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In a significant breakthrough, Uttar Pradesh Special Task Force (STF) has arrested two more people involved in the question paper leak of UPPSC Review Officer/Assistant Review Officer (RO/ARO) (Preliminary) Exam 2023, which was conducted on February 11 of this year, it said. The arrested men were identified as Rajneesh Kumar from Azamgarh and Dharmesh Seth from Prayagraj. The arrests took place on December 22, 2024 in Kanpur and Gorakhpur, according to STF. While Kumar was detained in Gorakhpur, Seth was apprehended at Har Sahai Jagdamba College in Kanpur. The leak was first detected when the question paper went viral on social media before the exam. This led to the state government cancelling the examination and asking the STF to investigate the matter. A case was registered at the Civil Lines police station in Prayagraj. The STF probe revealed that the accused had received the question paper from Sandeep Pandey, who had arranged for the exam material to be delivered in Bhopal. Sandeep Pandey, along with several accomplices, had reportedly sold the paper for ₹ 12-15 lakh. Pandey and his associates were arrested earlier in June. The arrested suspects face charges under multiple sections of the IPC, including cheating, forgery, and conspiracy, as well as violations of the Uttar Pradesh Public Examination Act. Further legal proceedings are underway.THE Eliseo Group has called on the National Government to honour its commitment and assist them rebuild with the promised support package for the recovery after “Black Wednesday” riots that rocked the nation in January this year. Eliseo Group director Edward Egobia called on the government to fulfil their commitment that it made to supporting business houses who lost properties, business goods and services during the riots. Mr Egobia highlighted that the government has not paid them any money for the loss they suffered during the riots. Mr Egobia said the company lost one of its shops at Hohola to looters in the January riot where about K10 million worth of building materials and goods where lost. “Other shops also suffered minor losses due to property damage. “We lost K10 million worth of stock (goods) and building. He said just like other businesses that were affected the government promised to pay us for the loss but to date, they have not come to honour their commitment. He said government has to honour its commitment and support us the business houses. They must follow their commitment and honour it. “With our own efforts we are rebuilding all our nine shops throughout the National Capital District to continue provide services to our people. Mr Egobia made the comments during the Christmas promotion draw staged by the company in Wagani on Saturday where about K1 million worth of prizes were given away to customers. “It is a massive Christmas promotion for the company since it spent more than K300,000 to K400,000 so far (in two draws) to give back to its customers in the communities. “The company has already drawn its winners for the first two draws, with two lucky women; Diane Kapris and Mildred Ugwayoba claiming the special prize of a double cab Great Wall of Cannon car. The last raffle draw with the final car will be made on January 4, 2025 at Eliseo Makana, 9-Mile Port Moresby.Lebawit Lily Girma | (TNS) Bloomberg News When winter rolls around, travelers predictably turn their attention to beaches. And this year, it’s the destination that comedian Tony Hinchcliffe called “a floating island of garbage in the middle of the ocean” that’s experiencing outsize demand from Americans planning a warm island vacation. Talk about trashing stereotypes. Related Articles Travel | Would you pay $700 a night to sleep under the stars at this Colorado resort? Travel | Thailand’s starring role in ‘The White Lotus’ is about to pay off Travel | 5 under-the-radar travel destinations the UN says you should visit Travel | Gift ideas for people planning their next trip Travel | Lights and decor, réveillon meals make Christmastime special in New Orleans Puerto Rico has recovered overseas visitors (excluding those from Canada and Mexico) faster than any U.S. state or territory — a staggering 85% increase over its 2019 overseas inbound visitor levels as of 2023, according to an October study from the U.S. National Travel and Tourism Office. There are now more daily flights from the U.S. West Coast, and hotel bookings are 6% higher so far in this last quarter of 2024 year-over-year. It’s a trifecta of tourism growth: more visitors, but also longer stays and a higher spend that reached a record $9.8 billion in 2023, boosting small businesses as well as major brands. “We don’t have a slow season in Puerto Rico anymore,” says Brad Dean, chief executive officer at Discover Puerto Rico. Even if they’re not booking, people are dreaming about “La Isla.” By tracking flight searches for trips between November 2024 and February 2025, a measure of “inspirational” demand, tourism intelligence company Mabrian Technologies reports Puerto Rico is up 9% compared with the same period last year and leads Barbados, the Dominican Republic, Jamaica and the Bahamas in the Caribbean proper. Only Costa Rica ranked higher in the wider region. Dean attributes Puerto Rico’s ongoing tourism growth to a strategic effort to reposition the island’s brand as more than a sun-and-sea destination, starting back in 2018. That led to the Live Boricua campaign, which began in 2022 and leaned heavily on culture, history and cuisine and was, Dean says, “a pretty bold departure” in the way Puerto Rico was showcased to travelers. He adds that at least $2 billion in tourism spend is linked to this campaign. “We (also) haven’t shied away from actively embracing the LGBTQ+ community, and that has opened up Puerto Rico to audiences that may not have considered the Caribbean before,” Dean says. Hotels are preparing to meet this growing demand: A number of established boutique properties are undergoing upgrades valued between $4 million and more than $50 million, including Hotel El Convento; La Concha, which will join the Marriott Autograph Collection; Condado Vanderbilt Hotel; and the Wyndham Grand Rio Mar. That’s in addition to ultra-chic options that are coming online in 2025, including the adults-only Alma San Juan, with rooms overlooking Plaza Colón in the heart of Old San Juan, and the five-star Veranó boutique hotel in San Juan’s trendy Santurce neighborhood. The beachfront Ritz-Carlton San Juan in Isla Verde will also be reopening seven years after Hurricane Maria decimated the island. The travel industry’s success is helping boost employment on the island, to the tune of 101,000 leisure and hospitality jobs as of September 2024, a 26% increase over pre-pandemic levels, according to the U.S. Bureau of Labor Statistics. Efforts to promote Puerto Rico’s provinces beyond the San Juan metro area — such as surfing hub Rincón on the west coast, historical Ponce on the south coast and Orocovis for nature and coffee haciendas in the central mountains —have spread the demand to small businesses previously ignored by the travel industry. Take Sheila Osorio, who leads workshops on Afro-Puerto Rican bomba music and dance at Taller Nzambi, in the town of Loíza, 15 miles east of San Juan; or Wanda Otero, founder of cheese-producing company Vaca Negra in Hatillo, an hour’s drive west of Old San Juan, where you can join a cheese-making workshop and indulge in artisanal cheese tastings. “The list of businesses involved in tourism has gone from 650 in 2018 to 6,100, many of which are artists and artisans,” Dean says. While New Yorkers and Miami residents have always been the largest visitor demographic, Dean says more mainland Americans now realize that going to Puerto Rico means passport-free travel to enjoy beaches, as well as opportunities to dine in Michelin-rated restaurants, hike the only rainforest in the U.S. and kayak in a bioluminescent bay. Visitors from Chicago and Dallas, for example, have increased by approximately 40% from July 1, 2023, to June 30, 2024, compared with the same period in 2022-2023, and more travelers are expected from Denver now that United Airlines Holdings Inc. has kicked off its first nonstop service to San Juan, beginning on Oct. 29. Previously, beach destinations that were easy to reach on direct flights from Denver included Mexico, Belize and California, but now Puerto Rico joins that list with a 5.5-hour nonstop route that cuts more than two hours from the next-best option. Given United Airlines’ hub in San Francisco, it could mean more travelers from the Golden State in the near future, too. In December, U.S. airlines will have 3,000 more seats per day to the territory compared with the same period last year, for a total of 84,731 — surpassing even Mexico and the Dominican Republic in air capacity, according to data from aviation analytics firm Cirium. Luis Muñoz Marín International Airport, the island’s primary gateway, is projecting a record volume of 13 million passengers by year’s end — far surpassing the 9.4 million it saw in 2019. As for Hinchcliffe’s “floating island of garbage” line, Dean says it was “a terribly insensitive attempt at humor” that transformed outrage into a marketing silver lining, with an outpouring of positive public sentiment and content on Puerto Rico all over social media. Success, as that old chestnut goes, may be the best revenge. “It was probably the most efficient influencer campaign we’ve ever had,” Dean says, “a groundswell of visitors who posted their photos and videos and said, ‘This is the Puerto Rico that I know.’” ©2024 Bloomberg L.P. Visit bloomberg.com. Distributed by Tribune Content Agency, LLC.
Nicholas Hoult and Bryana Holly Make Red Carpet Debut at “Nosferatu” Premiere After 7 Years TogetherBy HALELUYA HADERO The emergence of generative artificial intelligence tools that allow people to efficiently produce novel and detailed online reviews with almost no work has put merchants , service providers and consumers in uncharted territory, watchdog groups and researchers say. Related Articles National News | The Container Store, buffeted by rough housing market and competition, seeks bankruptcy protection National News | An ex-police officer is convicted of lying about leaks to the Proud Boys leader National News | Crocodile star of ‘Crocodile Dundee’ dies over age 90 National News | 2 US Navy pilots shot down over Red Sea in apparent ‘friendly fire’ incident, US military says National News | Biden gives life in prison to 37 of 40 federal death row inmates before Trump can resume executions Phony reviews have long plagued many popular consumer websites, such as Amazon and Yelp. They are typically traded on private social media groups between fake review brokers and businesses willing to pay. Sometimes, such reviews are initiated by businesses that offer customers incentives such as gift cards for positive feedback. But AI-infused text generation tools, popularized by OpenAI’s ChatGPT , enable fraudsters to produce reviews faster and in greater volume, according to tech industry experts. The deceptive practice, which is illegal in the U.S. , is carried out year-round but becomes a bigger problem for consumers during the holiday shopping season , when many people rely on reviews to help them purchase gifts. Fake reviews are found across a wide range of industries, from e-commerce, lodging and restaurants, to services such as home repairs, medical care and piano lessons. The Transparency Company, a tech company and watchdog group that uses software to detect fake reviews, said it started to see AI-generated reviews show up in large numbers in mid-2023 and they have multiplied ever since. For a report released this month, The Transparency Company analyzed 73 million reviews in three sectors: home, legal and medical services. Nearly 14% of the reviews were likely fake, and the company expressed a “high degree of confidence” that 2.3 million reviews were partly or entirely AI-generated. “It’s just a really, really good tool for these review scammers,” said Maury Blackman, an investor and advisor to tech startups, who reviewed The Transparency Company’s work and is set to lead the organization starting Jan. 1. In August, software company DoubleVerify said it was observing a “significant increase” in mobile phone and smart TV apps with reviews crafted by generative AI. The reviews often were used to deceive customers into installing apps that could hijack devices or run ads constantly, the company said. The following month, the Federal Trade Commission sued the company behind an AI writing tool and content generator called Rytr, accusing it of offering a service that could pollute the marketplace with fraudulent reviews. The FTC, which this year banned the sale or purchase of fake reviews, said some of Rytr’s subscribers used the tool to produce hundreds and perhaps thousands of reviews for garage door repair companies, sellers of “replica” designer handbags and other businesses. Max Spero, CEO of AI detection company Pangram Labs, said the software his company uses has detected with almost certainty that some AI-generated appraisals posted on Amazon bubbled up to the top of review search results because they were so detailed and appeared to be well thought-out. But determining what is fake or not can be challenging. External parties can fall short because they don’t have “access to data signals that indicate patterns of abuse,” Amazon has said. Pangram Labs has done detection for some prominent online sites, which Spero declined to name due to non-disclosure agreements. He said he evaluated Amazon and Yelp independently. Many of the AI-generated comments on Yelp appeared to be posted by individuals who were trying to publish enough reviews to earn an “Elite” badge, which is intended to let users know they should trust the content, Spero said. The badge provides access to exclusive events with local business owners. Fraudsters also want it so their Yelp profiles can look more realistic, said Kay Dean, a former federal criminal investigator who runs a watchdog group called Fake Review Watch. To be sure, just because a review is AI-generated doesn’t necessarily mean its fake. Some consumers might experiment with AI tools to generate content that reflects their genuine sentiments. Some non-native English speakers say they turn to AI to make sure they use accurate language in the reviews they write. “It can help with reviews (and) make it more informative if it comes out of good intentions,” said Michigan State University marketing professor Sherry He, who has researched fake reviews. She says tech platforms should focus on the behavioral patters of bad actors, which prominent platforms already do, instead of discouraging legitimate users from turning to AI tools. Prominent companies are developing policies for how AI-generated content fits into their systems for removing phony or abusive reviews. Some already employ algorithms and investigative teams to detect and take down fake reviews but are giving users some flexibility to use AI. Spokespeople for Amazon and Trustpilot, for example, said they would allow customers to post AI-assisted reviews as long as they reflect their genuine experience. Yelp has taken a more cautious approach, saying its guidelines require reviewers to write their own copy. “With the recent rise in consumer adoption of AI tools, Yelp has significantly invested in methods to better detect and mitigate such content on our platform,” the company said in a statement. The Coalition for Trusted Reviews, which Amazon, Trustpilot, employment review site Glassdoor, and travel sites Tripadvisor, Expedia and Booking.com launched last year, said that even though deceivers may put AI to illicit use, the technology also presents “an opportunity to push back against those who seek to use reviews to mislead others.” “By sharing best practice and raising standards, including developing advanced AI detection systems, we can protect consumers and maintain the integrity of online reviews,” the group said. The FTC’s rule banning fake reviews, which took effect in October, allows the agency to fine businesses and individuals who engage in the practice. Tech companies hosting such reviews are shielded from the penalty because they are not legally liable under U.S. law for the content that outsiders post on their platforms. Tech companies, including Amazon, Yelp and Google, have sued fake review brokers they accuse of peddling counterfeit reviews on their sites. The companies say their technology has blocked or removed a huge swath of suspect reviews and suspicious accounts. However, some experts say they could be doing more. “Their efforts thus far are not nearly enough,” said Dean of Fake Review Watch. “If these tech companies are so committed to eliminating review fraud on their platforms, why is it that I, one individual who works with no automation, can find hundreds or even thousands of fake reviews on any given day?” Consumers can try to spot fake reviews by watching out for a few possible warning signs , according to researchers. Overly enthusiastic or negative reviews are red flags. Jargon that repeats a product’s full name or model number is another potential giveaway. When it comes to AI, research conducted by Balázs Kovács, a Yale professor of organization behavior, has shown that people can’t tell the difference between AI-generated and human-written reviews. Some AI detectors may also be fooled by shorter texts, which are common in online reviews, the study said. However, there are some “AI tells” that online shoppers and service seekers should keep it mind. Panagram Labs says reviews written with AI are typically longer, highly structured and include “empty descriptors,” such as generic phrases and attributes. The writing also tends to include cliches like “the first thing that struck me” and “game-changer.”
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Luigi Mangione, who is accused of shooting and killing UnitedHealthcare CEO Brian Thompson, fought extradition to New York during a hearing in a Pennsylvania court on Dec. 10. During the hearing, Mangione was denied bail—something he has 14 days to challenge—while prosecutors raised concerns about him being a flight risk. Mangione’s attorney, Thomas Dickey, said his client wanted a hearing on extradition and on whether a second-degree murder charge from New York might be eligible for bail. Manhattan District Attorney Alvin Bragg’s office said that it would seek a governor’s warrant to secure Mangione’s extradition. A felony warrant from New York cited Altoona police stating that written admissions to the crime were found in Mangione’s belongings. A law enforcement bulletin obtained by The Associated Press said that Mangione was likely motivated by anger toward health insurance companies. A Pennsylvania police complaint alleged that Mangione committed forgery, carried a firearm without a license, tampered with records or identification, possessed instruments of crime, and falsely identified himself to law enforcement. The law enforcement bulletin said that Mangione described Ted Kaczynski, the “Unabomber,” as a political revolutionary and that Mangione’s targeting of Thompson appeared to be symbolic. It also said Mangione described health care companies as parasitic and wrote about how profits increased while life expectancy didn’t. Mangione’s cousin, Maryland House of Delegates member Nino Mangione, posted a family statement on social media on Dec. 9. “Unfortunately, we cannot comment on news reports regarding Luigi Mangione,” the statement read. “We only know what we have read in the media. Our family is shocked and devastated by Luigi’s arrest. We offer our prayers to the family of Brian Thompson and we ask people to pray for all involved.”With the holiday shopping season in full swing, Bronx District Attorney Darcel Clark is calling on elected officials and business leaders to reassess how cannabis offenses and retail theft are prosecuted, warning that current laws fail to protect Bronx communities. In a Dec. 6 letter addressed to 12 local Business Improvement District (BID) leaders and elected officials, Clark argued that existing laws are too lenient, enabling crimes that harm small businesses. Clark argued that Bronx small businesses are fighting a losing battle against types of crime that pose a serious threat to their livelihood. The current laws “do not provide adequate protection for our community,” she said in the letter. The Bronx Times reached out to several recipients and is awaiting a response. When it comes to cannabis, Clark said the state’s Marijuana Regulation and Taxation Act of 2021 — aimed at reducing mass incarceration that has disproportionately affected Black and brown people — left a loophole that “[makes] it virtually impossible to prosecute any illegal cannabis possession and sale.” The loophole comes from the current law’s use of “pure weight” instead of “aggregate weight” in measuring cannabis. “Aggregate weight” includes the entire amount of cannabis seized by authorities, which could include fillers, as explained by a DA spokesperson. “Pure weight,” which is more difficult to quantify, only measures the amount that contains the high-inducing chemical THC. For instance, a bag of cannabis that includes stems and seeds would combine for the “aggregate weight.” Amid Bronx officials’ efforts to clamp down on illegal smoke shops, prosecuting under the current “pure weight” standard has let too many illegal cannabis dealers off the hook, in Clark’s view. She pointed to two Brooklyn cases dismissed because of the difference in standard and said she anticipates that the same will happen in the Bronx. Current laws may need to be tweaked to ensure that cannabis seized from unlicensed shops can be prosecuted, she said. ‘Collateral consequences’ Clark said retail theft is another “significant problem” because too many offenders are released and go on to commit more crimes. While 2020 reforms to bail and discovery laws were well-intended at righting some past wrongs in the criminal justice system, some had “collateral consequences,” said Clark. “Whether it’s the result of judges choosing not to set bail for offenses that involve harm to property, or because of the timeline and volume of discovery, retail theft is still a real problem,” said Clark. The DA’s letter said that hardworking local entrepreneurs are unfairly threatened by these issues and that she looks forward to “These business owners pay high rents, work long hours, and struggle to remain economically viable due in large part to illegal activities in surrounding areas,” said Clark. Reach Emily Swanson at eswanson@schnepsmedia.com or (646) 717-0015. For more coverage, follow us on Twitter, Facebook and Instagram @bronxtimes
Tiruppur district is at the forefront in mobilising relief materials for people displaced by Fengal cyclone in Villupuram district. Over the last few days, Tiruppur district administration has despatched over 9,000 boxes of daily provisions, each containing five kg rice, one kg sugar, 500 grams packets of dal, rava and wheat flour, and 100 grams packets of turmeric powder, chilli powder, sambar powder, rasam powder and tea. Several volunteers have been engaged in packing the materials stocked in a marriage hall. The provisions were sent in 17 load vans. Public contributions have been coming in cash and kind from various quarters including individual philanthropists, service organisations, industry associations and more consignments are to be despatched, official sources said. Published - December 07, 2024 08:07 pm IST Copy link Email Facebook Twitter Telegram LinkedIn WhatsApp Reddit
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What's New Texas has announced a lawsuit this week against the National Collegiate Athletic Association (NCAA) seeking to prohibit transgender athletes from competing in women's sports. Texas Attorney General Ken Paxton argues that allowing such participation misleads and deceives fans. Why It Matters Filed in a state district court in Lubbock, the lawsuit announced Sunday alleges that the NCAA's policies permitting transgender athletes in women's sports violate the Texas Deceptive Trade Practices Act. The law is intended to protect consumers from false advertising or deceptive practices, which the suit claims applies to the promotion of women's sports that may include transgender participants. The Texas lawsuit marks the latest effort by conservative lawmakers to challenge the participation of transgender athletes and pressure the NCAA to implement a ban. President-elect Donald Trump has expressed support for such measures, stating his intent to bar transgender athletes from competing. The lawsuit calls for an injunction to bar the NCAA from permitting transgender athletes to compete in women's sports within Texas or in events involving Texas programs. Alternatively, it asks the court to mandate that the NCAA cease labeling such events as "women's" sports if transgender athletes are allowed to participate. What To Know Paxton, in a statement, appeared to allude to the recent controversy surrounding San Jose State women's volleyball. This season, several teams forfeited matches against the Spartans, citing the presence of a transgender player on the roster. Last month, a federal court declined to bar the school from participating in the Mountain West Conference championship. The Associated Press has chosen not to name the player, as she has not publicly addressed her gender identity and declined an interview request through school representatives. The NCAA does not collect specific data on transgender athletes among its 544,000 competitors across 19,000 teams nationwide. Earlier this month, NCAA President Charlie Baker testified before Congress , stating that he was aware of fewer than 10 active NCAA athletes identifying as transgender. Since 2010, the NCAA has required transgender athletes assigned male at birth to undergo at least one year of testosterone suppression therapy before becoming eligible to compete on women's teams. Transgender athletes assigned female at birth who transitioned to male are permitted to compete on men's teams. However, those who undergo testosterone treatment are barred from competing on women's teams. Athletes must adhere to their sport's specific requirements for documented testosterone levels with compliance monitored at various points throughout the season. In 2022, the NCAA updated its policy to align with national sports governing bodies. Under the revised framework, if a sport's governing body lacks a transgender athlete policy, the rules default to those set by the sport's international federation. In the absence of an international policy, previously established Olympic criteria are applied. What People Are Saying "When people watch a women's volleyball game, for example, they expect to see women playing against other women, not biological males pretending to be something they are not," Paxton said in a statement . "Radical 'gender theory' has no place in college sports." Paxton accused the NCAA of "intentionally and knowingly jeopardizing the safety and wellbeing of women" by effectively transforming women's sports into "co-ed competitions." In a statement on Monday, the NCAA said : "College sports are the premier stage for women's sports in America, and while the NCAA does not comment on pending litigation, the Association and its members will continue to promote Title IX, make unprecedented investments in women's sports and ensure fair competition in all NCAA championships." Brooke Slusser , co-captain of the San Jose State volleyball team and one of the players who sued the Mountain West Conference over her teammate's participation, expressed support for the Texas lawsuit. "Hey NCAA, just in case you haven't realized yet this fight will just keep getting harder for you until you make a change!," Slusser wrote in a post on social media . What's Next It's currently unclear how the NCAA will respond to the lawsuit specifically. This article includes reporting from T he Associated Press.Pokhara [Nepal], December 23 (ANI): Former Nepali Home Minister and Chairman of Rastriya Swatantra Party- Rabi Lamichhane's post as Member of Parliament has been suspended, the Federal Parliament Secretariat announced on Monday. Issuing a notice, the General Secretary of the Parliament Secretariat, Padma Prasad Pandey announced Lamichhane's MP position has been suspended. The Kaski District Attorney on Sunday had filed a case including money laundering. Also Read | Sheikh Hasina Extradition: Bangladesh Requests India To Extradite Former Prime Minister; New Delhi Confirms Communication. Lamichhane has been suspended from the post of lawmaker according to Section 27 of the Asset (Money) Laundering Prevention Act, 2008. "Any official or staff of any organized institution established under the prevailing laws or civil servant shall be deemed to be automatically suspended for a period he/she is detained as per this Act or until the case filed against him/her pursuant to Section 22 is settled," states Section 27 of the Act in Nepal's constitution. Also Read | Brian Thompson Murder Case: Luigi Mangione Pleads Not Guilty to State Murder, Other Charges in UnitedHealthcare CEO’s Death. The former TV anchor who rose to political fame and got elected twice from Chitwan Constituency Number 2, is facing charges including money laundering, organized crime, and cooperative fraud. The cases have led to questions about his political future as a lawmaker. Under the Prevention of Money Laundering Act, 2007 (as amended), "any individual holding a public office, such as a lawmaker, who faces a money laundering charge, is automatically suspended from their position until the case is resolved." Section (27) of the Act clearly outlines that a public office-holder detained under this law will be suspended for the duration of their detention and until the case is disposed of. If the court decides to remand Lamichhane in custody, Lamichhane's parliamentary status will be suspended, marking the second time he has faced such a situation. Lamichhane was arrested on October 18 in connection with a separate savings fraud case involving Pokhara's Suryadarshan Cooperative Society. He has been in police custody in Kaski ever since. (ANI) (This is an unedited and auto-generated story from Syndicated News feed, LatestLY Staff may not have modified or edited the content body)SAN ANTONIO (AP) — Davion Bailey had 19 points in Incarnate Word's 65-53 win against East Texas A&M on Saturday. Bailey had four steals for the Cardinals (5-4, 1-1 Southland Conference). Dylan Hayman went 5 of 11 from the field (1 for 3 from 3-point range) to add 11 points. Jalin Anderson had nine points and shot 2 of 9 from the field, including 0 for 3 from 3-point range, and went 5 for 7 from the line. The Lions (1-9, 0-2) were led in scoring by Scooter Williams Jr., who finished with 10 points. Mykol Sanchez-Vega added nine points for East Texas A&M. Josh Taylor finished with eight points. The Lions prolonged their losing streak to six in a row. NEXT UP Incarnate Word next plays Tuesday against Duke on the road, and East Texas A&M hosts South Alabama on Sunday. The Associated Press created this story using technology provided by Data Skrive and data from Sportradar .
On Saturday, the No. 5 Indiana Hoosiers will face off against the No, 2 Ohio State Buckeyes in a highly-anticipated Big Ten matchup. Though this is one of the best games of the Week 13 college football slate, the top-5 contest will not be played under the lights in a primetime slot. Because Fox Sports selected Indiana vs. Ohio State as its "Big Noon Kickoff" game of the week, the game is scheduled to kickoff at noon EST from Ohio Stadium. This decision sparked controversy around the college football world, especially among supporters of the No. 2 Buckeyes. The Ohio State faithful are tired of their marquee matchups taking place at 11 a.m. local time. Despite "Big Noon Kickoff's" decision to make the trip to Columbus on Saturday, ESPN's "College GameDay" also chose Indiana vs. Ohio State as its featured game of the week. When speaking to reporters on Friday, ESPN analyst Kirk Herbstreit subtly referenced Fox Sports' decision to broadcast this top-5 matchup. With ESPN no longer included in the Big Ten's TV deal, Herbstreit doesn't get to call as many Ohio State games as he used to. He's happy that ESPN picked Indiana vs. Ohio State as its featured game, despite Fox Sports' rights to broadcast the contest. Kirby Lee-Imagn Images “Selfishly, I always want to come back to Ohio State to call games. I also want to do Big Ten games. But it's just part of the business that I'm in, and I don't control any of that. I just kind of call the games that they tell me,” Herbstreit said. “So I miss calling Big Ten games. I especially miss calling Ohio State games for obvious reasons. But it's cool that GameDay – I wondered when this split happened, if Game Day would still come to the games that matter on a national level. " "And I think it really says a lot about ESPN and the leadership of College GameDay, we still try to go to the game of the week; no matter who's broadcasting the game, GameDay tries to go to the game," he continued. "And this week, here we are at what we think is the biggest game of the week. And we've done that all year, which is cool.” ESPN's "College GameDay" will begin at 9 a.m. EST on Saturday. Former Ohio State quarterback Justin Fields will join Herbstreit, Nick Saban, Pat McAfee, Desmond Howard, Lee Corso and Rece Davis at the desk as this week's celebrity guest picker. Related: Ohio State Fans Call for Fox Sports Boycott After Indiana Game DecisionHybrid classes coming to Surrey high schools to combat overcrowding'Pole star' of Karnataka politics has disappeared: DK Shivakumar
For travelers, Puerto Rico is a floating island of desirability
Vipers will be aiming to reclaim top spot when they host BUL at Kitende under floodlights on Saturday. The hosts come into the game two points behind NEC who overcame Soltilo Bright Stars on Wednesday and understand that only victory will take them back to the summit. Last season, the two fixtures against BUL ended in defeat for the Venoms costing them a chance to defend their crown for a historic third time in a row. Six-time champions are in buoyant mood after going over ten matches without defeat since tasting loss on match day one to NEC at Lugogo. It is a different scenario for BUL who put up a strong challenge last season and only lost the title on the final day. Abbey Kikomeko’s men have performed abysmally in the last four matches failing to win any despite suffering only one defeat. They find themselves in 11 position with 14 points, closer to the drop zone than the top at this time of the season. However, a rare victory over Vipers at Kitende could see them rise up to 6 place. Match day twelve will conclude on Sunday when KCCA pay a visit to struggling Wakiso Giants at Kabaka Kyabaggu stadium, Wakiso.Evaluating strategic options for iopofosine I 131 a late-stage clinical program with compelling Phase 2 data and a substantial market opportunity Focusing on advancing radiotherapeutic assets including alpha- and Auger-emitting radioconjugates into Phase 1 solid tumor studies FLORHAM PARK, N.J., Dec. 10, 2024 (GLOBE NEWSWIRE) -- Cellectar Biosciences, Inc. (NASDAQ: CLRB), a late-stage clinical biopharmaceutical company focused on the discovery, development and commercialization of drugs for the treatment of cancer, today announces a strategic update on its clinical development programs for its proprietary phospholipid ether drug conjugate platform that delivers a broad array of therapeutic modalities to target cancers. Due to recent communications with the U.S. Food and Drug Administration (FDA, or the Agency) regarding a confirmatory study to support accelerated approval and the regulatory submission for iopofosine I 131, the Company has decided to pursue strategic options for the further development and commercialization of this product candidate. The CLOVER-WaM study was conducted in accordance with earlier FDA communications from an end of Phase 2 meeting and from a meeting in early 2024, during which the Company was informed that positive results for major response rate (MRR) as the primary endpoint could be acceptable to support accelerated approval of iopofosine I 131 as a treatment for Waldenstrom's macroglobulinemia (WM). Based upon a recent Type-C meeting with the FDA, the Company now believes that a submission seeking accelerated approval would need to be based on the MRR data from CLOVER-WaM and enrollment in a randomized, controlled confirmatory study that is designed to generate data on progression-free survival (PFS). "While iopofosine I 131's positive WM data along with the high unmet medical need for these patients support further investment, we have determined that such a program may best be brought to market by a larger organization with greater resources. Importantly, partnering or divesting this program supports our commitment to providing this potentially life-saving drug to the patients who need it as quickly as possible,” stated James Caruso, president and CEO of Cellectar. "We believe iopofosine I 131 represents a compelling opportunity as it has shown strong efficacy and good tolerability based on our clinical studies. Moreover, the commercial work we conducted demonstrates iopofosine I 131's substantial market opportunity based upon the product profile, which includes off-the-shelf global distribution, orphan pricing and existing unmet medical need.” Cellectar remains confident in the potential of its phospholipid ether drug conjugate platform and the targeted radiotherapies in its development pipeline. Iopofosine I 131's clinical success validates the platform's ability to target cancers and Cellectar will leverage its experience to focus on the development of its earlier clinical programs. Specifically, Cellectar will focus on those assets it believes have the highest therapeutic potential and opportunity for value creation. As highlighted by recent acquisitions and collaborations within the radiopharmaceutical sector, precision isotopes like alpha- and Auger-emitters have emerged as the leading therapeutics of interest. Consequently, the Company will now focus its resources on targeting solid tumors by advancing CLR 121225, its actinium-225 based program, and CLR 121125, its iodine-125 Auger-emitting program into the clinic. Cellectar expects to file Investigational New Drug applications in the first half of 2025 for both CLR-121225 and CLR-121125, which will allow the initiation of Phase 1 clinical studies in solid tumor cancers. Both programs have demonstrated robust in vivo activity, tolerability, excellent targeting and uptake in preclinical solid tumor models. The Company believes this approach will provide an expedited timeframe to achieve safety and proof-of-concept data in patients. The Company's strategic reprioritization will impact all departments and result in an immediate reduction in headcount of approximately 60%, which should be complete by the end of the fourth quarter 2024. The Company anticipates that the implementation of the restructuring will extend its cash runway into the third quarter of 2025. "We are being methodical in our efforts to reorganize the company with the goal of conserving cash while maintaining the flexibility to execute immediate priorities and build for long-term growth and value creation. This reorganization is difficult but necessary for the future growth potential of Cellectar,” said Mr. Caruso. "I want to extend my deepest gratitude to our departing employees for their significant contributions to our work and their dedication to making a difference in the lives of patients.” About Cellectar Biosciences, Inc. Cellectar Biosciences is a late-stage clinical biopharmaceutical company focused on the discovery and development of proprietary drugs for the treatment of cancer, independently and through research and development collaborations. The company's core objective is to leverage its proprietary Phospholipid Drug Conjugate TM (PDC) delivery platform to develop the next-generation of cancer cell-targeting treatments, delivering improved efficacy and better safety as a result of fewer off-target effects. The company's product pipeline includes lead asset, iopofosine I 131, a small-molecule PDC designed to provide targeted delivery of iodine-131 (radioisotope), CLR 121225, an actinium-225 based program being targeted to several solid tumors with significant unmet need, such as pancreatic cancer, CLR 121125, an iodine-125 Auger-emitting program targeted in other solid tumors, such as triple negative breast, lung and colorectal, proprietary preclinical PDC chemotherapeutic programs and multiple partnered PDC assets. In addition, iopofosine I 131 is under evaluation in Phase 2b studies for relapsed or refractory multiple myeloma (MM) and central nervous system (CNS) lymphoma, alongside the CLOVER-2 Phase 1b study, targeting pediatric patients with high-grade gliomas, for which Cellectar is eligible to receive a Pediatric Review Voucher from the FDA upon approval. The FDA has also granted iopofosine I 131 Orphan Drug and Fast Track Designations for various cancer indications. New data from the CLOVER-WaM Phase 2 clinical trial were recently presented in an oral presentation at the 66th American Society of Hematology Annual Meeting and Exposition (ASH 2024). For more information, please visit www.cellectar.com or join the conversation by liking and following us on the company's social media channels: Twitter, LinkedIn, and Facebook. Forward-Looking Statement Disclaimer This news release contains forward-looking statements. You can identify these statements by our use of words such as "may," "expect," "believe," "anticipate," "intend," "could," "estimate," "continue," "plans," or their negatives or cognates. These statements are only estimates and predictions and are subject to known and unknown risks and uncertainties that may cause actual future experience and results to differ materially from the statements made. These statements are based on our current beliefs and expectations as to such future outcomes. Drug discovery and development involve a high degree of risk. Factors that might cause such a material difference include, among others, uncertainties related to the ability to raise additional capital, uncertainties related to the disruptions at our sole source supplier of iopofosine, the ability to attract and retain partners for our technologies, the identification of lead compounds, the successful preclinical development thereof, patient enrollment and the completion of clinical studies, the FDA review process and other government regulation, our ability to obtain regulatory exclusivities, the availability of priority review vouchers, our ability to successfully develop and commercialize drug candidates, competition from other pharmaceutical companies, product pricing and third-party reimbursement. A complete description of risks and uncertainties related to our business is contained in our periodic reports filed with the Securities and Exchange Commission including our Form 10-K/A for the year ended December 31, 2023, and our Form 10-Q for the quarter ended September 30, 2024. These forward-looking statements are made only as of the date hereof, and we disclaim any obligation to update any such forward-looking statements. Contacts MEDIA: Christy Maginn Bliss Bio Health 703-297-7194 [email protected] INVESTORS: Anne Marie Fields Precision AQ 212-362-1200 [email protected]