Healthy elbow room: Social distancing in Neolithic mega-settlements - Phys.org
Aircraft Generators Market Powering Aviation Systems with Reliable Energy Solutions
SAN FRANCISCO , Dec. 26, 2024 /PRNewswire/ -- AusperBio Therapeutics, Inc . and Ausper Biopharma Co., Ltd . (collectively AusperBio ), a privately held clinical-stage biotechnology company dedicated to advancing targeted oligonucleotide therapies to achieve a functional cure for chronic hepatitis B ( CHB ), today announced the successful completion of a USD 73 million Series B financing. The round was led by HanKang Capital , with participation from Sherpa Capital , CDH Investments , and a strategic investor, as well as continued participation from existing investors Qiming Venture Partners , InnoPinnacle Fund , and YuanBio Venture Capital . This financing followed the company's Series A round completed in July this year, demonstrating continued investor confidence in its proprietary platform and strategic direction. The proceeds will fund the continued Phase 2 development of AHB-137 , AusperBio's lead investigational therapy, supporting both clinical studies in China and global trials, as well as the development of commercial-scale manufacturing processes. The funding will also facilitate the expansion of the company's therapeutic pipeline and operational capabilities to drive sustained growth. Dr. Guofeng Cheng , co-founder and CEO of AusperBio, stated, " We are honored by our investors' confidence and support. This milestone financing recognizes our scientific and clinical accomplishments to date and enables us to accelerate our clinical programs and move closer to delivering a functional cure for CHB patients in need." Dr. Chris Yang , co-founder and CSO, added, "AHB-137 continues to attract attention from the scientific and clinical communities, particularly after the late-breaking oral presentation at the recent AASLD conference. The promising clinical data further validates our Med-OligoTM platform, strengthening our development of groundbreaking targeted oligonucleotide therapies for CHB and other serious chronic diseases." AusperBio is committed to delivering patient-centered innovations, aiming to alleviate the global health burden of CHB and transform treatment paradigms for this serious chronic disease. About AHB-137 AHB-137, a novel unconjugated antisense oligonucleotide ( ASO ) developed within AusperBio's proprietary Med-OligoTM ASO technology platform, was designed to treat chronic hepatitis B for a functional cure. Its compelling preclinical and Phase 1 clinical data were highlighted at the 2023 EASL conference and the 2024 EASL conference, respectively. Interim Phase 2a data was presented in a late-breaking oral session at the 2024 AASLD. This novel dual-mechanism ASO has completed its global Phase 1b trial and is now undergoing multiple Phase 2 trials in China . With its global development strategy, AHB-137 is advancing rapidly toward the goal of an HBV cure. About AusperBio. AusperBio is a clinical-stage biopharmaceutical company with operations in the USA and China , dedicated to advancing oligonucleotide and targeted delivery technologies for transformative therapies, with an initial focus on curing chronic hepatitis B infection. The company has developed a proprietary Med-OligoTM ASO platform which has been shown to substantially enhance the current ASO therapeutics, through novel insights into ASO design. Combining with efficient targeted delivery conjugation technologies, the modular Med-OligoTM Platform empowers ASO therapeutics to treat a broad range of diseases, including viral infections, metabolic conditions, genetic disorders, and immune diseases. For further information, please contact: Media Contact Email: info@ausperbio.com Investor Relations Contact: Tel: 650-888-1756 (US) Email: growth@ausperbio.com View original content to download multimedia: https://www.prnewswire.com/news-releases/ausperbio-secures-73-million-in-series-b-financing-to-advance-functional-cure-for-chronic-hepatitis-b-302339451.html SOURCE AusperBio Therapeutics Inc.49ers’ Purdy throws without pain, while it’s wait and see with Bosa, Williams
Alberta’s government said it will invest up to $50 million to support the creation of a first-in-Canada drilling test site to support technology development in the oil, gas, geothermal and lithium industries. The Alberta Drilling Accelerator is intended to be an open-access, industry-led site where companies can test drilling technologies at deep depths, high temperatures and varying rock types. A location for the hub site has yet to be determined. While no binding contracts have been signed, the province said several companies have expressed strong interest in serving as anchor tenants, including Calgary-based geothermal company Eavor Technologies, Tourmaline Oil Corp. and international oilfield service supermajor Halliburton. The money the province is providing will come from the industry-funded Technology Innovation and Emissions Reduction (TIER) program, which Alberta’s heavy emitters are required to pay into as part of the province’s industrial carbon pricing system. The provincial government said the Alberta Drilling Accelerator could start operating in 2026.Opinion: Growing up in the crossfire of America’s bitter politics took a heavy toll
Memphis and Chicago meet for the second time this year after a 126-123 shootout in the first meeting. Chicago enters 7-10 on the season and is 2-3 in the past five games. The Bulls are 2-5 at home this year and are coming off a 136-122 victory over the Hawks last night. Chicago is 1-2 on the second night of back-to-backs this season and has leaned heavily on Zach LaVine, as he’s led the team in scoring in five out of the last seven games. Memphis is 9-7 on the year but 2-3 over the last five games. Memphis had had off two days entering this matchup, so the Grizzlies have a heavy rest advantage. However, Memphis is 1-3 in the past four road games and dealing with injuries to Ja Morant and Marcus Smart. With that said, let’s dive into the matchup and offer some information and possibly a sweat or two. We’ve got all the info and analysis you need to know ahead of the game, including the latest info on how to catch the opening tip, projected lineups, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts. Listen to the Rotoworld Basketball Show for the latest player news, waiver claims, roster advice and more from our experts all season long. Details & how to watch Grizzlies @ Bulls ● Date: Saturday, November 23, 2024 ● Time: 8:10 PM ET ● Site: United Center ● City: Chicago, IL ● TV/Streaming: NBA TV Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page , along with detailed matchup pages that update live in-game with every out. Game odds for Grizzlies @ Bulls The latest odds as of Thursday afternoon: ● Moneyline: Memphis Grizzlies (-220), Chicago Bulls (+180) ● Spread: Memphis -5.5 (-110) ● Total: 240.0 Bet the Edge is your source for all things sports betting. Get all of Jay Croucher and Drew Dinsick’s insight on weekdays at 6AM ET right here or wherever you get your favorite podcasts. Probable starting lineups for Memphis and Chicago · Memphis Grizzlies (9-7) PG Scotty Pippen Jr. -- Ja Morant is out SG Jaylen Wells -- Marcus Smart is out SF Desmond Bane PF Jaren Jackson Jr. C Brandon Clarke · Chicago Bulls (6-10) PG Josh Giddey SG Coby White SF Zach LaVine PF Torrey Craig — Patrick Williams is out C Nikola Vucevic Top betting trends & insights to know ahead of Grizzlies @ Bulls Chicago is 7-9 ATS this season Memphis is 10-6 ATS this season, ranking top 10 Memphis is 11-5 to the Over, ranking third-best in the NBA. Chicago is 9-7 to the Over and 3-3 on the total as the home team. Memphis is 5-2 to the Over on the road, ranking second-best. Jaren Jackson scored at least 20 points in eight of the past 10 games. Desmond Bane scored at least 17 points in 5 out of 9 games. Zach LaVine scored 20 or more points in 9 out of 13 games. Nikola Vucevic scored 20 or more points in 6 of the past 11 games. Notable Player Props for Grizzlies @ Bulls Highest Point Props Zach LaVine O/U 23.5 Points Jaren Jackson Jr. O/U 22.5 Points Desmond Bane O/U 22.5 Points Nikola Vucevic O/U 19.5 Points Coby White O/U 18.5 Points Highest Rebound Props Nikola Vucevic O/U 10.5 Rebounds Jaren Jackson Jr. O/U 6.5 Rebounds Josh Giddey O/U 6.5 Rebounds Desmond Bane O/U 5.5 Rebounds Brandon Clarke O/U 5.5 Rebounds Highest Assist Props Desmond Bane O/U 5.5 Assists Scotty Pippen Jr. O/U 5.5 Assists Josh Giddey O/U 5.5 Assists Coby White O/U 4.5 Assists Expert picks & predictions for Grizzlies @ Bulls Please bet responsibly. If you or someone you know has a gambling problem, call the National Gambling Helpline at 1-800-522-4700. NBC Sports Bet Best Bet Vaughn Dalzell (@VmoneySports) likes the Grizzlies to go Over the First Half Team Total of 60.5 versus the Bulls: “The Bulls won the first meeting 126-123 and the Grizzlies led at halftime 68-54. This time around, Memphis has a significant rest advantage with two days off and Chicago played and won, 136-122 against Atlanta last night. Chicago allowed 51, 69, 57, 68, and 77 first-half points over the past five games (64.4 1H PPG), so the defense isn’t exactly stopping much of anyone. These teams only met twice last year and both games stayed Under the total, but I think sparks can fly in this one. Chicago and Memphis are ranked first and third in the league for pace and are top seven in possessions this year. The Bulls have the 25th-ranked defensive efficiency and 28th over the last five games. I like the Grizzlies to get off to a fast start in the first half and go Over 60.5 points.” Here are the best bets our model is projecting for the Grizzlies and the Bulls: · Moneyline : NBC Sports finds confidence in taking Memphis on the ML (-220) · Spread : NBC Sports has strong confidence in Memphis -5.5 on the spread · Total : NBC Sports has low confidence towards a play on the Total UNDER 240.5 points Want even more NBA best bets and predictions from our expert staff & tools? Check out the EXPERT NBA Predictions page from NBC Sports for money line, spread and total picks for each of the games on today’s calendar! Follow our experts on socials to keep up with all the latest content from the staff: · Jay Croucher (@croucherJD) · Drew Dinsick (@whale_capper) · Vaughn Dalzell (@VmoneySports) · Brad Thomas (@MrBradThomas)
From British rule in India to cinema actors turning politicians, the predictions of Potuluri Veera Brahmendra Swamy have intrigued generations. Known for his remarkable foresight, Brahmendra Swamy authored the Kalagnanam, a book containing over 14,000 prophecies in Telugu poetry, offering a glimpse into the future of the world. While modern technology enables us to predict natural disasters like cyclones and famines, Brahmendra Swamy’s predictions continue to captivate us with their uncanny accuracy. Here are the 20 predictions by Potuluri Veera Brahmendra Swamy that came true. World Wars and Disasters - Brahmendra Swamy predicted that the 5000 years of Kaliyuga would be marked by devastating events, including natural disasters and wars. The 1939-1945 World War II and the 2004 Indian Ocean Tsunami, which killed over 230,000 people, align with his predictions of massive destruction. British Rule in India - Swamy’s prophecy about "fair-faced people" ruling India came true with the British colonization, where the British controlled India for nearly 200 years. A Woman Would Rule for 16 Years - He predicted that a woman would rule for 16 years, which matches the tenure of Indira Gandhi, India’s first female Prime Minister, who ruled from 1966-1977 and again from 1980-1984. The Advent of Automobiles - The "non-living vehicles" predicted by Swamy refer to the invention of cars, trains, and planes, which revolutionized transportation. Electricity and Hydroelectric Power - He foresaw that "lamps would be lit with water," symbolizing the development of electricity and hydroelectric power, where water is used to generate energy. Fraudulent Gurus - Swamy predicted that genuine spiritual teachers would be rare, and fraudulent ones would be plentiful. This reflects the rise of self-proclaimed gurus today. End of Monarchies, Rise of Democracy - He predicted that traditional monarchies would end, and democracies would rise. This is seen in India after independence in 1947 when democracy replaced monarchy. San Francisco Earthquake - Swamy predicted a huge earthquake in San Francisco, which occurred in 1906, causing significant destruction. Cinema Actors Turned Politicians - Swamy’s prediction that "images on the screen would rule countries" has come true with film stars like N.T. Rama Rao, M.G. Ramachandran, and Arnold Schwarzenegger entering politics. Global Mobility - Swamy predicted that people would move constantly for work or other reasons, which is true in today’s globalized world. Decline in Social Morality - Swamy predicted that immoral actions, like the sale of children and increased affairs, would become common. These issues are being reported more today. Rise of Cruel Husbands - He predicted the rise of cruel husbands who treat their wives poorly. Unfortunately, this is seen in many instances of domestic violence today. Religious Conflicts - Swamy warned that conflicts based on religion would harm humanity, which is evident in ongoing religious extremism and terrorism. Rising Oceans and Global Warming - Swamy’s prophecy about rising oceans swallowing cities aligns with today’s fears of global warming and rising sea levels. Foreigners in Power and New Education Systems - Swamy predicted that foreigners would rule and bring a new education system. This happened with British colonial rule, which introduced Western education systems in India. Extinction of Wild Animals - Swamy foresaw the extinction of wild animals like lions due to poaching and habitat destruction, with many species now endangered.Selling of Merit - Swamy predicted that people would prioritize money over merit, seen today in education where management quotas and donations often replace merit-based admissions. Musi River Flood in Hyderabad - Swamy predicted the Musi River flood in Hyderabad, which happened in 1908, causing widespread destruction. Adulteration of Goods - He foresaw widespread adulteration of food and goods, which is a common issue today with fake products and compromised quality. The Birth of Gandhi - Swamy’s mention of a great soul named "Gandhi" refers to Mahatma Gandhi, who led India to independence through non-violence. Disclaimer: This article is based on popular beliefs. Times Now is not responsible for the accuracy or completeness of the information and facts provided here. Get Latest News Live on Times Now along with Breaking News and Top Headlines from Astrology and around the world.NoneJayden Daniels and the offense stalling have the Commanders on a three-game losing streak
Vikings defense has had a big boost this season from the indefatigable Jonathan Greenard
Adele says it is time to ‘move on’ after completing her Las Vegas residency
Santa Clara councilmember who implicated Anthony Becker in 49ers leak says he was ‘confused’
Nebraska saw a football player announce a transfer for a third straight day Wednesday, this time a rotational member of the defensive line. Kai Wallin will move on after two seasons as a Husker, he announced on social media. He appeared in 11 games this fall with four tackles and recorded half a sack at Purdue. The 6-foot-5, 250-pounder said he “deliberated, consulted and prayed” about his decision. “While I hope to continue to grow and evolve and make an impact on a new field, I will never forget the honor it was to wear a Nebraska jersey,” Wallin wrote in part. Wallin played a year of junior-college ball before arriving at Nebraska in 2023. The Sacramento native redshirted his first season before logging 89 snaps this year including 13 against Wisconsin. He saw single-digit snaps in five games behind a senior-heavy starting line. The defender has two years of eligibility remaining. Wallin is the 10th Husker to announce his intent to enter the transfer portal since Nov. 25. Migration among defenders has been higher as defensive coordinator Tony White and defensive line coach Terrance Knighton both left in recent days for Florida State. NU coach Matt Rhule said earlier Wednesday the roster churn – especially attrition – will continue in earnest as the team continues to trim closer to next season’s mandated limit of 105. “There’s going to be more,” Rhule said. “Everybody’s journey is different.” Get local news delivered to your inbox!
SAN JOSE, Calif., Dec. 04, 2024 (GLOBE NEWSWIRE) -- Adeia Inc. (Nasdaq: ADEA), the company whose patented innovations shape the way the world explores and experiences entertainment, today announced that Sharp Corporation, a global smart TV and consumer electronics manufacturer, has agreed to renew a multi-year worldwide license for Adeia's media intellectual property (IP) portfolio. This multi-year agreement extends the longstanding relationship between the two companies, encompassing Adeia's expansive media IP portfolio. "We are pleased to continue our 25-plus year partnership with Sharp, which, for decades, has been a global leader in consumer electronics. Sharp is a global brand that has maintained a strong reputation as a leader in entertainment technology. The company is well known for its expertise in display technologies, offering a range of smart TVs and consumer electronics that deliver high-quality experiences to consumers worldwide," said Dr. Mark Kokes, Adeia's chief licensing officer and general manager, media. About Adeia Adeia is a leading R&D and technology licensing company that accelerates the adoption of innovative technologies in the media and semiconductor industries. Adeia’s fundamental innovations underpin technology solutions that are shaping and elevating the future of digital entertainment and electronics. Adeia’s IP portfolios power the connected devices that touch the lives of millions of people around the world every day as they live, work and play. For more, please visit www.adeia.com . For Information Contact: Investor Relations Chris Chaney IR@adeia.com Media Relations JoAnn Yamani press@adeia.comRethinking Infrastructure Scaling With Context And Flexibility
By WYATTE GRANTHAM-PHILIPS NEW YORK (AP) — Sneaking a little ahead of line to get on that plane faster? American Airlines might stop you . In an apparent effort to reduce the headaches caused by airport line cutting, American has rolled out boarding technology that alerts gate agents with an audible sound if a passenger tries to scan a ticket ahead of their assigned group. This new software won’t accept a boarding pass before the group it’s assigned to is called, so customers who get to the gate prematurely will be asked to go back and wait their turn. As of Wednesday, the airline announced, the technology is now being used in more than 100 U.S. airports that American flies out of. The official expansion arrives after successful tests in three of these locations — Albuquerque International Sunport, Ronald Reagan Washington National Airport and Tucson International Airport. The initial response from customers and American employees “has exceeded our expectations,” Julie Rath, American’s senior vice president of airport operations, reservations and service recovery, said in a statement. She added that the airline is “thrilled” to have the technology up and running ahead of the Thanksgiving holiday . American got lots of attention when it unveiled its gate-control testing last month. Analysts say that isn’t surprising. It’s no secret that line cutting in airports hits a nerve. Whether intentional or not, just about every air traveler has witnessed it, noted Henry Harteveldt, an airline industry analyst with Atmosphere Research Group. It can add to frustrations in what can already be a tense environment, with particular anxiety around passengers wanting to sit together or rushing for some overhead bin space. Harteveldt doesn’t see American’s recent move as “shaming” customers who cut the line. “What it is intended to do is bring order out of chaos,” he said. “And I hope it will defuse any potential flare ups of anger (from) people who simply think they’re entitled to board out of turn .... It’s just not fair.” Harteveldt added that he thinks this change will enhance the experiences of both customers and gate agents. Others say more time will tell. Seth Miller, editor and founder of air travel experience analysis site PaxEx.aero, said he can see the benefits of more orderly and universal gate-control enforcement, particularly for airlines. But he said he isn’t “100% convinced this is perfect for passengers” just yet. Families, for example, might be booked on several different reservations across more than one group, he said. Airlines typically have workarounds for that, and American noted Wednesday that customers traveling with a companion in an earlier group can simply have a gate agent “override the alert” to continue boarding. Still, Miller said, “you have to go through the extra hoops.” And a difficult customer still might choose to hold up the line and argue when they’re not allowed to board, he added. Related Articles National News | A Mexican cartel leader arrested in the US faked his death and assumed a phony name, prosecutors say National News | Major storm drops record rain, downs trees in Northern California after devastation further north National News | SEC Chair Gary Gensler, who led US crackdown on cryptocurrencies, to step down National News | ACLU sues government for records detailing Trump’s mass deportation plan National News | Jussie Smollett’s conviction in 2019 attack on himself is overturned Another question is whether customers who encounter a beep will walk away feeling embarrassed. But Harteveldt said he was happy to learn that American’s alert is “not a bellowing sound that can be heard throughout the terminal,” or accompanied by your name read over a loudspeaker, noting that this is important to avoid feelings of shame. Expanding this technology just a week before peak Thanksgiving travel could be “both good and bad,” Harteveldt adds. On one hand, the tech could help significantly improve the boarding process during such a busy time, he said, but airport employees might also have appreciated more time to prepare. Both Miller and Harteveldt said they wouldn’t be surprised if other carriers soon follow American’s lead. Headaches over airport line cutting are far from new. While maybe not to the extent of American’s new tech, Miller noted he’s seen gate agents from other airlines ask people to leave a line and wait for their group. Harteveldt added that he’s been to some airports in Asia and Europe with “sliding doors” that ensure passengers are in the right group before boarding a plane. The more than 100 airports that American is now using its gate-control technology in are all spoke, or non-hub, locations — including Austin-Bergstrom International Airport and Hartsfield-Jackson Atlanta International Airport. The airline says it expects to further expand to its hubs and other airports in the coming months.