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Lopetegui came into the game under pressure following some poor displays from the Hammers in recent weeks but they earned a hard-fought victory to end the Magpies’ three-game winning spell. Despite a promising opening from the hosts, Tomas Soucek headed West Ham in front before Aaron Wan-Bissaka’s first goal for the club after the break wrapped up victory. Lopetegui was pleased with his side’s display following a “tough match”. He said: “I am happy for the three points and am very happy against a good team like Newcastle, who have good players and a fantastic coach. “I think today was a tough match and we were able to compete as a team. “I think we deserved to win. Today they had many moments in the first half, but I think the second half we deserved to win and we are happy because you have to do these kind of matches against this type of team if you want to overcome them.” Newcastle started brightly and had plenty of chances in the first half especially, but the visitors responded after the break by retaining possession well. The win eases the pressure on Lopetegui, whose West Ham side face Arsenal on Saturday, and he believes the victory is an important feeling for his players. He said: “I think the only thing that is under our control is to play football, to improve, to defend well, to convince the players we are able to do better. “Today we did, but I think the only thing we can do is to do the things that are under our control, not today but every day. “So we had to keep with this mentality, but above all let me say we are happy for the players because they need this kind of feeling as a team to believe that we are able to do well as a team, to put the best for each player of the team.” Newcastle boss Eddie Howe admitted defeat was a missed opportunity for his side. The Magpies missed a series of chances in the first half, including efforts from Joe Willock and Sean Longstaff, before Alexander Isak blasted a chance off target. Anthony Gordon also rolled an effort just wide of the post after the break and Isak headed wide of goal. Three points could have seen Newcastle move into the top six and Howe admitted his side need to learn from the match. “Yes, massive because the league is so tight that a couple of wins and the whole picture looks very different,” Howe said. “We’ll kick ourselves tonight because we knew the opportunity we had, a home game, Monday night, a great moment for us potentially in our season, so we have to learn from that and come back stronger.”

Regime Inaugurates a Biotechnology Company in China that Is One-Hundred Percent CubanOffering patients an injection is more effective than the current care of steroid tablets and cuts the need for further treatment by 30%, according to a study. Benralizumab is a monoclonal antibody that targets specific white blood cells, called eosinophils, to reduce lung inflammation. It is currently used as a repeat treatment for severe asthma at a low dose, but a new clinical trial has found that a higher single dose can be very effective if injected at the time of a flare-up. The findings, published in the Lancet Respiratory Medicine, included 158 people who needed medical attention in A&E for their asthma or COPD attack (COPD is a group of lung conditions that cause breathing difficulties). Patients were given a quick blood test to see what type of attack they were having, with those suffering an “eosinophilic exacerbation” involving eosinophils (a type of white blood cell) being suitable for treatment. Around 50% of asthma attacks are eosinophilic exacerbations, as are 30% of COPD ones, according to the scientists. The clinical trial, led by King’s College London and carried out at Oxford University Hospitals NHS Foundation Trust and Guy’s and St Thomas’ NHS Foundation Trust, saw patients randomly split into three groups. One group received the benralizumab injection and dummy tablets, another received standard care (prednisolone steroids 30mg daily for five days) and a dummy injection, and the third group received both the benralizumab injection and steroids. After 28 days, respiratory symptoms of cough, wheeze, breathlessness and sputum were found to be better in people on benralizumab. And after 90 days, there were four times fewer people in the benralizumab group who failed treatment compared with those receiving steroids. Treatment with the benralizumab injection also took longer to fail, meaning fewer visits to a GP or hospital for patients, researchers said. Furthermore, people also reported a better quality of life on the new regime. Scientists at King’s said steroids can have severe side-effects such as increasing the risk of diabetes and osteoporosis, meaning switching to benralizumab could provide huge benefits. Lead investigator Professor Mona Bafadhel, from King’s, said: “This could be a game-changer for people with asthma and COPD. “Treatment for asthma and COPD exacerbations have not changed in 50 years, despite causing 3.8 million deaths worldwide a year combined. “Benralizumab is a safe and effective drug already used to manage severe asthma. “We’ve used the drug in a different way – at the point of an exacerbation – to show that it’s more effective than steroid tablets, which is the only treatment currently available.” Researchers said benralizumab could also potentially be administered safely at home or in a GP practice, as well as in A&E. First author Dr Sanjay Ramakrishnan, clinical senior lecturer at the University of Western Australia, said: “Our study shows massive promise for asthma and COPD treatment. “COPD is the third leading cause of death worldwide but treatment for the condition is stuck in the 20th century. “We need to provide these patients with life-saving options before their time runs out.” Dr Samantha Walker, director of research and innovation at Asthma and Lung UK, welcomed the findings but said: “It’s appalling that this is the first new treatment for those suffering from asthma and COPD attacks in 50 years, indicating how desperately underfunded lung health research is.” AstraZeneca provided the drug for the study and funded the research, but had no input into trial design, delivery, analysis or interpretation.Farmer's 22 lead Youngstown State over Oakland 66-50

PUNE City doctors successfully performed “bipolar cord occlusion followed by in-utero cord transection” procedure to save a baby in a complex rare case of monoamniotic twins. This procedure is the third case in India involving such two staged interventions in monoamniotic twins, doctors said on Saturday. A 21-week pregnant mother, a nurse from Satara district was diagnosed with monoamniotic twins. Monoamniotic twins are identical twins that share an amniotic sac and placenta and is a rare type of twin pregnancy. Due to one placenta, these babies have a vascular connection called anastomosis and blood flows from one baby to another and vice-versa putting both babies at risk of fatality. The team of doctors at KEM hospital comprised—Dr Manikandan K, fetal surgeon and fetal medicine consultant, fetal medicine expert, Dr Shweta Gugale and gynaecologist Dr Xerxes Coyaji. Also, Shreepad Karhade, head and associate consultant, fetal medicine, Dr Ashwini Jaybhaye and Dr Pooja Pable were part of the team. Dr Gugale said, “One baby was extremely small while the other baby was developing normally. The small one had a depleting blood supply which would eventually stop. But due to the vascular connection, the normally developing baby would start giving its blood to the other one. This would ultimately lead to total pregnancy loss.” As per the doctors, the normally developing baby was also at high risk and without a bipolar cord occlusion procedure on the small co-twin, the chances of survival of the normal twin become very low in such a situation. The team performed a two-stage procedure. In the first step, bipolar forceps were used to coagulate the umbilical cord of the abnormal twin, stopping its blood supply. Later, with fetoscopy-guided laser technology, the doctors cut the cord to prevent further complications like cord entanglement. This results in a sacrifice of the abnormal twin hence increasing the chances of survival of co-twin, they said. The clinical management of these pregnancies is challenging, there is a high risk of unexpected fetal death (up to 15–20%) and or a high risk of brain injury in the surviving co-twin. “The first 24 hours are extremely crucial for the co-twin. A Doppler test post-24-hour observation was normal, and the mother’s follow-up scans indicated a healthy pregnancy,” added, Dr Gugale. Dr Karhade, said, that addressing such rare and complicated cases requires a tertiary setup with a multidisciplinary approach. “With the available state-of-the-art facilities at Hospital for Reproductive Health we have successfully handled 25 high-risk fetal interventions, including this rare case,” he said. Apart from the procedure itself, the most challenging part is counselling the family, they said.None

Montana Grizzlies' season ends with 2nd-round FCS playoffs loss at South Dakota StateAlexander and Boston University secure 80-74 OT win over Albany

SWEET treat fanatics are flocking to three discount stores to get their hands on a new selection of Baileys deserts. Both Baileys Eclairs and Baileys Indulgent Biscuits have been spotted on the shelves this Christmas. Aldi and Home Bargains have stocked up the creamy confectionaries and eagle-eyed shoppers were delighted to find them in Iceland as well. A lot of people adored the creamy-flavoured find, and were gushing in the comment section of the Iceland website. One wrote: "Wow absolutely delicious. "You can taste the Baileys in the very generous cream, will definitely buy again." Another added: "Very nice, lots of Baileys in a small eclair." A third user commented: "Delicious, just the right amount of Baileys cream." However not everyone was impressed. One user posted: "Pleased I didn't pay full price for them. "I wont be buying any for myself for Christmas and will have to decide whether I still give them as gifts or give them to the local church for Christmas raffle - maybe with a very sweet warning attached." Another complained: "Smaller than expected, and with a weird aftertaste. "They don't taste like proper Baileys, more like a cheap imitation." Despite the mixed reviews, shoppers are still keen to give the new Baileys collection a try. The Baileys Indulgent Biscuits are described as buttery but still with a hint of liqueur, and not too overpowering. As the the Baileys Milk Chocolate Creams, they consist a balance of a creamy whisky filling covered in milk chocolate. The mini eclairs have a creamy Baileys flavoured filling in a light pastry, covered with a smooth chocolate coating. These are frozen in a pack of 12 and instructions suggest defrosting them for 30 minutes before tucking in. If you're a sucker for that creamy Irish whiskey liqueur, then there are some sneaky hacks that can save you on splashing out on Baileys this festive season. If you want to save your money for presents, you can always go for a Baileys dupe, which have been described as "almost perfect." If you're prepared to let go of the litre bottle you can purchase the 70cl Ballycastle cream liqueur for £5.79 - just 82p per 100ml. Shoppers have described the product as "lush" and "gorgeous" on Facebook. The Ballycastle product also comes in various flavours, such as the newest addition, which is a luscious Milk Chocolate Clementine version for £7.49. If you fancy giving something new a try, this could save you up to a whopping £16.21 on one bottle of Baileys. For the price of one Baileys bottle from Morrisons or Asda, £22.00, you could nearly buy four bottles of the Ballycastle. However, keep in mind that the ABV of Bailey's is 16 per cent, the Ballycastle booze is 12 per cent. Other supermarkets which offer up their own Baileys dupes include Sainsbury's, Tesco, Morrison's, Asda, Lidl and M&S. Consumer reporter Sam Walker reveals how you can save money on your Christmas shopping Limit the amount of presents - buying presents for all your family and friends can cost a bomb. Instead, why not organise a Secret Santa between your inner circles so you're not having to buy multiple presents. Plan ahead - if you've got the stamina and budget, it's worth buying your Christmas presents for the following year in the January sales. Make sure you shop around for the best deals by using price comparison sites so you're not forking out more than you should though. Buy in Boxing Day sales - some retailers start their main Christmas sales early so you can actually snap up a bargain before December 25. Delivery may cost you a bit more, but it can be worth it if the savings are decent. Shop via outlet stores - you can save loads of money shopping via outlet stores like Amazon Warehouse or Office Offcuts. They work by selling returned or slightly damaged products at a discounted rate, but usually any wear and tear is minorOffering patients an injection is more effective than the current care of steroid tablets and cuts the need for further treatment by 30%, according to a study. Benralizumab is a monoclonal antibody that targets specific white blood cells, called eosinophils, to reduce lung inflammation. It is currently used as a repeat treatment for severe asthma at a low dose, but a new clinical trial has found that a higher single dose can be very effective if injected at the time of a flare-up. The findings, published in the Lancet Respiratory Medicine, included 158 people who needed medical attention in A&E for their asthma or COPD attack (COPD is a group of lung conditions that cause breathing difficulties). Patients were given a quick blood test to see what type of attack they were having, with those suffering an “eosinophilic exacerbation” involving eosinophils (a type of white blood cell) being suitable for treatment. Around 50% of asthma attacks are eosinophilic exacerbations, as are 30% of COPD ones, according to the scientists. The clinical trial, led by King’s College London and carried out at Oxford University Hospitals NHS Foundation Trust and Guy’s and St Thomas’ NHS Foundation Trust, saw patients randomly split into three groups. One group received the benralizumab injection and dummy tablets, another received standard care (prednisolone steroids 30mg daily for five days) and a dummy injection, and the third group received both the benralizumab injection and steroids. After 28 days, respiratory symptoms of cough, wheeze, breathlessness and sputum were found to be better in people on benralizumab. And after 90 days, there were four times fewer people in the benralizumab group who failed treatment compared with those receiving steroids. Treatment with the benralizumab injection also took longer to fail, meaning fewer visits to a GP or hospital for patients, researchers said. Furthermore, people also reported a better quality of life on the new regime. Scientists at King’s said steroids can have severe side-effects such as increasing the risk of diabetes and osteoporosis, meaning switching to benralizumab could provide huge benefits. Lead investigator Professor Mona Bafadhel, from King’s, said: “This could be a game-changer for people with asthma and COPD. “Treatment for asthma and COPD exacerbations have not changed in 50 years, despite causing 3.8 million deaths worldwide a year combined. “Benralizumab is a safe and effective drug already used to manage severe asthma. “We’ve used the drug in a different way – at the point of an exacerbation – to show that it’s more effective than steroid tablets, which is the only treatment currently available.” Researchers said benralizumab could also potentially be administered safely at home or in a GP practice, as well as in A&E. First author Dr Sanjay Ramakrishnan, clinical senior lecturer at the University of Western Australia, said: “Our study shows massive promise for asthma and COPD treatment. “COPD is the third leading cause of death worldwide but treatment for the condition is stuck in the 20th century. “We need to provide these patients with life-saving options before their time runs out.” Dr Samantha Walker, director of research and innovation at Asthma and Lung UK, welcomed the findings but said: “It’s appalling that this is the first new treatment for those suffering from asthma and COPD attacks in 50 years, indicating how desperately underfunded lung health research is.” AstraZeneca provided the drug for the study and funded the research, but had no input into trial design, delivery, analysis or interpretation.Gus Malzahn is leaving UCF to become Florida State's offensive coordinator, AP source says

Gus Malzahn is leaving UCF to become Florida State's offensive coordinator, AP source saysGautam Adani breaks silence on US allegations to say his group is committed to compliance

Independent Senator Fatima Payman has apologised for labelling Pauline Hanson a racist, after several members of the public pointed out that it was not suitable language to describe the One Nation leader. “I am sorry for using that terminology, it was grossly inappropriate and I now realise there is more fitting wording that I should have used,” Payman is believed to have said. Political experts say it was an unfortunate slip-up by Payman who should have known better. “Anyone in politics in this country should know that there is a right way and a wrong way to describe Ms Hanson. Even ‘massive racist’ would have been better than this. That said, she is young; she will learn from this experience,” one observer said. _____

Trump's Controversial Cabinet Choices Amid AllegationsNone

South Korea’s main opposition Democratic Party leader Lee Jae-myung, bottom center, shouts slogans during a news conference with his party members at the National Assembly in Seoul, South Korea, on Saturday. The signs read “Punish the rebellion leader.” Ahn Young-joon/Associated Press SEOUL, South Korea — South Korea’s embattled President Yoon Suk Yeol avoided an opposition-led attempt to impeach him over his short-lived imposition of martial law, as most ruling party lawmakers boycotted a parliamentary vote Saturday to deny a two-thirds majority needed to suspend his presidential powers. The scrapping of the motion is expected to intensify protests calling for Yoon’s ouster and deepen political chaos in South Korea, with a survey suggesting a majority of South Koreans support the president’s impeachment. Yoon’s martial law declaration drew criticism from his own ruling conservative People Power Party, but the party is also determined to oppose Yoon’s impeachment, apparently because it fears losing the presidency to liberals. After the motion fell through, members of the main liberal opposition Democratic Party rallied inside the National Assembly, chanting slogans calling for Yoon’s impeachment or resignation. The party’s floor leader, Park Chan-dae, said it will soon prepare for a new impeachment motion. Opposition parties could submit a new impeachment motion after a new parliamentary session opens next Wednesday. “We’ll surely impeach Yoon Suk Yeol, who is the greatest risk to Republic of Korea,” party leader Lee Jae-myung said. “We’ll surely bring back this country to normal before Christmas Day or year’s end.” Many experts doubt Yoon will be able to serve out his remaining 2 1⁄2 years in office. They say some PPP lawmakers could eventually join opposition parties’ efforts to impeach Yoon if public demands for it grow further. The ruling party risks “further public outrage and national confusion if they don’t find a formula fast for Yoon’s departure,” said Duyeon Kim, a senior analyst at the Center for New American Security in Washington. PPP chair Han Dong-hun said his party will seek Yoon’s “orderly” early exit but didn’t say when he can resign. PROTESTS AGAINST YOON ARE SWELLING On Saturday, tens of thousands of people packed several blocks of roads leading to the National Assembly, waving banners, shouting slogans and dancing. Protesters also gathered in front of PPP’s headquarters near the Assembly, shouting for its lawmakers to vote to impeach Yoon. A smaller crowd of Yoon’s supporters, which still seemed to be in the thousands, rallied elsewhere in Seoul, calling the impeachment attempt unconstitutional. Impeaching Yoon required support from 200 of the National Assembly’s 300 members. The Democratic Party and five other small opposition parties, which filed the motion, have 192 seats combined. But only three lawmakers from PPP participated in the vote. The motion was scrapped without ballot counting because the number of votes didn’t reach 200. National Assembly Speaker Woo Won Shik called the result “very regrettable” and an embarrassing moment for the country’s democracy. If Yoon is impeached, his powers will be suspended until the Constitutional Court decides whether to remove him from office. If he is removed, an election to replace him must take place within 60 days. PRESIDENT APOLOGIZES FOR TURMOIL Earlier Saturday, Yoon issued an apology over the martial law decree, saying he won’t shirk legal or political responsibility for the declaration and promising not to make another attempt to impose it. He said would leave it to his party to chart a course through the country’s political turmoil, “including matters related to my term in office.” “The declaration of this martial law was made out of my desperation. But in the course of its implementation, it caused anxiety and inconveniences to the public. I feel very sorry over that and truly apologize to the people who must have been shocked a lot,” Yoon said. Since taking office in 2022, Yoon has struggled to push his agenda through an opposition-controlled parliament and grappled with low approval ratings amid scandals involving himself and his wife. In his martial law announcement Tuesday night, Yoon called parliament a “den of criminals” bogging down state affairs and vowed to eliminate “shameless North Korea followers and anti-state forces.” The declaration of martial law was the first of its kind in more than 40 years in South Korea. The turmoil has paralyzed South Korean politics and sparked alarm among key diplomatic partners like the U.S. and Japan. “Yoon’s credibility overseas has been undermined by declaring martial law, so he won’t be able to exercise leadership in his foreign policies especially when his days are numbered,” said Kim, the Center for a New American Security analyst. “Its government bureaucracy will need to continue business as usual for existing alliance and foreign policy initiatives as best it can because there is a lot of important work to do globally.” Tuesday night saw special forces troops encircle the parliament building as army helicopters hovered overhead, but the military withdrew after the National Assembly unanimously voted to overturn the decree, forcing Yoon to lift martial law before daybreak Wednesday. Eighteen lawmakers from the ruling party voted to reject Yoon’s martial law decree along with opposition lawmakers. PPP later decided to oppose Yoon’s impeachment motion. Yoon’s speech fueled speculation that he and his party may push for a constitutional amendment to shorten his term, instead of accepting impeachment, as a way to ease public anger over the marital law and facilitate Yoon’s early exit from office. Lee told reporters that Yoon’s speech was “greatly disappointing” and that the only way forward is his immediate resignation or impeachment. His party called Yoon’s martial law “unconstitutional, illegal rebellion or coup.” Lawmakers on Saturday first voted on a bill appointing a special prosecutor to investigate stock price manipulation allegations surrounding Yoon’s wife. YOON ACCUSED OF ORDERING POLITICIANS’ ARRESTS On Friday, Han, the PPP chair who criticized Yoon’s martial law declaration, said he had received intelligence that, during the brief period of martial law, Yoon ordered the country’s defense counterintelligence commander to arrest unspecified key politicians based on accusations of “anti-state activities.” Hong Jang-won, first deputy director of South Korea’s spy agency, told lawmakers Friday that Yoon had ordered him to help the defense counterintelligence unit to detain key politicians, including the ruling party leader, the main opposition party leader and the speaker of the National Assembly. The Defense Ministry said Friday it suspended three military commanders, including the head of the defense counterintelligence unit, over their involvement in enforcing martial law. Vice Defense Minister Kim Seon Ho has told parliament that Defense Minister Kim Yong Hyun ordered the deployment of troops to the National Assembly. Opposition parties accused Kim of recommending to Yoon to enforce martial law. Kim Yong Hyun resigned as defense minister Thursday, and prosecutors imposed an overseas travel ban on him. We invite you to add your comments. We encourage a thoughtful exchange of ideas and information on this website. By joining the conversation, you are agreeing to our commenting policy and terms of use . More information is found on our FAQs . You can modify your screen name here . Comments are managed by our staff during regular business hours Monday through Friday as well as limited hours on Saturday and Sunday. Comments held for moderation outside of those hours may take longer to approve. Please sign into your Sun Journal account to participate in conversations below. If you do not have an account, you can register or subscribe . Questions? Please see our FAQs . Your commenting screen name has been updated. Send questions/comments to the editors. « Previous Next »None

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