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2025-01-10
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2 handed seat (BPT) - This article was sponsored and developed by Neurocrine Biosciences, Inc. Cerebral palsy (CP) is a neurodevelopmental disorder affecting movement and posture that begins in early childhood development. It is the most common cause of motor disability in children, affecting about one in 345 children in the United States. 1-2 It may happen as a result of lack of oxygen during or around birth, stroke, infection, a problem with metabolism or other problems that cause injury or affect the development of parts of the brain involved in movement control in the first few years of life. 3 CP is a permanent condition, affecting a person for their entire life. People living with CP typically have motor problems, which may include spasticity (abnormal muscle tightness), dyskinesia (uncontrolled movements) or ataxia (poor muscle control), and many people have a mix of these motor disorders. 4 Dyskinesia due to CP (DCP) is one of the most disabling forms of CP and impacts approximately 10% to 20% of people living with CP. 5-6 According to the Cerebral Palsy Foundation (CPF), the combination of irregular and unpredictable movements (chorea) and twisting and repeating movements (dystonia) often disrupt activities and cause significant functional impairment, including the ability to maintain balance, walk or fine motor control. 7 Heather Riordan, M.D., Neurologist and Movement Disorders Specialist, Director of the Phelps Center for Cerebral Palsy at the Kennedy Krieger Institute, discusses the symptoms of chorea and impact on patients in a video shared on the CPF website here . About 30% of people with DCP are affected mostly by these involuntary and irregular movements (chorea), while dystonia is the predominant motor finding in the remaining 70%. 8 However, it is common for both chorea and dystonia movements to be present together. 6 For people living with DCP, these movements can occur in any region of the body, including the arms and legs, torso and face and may vary in severity. They are often triggered or made worse by stimulation or stress. Because dyskinesia can occur at rest and/or when actively using the body, the problems with movement are very burdensome in day-to-day living, with discomfort and pain affecting the quality of life for people and their caregivers. 9 Jen Lyman, mom to a son with DCP, highlights how dyskinesia makes communicating more difficult. "The most difficult thing about dyskinesia is watching my son struggle to do things that he wants to do, but the extra movements get in the way...special things, such as using a touch screen to video chat with his grandmother, are nearly impossible despite his best efforts to use his hands and fingers. Something so simple, yet so special for him should be effortless." DCP has a wide-ranging impact on the individual, including lifelong challenges with movement, a higher risk of other medical issues, a higher rate of mental health challenges and difficulties with communication. 10-12 "Those of us who have the privilege to serve patients with dyskinetic, hyperkinetic or mixed cerebral palsy see the functional impact of this very challenging type of tone every day," said Susan Biffl, M.D., Rehabilitation Medicine Specialist at Rady Children's Hospital-San Diego and Assistant Professor at UC San Diego School of Medicine. "Patients face challenges with self-care, independence, mobility, communication, fine motor skills that affect occupational and recreational activities, swallowing, social interactions and even sleep. As this tone is variable, it is much more challenging to treat than more consistent tone issues, such as spasticity." Treatment Options There are currently no Food and Drug Administration-approved treatments for DCP. Dystonia and chorea are often managed separately as they respond differently to various treatments, which can make treatment challenging. 3 Most drugs being investigated for DCP have focused on dystonia, and more research is needed to determine potential treatments for chorea. New treatment options are needed to help manage these movement disorders and improve daily function and quality of life for those affected. "After 20 years of caring for individuals with cerebral palsy, I continue to find those with dyskinetic cerebral palsy among the most challenging to treat, largely due to the limited effectiveness of available pharmacologic options," said Joyce Oleszek, M.D., Professor, Department of Physical Medicine and Rehabilitation, University of Colorado School of Medicine. "There is an urgent need for more robust evidence to support pharmacologic treatments for this condition, given its profound impact on function, comfort and quality of life." Ongoing Research Clinical studies are important in the development of treatment options, allowing researchers to evaluate the safety and effectiveness of new medicines. The data from clinical studies are used to determine if an investigational treatment can be approved for use to treat certain disorders. There are ongoing clinical studies evaluating potential treatments for DCP, including one for chorea. Neurocrine Biosciences is conducting the KINECT ® -DCP clinical study, a Phase 3, randomized, double-blind placebo-controlled study investigating the study drug, valbenazine, for the treatment of DCP. The clinical study is currently enrolling children, adolescents and adults six to 70 years of age who have been diagnosed with DCP. "The Cerebral Palsy Foundation is excited to partner with Neurocrine Biosciences on this study," said Rachel Byrne, Executive Director of the Cerebral Palsy Foundation. "We are proud to support strong research that can potentially bring meaningful change to the lives of those living with cerebral palsy." If you or someone you know may be eligible for this research study, please visit the study website for additional information here: FindADCPStudy.com . REFERENCES © 2024 Neurocrine Biosciences, Inc. All Rights Reserved. CAP-NBI-US-0115 12/2024 NBI-98854-DCP3018_11DecMatRelease_v1.0_25November2024

Mercedes Chronos is a bold glimpse of what future generations could be drivingI'll cut to the chase here: I've had enough with the discourse trying to taint the leadership and level of commitment from Dallas Cowboys superstar defensive end Micah Parsons. For a variety of reasons ranging from the fact that he hosts a weekly podcast to his absence from voluntary OTAs this year, Parsons' leadership has been question by fans and media alike. Earlier in the year, 105.3 The Fan even suggested "if Micah Parsons was out of there, there'd be a decent amount of people inside the Ford Center at the Star in Frisco smiling or breathing a sigh of relief." On Monday's gut-wrenching loss to the Cincinnati Bengals, Parsons showed the NFL world why none of it makes sense. Following the blocked-and-muffed punt that cost the Cowboys the game , Parsons was completely beside himself on the sidelines and he even walked off the field before the clock hit zero. As I watched, I couldn't help thinking: "This dude actually believed. Micah genuinely thought the Cowboys could make a run for the playoffs. Even with no Dak Prescott and a long list of injuries, this guy that clearly cares enough about the end result of tonight's game actually thought they'd win and stay alive in the 2024 NFL season." For a good while, Parsons told the media he did all that. That he believed. At the time, it was easy to shrug it off as just a player saying the words he's supposed to when there are cameras and microphones on him. But watching him on Monday, it became crystal clear it was all authentic. When arguably the best player on the roster has that mindset, what's there not to like? Coupled with a double-digit pressure outing, I'm not sure why fans even think Parsons doesn't have the right attitude as a leader of the Cowboys. "I'm hurt," Parsons told reporters postgame between long pauses. "Mhm... Man, I... I wouldn't wish this on anybody... Man, you can't put that into words, to be honest." On Tuesday in his podcast, Parsons opened up about his emotional outburst at the end of the game. "I don't think there's anyone in the world, except for the top three players of all time, like (Michael Jordan, maybe Kobe Bryant), I think I'm in that category of competitiveness," Parsons said. "I don't think there's anyone more competitive than me. And it's heartbreaking for me because I promised you, Cowboys Nation that we'd make a run." Micah Parsons explains his postgame emotions after loss vs. Bengals: 'Damned if I do, damned if I don't... If I went over there and was all laughing with the competition after we lost like that, a lot of people would be mad.' (via The Edge with Micah Parsons) pic.twitter.com/6E3Fa0Tvmy There's no denying Parsons enjoys the spotlight. He enjoys talking and won't shy away from being himself in front of the media even if it means dropping a controversial comment every now and then. But to question this guy's leadership and his desire to win when it's exactly that the Cowboys, and any NFL team for that matter, need is just wild. If Parsons' raw reaction on Monday didn't prove it to fans, I don't know what will. But it's time to drop the bias against the Cowboys' superstar because it likely stems from the fact that he has a podcast. And that's just silly. Ask Travis and Jason Kelce, who both reached the Super Bowl as high-performers while hosting one of the most famous podcasts in the world. This article first appeared on A to Z Sports and was syndicated with permission.

Kendrick Lamar — rap’s undoubted MVP of 2024 — surprised fans on Friday (Nov. 22) with the release of his GNX album. The project seemingly dropped out of the sky without warning around 12 p.m. ET. Filled with 12 tracks, GNX boasts a pair of assists from former TDE running mate SZA , Sam Dew as well as emerging artists such as Deyra Barrera, Ink, Dody 6, AzChike and more. Kendrick was rumored to be cooking up an album in the wake of battling Drake , and the Compton native came through. GNX follows Lamar’s Mr. Morale & the Big Steppers in 2022, which topped the Billboard 200 with 295,000 total units earned in the first week. Sounwave notches co-production credits across the project while Jack Antonoff and Kamasi Washington also make appearances. Lamar dropped off a teaser before the album hit streaming services with the clip featuring what appears to be a 1987 Buick Grand National Regal GNX, which inspired the album title. With the Super Bowl on the horizon, K. Dot will have new music with him when he heads to New Orleans to take the Super Bowl LIX Halftime Show stage in February. Even prior to the album’s arrival, Lamar notched seven Grammy Award nominations earlier this month — five of which came tied to his “Not Like Us” Drake diss. Check out the album and all of the 12 tracks ranked from worst to best below. Kenny weaves through the distorted bounce with a hazy flow with some help from Ink, Siete and Roddy Ricch. The West Coast tribute fails to break through like some of the other stronger tracks on the LP so it’s forced to blend in with the background. “Peekaboo” is a perfect descriptor aligning Lamar’s career. He only comes out of hiding on his own terms to shake up the game and then can go back into hibernation for months without anyone hearing a word, a social media post, a TMZ paparazzi photo or anything from him. As Charlamagne Tha God described him, K. Dot really is rap’s boogeyman or the rap version of WWE legend Undertaker. Was that Kendrick mimicking NBA star Kawhi Leonard’s viral “hey, hey, hey” clip? This guy can work just about anything into the flow of a song. Only Kendrick can turn irrelevant sayings like “Hey now, say now” into a menacing chorus. “The Black know I just strangled me a GOAT,” he raps in a possible jab at Drake following their battle. The pulsating reverb transitions to traditional Cali bounce and Kendrick opens the floor for an assist from emerging L.A. rapper Dody 6. In the midst of the Kendrick-Drake feud, a repeated take in an attempt to ding Lamar was that he rarely uplifted younger artists coming up from Los Angeles. It feels like he intentionally made that part of his story with GNX . Especially with the title track, he shouts about putting the “West Coast back in front of s–t.” Then he takes a back seat as if he’s iconic UCLA head coach John Wooden and allows Young Threat, Peysoh and Hitta J3 to run the three-man weave. “Gloria” serves as Kendrick’s version of Common’s memorable “I Used to Love H.E.R.” In what starts out as a love song, Lamar vulnerably opens up about the complications and toxicities of his relationship with what appears to be his fiancee Whitney. While she had other suitors on their journey, he also had commitment issues. However, the final line reveals K. Dot was talking about his love for his pen with references to writer’s block placating his enduring journey to the top of the food chain in this rap game. A second hat tip to Nas as Kendrick seemingly interpolates the Queensbridge icon’s 2002 “One Mic.” Lamar draws up a scenario of being at heaven’s gates seeking eternal life. He builds out a case about how his life’s practices have prepared him for this moment while powering through trials and tribulations. “I did it with integrity and n—-s still try to hate on me/ Just wait and see, more blood will be spillin, it’s just paint to me,” Kenny promises. A haunting intro sprinkled in with some Latin flavor courtesy of Deyra Berrara. Kendrick balances an ego boost coming off his dominant Drake victory and spewing his version of a State of the Union. All while riding in his GNX bumping Anita Baker. Dot grapples with his Lil Wayne fandom while taking what he hoped was his spot at the Super Bowl LIX Halftime Show in Weezy’s hometown. He was baffled by the backlash and shouted out Nas for showing him love. There aren’t many direct references to his Drake feud, but Lamar lets his disappointment in Snoop be known after the Doggfather reposted Drizzy’s AI-assisted “Taylore Made Freestyle.” “I prayed it was the edibles/ I couldn’t believe it, it was only right for me to let it go,” he raps. An all-star lineup of Jack Antonoff, Sounwave, Cardo and Kamasi Washington are among the cast lending their talents to the luscious production of “Luther” — which builds around a sample of Luther Vandross and Cheryl Lynn’s “If This World Were Mind.” SZA joins the party for her and Kendrick’s fifth collaboration and their chemistry hasn’t taken a step back as they mix vocals with ease for a smooth blend of rapping and singing. K. Dot takes away the world’s darkness and reimagines a society without pain and suffering. Drake attempted to mock Kendrick’s “The Heart” series with his own installment in the decorated series that originated in 2010, but as Lamar made a habit of in their feud, Dot flipped the script to up the score with the real sixth addition on “Heart Pt. 6.” Sounwave and Jack Antonoff lay out an ethereal soundscape built around a soothing Neptune-produced SWV sample for Kendrick to reminisce on his humble beginnings surrounded by his TDE family members like Jay Rock and Ab-Soul. Lamar briefly allows his ego to creep in: “Time flies, I’m carryin’ debates of a top five,” he raps. But also takes accountability for his Black Hippy supergroup falling flat. “I jog my memory, knowin’ Black Hippy didn’t work ’cause of me/ Creatively, I moved on with new concepts in reach,” he candidly admits. It’s another worthy chapter in the books. Sampling Debbie Deb’s “When I Hear Music” banger makes this some of the most fun production across the entire project. Initially teased as a snippet tentatively titled “Broccoli” over the summer, fans were happy to hear the full track live up to the hype. “Squabble Up” gets the shoulders bobbing as Kendrick basks in his status as his most brash self. “Tell me why the fuck you n—s rap if it’s fictional/ Tell me why the fuck you n—s fed if you criminal,” he fires at the opposition. Kendrick yelling “MUSTARD” has to be the next little Kendrick-ism to go viral on social media. The meme possibilities are endless and the “Not Like Us” producer has to at least sample that in the future, right? The beat makes a stark transition from G-Funk to triumphant horns as Lamar lets society know how disgusted he is with where things are at. As we’ve seen on plenty of other tracks, Kenny has no issue letting his hate for certain pockets of culture fly. Songmaking at its finest. Kendrick’s versatility along with his vivid storytelling ability allow him to shine brightest on “Reincarnated,” which samples 2Pac’s “Made N—-z.” Lamar pays homage to the West Coast deity while mirroring an aggressive flow from Pac. He cinematically connects to the spirits of a 1940s guitarist (possibly John Lee Hooker or Jackie Wilson) and a ’60s singer on the Chitlin Circuit (Tammi Terrell or Dinah Washington) who struggled with substance abuse using 8-balls of cocaine as medicine. Dot then turns the camera lens on himself for the final poignant verse as he battles his demons while looking to rewrite the devil’s story. OH MY GOD KENDRICK LAMAR SAMPLED THIS FOR REINCARNATED pic.twitter.com/bqjQaBJGh0

AP Sports SummaryBrief at 6:10 p.m. EST

Global stock markets mostly retreated Tuesday as traders eyed looming US inflation data and a key European interest rate call amid global political upheaval. After winning numerous records in the weeks since the November 5 US presidential election, US stocks fell for the second straight day as analysts pointed to profit-taking. But Alphabet jumped more than five percent after Google showed off a new quantum computing chip that it described as a significant breakthrough in the field, arguing it could lead to advances in drug discovery, fusion energy and other areas. The Paris stock market retreated as French party leaders gathered at President Emmanuel Macron's Elysee Palace office to chart a route towards a new government. The euro also fell ahead of the European Central Bank's monetary policy meeting on Thursday. The ECB is expected to lower interest rates by 25 basis points amid weak eurozone growth. Independent analyst Andreas Lipkow said traders were taking a cautious approach ahead of the ECB meeting. The main US indexes struggled as traders eyed US consumer price inflation (CPI) data due Wednesday, which could play a role in whether the US Federal Reserve decides to cut interest rates next week. On Wall Street, "tomorrow's CPI report is in full focus with a looming rate-decision from the Fed coming," analyst Bret Kenwell of trading platform eToro said in a note. Following recent spending and jobs data "traders have felt even more emboldened to bet on a December rate cut, while the Fed has done little... to quiet that expectation," he added. Earlier, stock markets weighed "concerns that China's economic stimulus measures might not have a long-lasting effect", noted Dan Coatsworth, investment analyst at AJ Bell. The growth plan comes as Beijing contemplates Donald Trump's second term in the White House. The US president-elect has indicated he will reignite his hardball trade policies, fueling fears of another standoff between the economic superpowers. The Shanghai stock market ended higher but Hong Kong fell. Seoul's Kospi index rallied more than two percent after tumbling since President Yoon Suk Yeol declared short-lived martial law on December 3. On the corporate front, shares in Stellantis rose around one percent on the Paris stock exchange after the car giant and Chinese manufacturer CATL announced plans for a $4.3-billion factory making electric-vehicle batteries in Spain. Walgreens Boots Alliance soared 17.7 percent following reports that it could be acquired by private equity firm Sycamore Partners. Boeing jumped 4.5 percent as it announced it was resuming production at two Seattle-area plants that had been shuttered for nearly three months due to a labor strike. New York - Dow: DOWN 0.4 percent at 44,247.83 (close) New York - S&P 500: DOWN 0.3 percent at 6,034.91 (close) New York - Nasdaq Composite: DOWN 0.3 percent at 19,687.24 (close) Paris - CAC 40: DOWN 1.1 percent at 7,394.78 (close) Frankfurt - DAX: DOWN 0.1 percent at 20,329.16 (close) London - FTSE 100: DOWN 0.9 percent at 8,280.36 (close) Hong Kong - Hang Seng Index: DOWN 0.5 percent at 20,311.28 (close) Shanghai - Composite: UP 0.6 percent at 3,422.66 (close) Tokyo - Nikkei 225: UP 0.5 percent at 39,367.58 (close) Seoul - Kospi: UP 2.4 percent at 2,417.84 (close) Euro/dollar: DOWN at $1.0529 from $1.0554 on Monday Pound/dollar: UP at $1.2773 from $1.2757 Dollar/yen: UP at 151.92 yen from 151.21 yen Euro/pound: DOWN at 82.42 from 82.73 pence West Texas Intermediate: UP 0.1 percent at $68.59 per barrel Brent North Sea Crude: UP 0.1 percent at $72.19 per barrel burs-jmb/nroNone

Aston Villa boss Unai Emery has set his sights on automatic qualification to the last 16 of the Champions League after a 3-2 win at RB Leipzig. Ross Barkley’s 85th-minute goal gave them victory in Germany after goals from John McGinn and Jhon Duran early in each half were cancelled out by Lois Openda and Christoph Baumgartner. That sent them up to third in the new league phase of the competition ahead of Wednesday’s games and with matches against Monaco and Celtic to come, Villa have an excellent chance of finishing in the top eight. Job done... in the end 😅 — Aston Villa (@AVFCOfficial) That would mean they would avoid a play-off round to make it through to the last 16 and Emery says that is the target. “Today was key. Juventus at home, we were thinking more to win but in the end we accepted the draw because it was important for a point to be more or less in the top 24,” he told Amazon Prime. “Today was a match we were thinking at the beginning was key to be a contender to be in the top eight with the last two matches to be played. “It is going to be difficult and we have to get some more points but we now have the possibility to achieve this option. “We are going to enjoy and try to get top eight but we have to be happy because we are in the top 24 and maybe even the top 16. “We weren’t contenders in the beginning to get there but now we have to accept it.” Leipzig, who are flying high near the top of the Bundesliga, are out after losing all six matches. They did pose a threat to Villa, who inflicted some of their own problems on themselves, notably a rare gaffe from goalkeeper Emiliano Martinez for Openda’s equaliser. But Emery was happy with his side’s performance. “I try to enjoy and always we want to improve and sometimes it is hard but today the team were performing well, playing seriously and I was enjoying it,” he added. “We tried to overcome the mistakes we made and we did. More or less we were playing consistently. One mistake and they score but then we played very well. “Champions League is very difficult and we have to expect that every team playing at home are feeling strong. We played with consistency and domination.”

Wall Street got back to climbing on Wednesday after the appeared to clear the way for more help for the economy from the Federal Reserve. Wednesday's report said US consumers paid prices in November that were 2.7% higher than a year earlier. That's a slight acceleration from October's inflation rate of 2.6%, but it was exactly what economists were expecting. On Wall Street, Stitch Fix jumped 44.4% after the company that sends clothes to your door reported a smaller loss for the latest quarter than analysts expected. It also gave financial forecasts for the current quarter that were better than expected, including for revenue. Albertsons fell 1.5% after , saying it didn't do enough for their proposed $24.6 billion merger agreement to win regulatory clearance. Albertsons said it's seeking billions of dollars in damages from Kroger, whose stock rose 1%. Mondelez, the company behind Oreo and other food brands, climbed 2.2% after announcing a plan to send cash to shareholders by buying back up to $9 billion of its own stock, the reports. On the losing end of Wall Street, Macy's fell 1% after cutting some of its financial forecasts for the full year of 2024, including for how much profit it expects to make off each $1 of revenue. Dave & Buster's Entertainment sank 20.1% after reporting a worse loss for the latest quarter than expected. It also said CEO Chris Morris has resigned, and the board has been working with an executive-search firm for the last few months to find its next permanent leader.

Dyskinetic Cerebral Palsy: A Closer Look at Symptoms, Diagnosis and Clinical Research Underway

Invest UP seeks ties with academia

NoneMohamed Salah extended Liverpool’s perfect Champions League record as they won 1-0 at Girona to claim a sixth victory out of six. Salah nervelessly converted a 63rd-minute penalty, his 16th goal of the season, after French referee Benoit Bastien had been advised to take another look at Donny van de Beek’s clumsy challenge on Luis Diaz. In the process, he became just the 11th man to score 50 goals in the competition – Real Madrid’s Kylian Mbappe later also joined that exclusive club – on a night when victory at the Estadi Montilivi meant the six-time European champions will enter 2025 sitting proudly at the top of the table. ⭐️ A FIVE STAR PERFORMANCE ⭐️ | — FC Bayern (@FCBayernEN) France international Michael Olise produced a moment of magic to set the seal on Bayern Munich’s demolition of Shakhtar Donetsk and ease them towards the knockout stage. Olise’s brilliant stoppage-time run and finish capped a 5-1 victory for the Germans, in which he had early scored from the penalty spot, in Gelsenkirchen. Kevin’s fifth-minute strike had given the home side the perfect start, but Konrad Laimer levelled before Thomas Muller’s 55th goal in the competition sent the visitors in ahead at the break and set the stage for Olise’s double either side of Jamal Musiala’s strike. Jude Bellingham breathed life back into Real Madrid’s campaign as they held off Atalanta to earn a 3-2 victory in Bergamo. 🫲 🫱 — Real Madrid C.F. 🇬🇧🇺🇸 (@realmadriden) After Charles De Ketelaere had cancelled out Mbappe’s opener from the penalty spot, second-half goals from Vinicius Junior and Bellingham in quick succession put the visitors in charge, although Ademola Lookman’s 65th-minute strike meant the contest was alive until the final whistle. Ross Barkley took Aston Villa a step closer to automatic qualification with a late winner against RB Leipzig in Germany. Villa had led twice through John McGinn and Jhon Duran, but equalisers from Lois Openda and Christoph Baumgartner kept Leipzig in it until substitute Barkley struck five minutes from time to snatch a 3-2 victory. Goals from Goncalo Ramos, Nuno Mendes and substitute Desire Doue – his first in the competition – handed French champions Paris St Germain a much-needed three points after a comfortable 3-0 win at RB Salzburg. He's making a list and checking it twiceB04 won and Nordi scored – nice! 🎅 — Bayer 04 Leverkusen (@bayer04_en) Nordi Mukiele left it late to end Inter Milan’s unbeaten Champions League record as Bayer Leverkusen claimed a dramatic 1-0 victory at the BayArena. Mukiele struck in the 90th minute to inflict a first defeat across six games in this season’s competition on the Serie A champions – it was also the first goal they have conceded. Casper Nielsen came off the bench to fire Club Brugge to a 2-1 home victory over Sporting Lisbon after Eduardo Quaresma’s own goal had handed them a way back into the game following Geny Catamo’s early opener. Julien Le Cardinal’s first-half strike was enough to handed Brest a 1-0 victory over Eredivisie leaders PSV Eindhoven, while Kasper Schmeichel’s save from Marko Pjaca’s close-range 80th-minute header ensured Celtic returned from Dinamo Zagreb with a 0-0 draw.

WASHINGTON (AP) — President Joe Biden faces a stark choice as he contemplates broad preemptive pardons to protect aides and allies from potential retribution by Donald Trump: Does he hew to the institutional norms he’s spent decades defending or flex the powers of the presidency in untested ways. The deliberations so far are largely at the level of White House lawyers. But Biden himself has discussed the topic with senior aides, according to two people familiar with the matter who spoke on condition of anonymity to discuss the sensitive subject. No decisions have been made, the people said, and it is possible Biden opts to do nothing at all. Pardons are historically afforded to those accused of specific crimes –- and usually to those who have already been convicted of an offense — but Biden’s team is considering issuing them for some who have not even been investigated, let alone charged. The president could, if he chose, issue blanket pardons to specific people whom Trump and his allies have threatened to punish. Or he could pardon a broad class of people — not unlike pardons issued to those convicted of federal marijuana offenses or those ensnared in the “don’t ask, don’t tell” military policies. Some worry that Trump and his allies, who have talked of enemies lists and exacting “retribution,” could launch investigations that would be reputationally and financially costly for targeted people even if they don’t result in prosecutions. The door has already been opened, given that Biden has extended a broad , who was convicted and pleaded guilty in tax and gun cases. Biden explained that decision by saying he believed the prosecution of his son had been poisoned by politics. White House press secretary Karine Jean-Pierre has said Biden plans additional pardons before leaving office though she would not elaborate on the process. She repeatedly referenced “changing factors” that motivated the president to pardon his son despite promising he wouldn’t. She said Republicans have continued to try to see Hunter Biden investigated for an array of alleged offenses, a rationale that could support additional pardons for Biden aides and allies. It was two weeks ago that one of the president’s closest allies in Congress, Rep, Jim Clyburn of South Carolina, encouraged Biden to pardon his son Hunter. The morning after that conversation, Clyburn told Biden’s staff that he believed the president should also pardon those being targeted by Trump. “I was very forceful in my discussions with him about what I thought he ought to do regarding his son,” Clyburn said Friday. “But I also told them that I thought he ought to go even further, because all the noise about Jack Smith and Liz Cheney and Doctor Fauci and all of that.” Trump for his efforts to overturn the 2020 presidential election and for accusations he hoarded classified documents at his home. , was the vice chairwoman of the congressional committee investigating the Jan. 6, 2021, Capitol insurrection and campaigned for Vice President Kamala Harris. All have raised the ire of Trump. Clyburn said he told Biden’s team, only half jokingly, that because the Supreme Court has already said that the president has certain immunities, “let’s give that same immunity to Jack Smith for carrying out his duties and to, Doctor Fauci, Liz Cheney, they were carrying out their duties.” Among those mentioned publicly for possible presidential pardons, there are different sentiments on whether pardons would even be wanted. Former House Speaker Nancy Pelosi supported the president’s move to pardon his son, but has been silent on the speculation that Biden is considering additional pardons for her or others. A top Pelosi ally, Rep. Adam Schiff, the Democratic congressman who led Trump’s first impeachment, has panned the idea of pardoning Biden’s allies. He says “the courts are strong enough to withstand” the worst of Trump’s threats. “I don’t think a preemptive pardon makes sense,” the incoming senator told NPR recently. “I would urge the president not to do that. I think it would seem defensive and unnecessary,” Schiff said. Democratic Rep. Jamie Raskin, who was the lead manager on Trump’s second impeachment, on the charge of inciting the Jan. 6, 2021, insurrection at the Capitol, said members of Congress already are protected by the speech and debate clause in the Constitution, which protects them prosecution for participating in their legislative duties. Raskin said figures like Mark Milley, the former chairman of the Joint Chiefs of Staff, , Trump’s former White House chief of staff, would similarly be protected by the First Amendment. But Raskin said the question is, “Should they go through the criminal investigation and prosecution for not doing anything wrong? I think that’s why this whole issue has erupted.” Raksin added that with Trump promising to pardon hundreds of people who assaulted police officers on Jan. 6th, “I can hardly fault President Biden for exploring the use of the pardon to protect people from a fraudulent and unjust prosecution.” House Democratic Leader Hakeem Jeffries said he’s had no conversations with the White House regarding any preemptive pardons for current or former members of Congress. ___ Associated Press Writer Kevin Freking contributed to this report.

WhatsApp has rolled out a controversial change to its messaging interface, replacing the classic "typing..." message with a dynamic animated speech bubble. According to Daily Mail, the update, which users say arrived with little notice, has sparked frustration among many, who find the new feature distracting and unnecessary. The familiar "typing..." indicator, which used to appear at the top of chats, is now replaced by a moving chat bubble below the last message. While the change may seem subtle, some users are already voicing their discontent. On social media, complaints have poured in, with many likening the new feature to the typing animation seen in Apple’s iMessage, calling it "annoying" and "unhelpful." One user even said the animation "purposely gives me anxiety." Despite the backlash, the update is expected to be available to all WhatsApp users in the coming days, signalling another shift in the app’s design—though not everyone is convinced it improves the experience.Rep. Michelle Steel appears to concede to Derek Tran in the 45th congressional district race

NASSAU, Bahamas (AP) — Scottie Scheffler birdied every hole but the par 3s on the front nine at Albany Golf Club on Friday and finished his bogey-free round with an 8-under 64 that gave him a two-shot lead in the Hero World Challenge. Two months off did nothing to slow the world's No. 1 player. Scheffler already has eight victories this year and is in position to get another before the end of the year. Scheffler was at 13-under 131, two ahead of Akshay Bhatia (66) and Justin Thomas (67), both of whom had to save par on the 18th hole to stay in range going into the weekend. Scheffler started with a lob wedge to 2 feet for birdie and never slowed until after he went out in 29 to seize control of the holiday tournament against a 20-man field. Scheffler cooled slightly on the back nine, except it didn't feel that way to him. “Front nine, just things were going my way. Back nine, maybe not as much,” Scheffler said. “A couple shots could end up closer to the hole, a couple putts go in, just little things.” Asked if he felt any frustration he didn't take it lower — he once shot 59 at the TPC Boston during the FedEx Cup playoffs — Scheffler sounded bemused. “I think in this game I think a lot of all y’all are looking for perfection out of us,” he said. “Today I shot 8 under on the golf course, not something I hang my head about. A lot of good things out there — clean card, bogey-free, eight birdies. Overall, I think I'm pretty pleased.” Thomas felt his 67 was stress-free, particularly the way he was driving the ball. The wind laid down again, rare for the Bahamas, though it is expected to pick up on the weekend. Thomas wasn't concerned to see Scheffler get off to a hot start, especially with three par 5s on the front nine and a short par 4 that at worst leaves a flip wedge to the green. “You literally can birdie every hole as soft as the greens are,” Thomas said. “He's a great player, a great wedge player, and you have a lot of birdie holes to start. I'm honestly surprised he only shot 8 under. It's a sneaky course because if you fall asleep on some shots, you can get out of position. But if you're on and focused and really in control of everything — like these last two days with no wind — you can just make so many birdies.” Ryder Cup captain Keegan Bradley had a 67 and was four shots behind. No matter how benign the conditions, it wasn't always easy. Cameron Young, who opened with a 64 for a two-shot lead, followed with a 75 despite making five birdies. That included a double bogey on the final hole when his approach tumbled down the bank into the rocks framing the lake that goes all the way down the 18th hole. Patrick Cantlay was trying to keep pace playing alongside Scheffler, but he had three bogeys over the final seven holes and fell seven shots behind with a 71. The tournament, hosted by Tiger Woods, is unofficial but offers world ranking points to all but the bottom three players because of the small field. It's the weakest field in 25 years, but Scheffler at No. 1 gives it enough cachet. He is the first player since Woods in 2009 to start and finish a year at No. 1 in the world. And even after a layoff — giving him time to tinker with a new putting stroke — it looks like it might be a while before anyone changes that. AP golf: https://apnews.com/hub/golfNutanix Announces Proposed $750 Million Convertible Senior Notes Offering

Mohamed Salah’s landmark goal pulls Liverpool clear in Champions LeagueWASHINGTON — Democrats on the Senate Judiciary Committee highlighted Tuesday the costs and human toll of President-elect Donald Trump’s stated plans to deport all undocumented immigrants, while Republicans sought to limit some of those concerns. Chair Richard J. Durbin, D-Ill., said in his opening remarks the estimated 13 million undocumented immigrants in the United States fill every sector of American society. “It was an undocumented worker who was watching your grandchild this morning at the daycare center, an undocumented worker who walked carefully with your mother back to her room after breakfast, so she didn’t fall down,” Durbin said. “It was an undocumented worker with that leaf blower in your front yard over the weekend.” Democrats held the hearing as a kind of last stand for their views on immigration in the waning days of their majority in the Senate. They invited among their witnesses one of the undocumented immigrants known as Dreamers, who were brought to the U.S. as children and raised and educated here, yet face uncertain futures. Foday Turay, an assistant district attorney at the Philadelphia District Attorney’s Office, said during his opening statement the mass deportations currently planned would be devastating if they include immigrants like him. “Mass deportation hurts all of us, our family, our community and our society,” Turay said. “We owe it to ourselves and to our country to reject mass deportation and look for a solution for Dreamers whose lives have become deeply rooted in the country and strengthen our borders.” Durbin referenced a recent interview Trump gave on “Meet the Press,” when he said he’d be open to a legislative solution for the Dreamers, as among the “positive things” coming from the president-elect. “He really challenged us on the Democratic side to work with him when he came to the Dreamers,” Durbin said. “I accept the challenge. Name the time and place, Mr. President. I’ll be there.” Republicans on the committee, for their part, signaled an openness to working with Democrats on the solution for the Dreamers, although it appears it would have to be a component of a larger immigration scheme. Sen. Lindsey Graham, R-S.C., suggested he’d be open to solution that would include them: “As to the Dreamers, hopefully we can find a solution to that problem.” “I think President Trump is pretty clear about DACA, but what do we tell the kids who’ve been brought here in the last year who are 7 years old?” Graham added. “Do you ever break this chain? So I’m hoping, Mr. Chairman, that once we regain control of our border and try to shut down the poisoning of America, we can have a logical, fractional discussion about Dreamers and others.” “But until we control that border, until we get control of the crime coming into this country, into the poison of America, that discussion cannot happen,” Graham said. Graham said Republicans are preparing a “transformative” border security funding bill, which by some reported estimates may total as much as $85 billion. Republicans at the hearing seemed to downplay the scope of the deportation effort, making the case that immigrants convicted of crimes should be a priority for removal, as well as undocumented immigrants who had received their final deportation orders after having their cases adjudicated in immigration court. The senators heard one estimate that the cost of Trump’s deportation plan could be as high as an annual cost of $88 billion, for the hiring and infrastructure needed to deport 1 million people a year, and a mass deportation campaign would lead to a loss in total GDP of 4.2 to 6.8 percent at minimum, as much as the Great Recession. Aaron Reichlin-Melnick, senior fellow at the American Immigration Council, delivered those numbers to the committee as part of his testimony urging Congress to advance legislation creating pathways to citizenship instead of mass deportation. Sen. Thom Tillis, R-N.C., said he is “part of a group of people here who ... believes there should be a path for Dreamers,” but that advocates such as Reichlin-Melnick were personally responsible for the failure of Congress to enact protections. “You cause people to go into their corners and get nothing done,” Tillis said. “That is why Chair Durbin has not been able to fulfill the promise on Dreamers every single year he’s tried for the last 20 because people like you make it impossible to have a — let me finish, and then I’ll let you speak, as long as the chair wants to — have a rational discussion about it, because if we don’t secure the border, I can’t get a path to citizenship for the DACA population.” Tillis’ time expired and he exited the committee hearing before Reichlin-Melnick had a chance to respond. After the hearing, Reichlin-Melnick said among the things he would like to say in response to Tillis was the importance of finding a solution that enables a “rising tide to lift all boats.” “If the choice is rupture the social fabric by deporting 13 million people or work to build greater prosperity, that’s what we should be doing,” Reichlin-Melnick said. Some Democrats on the committee made comments seeking common ground, asserting the 2013 immigration reform measure or the bipartisan border bill currently pending before Congress would be good starting points. Neither have any serious prospects with Republicans in control of the White House and Congress. The bipartisan border bill has been declared dead even by its supporters. Sen. Amy Klobuchar, D-Minn., brought up the bipartisan legislation, which was supported by Sen. James Lankford, R-Okla., as a legislative solution for immigration that should be revisited. “Hopefully that can be at least a starting point for discussing it, even though it didn’t go anywhere last year,” Klobuchar said. Klobuchar pointed to proposals on “path to citizenship for Dreamers, on doing something for the temporary status people, on looking at people who have not committed crimes and what we can do to make sure our workforce is strong, I think there is a path here and I’m just continuing to focus on where we can go.” ©2024 CQ-Roll Call, Inc., All Rights Reserved. Visit cqrollcall.com. Distributed by Tribune Content Agency, LLC.

Sitting on the floor outside of Silver Creek High School’s weight room, Ibrahim Kaboré lit up while talking about his journey from Burkina Faso to wrestling hater to wrestling state qualifier. His move from the African country in 2018 was anything but easy, but he was lucky to have a friend pulling him forward from middle school into his senior year with the Raptors. Stephen Thomas, his fellow wrestler, tapped into Kaboré’s competitive side, convincing him to join track, then football, and ultimately wrestling. “If it wasn’t for him, I don’t even think I would have picked up sports. He might not admit it, but he was one of my first friends I made in America,” Kaboré said. “I did not know anything about wrestling. I didn’t even know what wrestling was. I was like, ‘Oh, okay, I’ll try it out.’ I mean, he told me football was going to be fun and football was kind of fun. “Our first day of practice (freshman year), it felt like the worst thing I’ve done in my life. I don’t know what it was. My whole body, my lungs were burning. I almost cried as I was walking out of the wrestling room. It was really hard. If that’s what I have to go through every day, I don’t think I want to do this.” His first trial in the sport ended in error, but Thomas wouldn’t let it go. Over the course of the next year, he wore Kaboré down. “Well, see, I’m really persistent,” Thomas said. “I would come over to his house. We would practice doing athletic stuff because we like trying to do back flips. And then every 10 minutes, I’d be like, ‘Hey, you should definitely join wrestling.’ ‘Oh, yeah, wrestling is pretty cool.’ ‘Actually, you saw this move this guy, the fighter, did in here? Oh, that’s all wrestling right there.’ ‘You can unlock all these cool things if you just do wrestling.’” It wasn’t the only thing he helped his friend learn to love — and survive. “I taught him how to run. One day we were just racing, and, well, I find out he can’t run for nothing. He was pretty athletic and looked insane, but he couldn’t run. It was weird. It was like it was the first time he’s ever ran in his life. He kind of went off like this.” Thomas paused to demonstrate, running down the hall outside the gym with his arms flailing. “His arms weren’t coordinated, and he ended up tripping and almost knocking himself out on a brick wall. I had him walk through the steps, and after a while, he got pretty good. He found his own rhythm. He learned how to run himself. He probably doesn’t even remember me teaching him all that wrestling, just knowing that he fell and damn near lost his life.” Now, as Kaboré enters his third and final season on the mats, he’s preparing to take on another challenge — competing in the 215-lb. weight class at just 190 lbs. Last season, the grappler paved his own path toward the Class 4A state tournament at Ball Arena, but met a swift exit. He took it all in stride, focusing on just four moves to push him to a 23-16 record. He said that he practiced the double blast, single leg, sweep single and high seat until it all became second nature. He opened this season with a loss to Holy Family’s Camden Austin, but quickly corrected course to defeat opponents from Greeley West, Fossil Ridge and Eaglecrest. The hardship only hardened him for his athletic prowess on the mat. When Kaboré first arrived in the U.S., as only a middle schooler, certain things struck him as odd that he’d never thought about before. Waking up to eat breakfast, and later lunch, was foreign to a child that could only rely on dinner every day. In Burkina Faso, his large, extended family lived in a compound-style house. Here, they lived in an apartment, where his father often turned on Moana to help his kids learn English. Kaboré thanked the island-themed kid’s movie for helping him assimilate a bit faster to American life, just as one of its characters, Maui, said “you’re welcome” right back. That doesn’t mean it was an easy transition to start. “It felt like I was an outcast because I couldn’t express myself,” Kaboré said. “I could just look at people and maybe give head shakes or maybe say ‘hello,’ ‘thank you.’ That was all I could say, so it was definitely pretty hard.” Kaboré was fluent in French and Dyula, a West African language spoken primarily in Burkina Faso, Mali and the Republic of Côte d’Ivoire. He said he often had to watch the way his teachers’ mouths moved to decipher what they were saying, and struggled in his schooling. But as his English improved, so did his confidence. The shy, reserved middle schooler turned into a high schooler so social and confident that he had to teach his wrestling coach, Chris Blair, how to say “shut up” in Dyula. Blair has been with Kaboré from the beginning of his high school athletics experience. “In track, I just thought that he just didn’t want to listen,” Blair explained. “And then as I got to know him over the summer, it was like, no, he does listen. He just doesn’t know what we’re saying. For me, it just took me understanding that he just needs things said multiple times, different ways, and just kind of work with him on it.” Kaboré said that in his final season, he’s working toward placing as high as he can at the state tournament come February. He knows it won’t be easy battling guys 25 lbs. heavier than him, but if his life has taught him anything, it’s that he knows how to rise above the most challenging circumstances. The Raptors, in general, are better off for it. “He’s an awesome leader,” Blair said. “He’s gone through so much to get to the point where he’s at — language barrier, new sport, new country. But he’s one of the best leaders that we have, not only in wrestling, but he was awesome in football. He’s always smiling, always positive, always loving to be engaged with the group.” View a list of Prep sports and high school teams we cover.December 10, 2024 This article has been reviewed according to Science X's editorial process and policies . Editors have highlightedthe following attributes while ensuring the content's credibility: fact-checked proofread by Ute Kehse, Carl von Ossietzky-Universität Oldenburg In April 2021, two tropical cyclones, Seroja and Odette, collided in the Indian Ocean northwest of Australia. Two researchers from the University of Oldenburg have now studied how this rare phenomenon affected the ocean. According to their case study, the rendezvous caused an unusual cooling of the surface water and an abrupt change in the direction of the combined storm. Since the frequency and intensity of tropical cyclones are increasing as a result of global warming, it is possible that such encounters—and thus more extreme air-sea interactions—will become more frequent in the future, they conclude. Tropical cyclones (TCs) not only whip up air masses in the atmosphere, they also churn up water masses in the areas of the ocean that are in their path. When two cyclones collide and merge, these interactions between the ocean and the atmosphere can intensify considerably, as Prof. Dr. Oliver Wurl and Dr. Jens Meyerjürgens from the University of Oldenburg report in a paper published in the journal Tellus A: Dynamic Meteorology and Oceanography . The two researchers analyzed the encounter between two relatively weak tropical cyclones in the Indian Ocean in 2021, TC Seroja and TC Odette, and found that effects occurred that have otherwise only been observed with much stronger cyclones. Since the frequency and intensity of tropical cyclones is increasing as a result of global warming, this type of convergence—and the resulting extreme interactions between air and sea—could become more frequent in the future, the study concludes. The two tropical cyclones Seroja and Odette came together north-west of Australia in April 2021. To investigate the effects of this unusual rendezvous on the ocean, Wurl and Meyerjürgens combined satellite data and measurements obtained from ARGO floats and autonomous drifters with numerical modeling. These sources provided the researchers with information about factors such as salinity and water temperatures between the sea surface and depths of up to 2,000 meters as well as data about upward and downward (vertical) flow velocities. In addition to these data, they analyzed upward and downward (vertical) flow velocities using data from numerical models. The encounter between the two cyclones lasted for around a week. On 6 April they came within approximately 1,600 kilometers of one another. "Seroja first of all stalled the smaller cyclone Odette and then merged with it three days later," reports Wurl, who heads the research group Processes and Sensing of Marine Interfaces at the University of Oldenburg's Institute for Chemistry and Biology of the Marine Environment in Wilhelmshaven. After the two cyclones merged, TC Seroja abruptly changed course by 90 degrees on 9 April. "This chain of events not only influenced weather patterns but also triggered a previously unobserved interaction with the ocean underneath," Wurl explains. Discover the latest in science, tech, and space with over 100,000 subscribers who rely on Phys.org for daily insights. Sign up for our free newsletter and get updates on breakthroughs, innovations, and research that matter— daily or weekly . The analysis showed that sea-surface temperatures dropped by 3°C as an after-effect of the merging of the cyclones, and deep, cold water masses were churned upwards towards the surface from a depth of 200 meters in a process known as "upwelling." The cooling effect was "exceptionally high" in relation to the cyclones' intensity, the researchers observed. The highest wind speeds of around 130 kilometers per hour were reached on 11 April, after the merging of the cyclones, and corresponded to Category 1 on the Hurricane Scale. The observed cooling and the depth of the upwelling, on the other hand, were of a scale observed in Category 4 or 5 hurricanes. Wurl and Meyerjürgens were particularly surprised by the strength of the upwelling: there were periods when the deep-water masses rose to the sea surface at a speed of up to 30 meters per day. By comparison, the typical upward velocity of the ocean is only between 1 and 5 meters per day. In this specific case, a downward velocity of the ocean was observed shortly before the cyclones merged. "Thanks to satellite technology and autonomous deep-sea ARGO floats, we were able to demonstrate how the rotation of the cyclones transports cold water from the depths of the ocean to the surface," says marine scientist Meyerjürgens. Although encounters between tropical cyclones during their one to two-week lifespan have been rare to date, according to climate models , the number and intensity of tropical cyclones is likely to increase as a result of global warming—and by extension also the likelihood of full-blown hurricane-force cyclones colliding. This could result in "the most extreme interactions between the ocean and the atmosphere," the authors of the paper write. The fact that the merging of two cyclones can lead to an abrupt change of course also makes it more difficult to predict how they will behave afterwards. Wurl also points to another important consequence: "As a result of the interactions of a cyclone with the ocean and the upwelling of cold, deep water, the ocean absorbs additional heat from the air and then transports it to higher latitudes —a crucial process that influences the climate worldwide." In addition, cyclones also convert thermal energy into mechanical energy which they then transport to higher latitudes as they progress. The two scientists will be taking part in an expedition with the research vessel METEOR in the Mediterranean and subtropical Atlantic next year, during which they plan to further investigate these interactions and the connection with extreme weather events. More information: Oliver Wurl et al, Intense Cooling of the Upper Ocean with the Merging of Tropical Cyclones: A Case Study in the Southeastern Indian Ocean, Tellus A: Dynamic Meteorology and Oceanography (2024). DOI: 10.16993/tellusa.4083 Provided byCarl von Ossietzky-Universität Oldenburg

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