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November 26, 2024 This article has been reviewed according to Science X's editorial process and policies . Editors have highlightedthe following attributes while ensuring the content's credibility: fact-checked peer-reviewed publication trusted source proofread by Chalmers University of Technology In addition to the urgent need for new antibiotics, alternative strategies are required to tackle the problem of antibiotic resistance. Michaela Wenzel, Associate Professor at Chalmers University of Technology, is investigating bacterial defenses against external stress to make these a target for efficient antibiotic treatments. When addressing the problem of antibiotic resistance , Michaela Wenzel highlights that globally, many lives could be saved with measures already practiced in Sweden. These include access to clean water, improved hygiene, and restrictions on antibiotic use in agriculture—but this alone is not enough. "We cannot stop bacteria from developing antibiotic resistance. It is evolution, and we will have to live with it. Of course, we need to find new substances that can act as antibiotics, but it is time-consuming and expensive. Therefore, we also need alternative strategies," she says. Wenzel is a microbiologist working at the Department of Life Sciences with a focus on bacterial cell biology. Her specific research interest is the molecular interaction between antibiotics and bacterial cells —examining what happens when antibiotics affect cells and how bacteria defend themselves. The cell envelope is an ideal target for treatments The bacteria's primary defense against their environment is an intact cell envelope, and changes to the envelope can be crucial for the cell's survival. This makes the cell envelope an ideal target for future treatments of bacterial infections. "Various types of ß-lactam antibiotics such as penicillin, which kill bacteria by targeting the synthesis of the cell wall, are among the most common treatments today. However, as resistance is rising, we need new ways to target the vital cell envelope," Wenzel explains. To understand how antibiotics affect different components of the cell envelope or how bacteria respond to antibiotics, her group uses and develops advanced microscopy techniques combined with spectroscopy and various omics technologies (large-scale analysis of genes, proteins, or other selected molecules in cells). "The cell envelope is both very well-studied and at the same time horribly understudied. There are certain things that we just cannot measure in living bacterial cells and artificial models will never truly capture the complexity of the living system. We are trying to develop and adapt methods to study these cell envelope parameters in living bacterial cells in real time and super resolution." Finding molecules that alter membrane channels The research team runs several parallel projects investigating protective stress mechanisms found in all bacteria, unrelated to evolutionary development of resistance, aiming to identify ways to disable them. One focus is on membrane channels in the cell envelope that transport molecules out of the cell. These channels' natural function is to release molecules from the cell upon hypoosmotic stress (adjustment to low-salt environments). Antibiotics targeting the cell envelope trigger the same response. Blocking the channel makes the bacteria more sensitive to antibiotics. At the same time, specific classes of antibiotics can hijack the channels when they are open and use them to enter the cells. Substances that act as either inhibitors or activators of these channels could therefore be useful, depending on the antibiotic used. "We aim to find molecules that can alter channel function, either to inhibit or activate the channel. The strategy is to use these molecules alongside different groups of existing antibiotics to maximize their effect. This approach will act as a combination therapy where the choice of antibiotic determines whether we activate or block the channel," says Wenzel. Collaborative project focused on dormant bacteria The research team is also part of a collaborative project focused on so-called non-growing cells. Some bacteria can enter a dormant state under unfavorable conditions, shutting down their metabolism. In this state, the cells are resistant to antibiotics and difficult to treat, often causing latent and recurring infections such as tuberculosis. The team has published a paper on this topic in Nature Communications . To kill non-growing cells, antibiotics must target cellular structures that are essential for survival, rather than metabolic processes. It is already known that several common antibiotics that block bacterial DNA or protein synthesis also increase the production of reactive oxygen species. These toxic radicals enhance the effect of the antibiotics. "In the study, we examined how antibiotics that affect the membrane of dormant bacteria kill the cells. We discovered a new mechanism where disruption of bacterial respiration leads to increased production of a reactive oxygen species, superoxide, which in turn causes cell death," says Wenzel. New approaches to fight fungal infections Collaborations in research projects are particularly important to her. It contributes not only to her development as a scientist but also to advancing research and strategies against antibiotic resistance through interdisciplinary efforts. In November 2024, a consortium including Wenzel's group received a grant, addressing the increasing problem with resistance to antifungal drugs and calling for new approaches to combat fungal infections. "The grant supports an interdisciplinary and international consortium aiming to develop metal compounds to combat various fungal infections. This is the first time my research group is specifically focusing on fungi, so we have a very exciting time ahead of us." More information: Declan A. Gray et al, Membrane depolarization kills dormant Bacillus subtilis cells by generating a lethal dose of ROS, Nature Communications (2024). DOI: 10.1038/s41467-024-51347-0 Journal information: Nature Communications Provided by Chalmers University of Technology
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Biden Administration to Loan $6.6B to EV Maker Rivian to Build Georgia FactoryATLANTA — On Jan. 18 and 19 the AT&T Playoff Playlist Live! will be held at State Farm Arena in advance of the College Football Playoff national championship on Jan. 20. The star-studded lineup was announced Thursday at a news conference at Mercedes-Benz Stadium. Performances will include Lil Wayne and GloRilla on Saturday; and Camila Cabello, Myles Smith and Knox on Sunday. On game day, the Allstate Championship Tailgate, taking place just outside Mercedes-Benz Stadium in the Home Depot Backyard, will feature country acts on the Capital One Music Stage, including global superstar Kane Brown and iHeartCountry “On The Verge” artist Ashley Cooke. The concerts are just two of the festivities visiting fans can enjoy in the days leading up to the big game. The fan experience for both ticket holders and the general public has been a focus for event planners. All weekend long, an estimated 100,000 people from across the country are expected to attend fan events preceding kickoff. People are also reading... “It will be an opportunity for fans of all ages to come together to sample what college football is all about, and you don’t have to have a ticket to the game to be a part of it,” said Bill Hancock, executive director of the CFP in a press release. “We’ve worked closely with the Atlanta Football Host Committee to develop fan-friendly events that thousands will enjoy come January.” On Saturday, Jan. 18, Playoff Fan Central will open at the Georgia World Congress Center in downtown Atlanta. The free, family-friendly experience will include games, clinics, pep rallies, special guest appearances, autograph signings and exhibits celebrating college football and its history. That day, fans can also attend Media Day, presented by Great Clips, which will feature one-hour sessions with student-athletes and coaches from each of the College Football Playoff national championship participating teams. ESPN and social media giants X, Facebook, Instagram and TikTok will be taping live broadcasts from the event. On Sunday, Jan. 19, the Trophy Trot, both a 5K and 10K race, will wind its way through the streets of downtown Atlanta. Each Trophy Trot participant will receive a T-shirt and finisher’s medal. Participants can register at atlantatrackclub.org . On Sunday evening, the Georgia Aquarium will host the Taste of the Championship dining event, which offers attendees the opportunity to indulge in food and drink prepared by local Atlanta chefs. This premium experience serves as an elevated exploration of local cuisine on the eve of the national championship. Tickets to the Taste of the Championship event are available on etix.com . Atlanta is the first city ever to repeat as host for the CFP national championship. The playoff was previously held in Atlanta in 2018. “We are honored to be the first city to repeat as host for the CFP national championship and look forward to welcoming college football fans from around the country in January,” said Dan Corso, president of the Atlanta Sports Council and Atlanta Football Host Committee. “This event gives us another opportunity to showcase our incredible city.” The College Football Playoff is the event that crowns the national champion in college football. The quarterfinals and semifinals rotate annually among six bowl games — the Goodyear Cotton Bowl Classic, Vrbo Fiesta Bowl, Capital One Orange Bowl, Chick-fil-A Peach Bowl, Rose Bowl Game presented by Prudential and the Allstate Sugar Bowl. This year’s quarterfinals will take place on Dec. 31, 2024 and Jan. 1, 2025, while the semifinals will be Jan. 9-10, 2025. The CFP national championship will be Monday, Jan. 20, 2025, at Mercedes-Benz Stadium. For additional information on the College Football Playoff, visit CollegeFootballPlayoff.com . Be the first to know Get local news delivered to your inbox!
The BMW 3 Series has always held a special place in the compact luxury sedan segment. Their refined style, performance, and comfort have become a benchmark. However, even the best cars may not meet everyone's needs. Some people are looking for more affordable options, unique styling, or innovative technology. Fortunately, the market offers many alternatives that can compete with the legendary "three." Cadillac CT4: affordability and style The Cadillac CT4 offers one of the best value options in the luxury sedan segment. With a base price of $34,995, the model is significantly cheaper than the BMW, and the CT4-V with a 325-horsepower engine makes it even more attractive. At the same time, the interior needs to be updated, but if you are interested in a balance of price and power, the CT4 is worth considering. Lexus IS: reliability and design The Lexus IS stands out for its stylish looks and traditional reliability. For $40,000, you get an atmospheric V6 that delivers plenty of power, though the transmission and interior may feel dated. This is the choice for those looking for durability in a classic design. Genesis G70: high performance The Genesis G70 starts at $42,000 and offers excellent equipment, including a 300-horsepower engine, Brembo brakes, and adaptive suspension. And the 365-horsepower version, priced lower than a BMW M340i, makes it one of the most attractive options for those who like to drive dynamically. Tesla Model 3: the electric car of the future The Tesla Model 3, with a starting price of $42,490, attracts with a range of up to 363 miles and 510 horsepower in the Performance version. Its minimalist design and modern technology make it an ideal choice for those looking for an electrified alternative. Volvo S60: Scandinavian elegance The Volvo S60, priced at $43,795, is suitable for those who value comfort and restraint. Its hybrid version strikes a balance between environmental friendliness and performance, while its classic design adds to the car's uniqueness. Alfa Romeo Giulia: Italian passion The Alfa Romeo Giulia combines stylish design with pleasant handling. With a price starting at $43,995 and a 280 horsepower engine, this car remains competitive despite the lack of the legendary V6. Audi A4: the German alternative The Audi A4 ($44,100) offers a refined interior and ample performance with a 261-horsepower engine. Although it will be replaced by the new A5 model, the A4 remains a great choice for those who appreciate German quality. Mercedes-Benz C-Class: the ultimate in luxury Starting at $48,450, the Mercedes-Benz C-Class impresses with its luxurious interior, technology, and sophisticated style. It is an ideal choice for those who put comfort and premium above all else. Subscribe to the OBOZ.UA channels on Telegram and Viber to keep up with the latest events.
Some Black Friday deals are still available, and the deals on different smart devices are some of the best we've ever seen as Cyber Monday approaches. Robot vacuums are just one category, with major pricing discounts during the year's biggest shopping event. ZDNET is gathering the best and most legitimate deals available right now, so you won't have to worry about wading through the madness of deal hunting. Also: The best Black Friday deals: Live updates As a robot vacuum reviewer and dog owner, I'm always looking for great deals on how to keep my home clean with as little effort as possible. I test different types of robot vacuums daily and have grown exceedingly familiar with each brand's strengths and weaknesses and their price fluctuations. As a result, I've realized that this is the best time to buy that robot vacuum you've had your eye on all year or as a holiday gift for that family member who's always wanted one. Read on to find the best deals on robot vacuums and cordless vacuums that are still available after Black Friday through Cyber Monday. Our favorite robot vacuum deals for Black Friday 2024 iRobot Roomba s9+ and Braava Jet m6 bundle : $420 (save $1,029 at Best Buy): This is, by far, the best deal you can get on a robot vacuum and mop bundle, as it went on clearance just in time for Black Friday. Narwal Freo X Ultra robot vacuum and mop : $800 (save $300 at Best Buy): The highly rated Narwal Freo X Ultra is a top-performing robot vacuum and mop with 8,200Pa of suction power. Roborock Q8 Max+ robot vacuum and mop : $420 (save $400 at Amazon): In addition to a Q8 robot vacuum and mop, the Max model includes a self-emptying dock that you don't have to worry about for up to seven weeks. Dreame X40 Ultra robot vacuum and mop : $1,000 (save $900 at Amazon): This is my favorite robot vacuum and mop combination that I've tested, with excellent obstacle avoidance and strong suction. Dreame X30 Ultra robot vacuum and mop : $800 (save $600 at Amazon): This is the lowest price on the Dreame X30 Ultra, which was ZDNET's top pick for the best 2-in-1 robot vacuum and mop , dethroned only by its successor, the X40 Ultra . Yeedi M12 Pro+ robot vacuum and mop : $550 (save $449 at Amazon): Have you ever heard the phrase "high-end features for a mid-range price?" This hands-free robot vacuum and mop does all the work for you, with flagship features like an extending mop pad to reach corners and under cabinets and 11,000Pa of suction. Airrobo T20+ robot vacuum and mop : $280 (save $220 at Amazon): This is one of the lowest prices we've ever seen on this Airrobo self-emptying robot vacuum and mop. Ecovacs Deebot X2 Combo complete robot vacuum and mop : $1,414 (save $286 at Amazon): I rely on the Deebot X2 Combo Complete robot vacuum and mop , especially because of its side-mounted cordless vacuum that empties automatically. Roborock S8 Pro Ultra robot vacuum and mop : $900 (save $700 at Amazon): The all-in-one S8 Pro Ultra features 6,000Pa of suction power, a self-emptying dustbin, and self-washing mop pads. Eufy X8 Pro Current price: $350 Original price: $650 The Eufy X8 Pro twin-turbine robot vacuum is perfect for pet owners. With 4,000Pa of suction power, this robot vacuum includes a self-empty station and smooth navigation to leave beautiful carpet lines behind. Review: Eufy X8 Pro: A must-have for homes with a lot of carpet iRobot Roomba Combo j9+ Current price: $975 Original price: $1,399 The flagship Roomba j9+ features powerful suction and a self-emptying dustbin, perfect for pet owners. This combo option also has a retractable mop pad that stores itself on top of the robot when not in use, ensuring your carpets stay dry and your hard floors stay mopped. Also: How Roomba's $1,000 robot vacuum handled my house of children and pets Ecovacs Deebot T30S Combo Current price: $800 Original price: $1,200 The Deebot T30S combo is fairly new but lives up to the hype that only a three-in-one robot vacuum could garner. This has become my go-to upstairs robot vacuum and mop because it functions as a cleaning hub, made complete by the self-emptying cordless vacuum that charges right on the robot's charging station. Review: I tested a robot vacuum with a handheld vacuum that empties itself Roborock Q8 Max+ Current price: $420 Original price: $820 For a limited time, you can snag the Roborock Q8 Max+ for $420. As a vacuum mop combo, this machine features 4,200Pa suction power and 300g mopping pressures, promising a smooth and efficient clean. With its self-empty dock, you can have hands-free vacuuming for up to seven weeks. Thanks to Roborock's PreciSense LiDAR Navigation, you can rest assured that this robot vacuum will clean where it's supposed to and when it's supposed to. Also: The best robot vacuum mops you can buy iRobot Roomba Combo j5 Current price: $285 Original price: $530 If you're like me and love the idea of your floors being cleaned by someone or something else, you can't go wrong with this deal. The Roomba j5 is a robot vacuum that intelligently maps and navigates your home, avoiding obstacles like cords and pet waste. Also: Roomba Combo J7+ review: A 2-in-1 robot vacuum done (almost) right Best Black Friday iRobot robot vacuum deals iRobot Roomba j7+ robot vacuum : $359 (save $441 at Amazon): This discount on a self-emptying Roomba powered by RobotOS is a deal you can't miss. iRobot Roomba s9+ and Braava Jet m6 bundle : $420 (save $1,029 at Best Buy): This is, by far, the best deal you can get on a robot vacuum and mop bundle, as it went on clearance just in time for Black Friday. iRobot Roomba® Vac 2 Essential robot vacuum : $250 (save $150 at Amazon): This is an introductory offer on iRobot's brand new entry-level robot vacuum, featuring the AutoEmpty dock, for self-emptying. iRobot Roomba Combo j5 robot vacuum and mop : $285 (save $245 at Amazon): The Roomba Combo j5 is built for everyday vacuuming with occasional mopping. iRobot Roomba Combo i5+ Self-Emptying Robot Vacuum & Mop : $300 (save $250 at Target): Whether your mess is wet or dry, the Roomba ComboTM i5+ robot vacuum and mop can handle it. iRobot Roomba Combo j9+ robot vacuum and mop : $975 (save $424): The flagship Roomba j9+ features powerful suction and a self-emptying dustbin, perfect for pet owners . iRobot Roomba Essential Combo robot vacuum and mop : $226 (save $47 at Amazon): This essential robot vacuum is an entry-level Roomba that combines powerful suction with mopping action. iRobot Roomba Combo Essential Robot : $160 (save $115 at Target): If you're looking for a basic combination robot vacuum and mop, this Roomba Combo deal is hard to beat. Best Black Friday Roborock robot vacuum deals Roborock S8 Pro Ultra robot vacuum and mop : $900 (save $700 at Amazon): The all-in-one S8 Pro Ultra features 6,000Pa of suction power, a self-emptying dustbin, and self-washing mop pads. Roborock Q7 Max robot vacuum and mop : $200 (save $100): At 33% off, this Roborock discount won't last long. Roborock S8+ robot vacuum and mop : $550 (save $450 at Amazon): The Roborock S8+ features 6,000Pa of suction power, a self-emptying dustbin, and the company's Sonic Mop system. Roborock Flexi Lite wet/dry vacuum and mop : $180 (save $220 at Amazon): This outstanding wet/dry vacuum and mop lets you tackle wet and dry messes in one fell swoop. Best Black Friday Shark robot vacuum deals Shark AV2501S AI Ultra robot vacuum : $329 (save $221 at Amazon): This bagless, self-emptying vacuum cleaner can hold up to 30 days' worth of debris and pet hair. Shark PowerDetect NeverTouch Pro robot vacuum and mop : $700 (save $500 at Amazon): This is Shark's flagship robot vacuum and mop, with a water tank that lasts up to 30 days without refilling and up to 60 days self-emptying bagless capacity. Shark PowerDetect NeverTouch robot vacuum and mop : $550 (save $350 at Amazon): This robot vacuum's bagless design ensures you don't have to buy new dustbags to replace and can dump the contents in the trash. Shark AV2610WA robot vacuum and mop : $484 (save $216 at Amazon): You can forget about handling dust yourself, as this Shark can hold up to two months' worth of debris. Best Black Friday Eufy robot vacuum deals Eufy 11S Max robot vacuum : $130 (save $120 at Amazon): This is my pick for the best budget-friendly robot vacuum for pet hair right now. It has strong suction and carpet boost technology. Eufy X8 Pro robot vacuum : $350 (save $300 at Amazon): The Eufy X8 Pro twin-turbine robot vacuum is perfect for pet owners , especially those with mostly carpets. Eufy G30 robot vacuum : $140 (save $179 at Amazon): For $140, you can buy a robot vacuum with reliable navigation, checking one more task off your cleaning to-do list for its lowest price ever. Eufy L60 robot vacuum : $280 (save $120 at Amazon): This highly rated Eufy robot vacuum has a self-emptying station that holds up to 60 days' worth of dust and debris. Eufy RoboVac 15C MAX robot vacuum : $120 (save $160 at Amazon): This entry-level robot vacuum is great for hard floors, apartments, and small areas, and it's currently 57% off. Best Black Friday cordless vacuum deals Tineco Pure One Station cordless vacuum : $339 (save $120 at Amazon): This is the most powerful stick vacuum I've ever tested; the self-emptying dock takes it to the next level, so it quickly became my go-to. Narwal S20+ vacuum/mop : $400 (save $100 at Best Buy): This wet/dry vacuum and mop uses advanced AI-powered sensors to detect dirt and boost performance. Eureka RapidClean Pro stick vacuum : $105 (save $45 at Amazon): This cordless vacuum comes with two attachments to clean everything from floors to upholstery and narrow crevices. Levoit LVAC-200 stick vacuum : $150 (save $50 at Amazon): Get a lightweight cordless vacuum for only $150 through Black Friday. Bissell CleanView XR 200W stick vacuum : $114 (save $85 at Amazon): This is a huge discount on a stick vacuum with a removable battery and XL dustbin. Shark Pet stick vacuum : $150 (save $110 at Amazon): The unbeatable 43% discount on a Shark cordless vacuum gets you powerful suction and up to 40 minutes of runtime. Eureka Stylus Elite stick vacuum : $193 (save $96 at Amazon): In addition to an $86 discount, you can take an extra $20 off to get a powerful cordless vacuum and self-emptying station. Dyson V8 Plus stick vacuum : $420 (save $50 at Amazon): You can't go wrong with a Dyson cordless vacuum, especially at 36% off. Roborock Flexi Lite wet/dry vacuum and mop : $180 (save $220 at Amazon): This outstanding wet/dry vacuum and mop lets you tackle wet and dry messes in one fell swoop. FAQs Black Friday is a big shopping event that occurs each year on the day after Thanksgiving. This year, it happened on Nov. 29. Since Thanksgiving is always on a Thursday, many people are off through the weekend, so retailers have capitalized on this day, the last national holiday before Christmas. This makes Black Friday a great chance to finish checking off your holiday shopping list. Cyber Monday happens on the Monday following the Thanksgiving holiday. This year, Cyber Monday falls on Dec. 2. Robot vacuums are cheaper during big shopping events like Black Friday, Cyber Monday, and Amazon Prime Day. The fact that Black Friday is one of the last major shopping events of the year results in some retailers giving big discounts on the current product stock in preparation for new devices launching in the new year. Though there are many online deals, Black Friday has been historically a mostly in-person shopping event where people visit a brick-and-mortar store. With most big box stores featuring an online store, Black Friday online shopping has become as common as Amazon Prime Day shopping. Cyber Monday began and remains an online shopping event for online stores to capitalize on customers who may have missed a Black Friday deal and can shop from home or work on Monday. As a robot vacuum tester at ZDNET, I've become familiar with these devices' unique features and tested different models in every price range. This experience has made me realize that the robot vacuum market is saturated with competition. It also helps me discern which robot vacuums are worth their retail price and when a discount is a good deal. I check robot vacuum deals often, always choosing the ones that deliver the most features for the least money. Using our expertise and different tools to track deals, we can determine when a deal is worth it and ensure we only cover those. This list of deals will be updated as new deals appear and others sell out. While retailers hold store-specific shopping events throughout the year, like Amazon with Prime Day, you can expect Black Friday and Cyber Monday deals to appear everywhere. This includes your local businesses and big box stores. Black Friday is a huge shopping event, both in-person and online, with stores like Walmart, Best Buy, Amazon, Target, Costco, and more offering eye-popping discounts on different products. ZDNET's experts have searched through Black Friday sales live for the best discounts by category. These are the best Black Friday deals so far by category: Black Friday TV deals Black Friday phone deals Black Friday laptop deals Black Friday gaming PC deals Black Friday smartwatch and fitness tracker deals Black Friday Amazon deals Black Friday Best Buy deals Black Friday Walmart deals Black Friday Sam's Club deals Black Friday Apple deals Black Friday iPad deals Black Friday AirPods deals Black Friday Apple Watch deals Black Friday Kindle deals Black Friday streaming deals Black Friday soundbar and speaker deals Black Friday robot vacuum deals Black Friday Nintendo Switch deals Black Friday PlayStation deals And more Black Friday deals: Black Friday deals under $25 Black Friday deals under $100 Black Friday Samsung deals Black Friday Verizon deals Black Friday headphone deals Black Friday tablet deals Black Friday monitor deals Black Friday gaming deals Black Friday security camera deals Black Friday storage and SSD deals Black Friday portable power station deals Black Friday VPN deals Black Friday Chromebook deals Black Friday HP deals Black Friday Dell deals Black Friday Roku deals Black Friday Roborock deals Best Black Friday deals Black Friday phone deals Black Friday TV deals Black Friday laptop deals
Horoscope Today, 1 December 2024, Rashifal, Lucky Colour, Auspicious Time for Zodiac SignsAshley Ridge, Fort Dorchester and Summerville entered this wrestling season ranked in the Top 10 for their division. The South Carolina Wrestling Coaches Association released its 2024 preseason rankings earlier this month and some local teams have already begun their 2024-25 season. Summerville is the top-ranked 5A, Division 1 team in the state after finishing last season as the state runner-up behind Fort Mill. Trailing in the Top 10 for the division, from second to 10th, are Carolina Forest, James Island, Fort Dorchester, Boiling Springs, River Bluff, Stratford, Byrnes, Ashley Ridge and Rock Hill. Cane Bay is ranked 15th while West Ashley is ranked 17th and Wando 18th. “We have a very strong group this year,” Summerville coach Daryl Tucker said. “I like our lineup if we can just stay healthy.” The Green Wave has three past state qualifiers leading the way this season. Junior Kayleb Pinckney lost to Nation Ford’s Danny Gilstorf in the 132-pound weight class during the semifinals of the 2024 state individual championships. Senior Landon Deaton was a 2023 state qualifier at 106. Senior Caleb Herring placed second in 2023 for the 126-pound class. Last season, Fort Mill handed Summerville a 32-27 loss during the Class 5A team championship. The Yellow Jackets were ranked third in the class entering the playoffs while the Green Wave was ranked first, as it had been for much of the season. The Green Wave finished the season with a 27-3 record and as a region champion and Lower State Champion for the third time in the past four seasons. Ashley Ridge and Fort Dorchester placed second and third, respectively, in their region behind Summerville last season. Ashley Ridge was eliminated from the playoffs in the second round by Goose Creek and Fort Dorchester fell in the same round with a loss to River Bluff. This season, the Patriots are led by four returning state qualifiers. Sophomore Richard Springs won the 120 class in 2024, claiming an 8-3 decision over Byrnes’ Hampton Higdon in the championship match. He also won a state title at 113 in 2023 and a state-title at 106 in 2022. Sophomore Evan Gates went 2-1 at 106 during last year’s championships to finish as the state runner-up. Senior Zach Gomer-Chrobocinski lost to Dutch Fork’s Jackson Stocker in the 113-pound semi-finals to finish in third place. In 2023 he placed third at 106. Fellow Fort senior Caleb Wilson qualified at 126 in 2024 and at 120 in 2023. Ashley Ridge has one returning state qualifier, senior Jeremiah Venning. He wrestled at 190 last season. Eastside is the top ranked team for 5A, Division 2. Rounding out the Top 10 for that division are Indian Land, Lugoff-Elgin, Chapin, Fort Mill, Greenwood, Goose Creek, Woodmont, Hillcrest and TL Hanna. Berkeley is ranked 20th in the division, but has four returning state qualifiers. Full wrestle rankings can be found at scmat.com , which compiles the rankings for the association. The next team and individual rankings are scheduled to be released Dec. 19.
Every Black Friday, there’s a number of viral products that everyone has on their Christmas wish list, and we don’t expect this year to be any different. However, not all of these popular items are going to stay in stock, and we have some insight on the ones that won’t. Black Friday is big business, and last year shoppers spent $222.1 billion during the entire holiday shopping season, according to Queue-it. Sales on Black Friday reached $16.4 billion (online and in stores), and this was a 9% increase from the year before. While it comes as no surprise that electronics are the most sought-after products of the holiday season, Queue-it said this accounts for the majority of holiday sales, jumping to $50.8 billion in 2023. Apparel, furniture, groceries and toys are the other hot sellers of Black Friday. Together, these five categories accounted for 65% of sales during the holidays last year and is only expected to grow in 2024. While many items that sell out over Black Friday are driven by a good deal, we also know that a hot product is just that — a gift that most people want to open on Christmas Day. So, here are our picks for the top 10 hot-ticket items that could sell out over Black Friday. Samsung 98-inch QLED TV The holidays are ripe for TV deals, and we expect shoppers to buy a ton of them in 2024, especially at Walmart. Consumers are trending toward bigger TVs and the super low-price deals over Black Friday force many models to sell out. This is especially true of popular models from Samsung, Hisense, LG and more favorites. Apple Watch Series 9 Apple's smartwatches are a top pick among Apple fans. We’ve seen prices on the Apple Watch continue to trend downward, which was only spurred by the release of the new Apple Watch 10 in September. This pushed down prices on earlier models, with the best deals coming on the Apple Watch SE and Apple Watch 9. For Black Friday, we think the prices will drop even lower and sell out due to high demand. Beats Solo3 Wireless headphones are one of the most popular products of 2024, and Beats are one of the top brands. We’re already seeing big markdowns on Beats Wireless Headphones, and we expect these price drops to continue into Black Friday. The Beats Solo3 is likely to be on sale for even cheaper than we’ve already seen, and we think they will sell out for Black Friday, with the possibility of other popular Beats headphones joining them. Apple AirPods (3rd gen) If you haven’t picked up a pair of Apple AirPods yet, this could be your year to do it. With Apple launching a fourth generation of AirPods earlier this year, the price on prevvious models are creeping lower. We think over Black Friday they’ll be at their cheapest price ever, with the AirPods (3rd Gen) likely to sell out. JBL Flip 6 Bluetooth speakers are a must-have for many this year, and with the big sound that comes from JBL’s speakers, it’s easy to see why they might sell out for Black Friday. These popular speakers come in a variety of portable sizes and waterproof designs. We expect big deals on JBL’s top-rated Clip 5 and Flip 6 Bluetooth speaker models. Apple iPad (10th Gen) One of Apple’s most sought-after products of the year was the iPad, and we saw the 9th Gen and 10th Gen models drop to their lowest prices ever. We think this year will bring some iPad bliss with even better discounts, but these deals will disappear just as fast as they arrive. We think that mega discounts on the iPad (9th Gen) and iPad (10th Gen) could cause sell outs, especially on Amazon. Dyson Airwrap The Dyson Airwrap just might be the top product of Black Friday, as this is one of the rare times there’s a discount on the beloved hair styling tool. At $600, the Airwrap carries a hefty price tag, so any discount presented is a welcome surprise. But as we’ve seen in the past, any Black Friday deal on the Dyson Airwrap causes a crush of interest that’s followed by a sell out. Ugg Tasman slippers If you’ve tried to scoop up the UGG Tasman Slippers in previous years, you already know they never stay in stock for long. As the “it” slipper of the holiday season, UGG’s Tasman sells out multiple times over the holidays, even without a discount offered. We think that this year will be similar, with popular sizes and colors of the Tasman Slipper snatched up fast over Black Friday. Bissell Little Green The Bissell Little Green carpet cleaner is a popular home product that just can’t seem to stay in stock. With prices falling under $90, this mighty machine can be a blessing for pet owners and parents, as its compact size makes it easy to store and use when needed. We’ve seen the Little Green Machine sell out before, and we’d be surprised if it didn’t do it again over Black Friday. Furby Galaxy Edition We’d be remiss if we didn’t include a top toy that we think will be hard to find and gift this year. Our pick is the Furby Galaxy Edition. This glow-in-the-dark Furby is based on the original Furby from the late ’90s with even more features, interactive modes and more fun. Making a comeback in 2023, we saw the revival of this popular toy sell out last year, and we expect the new Furby Galaxy Edition to do the same. Get the latest local business news delivered FREE to your inbox weekly.Cemtrex Announces 1-For-35 Reverse Stock SplitDENVER (AP) — Travis Hunter made a pair of proclamations Thursday: He’s for sure entering the NFL draft after this season, but not until he sees C olorado all the way through the College Football Playoff — if the Buffaloes make it there. The first was already a given for the draft-eligible junior who plays both receiver and cornerback. The second is a risk-reward play for a projected high first-round pick who averages around 120 snaps a game. In years past, it took two extra postseason wins to capture a national title. Now, it could take up to four additional contests. That’s more of a chance to shine, but also more chance for an injury. “I don’t think nobody will opt out because you’re showing NFL teams that you’re more focused on something else, other than the team goal,” Hunter said of the expanded 12-team College Football Playoff. “So I don’t think players are going to opt out of the playoffs.” Hunter and quarterback Shedeur Sanders chatted Thursday in a set of Zoom calls about turning around the program at Colorado (from 4-8 last season to bowl eligibility), chasing a Big 12 title, turning pro — Hunter acknowledged he will “for sure” — and, of course, the Heisman race, where Hunter is currently the odds- on favorite in an aw ard each wants to see the other win. “He’s deserving of it, and if it’s between me and him, I want him to get it,” said Sanders, whose 16th-ranked Buffaloes (8-2, 6-1 Big 12, No. 16 CF P) travel to Arrowhead Stadium to face Kans as (4-6, 3- 4) this weekend. “He does a lot of amazing things that have never been done before.” Countered Hunter: “I know he wants me to win it, but I also want him to win as bad as I want to win it.” Hunter is a generational talent shining on both sides of the ball. As a receiver, he has 74 catches for 911 yards and nine touchdowns. On defense, he has picked off three passes, even though teams are reluctant to throw his direction. Like he did in high school and now in college, he believes he can do both on the next level. But he understands the trepidation of the NFL team that picks him. “They don’t want their top pick to go down too early,” Hunter said. “I like when people tell me I can’t do it, because they just motivate me to continue to do what I want to do.” Sanders is turning in a stellar season as well with 27 touchdown passes, one away from tying Sefo Liufau for the most in a single season in program history. He’s projected to be one of the first QBs off the draft board. The future certainly looks bright at Colorado thanks to the legacies Sanders and Hunter under coach Deion Sanders. But that’s a point to ponder later. “I can’t think too much forward past Saturday,” Shedeur Sanders cracked. “The main thing is winning the Big 12 championship. That’s the main thing we’re focused on.”
For most of the people of Lebanon, a ceasefire could not come quickly enough. A leading Lebanese analyst at a conference on the Middle East that I’m attending in Rome said she couldn’t sleep as the appointed hour for the ceasefire came closer. “It was like the night before Christmas when you’re a kid. I couldn’t wait for it to happen.” You can see why there’s relief. More than 3,500 citizens of Lebanon have been killed in Israeli strikes. Displaced people packed their cars before dawn to try to get back to whatever remains of their homes. Well over one million of them have been forced to flee by Israeli military action. Thousands have been wounded and the homes of tens of thousands of others have been destroyed. But in Israel, some feel they have lost the chance to do more damage to Hezbollah. Prime Minister Benjamin Netanyahu met the heads of Israel’s northern municipalities, which have been turned into ghost towns with around 60,000 civilians evacuated further south. Israel’s Ynet news website reported that it was an angry meeting that turned into a shouting match, with some of the local officials frustrated that Israel was taking the pressure off their enemies in Lebanon and not offering an immediate plan to get civilians home. In a newspaper column, the mayor of Kiryat Shmona, close to the border, said he doubted the ceasefire would be enforced, demanding that Israel creates a buffer zone in south Lebanon . In a poll commissioned by the Israeli station Channel 12 News those questioned were roughly split between supporters and opponents of the ceasefire. Half of the participants in the survey believe Hezbollah has not been defeated and 30% think the ceasefire will collapse. Back in late September, at the UN General Assembly in New York, a deal looked as if it was close. Diplomats from the US and UK were convinced that a ceasefire very similar to the one that is now coming into force was about to happen. All sides in the war appeared to have signalled their willingness to accept a ceasefire based on the provisions of Security Council resolution 1701, which was passed to end the 2006 Lebanon war: Hezbollah would pull back from the border to be replaced by UN peacekeepers and the Lebanese Armed Forces. As they moved in, Israeli forces would gradually move out. But prime minister Netanyahu went to the podium at the UN to deliver a fiery speech that refused to accept any pause in Israel’s offensive. Back at his New York hotel Netanyahu’s official photographer captured the moment as he ordered the assassination of Hassan Nasrallah, the leader of Hezbollah, along with most of his high command. Netanyahu’s office released the photos, in another calculated snub for American diplomacy. The assassination was a significant escalation and a blow to Hezbollah. In the weeks since, Israel’s military has inflicted immense damage to Hezbollah’s military organisation. It could still fire rockets over the border and its fighters continued to engage Israel’s invasion force. But Hezbollah is no longer the same threat to Israel. Military success is one of several factors that have come together to persuade Benjamin Netanyahu that this is a good time to stop. Israel’s agenda in Lebanon is more limited than in Gaza and the rest of the occupied Palestinian territories. It wants to push Hezbollah back from its northern border and to allow civilians to return to border towns. If Hezbollah looks to be preparing an attack, Israel has a side letter from the Americans agreeing that it can take military action. In a recorded statement announcing his decision, Netanyahu listed the reasons why it was time for a ceasefire. Israel, he said, had made the ground in Beirut shake. Now there was a chance ‘to give our forces a breather and replenish stocks,’ he continued. Israel had also broken the connection between Gaza and Lebanon. After the late Hassan Nasrallah ordered the attacks on Israel’s north, the day after Hamas went to war on 7th October last year, he said they would continue until there was a ceasefire in Gaza. Now, Netanyahu said, Hamas in Gaza would be under even more pressure. Palestinians fear another escalation in Israel’s Gaza offensive. There was one more reason; to concentrate on what Netanyahu called the Iranian threat. Damaging Hezbollah means damaging Iran. It was built up by the Iranians to create a threat right on Israel’s border. Hezbollah became the strongest part of Iran’s axis of resistance, the name it gave to its network of forward defence made up of allies and proxies. Just like Hezbollah’s surviving leaders, their patrons in Iran also wanted a ceasefire. Hezbollah needs a pause to lick its wounds. Iran needs to stop the geostrategic bleeding. Its axis of resistance is no longer a deterrent. Iran’s missile attack on Israel after Nasrallah’s assassination did not repair the damage. Two men, both now assassinated, designed Hezbollah to deter Israel not just from attacking Lebanon – but also from attacking Iran. They were Qasem Soleimani, head of the Quds Force of Iran’s Revolutionary Guards, who was killed by an American drone strike at Baghdad airport in January 2020. The order was issued by Donald Trump in his last few weeks in the White House at the end of his first term. The other was Hassan Nasrallah, killed by a huge Israeli air strike in Beirut’s southern suburbs. Hezbollah and Iran’s deterrence strategy matched Israel’s own deterrence for almost 20 years after the end of the 2006 war. But among the profound changes caused by the 7th October attacks was Israel’s determination not to accept restrictions on the wars it would wage in response. America, its most important ally, also put almost no restrictions on the supply or use of the weapons it kept on providing. Nasrallah and Iran failed to see what had happened. They did not understand how Israel had changed. They sought to impose a war of attrition on Israel, and succeeded for almost a year. Then on 17th September Israel broke out of it by triggering the miniature bombs built into the network of booby-trapped pagers its intelligence services had duped Hezbollah into buying. Hezbollah was thrown off balance. Before it could react with the most powerful weapons Iran had provided, Israel killed Nasrallah and most of his key lieutenants, accompanied by massive strikes that destroyed arms dumps. That was followed by an invasion of South Lebanon and the wholesale destruction of Lebanese border villages as well as Hezbollah’s tunnel network. A ceasefire in Lebanon is not necessarily a precursor to one in Gaza. Gaza is different. The war there is about more than security of the border, and Israeli hostages. It is also about revenge, about Benjamin Netanyahu’s political survival, and his government’s absolute rejection of Palestinian aspirations for independence. The Lebanon ceasefire is fragile and deliberately paced to buy time for it to work. When the 60 days in which it is supposed to take effect ends, Donald Trump will be back in the Oval Office. President-elect Trump has indicated that he wants a ceasefire in Lebanon, but his precise plans have not yet emerged. The Middle East is waiting for the ways he might affect the region. Some optimists hope that he might want to create a moment akin to President Nixon’s sensational visit to China in 1972 by reaching out to Iran. The pessimists fear he might abandon even the hollow genuflection that the US still makes to the idea of a creating an independent Palestine alongside Israel – the so-called two state solution. That might pave the way to annexation of those parts of the occupied Palestinian territories Israel wants, including much of the West Bank and northern Gaza. What is certain though is that the Middle East has no chance of escaping more generations of war and violent death until the region’s fundamental political ruptures are faced and fixed. The biggest is the conflict between Israel and the Palestinians. Benjamin Netanyahu and his government, along with most Israelis believe it is possible to dominate their enemies by pressing on to a military victory. Netanyahu is actively using force, unrestrained by the US, to alter the balance of power in the Middle East in Israel’s favour. In a conflict that has lasted more than a century both Arabs and Jews have dreamt repeatedly of peace through military victory. Every generation has tried and failed. The catastrophic consequences of the Hamas attacks on Israel on 7 October 2023 ripped away any pretence that the conflict could be managed while Israel continued to deny Palestinian rights to self-determination. The ceasefire in Lebanon is a respite. It is not a solution. Top picture credit: Getty Images BBC InDepth is the new home on the website and app for the best analysis and expertise from our top journalists. Under a distinctive new brand, we’ll bring you fresh perspectives that challenge assumptions, and deep reporting on the biggest issues to help you make sense of a complex world. And we’ll be showcasing thought-provoking content from across BBC Sounds and iPlayer too. We’re starting small but thinking big, and we want to know what you think - you can send us your feedback by clicking on the button below.
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