New research highlights AI's potential and pitfalls in scouring health data
December 2, 2024 This article has been reviewed according to Science X's editorial process and policies . Editors have highlightedthe following attributes while ensuring the content's credibility: fact-checked peer-reviewed publication trusted source proofread by American Chemical Society A group of young students became bonafide biomedical scientists before they even started high school. Through a partnership with a nearby university, the middle schoolers collected and analyzed environmental samples to find new antibiotic candidates. One unique sample, goose poop collected at a local park, had a bacterium that showed antibiotic activity and contained a novel compound that slowed the growth of human melanoma and ovarian cancer cells in lab tests. Inequities in educational resources, especially those in science, engineering, technology and math (STEM), where experiments are expensive, have kept some students underrepresented in these fields. By engaging a group of these students early in real, high-quality research, a team from the University of Illinois at Chicago led by Brian Murphy is providing young learners a chance to see themselves as scientists and explore careers in science with hands-on experience. The team partnered with a Boys and Girls Club in Chicago to bring interested middle schoolers into a 14-week applied science program. Murphy's lab is focused on discovering antibiotics from natural sources, and the cohort of young scientists participated by supplying environmental samples from their local communities. And the students' contributions to the research group didn't end there. They stayed actively involved throughout the scientific discovery process by programming a specialized robot to scoop up bacterial colonies from growth plates and test them for antibiotic activity. One of the 14 samples collected—goose poop from the Garfield Park Lagoon—contained a strain of bacteria called Pseudomonas idahonensis. The students interpreted the bacterium's bioassay data and concluded it had antibiotic activity and produced a never-before-seen compound. Then, the university researchers determined the compound's molecular structure using nuclear magnetic resonance and mass spectrometry , named it orfamide N after the family of molecules it belongs to, and investigated its biological activity. Although orfamide N was not responsible for the antibiotic activity that the team initially observed from P. idahonensis, the compound inhibited the growth of human melanoma and ovarian cancer cells in culture tests. Further studies could reveal other advantageous properties of this newly characterized molecule. The researchers say that this work proves that it's possible to combine educational outreach with natural product discovery research, and it emphasizes the importance of a strong relationship between universities and their local communities. The study is published in the journal ACS Omega . More information: Jin Yi Tan et al, Discovery of New Cyclic Lipodepsipeptide Orfamide N via Partnership with Middle School Students from the Boys and Girls Club, ACS Omega (2024). DOI: 10.1021/acsomega.4c07459 Journal information: ACS Omega Provided by American Chemical SocietyPresident-elect Donald Trump, House Speaker Mike Johnson to meet at Army-Navy Game
More than 250 state and local organizations are urging New York Gov. Kathy Hochul to include a package of food and nutrition priorities in her upcoming executive budget proposal, according to a letter sent to the governor. The groups are requesting: “Our organizations recognize that these initiatives alone will not end hunger and poverty in New York State,” the letter, dated Dec. 4, reads. “It is without question that more is needed to strengthen wages; ensure access to affordable housing, childcare, and health care; and address systemic injustices that perpetuate inequality. However, through these investments, we can meet urgent food security needs and help affirm healthy food as a basic human right for all New Yorkers.” The requests come following a report in May from the state comptroller’s office finding that food insecurity rates rose significantly in 2022, coinciding with the expiration of COVID-era initiatives like SNAP Emergency Allotments, child nutrition waivers that allowed schools to provide universal free school meals and the temporary child tax credit expansion. Hochul will outline her executive budget proposals in January. document.write(__reporter_name); - document.write(__reporter_title); document.write(__reporter_bio);
Ancient meets modern as a new subway in Greece showcases archaeological treasures THESSALONIKI, Greece (AP) — Thessaloniki, Greece’s second-largest city, is opening a new subway system, blending ancient archaeological treasures with modern transit technology like driverless trains and platform screen doors. The project, which began in 2003, uncovered over 300,000 artifacts, including a Roman-era thoroughfare and Byzantine relics, many of which are now displayed in its 13 stations. Despite delays caused by preserving these findings, the inaugural line has been completed, with a second line set to open next year. Conor McGregor must pay $250K to woman who says he raped her, civil jury rules LONDON (AP) — A civil jury in Ireland has awarded more than $250,000 to a woman who says she was raped by mixed martial arts fighter Conor McGregor in a Dublin hotel penthouse after a night of heavy partying. The jury on Friday awarded Nikita Hand in her lawsuit that claimed McGregor “brutally raped and battered” her in 2018. The lawsuit says the assault left her heavily bruised and suffering from post-traumatic stress disorder. McGregor testified that he never forced her to do anything and that Hand fabricated her allegations after the two had consensual sex. McGregor says he will appeal the verdict. At least 19 people are sick in Minnesota from ground beef tied to E. coli recall U.S. health officials say at least 19 people in Minnesota have been sickened by E. coli poisoning tied to a national recall of more than 167,000 pounds of potentially tainted ground beef. Detroit-based Wolverine Packing Co. recalled the meat this week after Minnesota state agriculture officials reported multiple illnesses and found that a sample of the product tested positive for E. coli O157:H7, which can cause life-threatening infections. Symptoms of E. coli poisoning include fever, vomiting, diarrhea and signs of dehydration. Kendrick Lamar surprises with new album 'GNX' LOS ANGELES (AP) — Kendrick Lamar gave music listeners an early holiday present with a new album. The Grammy winner released his sixth studio album “GNX” on Friday. The 12-track project is the rapper’s first release since 2022’s “Mr. Morale & The Big Steppers.” Lamar’s new album comes just months after his rap battle with Drake. The rap megastar will headline February's Apple Music Super Bowl Halftime Show in New Orleans. The 37-year-old has experienced massive success since his debut album “good kid, m.A.A.d city” in 2012. Since then, he’s accumulated 17 Grammy wins and became the first non-classical, non-jazz musician to win a Pulitzer Prize. Actor Jonathan Majors’ ex-girlfriend drops assault and defamation lawsuit against once-rising star NEW YORK (AP) — Jonathan Majors’ ex-girlfriend has dropped her assault and defamation lawsuit against the once-rising Hollywood star after reaching a settlement. Lawyers for Majors and Grace Jabbari agreed to dismiss the case with prejudice Thursday. Jabbari is a British dancer who had accused Majors of subjecting her to escalating incidents of physical and verbal abuse during their relationship. Representatives for Majors didn’t respond to emails seeking comment Friday. Jabbari’s lawyer said the suit was “favorably settled” and her client is moving on with “her head held high.” Majors was convicted of misdemeanor assault and harassment last December and sentenced to a yearlong counseling program. Hyundai, Kia recall over 208,000 electric vehicles to fix problem that can cause loss of power DETROIT (AP) — Hyundai and Kia are recalling over 208,000 electric vehicles to fix a pesky problem that can cause loss of drive power, increasing the risk of a crash. The recalls cover more than 145,000 Hyundai and Genesis vehicles including the 2022 through 2024 Ioniq 5, the 2023 through 2025 Ioniq 6, GV60 and GV70, and the 2023 and 2024 G80. Also included are nearly 63,000 Kia EV 6 vehicles from 2022 through 2024. The affiliated Korean automakers say in government documents that a transistor in a charging control unit can be damaged and stop charging the 12-volt battery. Dealers will inspect and replace the control unit and a fuse if needed. They also will update software. Christmas TV movies are in their Taylor Swift era, with two Swift-inspired films airing this year Two of the new holiday movies coming to TV this season have a Taylor Swift connection that her fans would have no problem decoding. “Christmas in the Spotlight” debuts Saturday on Lifetime. It stars Jessica Lord as the world’s biggest pop star and Laith Wallschleger, playing a pro football player, who meet and fall in love, not unlike Swift and her boyfriend, Kansas City Chiefs tight end Travis Kelce. On Nov. 30, Hallmark will air “Holiday Touchdown: A Chiefs Love Story.” Instead of a nod to Swift, it’s an ode to family traditions and bonding, like rooting for a sports team. Hallmark’s headquarters is also in Kansas City. Top football recruit Bryce Underwood changes commitment to Michigan instead of LSU, AP source says ANN ARBOR, Mich. (AP) — Top football recruit Bryce Underwood has flipped to Michigan after pledging to play at LSU. That's according to a person familiar with the situation who spoke to The Associated Press on condition of anonymity because they were not authorized to share the recruit’s plans to join the Wolverines. Underwood pinned a post on his Instagram account, showing a post in which On3.com reported that he has committed to Michigan. The 6-foot-3 quarterback played at Belleville High School about 15 miles east of Michigan's campus, and told LSU nearly a year ago he intended to enroll there. Emperor penguin released at sea 20 days after waddling onto Australian beach MELBOURNE, Australia (AP) — The only emperor penguin known to have swum from Antarctica to Australia has been released at sea 20 days after he waddled ashore on a popular tourist beach. The adult male was found on Nov. 1 on sand dunes in temperate southwest Australia about 2,200 miles north of the Antarctic coast. He was released Wednesday from a boat that traveled several hours from Western Australia state's most southerly city of Albany. His caregiver Carol Biddulph wasn't sure at first if the penguin would live. She said a mirror was important to his rehabilitation because they provide a sense of company. Biddulph said: “They’re social birds and he stands next to the mirror most of the time.” Shohei Ohtani wins third MVP award, first in NL. Aaron Judge earns second AL honor in 3 seasons NEW YORK (AP) — Shohei Ohtani won his third Most Valuable Player Award and first in the National League, and Aaron Judge earned his second American League honor on Thursday. Ohtani was a unanimous MVP for the third time, receiving all 30 first-place votes and 420 points in voting by the Baseball Writers’ Association of America. New York Mets shortstop Francisco Lindor was second with 263 points and Arizona second baseman Ketel Marte third with 229. Judge was a unanimous pick for the first time. Kansas City shortstop Bobby Witt Jr. got all 30 second-place votes for 270 points, and Yankees outfielder Juan Soto was third with 21 third-place votes and 229 points.Biden's broken promise on pardoning his son Hunter is raising new questions about his legacy
None
None
Texas Democrat Blasts Republican 'Pearl Clutching' Over Hunter Biden: 'Convicted Felon About To Walk Into White House'Trudeau says dealing with Trump will be ‘a little more challenging’ than last time
ISD 518 Operations Committee continue high school facility discussion