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WALTHAM, Mass. , Dec. 3, 2024 /PRNewswire/ -- Syndax Pharmaceuticals (Nasdaq: SNDX), a commercial-stage biopharmaceutical company developing an innovative pipeline of cancer therapies, today announced that on December 1, 2024 the Company granted inducement awards to purchase up to 23,900 shares of common stock to two new employees under the Company's 2023 Inducement Plan. The stock options will vest over four years, with 25% of the underlying shares vesting on the one-year anniversary of the vesting commencement date and 1/48th of the underlying shares vesting monthly thereafter over 36 months, subject to the employee's continued service relationship with Syndax through the applicable vesting dates. About Syndax Syndax Pharmaceuticals is a commercial-stage biopharmaceutical company developing an innovative pipeline of cancer therapies. Highlights of the Company's pipeline include Revuforj ® (revumenib), an FDA-approved menin inhibitor, and NiktimvoTM (axatilimab-csfr), an FDA-approved monoclonal antibody that blocks the colony stimulating factor 1 (CSF-1) receptor. Fueled by our commitment to reimagining cancer care, Syndax is working to unlock the full potential of its pipeline and is conducting several clinical trials across the continuum of treatment. For more information, please visit www.syndax.com or follow the Company on X (formerly Twitter) and LinkedIn . Syndax Contact Sharon Klahre Syndax Pharmaceuticals, Inc. sklahre@syndax.com Tel 781.684.9827 View original content: https://www.prnewswire.com/news-releases/syndax-pharmaceuticals-reports-inducement-grants-under-nasdaq-listing-rule-5635c4-302316942.html SOURCE Syndax Pharmaceuticals, Inc.Dr Charlotte Proudman, who specialises in family law, had faced a Bar Standards Board (BSB) disciplinary tribunal over a 14-part Twitter thread criticising a judge’s ruling over a domestic abuse case, saying it echoed a “boys’ club”. However, the five charges against the 36-year-old were dropped on Thursday. In an interview with The Times, Dr Proudman described the position of Mark Neale, the board’s director-general, as “untenable” and said its chairwoman, Kathryn Stone, should also stand down. “They need a change, not just in those two individuals, though, because, of course, it seeps down to the rest of the organisation,” she said. She told the paper she “genuinely” wanted to work with the Bar Standards Board in helping them to understand how misogyny and sexism have impacted women at the bar. However, she said that “under the current leadership, it’s just not going to be possible”. The charges alleged Dr Proudman had “failed to act with integrity” in posting the tweets, that they amounted to professional misconduct, were “misleading” and “inaccurately reflected the findings of the judge” in the case. The women’s rights campaigner was also accused of behaving in a way “which was likely to diminish the trust and confidence which the public placed in her and in the profession”, and that she “knowingly or recklessly misled or attempted to mislead the public” by making the posts. But panel chairman Nicholas Ainley found her tweets are protected under Article 10 of the Human Rights Act 1998 and the European Convention on Human Rights, which protects the right of freedom of expression. He said her tweets did not “gravely damage” the judiciary, which would “put them outside” of Article 10 protection, even if they “might not have been pleasant for any judge to read” or even “hurtful”. “We take the view that the judiciary of England and Wales is far more robust than that,” he said. The panel also concluded that some of the tweets were only inaccurate “to a minor degree” and not to the extent necessary for a charge of a lack of integrity. Speaking after the hearing, Dr Proudman told the PA news agency: “This ruling is a victory for women’s rights and a right to freedom of speech. “The prosecution against me brought by my regulatory body, the Bar Standards Board, should never have happened and I said that from day one. “I criticised a domestic abuse judgment. Everyone should have the right to do that, whether you’re a barrister or not. Our justice system, which I strongly believe in, is robust enough to withstand criticism from me.” She believes her tweets help “foster confidence” in the justice system, adding: “Only that way can we go about building change and a better treatment for all victims, women and children and men who are affected by domestic abuse.” Explaining that the BSB appears to have spent almost £40,000 “of barristers’ money” on instructing counsel in her case, she added: “I think it’s shameful that they’re using our money to pay for, in my view, malicious, vexatious prosecutions which I have no doubt was a personal attack against me as a woman and as a feminist, as an outspoken critic and advocate for women’s rights.” Dr Proudman called for “systemic change” within the board. “They don’t understand gender, they don’t understand diversity, I don’t think they’ve ever heard of the concept misogyny and certainly not institutional misogyny,” she said. “Until they recognise the deeply rooted, entrenched issue of bullying, harassment, sexism at the bar, for which I have suffered relentlessly... and own up to it I don’t think we’re going to see any change and I have no confidence in them.” She told of how male barristers have called her insulting names on social media and made derogatory comments about her. In the posts on April 6 2022, Dr Proudman referenced a case in which her client alleged she had been subjected to coercive and controlling behaviour by her husband, a part-time judge, meaning she had been “unable to freely enter” the couple’s “post-nuptial” financial agreement. Commenting on the ruling by Family Court judge Sir Jonathan Cohen, Dr Proudman wrote: “I represented Amanda Traharne. “She said she was coerced into signing a post-nuptial agreement by her husband (who is a part-time judge). I lost the case. “I do not accept the Judge’s reasoning. I will never accept the minimisation of domestic abuse.” She continued: “Demeaning the significance of domestic abuse has the affect of silencing victims and rendering perpetrators invisible. “This judgement has echoes of (t)he ‘boys club’ which still exists among men in powerful positions.” In the thread, Dr Proudman wrote that the judge had described the relationship of the couple as “tempestuous”, which she argued was a “trivialisation” of domestic abuse. “Tempestuous? Lose his temper? Isn’t this the trivialisation of domestic abuse & gendered language. This is not normal married life,” she wrote.
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In the bustling world of cryptocurrencies, Solana and Avalanche are making waves with their notable advancements in scalability and DeFi capabilities. Solana, with its rebound to $201 thanks to recent network upgrades and growing institutional interest, is poised to potentially hit $250. On the other hand, Avalanche is enhancing its ecosystem with subnets, further cementing its role as a frontrunner in blockchain customization and DeFi integration. Yet, it’s Web3Bay that’s truly disrupting the status quo, directly addressing the inefficiencies in e-commerce by removing expensive middlemen. With a presale price of just $0.003 and a projected 6430% ROI, Web3Bay is shaping up to be much more than just another digital token—it’s positioning itself as a revolutionary force in online shopping. Web3Bay Tackles Major eCommerce Issues; It’s Time to Consider 3BAY Web3Bay is confronting a significant pain point in eCommerce: the high cost of transactions. Standard online marketplaces depend on intermediaries such as payment processors and data brokers, who typically tack on fees of 2-5%. These extra costs are passed down to shoppers, making online purchases pricier than necessary. By leveraging blockchain technology, Web3Bay cuts out these middlemen, implementing smart contracts that both automate and secure transactions. This change leads to drastically lower fees and improved efficiency, presenting a win-win for consumers and merchants alike. For early backers, the financial upside is substantial. The initial presale price for 3BAY tokens is $0.003, with a planned incremental price rise of 15% across 28 stages, ultimately aiming for a price of $0.1959 per token. This strategy sets the stage for a potential 6430% ROI for early investors. More than just cost reductions, Web3Bay is redefining the eCommerce landscape by offering a decentralized, transparent, and efficient shopping experience, steering clear of the hidden charges and cumbersome processes typical of conventional platforms. Solana Bounces Back with Key Network Enhancements & Rising Institutional Support Solana is witnessing a robust rebound, driven by upgrades aimed at boosting scalability and cutting down on transaction costs, which have piqued the interest of various investment firms. Currently priced at $201, these enhancements, coupled with an influx of institutional support, have bolstered its position as a preferred platform for DeFi and NFT projects. Should Solana push past the $220 mark, we could see it escalate to $250 soon. However, any faltering in momentum could pull it back down to $180. Looking ahead, Solana’s trajectory could reach as high as $400 by 2025, thanks to its scalable infrastructure and growing presence in the Web3 ecosystem. Avalanche Expands with Strategic Subnet Deployments & DeFi Commitments Avalanche is broadening its reach by integrating subnets that enable customized blockchain solutions within its framework. This adaptability is attracting a slew of projects, especially from the DeFi space, in search of scalable and robust platforms. Analysts are optimistic that if Avalanche maintains its growth path, it could ascend to $50. Conversely, a slip below $30 could see it testing the $25 support level. With an eye on the future, expectations for Avalanche hover around $100 by 2025, driven by an upsurge in adoption and the popularity of its decentralized applications and strategic partnerships. Key Insights While Solana’s scalability and Avalanche’s adaptable subnets illustrate the broadening horizons of blockchain technology, Web3Bay is advancing this innovation by solving real-world eCommerce challenges. By reducing fees and boosting transaction transparency, Web3Bay not only empowers consumers but also offers unmatched ROI possibilities. The ongoing presale presents a golden opportunity for early investors and underscores Web3Bay’s potential as a longstanding leader in Web3 commerce. As the cryptocurrency landscape evolves, Web3Bay emerges not merely as a passing trend but as a sustainable investment that seamlessly links blockchain technology with practical, real-world applications. Join Web3Bay Presale Now: Presale: https://web3bay.io/buy Website: https://web3bay.io/ Twitter: https://x.com/web3bayofficial Instagram: https://www.instagram.com/web3bayofficial/
There are more NBA Cup games taking place on Friday, Nov. 22 including a matchup with the Boston Celtics going against the Washington Wizards at Capital One Arena in Washington D.C. The game is scheduled to start at 7 p.m. EST and will be broadcast on NBC Sports Boston . Fans looking to watch this NBA game can do so for free by using FuboTV and DirecTV Stream, which both offer a free trial or with SlingTV, which doesn’t offer a free trial but has promotional offers available . The Celtics are 12-3 after handing the Cleveland Cavaliers their first loss of the season. That win over the Cavaliers was also Boston’s first win in the NBA Cup to move the Celtics to 1-1. The Wizards lost their lone NBA Cup game so far and are 2-11 overall. Washington has lost nine straight games and is yet too win in November. Who: Boston Celtics vs. Washington Wizards When: Friday, Nov. 22 at 7 p.m. EST Where: Capital one Arena in Washington D.C. Stream: FuboTV (free trial) ; Sling ; DirecTV Stream (free trial) Betting: Check out our MA sports betting guide , where you can learn basic terminology, definitions and how to read odds for those interested in learning how to bet in Massachusetts. More College Football What is FuboTV? FuboTV is an internet television service that offers more than 200 channels across sports and entertainment including Paramount+ with SHOWTIME . From the UEFA Champions League to the WNBA to international tournaments ranging across sports, there’s plenty of options available on FuboTV, which offers a free trial, and $20 off the first month for new costumers. What is DirecTV Stream? DirecTV Stream offers practically everything DirecTV provides, except for a remote and a streaming device to connect to your television. Sign up now and get three free months of premium channels including MAX , Paramount+ with SHOWTIME and Starz. What is SlingTV? SlingTV offers a variety of live programing ranging from news and sports and starting as low as $20 a month for your first month. Subscribers also get a month of DVR Plus free if they sign up now. Choose from a variety of sports packages without long-term contracts and with easy cancelation. RELATED CONTENT: Analysis: Some NBA teams know it’s time to shake out of early-season slides — or else By TIM REYNOLDS AP Basketball Writer MIAMI (AP) — Postgame interviews in the NBA typically start about 10 minutes after the final buzzer. Coaches usually speak first, followed by a few players. When a team wins, most people are in a great mood. When a team loses, not so much. That’s the normal routine. Things are not normal for Philadelphia right now. Philadelphia lost in Miami on Monday night, the 76ers wasting an early 19-point lead and falling 106-89. The game ended at 9:51 p.m. It took more than an hour for coach Nick Nurse to emerge for his postgame media session. The reason — a team meeting, because the 76ers had a lot to talk about after falling to 2-11 on the season. “Sorry for the delay,” Nurse said to the half-dozen or so reporters who waited out his arrival. He took questions like normal, then the locker room opened and a few players talked as well. There’s a lot of the season left. The first quarter of the 82-game marathon isn’t even over. It’s not time to start panicking. But some teams, quite frankly, know it’s time for things to get better — Philly atop that list. Since the NBA went to the current 16-team playoff format in 1984, there have been only four teams with losing records after 15 games that made it to the NBA Finals: San Antonio in 1998-99, Detroit in 2004-05, Boston in 2021-22 and Miami in 2022-23. They were all 7-8. That’s bad news for Milwaukee, Philadelphia and Miami — three teams that just haven’t hit anything close to their best stride yet. Injuries are a huge part of that; Khris Middleton hasn’t played yet for Milwaukee, Joel Embiid played Monday night for only the third time this season for the 76ers, and the Heat got Jimmy Butler back after more than a week Monday but were without Terry Rozier and Jaime Jaquez Jr. But the Heat are 6-7, the Bucks are 5-9 and 76ers are 2-11. And that’s not anywhere near what those clubs expected coming into the year, injuries or no. “There’s urgency there, for sure,” Heat coach Erik Spoelstra said. “If you look at in both conferences, there’s urgency throughout the conferences. And I think there’s parity. It brings out great competition. It brings out all these different emotions. You win a game, you feel like everything is great. You lose a game, you feel like the world is coming down. That’s what competition does, particularly when you’re jostling so competitively in the standings where there’s a lot of teams bunched up.” Philadelphia hasn’t scored 100 points in three of its last four games, hasn’t even reached 90 points in either of its last two games. And here’s a weird stat: the 76ers are 2-0 in overtime games this season, 0-11 in games that end after 48 minutes. “Listen, it’s obviously difficult, right? Don’t like the losing, that’s for sure,” Nurse said. “I mean, it doesn’t matter. The games are coming and we’ve got to figure some things out. We’ve got to play better. Got to get our guys on the floor. There’s a lot of things going on. But we’ve got to go out and play and somehow sustain. A lot of these games, there’s lots of very good moments for long, long stretches.” Cleveland and Boston have obviously separated themselves atop the Eastern Conference; the 15-0 Cavaliers visit the 11-3 Celtics in an NBA Cup game on Tuesday night. From there, the rest of the East — from Orlando at 9-6 to Philly in a group at 2-11 — are separated by just six games, with about a million games left to play. Nobody is out of it, certainly not a 76ers team that has Embiid, Tyrese Maxey, Paul George and an NBA champion point guard in Kyle Lowry. “I mean, 2-11 is pretty bad, of course,” Philly’s Jared McCain said. “But it’s still the beginning of the season. Least minutes played as a team together, so I say it all the time: Give us grace. We’ve got to get better.” To be fair, there was nothing that seemed to be shattered in the 76ers' locker room when the team meeting finally ended. No broken whiteboards, no signs of trouble, and many players were cracking jokes. “We had a meeting? I didn’t know,” Embiid said, which was his way of letting reporters know that he wasn’t going to spill the tea on anything that got said behind closed doors. He did concede, however, that he might need to be more aggressive going forward. The 76ers are figuring out how to make all the pieces fit, but Embiid knows they can’t keep going down this path. “We’ve got that record,” Embiid said, “and something needs to be done about it.” The Associated Press contributed to this article"Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum." Section 1.10.32 of "de Finibus Bonorum et Malorum", written by Cicero in 45 BC "Sed ut perspiciatis unde omnis iste natus error sit voluptatem accusantium doloremque laudantium, totam rem aperiam, eaque ipsa quae ab illo inventore veritatis et quasi architecto beatae vitae dicta sunt explicabo. Nemo enim ipsam voluptatem quia voluptas sit aspernatur aut odit aut fugit, sed quia consequuntur magni dolores eos qui ratione voluptatem sequi nesciunt. Neque porro quisquam est, qui dolorem ipsum quia dolor sit amet, consectetur, adipisci velit, sed quia non numquam eius modi tempora incidunt ut labore et dolore magnam aliquam quaerat voluptatem. Ut enim ad minima veniam, quis nostrum exercitationem ullam corporis suscipit laboriosam, nisi ut aliquid ex ea commodi consequatur? Quis autem vel eum iure reprehenderit qui in ea voluptate velit esse quam nihil molestiae consequatur, vel illum qui dolorem eum fugiat quo voluptas nulla pariatur?" 1914 translation by H. Rackham "But I must explain to you how all this mistaken idea of denouncing pleasure and praising pain was born and I will give you a complete account of the system, and expound the actual teachings of the great explorer of the truth, the master-builder of human happiness. No one rejects, dislikes, or avoids pleasure itself, because it is pleasure, but because those who do not know how to pursue pleasure rationally encounter consequences that are extremely painful. Nor again is there anyone who loves or pursues or desires to obtain pain of itself, because it is pain, but because occasionally circumstances occur in which toil and pain can procure him some great pleasure. To take a trivial example, which of us ever undertakes laborious physical exercise, except to obtain some advantage from it? But who has any right to find fault with a man who chooses to enjoy a pleasure that has no annoying consequences, or one who avoids a pain that produces no resultant pleasure?" 1914 translation by H. Rackham "But I must explain to you how all this mistaken idea of denouncing pleasure and praising pain was born and I will give you a complete account of the system, and expound the actual teachings of the great explorer of the truth, the master-builder of human happiness. No one rejects, dislikes, or avoids pleasure itself, because it is pleasure, but because those who do not know how to pursue pleasure rationally encounter consequences that are extremely painful. Nor again is there anyone who loves or pursues or desires to obtain pain of itself, because it is pain, but because occasionally circumstances occur in which toil and pain can procure him some great pleasure. To take a trivial example, which of us ever undertakes laborious physical exercise, except to obtain some advantage from it? But who has any right to find fault with a man who chooses to enjoy a pleasure that has no annoying consequences, or one who avoids a pain that produces no resultant pleasure?" 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New York State Police Issue Warning Over Troubling Drone Sightings
ROUYN-NORANDA, Quebec, Dec. 03, 2024 (GLOBE NEWSWIRE) -- GLOBEX MINING ENTERPRISES INC. (GMX - Toronto Stock Exchange, G1MN - Frankfurt, Stuttgart, Berlin, Munich, Tradegate, Lang & Schwarz, LS Exchange, TTMzero, Düsseldorf and Quotrix Düsseldorf Stock Exch anges and GLBXF - OTCQX International in the US) is pleased to provide an update regards drilling by Cartier Resources Inc. (ECR-TSXV, 6CA-FSE) on Globex's Nordeau West claims directly east of the Chimo Gold Mine. New assays have been reported from the VG10 and VG10 South structures on the Nordeau West Royalty claims on which Globex retains a 3% Gross Metal Royalty. Drill results include the following: For detailed information on the drill program, please click here to access Cartier's December 3, 2024 and August 27, 2024 press releases. Globex retains a 3% Gross Metal Royalty on the Nordeau East, Nordeau West and east Bateman claims. East Cadillac Property - Cartier Resources Longitudinal Section VG9 and VG10 Gold Zones - Cartier Resources This press release was written by Jack Stoch, P. Geo., President and CEO of Globex in his capacity as a Qualified Person (Q.P.) under NI 43-101. LEI 529900XYUKGG3LF9PY95 President & CEO Globex Mining Enterprises Inc. 86, 14 th Street Rouyn-Noranda, Quebec Canada J9X 2J1 Tel.: 819.797.5242 Fax: 819.797.1470 [email protected] www.globexmining.com Forward Looking Statements: Except for historical information, this news release may contain certain "forward looking statements”. These statements may involve a number of known and unknown risks and uncertainties and other factors that may cause the actual results, level of activity and performance to be materially different from the expectations and projections of Globex Mining Enterprises Inc. ("Globex”). No assurance can be given that any events anticipated by the forward-looking information will transpire or occur, or if any of them do so, what benefits Globex will derive therefrom. A more detailed discussion of the risks is available in the "Annual Information Form” filed by Globex on SEDARplus.ca . Photos accompanying this announcement are available at: https://www.globenewswire.com/NewsRoom/AttachmentNg/23f9f1ad-74e3-485b-bc69-2ddaf7c0193b https://www.globenewswire.com/NewsRoom/AttachmentNg/7dd2eff1-2c58-46f1-9eae-057b97a61d25AP Business SummaryBrief at 5:25 p.m. EST