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golden empire jili download The volatile tribal district of Kurram witnessed another scene of carnage, death and destruction on 21 November 2024. On this fateful day, a convoy of about 200 vehicles was travelling from Parachinar to Peshawar when at about 1:20 PM, gunmen jumped out of their vehicles and poured deadly gunfire on the travelling vehicles on the road, to extinguish the lives of 40 innocent residents of Parachinar including women and children. The attacked convoy consisted of mostly Shia Muslim members of the community. According to local sources, this attack was in retaliation for a 12 October attack that had left 15 people dead, including two women and a child. No group has so far claimed responsibility, but it is very likely that the banned TTP is behind this atrocity, because it has been quite active in this region in the recent past. State security agencies are either responsible for criminal negligence or have made no efforts to curb the acts of violence in this sensitive area. Since July this year, over 80 people have been killed while travelling by road and the people of the region have protested, demanding peace and security. But the state agencies have so far failed miserably to provide relief to the people of the area. The government now must make it priority number one to secure this region, or else this scourge will most likely spill over and then sectarian outfits could exploit the situation to create tensions across the country Quite oblivious of the plight of these communities, today the federal government and the provincial authorities of KP province are embroiled in a bitter dispute because of the 24th November protest day announced by the PTI. Due to their infighting, both the federal and provincial authorities are least bothered about the security conditions in Kurram or other parts of KP. Government sources tend to express their indignation and condemnation of the acts of terrorism, and promises are made to deal with the terrorists with an iron hand and bring them to justice. But in practice, the poor residents of the areas are left to their own devices when bloodthirsty militants rule the roost. Kurram district is extremely sensitive because of the sectarian divide and its proximity to Afghanistan along with the presence of obscurantist militants of the TTP. So far the government has not been able to control militancy or to settle tribal disputes that explode into tribal vendettas. The government now must make it priority number one to secure this region, or else this scourge will most likely spill over to other areas of the province and then sectarian outfits could exploit the situation to create tensions across the length and breadth of the country. Elements responsible for the latest atrocity must be tracked down and punished and our state agencies must come up with practical plans for the security and safety of the people of Kurram or this violence could engulf the entire country. PBC Condemns Horrific Attack In Lower Kurram, Calls For Immediate Action The resurgence of violence has escalated since the TTP ended a fragile ceasefire agreement with the government in 2022 and vowed to intensify its attacks. The group's activity has added another layer of insecurity in a region already plagued by sectarian and tribal conflicts. The latest atrocity in Kurram is a stark reminder that the country is now at war with itself. Our brave soldiers are losing lives every day, and the enemy is not across the border but within the national boundaries. The hurried departure of the US forces from Afghanistan resulted in the Taliban control of Afghanistan and the Pakistani Prime Minister Imran Khan was the only world leader who openly welcomed the Taliban regime in Kabul and rejoiced at their victory declaring “The Taliban have broken the shackles of slavery.” Subsequently the then PTI-led federal government decided to release about 5,000 terrorists and militants of the TTP who had been languishing n Pakistani jails, and allowed them to settle down in the areas of their choice. An outdated and wrong concept of ‘strategic depth’ seems to be guiding our policy planners even today. The attitude and behaviour of the Talban regime in Kabul should be a lesson to scrap the old policies of seeking such ‘strategic depth’ and start with a clean slate regarding our policy towards the Afghan Taliban. The province of KP in the direct line of fire, and facing the brunt of the attacks by the militant forces of obscurantism and sectarianism. Far from the miscalculations of policy-makers, our soldiers on the ground are facing this danger with great courage and determination and almost everyday lives are being lost. So, far the total loss of lives at the hands of the militant forces of the Taliban has been more than the total loss of lives suffered in all the wars with the country’s traditional arch-nemesis India. It is now time to take the war to the enemy, hit them in their safe sanctuaries and nip the evil in the bud – before further damage is done to our state institutions and social fabric. According to the army chief, the army is now paying a price in blood because of the incompetence of political forces. This unfortunate state of affairs since 2021 has not been settled. Beginner’s Guide To Writing About Old Buildings In fact, the blame rests not just on the security establishment and federal governments. The provincial government of KP leaves much to be desired. The Chief Minister of the volatile province is neck deep in promoting the party agenda while criminally neglecting his role as an administrator of the province that is under threat by a bloody insurgency. When he devotes all his time to planning agitations against the federal authorities instead of fighting and curbing militancy and terrorism in his own province, the Chief Minister also becomes guilty of gross neglect.A new twist: The molecular machines that loop our chromosomes also twist DNA December 13, 2024 Delft University of Technology Scientists have discovered a new property of the molecular motors that shape our chromosomes. While six years ago they found that these so-called SMC motor proteins make long loops in our DNA, they now discovered that these motors also put significant twists into the loops that they form. These findings help us better understand the structure and function of our chromosomes. They also provide insight into how disruption of twisted DNA looping can affect health -- for instance, in developmental diseases like 'cohesinopathies'. Facebook Twitter Pinterest LinkedIN Email Scientists from the Kavli Institute of Delft University of Technology and the IMP Vienna Biocenter discovered a new property of the molecular motors that shape our chromosomes. While six years ago they found that these so-called SMC motor proteins make long loops in our DNA, they now discovered that these motors also put significant twists into the loops that they form. These findings help us better understand the structure and function of our chromosomes.They also provide insight into how disruption of twisted DNA looping can affect health -- for instance, in developmental diseases like 'cohesinopathies'. The scientists published their findings in Science Advances. The struggle of our cells Imagine trying to fit two meters of rope into a space much smaller than the tip of a needle -- that's the challenge every cell in your body faces when packing its DNA into its tiny nucleus. To achieve this, nature employs ingenious strategies, like twisting the DNA into coils of coils, so-called 'supercoils' (see pictures for a visualisation) and wrapping it around special proteins for compact storage. Small DNA loops regulate chromosome functions However, compaction isn't enough. Cells also need to regulate the chromosome structure to enable its function. For example, when genetic information needs to be accessed, the DNA is locally read off. In particular when it's time for a cell to divide, the DNA must first unpack, duplicate, and then properly separate into two new cells. Specialised protein machines called SMC complexes (Structural Maintenance of Chromosomes) play a critical role in these processes. Just a few years ago, scientists at Delft and other places discovered that these SMC proteins are molecular motors that make long loops in our DNA, and that these loops are the key regulators of chromosome function. A new twist In the lab of Cees Dekker at TU Delft, postdocs Richard Janissen and Roman Bath now provide clues that help to crack this puzzle. They deloped a new way to use 'magnetic tweezers' by which they could watch individual SMC proteins make looping steps in DNA. Importantly, they were also able to resolve if the SMC protein would change the twist in the DNA. And strikingly, the team found that it did: the human SMC protein cohesin does indeed not only pull DNA into a loop, but also twists the DNA in a left-handed way by 0.6 turns in each step of creating the loop. A glimpse into the evolution of SMC proteins What's more, the team found that this twisting action isn't unique to humans. Similar SMC proteins in yeast behave the same way. Strikingly, all the various types of SMC proteins from human and yeast add the same amount of twist -- they turn DNA 0.6 times at every at every DNA loop extrusion step. This shows that the DNA extrusion and twisting mechanisms stayed the same for very long times during evolution. No matter whether DNA is looped in humans, yeast, or any other cell -- nature employs the same strategy. Essential clues These new findings will provide essential clues for resolving the molecular mechanism of this new type of motor. Additionally, they make clear that DNA looping also affects the supercoiling state of our chromosomes, which directly affects processes like gene expression. Finally, these SMC proteins are related to various diseases such as Cornelia de Lange Syndrome, and a better understanding of these processes is vital for tracking down the molecular origins of these serious illnesses. Story Source: Materials provided by Delft University of Technology . Note: Content may be edited for style and length. Journal Reference : Cite This Page :No. 2 Ohio State takes control in the 2nd half and runs over No. 5 Indiana 38-15 COLUMBUS, Ohio (AP) — Will Howard passed for two touchdowns and rushed for another, TreVeyon Henderson ran for a score and No. 2 Ohio State beat previously undefeated No. 5 Indiana 38-15. All Ohio State has to do now is beat Michigan at home next Saturday and it will earn a return to the Big Ten championship game for the first time since 2020 and get a rematch with No. 1 Oregon. The Ducks beat Ohio State 32-31 in a wild one back on Oct. 12. Man City routed 4-0 by Tottenham in fifth-straight defeat as crisis deepens for Pep Guardiola What started as an evening of celebration for Manchester City ended with the four-time defending Premier League champion falling to a fifth-straight loss in all competitions and facing a deepening crisis in a season that is threatening to unravel. A 4-0 defeat to Tottenham left City five points behind league leader Liverpool, having played a game more. Two goals from James Maddison inside 20 minutes at the Etihad Stadium stunned the home crowd. Pedro Porro scored a third for Tottenham after halftime. Brennan Johnson added a fourth in the third minute of stoppage time. City manager Pep Guardiola signed a two-year contract extension this week. Chelsea, Arsenal and Brighton all won and closed the gap on Liverpool to six points. Florida knocks No. 9 Ole Miss out of College Football Playoff contention, 24-17 in the Swamp GAINESVILLE, Fla. (AP) — DJ Lagway threw two touchdown passes, Montrell Johnson ran for 127 yards and a score, and Florida upset No. 9 Mississippi 24-17 on Saturday to knock the Rebels out of College Football Playoff contention. The Gators beat ranked teams in consecutive weeks for the first time since 2008 and became bowl eligible. The late-season spurt provided another vote of confidence for coach Billy Napier, who is expected back for a fourth season. Ole Miss lost for the first time in four games and surely will drop out of the 12-team playoff picture. Jennings has 3 TDs as No. 13 SMU routs Virginia 33-7 to clinch a spot in the ACC title game CHARLOTTESVILLE, Va. (AP) — Kevin Jennings threw for a career-high 323 yards and two touchdowns and ran for another, and No. 13 SMU clinched a spot in the Atlantic Coast Conference championship game by routing Virginia 33-7. Isaiah Smith and Jared Harrison-Hunte each had two sacks to help the Mustangs extend their winning streak to eight. They would earn an automatic bid into the expanded College Football Playoff by beating 11th-ranked Miami or 17th-ranked Clemson in the ACC title game on Dec. 7 in Charlotte, North Carolina. UVa must beat rival Virginia Tech next week to become bowl eligible. No. 11 Miami pulls away late to beat Wake Forest 42-14 and move one win from the ACC title game MIAMI GARDENS, Fla. (AP) — Cam Ward passed for 280 yards and threw two touchdowns to Jacolby George on another record-breaking day, Mishael Powell ran an interception back 76 yards for a touchdown and No. 11 Miami pulled away late to beat Wake Forest 42-14. The 10-1 Hurricanes can clinch a berth in the ACC title game with a win at Syracuse next weekend. Ward completed 27 of 38 passes, plus ran for a score. Demond Claiborne had a 100-yard kickoff return for a touchdown for 4-7 Wake Forest. No. 24 Illinois stuns Rutgers on Bryant's 40-yard TD reception with 4 seconds left PISCATAWAY, N.J. (AP) — Luke Altmyer found Pat Bryant for a catch-and-run, 40-yard touchdown pass with 4 seconds left, sending No. 24 Illinois to a wild 38-31 victory over Rutgers. Illinois was down 31-30 when it sent long kicker Ethan Moczulski out for a desperation 58-yard field goal with 14 seconds to go. Rutgers coach Greg Schiano then called for a timeout right before Moczulski’s attempt was wide left and about 15 yards short. After the missed field goal was waved off by the timeout, Illinois coach Bret Bielema sent his offense back on the field. Altmyer hit Bryant on an in cut on the left side at the 22, and he continued across the field and scored untouched. Hidalgo leads No. 6 Notre Dame over JuJu Watkins and third-ranked USC 74-61 in big matchup out West LOS ANGELES (AP) — Hannah Hidalgo scored 24 points and No. 6 Notre Dame defeated JuJu Watkins and third-ranked Southern California 74-61 in a marquee matchup on the West Coast. Hidalgo had six rebounds and eight assists in front of several WNBA scouts. Olivia Miles added 20 points for the Fighting Irish, who improved to 5-0. Watkins finished with 24 points, six rebounds and five assists for the Trojans, who fell to 4-1. The Irish came out strong, taking a 20-10 lead in the first quarter, when Hidalgo had 11 points. They never looked back and stayed poised when USC came within three points three different times. Andy Murray will coach Novak Djokovic through the Australian Open Recently retired Andy Murray will team up with Novak Djokovic, working with him as a coach through the Australian Open in January. Murray’s representatives put out statements from both players on Saturday. Djokovic is a 24-time Grand Slam champion who has spent more weeks at No. 1 than any other player in tennis history. Murray won three major trophies and two Olympic singles gold medals who finished 2016 atop the ATP rankings. He retired as a player after the Paris Summer Games in August. Jannik Sinner and Matteo Berrettini lift Italy past Australia and back to the Davis Cup final MALAGA, Spain (AP) — Top-ranked Jannik Sinner and Matteo Berrettini won their singles matches to lift defending champion Italy past Australia 2-0 and back into the Davis Cup final. Sinner extended his tour-level winning streak to 24 sets in a row by beating No. 9 Alex de Minaur 6-3, 6-4 on Saturday on an indoor hard court in Malaga, Spain. That came after Berrettini came back to defeat Thanasi Kokkinakis 6-7 (6), 6-3, 7-5. Italy will meet first-time finalist Netherlands on Sunday for the title. The Dutch followed up their victory over Rafael Nadal and Spain in the quarterfinals by eliminating Germany on Friday. Argentina's Racing wins its first Copa Sudamericana championship by beating Brazil's Cruzeiro 3-1 ASUNCION, Paraguay (AP) — Gaston Martirena and Adrian Martinez scored first-half goals as Argentina’s Racing won its first Copa Sudamericana championship by beating Brazil’s Cruzeiro 3-1 in the final on Saturday. Martirena opened the scoring in the 15th minute and Martinez added a goal five minutes later to help give “La Academia” its first international title since 1988 when it won the Supercopa Sudamericana. Roger Martinez sealed the victory with a goal in the 90th. “Maravilla” Martinez scored 10 goals in 13 matches and finished as the top scorer in the competition. Kaio Jorge scored in the 52nd for Cruzeiro.AP Sports SummaryBrief at 6:24 p.m. EST

NoneLennar Corporation's Fourth Quarter Earnings Conference Call to Be Broadcast Live on the InternetATLANTA (AP) — the peanut farmer who won the presidency in the wake of the Watergate scandal and Vietnam War, endured humbling defeat after one tumultuous term and then redefined life after the White House as a global humanitarian, has died. years old. The died on Sunday, more than a year after entering , at his home in the small town of Plains, Georgia, where he and his wife, who , spent most of their lives, The Carter Center said. Businessman, Navy officer, evangelist, politician, negotiator, author, woodworker, citizen of the world — Carter forged a path that still challenges political assumptions and stands out among the 45 men who reached the nation’s highest office. The 39th president leveraged his ambition with a keen intellect, deep religious faith and prodigious work ethic, and well into his 90s. “My faith demands — this is not optional — my faith demands that I do whatever I can, wherever I am, whenever I can, for as long as I can, with whatever I have to try to make a difference,” Carter once said. A moderate Democrat, as a little-known Georgia governor with a broad smile, outspoken Baptist mores and technocratic plans reflecting his education as an engineer. His no-frills campaign depended on public financing, and his promise not to deceive the American people resonated after Richard Nixon’s disgrace and U.S. defeat in southeast Asia. “If I ever lie to you, if I ever make a misleading statement, don’t vote for me. I would not deserve to be your president,” Carter repeated before narrowly beating Republican incumbent Gerald Ford, who had lost popularity pardoning Nixon. Carter governed amid Cold War pressures, turbulent oil markets and social upheaval over racism, women’s rights and America’s global role. His most acclaimed achievement in office was a Mideast peace deal that he brokered by keeping Egyptian President Anwar Sadat and Israeli Prime Minister Menachem Begin at the bargaining table for 13 days in 1978. That Camp David experience inspired the post-presidential center where Carter would establish so much of his legacy. Yet Carter’s electoral coalition splintered under double-digit inflation, gasoline lines and the 444-day hostage crisis in Iran. His bleakest hour came when eight Americans died in a failed hostage rescue in April 1980, helping to ensure his landslide defeat to Republican Ronald Reagan. Carter acknowledged in his 2020 “White House Diary” that he could be “micromanaging” and “excessively autocratic,” complicating dealings with Congress and the federal bureaucracy. He also turned a cold shoulder to Washington’s news media and lobbyists, not fully appreciating their influence on his political fortunes. “It didn’t take us long to realize that the underestimation existed, but by that time we were not able to repair the mistake,” Carter told historians in 1982, suggesting that he had “an inherent incompatibility” with Washington insiders. Carter insisted his overall approach was sound and that he achieved his primary objectives — to “protect our nation’s security and interests peacefully” and “enhance human rights here and abroad” — even if he fell spectacularly short of a second term. Ignominious defeat, though, allowed for renewal. The Carters founded The Carter Center in 1982 as a first-of-its-kind base of operations, asserting themselves as international peacemakers and champions of democracy, public health and human rights. “I was not interested in just building a museum or storing my White House records and memorabilia,” Carter wrote in a memoir published after his 90th birthday. “I wanted a place where we could work.” That work included easing nuclear tensions in North and South Korea, helping to avert a U.S. invasion of Haiti and negotiating cease-fires in Bosnia and Sudan. By 2022, The Carter Center had declared at least 113 elections in Latin America, Asia and Africa to be free or fraudulent. Recently, the center as well. Carter’s stubborn self-assuredness and even self-righteousness proved effective once he was unencumbered by the Washington order, sometimes to the point of . He went “where others are not treading,” he said, to places like Ethiopia, Liberia and North Korea, where he secured the release of an American who had wandered across the border in 2010. “I can say what I like. I can meet whom I want. I can take on projects that please me and reject the ones that don’t,” Carter said. He announced an arms-reduction-for-aid deal with North Korea without clearing the details with Bill Clinton’s White House. He openly criticized President George W. Bush for the 2003 invasion of Iraq. He also criticized America’s approach to Israel with his 2006 book “Palestine: Peace Not Apartheid.” And he repeatedly countered U.S. administrations by insisting North Korea should be included in international affairs, a position that most aligned Carter Among the center’s many public health initiatives, Carter vowed to eradicate the guinea worm parasite during his lifetime, and Cases dropped from millions in the 1980s to nearly a handful. With hardhats and hammers, the Carters also built homes with Habitat for Humanity. The Nobel committee’s 2002 Peace Prize cites his “untiring effort to find peaceful solutions to international conflicts, to advance democracy and human rights, and to promote economic and social development.” Carter should have won it alongside Sadat and Begin in 1978, the chairman added. Carter accepted the recognition saying there was more work to be done. “The world is now, in many ways, a more dangerous place,” he said. “The greater ease of travel and communication has not been matched by equal understanding and mutual respect.” Carter’s globetrotting took him to remote villages where he met little “Jimmy Carters,” so named by admiring parents. But he spent most of his days in the same one-story Plains house — expanded and guarded by Secret Service agents — where they lived before he became governor. He regularly at Maranatha Baptist Church until his mobility declined and the coronavirus pandemic raged. Those sessions drew visitors from around the world to the small sanctuary where Carter will receive his final send-off after a state funeral at Washington’s National Cathedral. The common assessment that he was a rankled Carter and his allies. His prolific post-presidency gave him a brand above politics, particularly for Americans too young to witness him in office. But Carter also lived long enough to see biographers and historians reassess his White House years more generously. His record includes the deregulation of key industries, reduction of U.S. dependence on foreign oil, cautious management of the national debt and notable legislation on the environment, education and mental health. He focused on human rights in foreign policy, . He acknowledged America’s historical imperialism, pardoned Vietnam War draft evaders and relinquished control of the Panama Canal. He normalized relations with China. “I am not nominating Jimmy Carter for a place on Mount Rushmore,” Stuart Eizenstat, Carter’s domestic policy director, wrote in a 2018 book. “He was not a great president” but also not the “hapless and weak” caricature voters rejected in 1980, Eizenstat said. Rather, Carter was “good and productive” and “delivered results, many of which were realized only after he left office.” Madeleine Albright, a national security staffer for Carter and Clinton’s secretary of state, wrote in Eizenstat’s forward that Carter was “consequential and successful” and expressed hope that “perceptions will continue to evolve” about his presidency. “Our country was lucky to have him as our leader,” said Albright, Jonathan Alter, who penned a comprehensive Carter biography published in 2020, said in an interview that Carter should be remembered for “an epic American life” spanning from a humble start in a home with no electricity or indoor plumbing through decades on the world stage across two centuries. “He will likely go down as one of the most misunderstood and underestimated figures in American history,” Alter told The Associated Press. James Earl Carter Jr. was born Oct. 1, 1924, in Plains and spent his early years in nearby Archery. His family was a minority in the mostly Black community, decades before the civil rights movement played out at the dawn of Carter’s political career. Carter, who campaigned as a moderate on race relations but governed more progressively, talked often of the influence of his Black caregivers and playmates but also noted his advantages: His land-owning father sat atop Archery’s tenant-farming system and owned a main street grocery. , would become a staple of his political campaigns. Seeking to broaden his world beyond Plains and its population of fewer than 1,000 — then and now — Carter won an appointment to the U.S. Naval Academy, graduating in 1946. That same year another Plains native, a decision he considered more important than any he made as head of state. She shared his desire to see the world, sacrificing college to support his Navy career. Carter climbed in rank to lieutenant, but then his father was diagnosed with cancer, so the submarine officer set aside his ambitions of admiralty and moved the family back to Plains. even as she dived into the peanut business alongside her husband. Carter again failed to talk with his wife before his first run for office — he later called it “inconceivable” not to have consulted her on such major life decisions — but this time, she was on board. “My wife is much more political,” Carter told the AP in 2021. He won a state Senate seat in 1962 and its back-slapping, deal-cutting ways. He ran for governor in 1966 — losing to arch-segregationist Lester Maddox — and then immediately focused on the next campaign. Carter had spoken out against church segregation as a Baptist deacon and opposed racist “Dixiecrats” as a state senator. Yet as a local school board leader in the 1950s he had not pushed to end school segregation even after the Supreme Court’s Brown v. Board of Education decision, despite his private support for integration. And in 1970, Carter ran for governor again as the more conservative Democrat against Carl Sanders, a wealthy businessman Carter mocked as “Cufflinks Carl.” Sanders never forgave him for anonymous, race-baiting flyers, which Carter disavowed. Ultimately, Carter won his races by attracting both Black voters and culturally conservative whites. Once in office, he was more direct. “I say to you quite frankly that the time for racial discrimination is over,” he declared in his 1971 inaugural address, setting a new standard for Southern governors that landed him on the cover of Time magazine. His statehouse initiatives included environmental protection, boosting rural education and overhauling antiquated executive branch structures. He proclaimed Martin Luther King Jr. Day in the slain civil rights leader’s home state. And he decided, as he received presidential candidates in 1972, that they were In 1974, he ran Democrats’ national campaign arm. Then he declared his own candidacy for 1976. An Atlanta newspaper responded with the headline: “Jimmy Who?” and Georgia supporters camped out in Iowa and New Hampshire, establishing both states as presidential proving grounds. His first Senate endorsement: a young first-termer from Delaware named Joe Biden. Yet it was Carter’s ability to navigate America’s complex racial and rural politics that cemented the nomination. He swept the Deep South that November, the last Democrat to do so, as many white Southerners shifted to Republicans in response to civil rights initiatives. A self-declared “born-again Christian,” Carter drew snickers by referring to Scripture in a Playboy magazine interview, saying he “had looked on many women with lust. I’ve committed adultery in my heart many times.” The remarks gave Ford a new foothold and television comedians pounced — including NBC’s new “Saturday Night Live” show. But voters weary of cynicism in politics found it endearing. Carter chose Minnesota Sen. as his running mate on a “Grits and Fritz” ticket. In office, he elevated the vice presidency and the first lady’s office. Mondale’s governing partnership was a model for influential successors Al Gore, Dick Cheney and Biden. Rosalynn Carter was one of the most involved presidential spouses in history, welcomed into Cabinet meetings and huddles with lawmakers and top aides. The Carters presided with uncommon informality: He used his nickname “Jimmy” even when taking the oath of office, carried his own luggage and tried to silence the Marine Band’s “Hail to the Chief.” They bought their clothes off the rack. Carter wore a cardigan for a White House address, urging Americans to conserve energy by turning down their thermostats. Amy, the youngest of four children, attended District of Columbia public school. Washington’s social and media elite scorned their style. But the larger concern was that “he hated politics,” according to Eizenstat, leaving him nowhere to turn politically once economic turmoil and foreign policy challenges took their toll. Carter partially deregulated the airline, railroad and trucking industries and established the departments of Education and Energy, and the Federal Emergency Management Agency. He designated millions of acres of Alaska as national parks or wildlife refuges. He appointed a then-record number of women and nonwhite people to federal posts. He never had a Supreme Court nomination, but he elevated civil rights attorney to the nation’s second highest court, positioning her for a promotion in 1993. He appointed Paul Volker, the Federal Reserve chairman whose policies would help the economy boom in the 1980s — after Carter left office. He built on Nixon’s opening with China, and though he tolerated autocrats in Asia, pushed Latin America from dictatorships to democracy. But he couldn’t immediately tame inflation or the related energy crisis. And then came Iran. After he admitted the exiled Shah of Iran to the U.S. for medical treatment, the American Embassy in Tehran was overrun in 1979 by followers of the Ayatollah Ruhollah Khomeini. Negotiations to free the hostages broke down repeatedly ahead of the failed rescue attempt. The same year, Carter signed SALT II, the new strategic arms treaty with Leonid Brezhnev of the Soviet Union, only to pull it back, impose trade sanctions and order a U.S. boycott of the Moscow Olympics after the Soviets invaded Afghanistan. Hoping to instill optimism, he delivered what the media dubbed his “malaise” speech, although he didn’t use that word. He declared the nation was suffering “a crisis of confidence.” By then, many Americans had lost confidence in the president, not themselves. Carter campaigned sparingly for reelection because of the hostage crisis, instead for the Democratic nomination. Carter famously said he’d “kick his ass,” but was hobbled by Kennedy as Reagan rallied a broad coalition with “make America great again” appeals and asking voters whether they were “better off than you were four years ago.” Reagan further capitalized on Carter’s lecturing tone, eviscerating him in their lone fall debate with the quip: “There you go again.” Carter lost all but six states and Republicans rolled to a new Senate majority. Carter successfully negotiated the hostages’ freedom after the election, but in one final, bitter turn of events, Tehran waited until hours after Carter left office to let them walk free. At 56, Carter returned to Georgia with “no idea what I would do with the rest of my life.” Four decades after launching The Carter Center, he still talked of unfinished business. “I thought when we got into politics we would have resolved everything,” Carter told the AP in 2021. “But it’s turned out to be much more long-lasting and insidious than I had thought it was. I think in general, the world itself is much more divided than in previous years.” Still, he affirmed what he said when he underwent treatment for a in his 10th decade of life. “I’m perfectly at ease with whatever comes,” . “I’ve had a wonderful life. I’ve had thousands of friends, I’ve had an exciting, adventurous and gratifying existence.” ___ Former Associated Press journalist Alex Sanz contributed to this report.

Losing weight and having a lean physique is a desire for many, nevertheless, for most, it stays just that — a dream. Have you ever wondered why? Why do some people seem to lose weight effortlessly, while others fight their entire lives? Why don't healthy nutrition and everyday exercise always produce the expected results? If you've heard that it's due to metabolism or a slow metabolic rate, you're half correct. But have you considered why your body's metabolism is sluggish in the first place? Diabetes, thyroid problems, a sedentary lifestyle, stress and other hormonal disorders are common causes of slow metabolism. However, there is a cause that frequently goes unnoticed: low mitochondrial levels. Mitochondria are the cells' energy powerhouses, transforming food into energy. When your mitochondria levels are inadequate, your body's capacity to effectively burn fat suffers, leaving you with obstinate body weight and a slew of other health issues. Is there no solution? 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It comes in the form of an easy-to-take capsule, making your daily routine more convenient and simple. The formula is non-addictive, so consumers can start and stop without worrying about reliance. Mitolyn is made in an FDA-registered and GMP-certified facility, ensuring adequate levels of quality and safety. This dedication to perfection has made it a popular choice for people seeking long-term weight loss and better overall health. Mitolyn is more than just a supplement; it's a lifestyle update that can allow you to take control of your weight reduction journey and live a better, more active life. Get started with Mitolyn today! Importance Of Healthy Mitochondria Levels Mitochondria, sometimes known as the "powerhouses of the cell," play an important part in maintaining a healthy weight. When their function is disrupted, a series of issues arise, making weight management difficult. One of the most serious concerns associated with damaged mitochondria is the body's inability to burn fat efficiently. Mitochondria turn stored calories and fat into energy. When these tiny structures are damaged, fat oxidation decreases, resulting in persistent weight gain that nutrition and physical activity alone cannot reverse. Low mitochondrial levels also result in lower energy generation, which has a direct impact on physical activity. Individuals with poor mitochondrial health frequently feel fatigued, making it harder to maintain a vigorous routine or engage in regular workouts. This lack of mobility exacerbates weight growth, resulting in an endless cycle. Furthermore, damaged mitochondria cause hormonal abnormalities since they regulate metabolic hormones. Disruptions in these hormones can cause increased hunger, poor satiety, and a tendency to retain fat rather than burn it. Chronic inflammation and oxidative stress are two additional problems linked with mitochondrial dysfunction. These factors not only impede metabolism but also encourage the storage of visceral fat, raising the risk of obesity-related illnesses. Without addressing these underlying causes, maintaining a healthy body weight is extremely impossible. Mitolyn is a science-backed, novel approach to weight loss that targets a primary reason that most fat management treatments overlook: low mitochondrial levels. These little powerhouses within your cells play an important part in your body's capacity to burn fat, generate energy, and maintain overall health. But how does Mitolyn do this? Mitolyn's success is based on its capacity to support and possibly increase the activity of mitochondria. Mitochondria transform the food you ingest into energy, known as ATP. This energy powers everything, from muscular contraction to brain activity. Low mitochondrial levels reduce energy generation, delay fat burning and cause undesirable weight gain. Mitolyn works to rejuvenate these cellular powerhouses, potentially helping your body burn fat more efficiently and produce the energy it requires to survive. Mitolyn is a holistic health supplement that does more than just help you lose weight. It can help promote cholesterol balance and may improve circulation, both of which benefit heart health. The mixture can also improve immune function, allowing your body to fight off infections more efficiently. It may help improve skin, liver and digestive health, possibly resulting in a more vibrant and energetic lifestyle. Chronic stress is a silent impediment to successful weight management. Mitolyn contains substances that may help control stress hormones, boost mood and promote mental clarity. Mitolyn can help promote the smoothest possible weight loss path by addressing both physical and mental well-being. Researchers discovered that decreased mitochondrial levels are a common cause in obese people. Mitolyn builds on this discovery by addressing the cellular basis of energy and fat metabolism. It's a comprehensive program designed to help you accomplish not only weight loss but also total energy and wellness. Click here to check out the official website for Mitolyn >>> Customers who have tried Mitolyn have shared remarkable transformation tales, emphasizing the product's effectiveness in helping them meet their weight loss goals. Some customers report significant weight loss, generally in the 30-40 pound range, which they struggled to attain with traditional approaches. The most frequently claimed effects include increased energy, enhanced metabolism, and greater confidence in their appearance. One common topic in evaluations is the desire to better one's lifestyle. Customers frequently report feeling more active and capable of participating in daily tasks that were earlier laborious. Mitolyn appears to help more than just weight loss — it helps improve general well-being. Many purchasers prefer multi-bottle bundles, particularly the six-bottle option, because they allow for more consistent use and provide better value. This demonstrates users' belief in Mitolyn's capacity to produce long-term outcomes. Some customers even say that Mitolyn re-energized their metabolism after years of stagnation, allowing them to burn stubborn belly fat and break through painful weight plateaus. Overall, consumers feel empowered and driven, with Mitolyn playing a key role in their quest for better health and happiness. Mitolyn is unique in terms of formulation. It is created using plant-based compounds, vitamins, and minerals. After a thorough research and examination, here are some of the main Mitolyn ingredients: Rhodiola is a potent adaptogen known for its potential ability to battle both physical and mental stress, making it a crucial element in Mitolyn. Stress frequently disturbs the body's metabolism, resulting in weight gain and energy depletion. Rhodiola works by improving mitochondrial activity, increasing energy output, and promoting fat metabolism . It also can regulate cortisol levels, which reduces stress-induced cravings and impulsive eating. Rhodiola may also boost endurance and stamina, allowing you to perform better throughout the exercise. This powerful herb keeps your body in peak condition for effective weight management by addressing both mental and physical pressures. Amla, commonly referred to as Indian gooseberry, is a high-antioxidant, vitamin C-rich superfood. This superfruit promotes healthy metabolism by lowering oxidative stress in mitochondria, allowing them to function more efficiently. Amla improves digestion and detoxification, which are essential for a healthy weight. Its anti-inflammatory qualities contribute to the reduction of chronic inflammation, which is frequently associated with persistent fat storage. Furthermore, Amla promotes greater absorption of nutrients, ensuring that your body receives the necessary components for energy production. Amla is an important ingredient in Mitolyn's weight loss recipe because of its capacity to potentially enhance metabolic health as well as cell function. Schisandra is a multi-purpose herb that promotes mitochondrial health by increasing energy output and decreasing weariness. It is well-known for its adaptogenic characteristics, which aid in the body's ability to cope with stress, a typical obstacle to weight loss. Schisandra also improves liver function by assisting in the detoxification processes required for proper metabolism. Its strong antioxidant concentration prevents oxidative stress and maintains mitochondrial integrity. Furthermore, Schisandra regulates blood sugar levels, lowering cravings and encouraging consistent energy. This substance keeps your body energized and concentrated during your weight-loss journey. Get Mitolyn now while it's on sale - limited time only! Maqui Berry contains a high concentration of antioxidants, especially anthocyanins, which shield mitochondria from oxidative stress. This superfruit improves fat metabolism by promoting healthy production of energy at the cellular level . Maqui Berry's anti-inflammatory characteristics also help to promote healthy metabolism, lowering the danger of fat storage caused by chronic inflammation. Furthermore, its capacity to regulate blood sugar levels reduces spikes and crashes, which aids in the control of appetite and cravings. Maqui Berry, with its numerous metabolic benefits, is an important component of Mitolyn's composition. Haematococcus is best recognized for its high levels of astaxanthin, a powerful antioxidant that promotes mitochondrial function. Astaxanthin protects mitochondria from oxidative damage , resulting in maximum energy generation and fat-burning capacity. This component also improves cardiovascular health by supporting healthy blood flow, which is required for nutrient delivery and waste disposal at the cellular level. Haematococcus decreases inflammation, which is a major contributor to metabolic slowing and weight gain. Its unique capacity to increase cellular energy makes it an essential component of Mitolyn, helping to promote efficient fat metabolism and general health. Theobroma cacao, sometimes known as the "food of the gods," is an organic source of flavonoids and magnesium, each of which improves mitochondrial function. It stimulates energy generation by boosting blood flow to cells, ensuring that mitochondria receive vital nutrients. Theobroma Cacao also offers mood-enhancing qualities , lowering stress and preventing emotional eating. Its ability to regulate blood sugar levels reduces insulin surges that cause fat storage. Theobroma Cacao enhances Mitolyn's weight management strategy by promoting metabolic health as well as emotional well-being. Mitolyn is a low-cost weight loss supplement that can help anyone battling with excess fat. To ensure quality and genuineness, the manufacturers offer it exclusively through the official website . This removes intermediaries, lowers costs and prevents phony goods from reaching the market. Customers who purchase directly receive real Mitolyn with guaranteed quality, safe payment options, and exclusive savings and multi-bottle bundles for long-term benefits. Let’s understand its pricing structure: Purchase one Mitolyn bottle: $59 + Delivery Charges Purchase three Mitolyn bottles: $147 + Free Bonuses + Delivery Charges Purchase six Mitolyn bottles: $234 + Free Bonuses + Delivery Charges Mitolyn provides adjustable packages to meet various demands and weight loss goals. The single-bottle option is suitable for first-time users who want to evaluate the supplement's efficacy. For those looking for constant progress and visible results, the three-bottle box is an excellent choice since it delivers enough supplies to see consistent benefits. However, for strong, long-term results and the best value, the six-bottle bundle is highly recommended. This option is ideal for people who are determined to lose significant weight and maintain a healthy lifestyle over time. All packages offer complimentary bonuses, which increase the overall worth of the purchase. By selecting a multi-bottle package, consumers ensure continuous use, increasing their chances of achieving long-term health and weight transformation. 100% Satisfaction Guarantee Mitolyn has a 100% satisfaction promise and a 90-day money-back guarantee, allowing users peace of mind to try it risk-free. This policy enables individuals to test Mitolyn's efficacy without incurring financial costs. If users are dissatisfied with the outcomes, they may request a full refund within 90 days after purchase. Customers can simply contact the support team by emailing Contact@mitolyn.com or calling 1800-390-6035. This simple approach assures that everyone can enjoy Mitolyn's benefits with total confidence, making it a trustworthy and customer-focused weight loss option. You won't find a better deal on Mitolyn anywhere else! Free Bonuses With Mitolyn Fat Burner When users purchase three or six bottles of Mitolyn, they get free access to their bonus items. These are eBooks worth $100+, but you get them for free with Mitolyn. Here are these eBooks are about: The 1-Day Kickstart Detox is a strong guide that will reset your body and prepare it for successful weight loss. This ebook, packed with simple recipes and natural detox strategies, will help you remove toxins, minimize bloating, and raise your energy levels in just 24 hours. It works well with Mitolyn, ensuring that your body is in optimal condition to get the benefits of the supplement. Whether you're just starting out on your weight loss journey or need a quick boost, this detox regimen can revive your system and put you on track for success. Renew You is an inspirational ebook that focuses on improving your mental and emotional health while you lose weight. It provides practical ways for coping with stress, improving mood, and developing an optimistic mindset, addressing the often-overlooked psychological obstacles to accomplishing fitness goals. This book supports Mitolyn by providing ideas on mindfulness, self-care routines, and stress management to keep you motivated and balanced. Renew You helps you not only alter your body but also develop your confidence and mental toughness, resulting in a comprehensive approach to long-term health and well-being. Mitolyn provides a different perspective on weight loss, focusing on mitochondria to help your body reach its full potential. It's more than just a quick fix; it's a tool for individuals who want to adopt a long-term commitment to health and fitness. While it can potentially produce great effects for many people, it is critical to control expectations and recognize that it works best when combined with regularity and a healthy lifestyle. Mitolyn is designed for people who want to invest in their long-term health rather than take shortcuts. If you're weary of irritating weight loss plateaus and need a scientifically proven boost, Mitolyn could be the game changer you've been looking for. (LIMITED STOCK) Click Here to Buy Mitolyn at a Special Discounted Price Today!

23 Gifts From Asian-Owned Businesses That'll Please Everyone, Even That One Picky FriendBy LINDSEY BAHR Do you have a someone in your life who plays Vulture’s Cinematrix game every morning? Or maybe they have the kitchen television turned to Turner Classic Movies all day and make a point of organizing Oscar polls at work? Hate to break it to you: They might be a hard-to-please cinephile. But while you might not want to get into a winless debate over the “Juror No. 2” release or the merits of “Megalopolis” with said person, they don’t have to be hard to buy gifts for. The Associated Press has gathered up some of the best items out there to keep any movie lover stylish and informed. “Interstellar” 4K UHD While Christopher Nolan dreams up his next film, fans can tide themselves over by revisiting his modern classic “Interstellar,” which will be back in IMAX theaters on the weekend of Dec. 6, followed by the home release of a new collector’s edition on 4K Ultra HD and Blu-ray ($59.95). A third disc in the set, available Dec. 10, contains more than two hours of bonus content, like a never-before-seen storyboard sequence, and new interviews with Nolan, producer Emma Thomas and famous fans Peter Jackson and Denis Villeneuve . A biography of Elaine May Elaine May does not give interviews anymore. But thankfully that didn’t deter writer Carrie Courogen, who did a remarkable job stitching together the life of one of our culture’s most fascinating, and prickly, talents. “Miss May Does Not Exist” is full of delightful anecdotes about the sharp and satirical comedian who gained fame as one half of Nichols and May and went on to direct films like “The Heartbreak Kid” and “Mikey and Nicky.” Courogen writes about May’s successes, flops and her legendary scuffles with the Hollywood establishment. It’s a vital companion to Mark Harris’ biography of Mike Nichols . Macmillan. $30. A “Matrix” hoodie The Academy Museum of Motion Pictures has an exclusive new “Matrix” sweatshirt for sale in conjunction with its Cyberpunk exhibition. Brain Dead Studios designed and created several items, including the black hoodie ($140), a white rabbit tee ($54) and a pint glass ($18). An Academy Museum exhibition catalog If you can’t make it to Los Angeles to check out the “Color in Motion” exhibit for yourself, the Academy Museum also has a beautiful new companion book for sale ($55) charting the development of color technology in film and its impact. It includes photos from films like “The Red Shoes,” “Vertigo,” “2001: A Space Odyssey,” and images of rare prints from the silent era. The Academy Museum Store is having a sale (20% off everything) from Nov. 28 to Dec. 2. A status tote Related Articles Things To Do | US airports with worst weather delays during holiday season Things To Do | The right book can inspire the young readers in your life, from picture books to YA novels Things To Do | These holiday gifts change the game when building fires, printing photos, watching birds and more Things To Do | ‘Gladiator II’ review: Are you not moderately entertained? Things To Do | Beer pairings for your holiday feasts Want to look like a real film festival warrior, the kind who sees five movies a day, files a review and still manages to make the late-night karaoke party? You’re going to need the ultimate status tote from the independent streaming service MUBI . Simple, to-the-point and only for people in the know. $25. The Metrograph magazine Film magazines may be an endangered species, but print is not dead at The Metrograph . Manhattan’s coolest movie theater is starting a biannual print publication “for cinephiles and cultural connoisseurs alike.” The first issue’s cover art is by cinematographer Ed Lachman (“Carol”), and contributors include the likes of Daniel Clowes, Ari Aster, Steve Martin and Simon Rex. There’s also a conversation with Clint Eastwood. It’s currently available for pre-order and will be in bookstores Dec. 10 for $25 ($15 for Metrograph members). Director style This is not a book about filmmaking styles, camera angles and leadership choices. It’s literally about what directors wear. “How Directors Dress: On Set, in the Edit, and Down the Red Carpet” ($40) has over 200 archival photos of filmmakers in action: Spike Lee in his basketball caps, Sofia Coppola in her Charvet button-ups, Steven Spielberg’s denim on denim and many more. With a forward by the always elegant Joanna Hogg and writing from some of the top fashion journalists, it’s a beautiful look at how filmmakers really dress for work — and might even be a source of inspiration.

The past five years have seen various funds and managers come to the fore in the annual Raging Bull Awards, which recognise outstanding performance by asset managers offering unit trust funds to retail investors. While large established firms such as Ninety One (previously Investec Asset Management) and PSG featured strongly, smaller, so-called "boutique" managers stole the limelight in many instances. 2020 The 2020 ceremony, for performance to the end of 2019, saw Cape-Town-based boutique manager Mi-Plan clinch the South African Manager of the Year title ahead of Investec Asset Management. Mi-Plan director Anton Turpin said the awards gave smaller firms a platform to show off their investment skills: "It's an opportunity for smaller managers to reach investors and tell them about the rewards they can get through good stock selection, good asset allocation and good risk management." Kagiso (now Camissa) Asset Management, walked away with the most fund awards: two certificates and one trophy for straight... Martin Hesse

Michael Dell’s net worth (and how much he makes as CEO)

Israel-Hezbollah ceasefire offers a fragile peace some fear will not be enough