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The gunman, a term often used to describe a prolific goalscorer, is looking to bolster his team's midfield firepower by bringing in a player who can provide creativity, vision, and goal-scoring ability from the center of the pitch. And the Brazilian star in question fits the bill perfectly.
Dazostinag sodium is under clinical development by and currently in Phase I for Non-Small Cell Lung Cancer. According to GlobalData, Phase I drugs for Non-Small Cell Lung Cancer have an 80% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval. Dazostinag sodium overview Dazostinag sodium (TAK-676) is under development for the treatment of advanced or metastatic solid tumors including non-small cell lung cancer, triple-negative breast cancer (TNBC), oropharyngeal cancer, colorectal cancer and head and neck cancer squamous cell carcinoma. The drug candidate is cyclic purine dinucleotide and acts by targeting stimulator of interferon genes (STING/TMEM173). It is a new molecular entity. It is administered via intravenous route. Takeda Pharmaceutical overview (Takeda) is a global pharmaceutical company primarily engaged in the research, development, production, and commercialization of biopharmaceutical products. It provides treatment for inflammatory bowel disease, acid-related diseases, motility disorders and liver diseases; hemophilia and hereditary bleeding disorders; primary immunodeficiency and multifocal motor neuropathy; major depressive disorder and attention-deficit hyperactivity disorder; and its cancer treatment encompasses multiple myeloma, mantle cell lymphoma, non-small cell lung cancer and chronic myeloid leukemia. While the company markets its pharmaceutical products directly, it also collaborates with marketing alliance partners in worldwide. Takeda operates in various countries worldwide, including Japan, the US, Europe, Latin America, Africa, the Middle East, and the Asia Pacific region. Takeda is headquartered in Tokyo, Japan. For a complete picture of Dazostinag sodium’s drug-specific PTSR and LoA scores, This content was updated on 12 April 2024 From Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors. , the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article. GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s .
White House says at least 8 US telecom firms, dozens of nations impacted by China hacking campaignBy SHAWN CHEN Associated Press NEW YORK (AP) — It's time for the holidays, which means robust family conversations and seemingly never-ending courses of food. But for the more tech-savvy among us, the journey home could also mean we'll be called on to provide a backlog of tech support to parents, grandparents and other family members. And with generative AI being used to supercharge some major cyber scams this year, it's also a good time to teach and not just fix. Here are some tips on how to manage your tech encounters this holiday season: Set devices up for automatic updates Whether it's Windows, macOS, iOS or Android, simply keeping your operating system and apps up-to-date will help protect your family's computers and devices against a surprising number of security threats, such as malware, viruses and exploits. Most operating systems, especially those for mobile devices and their app stores, typically have auto-updates turned on by default. Be sure to double-check the device to make sure it has enough storage space to carry out the update. (More on this below.) Keeping apps updated may also reduce the number of "Why isn't this app working?" type of questions from your relatives. Freeing up storage space Chances are someone in your family is going to have a completely full mobile device. So full, in fact, that they can no longer update their phone or tablet without having to purge something first. There are many approaches to freeing up space. Here are a few you can easily take without having to triage data or apps. — Use the cloud to back up media: iPhone users can free up space occupied by songs and pictures by storing them on iCloud. Android users can use the Google Photos app to back up and store their photos on their user space. — Clear browsing data: Each major browser has an option to clear its data cache — cookies, search and download histories, autofill forms, site settings, sign-in data and so on. Over time, these bits take up a significant amount of storage space on mobile devices and home computers. So cleaning caches out periodically helps free up space and, in some cases, improves system performance. What's my password? According to some admittedly unscientific studies, the average person has hundreds of passwords. That's a lot to remember. So as you help your relatives reset some of theirs, you may be tempted to recycle some to keep things simple for them. But that's one of the bad password habits that cybersecurity experts warn against. Instead, try introducing your forgetful family member to a password manager. They're useful tools for simplifying and keeping track of logins. And if you want to impress a more tech-savvy cousin or auntie, you could suggest switching to a more secure digital authentication method: passkeys. Educate your loved ones about the latest scams As scammers find new ways to steal money and personal information, you and your family should be more vigilant about who to trust. Artificial intelligence and other technologies are giving bad actors craftier tools to work with online. A quick way to remember what to do when you think you're getting scammed is to think about the three S's, said Alissa Abdullah, also known as Dr. Jay, Mastercard's deputy chief security officer. "Stay suspicious, stop for a second (and think about it) and stay protected," she said. Simply being aware of typical scams can help, experts say. Robocalls frequently target vulnerable individuals like seniors, people with disabilities, and people with debt. So-called romance scams target lonely and isolated individuals. Quiz scams target those who spend a lot of time on social media. Check our AP guide on the latest scams and what to do when you're victimized. How fast is their WiFi? Home internet speeds are getting faster, so you want to make sure your family members are getting a high-speed connection if they've paid for one. Run a broadband speed test on your home network if they're still rocking an aging modem and router.The outcomes of the ongoing investigations and developments in the tech and automotive sectors will undoubtedly shape the future landscape of these industries, influencing consumer choices, investor confidence, and regulatory trends. As these companies continue to make headlines with their innovations and controversies, one thing remains clear - the scrutiny and expectations on corporate behavior and performance have never been higher.
The Gage County Board of Supervisors denied a special-use permit to build a telecommunications tower northwest of Filley at its meeting Wednesday at the courthouse. The tower was the subject of a lengthy public hearing at the board's Nov. 13 meeting, with members of the public who testified solidly against the project. The vote was 5-2 in favor of a motion to reject the permit, with Supervisors Don Schuller and Dave Swavely voting against the motion. Supervisor Terry Jurgens made the motion to deny the permit, citing the objections raised at the public hearing — a petition against the tower; its impact on nearby residents and businesses; equipment used by Viaero, the company that planned to lease tower; its location; and the company's refusal to meet with residents. He was seconded by Supervisor Emily Haxby. Supervisor Don Schuller admitted it was a tough decision. 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Recap: Here's how Joey Graziadei will win 'Dancing with the Stars' How one Virginia woman persevered through abuse, oppression in Christian 'cult' "Much of (the) people here, and part of this area served, and this location is in my district," he said, "but I'm also here to serve the entire county, and I feel that denying this permit is not in the best interests of the entire county." Schuller acknowledged the concerns of nearby residents and businesses over land values and economic impacts. But he said the concerns were speculation that ignored the positives the project could bring. "It's felt that it's not needed because service is good there now," Schuller said. "Well, this extends beyond just that area, and it will in the future." "I feel like we need to be consistent in approving and disapproving like businesses or infrastructure needs," Schuller said, citing previous tower approvals. "Gage County needs the infrastructure." "I'm concerned that future businesses will not even look at us, because there's too big a risk that they'll get turned down," he added later. "We have Planning and Zoning, we've got regulations, but then we tweak it for each situation, we move the goalposts, and they get turned down." Haxby said it was fair for the county to examine each proposal as it comes in. "This is the first one for tower application I've seen this much opposition for," she said. "As we ... represent the constituents of Gage County, that's kind of what we have to listen to as well." Schuller put the project up against the county's regulations. "'Be compatible with and similar to use permitted in the district.' Well, it is," he said. "'Not to be a matter which should require rezoning of the property,' which it doesn't. 'Not to be detrimental to adjacent property,' that's a matter of opinion. ... 'Not tend to depreciate the value of the surrounding structures or property.' There again, you might have two appraisers that disagree on that. ... 'Not change the character of the district,' I can't say that it changes the character of our district. ... 'Be in accordance with the comprehensive plan.' Well, ... you can read the comprehensive plan and you can make what you want out of it. ..." "That's the beauty of the board," Haxby replied. "We all have different opinions, and in the end, we vote for what's best for the people that we represent." After the meeting, Chris Riha, site acquisition specialist for Industrial Tower West, the company that wants to build the tower, said he didn't know what the company's next step will be. Moving the tower to the east would create an overlap with a tower the company plans to build near Crab Orchard. "I totally respect the opposition," Riha said. "... We did our homework, we followed all the rules and regs and everything, and we're getting turned down for several reasons that the opposition testified. ... "The opposition was civil. I appreciate that." Riha said the request to meet with residents came after the company had completed site studies and spent thousands on an environmental report. "Once you submit the application and spend all the money on two years of getting a survey done, ... a whole bunch of other state, federal applications, you just don't drop a site," he said. Before voting on the Filley permit, the board had voted unanimously for a special-use permit for a telecom tower near Liberty. That permit had the support of the Planning and Zoning Commission and the Liberty Village Board. In other action Wednesday: * Sheriff Millard "Gus" Gustafson presented the annual statistics report for the county jail, courthouse and Sheriff's Office. From October 2023 to September 2024, the Sheriff's Office transported 276 inmates to the courthouse; Gustafson said allowing inmates to appear in court via Zoom has helped reduce that number. * The board approved an interlocal agreement with Saline County for the state's County Bridge Match Program on four box culvert projects. * The board approved giving Vogtscapes an extension on its contract to install box culverts after rain in other areas delayed the work in the county. * Nebraska Extension educator Nicole Stoner introduced Carly Applegarth, the new food, nutrition and health educator, as part of the Extension's update to the board. Reach the writer at rschlotterbeck@beatricedailysun.com . Stay up-to-date on the latest in local and national government and political topics with our newsletter.The lack of consistent attacking threat from the left side has been a cause for worry for Arsenal fans and critics alike. While Bukayo Saka has shown great potential in that position, there have been calls for a more established and experienced player to provide more cutting edge in the final third. The team's performance in terms of expected goals (xG) in open play has raised eyebrows, with Arsenal ranking near the bottom in the Premier League.
Klopp's journey to Liverpool was not without its challenges, but his unwavering optimism and deep understanding of the game have propelled the club to new heights. His keen eye for talent, tactical acumen, and ability to inspire his players have transformed the Reds into a formidable force in European football.The committee explained that the drones were equipped with advanced technology to transmit live footage to a control center on the ground. However, it is believed that external factors, such as nearby radio signals or electromagnetic interference, disrupted the communication signals between the drones and the control center, resulting in the unexpected crash.
In the world of gaming, there are endless possibilities waiting to be explored. Today marks a significant day for all gaming enthusiasts as the highly anticipated soul card game "Play On! Hero of Souls" is officially released! This innovative game combines the strategic elements of card games with the immersive world of fantasy, promising players a thrilling experience like never before.
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Brendan Rodgers praises Celtic and Cameron Carter-Vickers’ mentality