experts say is needed. Developing countries accused the rich of trying to get their way - and a small financial aid package - via a war of attrition. And small island countries, particularly vulnerable to climate change's effects, accused the host country presidency of ignoring them for the entire two weeks. After bidding one of his suitcase-lugging delegation colleagues goodbye and watching the contingent of about 20 enter the meeting room for the EU, Panama chief negotiator Juan Carlos Monterrey Gomez had enough. "Every minute that passes we are going to just keep getting weaker and weaker and weaker. They don't have that issue. They have massive delegations," Gomez said. "This is what they always do. They break us at the last minute. You know, they push it and push it and push it until our negotiators leave. Until we're tired, until we're delusional from not eating, from not sleeping." With developing countries' ministers and delegation chiefs having to catch flights home, desperation sets in, Power Shift Africa's Mohamed Adow said. 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