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Donald Trump is reiterating his threat to impose steep tariffs on Canadian goods if the federal government doesn't take action on border security — and a former official from his first administration says the U.S. president-elect isn't bluffing. "I'm a big believer in tariffs. I think tariffs are the most beautiful word.... It's going to make us rich," Trump said in an interview on NBC's Meet the Press that aired on Sunday. The president-elect continued to extol the power of tariffs and said they're "a powerful tool not only economically, but also for getting other things outside of economics." Analysis Trump's tariff threat is testing both Justin Trudeau and Pierre Poilievre As an example, Trump referred to his threat to slap a 25 per cent tariff on products from Canada and Mexico unless they curb the flow of drugs and migrants across their borders. Four days after the threat was issued, Prime Minister Justin Trudeau flew to Trump's estate in Florida for a surprise dinner. The president-elect joked about the saga in his NBC interview. "In fact, [Trudeau] flew to Mar-a-Lago within about 15 seconds after the call," Trump said. The president-elect also said he told Trudeau that Canada has to "close up" its border and that "drugs are pouring in at levels never seen before." "And I said to the president of Mexico and to Justin Trudeau, if it doesn't stop, I'm going to put tariffs on your country at about 25 per cent," Trump said. Prime Minister Justin Trudeau dined with U.S. president-elect Donald Trump in late November. Trump described the meeting as 'very productive' on his social media platform Truth Social. (@JustinTrudeau/X) Trump's threat is 'serious,' says former official Ken Cuccinelli, a former official in the Department of Homeland Security during Trump's first administration, said the president-elect's tariff threat is "very serious" given the issues at hand. "And I think one of the things that people around the world know about Donald Trump is that he will follow through with things like this," Cuccinelli said in an interview on Rosemary Barton Live that aired Sunday. When asked what he thinks can be done to protect the Canada-U.S. border, Cuccinelli said that he "wouldn't expect the president to give the prime minister a checklist." WATCH: Former official discusses Trump's border concerns and deportation plan: What will Canada-U.S. border security look like under Trump? 3 hours ago Duration 9:41 In a Canadian exclusive, CBC chief political correspondent Rosemary Barton speaks with Ken Cuccinelli, a former official in the Department of Homeland Security under Donald Trump, about what the U.S. president-elect expects from Canada on border security, and what his deportation plan could look like. The goal isn't "zero illegal crossings," he added. Instead, it's about driving them down to "the point where it's not worth people trying to, for example, come to Canada as a way to get into the United States." What Trump specifically wants from Canada in exchange for removing his tariff threat still isn't clear, according to Canadian officials familiar with the details of the surprise dinner in Florida. The federal government has made some announcements in the wake of the Trudeau-Trump meeting, including adding more helicopters and drones to tighten up monitoring of the Canada-U.S. border. Canada to buy helicopters, drones to meet Trump's demand for tighter border security The takeaway from Trudeau's trip to Mar-a-Lago: For Trump, fentanyl is priority No. 1 David Cohen, the outgoing U.S. ambassador to Canada, said the Biden administration has not proposed a 25 per cent across-the-board tariff because of concerns it would contribute to inflation and lead to job losses in both countries. "I think in the end, the value of that from a trade perspective is not going to be very compelling," he told Rosemary Barton. Cohen also said there's a "pretty clear window" for Canada and the United States to work through the issues underlying Trump's tariff threat.Five-year results confirm Roche’s Polivy combination therapy as new standard of care for previously untreated aggressive lymphoma
New York Jets interim coach Jeff Ulbrich said Aaron Rodgers “absolutely” will remain the team's starting quarterback and start Sunday against the Seattle Seahawks. Rodgers, who turns 41 next Monday, has been hampered at times during the Jets' 3-8 start by various injuries to his left leg, including a sore knee, sprained ankle and balky hamstring. Ulbrich said Monday the quarterback came back from the team's bye-week break ready to go. “All I can say, and you'd have to ask Aaron if he's fully healthy, but he's better off today than he's been as of late,” Ulbrich said. "So he's definitely feeling healthier than he has probably for the past month. A healthy Aaron Rodgers is the Aaron Rodgers we all love. “So, I'm excited about what that looks like.” NFL Network reported on Sunday that Rodgers, who missed all but four snaps last season with a torn left Achilles tendon, has declined having medical scans on his injured leg so he can continue to play. GM: The New York Jets are turning to one of their former general managers to help them find their next GM and head coach. The franchise announced Monday that The 33rd Team, a football media, analytics and consulting group founded by former Jets GM Mike Tannenbaum, will assist team owner Woody Johnson in the searches. Tannenbaum and Rick Spielman, former GM of the Miami Dolphins and Minnesota Vikings, will be The 33rd Team's primary representatives in helping find replacements for former coach Robert Saleh and GM Joe Douglas. SANTA CLARA, Calif. — San Francisco quarterback Brock Purdy took part in some light throwing on Monday after missing his first career game because of an injury and the 49ers are hoping he can return this week. Purdy hurt his throwing shoulder during a loss to Seattle on Nov. 17. Purdy underwent two MRIs last week that showed no structural damage. But Purdy he felt discomfort after making a few throws at practice on Thursday and was shut down for the game at Green Bay on Sunday that San Francisco lost 38-10. Coach Kyle Shanahan said Monday that Purdy made it through the session without pain and will rest on Tuesday and hopefully be able to return to practice on Wednesday as the Niners prepare to play at Buffalo this coming week. “We rested it throughout the weekend hoping that would help,” Shanahan said. “He threw lighter today to see if that rest helps and the rest did help him. So we’ll see again, going through the same things we did last week. We’re going to let him rest all the way up to Wednesday. We’ll see how it feels on Wednesday and then we’ll take the exact same course throughout the week. Hopefully it responds better this week than it did last week with the rest.” Brandon Allen went 17 for 29 for 199 yards with a touchdown, an interception and a lost fumble in his first start since the 2021 season. Allen would play once again if Purdy is unable to go on Sunday at Buffalo. FOXBOROUGH, Mass. — The NFL removed New England Patriots safety Jabrill Peppers from the commissioner exempt list on Monday, making him eligible to participate in practice and play in the team’s games. Peppers missed seven games since being placed on the list on Oct. 9 after he was arrested and charged with shoving his girlfriend’s head into a wall and choking her. The league said its review is ongoing and is not affected by the change in Peppers’ roster status. Braintree, Massachusetts, police said they were called to a home for an altercation between two people on Oct. 7, and a woman told them Peppers choked her. Police said they found at the home a clear plastic bag containing a white powder, which later tested positive for cocaine. Peppers, 29, pleaded not guilty in Quincy District Court to charges of assault and battery with a dangerous weapon and possession of a Class “B” substance believed to be cocaine. At a court appearance last week a trial date was set for Jan. 22. HENDERSON, Nev. — Las Vegas Raiders quarterback Gardner Minshew is out for the rest of the season with a broken collarbone, coach Antonio Pierce said Monday. Minshew was injured with 3:12 left in Sunday's 29-19 loss to the Denver Broncos. Pierce will have to decide whether Aidan O'Connell or Desmond Ridder will start Friday's game at Kansas City. The Raiders, who have lost seven consecutive games to fall to 2-9, could use a spark. Minshew's grip on the starting job was tenuous even before he was injured. He threw 10 interceptions to just nine touchdown passes this season and Minshew also lost four fumbles. JACKSONVILLE, Fla. — Jacksonville Jaguars quarterback Trevor Lawrence will practice Monday and “we'll see where he's at from there,” coach Doug Pederson said. Lawrence missed the past two games, losses to Minnesota and Detroit, with a sprained left shoulder. Lawrence had extra time to rest during Jacksonville's bye week. The Jaguars (2-9) host AFC South-leading Houston (7-5) on Sunday and need a victory to avoid being eliminated from playoff contention. Pederson said Lawrence is “feeling better" and they will know more about his playing status following practice Wednesday. Lawrence took a hit to his left shoulder while scrambling at Philadelphia on Nov. 3. Instead of sliding, he chose to go head-first and got hammered by linebacker Zack Baun. Lawrence has practiced some in a limited role since, but was inactive for both games. BRIEFLY LIONS: Detroit wide receiver Jameson Williams won't be charged with a crime after he was found with a gun in a car driven by his brother in October. Prosecutor Kym Worthy says Michigan law is “far from clear” when applied to the 1 a.m. traffic stop in Detroit. Get local news delivered to your inbox!Raven Roundup: Men's basketball outruns CarthageInvestors can focus on these stock market themes in 2025
1. A remote organizer , perfect for keeping your various remotes, clickers, channel changers (whatever you call it in your house) in check so when your dad visits for the holidays and has grand plans to watch football he doesn't have to pester you to ask where it is while you're in the middle of making appetizers. You're only human if you don't know where your TV remotes are... ever. This contraption is perfect for storing remotes, house phones (if ya' have one), and even your cell phone if you want to really focus on what you're watching. Promising review: "This remote control holder is the best I’ve ever owned. Not only is it elegant and attractive, it is nice and lightweight, and has room for at least five remote controls, however depending on the thinness of the controllers, you could probably fit more in there. Since it basically just sits on a side table, I believe it’s made of quality material, and will last a very long time. It matched my decor perfectly, and looks exactly as pictured." — Nicole Cook Get it from Amazon for $24.44+ (available in three colors). 2. And a universal remote attachment in case your stash of remotes has managed to go awry (it's ridiculous that these days there are at least three you need to navigate to what you want to watch). This handy dandy attachment will help you get the Macy's Thanksgiving Day Parade on before it begins with just your Fire TV remote. Sideclick is a small business! Promising review: "Before: three remotes, one for the screen (on/off), a separate one for the sound system (volume) and of course the fire stick remote. After: just the one convenient integrated unit. No more scrambling to find the which remote to do what I want, cause it's all right there in the one unit. I wish I'd have bought one years ago cause the multi-remote tango got old real fast." — Chapman B. Get it from Amazon for $29.99 (also available for Chromecast and Apple TV remotes) 3. Washable microfiber mop pads you can use with your Swiffer WetJet and finally stop spending so much money on disposable options — perfect for after gatherings where everyone inevitably tracks dirt throughout your home. One pad can last up to 100 washes and works on pretty much any surface, from wood to tile to stone. Turbo Mops is a small business! Promising review: "These are life-changing. I used a Rubbermaid spray mop for years that I never really loved, and when it broke, I got a Swiffer and was using the old Rubbermaid mop cloth pads with it still. They didn't fit the Swiffer great and I decided to get new ones. These scrub so much better and pick up way more dirt than my other mop pad. I have two dogs, and their dried water and drool are around the kitchen, and I used to have to scrub to get that up each time. Not with these pads! I never thought I'd swoon over a cleaning product, but...here we are :). " — JB Get a pack of two from Amazon for $18.99 . 4. A lidded charcuterie board , because what kind of host would you be without the perfect vessel for transporting an array of meats and cheeses to your guests? You can prep this one in advance, pop the cover on it, then serve it when the time is right. Promising review : "I bought these for a party and it was so easy to prep them and pop them into the fridge with the lid on. Same goes for staring leftovers afterward. It was also great to use for fresh fruit we cut up to enjoy all weekend. Looks lovely and is solid quality. " — AmJam Get it from Amazon for $35.99 . 5. A height-adjustable tray table because before you know it you'll have accumulated so many family members and friends for the holidays you'll need some overflow seating at-the-ready. Table-Mate is a small business that specializes in height-adjustable table trays. Promising review : "This table is exactly what I was looking for to be able use my mouse and keyboard for the computer while working from home. It’s plenty stable and easily moved to the side for storage or when I need to get up from the chair. I also use it as my lunch table and to hold my iPad when not on the computer." — sleuneberg Get it from Amazon for $44.99+ (available in four colors). 6. A drink organizer and dispenser that'll help you live out your dreams of transforming your fridge into a majestic beverage haven (you know, just like the ones in convenience stores that seemingly have every drink known to man). Would it be so awful to fill the entire thing with Diet Cokes? Promising review: "This slides the drinks forward gently. It is adjustable and fits a variety of sizes. This is easy to assemble; it only took me a few moments. It keeps everything lined up nicely. I like how organized this makes my fridge look. The gears feel solid, but I'm not worried about it sitting on the glass shelf." — Jessie333 Get it from Amazon for $19.92 . 7. A set of clip-on dip bowls that'll transform any plate into a snack party — fill 'em with salsa alongside chips, ketchup with chicken fingers, ranch dressing paired with veggies... you catch my drift. Promising review: "These dip cups are easy to attach to your plates, filled with your favorite dipping sauces. No worries about them slipping off as they're sturdy. They're also dishwasher safe." — LJ Williams Get it from Amazon for $5.59 . 8. And a set of wineglass charcuterie toppers to make snacking on cheese and crackers a rather *~fabulous~* experience. Promising review : "These are so cute! I hosted a wine tasting at my house and the coasters fit into many different wine glasses. I had about three to four fairly decent size chocolates on top. These were a hit and everyone thought they were in a nice restaurant with the setup!!" — Melanie M. Get a set of four from Amazon for $9.99 (also available in a set of eight). 9. Espresso Martini Instant Cocktail Tea Bags that'll make tini time a lot easier to acheive instead of trying to whip up individual ones for each guest. All you'll need to do is steep the bag in cold water and a spirit of their choice (vodka or tequila is recommended, but it can also be made as mocktails) until the majority of the bag dissolves. Cheers to that! SAYSO is a small business! Promising review: "Initially thought these would need to steep in hot water, but they work in cold water. I like to let them steep around 10 minutes. Quick and delicious cocktails! I’ve tried all flavors but Old Fashioned, and that’s next. These are fantastic for cocktail lovers that camp. No heavy mixers to carry." — AnneF Get it from Amazon for $14.99 (available in six other cocktails and in a variety pack). 10. A bag of FryAway cooking oil solidifier — a seemingly magical substance you can sprinkle on top of your oily pan and watch as it turns to a solid. No more waiting ages for it to cool, having to grossly scrape it out of your pan with a paper towel, or accidentally clogging your pipes. Whip up your famed homemade cannoli shells, fill 'em, apply the FryAway, and clean your pan when you're done. FryAway is a US-based small business specializing in planet-friendly cooking waste solutions. Promising review: "I will always keep this stocked in my house! My husband sent me a TikTok, I know I know, and I thought it couldn't hurt to try it out. I loved after the first night! I could easily remove the hardened oil and throw it out." — Roberta Get it from Amazon for $9.97 . 11. Extra long oven mitts , so when you reach into your oven to remove the incredible-smelling turkey you've been cooking for hours, you won't risk burning your arms in the process. Promising review: "I absolutely love these oven mitts! It's one of those kitchen items that are a MUST, but always put off purchasing. I had a criteria of what I wanted in mitts and found them. The mitts do everything they say they do, and that's keeping my hands and arms safe. I highly recommend them." — Amazon Customer Get them from Amazon for $21.99 (available in six colors). 12. A cleverly designed rechargeable electric candle lighter with a flexible neck to light every candle in your house to create the *perfect* ambiance without concern you'll run out of lighter fluid. Promising review: "I cook outside, and lighting a fire during wet and windy weather was a real pain. This lighter was a game changer! As long as the material is dry, this lighter will light regularly, consistently, and easily. Plus, it’s rechargeable! Love it!" — Sandra Get it from Amazon for $9.99+ (available in seven colors and as a two-pack). 13. Pastel "unbreakable" deep plates you can use to serve up your festive feast without fear. No worries if your *very* enthusiastic cousin jumps out of their seat during the Lions/Cowboys Thanksgiving game and forgets they had a plate in their lap. They're also dishwasher-safe and microwave-safe for up to three minutes! Promising review : "These are microwaveable and light to carry. Love the colors. Wish they were available in one color only, but I can’t complain. I primarily bought these for microwave purposes. But can be used for salads, hot soup, etc. Also it’s an in-between size like a medium. Just right for me." — M. Zolnosky Get a set of four from Amazon for $8.95 (also available as bowls !). 14. And a set of matching "unbreakable" rainbow glasses so everyone can sip on their fave holiday bev and you won't have to worry for a second about the moment someone inevitably drops their cup. It'll be way easier to clean up a spilled drink than a pile of glass, that's for sure. Promising review: "OK, so my favorite color is 'rainbow,' and I loved these little glasses the minute I saw them. They hold eight ounces easily without spilling a drop . I've washed them in the dishwasher many times, and they are still bright and shiny. My husband even likes them. I'm sure kids would find them just the right size and easy to use as well. Very durable." — Kameme Get a set of four from Amazon for $14.39 . 15. An instant-read digital thermometer , so you'll never have to guess "is my turkey cooked?" again. You can whip up a delicious meal without worrying about accidentally poisoning your guests. Promising review: "Ordered this about seven months ago. It works great for an instant read of a food's internal temperature. We use it all the time to check mostly meats, roast chicken, chicken breast, steak, pork roast, pork chops, salmon, etc. We want to make sure our food is cooked thoroughly to a safe minimum internal temperature so that nobody gets sick. With this, you don't have to overcook the food to be sure it's done. You can take it off the heat or out of the oven as soon as it gets to temp. This can be switched into Celsius or Fahrenheit." — Kathleen Get it from Amazon for $8.79 (clip the coupon on the product page to save 15%). 16. A pet hair remover with a unique patented brush design that'll let you invite guests to sit down without fear of them being covered head-to-toe in your dog's hair. ChomChom is a small business! You can also snag a mini version for on-the-go hair removal emergencies. BuzzFeed editor Jenae Sitzes adores this product: "I've been using the ChomChom for quite a while now, but I took the photos above literally just now to show just how quick, easy, and effective this roller is. It took 10 seconds to rid my velvet couch ottoman (yes, velvet...a terrible cat owner choice, I know) of the hair my two gray kitties are constantly leaving everywhere. It takes a bit of practice to get the hang of using this roller — at first, I thought you only brushed down in one direction, and was confused why it wasn't picking up hair. It's important to do a push-and-pull brushing in *both* directions so it actually pulls the hair inside , which does require you to apply a bit of pressure. Afterward, you'll just dump out the hair that's been trapped inside. The ChomChom is best for large flat surfaces like couches and beds. Get it from Amazon for $19.99 (available in two colors). 17. And a pet stain and odor remover , so when your dog nephew gets a little too excited to be on vacation at your house for the holidays and decides to pee all over your rug, it's sort of OK. Promising review: "This is one product that really delivers. It was put to the test when our pup had several bouts of diarrhea on the cream/gray woven wool rug in our bedroom. The stains had several hours to soak in before we discovered them. I’ve posted both before and after photos. Although I had to spray and blot with a towel several times, the stains are virtually gone. The scent of Rocco & Roxie is pleasant and all traces of the nasty smell are gone. If you have an indoor pet, you NEED to buy this stuff. It cleans better than anything I’ve used before." — msgrafix Get it from Amazon for $19.48 . 18. A Bissell multipurpose portable cleaner you'll pat yourself on the back for buying when you see just how much dirt and gunk it pulls out of all the surfaces in your life — use it before *and* after having your guests over for Christmas. Promising review: "This vacuum is amazing. I first heard of it on TikTok, where people were using it to clean their stairs, mattresses, car seats, etc., and from the videos, it already looked amazing. But considering how dirty my dining chair cushions were, I was a little bit apprehensive and skeptical. I purchased the item and used it on my chairs for the first time and the results were SO AMAZING. Best vacuum I've ever used. I even bought a second one!" — Davina Get it from Amazon for $81.49 . 19. A Nespresso Vertuo coffee and espresso maker that'll have your mom's favorite drink ready in minutes — if she's happily caffeinated maybe she won't want to nag you about your menu for the evening. It heats up in 15 seconds and has a 40-ounce water tank so you don't have to fill it every morning. Promising review: "I like iced coffee with high caffeine. This fits the bill perfectly and is a joy to use and drink. My Starbucks monthly bill has come down considerably after buying this unit, and I'm ready to hit the ground running that much sooner in the morning. I especially enjoy the self cleaning feature and the ability to run it for smaller or larger cup sizes. Truly a premium product." — David T. Get it from Amazon for $164.50+ (available in three colors, plus in bundle options with the Aeroccino milk frother). 20. Plus some unique espresso cups if you're really looking to impress your guests when you serve coffee with dessert. Folk Ceramics is a small business. Promising review: "These cups are so great! The outer edges of the cup warm up after brewing coffee, but the temperature is comfortable for the hands. These cups have a unique design and I really enjoy every usage." — Great espresso cups Get a set of two from Amazon for $19.96+ (available in five colors). 21. A microwave bacon cooker that'll help you make up to 1 lb of bacon evenly and quickly, so when your extended family is over for Christmas morning brunch, you'll be able to focus on perfecting your eggs and mimosas instead. It's also dishwasher safe! SCS Direct is a small business! Promising review: "Such a simple concept and works amazingly well! I will never cook bacon any other way again. Made crispy, delicious bacon quickly with little to no zero mess in the microwave. You can fit a whole pound on it at once, but it does take longer to cook. I preferred to cook half a pound at a time for 8 minutes. Easy. Fast. Delicious.No mess. Love this product. " — Allysha Austin Get it from Amazon for $11.99 . 22. Wintry percale bed sheets in a *berry* cute print that'll make your guests feel right at home even if they're staying in your guest room during the holidays. This set from Rifle Paper Co. x The Company Store comes with a flat sheet, a fitted sheet, and two pillowcase shams. I've tried out these sheets in a different print and they've easily become my favorites. They always feel crisp and refreshing but still somehow are soft and cozy. If you're looking for something a little more whimsical they also have a Nutcracker print . Get it from The Company Store for $119+ (available in twin, full, and queen sizing). 23. A set of reusable Gripstic bag sealers , you'll cherish every time you re-open a bag of tortilla chips — no stale surprises here! These sticks clamp over open snack bags and ensure they're resealed super tightly — so if you decide to have a little snacky-snack on Christmas Eve before hosting the next day, you can still put them out for guests without them going stale overnight. Gripstic is a small business that specializes in reusable chip clips. Promising review: "I'm a stickler about stale chips and have always used those little snapping clips. I thought they worked pretty well, but they really don't compare to Gripsticks. The snack that proved this the most was Pirate's Booty. If these are exposed to air for more than three minutes, they turn into styrofoam peanuts . I promise they're just as fresh as when you first open them with Gripsticks. They're going to be my go-to chip clips moving forward. " — Rachel Campbell Get a set of 24 from Amazon for $17.95 (available in five sets). 24. A cord-concealing box to help you at long last banish the hot mess of cables lingering next to your TV setup. If your relatives bring little kids or pets over for the holidays it'll keep them out of harm's way as well. Promising review: "I bought it because I saw a woman on TikTok showcase something similar like this on her page (on how to keep a home tidy), and I was like, I HAD to buy! It’s wonderful! I have ALWAYS hated seeing all the clutter of cords stick out from cord extenders and having this makes my small place look cleaner and organized! I would recommend this for anyone!" — Chidi Get it from Amazon for $24.64+ (available in two sizes and three colors). 25. A robotic vacuum , because you and I both know you don't want to spend an evening trying to clean all the dirt and debris from your floors after you've just catered to guests all afternoon. Kick your feet up, watch the 24-hour replay of A Christmas Story, and let this lil' gadget do its thing. This robotic vacuum can easily move between hard floors and low- to medium-pile carpets/rugs and can pick up all the accumulated dust, dirt, and hair while you go about your day. It has an infrared sensor to avoid knocking into obstacles (like furniture and walls) and drop-sensing tech so it won't fall down stairs and off ledges. And if it starts to run low on battery, it'll just return to its base for a recharge! Reviewers do recommend keeping stray items like socks and cords off the floor before running this. Promising review: "This robot vacuum is incredible! I have three dogs and a cat; this vacuum is a time saver. I run it each day, and it has done an incredible job of keeping pet hair, dirt, and debris picked up in my home. Works well on carpet, hardwood, and tile floors. Wish I had purchased it sooner!" — t. hampton Get it from Amazon for $129.99+ (also available in three other models). 26. A Clorox ToiletWand that you can use and then toss away — say SEE YA' to that gross toilet brush hiding in the corner of your bathroom. If you don't immediately get the urge to clean your toilet the second guests leave I'm not sure we can be friends. I own and cherish this product. It's a dream knowing the "brush" is fresh and hasn't been intimate with the inside of my toilet prior to my picking it up again. This set comes with the wand and 16 refills. Promising review: "The primary reason I decided to purchase the Clorox Toilet Wand was so I could clean under my toilet rims, which I noticed was definitely getting neglected via using the standard toilet brushes to clean. Initially, I was looking for a toilet brush that had the shape needed to actually GET under the rim, and that's how I found out about it. Now that I've used it... I can say without a doubt that I'll never go back to a regular brush. I like the cleanliness of the disposable brushes as opposed to a regular toilet brush. And I especially like that I don't have to purchase a second brush with a shape capable of cleaning under the rim, which not only takes up more space, but also would take more time given I'd have to switch back and forth and apply product. With this, I can just clean the entire pot in less than five minutes with the same tool." — Brittney Nelson Get it from Amazon for $18.99 . 27. A red wine stain remover , so you'll forever be prepared when you inevitably spill vino all over your favorite white shirt, couch, and carpet (typically all in one fell swoop) during the chaos of hosting for the holidays. Wine Away is a small business! Promising review: "I'm sure if I knew more about science and chemistry, I'd understand how this stuff works — but since I don't, I'll just assume that it is MAGIC. If you care at all about your carpet, you need to have a bottle of this on standby. Over the years, we've used it to make numerous wine and red juice stains vanish before our eyes. The effect reminds me of the novelty shop disappearing-ink gag from when I was a kid. Seriously, if you've never seen Wine Away in action, it's worth spilling a little Cabernet on your carpet just so you can see it vanish after a few spritzes. I honestly wouldn't believe how quickly this stuff works had I not seen it countless times with my own eyes." — DarthClem Get it from Amazon for $12.49 . 28. A veggie chopper you can use to dice onions in a flash — save your uncontrollable crying for the next time you watch It's a Wonderful Life. It can also spiralize, slice, and chop! Check out a TikTok of the veggie chopper in action. Also! Fullstar is a small business! Promising reviews: "I use this almost every day. It cuts all kinds of veggies and cleans up easily. It's sharp enough to do baby carrots without much effort. For the price, it is worth it." — Carol Habas Get it from Amazon for $24.86 (available in four colors). 29. A mini 2-quart Crock-Pot that'll be the perfect size for tasty dips (queso, anyone?!) that you can easily keep table side. Snacking without missing a single moment of the holiday fun? Yes, please. The lid and stoneware are dishwasher-safe for easy cleanup! Promising review: "Use this little pot for my cheese dip during football games, and it’s a game changer! Leave it plugged in on low during the game, and it keeps my cheese melted and warm for the entire game! Heats evenly, and I feel comfortable leaving it on while I’m away, not for too long though! Couldn’t recommend more!" — Trina Get it from Amazon for $12.99 . 30. Designated bath towels just for guests that'll ensure they're nice and fluffy that'll make anyone who is lucky enough to shower in your bathroom feel ho ho home for the holidays. Promising review: "Bought these for my guests to use. Lots of positive feedback and they hold up well to frequent washes." — twdj Get a set of four from Amazon for $33.99+ (available in 13 colors). 31. And a bar of festive soap with tiny trees inside as well as a green Adventurine stone that'll bring good vibes to your guest's shower and your bathroom's aesthetic. Crystal Bar Soap is a woman-owned small business that sells vegan and cruelty-free soaps, bath bombs, bath oils, and bath salts. I've personally used their crystal-infused soaps for years and absolutely adore them! This one smells like gardenia and peach, but if you're looking for other scents/festive options you can check out their entire holiday collection . Get it from Crystal Bar soap for $16 . 32. Poo-Pourri toilet spray , so in the event someone is about to get *very* intimate with your bathroom they can spritz this directly into the toilet beforehand and avoid 1. embarrassment and 2. stinking up the your entire home. Not to get *too* detailed about my bathroom situation, but I can assure you this stuff really works. I used to work in the room directly next to the main bathroom in our home, which was not the most fun (as you can imagine). However, when I introduced Poo-Pourri into our home it made a huge difference. You only need one or two sprays directly into your toilet before you *do your business* for it to cover up any unpleasant smells. My husband even walked into the bathroom once and said "it smells so good in here" and I promptly said "AHA! IT'S THE POO-POURRI!" He said "ew" and walked away — but it is proof it really works! Get it from Amazon for $8.49 (available in three seasonal scents). 33. Grandma's Secret , a spot remover that'll ensure you don't have to give serving snacks on your couch a second thought. It'll make blood (!!!) pet stains, oil, paint, and other pesky substances vanish into thin air. Promising review: "This stuff is so amazing. I'm a witness. My 2-year-old baby wrote all over my white leather couch. I tried many different things and nothing worked but Grandma's Secret Spot Remover. I love this stuff." — L. Nix Get it from Amazon for $6.09 . 34. A quilted chenille floor pillow for some cozy extra seating — perfect for when your brother brings their new fling to Christmas Eve without giving you a heads up. 🫠 Plus *how lovely* do they look when stacked like in the review photo above!? Gorgeous! Promising review: "This comes just as pictured and described. It is comfortable and looks luxurious. It's great for floor seating." — AKhan Get it from Amazon for $37.54+ (available in six colors). 35. A Dyson WashG1 wet cleaner — one of their latest innovations that'll be an investment worth making. It magically glides across hard floors and thoroughly removes debris, stains, hair (!!!) and other liquids with just water (though you can add detergent if you'd like). You'll be amazed to see how dirty the water becomes in the tank while you clean! I have this bad boy and lemme tell you — it is worth every single penny. Yes, it's pricey, but my home is primarily tile and wood floors and I have two little kids (who basically love on said floors). It uses microfiber rollers to clean and does so so well you'd think there was some sort of magic involved in the making of it. You don't need to do repeated passes to see results — the water in the bottom tank turned so dark my husband and I were horrified (as we mop and vacuum regularly!). After his first try my husband said, "Goodbye, mop!" It's lightweight, which is a huge perk, and the LCD screen lets you select various hydration levels and tells you how much battery time is left. Personally, my favorite highlight is that even though it is a functioning mop of sorts that uses water to clean my floors don't stay wet for very long at all. You can literally walk over the spots you cleaned moments later! It also cleans itself which is fantastic. Definitely worth the splurge. "We have had this for a few weeks, and it’s really changed our floor game! Just using water, it gets our floors amazingly clean! Easy to use- easy to clean. We have a full house of hard flooring so mopping was always a huge ordeal- that’s why we decided to take a chance on this purchase. We have always been a Dyson house though, so it wasn’t a huge gamble and worth the money!" — SamM Get it from Amazon or Dyson for $699.99. 36. A nesting table with seats that can be pulled out conveniently for guests and pushed back in when you're back to your regularly scheduled programming. The "Hugg" nesting table makes me want to do just that — give this genius table a big ol' squeeze. It comes in three different sizes to fit your needs and, honestly, is such a smart product to have on-hand if you're often hosting guests. Get it from Castlery for $449+ (available in three size configurations, two fabrics, and three woods). 37. And a splurge-worthy Lovesac Sactional couch that'll likely be the last couch you ever purchase — it can be completely configured to your exact preference, comes in so many colors and fabrics, and is oh-so comfy. Most importantly, each cushion can be stripped and cleaned in the washing machine with ease. I upgraded from the couch I had lugged from my apartment to my house to a Lovesac Sactional and all I can say is "wow!" Mine is pictured above (left) before we opened our ottoman piece (which is why a back piece is seemingly missing, as each seat comes with a back piece). Anyways, my husband and I are lucky enough to live near a Lovesac store, so before ordering online we went in and tested out all of our options. The Sactionals are so customizable it's nearly overwhelming trying to make a decision! Like many couches, they come in many types of fabrics and colors, but Lovesac does things differently by offering so many configuration options, tons of storage, various arm styles, different seating depths, and the ability to build speakers directly into the couch (just to name a few things!). We opted for a full sectional style and had storage put in every single seat, which we've been using to store throw blankets and my toddler's extensive stuffed animal collection. I love that if we ever want to redecorate our home we can just re-outfit the couch in a different fabric. And it's SO easy to clean — each piece of fabric can be tossed into the washing machine. To date my sister has two Sactionals (and standard Lovesacs) and my cousin just ordered one as well! Get it from Lovesac for $2,280+ (available in many configurations and styles). Me, prepping to host my family for the holidays: Some reviews have been edited for length and/or clarity.
A guardian is a person or entity appointed by a court to who is responsible for the care and supervision of a protected person, and has the legal right to make decisions for that person, typically due to age (old or young) or disability. Indiana Chief Justice Loretta Rush last week noted the number of vulnerable Hoosiers requiring guardianship or other caretaking services continues to rise, and caring for these individuals by creating a better system is both crucial and timely. "In recent years, it has become clear that further research on issues surrounding guardianship can help Indiana create a more effective system of oversight and supervision by aligning resources and designing a system that is easy to navigate and ensures justice is fairly administered," Rush said. To that end, Rush said the Supreme Court has impaneled an 11-member Indiana Guardianship Oversight Task Force tasked with identifying — no later than Dec. 1, 2025 — best practices, future programming, and policies and procedures to improve Indiana’s guardianship system. The high court order specifically directs the task force to focus on the role of the judicial system and the impact of potential reforms, how technology might bolster adult guardianship functions, issues of guardianship oversight, and potential improvements leading to better outcomes for all stakeholders. Listen now and subscribe: Apple Podcasts | Google Podcasts | Spotify | RSS Feed | SoundStack | All Of Our Podcasts The task force is led by Monroe Circuit Judge Geoffrey Bradley and Tippecanoe Circuit Judge Sean Persin, and includes among its members Porter County Magistrate Ana Osan. Guardianship also has been a concern of state Sen. Mike Bohacek, R-Michiana Shores, who won legislative approval in March to establish a pilot program providing a neutral advocate for intellectually disabled women who give birth to a child. Senate Enrolled Act 16 (2024) requires a court presiding over an adoption hearing in LaPorte, Marshall or Starke counties between July 1, 2024, and July 1, 2026, to appoint a guardian ad litem to represent the interests of the mother if she has intellectual disabilities and a court-appointed guardian. Bohacek admitted the need for a guardian ad litem typically will be an "uncommon occurrence." But he said there are known cases of intellectually disabled women under court-appointed guardianships who are sexually assaulted, get pregnant, give birth and the child immediately is given up for adoption — regardless of the mother's wishes. Having a judge appoint a guardian ad litem to look out for the new mother's interests would at least give her some representation and a more reasonable transition into the adoption process, Bohacek said. The proposal was approved 45-0 in the Senate and 97-0 by the House before being signed into law by Republican Gov. Eric Holcomb.100 percent of evaluable patients for minimal residual disease (MRD) testing achieved MRD negativity in MajesTEC-5 as induction therapy and MajesTEC-4 as maintenance therapy SAN DIEGO , Dec. 8, 2024 /PRNewswire/ -- Johnson & Johnson (NYSE:JNJ) today announced new frontline data featuring TECVAYLI ® (teclistamab-cqyv) from two investigational studies in patients with newly diagnosed multiple myeloma (NDMM) in induction and maintenance settings. The MajesTEC-5 ( Abstract #493 ) and MajesTEC-4 ( Abstract #494 ) studies establish the potential of TECVAYLI ® for use in newly diagnosed patients, with promising efficacy and a tolerable safety profile. These data were highlighted as oral presentations at the 2024 American Society of Hematology (ASH) Annual Meeting. 1,2 Forty-nine patients with transplant-eligible NDMM were treated with TECVAYLI ® in combination with DARZALEX FASPRO ® (daratumumab and hyaluronidase-fihj), lenalidomide and dexamethasone (Tec-DRd) or DARZALEX FASPRO ® , bortezomib, lenalidomide and dexamethasone (Tec-DVRd) as induction therapy in the MajesTEC-5 study. 1 All patients who were evaluated for MRD negativity after cycle 3 of induction therapy achieved MRD negativity (10 -5 ) and maintained through cycle 6. 1 "These data from the MajesTEC-5 study build on the growing body of evidence of TECVAYLI combinations that support the potential combinability of TECVAYLI with other effective therapies, demonstrating high rates of MRD-negative responses for evaluable patients with newly diagnosed multiple myeloma," said Rachel Kobos, M.D., Vice President, Oncology Research & Development, Johnson & Johnson Innovative Medicine. "At Johnson & Johnson, our deep expertise and understanding of multiple myeloma has shaped the regimens we're developing, including our bispecific antibodies in new combinations, and we're committed to exploring the full potential of our therapies to improve outcomes for patients." The safety profiles were manageable and consistent with individual safety profiles. 1 No treatment-emergent adverse events (TEAEs) led to study treatment discontinuation or death; cytokine release syndrome (CRS; Grade 1 or 2) occurred in 65 percent of patients. 1 No patients experienced immune effector cell-associated neurotoxicity syndrome (ICANS). 1 Grade 3/4 TEAEs included lymphopenia (43 percent), neutropenia (57 percent) and infections (35 percent). 1 "There remains opportunity to achieve even deeper and more sustained outcomes for a broader patient population in the frontline setting," said Marc S. Raab , M.D., Heidelberg University Hospital, Germany .* "These data reinforce the potential of TECVAYLI when used in earlier lines and show that TECVAYLI can be leveraged to optimize existing standard regimens in combination." Results from the safety run-in of the Phase 3 MajesTEC-4 study highlighted the potential of TECVAYLI ® to be administered as a maintenance therapy following autologous stem cell transplant (ASCT). 2 MajesTEC-4 is the first study to present data on a B-cell maturation antigen (BCMA) bispecific as monotherapy or combination therapy after ASCT. 2 Low rates of non-hematologic Grade 3/4 TEAEs and discontinuation of treatment due to all TEAEs (5.3 percent) were observed. CRS events were all Grade 1/2, mostly occurring during step-up dosing, and ICANS was not observed. Neutropenia and infections were the most common Grade 3/4 TEAEs. 2 Grade 3/4 neutropenia at 6 months showed a decreased trend in cohorts 2 and 3 with less frequent TECVAYLI ® dosing (cohort 1: 94 percent, cohort 2: 63 percent, cohort 3: 47 percent). 2 A similar trend was observed for all-grade infections (cohort 1: 94 percent; cohort 2: 78 percent; cohort 3: 77 percent). 2 All evaluable patients in cohort 1 who underwent MRD assessment after 12 months of therapy were MRD negative, and 100 percent of evaluable patients assessed in cohorts 2 and 3 were also MRD negative at cycle 6. 2 Further analysis of combination therapies will be evaluated in the Phase 3 MajesTEC-7 study, which is currently enrolling. About MajesTEC-5 Study MajesTEC-5 ( NCT05695508 ) is an ongoing, Phase 2 study of teclistamab and talquetamab, evaluating the safety and efficacy of combination regimens in participants with newly diagnosed transplant eligible multiple myeloma. 3 About MajesTEC-4 Study MajesTEC-4 ( NCT05243797 ) is an ongoing, multicenter, randomized, open-label, Phase 3 study of teclistamab in combination with lenalidomide and teclistamab alone versus lenalidomide alone in participants with newly diagnosed multiple myeloma as maintenance therapy following autologous stem cell transplantation. 4 About MajesTEC-7 Study MajesTEC-7 ( NCT05552222 ) is a Phase 3 randomized study comparing teclistamab in combination with daratumumab SC and lenalidomide (Tec-DR) and talquetamab in combination with daratumumab SC and lenalidomide (Tal-DR) versus daratumumab SC, lenalidomide, and dexamethasone (DRd) in participants with newly diagnosed multiple myeloma who are either ineligible or not intended for autologous stem cell transplant as initial therapy. 5 About TECVAYLI ® TECVAYLI ® (teclistamab-cqyv) received approval from the U.S. FDA in October 2022 as an off-the-shelf (or ready-to-use) antibody that is administered as a subcutaneous treatment for adult patients with relapsed or refractory multiple myeloma (RRMM) who have received at least four prior lines of therapy, including a proteasome inhibitor, an immunomodulatory agent and an anti-CD38 antibody. 6 The European Commission (EC) granted TECVAYLI ® conditional marketing authorization (CMA) in August 2022 as monotherapy for the treatment of adult patients with RRMM who have received at least three prior therapies, including a proteasome inhibitor, an immunomodulatory agent and an anti-CD38 antibody, and have demonstrated disease progression since the last therapy. In August 2023 , the EC granted the approval of a Type II variation application for TECVAYLI ® , providing the option for a reduced dosing frequency of 1.5 mg/kg every two weeks in patients who have achieved a complete response (CR) or better for a minimum of six months. TECVAYLI ® is a first-in-class, bispecific T-cell engager antibody therapy that uses innovative science to activate the immune system by binding to the CD3 receptor expressed on the surface of T-cells and to the B-cell maturation antigen (BCMA) expressed on the surface of multiple myeloma cells and some healthy B-lineage cells. In February 2024 , the U.S. FDA approved the supplemental Biologics License Application (sBLA) for TECVAYLI ® for a reduced dosing frequency of 1.5 mg/kg every two weeks (Q2W) in patients with relapsed or refractory multiple myeloma who have achieved and maintained a CR or better for a minimum of six months. For more information, visit www.TECVAYLI.com . About DARZALEX FASPRO ® and DARZALEX ® DARZALEX FASPRO ® (daratumumab and hyaluronidase-fihj) received U.S. FDA approval in May 2020 and is approved for nine indications in multiple myeloma, four of which are for frontline treatment in newly diagnosed patients who are transplant eligible or ineligible. It is the only subcutaneous CD38-directed antibody approved to treat patients with MM. DARZALEX FASPRO ® is co-formulated with recombinant human hyaluronidase PH20, Halozyme's ENHANZE ® drug delivery technology. DARZALEX ® is the first CD38-directed antibody approved to treat multiple myeloma. DARZALEX ® -based regimens have been used in the treatment of more than 585,000 patients worldwide and more than 239,000 patients in the U.S. alone. In August 2012 , Janssen Biotech, Inc. and Genmab A/S entered a worldwide agreement, which granted Janssen an exclusive license to develop, manufacture and commercialize daratumumab. For more information, visit https://www.darzalexhcp.com. About Multiple Myeloma Multiple myeloma is an incurable blood cancer that affects a type of white blood cell called plasma cells, which are found in the bone marrow. 7 In multiple myeloma, these plasma cells proliferate and spread rapidly and replace normal cells in the bone marrow with tumors. 8 Multiple myeloma is the third most common blood cancer worldwide and remains an incurable disease. 9 In 2024, it was estimated that more than 35,000 people will be diagnosed with multiple myeloma in the U.S. and more than 12,000 people would die from the disease. 10 People living with multiple myeloma have a 5-year survival rate of 59.8 percent. 11 While some people diagnosed with multiple myeloma initially have no symptoms, most patients are diagnosed due to symptoms that can include bone fracture or pain, low red blood cell counts, tiredness, high calcium levels and kidney problems or infections. 12,13 TECVAYLI ® IMPORTANT SAFETY INFORMATION WARNING: CYTOKINE RELEASE SYNDROME and NEUROLOGIC TOXICITY including IMMUNE EFFECTOR CELL- ASSOCIATED NEUROTOXICITY SYNDROME Cytokine release syndrome (CRS), including life-threatening or fatal reactions, can occur in patients receiving TECVAYLI ® . Initiate treatment with TECVAYLI ® step-up dosing schedule to reduce risk of CRS. Withhold TECVAYLI ® until CRS resolves or permanently discontinue based on severity. Neurologic toxicity, including Immune Effector Cell-Associated Neurotoxicity Syndrome (ICANS) and serious and life- threatening reactions, can occur in patients receiving TECVAYLI ® . Monitor patients for signs or symptoms of neurologic toxicity, including ICANS, during treatment. Withhold TECVAYLI ® until neurologic toxicity resolves or permanently discontinue based on severity. TECVAYLI ® is available only through a restricted program called the TECVAYLI ® and TALVEY ® Risk Evaluation and Mitigation Strategy (REMS). INDICATION AND USAGE TECVAYLI ® (teclistamab-cqyv) is a bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager indicated for the treatment of adult patients with relapsed or refractory multiple myeloma who have received at least four prior lines of therapy, including a proteasome inhibitor, an immunomodulatory agent and an anti-CD38 monoclonal antibody. This indication is approved under accelerated approval based on response rate. Continued approval for this indication may be contingent upon verification and description of clinical benefit in confirmatory trial(s). WARNINGS AND PRECAUTIONS Cytokine Release Syndrome - TECVAYLI ® can cause cytokine release syndrome (CRS), including life-threatening or fatal reactions. In the clinical trial, CRS occurred in 72% of patients who received TECVAYLI ® at the recommended dose, with Grade 1 CRS occurring in 50% of patients, Grade 2 in 21%, and Grade 3 in 0.6%. Recurrent CRS occurred in 33% of patients. Most patients experienced CRS following step-up dose 1 (42%), step-up dose 2 (35%), or the initial treatment dose (24%). Less than 3% of patients developed first occurrence of CRS following subsequent doses of TECVAYLI ® . The median time to onset of CRS was 2 (range: 1 to 6) days after the most recent dose with a median duration of 2 (range: 1 to 9) days. Clinical signs and symptoms of CRS included, but were not limited to, fever, hypoxia, chills, hypotension, sinus tachycardia, headache, and elevated liver enzymes (aspartate aminotransferase and alanine aminotransferase elevation). Initiate therapy according to TECVAYLI ® step-up dosing schedule to reduce risk of CRS. Administer pretreatment medications to reduce risk of CRS and monitor patients following administration of TECVAYLI ® accordingly. At the first sign of CRS, immediately evaluate patient for hospitalization. Administer supportive care based on severity and consider further management per current practice guidelines. Withhold or permanently discontinue TECVAYLI ® based on severity. TECVAYLI ® is available only through a restricted program under a REMS. Neurologic Toxicity including ICANS - TECVAYLI ® can cause serious or life-threatening neurologic toxicity, including Immune Effector Cell-Associated Neurotoxicity Syndrome (ICANS). In the clinical trial, neurologic toxicity occurred in 57% of patients who received TECVAYLI ® at the recommended dose, with Grade 3 or 4 neurologic toxicity occurring in 2.4% of patients. The most frequent neurologic toxicities were headache (25%), motor dysfunction (16%), sensory neuropathy (15%), and encephalopathy (13%). With longer follow-up, Grade 4 seizure and fatal Guillain-Barré syndrome (one patient each) occurred in patients who received TECVAYLI ® . In the clinical trial, ICANS was reported in 6% of patients who received TECVAYLI ® at the recommended dose. Recurrent ICANS occurred in 1.8% of patients. Most patients experienced ICANS following step-up dose 1 (1.2%), step-up dose 2 (0.6%), or the initial treatment dose (1.8%). Less than 3% of patients developed first occurrence of ICANS following subsequent doses of TECVAYLI ® . The median time to onset of ICANS was 4 (range: 2 to 8) days after the most recent dose with a median duration of 3 (range: 1 to 20) days. The most frequent clinical manifestations of ICANS reported were confusional state and dysgraphia. The onset of ICANS can be concurrent with CRS, following resolution of CRS, or in the absence of CRS. Monitor patients for signs and symptoms of neurologic toxicity during treatment. At the first sign of neurologic toxicity, including ICANS, immediately evaluate patient and provide supportive therapy based on severity. Withhold or permanently discontinue TECVAYLI ® based on severity per recommendations and consider further management per current practice guidelines. Due to the potential for neurologic toxicity, patients are at risk of depressed level of consciousness. Advise patients to refrain from driving or operating heavy or potentially dangerous machinery during and for 48 hours after completion of TECVAYLI ® step-up dosing schedule and in the event of new onset of any neurologic toxicity symptoms until neurologic toxicity resolves. TECVAYLI ® is available only through a restricted program under a REMS. TECVAYLI ® and TALVEY ® REMS - TECVAYLI ® is available only through a restricted program under a REMS called the TECVAYLI ® and TALVEY ® REMS because of the risks of CRS and neurologic toxicity, including ICANS. Hepatotoxicity - TECVAYLI ® can cause hepatotoxicity, including fatalities. In patients who received TECVAYLI ® at the recommended dose in the clinical trial, there was one fatal case of hepatic failure. Elevated aspartate aminotransferase (AST) occurred in 34% of patients, with Grade 3 or 4 elevations in 1.2%. Elevated alanine aminotransferase (ALT) occurred in 28% of patients, with Grade 3 or 4 elevations in 1.8%. Elevated total bilirubin occurred in 6% of patients with Grade 3 or 4 elevations in 0.6%. Liver enzyme elevation can occur with or without concurrent CRS. Monitor liver enzymes and bilirubin at baseline and during treatment as clinically indicated. Withhold TECVAYLI ® or consider permanent discontinuation of TECVAYLI ® based on severity. Infections - TECVAYLI ® can cause severe, life-threatening, or fatal infections. In patients who received TECVAYLI ® at the recommended dose in the clinical trial, serious infections, including opportunistic infections, occurred in 30% of patients, with Grade 3 or 4 infections in 35%, and fatal infections in 4.2%. Monitor patients for signs and symptoms of infection prior to and during treatment with TECVAYLI ® and treat appropriately. Administer prophylactic antimicrobials according to guidelines. Withhold TECVAYLI ® or consider permanent discontinuation of TECVAYLI ® based on severity. Monitor immunoglobulin levels during treatment with TECVAYLI ® and treat according to guidelines, including infection precautions and antibiotic or antiviral prophylaxis. Neutropenia - TECVAYLI ® can cause neutropenia and febrile neutropenia. In patients who received TECVAYLI ® at the recommended dose in the clinical trial, decreased neutrophils occurred in 84% of patients, with Grade 3 or 4 decreased neutrophils in 56%. Febrile neutropenia occurred in 3% of patients. Monitor complete blood cell counts at baseline and periodically during treatment and provide supportive care per local institutional guidelines. Monitor patients with neutropenia for signs of infection. Withhold TECVAYLI ® based on severity. Hypersensitivity and Other Administration Reactions - TECVAYLI ® can cause both systemic administration-related and local injection-site reactions. Systemic Reactions - In patients who received TECVAYLI ® at the recommended dose in the clinical trial, 1.2% of patients experienced systemic-administration reactions, which included Grade 1 recurrent pyrexia and Grade 1 swollen tongue. Local Reactions - In patients who received TECVAYLI ® at the recommended dose in the clinical trial, injection-site reactions occurred in 35% of patients, with Grade 1 injection-site reactions in 30% and Grade 2 in 4.8%. Withhold TECVAYLI ® or consider permanent discontinuation of TECVAYLI ® based on severity. Embryo-Fetal Toxicity - Based on its mechanism of action, TECVAYLI ® may cause fetal harm when administered to a pregnant woman. Advise pregnant women of the potential risk to the fetus. Advise females of reproductive potential to use effective contraception during treatment with TECVAYLI ® and for 5 months after the last dose. ADVERSE REACTIONS The most common adverse reactions (≥20%) were pyrexia, CRS, musculoskeletal pain, injection site reaction, fatigue, upper respiratory tract infection, nausea, headache, pneumonia, and diarrhea. The most common Grade 3 to 4 laboratory abnormalities (≥20%) were decreased lymphocytes, decreased neutrophils, decreased white blood cells, decreased hemoglobin, and decreased platelets. Please read full Prescribing Information , including Boxed WARNING, for TECVAYLI ® . DARZALEX FASPRO ® INDICATIONS AND IMPORTANT SAFETY INFORMATION INDICATIONS DARZALEX FASPRO ® (daratumumab and hyaluronidase-fihj) is indicated for the treatment of adult patients with multiple myeloma: IMPORTANT SAFETY INFORMATION CONTRAINDICATIONS DARZALEX FASPRO ® is contraindicated in patients with a history of severe hypersensitivity to daratumumab, hyaluronidase, or any of the components of the formulation. WARNINGS AND PRECAUTIONS Hypersensitivity and Other Administration Reactions Both systemic administration-related reactions, including severe or life-threatening reactions, and local injection-site reactions can occur with DARZALEX FASPRO ® . Fatal reactions have been reported with daratumumab-containing products, including DARZALEX FASPRO ® . Systemic Reactions In a pooled safety population of 1249 patients with multiple myeloma (N=1056) or light chain (AL) amyloidosis (N=193) who received DARZALEX FASPRO ® as monotherapy or in combination, 7% of patients experienced a systemic administration-related reaction (Grade 2: 3.2%, Grade 3: 0.7%, Grade 4: 0.1%). Systemic administration-related reactions occurred in 7% of patients with the first injection, 0.2% with the second injection, and cumulatively 1% with subsequent injections. The median time to onset was 2.9 hours (range: 5 minutes to 3.5 days). Of the 165 systemic administration-related reactions that occurred in 93 patients, 144 (87%) occurred on the day of DARZALEX FASPRO ® administration. Delayed systemic administration-related reactions have occurred in 1% of the patients. Severe reactions included hypoxia, dyspnea, hypertension, tachycardia, and ocular adverse reactions, including choroidal effusion, acute myopia, and acute angle closure glaucoma. Other signs and symptoms of systemic administration-related reactions may include respiratory symptoms, such as bronchospasm, nasal congestion, cough, throat irritation, allergic rhinitis, and wheezing, as well as anaphylactic reaction, pyrexia, chest pain, pruritus, chills, vomiting, nausea, hypotension, and blurred vision. Pre-medicate patients with histamine-1 receptor antagonist, acetaminophen, and corticosteroids. Monitor patients for systemic administration-related reactions, especially following the first and second injections. For anaphylactic reaction or life-threatening (Grade 4) administration-related reactions, immediately and permanently discontinue DARZALEX FASPRO ® . Consider administering corticosteroids and other medications after the administration of DARZALEX FASPRO ® depending on dosing regimen and medical history to minimize the risk of delayed (defined as occurring the day after administration) systemic administration-related reactions. Ocular adverse reactions, including acute myopia and narrowing of the anterior chamber angle due to ciliochoroidal effusions with potential for increased intraocular pressure or glaucoma, have occurred with daratumumab-containing products. If ocular symptoms occur, interrupt DARZALEX FASPRO ® and seek immediate ophthalmologic evaluation prior to restarting DARZALEX FASPRO ® . Local Reactions In this pooled safety population, injection-site reactions occurred in 7% of patients, including Grade 2 reactions in 0.8%. The most frequent (>1%) injection-site reaction was injection-site erythema. These local reactions occurred a median of 5 minutes (range: 0 minutes to 6.5 days) after starting administration of DARZALEX FASPRO ® . Monitor for local reactions and consider symptomatic management. Neutropenia Daratumumab may increase neutropenia induced by background therapy. Monitor complete blood cell counts periodically during treatment according to manufacturer's prescribing information for background therapies. Monitor patients with neutropenia for signs of infection. Consider withholding DARZALEX FASPRO ® until recovery of neutrophils. In lower body weight patients receiving DARZALEX FASPRO ® , higher rates of Grade 3-4 neutropenia were observed. Thrombocytopenia Daratumumab may increase thrombocytopenia induced by background therapy. Monitor complete blood cell counts periodically during treatment according to manufacturer's prescribing information for background therapies. Consider withholding DARZALEX FASPRO ® until recovery of platelets. Embryo-Fetal Toxicity Based on the mechanism of action, DARZALEX FASPRO ® can cause fetal harm when administered to a pregnant woman. DARZALEX FASPRO ® may cause depletion of fetal immune cells and decreased bone density. Advise pregnant women of the potential risk to a fetus. Advise females with reproductive potential to use effective contraception during treatment with DARZALEX FASPRO ® and for 3 months after the last dose. The combination of DARZALEX FASPRO ® with lenalidomide, thalidomide, or pomalidomide is contraindicated in pregnant women because lenalidomide, thalidomide, and pomalidomide may cause birth defects and death of the unborn child. Refer to the lenalidomide, thalidomide, or pomalidomide prescribing information on use during pregnancy. Interference With Serological Testing Daratumumab binds to CD38 on red blood cells (RBCs) and results in a positive indirect antiglobulin test (indirect Coombs test). Daratumumab-mediated positive indirect antiglobulin test may persist for up to 6 months after the last daratumumab administration. Daratumumab bound to RBCs masks detection of antibodies to minor antigens in the patient's serum. The determination of a patient's ABO and Rh blood type are not impacted. Notify blood transfusion centers of this interference with serological testing and inform blood banks that a patient has received DARZALEX FASPRO ® . Type and screen patients prior to starting DARZALEX FASPRO ® . Interference With Determination of Complete Response Daratumumab is a human immunoglobulin G (IgG) kappa monoclonal antibody that can be detected on both the serum protein electrophoresis (SPE) and immunofixation (IFE) assays used for the clinical monitoring of endogenous M-protein. This interference can impact the determination of complete response and of disease progression in some DARZALEX FASPRO ® -treated patients with IgG kappa myeloma protein. ADVERSE REACTIONS In multiple myeloma, the most common adverse reaction (≥20%) with DARZALEX FASPRO ® monotherapy is upper respiratory tract infection. The most common adverse reactions with combination therapy (≥20% for any combination) include fatigue, nausea, diarrhea, dyspnea, insomnia, headache, pyrexia, cough, muscle spasms, back pain, vomiting, hypertension, upper respiratory tract infection, peripheral sensory neuropathy, constipation, pneumonia, and peripheral edema. The most common hematology laboratory abnormalities (≥40%) with DARZALEX FASPRO ® are decreased leukocytes, decreased lymphocytes, decreased neutrophils, decreased platelets, and decreased hemoglobin. Please click here to see the full Prescribing Information for DARZALEX FASPRO ® . About Johnson & Johnson At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/ or at www.innovativemedicine.jnj.com . Follow us at @JanssenUS and @JNJInnovMed . Janssen Research & Development, LLC and Janssen Biotech, Inc. are both Johnson & Johnson companies. Cautions Concerning Forward-Looking Statements This press release contains "forward-looking statements" as defined in the Private Securities Litigation Reform Act of 1995 regarding product development and the potential benefits and treatment impact of TECVAYLI ® (teclistamab-cqyv ) and DARZALEX FASPRO ® (daratumumab and hyaluronidase-fihj). The reader is cautioned not to rely on these forward-looking statements. These statements are based on current expectations of future events. If underlying assumptions prove inaccurate or known or unknown risks or uncertainties materialize, actual results could vary materially from the expectations and projections of Janssen Research & Development, LLC, Janssen Biotech, Inc., and/or Johnson & Johnson. Risks and uncertainties include, but are not limited to: challenges and uncertainties inherent in product research and development, including the uncertainty of clinical success and of obtaining regulatory approvals; uncertainty of commercial success; manufacturing difficulties and delays; competition, including technological advances, new products and patents attained by competitors; challenges to patents; product efficacy or safety concerns resulting in product recalls or regulatory action; changes in behavior and spending patterns of purchasers of health care products and services; changes to applicable laws and regulations, including global health care reforms; and trends toward health care cost containment. A further list and descriptions of these risks, uncertainties and other factors can be found in Johnson & Johnson's Annual Report on Form 10-K for the fiscal year ended December 31, 2023 , including in the sections captioned "Cautionary Note Regarding Forward-Looking Statements" and "Item 1A. Risk Factors," and in Johnson & Johnson's subsequent Quarterly Reports on Form 10-Q and other filings with the Securities and Exchange Commission. Copies of these filings are available online at www.sec.gov , www.jnj.com or on request from Johnson & Johnson. None of Janssen Research & Development, LLC, Janssen Biotech, Inc. nor Johnson & Johnson undertake to update any forward-looking statement as a result of new information or future events or developments. * Marc S. Raab , M.D., has provided consulting, advisory, and speaking services to Johnson & Johnson; he has not been paid for any media work. 1 Raab, Marc, S., et al, 493 Phase 2 Study of Teclistamab-Based Induction Regimens in Patients with Transplant-Eligible (TE) Newly Diagnosed Multiple Myeloma (NDMM): Results from the GMMG-HD10/DSMM-XX (MajesTEC-5) Trial. 2024 American Society of Hematology Annual Meeting. December 2024 . 2 Zamagni, Elena, et al., 494 Phase 3 Study of Teclistamab (Tec) in Combination with Lenalidomide (Len) and Tec Alone Versus Len Alone in Newly Diagnosed Multiple Myeloma (NDMM) As Maintenance Therapy Following Autologous Stem Cell Transplantation (ASCT): Safety Run-in (SRI) Results from the MajesTEC-4/EMN30 Trial. 2024 American Society of Hematology Annual Meeting. December 2024 . 3 GMMG-HD10 / DSMM-XX / 64007957MMY2003, MajesTEC-5 (HD10/DSMMXX). https://clinicaltrials.gov/study/NCT05695508 . Accessed November 2024 . 4 Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation (MajesTEC-4). https://clinicaltrials.gov/study/NCT05243797 . Accessed November 2024 . 5 A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma (MajesTEC-7). https://classic.clinicaltrials.gov/ct2/show/NCT05552222 . Accessed November 2024 . 6 U.S. FDA Approves TECVAYLI ® (teclistamab-cqyv), the First Bispecific T-cell Engager Antibody for the Treatment of Patients with Relapsed or Refractory Multiple Myeloma. https://www.jnj.com/u-s-fda-approves-tecvayli-teclistamab-cqyv-the-first-bispecific-t-cell-engager-antibody-for-the-treatment-of-patients-with-relapsed-or-refractory-multiple-myeloma . Accessed November 2024 . 7 Rajkumar SV. Multiple myeloma: 2020 update on diagnosis, risk-stratification and management. Am J Hematol. 2020;95(5):548-5672020;95(5):548-567. http://www.ncbi.nlm.nih.gov/pubmed/32212178 8 National Cancer Institute. Plasma Cell Neoplasms. https://www.cancer.gov/types/myeloma/patient/myeloma-treatment-pdq . Accessed November 2024 . 9 City of Hope. Multiple Myeloma: Causes, Symptoms & Treatments. https://www.cancercenter.com/cancer-types/multiple-myeloma . Accessed November 2024 . 10 American Cancer Society. Key Statistics About Multiple Myeloma. https://www.cancer.org/cancer/multiple-myeloma/about/key-statistics.html#:~:text=Multiple%20myeloma%20is%20a%20relatively,men%20and%2015%2C370%20in%20women . Accessed November 2024 . 11 SEER Explorer: An interactive website for SEER cancer statistics [Internet]. Surveillance Research Program, National Cancer Institute. https://seer.cancer.gov/explorer/ . Accessed November 2024 . 12 American Cancer Society. What is Multiple Myeloma? https://www.cancer.org/cancer/multiple-myeloma/about/what-is-multiple-myeloma.html . Accessed November 2024 . 13 American Cancer Society. Multiple Myeloma Early Detection, Diagnosis, and Staging. https://www.cancer.org/cancer/types/multiple-myeloma/detection-diagnosis-staging/detection.html . Accessed November 2024 . Media contacts: Sarah Freeman sfreem21@its.jnj.com Christie Corbett ccorbet6@its.jnj.com Investor contact: Lauren Johnson investor-relations@its.jnj.com U.S. Medical Inquiries +1 800 526-7736 View original content to download multimedia: https://www.prnewswire.com/news-releases/tecvayli-teclistamab-cqyv-demonstrates-potential-as-frontline-combination-therapy-for-patients-with-newly-diagnosed-multiple-myeloma-302325575.html SOURCE Johnson & JohnsonZurcher Kantonalbank Zurich Cantonalbank lifted its position in shares of La-Z-Boy Incorporated ( NYSE:LZB – Free Report ) by 9.9% during the 3rd quarter, Holdings Channel reports. The firm owned 11,146 shares of the company’s stock after purchasing an additional 1,008 shares during the quarter. Zurcher Kantonalbank Zurich Cantonalbank’s holdings in La-Z-Boy were worth $478,000 as of its most recent filing with the Securities and Exchange Commission (SEC). Other institutional investors and hedge funds also recently modified their holdings of the company. Assetmark Inc. acquired a new position in La-Z-Boy during the third quarter worth approximately $30,000. Quarry LP boosted its stake in shares of La-Z-Boy by 2,550.0% during the 2nd quarter. Quarry LP now owns 1,378 shares of the company’s stock worth $51,000 after acquiring an additional 1,326 shares during the period. Canada Pension Plan Investment Board acquired a new position in shares of La-Z-Boy during the 2nd quarter worth approximately $63,000. Innealta Capital LLC bought a new stake in La-Z-Boy in the 2nd quarter valued at $69,000. Finally, Quest Partners LLC acquired a new stake in La-Z-Boy during the 2nd quarter valued at $91,000. 99.62% of the stock is owned by institutional investors. La-Z-Boy Stock Down 0.2 % La-Z-Boy stock opened at $44.72 on Friday. La-Z-Boy Incorporated has a twelve month low of $32.00 and a twelve month high of $46.35. The stock has a market cap of $1.86 billion, a P/E ratio of 15.47 and a beta of 1.34. The company’s 50-day moving average price is $41.78 and its two-hundred day moving average price is $40.40. La-Z-Boy Increases Dividend Wall Street Analyst Weigh In Separately, Sidoti downgraded shares of La-Z-Boy from a “buy” rating to a “neutral” rating and set a $43.00 price objective on the stock. in a report on Wednesday, August 21st. Get Our Latest Analysis on La-Z-Boy About La-Z-Boy ( Free Report ) La-Z-Boy Incorporated manufactures, markets, imports, exports, distributes, and retails upholstery furniture products, accessories, and casegoods furniture products in the United States, Canada, and internationally. It operates through Wholesale, Retail, Corporate and Other segments. The Wholesale segment manufactures, and imports upholstered furniture, such as recliners and motion furniture, sofas, loveseats, chairs, sectionals, modulars, ottomans, and sleeper sofas; and imports, distributes, and retails casegoods (wood) furniture, including occasional pieces, bedroom sets, dining room sets, entertainment centers, and occasional pieces. Recommended Stories Want to see what other hedge funds are holding LZB? Visit HoldingsChannel.com to get the latest 13F filings and insider trades for La-Z-Boy Incorporated ( NYSE:LZB – Free Report ). Receive News & Ratings for La-Z-Boy Daily - Enter your email address below to receive a concise daily summary of the latest news and analysts' ratings for La-Z-Boy and related companies with MarketBeat.com's FREE daily email newsletter .
Butterball Faces Boycott Calls Amid Turkey Sex Abuse AllegationsTottenham succumbed to a disappointing 4-3 defeat at their home ground against London rivals, Chelsea , despite taking a two-goal advantage 11 minutes into the clash. The Athletic jouranlist, Colin Millar has taken to social media to express his concerns about the side's, and specifically the manager's, inability to adapt based on game situations. There have been numerous occasions just this term in which Spurs have taken leads and lost them due to poor game management, including the 3-2 loss to Brighton earlier this season, and the draws to Roma and Fulham more recently. In addition, several worrying defeats to the likes of Ipswich Town and Bournemouth have further worried supporters, who are beginning to grow frustrated with a lack of consistency. Millar: Postecoglou Has a 'Serious Flaw' Speaking to X (formerly Twitter), Millar shared an "extraordinary" statistic, detailing that Spurs had lost a total of 19 games in 40 Premier League matches, citing stubbornness as a key reason. In fact, the last time the two London-based outfits met at this stadium, it was no short of an absolute mess. Despite incurring two red cards, Postecoglou remained adamant with his desired style of play, maintaning a high line with just nine men against the Chelsea attack. The game unsurprisingly ended 4-1 to Chelsea, and the Greek-Australian custodian's adventurous approach was subject to controversy, with many noting that such obstinance may be costly going forward. Indeed, in the same fixture this season, it was some similar adamance which inevitably saw Tottenham lose out on a vital three points. Despite sustaining a two-goal lead very early on, Spurs were unable to control the game, and allowed Chelsea numerous opportunities to turn the game around. Ange Postecoglou's Managerial Record at Tottenham Matches 63 Wins 32 Draws 9 Losses 22 Points per match 1.67 Firm questions are now being asked of Postecoglou's position as manager, as this repeated theme is still yet to be addressed. Pundit, Jamie O'Hara has already gone as far as to call for the sacking of the Tottenham boss , and if such performances continue, other supporters are likely to continue piling on the pressure from the outside. Fans are growing increasingly frustrated of Tottenham's abysmal lack of control of matches. Statistics courtesy of Transfermarkt.com - Correct as of 08/12/2024
NVIDIA Co. (NASDAQ:NVDA) Stake Increased by Custom Index Systems LLC
Pastor Enoch Adeboye has asked Christians to rely on the wisdom of God in doing whatever they want to do in life In his 'Open Heaven' message on Monday, December 9, 2024, Adeboye threw light on 1 Corinthians 1:25-29, the 'Bible reading' for the day The Redeemed Christian Church of God's general overseer shared a prayer point for divine discernment CHECK OUT: Learn at Your Own Pace! Our Flexible Online Course allows you to fit copywriting skills development around your busy schedule. Enroll Now! Legit.ng journalist Ridwan Adeola Yusuf has over 9 years of experience covering religious affairs. Mowe, Ogun state - Pastor Enoch Adeboye, the general overseer of the Redeemed Christian Church of God (RCCG), has released the Open Heaven Daily Devotional for Monday, December 9, 2024. Legit.ng reports that according to RCCG members, the Open Heavens Devotional by Pastor Adeboye is a guide to close fellowship with God in spirit. Christians who intend to boost their spiritual life read and study it anytime anywhere, the church's members say. Read also “N63m fuel in 7 weeks”: RCCG provides free bus service for Nigerians, Leke Adeboye shares details The RCCG leader reportedly authored it through the inspiration of the Holy Spirit. PAY ATTENTION: Legit.ng Needs Your Help! Take our Survey Now and See Improvements at LEGIT.NG Tomorrow In his message for Monday, December 9, 2024, Pastor Adeboye asked his followers to apply Godly wisdom in their affairs. He urged them to do away with "worldly wisdom". Per a video on Ark of God TV , Pastor Adeboye said: "Wisdom strengtheneth the wise more than ten mighty men which are in the city - according to Ecclesiastes 7:19. "The scripture above tells us that a wise man can be stronger than ten mighty men put together. Therefore, one can say that having wisdom is a very good thing." Furthermore, Adeboye advised that wisdom should be based on the word of God, else, 'a time is coming when people who seek and apply worldly wisdom in their activities will hide their faces in shame'. Open Heaven 9 December 2024: Prayer point Read also Prominent Islamic cleric, Sheikh Muyideen Bello buried in Ibadan, video emerges Father, please give me Your wisdom so I can live a fulfilled life. RCCG provides free bus service for Nigerians Earlier, Legit.ng reported that the RCCG provided 10 buses to shuttle commuters between key routes in Lagos , including 7up, Victoria Island, FESTAC, CMS, Ikorodu and Mowe in Ogun state. Explaining that it is the church's way of easing financial burden on Nigerians, Pastor Leke Adeboye said the buses were accessed by everyone, regardless of religion or social status. PAY ATTENTION : Legit.ng Needs Your Opinion! That's your chance to change your favourite news media. Fill in a short questionnaire Source: Legit.ngWith technical prowess and considerable style, Marta danced around two sliding defenders, outwitted a goalkeeper and calmly scored as another player rushed forward in desperation to stop her. It was more Marta Magic. That goal last weekend helped propel the Orlando Pride into Saturday's National Women's Soccer League championship game against the Washington Spirit. Barbra Banda also scored in the Pride's 3-2 semifinal victory over the Kansas City Current . While Banda has had an incredible first season with the Pride, captain Marta has been the talisman that has helped lead the team in its remarkable turnaround this year. The last time the Pride were in the NWSL playoffs was in 2017 — Marta's first year with the club. But this season they nearly went undefeated, going 23 games without a loss to start the season before losing 2-0 to the Portland Thorns with just two regular-season games left. “I think because of the way that we did it, during this season, from beginning to now, it’s something very special that I’ve never had before with any other club that I’ve played for," Marta said. "Plus year by year, we see in America, strong competition. This is the best league in the world. And you never know what’s going to happen, and it’s hard to keep winning the games, being in the first place almost like the whole season. That’s why it’s really different and so special.” Marta’s goal was the latest gasp-inducing moment in a stellar career filled with them. Known by just her first name, the 38-year-old is a six-time FIFA world player of the year. "Let's see if tomorrow I can do something similar — or even better," Marta said on Friday. Her teammate Kylie Strom chimed in: “That was the greatest goal I've ever witnessed, hands down." Appropriate. Earlier this year, FIFA announced that the best goal in women's soccer each year would earn the Marta Award. In a lighthearted moment the day before the title match, Marta was asked if she thought it was possible she might give the award to herself. “You guys need to decide, because who votes for the best goal in the year? It’s you. It’s the people in the public. So it should be really interesting, like Marta’s Award goes to Marta!” she said with a laugh. Marta has played in six World Cups for Brazil and played this summer in her sixth Olympics, winning a silver medal after falling in the final to the United States . She previously said this would be her final year with the national team. But since then Brazil was named the host of the 2027 Women's World Cup. "I had a conversation with my coach, the national team coach, and I was really clear about playing in 2027. I told him it’s not my goal anymore,” she said. “But I’m always available to help the national team. And if they think I still can do something during this preparation for the World Cup, yeah, I would be happy to help them." Marta's club career started in Brazil when she was just 16. She has also played in Sweden and in the U.S. professional women's leagues that came before the NWSL. With nine regular-season goals, Marta has had one of her best seasons since she joined the Pride. “I can never pick a side, I never pick favorites — but I love to see this for Marta," U.S. coach Emma Hayes said. “Marta is someone we all like, admire and are grateful for. And that goal was just like prime Marta at her best. And so grateful for and thankful for her that she got the opportunity with another game with her team.” The Pride went 18-2-6 this season, clinching the NWSL Shield for the first trophy in club history. Orlando also set a record with 60 regular-season points to finish atop the standings. “We are sitting top of the table, but I think there still are a lot of doubters. I think there’s people out there who say, maybe this was a one-off season,” Strom said. “But we’re here to prove them all wrong. So I think we do carry a bit of that underdog mentality still with us.” The second-seeded Spirit advanced to the title match at Kansas City's CPKC Stadium last weekend on a penalty shootout after a 1-1 draw against defending champions Gotham FC. The Spirit's roster includes Trinity Rodman, a standout forward who formed the so-called “Triple Espresso” trio with Mallory Swanson and Sophia Smith for the United States at the Olympics. ___ AP soccer: https://apnews.com/hub/soccer