
Lehigh at Idaho — ESPN+ The Associated Press created this story using technology provided by Data Skrive TV listings provided by LiveSportsOnTV .Group of B.C. Conservative MLAs turn on fellow caucus member for backing police board member's resignation
Percentages: FG .356, FT .667. 3-Point Goals: 4-21, .190 (N.Tarke 3-9, Sulaiman 1-3, Hicks 0-1, May 0-2, Williamson 0-6). Team Rebounds: 7. Team Turnovers: None. Blocked Shots: 2 (Lowery, Sulaiman). Turnovers: 12 (Sulaiman 5, N.Tarke 4, Jones 2, Williamson). Steals: 6 (N.Tarke 2, Embeya, Lowery, May, Samb). Technical Fouls: None. Percentages: FG .396, FT .696. 3-Point Goals: 2-12, .167 (Hobbs 2-5, Lawson 0-1, Thomas 0-1, Oliver 0-2, Tabbs 0-3). Team Rebounds: 8. Team Turnovers: None. Blocked Shots: 5 (Martin 2, Simpkins 2, Akitoby). Turnovers: 9 (Martin 3, Simpkins 3, Akitoby, Hobbs, Lawson). Steals: 10 (Simpkins 3, Oliver 2, Tabbs 2, Thomas 2, Lawson). Technical Fouls: None. A_687 (4,250).
Brown-John: Canadian universities, colleges 'overdosing' on foreign students
TORONTO and HAIFA, Israel, Dec. 06, 2024 (GLOBE NEWSWIRE) -- NurExone Biologic Inc. (TSXV: NRX), (OTCQB: NRXBF), (Germany: J90) (" NurExone " or the " Company "), a biopharmaceutical company developing exosome-based regenerative therapies, has announced significant findings from an expanded preclinical study of the potential of its portfolio drug, ExoPTEN, for repairing optic nerve damage. Conducted in collaboration with the Goldschleger Eye Institute at Sheba Medical Center, consistently ranked one of the top ten hospitals in the world 1 , the study builds on previously announced preliminary results 2 on June 28, 2024 and strengthens the suggestion of a promising treatment pathway for glaucoma, the leading cause of irreversible blindness globally 3 . The Optic Nerve Disorders treatment market is expected to grow from 5.54 (USD Billion) in 2023 to 11.5 (USD Billion) by 2032, at a compound annual growth rate (CAGR) of ~8.46% during the forecast period 4 . Researchers utilized a rodent model of optic nerve crush (ONC) to simulate the damage associated with conditions like glaucoma. After inducing injury, ExoPTEN was administrated via direct injection into the eyes. The study expanded on earlier findings which indicated that eyes treated with ExoPTEN regained nearly normal retinal activity, as evidenced by electrical tests. Expanded analyses of the study data showed clear recovery of signal transmission in treated eyes compared to untreated controls, which showed no significant response. Additionally, imaging results by optical coherence tomography (OCT) scans indicates and validates that in all of treated eyes (naïve exosome treatment or ExoPTEN treatment) a successful ONC procedure has been performed (Figure 1). The study also showed that ExoPTEN treatment significantly enhanced the survival of retinal ganglion cells - key neurons responsible for transmitting visual information to the brain. Detailed analysis of retinal flat-mounts confirmed this effect, with treated eyes exhibiting substantially higher counts of these cells compared to untreated or control-treated eyes (Figures 2A and 2B). Dr. Ifat Sher, the lead investigator from the Goldschleger Eye Institute, commented, “the results from this expanded study are extremely encouraging. ExoPTEN demonstrates potential as a treatment that restores functionality and offers neuroprotection. The study shows clear signal recovery, healthier optic nerve structures and preserved retinal ganglion cells. These results suggest that ExoPTEN could fundamentally change how we approach conditions like glaucoma and optic nerve trauma. Encouraged by these results, we are advancing to a larger study with more animals to validate and expand upon these findings.” Dr. Lior Shaltiel, CEO of NurExone, added, “these findings are an important step forward in our mission to develop groundbreaking therapies for regenerative medicine in several indications. ExoPTEN’s ability to repair both the structure and function of the optic nerve highlights its transformative potential for addressing vision loss and improving tens of millions of patient lives.” About NurExone NurExone Biologic Inc. is a TSX Venture Exchange (“ TSXV ”) and OTCQB listed pharmaceutical company that is developing a platform for biologically guided exosome-based therapies to be delivered, minimally-invasively, to patients who have suffered Central Nervous System injuries. The Company’s first product, ExoPTEN for acute spinal cord injury, was proven to recover motor function in 75% of laboratory rats when administered intranasally. ExoPTEN has been granted Orphan Drug Designation by the United States Food and Drug Administration (FDA) and by the European Medicines Agency (EMA). The NurExone platform technology is expected to offer novel solutions to drug companies interested in minimally invasive targeted drug delivery for other indications. For additional information and a brief interview, please watch Who is NurExone? , visit www.nurexone.com or follow NurExone on LinkedIn , X (formerly Twitter) , Facebook or YouTube Dr. Lior Shaltiel Chief Executive Officer and Director Phone: +972-52-4803034 Email: info@nurexone.com Oak Hill Financial Inc. 2 Bloor Street, Suite 2900 Toronto, Ontario M4W 3E2 Investor Relations - Canada Phone: +1-647-479-5803 Email: info@oakhillfinancial.ca Dr. Eva Reuter Investor Relations - Germany Phone: +49-69-1532-5857 Email: e.reuter@dr-reuter.eu Allele Capital Partners Investor Relations - US Phone: +1 978-857-5075 Email: aeriksen@allelecapital.com FORWARD-LOOKING STATEMENTS This press release contains certain “forward-looking statements” that reflect the Company’s current expectations and projections about its future results. Wherever possible, words such as “may”, “will”, “should”, “could”, “expect”, “plan”, “intend”, “anticipate”, “believe”, “estimate”, “predict” or “potential” or the negative or other variations of these words, or similar words or phrases, have been used to identify these forward-looking statements. Forward-looking statements in this press release include, but are not limited to, statements relating to: the results of the Company’s preclinical trials and its suggestion of a promising treatment pathway for glaucoma; the growth of the Optic Nerve Disorders treatment market; the Company expanding to further studies; the Company developing groundbreaking therapies for regenerative medicine in several indications; ExoPTEN having the potential to address vision loss and improve patient lives; and the NurExone platform technology offering novel solutions to drug companies interested in minimally invasive targeted drug delivery for other indications. These statements reflect management’s current beliefs and are based on information currently available to management as at the date hereof. In developing the forward-looking statements in this press release, we have applied several material assumptions, including : the a bility to carry out its pre-clinical trials and realize upon the stated benefits of the pre-clinical trials; the Company’s ability to realize upon the stated potential for exosome-loaded drugs in regenerating or repairing damaged nerves; the Company’s ability to maintain its ongoing commitment to using its ExoTherapy platform to advance the field of regenerative medicine; the Optic Nerve Disorders treatment market continuing to grow as stated; the Company expanding to further studies; the Company developing groundbreaking therapies for regenerative medicine in several indications; ExoPTEN addressing vision loss and improve patient lives; and the NurExone platform technology will offer novel solutions to drug companies interested in minimally invasive targeted drug delivery for other indications. Forward-looking statements involve significant risk, uncertainties and assumptions. Many factors could cause actual results, performance or achievements to differ materially from the results discussed or implied in the forward-looking statements. These risks and uncertainties include, but are not limited to risks related to : the Company’s early stage of development; lack of revenues to date; government regulation; market acceptance for its products; rapid technological change; dependence on key personnel; dependence on the Company’s strategic partners; the fact that preclinical drug development is uncertain, and the drug product candidates of the Company may never advance to clinical trials; the fact that results of preclinical studies and early-stage clinical trials may not be predictive of the results of later stage clinical trials; the uncertain outcome, cost, and timing of product development activities, preclinical studies and clinical trials of the Company; the uncertain clinical development process, including the risk that clinical trials may not have an effective design or generate positive results; the potential inability to obtain or maintain regulatory approval of the drug product candidates of the Company; the introduction of competing drugs that are safer, more effective or less expensive than, or otherwise superior to, the drug product candidates of the Company; the initiation, conduct, and completion of preclinical studies and clinical trials may be delayed, adversely affected or impacted by unforeseen issues; the potential inability to obtain adequate financing; the potential inability to obtain or maintain intellectual property protection for the drug product candidates of the Company; risks that the Company’s intellectual property and technology won’t have the intended impact on the Company and/or its business; the Company’s inability to carry out its pre-clinical trials and realize upon the stated benefits of the pre-clinical trials; the Company’s inability to realize upon the stated potential for exosome-loaded drugs in regenerating or repairing damaged nerves; the Company’s inability to maintain its ongoing commitment to using its ExoTherapy platform to advance the field of regenerative medicine; the Optic Nerve Disorders treatment market decreasing and/or plateauing ; the Company ’s inability to expand into further studies; the NurExone platform technology not offering novel solutions to drug companies interested in minimally invasive targeted drug delivery for other indications ; and the risks discussed under the heading “Risk Factors” on pages 44 to 51 of the Company’s Annual Information Form dated August 27 , 202 4 , a copy of which is available under the Company’s SEDAR+ profile at www.sedarplus.ca . These factors should be considered carefully, and readers should not place undue reliance on the forward-looking statements. Although the forward-looking statements contained in this press release are based upon what management believes to be reasonable assumptions, the Company cannot assure readers that actual results will be consistent with these forward-looking statements. These forward-looking statements are made as of the date of this press release, and the Company assumes no obligation to update or revise them to reflect new events or circumstances, except as required by law. Neither TSXV nor its Regulation Services Provider (as that term is defined in the policies of the TSXV) accepts responsibility for the adequacy or accuracy of this release. 1 https://www.afsmc.org/2024/02/sheba-medical-center-named-a-newsweek-worlds-best-hospital-for-the-6th-consecutive-year/ 2 https://www.globenewswire.com/news-release/2024/06/28/2906122/0/en/NurExone-s-ExoPTEN-Being-Studied-as-Glaucoma-Treatment-for-US-3-4-Billion-Market.html 3 https://www.mdpi.com/1424-8247/17/10/1261 4 https://www.marketresearchfuture.com/reports/optic-nerve-disorders-treatment-market-30051 A photo accompanying this announcement is available at https://www.globenewswire.com/NewsRoom/AttachmentNg/5e682a60-3287-44b2-b7da-08ebed8fa807
Our community members are treated to special offers, promotions and adverts from us and our partners. You can check out at any time. More info Dame Prue Leith has spoken out in support of Gregg Wallace amidst allegations of misconduct, suggesting the TV chef shouldn't be sacked. The beloved Great British Bake Off star weighed in on the controversy with words of wisdom as Wallace faces historical allegations and steps back from his BBC cooking show role. Reportedly accused of harassment and inappropriate behaviour while filming a show, though strongly denied by Wallace's lawyers, Dame Prue still sees no reason for a sacking. On Times Radio, Prue, 84, emphasised the need for due process and advised against rash decisions: "I'm a great believer in due process... He should just stay off social media because he's just digging himself deeper and deeper into a hole because he's too insensitive to understand how offensive it is. But that's his problem, that he's insensitive. He hasn't, that I can see, disobeyed the law." She added: "I don't believe people should be cancelled or sacked. I can see why you would ask somebody to step aside while they investigate things, which I suppose is what they're doing. But I think the tragedy in this is that I bet you Gregg has no idea what he's done wrong." Despite her stance against terminating Gregg's role, Dame Prue Leith concedes that television higher-ups ought to enforce firmer standards on their on-screen talent. She expressed her view to Cathy Newman, asserting: "Yes, very weak. For goodness sake, they can replace Gregg Wallace. They can replace anybody. So they should be tough with their presenters. They should be very clear about whatever the rules are." She added: "I do think they've been weak. But I don't want to say that he should be sacked because I don't know what the crime is," reports the Daily Record . MasterChef staff members and former contestants, including celebrities such as Emma Kennedy and Kirsty Wark, have claimed Wallace made them feel uncomfortable on set. On Wednesday, Gregg's ghostwriter, Shannon Kyle, made accusations against the star when speaking to Victoria Derbyshire on NewsNight. Wallace also faces accusations of making lewd requests to a British Sign Language interpreter, asking them to sign phrases like "big boobs" and "sexy bum" during the BBC Good Food Show at the NEC Arena in Birmingham back in 2012. An attendee recounted an incident to the Guardian, stating: "There was a British Sign Language interpreter there and he wandered over to her at one point and just said: 'Do you have to sign everything I say? ' And she said yes, and then he just started saying, 'big boobs', 'sexy bum' – this sort of thing, in order to get her to sign it. It was like he could control her, I suppose." Gregg is currently facing allegations from 13 individuals across multiple shows spanning 17 years, as reported by BBC News. Many others have since shared their own experiences. Banijay UK, the production company behind the show, stated that Gregg is "committed to fully cooperating throughout the process" during the BBC's investigation. He has stepped down from his role on the show amid the investigation. On Sunday morning, Gregg took to social media to dispute the accusations, claiming they came from "middle-class women of a certain age". This prompted Ulrika to comment that his "ignorance and arrogance knows no bounds". He later issued an apology and announced that he was taking a break from social media.
NEW YORK — He’s one of the most famous corporate leaders in the world, delivering products embraced by billions. But the haters give companies like Mark Zuckerberg’s Meta Platforms something to worry about. In an era when online anger and social tensions are increasingly directed at the businesses that consumers count on, Meta last year spent $24.4 million on guards, alarms and other measures to keep Zuckerberg and the company’s former chief operating officer safe. Some high-profile chief executives surround themselves with security. But the fatal shooting this week of UnitedHealthcare CEO Brian Thompson while he walked alone on a New York City sidewalk has put a spotlight on the widely varied approaches companies take in protecting their leaders against threats. Thompson had no personal security and appeared unaware of the shooter lurking before he was gunned down. And today’s political, economic and technological climate is only going to make the job of evaluating threats against executives and taking action to protect them even more difficult, experts say. “We are better today at collecting signals. I’m not sure we’re any better at making sense of the signals we collect,” said Fred Burton of Ontic, a provider of threat management software for companies. After Thompson’s shooting, Burton said, “I’ve been on the phone all day with some organizations asking for consultation, saying, ’Am I doing enough?’” Since the killing, some health insurers have taken steps to safeguard their executives and rank-and-file workers. Medica, a Minnesota-based nonprofit healthcare firm, said Friday that it was temporarily closing its six offices for security reasons and would have its employees work from home. “Although we have received no specific threats related to our campuses, our office buildings will be temporarily closed out of an abundance of caution,” the company said in a statement. A Medica spokesman said the company had also removed biographical information about its executives from its website as a precaution. UnitedHealth Group, parent of the insurer Thompson led, removed photos of its top executives from its website hours after the shooting, later removing their names and biographies. But well before the attack, some of the biggest U.S. companies, particularly those in the tech sector, were spending heavily on personal and residential security for their top executives. Meta, whose businesses include Facebook and Instagram, reported the highest spending on personal security for top executives last year, filings culled by research firm Equilar show. Zuckerberg “is synonymous with Meta and, as a result, negative sentiment regarding our company is directly associated with, and often transferred to, Mr. Zuckerberg,” the Menlo Park, California, company explained earlier this year in an annual shareholder disclosure. At Apple, the world’s largest tech company by stock valuation, CEO Tim Cook was tormented by a stalker who sent him sexually provocative emails and even showed up outside his Silicon Valley home at one point before the company’s security team successfully took legal action against her in 2022. Cook is regularly accompanied by security personnel when he appears in public. Still, the $820,000 the company allotted last year to protect top executives is a fraction of what other tech giants spent for CEO security. Just over a quarter of the companies in the Fortune 500 reported spending money to protect their CEOs and other top executives. Of those that did, the median payment for personal security doubled over the last three years to about $98,000. In many companies, investor meetings like the one UnitedHealthcare’s Thompson was walking to when he was shot are viewed as very risky because details on the location and who will be speaking are highly publicized. “It gives people an opportunity to arrive well in advance and take a look at the room, take a look at how people would probably come and go out of a location,” said Dave Komendat, president of DSKomendat Risk Management Services, which is based in the Seattle area. Some firms respond by beefing up security. For example, tech companies routinely require everyone attending a major event, such as Apple’s annual unveiling of the next iPhone or a shareholder meeting, to go through airport-style security checkpoints before entering. Others forgo in-person meetings with shareholders. Government health insurance provider Centene Corp. joined that group Thursday, citing the UnitedHealthcare executive’s death in announcing that its upcoming investor day will be held online, rather than in person as originally planned. “But there are also company cultures that really frown on that and want their leaders to be accessible to people, accessible to shareholders, employees,” Komendat said. Depending on the company, such an approach may make sense. Many top executives are little known to the public, operating in industries and locations that make them far less prone to public exposure and to threats. “Determining the need for and appropriate level of an executive-level protection program is specific to each organization,” said David Johnston, vice president of asset protection and retail operations at the National Retail Federation. “These safeguards should also include the constant monitoring of potential threats and the ability to adapt to maintain the appropriate level of security and safety.” Some organizations have a protective intelligence group that uses digital tools such as machine learning or artificial intelligence to comb through online comments to detect threats not only on social media platforms such as X but also on the dark web, Komendat said. They look for what’s being said about the company, its employees and its leadership to uncover risks. “There are always threats directed towards senior leaders at companies. Many of them are not credible,” Komendat said. “The question always is trying to determine what is a real threat versus what is someone just venting with no intent to take any additional action.” Burton, a former special agent with the U.S. Diplomatic Security Service, points out that despite the current climate, there is little in the way of organized groups that target companies. Today, one of the primary worries are loners whose rantings online are fed by others who are like-minded. It’s up to corporate security analysts to zero in on such dialogue and decide whether or not it represents a real threat. And CEOs aren’t the only targets of disgruntled customers. In the U.S., there were 525 workplace fatalities due to assault in 2022, according to the National Safety Council. Industries including healthcare, education and service providers are more prone to violence than others, and taxi drivers are more than 20 times more likely to be murdered on the job than other workers, the group said. But the ambush of UnitedHealthcare’s Thompson this week is bound to get some CEOs second-guessing. “What invariably happens at moments like this in time is you will get additional ears listening” to security professionals seeking money to beef up executive protection, Burton said. “Because I can guarantee you there’s not a CEO in America who’s not aware of this incident.” Geller, Bussewitz and Liedtke write for the Associated Press.Report: Liverpool make €40m offer for Barca star with 35 goals & 48 assists; Arne Slot pushing for move
The Australian government's support for a UN resolution calling for an end to Israel's occupation of Gaza is to blame for a widely condemned arson attack on a Melbourne synagogue, the Jewish state's prime minister says. or signup to continue reading It is impossible to separate the reprehensible arson attack from the federal government's "extreme anti-Israeli position," Israeli Prime Minister Benjamin Netanyahu posted on social media early on Saturday. "Including the scandalous decision to support the UN resolution calling on Israel 'to bring an end to its unlawful presence in the Occupied Palestinian Territory, as rapidly as possible', and preventing a former Israeli minister from entering the country," he wrote on X. "The burning of the Adass Israel synagogue in Melbourne is an abhorrent act of antisemitism," he said. The Adass Israel synagogue at Rippon Lea in Melbourne's southeast had two of its three buildings gutted after suspected masked intruders allegedly broke into the building and set it alight in the early hours of Friday. Two congregants preparing for morning prayers, were inside. They were evacuated, with one sustaining minor injuries. Police have not ruled out terrorism as a motive, believing the attack was targeted. The suspects had poured accelerant on the floor inside the synagogue and set it on fire before fleeing when they were disturbed by a congregant, police said. Israel President Isaac Herzog said he firmly condemned the horrific arson amid an intolerable wave of attacks on Jewish communities when he spoke to Prime Minister Anthony Albanese on Friday night. "I noted to the prime minister that this rise and the increasingly serious antisemitic attacks on the Jewish community required firm and strong action, and that this was a message that must be heard clearly from Australia's leaders," he said. "I thanked him for his ongoing efforts to combat antisemitism, and expressed my trust that the local law enforcement would do everything in their power to bring the perpetrators to justice." Political and religious leaders have widely condemned the attack on the synagogue, built by Holocaust survivors. Mr Albanese said he had no tolerance for antisemitism. "This deliberate, unlawful attack goes against everything we are as Australians and everything we have worked so hard to build as a nation," he said in a statement. Australian Federal Police will provide all requested resources to Victorian authorities, he said. Victorian Premier Jacinta Allan said police patrols would be increased, and pledged $100,000 to rebuilding the synagogue. Advertisement Sign up for our newsletter to stay up to date. We care about the protection of your data. Read our . Advertisement
Sheltered Venezuelan government opponents decry police and intelligence agents outside embassyNone