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New York state government to monitor its use of AI under a new lawThe former Geordie Shore star, who is nearly eight months pregnant, thanked a security company “for all the hard work this week” after adding the protections to her home. “Trebling our security measures, worth every penny to feel safe again in my own home,” the 34-year-old said in a post to her Instagram story. “Scumbags are gunna get a big shock the next time they even step foot on any perimeter of my land.” It comes after her fiance, Jake Ankers, said on social media that a group of men carrying a machete entered their home on Thursday evening while they were in the house with their two-year-old daughter. The businessman said one of the four men “had a red balaclava on” and was carrying the weapon at the top of the stairs. Durham Constabulary were alerted at 7pm on Thursday to reports of an aggravated burglary in Houghton-le-Spring, a town in the Sunderland area. A spokeswoman for the force said: “Officers attended the area, however the suspects left the scene before their arrival. “Nobody was injured in the incident and no items are believed to have been taken.” She added that an investigation is under way and anyone with information is asked to contact police. After the incident, Crosby was admitted to hospital after experiencing “serious pains” in her stomach, but confirmed her baby is “all fine”. Ankers appeared with the reality star on BBC Three reality show Charlotte In Sunderland. Crosby is best known for appearing in the MTV reality series Geordie Shore and winning the 12th series of Celebrity Big Brother in 2013. She and Ankers got engaged in October 2023 after she gave birth to their first child in 2022.
outboundIQ Achieves Certified Implementation Partner (CIP) Status with Five9
Early tallies in Ireland's General Election hint at challenges for incumbents and potential new alliancesVICTORIA — British Columbia Premier David Eby says 25-per-cent U.S. tariffs on Canadian goods would be "devastating" for the province's lumber and forestry industries. He made the comment ahead of a meeting with fellow first ministers and Prime Minister Justin Trudeau. Eby was scheduled to participate in the virtual meeting on Wednesday to discuss U.S. president-elect Donald Trump's threat to impose the tariffs unless Canada and Mexico stop illegal border crossings and prevent illicit drugs from entering the United States. Eby said the lumber and forestry sectors are already strained by a recent increase in duties amid the ongoing U.S.-Canada dispute over softwood lumber. He said after the first meeting of his new cabinet in Victoria that the tariffs are "unjustified," and they would hurt Americans as much as they would Canadians. The premier said B.C. is a source of natural gas, wood products, minerals and other products that U.S. businesses depend on, and the tariff would hinder jobs and opportunities in the province while making "life more expensive for Americans." Eby and Ottawa have called for a united front dealing with Trump's tariff plan, which he announced on social media on Monday. Eby said B.C. officials had repeatedly raised concerns with Ottawa over organized crime and illicit drugs, such as fentanyl, in relation to border security. "It's a priority for us. It has been for a while, we've written to Ottawa about it. Doesn't justify the tariffs, but it does mean that we can talk about those issues as well." Eby said Trump's proposed tariff "doesn't make economic sense," and the measure is not necessary to address issues at the border. The premier said he believes B.C. has a strong case to make for the tariff being "badly placed" if Trump's priority is to reduce costs for Americans. "I think the premiers are unified," Eby said. "There are 13 of us plus the prime minister. It's a big group of people with different political perspectives, but on this issue of ensuring that we're protecting the people in our country from these unjustified tariffs, I believe we're completely in line on that question." This report by The Canadian Press was first published Nov. 27, 2024. The Canadian Press
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Delivering Optimized, Outbound-Focused Contact Center Solutions for Modern Businesses LAUDERDALE LAKES, Fla. , Dec. 27, 2024 /PRNewswire/ -- outboundIQ www.outboundiq.com proudly announces its accreditation as a Five9 Certified Implementation Partner (CIP), a distinction that reflects its deep expertise in optimizing and streamlining outbound-focused contact center operations. With a team of seasoned Five9 veterans, expert programmers, and industry thought leaders, outboundIQ is uniquely equipped to help businesses of all sizes unlock the full potential of Five9's Virtual Contact Center platform. Optimized Solutions for Complex Contact Center Needs outboundIQ specializes in providing expedited, outbound-focused contact center implementations, integrating advanced features such as inbound and outbound Voice, SMS, Chat, Email, Salesforce Integration, and other third-party app integrations. Clients can also leverage ongoing optimization engagements and monthly retainers for strategic consulting designed to support long-term, outreach-focused success. "Who better to handle your domain configuration than the experts that understand the outbound contact center world. To be an outbound expert, you must know 3 things; how to configure the domain front end, how the architecture interprets that design, and how carriers respond to your dialing behavior as a result of the build. outboundIQ has the advantage of deeply understanding all 3 things. Our experts are seasoned professionals that will guide toward the best build for your business. You tell us about your business, your needs and your processes, and we will build you a domain fit for purpose. outboundIQ offers best in class Domain Optimization, Implementation and Consulting for customers of all sizes and complexity. Due to our methodology and proprietary automations, we are able to bring our customers' projects to life within accelerated timeframes." - Jessica Clay , VP Support and Services "We launched our business in June and were fortunate to connect with the incredible team at outboundIQ early on. Navigating the world of outbound calling and building efficient prospecting systems isn't easy, but the entire team at outboundIQ brought our vision to life seamlessly. They implemented our ideas quickly and executed them flawlessly. Since partnering with them, our contact rates have significantly improved, our conversions have increased, and our overall business is thriving. We're deeply grateful for this collaboration and look forward to continuing our work together on future endeavors!" - Tim, Lit Financial "I genuinely don't know enough ways to thank the entire outboundIQ team. I inherited a domain riddled with mistakes, tangled beyond belief, and I had essentially planned to scrap the whole thing and start over. That's when this team, led by Jessica Clay's brilliance, took over to understand exactly what I wanted to create and completely revitalized my domain. We are all beyond thankful as they continue to consult for us to this day and I see no reason to stop. Thank you, Jessica, Jason, Rudy, Bruno, Sandy and everyone who gets the pleasure of working with these domain geniuses!" - Michael, Lifetime Home Remodeling A Holistic Approach to Outbound Excellence Creating a competitive, consumer-focused outreach program requires more than just advanced technology. As outboundIQ explains, a thriving contact center functions like a high-performing racing team: outboundIQ's professional services team brings these critical elements together, ensuring clients achieve best-in-class outbound operations that prioritize consumer experience while maintaining a competitive edge. A Call to Collaboration With its new CIP certification, outboundIQ invites businesses to explore select partnership opportunities and projects to reimagine their contact center operations. Whether through expedited implementations or ongoing strategic consulting, outboundIQ is committed to driving measurable results for its clients. About outboundIQ outboundIQ delivers optimized, outbound-focused contact center implementations, combining years of Five9 expertise with cutting-edge strategies to help businesses achieve exceptional outreach outcomes. As a Five9 Certified Implementation Partner, outboundIQ provides tailored solutions to meet the unique needs of modern organizations. About Five9 Five9 is a digital enterprise's leading cloud contact center and software provider. The Five9 Intelligent CX Platform is reliable, secure, compliant, and scalable, designed to create exceptional personalized customer experiences. www.five9.com Media contact: Sandy Tafur Phone: 404-660-5314 mail: sandy@outboundiq.com View original content to download multimedia: https://www.prnewswire.com/news-releases/outboundiq-achieves-certified-implementation-partner-cip-status-with-five9-302339797.html SOURCE outboundIQ
PALO ALTO, Calif., Dec. 27, 2024 (GLOBE NEWSWIRE) -- Vincerx Pharma, Inc. VINC , a biopharmaceutical company aspiring to address the unmet medical needs of patients with cancer through paradigm-shifting therapeutics, today announced that it has entered into a binding term sheet for a proposed merger with Oqory, Inc., a privately-held, clinical-stage company developing ADCs for the treatment of multiple oncology indications. Upon completion of the proposed merger, Oqory, Inc. will merge with Vincerx Pharma, Inc. Post-closing, Oqory equity holders are expected to own approximately 95% of the combined entity, while Vincerx equity holders will hold about 5%. The transaction includes a minimum fully diluted equity value of $13.66 million for existing Vincerx stockholders at closing and, as a condition to the closing of the merger, completion of a concurrent offering of Vincerx equity securities of at least $20 million. Additionally, Oqory-designated investors will provide interim financing to Vincerx of $1.5 million in two tranches, approximately $1,000,000 of which was funded today through the issuance of common stock and pre-funded warrants along with accompanying common stock warrants and approximately $500,000 of which will be funded on or prior to January 31, 2025. The merger is subject to customary closing conditions, including due diligence, regulatory approvals, negotiation of a definitive merger agreement, stockholder approval from both parties, completion of the minimum $20 million financing, and the continued listing of Vincerx's common stock on Nasdaq. Vincerx is also implementing additional streamlining and cost-control measures, including a workforce reduction, as it pursues due diligence and transaction-related work. As part of this workforce reduction, Dr. Ahmed Hamdy, Chairman and Chief Executive Officer (CEO), has stepped down as CEO but will remain as Chairman. Dr. Raquel Izumi has stepped down as President and Chief Operations Officer and taken over as Acting CEO in a consulting capacity. Alexander Seelenberger has stepped down as Chief Financial Officer, and Kevin Hass, the Company's Vice President and Controller, has taken over as Acting Chief Financial Officer. Mr. Seelenberger has agreed to provide ongoing assistance in a consulting capacity to assist the Company as it pursues its strategic efforts. "This strategic transaction highlights Vincerx's commitment to develop ADCs with improved safety profiles that allow patients to thrive on—rather than endure—their cancer therapies," said Raquel Izumi, Ph.D., Acting Chief Executive Officer. "Oqory's anti-TROP2 ADC has shown favorable efficacy and safety in the clinic. Among approximately 150 treated patients, results include an 83% overall response rate and 100% disease control rate in first-line triple-negative breast cancer (TNBC; n=30). Unlike other TROP2 ADCs in Phase 3, no cases of interstitial lung disease or Grade 3 and above stomatitis have been reported. Oqory's Phase 3 studies of OQY-3258 are ongoing to confirm these promising findings." About OQY-3258 (also known as ESG401) OQY-3258 is Oqory's anti-TROP2 ADC with an optimized enzyme-dependent linker technology and an SN-38 payload with established efficacy and manageable side effect profile. OQY-3258 has completed Phase 1/2 development in over 150 patients with solid tumors, including metastatic HR+/HER2- and triple-negative breast cancer. OQY-3258 has shown efficacy in these patients, including reduction of brain metastasis and responses in heavily pretreated patients. To date, OQY-3258 has exhibited a differentiated safety profile vs. Trodelvy and other TROP2 ADCs in Phase 3 development. Notably, no interstitial lung disease or ocular surface events have been observed. Gastrointestinal effects have been mild and mainly Grade 1/2. Neutropenia and leukopenia have been the major AEs, which were manageable and did not result in discontinuation of study drug. OQY-3258 is being evaluated in a Phase 3 study as first-line treatment in patients with unresectable recurrent or metastatic triple-negative breast cancer ( NCT06732323 ) and in a Phase 3 study in patients with unresectable locally advanced or metastatic HR+/HER2- breast cancer ( NCT06383767 ). About Oqory, Inc. Oqory, Inc. is an innovator in the field of ADCs with expertise in advancing targeted cancer therapies. The Company's pipeline includes multiple ADC programs, with two currently in clinical development and several next-generation ADCs in preclinical stages. These programs are designed to address critical unmet needs in indications such as breast cancer, non-small cell lung cancer, small cell lung cancer, multiple myeloma, and other metastatic solid tumors. Powered by a proprietary ADC platform, Oqory is delivering therapies that have demonstrated promising efficacy and safety paving the way for improved patient outcomes. About Vincerx Pharma, Inc. Vincerx Pharma, Inc. is a clinical-stage biopharmaceutical company committed to developing differentiated and novel therapies to address the unmet medical needs of patients with cancer. Vincerx's pipeline consists of a next-generation ADC, VIP943, currently in Phase 1; a small molecule drug conjugate, VIP236, which has completed its Phase 1 study; a CDK9 inhibitor, enitociclib, which has completed a Phase 1 monotherapy study; a preclinical ADC, VIP924; and VersAptxTM, a versatile, next-generation bioconjugation platform. Vincerx is based in Palo Alto, California, and has a research subsidiary in Monheim, Germany. Forward-Looking Statements This press release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended (the Securities Act), and Section 21E of the Securities Exchange Act of 1934, as amended, that are intended to be covered by the "safe harbor" created by those sections. Forward-looking statements, which are based on certain assumptions and describe future plans, strategies, expectations and events, can generally be identified by the use of forward-looking terms such as "believe," "expect," "may," "will," "should," "would," "could," "suggest," "seek," "intend," "plan," "goal," "potential," "on-target," "on track," "project," "estimate," "anticipate," or other comparable terms. All statements other than statements of historical facts included in this press release are forward-looking statements. Forward-looking statements include, but are not limited to, the entry into a definitive merger agreement; the anticipated terms and closing of the merger, the $20 million equity investment, and the amount and timing of the interim financing; the expected ownership structure and value to Vincerx stockholders upon closing of the merger; the anticipated benefits of a merger transaction; and the clinical results of Oqory's product candidates. Forward-looking statements are neither historical facts nor assurances of future performance or events. Instead, they are based only on current beliefs, expectations, and assumptions regarding future business developments, future plans and strategies, projections, anticipated events and trends, the economy, and other future conditions. Forward-looking statements are subject to inherent uncertainties, risks, and changes in circumstances that are difficult to predict, many of which are outside Vincerx's control. Actual results, conditions, and events may differ materially from those indicated in the forward-looking statements. Therefore, you should not rely on any of these forward-looking statements. Important factors that could cause actual results, conditions, and events to differ materially from those indicated in the forward-looking statements include, but are not limited to, Vincerx's capital requirements, availability and sufficiency of capital, and cash runway; the ability of the parties to enter into a definitive merger agreement and the final terms thereof; the parties' ability to satisfy the conditions precedent to the merger, including stockholder approval; the closing of the merger; the risk that any definitive agreement is terminated after it is entered into but before consummation of any proposed merger;; Vincerx's reliance on receipt of interim funding; market acceptance of the combined company; risks associated with clinical development of the Vincerx and Oqory product candidates; general economic, financial, legal, political, and business conditions; and the risks and uncertainties set forth in Vincerx's Quarterly Report on Form 10-Q for the quarter ended September 30, 2024 and subsequent reports filed with the Securities and Exchange Commission by Vincerx. Forward-looking statements speak only as of the date hereof, and Vincerx disclaims any obligation to update any forward-looking statements. Vincerx and the Vincerx logo are trademarks of Vincerx. This press release also contains trademarks and trade names that are the property of their respective owners. Contacts: Gabriela Jairala Vincerx Pharma, Inc. gabriela.jairala@vincerx.com Totyana Simien Inizio Evoke Comms totyana.simien@inizioevoke.com © 2024 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.
Stock market today: Wall Street rises with Nvidia as bitcoin bursts above $99,000The NFL's security division is warning players to be aware of professional burglars targeting the homes of pro athletes. The Athletic reported Thursday that the NFL sent a memo to teams that outlines the threat. "The homes of professional athletes across multiple sports leagues have become increasingly targeted for burglaries by organized and skilled groups," read the memo, which was obtained by The Athletic. "Law enforcement officials have noted these groups appear to exploit team schedules to target athletes' homes on game days." NBC News reported Wednesday that law enforcement is working to figure out whether an international crime syndicate is involved. The Athletic reported that the memo includes tips for home security and also gives recommendations about the use of social media, such as not posting photos of items that would attract thieves. Players also learned via the memo how homes are targeted and how burglars enter. Mahomes hasn't said much about the burglary, other than to call it "disappointing" and "frustrating." "I can't get into too many of the details because the investigation is still ongoing," he said. "But obviously something that you don't want to happen to really anybody, but obviously yourself." It's not clear what was stolen from Mahomes' home in Belton, Mo., during the Oct. 6 incident. But Kelce apparently lost $20,000 in cash in the burglary at his home in Leawood, Kan., the following day when the Chiefs played the New Orleans Saints on "Monday Night Football," according to a police report. The burglary at the home of Milwaukee Bucks forward Bobby Portis in River Hills, Wis., occurred Nov. 2 during the Bucks' home game against the Cleveland Cavaliers, He said the perpetrators "took most of my prized possessions" and is offering a reward for the return of his property. "Any info that leads to the return of any of my belongings will be rewarded handsomely," Portis said. "Let me know, thank you." --Field Level Media
Central-Phenix City High School faces Hoover High School in the semifinal round of the AHSAA playoffs on Friday, Nov. 22, 2024, at 7 p.m. CT in Phenix-City, Alabama. Here’s how you can watch the game on NFHS Network. Watch: Central-Phenix City vs. Hoover LIVE STREAM How can I watch Central-Phenix City vs. Hoover? Fans can subscribe to NFHS Sports Network , a nationwide streaming platform for more than 9,000 high school sports. You can find the list of available schools here. How much does an NFHS subscription cost? Is there a free trial to NFHS Network? An annual subscription costs $79.99, or you can pay monthly for $11.99 per month. Can you watch NFHS on your phone or TV? NFHS Network is available on smart TVs like Apple TV, Roku, Amazon Fire and Google Chromecast, as well as on iOS and Android smartphones. Top 25 high school football rankings (MaxPreps) 1. Mater Dei (Santa Ana, California) 2. Milton (Milton, Georgia) 3. Duncanville (Duncanville, Texas) 4. Bishop Gorman (Las Vegas, Nevada) 5. Carrollton (Carrollton, Georgia) 6. North Shore (Houston, Texas) 7. St. John Bosco (Bellflower, California) 8. St. Frances Academy (Baltimore, Maryland) 9. North Crowley (Fort Worth, Texas) 10. Archbishop Spalding (Severn, Maryland) 11. Buford (Buford, Georgia) 12. Centennial (Corona, California) 13. Orange Lutheran (Orange, California) 14. Lakeland (Lakeland, Florida) 15. Chaminade-Madonna (Hollywood, Florida) 16. Mission Viejo (Mission Viejo, California) 17. Boyle County (Danville, Kentucky) 18. IMG Academy (Bradenton, Florida) 19. Venice (Venice, Florida) 20. Atascocita (Humble, Texas) 21. Corner Canyon (Draper, Utah) 22. Bergen Catholic (Oradell, New Jersey) 23. De La Salle (Concord, California) RECOMMENDED • nj .com Buford (GA) vs. Lowndes (GA) LIVE STREAM (11/22/24) | How to watch Georgia high school football playoff game Nov. 22, 2024, 6:00 p.m. Duncanville vs. Rockwall LIVE STREAM (11/22/24) | How to watch Texas high school football playoff game online Nov. 22, 2024, 6:00 p.m. 24. DeMatha (Hyattsville, Maryland) 25. DeSoto (DeSoto, Texas) Thank you for relying on us to provide the journalism you can trust.In wake of officer's death, West Yellowstone police offer aid for those grieving
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While my election-related columns about politics and the economy generated the most reader responses in recent weeks, I found the reaction to my column on direct primary care most interesting. In these arrangements, patients pay doctors directly, like in the old days, rather than through insurance. The topic tapped a vein of nostalgia with readers who remembered what health care was like 50 years ago, before the rise of interlinked networks of care systems and nationwide insurers. For others, the concept — in which patients essentially become members of a doctor’s practice and pay a flat monthly fee of around $70 to $90 — just seems practical. “We only need health insurance for major medical procedures. Health care would be much less expensive without it,” reader Mary O’Connor wrote. She then offered a plan for getting more people to use direct primary care physicians. “I suggest we start with public employees,” she wrote. “Take away their health insurance except for major medical procedures and give them an increase in pay. They can use this for doctor appointments. Doctors will lower their charges if they don’t have to wait for an insurance company to pay them.” Dr. Darrell Krieger, a physician in Crystal, wrote to point out a problem. “What is left unsaid in the article is the issue that primary care physicians are decreasing in number at an alarming rate, with no one to replace them, making access for patients increasingly difficult, particularly as older physicians such as myself retire,” he wrote. “This is a nationwide problem that is recognized within the medical field but gets little attention in the media,” he added. Though I didn’t mention it in the column, I talked with Dr. Laura Slings and her husband Steve, who runs the back office in her practice, about the broader numbers at stake. When she was working at one of the large health systems, Dr. Slings had more than 2,000 patients in her practice. She’s aiming for about 500 at her independent clinic. “If all these doctors leave the system and open direct primary care ... that’s going to contribute to the shortage, right?” Dr. Slings said. “It actually is a potential solution to the primary care crisis because so many primary care docs cannot continue to sustain what’s being asked of them right now. They’re retiring early. They’re burning out.” How, and whether, all this works out will take years, I suspect. My colleague Karen Tolkkinen last week wrote about the most acute shortage of doctors in Minnesota: dentists outside the metro area . Separately, several readers asked about something I left out of my Oct. 16 column on ninja gyms: whether kids are more prone to getting injured in them than a playground or school gym. Kids are kids, of course, and they’re out flinging themselves around in these places. At Ninjas United, the Maple Grove gym I visited, the padding is everywhere and there are coaches and spotters all around. “You’ll see we have some $800 mats called cloud mats and they’re phenomenal,” co-owner Chris Voigt said. His wife, Jen, who runs the gym, said she notices teenagers are more prone to sprains or strains because they need to warm up. “But they still remember being a kid when they didn’t need to warm up,” she said. “So some are a little more relaxed in their warm-ups, when they should be a little more focused during that.” This past week, several readers reacted to my column about the dramatic, ignominious end of Bremer Bank , the longtime St. Paul institution that sold to Indiana-based Old National, by noting that the bank’s beginning was just as dramatic. Before starting the bank and the charitable foundation that owned it, Otto Bremer and his brother Adolf in 1911 took over the Schmidt Brewing Co. from its founder, Jacob Schmidt. They built it into one of the nation’s largest by 1920, when prohibition started. Through the 1920s, Otto started to purchase banks and, as the Depression started, “pledged every asset he owned” to keep them shored up. That included his stocks in “eastern banks,” according to the Star Tribune’s obit of him in 1951. “The eastern stocks were lost by sale when additional margins in a declining market could not be furnished,” the obituary said. Finally, a good news update to a column I wrote at the start of the year urging Minnesota regulators to allow taller buildings with a single staircase. On Oct. 31, the technical advisory group responsible for updating the state’s building code unanimously approved a proposal that will allow single-stair residential buildings up to four stories. “This approval makes Minnesota the first among the new wave of states around the country moving in this direction to actually adopt a code change statewide,” said Cody Fischer, president of Footprint Development in Minneapolis.Maharashtra CM Oath-Taking Ceremony: Date, Time, Venue, Where To Watch And More About New Govt Formation