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37 Firms Stake N286bn Investment Worth In Nigeria Economy Q3, 2024 – NIPCPreview: Barnsley vs. Wigan Athletic - prediction, team news, lineupsScientists literally are shining a light on cancer cells’ energy centers to damage these power sources and trigger widespread cancer cell death. In a new study” ” in , researchers combined strategies to deliver energy-disrupting gene therapy using nanoparticles manufactured to zero in only on cancer cells. Experiments showed the targeted therapy is effective at shrinking glioblastoma brain tumors and aggressive breast cancer tumors in mice. The team says it overcame a significant challenge to break up structures inside these cellular energy centers (mitochondria) with a technique—mLumiOpto—that induces light-activated electrical currents inside the cell. “We disrupt the membrane so mitochondria cannot work functionally to produce energy or work as a signaling hub. This causes programmed cell death followed by DNA damage. Our investigations showed these two mechanisms are involved and kill the cancer cells,” said co-lead author Lufang Zhou, PhD, professor of biomedical engineering and surgery at The Ohio State University. “This is how the technology works by design.” Zhou collaborated on the research with co-lead author , PhD, professor of chemical and biomolecular engineering at Ohio State, who developed the particles used to precisely deliver the gene therapy to cancer cells. Zhou and Liu are also both investigators in the Ohio State University Comprehensive Cancer Center. Mitochondria have been considered an attractive anti-cancer therapeutic target for years, but their impermeable inner membrane complicates these efforts. Zhou’s lab cracked the code five years ago by figuring out how to exploit the inner membrane’s vulnerability—an electrical charge differential that keeps its structure intact and functions on track. “Previous attempts to use a pharmaceutical reagent against mitochondria targeted specific pathways of activity in cancer cells,” he said. “Our approach targets mitochondria directly, using external genes to activate a process that kills cells. That’s an advantage, and we’ve shown we can get a particularly good result in killing different types of cancer cells.” Zhou’s earlier cell studies showed the mitochondrial inner membrane could be disrupted by a protein that creates electrical currents, and researchers activated that light-induced protein with a laser. In this new work, the team created an internal source of light, which was critical to translating the technology for clinical use. The strategy involves delivering genetic information for two types of molecules: a light-sensitive protein known as CoChR that can produce positively charged currents, and a bioluminescence-emitting enzyme. Packed into an altered virus particle and delivered to cancer cells, the proteins are produced as their genes are expressed in mitochondria. A follow-up injection of a specific chemical turns on the enzyme’s light to activate CoChR, which leads to mitochondrial collapse. The other half of the battle is ensuring this therapy does not interfere with normal cells. Liu’s lab specializes in targeted anti-cancer therapy development. The foundation for the delivery system in this work is the well-characterized adeno-associated virus (AAV) engineered to carry genes and promote their expression for therapeutic purposes. The team refined the system to enhance its cancer specificity by adding a promoter protein to drive up expression of the CoChR and bioluminescent enzyme only in cancer cells. The researchers also manufactured the AAV using human cells that encased the gene-packed virus inside a natural nanocarrier resembling extracellular vesicles that circulate in human blood and biological fluids. “This construction assures stability in the human body because this particle comes from a human cell line,” Liu said. Finally, the researchers developed and attached to the delivery particle a monoclonal antibody designed to seek out receptors on cancer cell surfaces. “This monoclonal antibody can identify a specific receptor, so it finds cancer cells and delivers our therapeutic genes. We used multiple tools to confirm this effect,” explained Lin. “After constructing AAVs with a cancer-specific promoter and a cancer-targeting nanoparticle, we found this therapy is very powerful to treat multiple cancers.” Experiments in mouse models showed the gene therapy strategy significantly reduced the tumor burden compared to untreated animals in two fast-growing, difficult-to-treat cancers: glioblastoma brain cancer and triple negative breast cancer. In addition to shrinking the tumors, the treatment extended survival of mice with glioblastomas. Animal imaging studies also confirmed the effects of the gene therapy were limited to cancer tissue and were undetectable in normal tissue. Results further suggested that attaching the monoclonal antibody had the added benefit of inducing an immune response against cancer cells in the tumor microenvironment. The team is studying additional potential therapeutic effects of the mLumiOpto in glioblastoma, triple negative breast cancer and other cancers. Ohio State has submitted a provisional patent application for the technologies.
Gwalior (Madhya Pradesh): Asia's first Geo Science Museum was inaugurated by Vice President Jagdeep Dhankhar and Madhya Pradesh CM Mohan Yadav on Sunday. During the program, Governor Mangubhai Patel, Assembly Speaker Narendra Singh Tomar, MP Bharat Singh Kushwaha, Ministers like Jyotiraditya Scindia, Tulsiram Silavat, Satish Chandra Dubey and others were present. "महाराजा जीवाजीराव सिंधिया ने शिक्षा में रुचि दिखाने का जो मार्ग दिखाया था, उसे हर संस्थान को आगे लेकर जाना है और शिक्षा को accessible बनाने में अपना योगदान देना है।" - माननीय उपराष्ट्रपति श्री जगदीप धनखड़ जी @VPIndia #JiwajiUniversity pic.twitter.com/d77P4S3NeD The Museum was established in the heritage building Victoria Market, Gwalior, a beautiful building of Maharaj Bade, which has now been named Geo Science Museum. आज, ग्वालियर के विक्टोरिया मार्केट में बनकर तैयार हुए 'जियो साइंस म्यूजियम' का लोकार्पण, देश के माननीय उपराष्ट्रपति श्री जगदीप धनखड़ जी के कर कमलों से हुआ। अब ग्वालियर आने वाले पर्यटक, धरती की उत्पत्ति से लेकर भूविज्ञान के क्षेत्र से जुड़ी सभी जानकारी संग्रहालय के माध्यम से... pic.twitter.com/65BafhgaGb Two galleries have been made in this museum. The first gallery will be focused on the Evolution of Earth. It has information regarding the geology, including how the Earth came into its original form and what are the elements from which Earth is made up of, how earth actually looks like. Also, how lava is formed inside the earth and how mountains are formed due to volcanic eruption. Visitors will also be be able to experience earthquakes. Apart from this, there is also description about the atmosphere and ocean. All this has been displayed very well with light effects and modern mechanical technology. Second gallery will focus on Evolution of Life in which information related to the birth of the Earth, the era of dinosaurs, development of human race and human civilization and the universe. In the museum, valuable objects including dinosaur eggs are available for tourists to witness. The description of the change in the lifestyle of human civilization will be worth seeing for the visitors.
Uttar Pradesh science and technology minister Anil Kumar and minority welfare state minister Danish Azad Ansari extended a formal invitation to Jammu and Kashmir Lieutenant Governor Manoj Sinha for the upcoming Mahakumbh 2025 in Prayagraj during a courtesy meeting on Sunday. Kumar informed Sinha that the historic event will take place from January 13 to February 26, 2025. Kumar urged Sinha to grace the occasion. Sinha accepted the invitation, saying the Mahakumbh is a special occasion that unites India’s pluralistic society and provides a global platform to showcase the richness of Indian culture. Highlighting the unique aspects of the mega religious, Kumar said the event will be managed with cutting-edge technology and sustainable practices. Comprehensive arrangements are being made to meet every need of the pilgrims and tourists alike. The entire area will be integrated with digital mapping to provide easy navigation and information to pilgrims, he added. Minister Ansari said, “The Mahakumbh 2025 is a symbol of the cultural and spiritual heritage of not just Uttar Pradesh but the entire nation.” Hindustan Mahakumbh Conclave: Historic event will play key role in making U.P. trillion-dollar economy: Maurya
It’s a big and bitter surprise to discover that Marielle Heller’s new film, “Nightbitch,” is, for the most part, excruciating to watch. Heller made two of the best movies of recent years, “ Can You Ever Forgive Me? ” and “ A Beautiful Day in the Neighborhood ,” yet this new one has few of their virtues. Those films are energized by a sense of sincere and fervent curiosity. Heller seemingly can’t get enough of her main characters; she observes and listens to them with the tenacity of an investigative journalist, and creates a visual style to match their wide-ranging discourse. In “Nightbitch,” Heller gives the impression of knowing exactly what she wants to say, with the result that she turns her characters into mouthpieces and films them with little sense of discovery. Coming from such a probing director, the new work is a disappointment, and yet there’s something diagnostically very interesting about the movie’s failings. “Nightbitch,” based on a novel by Rachel Yoder , centers on a family of three in a comfortable suburb. The family members are unnamed; Amy Adams stars as an artist and former gallery employee who now stays home with her toddler son, whom she calls Baby. Her husband (Scoot McNairy) has a job that requires long hours and frequent travel; he mentions writing reports in a hotel room late at night, but that’s as much as is divulged. (In the novel, he’s an engineer, they live in a “small Midwestern town,” and she used to run a community-based gallery, but the characters are likewise unnamed.) Baby is a poor sleeper, so the mother has to tend to him day and night while also running the household. She seems to have no friends; she grudgingly brings Baby to the local library for a “Book Babies” parent-and-child reading and sing-along session, but she has only contempt for the other suburban mommies, whom she considers unintellectual, unstylish, uninspired, unamusing. Isolated and exhausted, the mother is frustrated, and miserable. In social situations, she feels pressure to wax lyrical about the joys of motherhood, even as she fantasizes about speaking her mind or lashing out physically. But the mother doesn’t snap; instead, at night, she turns into a dog. She finds herself growing sharp incisors, unexpected fur, a tail, and six extra nipples, and developing a heightened sense of smell, cravings for meat, an urge to hunt small animals, and an irresistible attractiveness to the neighborhood’s stray dogs. (She also refers to herself as Nightbitch, as in the novel.) At first, Nightbitch assumes she’s dreaming, but then she awakens to discover that she has killed a rabbit—and then the family’s cat. The first hint of an aesthetic problem with “Nightbitch” is when Adams’s character calls her toddler “Baby.” Soon it became obvious that the main characters’ namelessness is not just a question of omission—plenty of secondary and incidental characters are named—but a part of a deliberate choice to de-characterize. For instance, there’s no indication of the couple’s interests. They don’t talk except about basic practicalities; he plays a video game (which one?); the couple sit and watch something on TV (what?); when she’s home with Baby, there’s no radio on, no podcast, no music playing, nothing that suggests any trace of identity. She is reduced to her function as a mother and, occasionally, as a wife. That’s the point, of course: stripped by her unending domestic duties of everything that makes her who she is, Nightbitch undergoes a feral transformation as her suppressed rage erupts. But that’s an elevator pitch, not an experience. The film’s premise is rendered abstract, mapped out with a quasi-mathematical rigor that merely elides the specifics on which the drama depends. It’s as if the story were plotted on a graph, with one axis labelled “money” and another one labelled “communication.” Early on, Nightbitch tries to tell her husband about her frustrations and her desire to change things around by getting a part-time job. He shuts her down with the declaration that “you know, the math doesn’t totally add up”—that she’d earn less than child care would cost. But what are those numbers? And what are the other relevant numbers? How much does he make? How expensive is their comfortably big house? How much do they owe, and what are their savings? Presumably, if he were earning enough to pay for day care or a babysitter, “Nightbitch” would be a very short movie. Lack of money is an underlying stress that the film leaves unexpressed and unexplored. It’s telling, therefore, that there isn’t any other purchase or payment in the movie that appears to cause a shadow of a doubt or a second thought. Even when—spoiler alert—a change in the couple’s circumstances entails a sharp increase in expenses, it’s neither discussed nor sweated over. It’s no problem at all. The movie’s silences about money are matched by wider-ranging silences, which concern the other axis—communication—on which the story is graphed. Nightbitch repeatedly makes clear that the decision to leave her gallery job and her artistic calling and to stay home with Baby was her own—that she was eager to do it. What’s unclear is the couple’s decision to leave the city and move to the suburbs, what they anticipated the financial consequences to be, what their other options were, what experiences and desires prompted Nightbitch to make this choice. She also accuses her husband of having accepted her choice too rapidly, when pushing back would have affirmed the importance of her career and her art. What are their politics? What made them think that they’d find happiness in the suburbs? Nightbitch, it’s understood, grew up outside the city, and her mother—an accomplished singer who gave up her own career to raise children— also underwent something like the nocturnal transformations that Nightbitch now experiences. Has she ever discussed this with her husband? Why does she have no friends to talk with, no one to take into her confidence? She does have her grad-school art-world friends, whom she sees again after a long absence and who, she discovers, are assholes in whom she couldn’t confide at all. Not only do Nightbitch and her husband not talk much now; they seemingly didn’t talk much before Baby came along. They give the impression of having met for the first time on the set when Heller first called “Action.” There’s no loam of shared experience, no sense of a shared life, nothing between them but the silences on which the story depends, and without which, again, the drama would quickly be resolved. There isn’t even much in the way of canine experience—a director who imagined these characters in subjective detail would also have made much more of Nightbitch’s feral adventures. In this regard, as in many others, Heller’s adaptation has bowdlerized Yoder’s novel. (For example, if the movie had dramatized the book’s dénouement, it would likely have rivalled “The Substance” for gonzo spectacle.) The silences of “Nightbitch” regarding money and the blanks regarding inner lives and shared lives make the movie an empty and contrived experience. This a surprise, not only because Heller’s two previous works were so alert and engaged but because the topic of the new one turns out to be one in which she feels a personal stake. I learned about this only by reading my colleague Emily Nussbaum’s recent Profile of Heller , in which Heller speaks about her experience staying home with her young children, while her partner, the filmmaker Jorma Taccone, went on working. At the core of the film’s artistic failings is a paradox—of a deep personal investment and a frozen artistic involvement. The inherent conflict of Nightbitch’s misery and her husband’s practical-minded indifference is a poignant and fruitful subject for a movie, a classic premise for a melancholy melodrama. But the sweetening of the story and the effacing of its details suggest unease and ambivalence about its personal aspects. Directors of great marital melodramas either haven’t had such worries or else have been more at ease with the autobiographical aspects of their art. Nothing suggests that Douglas Sirk was reporting on his home life in “ There’s Always Tomorrow ”; everyone understood that Ingmar Bergman, directing his partner Liv Ullmann, was doing something of the sort in “Scenes from a Marriage.” As for Ida Lupino, she directed an extraordinary marital melodramas, “ The Bigamist ,” from 1953, in which she and Joan Fontaine co-starred as a man’s two wives—soon after, Lupino had divorced Collier Young, the movie’s screenwriter and co-producer, and Fontaine had married him. The marital melodrama, it seems, can flourish with philosophical distance or, conversely, with uninhibited openness or sheer chutzpah—in any case, not with the hedging defensiveness on display in “Nightbitch.” ♦ New Yorker Favorites A man was murdered in cold blood and you’re laughing ? The best albums of 2024. Little treats galore: a holiday gift guide . How Maria Callas lost her voice . An objectively objectionable grammatical pet peeve . What happened when the Hallmark Channel “ leaned into Christmas .” Sign up for our daily newsletter to receive the best stories from The New Yorker .British Columbia business owner Joe Chaput will spend $5,500 a month on security guards during the holiday season and plans on upgrading his store’s video camera system for around $5,000 more. He’s not selling luxury brands or expensive jewels. Chaput sells cheese, and at Christmas, cheese is a hot commodity. He is the co-owner of specialty cheese store les amis du Fromage, with two locations in Vancouver. While cheeselifting is rare in their Kitsilano store, the outlet in East Vancouver is hit in waves, with nothing happening for a month, then three of four people trying to steal their inventory within a week. “Sometimes, you miss it. Sometimes, you catch it. The way shoplifters behave ... they tend to gravitate toward expensive things,” said Chaput. Expensive cheese is on shoplifters’ Christmas list, he said. “They tend to do the classic examples of staying away from customer service and trying to go to a different part of the store so they can be left alone to steal.” Chaput isn’t alone. Police say food-related crimes on are the rise in Canada and as prices climb for items such as cheese and butter, they become lucrative on the black market for organized crime groups, not to mention theft for local resale. Sylvain Charlebois, the director of Dalhousie University’s Agri-food Analytics Lab, said a black market tends to emerge as soon as food prices surge. “Organized crime will steal anything (if) they know they can sell it and so, they probably would have known who their clients are before even stealing anything at all, and that’s how a black market is organized,” said Charlebois. He said he believes there are two categories of people shoplifting — those who do so out of desperation because they can’t afford the food, or organized criminals, profiting from sales on the black market. Mounties in North Vancouver made cheesy headlines when they ran into a man with a cart of stolen cheese in the middle of the night in September. The cheese, valued at $12,800, was from a nearby Whole Foods Store. While the cheese was recovered, it had to be disposed of because it hadn’t been refrigerated. Const. Mansoor Sahak, with the North Vancouver RCMP, said officers believe cheese is targeted because it’s “profitable to resell.” “If they are drug addicts, they will commit further crimes with that or feed their drug habits. It’s a vicious cycle,” said Sahak. Sahak said meat is also a top target for grocery thieves, with store losses sometimes in the thousands. “So, we’re not surprised that this happened,” said Sahak. Police in Ontario have been chasing down slippery shoplifters going after butter. Scott Tracey, a spokesman with Guelph Police Service, said there have been eight or nine butter thefts over the last year, including one theft last December worth $1,000. In October, two men walked into a local grocer and filled their carts with cases of butter valued at $936, and four days later a Guelph grocer lost four cases valued at $958. Tracey said he has looked at online marketplaces and found listings by people selling 20 or 30 pounds of butter at a time. “Clearly, somebody didn’t accidentally buy 30 extra pounds of butter. So, they must have come from somewhere,” said Tracey, I think at this point it appears to be the black market is where it's headed He said the thefts seem to be organized, with two or three people working together in each case. Police in Brantford, Ont., are also investigating the theft of about $1,200 worth of butter from a store on Nov. 4. Charlebois said retailers could invest in prevention technologies like electronic tags, but putting them on butter or cheese is rare. He said up until recently grocery store theft has been a “taboo subject for many years.” Stores didn’t want to talk about thefts because they didn’t want to alarm people but now they feel they need to build awareness about what is “becoming a huge problem,” said Charlebois. Chaput, the cheese store owner, said he had been running the East Vancouver store for 15 years while managing the store in Kitsilano for 30 years, and he loves his customers. “It’s really one of the best parts of our businesses, seeing familiar faces and making new customers. It’s why we come to work, really. Partly it’s the cheese, and partly it’s the people,” said Chaput. He said his strategy to combat would-be thieves is to give them extra customer service to make it harder for them to steal. He admits, however, that the shoplifting causes him stress. “It’s challenging. You’re busy trying to run your business day to day and take care of customers and take care of employees. Having to deal with criminals, just kind of scratches away. It can be a bit exhausting,” said Chaput. Our website is the place for the latest breaking news, exclusive scoops, longreads and provocative commentary. Please bookmark nationalpost.com and sign up for our daily newsletter, Posted, here .
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is gaining on in the lucrative online search market, according to new data released this week. In a recent survey of 1,000 people, 's chatbot was the top search provider for 5% of respondents, up from 1% in June, according to brokerage firm Evercore ISI. drove the most adoption, the firm added in a research note sent to investors. Google still dominates the , but its share slipped. According to the survey results, 78% of respondents said their first choice was Google, down from 80% in June. It's a good business to be a gatekeeper A few percentage points may not seem like much, but controlling how people access the world's online information is a big deal. It's what fuels , which produces the bulk of its revenue and huge profits. Microsoft Bing only has 4% of the search market, per the Evercore report, yet it generates billions of dollars in revenue each year. ChatGPT's gains, however slight, are another sign that Google's status as the internet's gatekeeper may be under threat from generative AI. This new technology is changing how millions of people access digital information, sparking a rare debate about the sustainability of Google's search dominance. OpenAI launched a full for ChatGPT at the end of October. It's also got a this year that puts ChatGPT in a prominent position on many iPhones. Both moves are a direct challenge to Google. (Axel Springer, the owner of Business Insider, has a commercial relationship with OpenAI). ChatGPT user satisfaction vs Google When the Evercore analysts drilled down on the "usefulness" of Google's AI tools, ChatGPT, and Copilot, Microsoft's consumer AI helper, across 10 different scenarios, they found intriguing results. There were a few situations where ChatGPT beat Google on satisfaction by a pretty wide margin: people learning specific skills or tasks, wanting help with writing and coding, and looking to be more productive at work. It even had a 4% lead in a category that suggests Google shouldn't sleep too easy: people researching products and pricing online. Google is benefiting from generative AI Still, Google remains far ahead, and there were positive findings for the internet giant from Evercore's latest survey. Earlier this year, Google released Gemini, a ChatGPT-like helper, and rolled out AI Overviews, a feature that uses generative AI to summarize many search results. In the Evercore survey, 71% of Google users said these tools were more effective than the previous search experience. In another survey finding, among people using tools like ChatGPT and Gemini, 53% said they're searching more. That helps Google as well as OpenAI. What's more, the tech giant's dominance hasn't dipped when it comes to : people looking to buy stuff like iPhones and insurance. This suggests Google's market share slippage is probably more about queries for general information, meaning Google's revenue growth from search is probably safe for now. So in terms of gobbling up more search revenue, ChatGPT has its work cut out. Evercore analyst Mark Mahaney told BI that even a 1% share of the search market is worth roughly $2 billion a year in revenue. But that only works if you can make money from search queries as well as Google does. "That's 1% share of commercial searches and assuming you can monetize as well as Google — and the latter is highly unlikely in the near or medium term," he said. Read the original article onA judge on Monday rejected a request to block a San Jose State women’s volleyball team member from playing in a conference tournament on grounds that she is transgender. The ruling by U.S. Magistrate Judge S. Kato Crews in Denver will allow the player, who has played all season, to compete in the Mountain West Conference women’s championship opening this week in Las Vegas. The ruling comes in a lawsuit filed by nine current players against the Mountain West Conference challenging the league’s policies for allowing transgender players to participate. The players argued that letting her compete was a safety risk and unfair. While some media have reported those and other details, neither San Jose State nor the forfeiting teams have confirmed the school has a trans woman volleyball player. The Associated Press is withholding the player’s name because she has not commented publicly on her gender identity. School officials also have declined an interview request with the player. Crews’ ruling referred to the athlete as an “alleged transgender” player and noted that no defendant disputed that the San Jose State roster includes a transgender woman player. San Jose State will “continue to support its student-athletes and reject discrimination in all forms,” the university said in a statement, confirming that all its student-athletes are eligible to participate under NCAA and conference rules. “We are gratified that the Court rejected an eleventh-hour attempt to change those rules. Our team looks forward to competing in the Mountain West volleyball tournament this week.” The conference did not immediately respond to an email seeking comment. The players filed a notice for emergency appeal with the 10th U.S. Circuit Court of Appeals. Crews said the players who filed the complaint could have sought relief much earlier, noting the individual universities had acknowledged that not playing their games against San Jose State this season would result in a loss in league standings. He also refused a request to re-seed the tournament without the forfeited losses. The judge said injunctions are meant to preserve the status quo. The conference policy regarding forfeiting for refusing to play against a team with a transgender player had been in effect since 2022 and the San Jose State player has been on the roster since 2022 -– making that the status quo. The player competed at the college level three previous seasons, including two for San Jose State, drawing little attention. This season’s awareness of her reported identity led to an uproar among some players, pundits, parents and politicians in a major election year. Crews’ ruling also said injunctions are meant to prevent harm, but in this case, he argued, the harm has already occurred. The games have been forfeited, the tournament has been seeded, the teams have made travel plans and the participants have confirmed they’re playing. The tournament starts Wednesday and continues Friday and Saturday. Colorado State is seeded first and San Jose State, second. The teams split their regular-season matches and both get byes into Friday’s semifinals. San Jose State will play the winner of Wednesday’s match between Utah State and Boise State — teams that both forfeited matches to SJSU during the regular season. Boise State associate athletic director Chris Kutz declined to comment on whether the Broncos would play SJSU if they won their first-round tournament game. Utah State officials did not immediately respond to emails seeking comment. The conference tournament winner gets an automatic bid to the NCAA tournament. San Jose State coach Todd Kress, whose team has not competed in the national tournament since 2001, has said his team has been getting “messages of hate” and that has taken a toll on his players. Several teams refused to play against San Jose State during the season, earning losses in the official conference standings. Boise State and Wyoming each had two forfeits while Utah State and Nevada both had one. Southern Utah, a member of the Western Athletic Conference, was first to cancel against San Jose State this year. Nevada’s players stated they “refuse to participate in any match that advances injustice against female athletes,” without elaborating. Nevada did not qualify for the conference tournament. The nine current players and others now suing the Mountain West Conference, the California State University Board of Trustees and others include San Jose State senior setter and co-captain Brooke Slusser. The teammate Slusser says is transgender hits the volleyball with more force than others on the team, raising fear during practices of suffering concussions from a head hit, the complaint says. The Independent Council on Women’s Sports is funding a separate lawsuit against the NCAA for allowing transgender women to compete in women’s sports. Both lawsuits claim the landmark 1972 federal antidiscrimination law known as Title IX prohibits transgender women in women’s sports. Title IX prohibits sexual discrimination in federally funded education; Slusser is a plaintiff in both lawsuits. Several circuit courts have used a U.S. Supreme Court ruling to conclude that discriminating against someone based on their transgender status or sexual orientation is sex-based discrimination, Crews wrote. That means case law does not prove the “likelihood of success” needed to grant an injunction. An NCAA policy that subjects transgender participation to the rules of sports governing bodies took effect this academic year. USA Volleyball says a trans woman must suppress testosterone for 12 months before competing. The NCAA has not flagged any issues with San Jose State. The Republican governors of Idaho, Nevada, Utah and Wyoming have made public statements in support of the team cancellations, citing fairness in women’s sports. President-elect Donald Trump likewise has spoken out against allowing transgender women to compete in women’s sports. Crews was a magistrate judge in Colorado’s U.S. District Court for more than five years before President Joe Biden appointed him as a federal judge in January.Laurus Bio secures 120 cr investment(All times Eastern) Schedule subject to change and/or blackouts Monday, Dec. 16 COLLEGE SOCCER (MEN’S) 8 p.m. ESPN2 — NCAA Tournament: Vermont vs. Marshall, Championship NFL FOOTBALL 8 p.m. ABC — Chicago at Minnesota 8:30 p.m. ESPN — Atlanta at Las Vegas NHL HOCKEY 8:30 p.m. NHLN — Florida at Edmonton SOCCER (MEN’S) 3 p.m. USA — Premier League: West Ham United at AFC Bournemouth SOCCER (WOMEN’S) Noon FS2 — Final Draw For The UEFA Women’s Euro 2025 The Associated Press created this story using technology provided by Data Skrive TV listings provided by LiveSportsOnTV .
FLORHAM PARK, N.J. (AP) — New York Jets running back Breece Hall could play Sunday at Jacksonville after missing a game with a knee injury. Hall has been dealing with a hyperextension and injured MCL in his left knee that sidelined him last Sunday at Miami. But he was a full participant at practice Friday after sitting out Wednesday and Thursday. Hall was officially listed as questionable on the team's final injury report. “He looks good right now,” interim coach Jeff Ulbrich said. “So it’s promising.” Hall leads the Jets with 692 yards rushing and four touchdown runs, and he also has 401 yards receiving and two scores on 46 catches. A pair of rookies helped New York offset Hall's absence last weekend, with Braelon Allen rushing for 43 yards on 11 carries, and Isaiah Davis getting 40 yards on 10 attempts and scoring his first rushing touchdown. “We’re hopeful and we’ll see how it goes,” Ulbrich said of Hall. The Jets will get star cornerback Sauce Gardner back after he missed a game with a hamstring injury, but New York's secondary appears likely to be without cornerback D.J. Reed because of a groin injury. Reed was listed as doubtful after he didn't practice Thursday or Friday. “It’s been something that’s kind of lingered here and there,” Ulbrich said. “It’s gotten aggravated and then it went away, and then it got aggravated again. So, it’s just dealing with that.” Backup Brandin Echols is out with a shoulder injury, so veteran Isaiah Oliver or rookie Qwan'tez Stiggers could get the start opposite Gardner if Reed can't play. Kendall Sheffield also could be elevated from the practice squad for the second game in a row. Ulbrich said kick returner Kene Nwangwu will be placed on injured reserve after breaking a hand last weekend at Miami. The injury came a week after he was selected the AFC special teams player of the week in his Jets debut, during which he returned a kickoff 99 yards for a touchdown and forced a fumble in a loss to Seattle. “To put him out there with a broken hand, just thought it’d be counterproductive for him and for us as a team, so it unfortunately cuts the season short and what a bright light he was,” Ulbrich said. “What an amazing future I think he has in this league. With saying that, he’s already been a really good player for quite a while, so (it's) unfortunate, but he’ll be back.” Offensive lineman Xavier Newman (groin) is doubtful, while right guard Alijah Vera-Tucker (ankle) and RT Morgan Moses (wrist) are questionable. ___ AP NFL: https://apnews.com/hub/NFL Dennis Waszak Jr., The Associated Press
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