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chess online game RA Capital Management Announces Close of $1.4 Billion Acquisition of Aliada Therapeutics by AbbVie

MALVERN, Pa., Nov. 25, 2024 (GLOBE NEWSWIRE) -- Vishay Precision Group, Inc. (NYSE: VPG), a leader in precision measurement and sensing technologies, announced today that it will present at the following investor conferences in December 2024: For more information or to arrange meetings at either of these conferences, please contact: info@vpgsensors.com . About VPG Vishay Precision Group, Inc. (VPG) is a leader in precision measurement and sensing technologies. Our sensors, weighing solutions and measurement systems optimize and enhance our customers’ product performance across a broad array of markets to make our world safer, smarter, and more productive. To learn more, visit VPG at www.vpgsensors.com and follow us on LinkedIn . For Investors: Vishay Precision Group Steve Cantor, 781-222-3516 info@vpgsensors.com'That's Ridiculous': 'The View' Hosts Get Slapped with Reality About Biden, And They Didn't Take It Too Well

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Closing marks second significant acquisition from RA Capital's Raven incubator in 2024, and first acquisition of a company built by Raven from a technology platform in-licensed from a large pharmaceutical company BOSTON , Dec. 11, 2024 /PRNewswire/ -- RA Capital Management, LP (RA Capital), a multi-stage investment manager dedicated to evidence-based investing in public and private healthcare, life sciences, and planetary health companies, today announced that AbbVie has closed its $1.4 billion acquisition of RA Capital's portfolio company Aliada Therapeutics. Aliada's lead investigational asset is ALIA-1758, an anti-pyroglutamate amyloid beta (3pE-Aβ) antibody, which is in development for the treatment of Alzheimer's disease and is currently in a Phase 1 clinical trial. ALIA-1758 utilizes a novel blood-brain barrier-crossing technology that enhances delivery of targeted drugs into the central nervous system. Johnson & Johnson (through its venture capital arm, Johnson & Johnson Innovation – JJDC, Inc.), RA Capital, and Raven (RA Capital's healthcare incubator) co-founded Aliada and co-led the series seed financing in 2021 to advance the MODELTM platform created by Johnson & Johnson scientists that was licensed to Aliada at its inception. "Congratulations to the Aliada and AbbVie teams and our fellow investors on the close of this transaction," said Joshua Resnick , MD, Senior Managing Director at RA Capital Management and former board director at Aliada. "The acquisition of Aliada is the second significant acquisition of a Raven-grown company this year, joining Novartis' $1 billion upfront acquisition of radiopharmaceutical developer Mariana Oncology in May." "Delivering therapeutics across the blood-brain barrier with a low-volume, subcutaneous injection would be revolutionary for treating Alzheimer's disease and other neurological disorders, and has long been a dream in the field," said Laura Tadvalkar , PhD, Managing Director at RA Capital Management and former board chair at Aliada. "We look forward to following ALIA-1758's progress through the clinic, as AbbVie advances this important medicine for Alzheimer's disease patients." About Raven Raven is RA Capital Management's healthcare incubator. Raven's experienced team of scientists, operators, and innovators bring deep sector expertise, insight and executional capabilities across therapeutics, diagnostics, devices, and services. Raven builds companies: from originating and incubating new ideas to accelerating compelling innovations and rejuvenating promising assets. About RA Capital Founded in 2004, RA Capital Management is a multi-stage investment manager dedicated to evidence-based investing in public and private healthcare, life sciences, and planetary health companies. RA Capital creates and funds innovative companies, from private seed rounds to public follow-on financings, allowing management teams to drive value creation from inception through commercialization and beyond. RA Capital's knowledge engine is guided by our TechAtlas internal research division, and Raven, RA Capital's company creation team, offers entrepreneurs and innovators a collaborative and comprehensive platform to explore the novel and the re-imagined. RA Capital has more than 175 employees and over $10 billion in assets under management. The companies presented herein were selected to demonstrate a potential successful outcome of a company being incubated within our Raven incubator. They are not intended to represent a complete picture of RA Capital's portfolio, its exposures, risks or potential for positive or negative returns. Past performance is not indicative of future results. SOURCE RA Capital Management, LPFBI Director Christopher Wray announced on Wednesday that he will resign in January before President-elect Donald Trump takes office. "After weeks of careful thought, I've decided the right thing for the bureau is for me to serve until the end of the current administration in January and then step down," Wray told bureau employees in remarks released by the FBI. Trump, who is to be sworn in as president on January 20, has announced the nomination of staunch loyalist Kash Patel to replace Wray as the head of the top US law enforcement agency and he welcomed the FBI chief's resignation. Wray was named by Trump in 2017 to head the 38,000-strong Federal Bureau of Intelligence but the incoming president has since soured on his choice. Wray had three more years remaining in his 10-year term as FBI director but faced potentially being fired by Trump. "The resignation of Christopher Wray is a great day for America as it will end the Weaponization of what has become known as the United States Department of Injustice," Trump said in a post on Truth Social. "Under the leadership of Christopher Wray, the FBI illegally raided my home, without cause, worked diligently on illegally impeaching and indicting me, and has done everything else to interfere with the success and future of America," Trump said. The FBI raided Trump's Mar-a-Lago home in August 2022 to recover top secret documents taken without authorization from the White House. Trump was indicted for mishandling classified documents and obstruction of justice but the case was dismissed by a Trump-appointed judge. Wray, in his remarks to the FBI workforce, said stepping down "is the best way to avoid dragging the bureau deeper into the fray, while reinforcing the values and principles that are so important to how we do our work." "In terms of how we do the work, we've got to maintain our independence and objectivity -- staying above partisanship and politics," he said. "That's what the American people expect of us and that's what they deserve." Patel, a former Trump advisor and Pentagon official, has been critical of the FBI and is known for his controversial views. A fierce defender of the incoming president, Patel supports the Republican hardliner notion of an anti-Trump "deep state" of allegedly biased government bureaucrats working to stifle Trump from behind the scenes, even having written a book on the subject. A son of Indian immigrants, Patel served in several high-level posts during Trump's first term including as a national security advisor and as chief of staff to the acting defense secretary. Trump, in his Truth Social post, accused law enforcement officials of using "their vast powers to threaten and destroy many innocent Americans, some of which will never be able to recover from what has been done to them." "Kash Patel is the most qualified Nominee to lead the FBI in the Agency's History, and is committed to helping ensure that Law, Order, and Justice will be brought back to our Country again, and soon," he said. "I look forward to Kash Patel's confirmation, so that the process of Making the FBI Great Again can begin." Attorney General Merrick Garland praised Wray's "principled leadership" of the FBI, saying he had served "honorably and with integrity." "The director of the FBI is responsible for protecting the independence of the FBI from inappropriate influence in its criminal investigations," Garland said in a statement. "That independence is central to preserving the rule of law and to protecting the freedoms we as Americans hold dear." cl/dw

NoneOTTAWA — The federal Liberal government isn’t yet naming a new point person on Jasper after Alberta MP Randy Boissonnault’s departure from cabinet, but says that rebuilding the fire-ravaged Alberta town remains a top priority. “Multiple members of our caucus are engaged on the file,” a senior government official told the National Post. “We’ll continue to coordinate recovery efforts with provincial and local officials.” Boissonnault, the only Albertan in Trudeau’s cabinet until Wednesday, was named ministerial lead for Jasper in October. He said at the time that this was an important role for him to take on as the province’s lone federal minister. “As the Alberta minister, it’s really important that I’m able to do that work with a number of ministers at the provincial level so we can get the work done,” Boissonnault told reporters in Ottawa. Boissonnault was put in charge of a cabinet-level working group on Jasper, subsequently overseeing the distribution of more than $20 million of federal aid to the municipality. Jasper Mayor Richard Ireland said on Wednesday he was sad to see Boissonnault step away from the role. “We are disappointed to be losing Minister Boissonnault as federal ministerial lead for Jasper recovery,” wrote Ireland in an email. “He immersed himself in our ongoing challenges and was an engaged, active, and an effective advocate on our behalf.” The Opposition Conservatives weren’t quite as concerned about the void created by Boissonnault’s departure. “The Trudeau government was repeatedly warned but allowed Jasper to go up in flames after years of ignoring obvious severe fire risks. After nearly a decade of neglect, it doesn’t matter which Liberal is selected to replace Trudeau’s fake advisor,” said Conservative emergency affairs critic Dane Lloyd on Wednesday. Alberta Municipal Affairs Minister Ric McIver, the province’s lead on Jasper, declined to comment on Boissonnaut’s departure. The Town of Jasper lost a third of its structures in July after a wildfire that started in nearby federal parkland jumped the Columbia river, forcing some 25,000 to flee the area. The disaster came after experts warned for years about the possibility of a “catastrophic blaze” in the area, raising several questions about the federal government’s forest management practices, including its failure to remove thousands of pine beetle ravaged dead trees from the area. The House of Commons set up a committee to investigate the causes of the blaze in September. Boissonnault’s departure from the cabinet working group on Jasper leaves six remaining members, including Environment Minister Steven Guilbeault, Housing Minister Sean Fraser and Minister for Emergency Preparedness Harjit Sajjan. Guilbeault is also the minister responsible for Parks Canada. Liberal officials wouldn’t say what role Boissonnault will have on the Jasper file as a rank-and-file member of the party’s caucus. The prime minister said in a Wednesday statement that veterans affairs minister Ginette Petitpas Taylor would temporarily take on Boissonnault’s responsibilities as employment minister and minister responsible for official languages. Petitpas Taylor’s office told the National Post on Thursday that she won’t be taking on the role of ministerial lead for Jasper. National Post rmohamed@postmedia.com Get more deep-dive National Post political coverage and analysis in your inbox with the Political Hack newsletter, where Ottawa bureau chief Stuart Thomson and political analyst Tasha Kheiriddin get at what’s really going on behind the scenes on Parliament Hill every Wednesday and Friday, exclusively for subscribers. Sign up here . Our website is the place for the latest breaking news, exclusive scoops, longreads and provocative commentary. Please bookmark nationalpost.com and sign up for our politics newsletter, First Reading, here .

Our community members are treated to special offers, promotions and adverts from us and our partners. You can check out at any time. More info Tulisa is said to have vanished from the Australian hotel she was booked into after she was booted off I’m a Celebrity... Get Me Out of Here!. The 36-year-old left the camp on Tuesday, being the third contestant to be eliminated from the ITV show , with rumours swirling after she failed to appear for a post-show interview. Fans speculated something may be wrong due to her no-show and the fact she wiped all the I'm A Celebrity content from her Instagram, which was being run by a pal while she was on the show. The Mirror reports that, after crossing the red bridge, the musician joined cast and crew in a JW Marriott Hotel nearby - but disappeared from the luxury lodgings. An insider told The Sun : "Tulisa and the two friends who came to Australia with her disappeared after she came out. No one saw her in the hotel and she wasn’t talking to anyone. "Her mates were talking among themselves and were worried as no one could pin her down. They were chatting back and forth in their group chats and no one could raise her. It was total radio silence." A second source also came forwards, adding: "Not having Tulisa at the hotel with the other stars has been odd, and people don’t know whether or not she’ll be back to film the reunion. "Naturally everyone just wants her to be all right and ITV and her campmates are being supportive." Tulisa briefly touched on her unexpected actions after leaving the ITV show, and admitted on Instagram that she was taking a moment for herself. Get the latest news sent straight to your messages by joining our WhatsApp community today. You'll receive daily updates on breaking news as well as the top headlines across Scotland. No one will be able to see who is signed up and no one can send messages except the Daily Record team. All you have to do is click here if you're on mobile , select 'Join Community' and you're in! If you're on a desktop, simply scan the QR code above with your phone and click 'Join Community'. We also treat our community members to special offers, promotions, and adverts from us and our partners. If you don’t like our community, you can check out any time you like. To leave our community click on the name at the top of your screen and choose 'exit group'. If you’re curious, you can read our Privacy Notice. In a short video, the 36-year-old explained: "I can get overwhelmed quite easily and started to feel overwhelmed. I realised I needed to take time for myself, and to chill, it's all a little bit much at the moment.” The former N-Dubz singer then explained why she had deleted her social posts and said her page - which was run by pals while she was in camp - is not how she would have done things. She said: "I'm just going to archive all my stuff to do with the jungle and then, when the time is right and I've had time to process, I'm going to make my own reels of my best bits that I really like," she said. "Because remember, I haven't been doing my Instagrams . The way it's being posted and all the random stuff is not how I would do my Insta - I would have one or two really good reels relating to the jungle and bringing my time together there." However, it has now been claimed that Tulisa - real name Tulisa Contostavlos - had a massive row with her friend, Michelle McKenna, who came to greet her in the jungle once Tulisa was evicted. According to a source , Tulisa feels as though her friend 'took liberties' by flying to Australia to greet her. Speaking to Mail Online , they claimed: "They were only in Australia because of Tulisa. "It felt like they were revelling in the situation and taking liberties on her kindness. Michelle and Daniel were there, on a trip funded by ITV and only because of Tulisa. They were there because of her and she trusted them with her social media. "When she got out of the jungle and saw what had been put on there, she was upset and it prompted a huge row. You can't help but think that seeing her friends living it up like that while she was roughing it in the jungle must have really annoyed her." Don't miss the latest news from around Scotland and beyond. Sign up to our daily newsletter .SANTA CLARA — When Isaac Guerendo trots onto the field with the first team Sunday at Levi’s Stadium, he will equal the same number of starts he had in five years of college football. Hard to believe, but Guerendo started exactly one time, and it came in his final college game at Louisville. Against USC in the Holiday Bowl, Guerendo carried 23 times for 161 yards and three touchdowns and added five receptions in a 42-28 loss. In 40 other games at Wisconsin and Louisville, Guerendo played in a shared backfield –something he’s done with the 49ers this season behind Jordan Mason and Christian McCaffrey . With McCaffrey on injured reserve with a PCL strain and Mason to follow soon with a high ankle sprain, Guerendo should get his biggest workload since his last college game. “I’m excited, but really it’s whatever it takes to win,” Guerendo said Wednesday as the 49ers (5-7) began preparations to host the Bears (4-8). “Whatever the plan looks like is what we’ll bring.” Guerendo will be backed up by Patrick Taylor Jr., who was on the roster earlier this season when McCaffrey was dealing with bilateral Achilles tendinitis, then re-signed to the practice squad. Taylor was promoted Tuesday, and the 49ers also made a waiver claim on former Jets running back Israel Abanikanda. “I think he’s ready to go,” 49ers coach Kyle Shanahan said. “He had some ups and downs but got better through everything. I think he’s ready for this.” Guerendo, 6-foot and 219 pounds, has 42 carries for 246 yards and two touchdowns, averaging a gaudy 5.9 yards per carry. His 15-yard run in the third quarter was the 49ers’ lone touchdown in a 35-10 loss to the Buffalo Bills. The 49ers traded up to get Guerendo in the fourth round, only to see him sidelined with a hamstring strain in his first training camp practice. A speedy wide receiver at Avon High School in Indiana who also ran track and played basketball, Guerendo carried 10 times for 99 yards with a long run of 76 against Seattle and 14 times for 85 yards against Dallas. At Wisconsin, Guerendo played behind Jonathan Taylor, now a star running back for the Indianapolis Colts. He split time as a graduate student at Louisville with Jawhar Jordan, who rushed for 1,128 yards while Guerendo had 810 yards on 132 carries and a 6.1-yard average. The good news is Guerendo’s body hasn’t taken on the normal amount of abuse for a running back. And Guerendo feels he’s up to the challenge after playing 12 games with old-school running backs coach Bobby Turner. “I always give credit to Coach T for preparing everybody like they’re going to be the starter, so that when moments do come, you’re ready for it,” Guerendo said. McCaffrey appeared to have finally gotten untracked against the Bills, gaining 53 yards on seven carries before getting tripped up on a 19-yard burst in the second quarter. But the tackle injured his knee, Mason injured his ankle, and Guerendo became the lead runner for a team that is sixth in the NFL in rushing. Over time, Guerendo has become accustomed to the speed of the NFL game. “I think it takes guys some time,” Shanahan said. “You start to get a feel for it, if you’ve got the right stuff, you get more reps and the more you adjust to it. How hard you’ve got to hit stuff, how quick those holes close, how you have to hit it full speed and can’t hesitate. We’ve seen that stuff get better in practice and we’ve seen it carry over into games.” McCaffrey, meanwhile, took to social media in the form of a lengthy Instagram post to explain how he was feeling after his latest injury. He wrote of his love for football, how humbling it is and his desire to return. “This wasn’t my year, and sometimes when it rains, it pours,” McCaffrey wrote. “You can feel sorry for yourself and listen to the birds, or you can hold the line. I’m grateful for the support of everyone in my corner and promise I’ll work smarter and harder to come back better from this.” For those who dream big, Shanahan said with a six-week time frame, McCaffrey could conceivably return if the 49ers reach the postseason. THE INJURY LIST Those who didn’t practice Wednesday included edge rusher Nick Bosa (hips, obliques), left tackle Trent Williams (ankle), left guard Aaron Banks (concussion), Mason (ankle) and linebacker Demetrius Flannigan-Fowles (ankle). Cornerback Deommodore Lenoir (knee), linebacker Dre Greenlaw (Achilles) and safety Talanoa Hufanga (wrist) were limited. Defensive tackle Jordan Elliott has cleared concussion protocol after missing the Buffalo game. Hufanga joined Greenlaw as practicing during a 21-day window. Shanahan said it’s more likely Greenlaw would be activated before a Thursday night game against the Los Angeles Rams on Dec. 12 than against Chicago. HUFANGA AND THE CLUB After recovering from an ACL tear last season, Hufanga has played in just two games this season. First, he was felled by an ankle injury, and then a wrist injury that needed surgery. When activated, he’ll play with a protective club on his right hand. “I was still dealing with the ankle. I was about to get it re-wrapped and for some reason my hand wouldn’t open,” Hufanga said. Hufanga said he’ll try to use the protective device as a benefit rather than a detriment. “I had a good friend back in the day who played with a club who had three picks in one game, so you never know,” Hufanga said. MOORE FARES WELL Left tackle Jaylon Moore acquitted himself well for the second straight game in starting in place of Williams. “It was OK, but you can always get better and that’s what I’m focusing on — the things I can get better at,” Moore said. Tight end George Kittle noted last week that Moore was at left tackle all through training camp during Williams’ holdout, so it’s not like he hasn’t been with the first team. “It definitely did help, especially being comfortable with the group,” Moore said. “The quarterback’s cadence, the guy you’re next to, all the small stuff comes into play.”

Courtland Sutton's surge is helping rookie Bo Nix and the Denver Broncos make a playoff push

ICPC chairman to judges: Prosecution critical in fight against corruptionWASHINGTON — The Supreme Court sounded hesitant Wednesday to second-guess Tennessee lawmakers who banned gender-affirming care for minors, as justices heard warnings that upholding the law could lead to other state or national restrictions on transgender Americans. During more than two hours of oral argument, members of the court’s conservative wing repeatedly expressed reticence to step into policy disputes over access to transgender care for minors, raising questions about the science behind the care and the fallout for other transgender issues such as access to women’s sports. The state law bans puberty blockers, hormone therapy and surgery for minors for the purpose of medically transitioning their gender. Challengers have asked the justices to rule that the law unconstitutionally discriminates on the basis of sex because it prohibits access to that care when it is for the purpose of gender transition. Justice Brett M. Kavanaugh said there were “forceful policy arguments” on both sides of the Tennessee law, including how the ban harmed transgender children but also prevented a small number of children from being harmed by the treatments. Kavanaugh said that disputes about the medical efficacy of treatments “strikes me as a pretty yellow light or red light” for the court to intervene. “So it seems to me that we look to the Constitution, and the Constitution doesn’t take sides on how to resolve that medical and policy debate,” Kavanaugh said. Chief Justice John G. Roberts Jr. repeatedly brought up disputes about the medical science behind gender-affirming care and wondered whether it would be better to “leave those determinations to legislative bodies rather than try to determine them ourselves.” Roberts later said it was “very troubling” that the court could step into an area where they are “bereft of expertise” around complicated questions of medical effectiveness. And Justice Samuel A. Alito Jr. repeatedly brought up a literature review in the United Kingdom that questioned the efficacy of gender-affirming care and recent decisions by medical bodies in the U.K. and Sweden to restrict access. Families and doctors of transgender children, as well as the Biden administration, challenged the law, arguing it violates the 14th Amendment’s Equal Protection Clause because it prohibits access to those medicines based on gender transition but not for other conditions such as precocious puberty. The challengers and major medical organizations have maintained that the treatments are effective, including by reducing depression and suicidal ideation among transgender children. About two dozen states have similar laws banning access to gender-affirming care for minors, and the case comes to the court as Republicans nationwide, including in Congress, have said they intend to impose more restrictions on the care. Solicitor General Elizabeth Prelogar told the justices Wednesday that upholding the law, which explicitly states its goal for minors to “appreciate their sex,” allows transgender youth in the state to suffer. “It doesn’t matter what parents decide is best for their children. It doesn’t matter what patients would choose for themselves. And it doesn’t matter if doctors believe this treatment is essential for individual patients,” Prelogar said. The Tennessee law “categorically bans treatment when and only when it’s inconsistent with the patient’s birth sex.” Prelogar pointed out that the treatments are restricted but still available in the U.K. and Sweden rather than the ban that Tennessee imposed. Prelogar and Chase Strangio, attorney for the families challenging the law, both pointed to West Virginia’s law as an example, because the state has restricted gender-affirming care rather than banning access and has yet to face legal challenge. Prelogar said the justices also could send the case back to the lower court with instructions to make sure the state better justifies with evidence its efforts to restrict the treatments. J. Matthew Rice, arguing for Tennessee, claimed the treatments were “risky and unproven” and said the law turned on the medical purposes of taking hormones or puberty blockers, rather than a sex classification. Rice also compared gender-affirming care to assisted suicide, lobotomies and eugenics that states had a right to regulate. “The Equal Protection Clause does not require the states to blind themselves to medical reality or to treat unlike things the same, and it does not constitutionalize one side’s view of a disputed medical question,” Rice said. Rice argued that the challengers could not eliminate risks from the procedures or the possibility that patients could detransition later, at which point Justice Sonia Sotomayor interrupted to say, “Every medical treatment has risks.” Sotomayor raised the concern that the same logic could apply to medical care for adults, and that upholding Tennessee’s law would be “licensing states to deprive full adults of the choice of which sex to adopt.” Sotomayor also downplayed the ability of the democratic process to protect such a small minority of the population if the court doesn’t intervene. “It didn’t protect women for centuries,” she said. President-elect Donald Trump’s campaign included explicit promises to target transgender care, and members of Congress have said they intend to legislate on the issue when they come into power with a trifecta in January. Justice Ketanji Brown Jackson said she found similarities between Tennessee’s argument and the ones made by Virginia to try and uphold anti-miscegenation laws in Loving v. Virginia. Jackson pointed out that Virginia pointed to “disputed” medical science about race-mixing to try and justify the law. “I wonder if Virginia could have gotten away with what they did here by making a classification argument,” Jackson said. Justice Elena Kagan rejected Tennessee’s effort to categorize the use of hormones and puberty blockers as different medical purposes. “The whole thing is imbued with sex,” Kagan said. “It is a dodge to say it is based on a medical purpose.” On Wednesday, Rep. Mark E. Green, R-Tenn., praised the state’s stance in a post on social media. “Tennessee is leading the way and standing up for our children. Minors must be protected from these harmful and irreversible medical experiments,” Green posted. Similarly, Rep. Nancy Mace, R-S.C., posted on X calling gender-affirming care “child abuse.” Mace has previously said she would back legislation to bar access for transgender individuals to the bathrooms of the gender they identify as. ©2024 CQ-Roll Call, Inc., All Rights Reserved. Visit cqrollcall.com. Distributed by Tribune Content Agency, LLC.

The largest artificial intelligence data center ever built by Facebook’s parent company Meta is coming to northeast Louisiana , the company said Wednesday, bringing hopes that the $10 billion facility will transform an economically neglected corner of the state. Republican Gov. Jeff Landry called it “game-changing” for his state's expanding tech sector, yet some environmental groups have raised concerns over the amount of energy it would use — and whether it could lead to higher energy bills in the future. Meanwhile, Elon Musk 's AI startup, xAI, is expanding its existing supercomputer project in Memphis, Tennessee, the city's chamber of commerce said Wednesday. The chamber also said that Nvidia, Dell, and Supermicro Computer will be “establishing operations in Memphis,” without offering further details. Louisiana is among a growing number of states seeking to lure big tech firms in need of energy-intensive data centers with tax credits and other incentives. The U.S. Commerce Department found that there aren’t enough data centers in the U.S. to meet the rising AI-fueled demand, which is projected to grow by 9% each year through 2030, citing industry reports. Meta anticipates its Louisiana data center will create 500 operational jobs and 5,000 temporary construction jobs, said Kevin Janda, director of data center strategy. At 4 million square feet (370,000 square meters), it will be the company's largest AI data center to date, he added. “We want to make sure we are having a positive impact on the local level,” Janda said. Congressional leaders and local representatives from across the political spectrum heralded the Meta facility as a boon for Richland parish, a rural part of Louisiana with a population of 20,000 historically reliant on agriculture. About one in four residents are considered to live in poverty and the parish has an employment rate below 50%, according to the U.S. census data. Meta plans to invest $200 million into road and water infrastructure improvements for the parish to offset its water usage. The facility is expected to be completed in 2030. Entergy, one of the nation's largest utilities providers, is fast-tracking plans to build three natural gas power plants in Louisiana capable of generating 2,262 megawatts for Meta's data center over a 15 year period — nearly one-tenth of Entergy's existing energy capacity across four states. The Louisiana Public Service Commission is weighing Entergy's proposal as some environmental groups have opposed locking the state into more fossil fuel-based energy infrastructure. Meta said it plans to help bring 1,500 megawatts of renewable energy onto the grid in the future. Louisiana residents may ultimately end up with rate increases to pay off the cost of operating these natural gas power plants when Meta's contract with Entergy expires, said Jessica Hendricks, state policy director for the Alliance for Affordable Energy, a Louisiana-based nonprofit advocating for energy consumers. “There’s no reason why residential customers in Louisiana need to pay for a power plant for energy that they’re not going to use," Hendricks said. "And we want to make sure that there’s safeguards in place.” Public service commissioner Foster Campbell, who represents northeast Louisiana, said he does not believe the data center will increase rates for Louisianians and views it as vital for his region. “It’s going in one of the most needed places in Louisiana and maybe one of the most needed places in the United States of America,” Foster said. “I’m for it 100%.” Environmental groups have also warned of the pollution generated from Musk's AI data center in Memphis. The Southern Environmental Law Center, among others, says the supercomputer could strain the power grid, prompting attention from the Environmental Protection Agency. Eighteen gas turbines currently running at xAI’s south Memphis facility are significant sources of ground-level ozone, better known as smog, the group said. Patrick Anderson, an attorney at the law center, said xAI has operated with “a stunning lack of transparency” in developing its South Memphis facility, which is located near predominantly Black neighborhoods that have long dealt with pollution and health risks from factories and other industrial sites. “Memphians deserve to know how xAI will affect them,” he said, “and should have a seat at the table when these decisions are being made.” _____ Sainz reported from Memphis, Tennessee. Associated Press writer Matt O’Brien in Providence, Rhode Island, contributed to this report. _____ Brook is a corps member for The Associated Press/Report for America Statehouse News Initiative. Report for America is a nonprofit national service program that places journalists in local newsrooms to report on undercovered issues. Follow Brook on the social platform X: @jack_brook96None

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