REDWOOD CITY, Calif., Dec. 02, 2024 (GLOBE NEWSWIRE) -- Biomea Fusion, Inc. (Nasdaq: BMEA) (“Biomea” or the “Company”), a clinical stage biopharmaceutical company focused on the discovery and development of oral covalent small molecules to treat and improve the lives of patients with diabetes, obesity, and genetically defined cancers, today announced that on December 2, 2024, the compensation committee of Biomea’s board of directors granted one new employee non-qualified stock options to purchase an aggregate of 30,000 shares of the Company’s common stock. The shares underlying the employee’s stock options will vest 1/16 on a quarterly basis over four years, subject to the employee’s continued employment with the Company on such vesting dates. The above-described award was made under Biomea’s 2023 Inducement Equity Plan (the “Plan”). The above-described award was granted as an inducement material to the employee entering into employment with the Company in accordance with Nasdaq Listing Rule 5635(c)(4) and was granted pursuant to the terms of the Plan. The Plan was adopted by Biomea’s board of directors on November 17, 2023. About Biomea Fusion Biomea Fusion is a clinical-stage biopharmaceutical company focused on the discovery and development of oral covalent small molecules to improve the lives of patients with diabetes, obesity, and genetically defined cancers. A covalent small molecule is a synthetic compound that forms a permanent bond to its target protein and offers a number of potential advantages over conventional non-covalent drugs, including greater target selectivity, lower drug exposure, and the ability to drive a deeper, more durable response. We are utilizing our proprietary FUSIONTM System to discover, design and develop a pipeline of next-generation covalent-binding small-molecule medicines designed to maximize clinical benefit for patients. We aim to have an outsized impact on the treatment of disease for the patients we serve. We aim to cure. Visit us at biomeafusion.com and follow us on LinkedIn , X and Facebook . Contact: Investor & Media Relations Ramses Erdtmann re@biomeafusion.com
The would-be assassin of former President Ronald Reagan has a new business venture, he announced Monday. John Hinckley Jr., who shot and wounded Reagan in 1981 and was acquitted by reason of insanity, had spent decades in a Washington mental health hospital after the assassination attempt. Since being freed from court oversight in 2022, Hinckley has spent recent years posting videos of his music and promoting live shows. And on Monday, Hinckley announced he would be opening up a music store. “I’ll be opening a music store in Williamsburg, Va. The address is 455 Merrimack Trail. Grand opening is in a week or two!” he wrote on social media platform X. I’ll be opening a music store in Williamsburg, Va. The address is 455 Merrimack Trail. Grand opening is in a week or two! Hinckley has also promoted his live music shows on X, but has noted that some venues have cancelled on him in the past. He also posts his music to his YouTube channel. After the 2024 election, Hinckley told his followers to stop with the “negative” comments. “A lot of the comments on my Twitter/X feed have been alarming, so I have to keep reminding people that I am a changed person from the way I was in 1981,” he wrote in a blog post. “My songs are about peace and love and overcoming hard times. A lot of people have told me that listening to my songs helps them get through their day. I strive for positive vibes, not the negativity you see everywhere today,” he added. Hinckley told The New York Times in a July interview that he uses music to “redeem” himself. “People have different definitions of redemption,” Hinckley told The New York Times. “My definition of redemption is to make amends for all the negativity that I created in 1981. I’m trying to redeem myself through positive music, through a thing that people really like — as opposed to the things they really hated about me, in 1981.” He also said in the interview that while he enjoys living in Williamsburg, Va. because people do not bother him, he has thought about living in more music-centered cities like Nashville, Los Angeles or New York. “I’m basically a struggling musician,” he told the Times. “I’ve had a lot of people say to me, ‘John, you’re like so many other struggling musicians.’ And it’s true. I am.” Hinckley did not provide any other details about his music store on social media on Monday. Stories by Lauren Sforza Who would Trump FBI nominee Kash Patel target? He compiled a lengthy list Trump supporters called out for hypocrisy after Biden pardon ‘Utter bull---t’: Biden allies, Trump rip move to pardon Hunter Biden Our journalism needs your support. Please subscribe today to NJ.com .
As a participant in multiple affiliate marketing programs, Localish will earn a commission for certain purchases. See full disclaimer below* Whether you're looking to upgrade your next movie night setup or hoping to game with higher-quality graphics, Cyber Monday is a great time to get the best TVs for a lower price. We rounded up some of the biggest sales going on right now to help you save on your next TV purchase. Best Cyber Monday TV deals for 2024 This TV is a great option for your living room, bedroom or office. Measuring 32 inches, it's decently sized, yet still easy to fit on a table or TV stand. It's also an Amazon Fire TV, so you'll have access to a wide variety of channels and apps. Currently, you can get it for under $100 at 46% off. This TV has been rated five stars over 30,000 times on Amazon, and it's currently on sale for 27% off. It's compatible with both Alexa and Google Assistant and since it's a Roku TV, you'll have access to tons of channels and apps. You can get this great Fire TV for 38% off. It's compatible with 4K Ultra HD, Dolby Digital Plus and Alexa Voice. Amazon is also offering six months free of an MGM+ subscription with the purchase of this TV. This 4K Ultra HD TV is an Amazon bestseller and is currently on sale for 37% off. Enjoy high-quality resolution and a large screen size. This TV also comes with Alexa voice, so you can easily speak commands into the remote. This 85-inch TV is perfect for larger rooms and offers 4K resolution and accurate color representation thanks to Samsung's PurColor technology. Shop it now below $1,000. If you're looking for a larger TV, this Toshiba 75-inch is a great deal. It boasts 4K resolution and both Dolby Vision HDR and Dolby Atmos. Save $200 on this TV for Cyber Monday. Enjoy cinematic 4K TV quality with this 75-inch Amazon Fire TV, which comes with Dolby Vision and Alexa voice control. If you're looking for a large family room TV, this deal is a steal. Get this 100-inch Hisense TV for over $1,000 off right now. Both the QLED display technology and advanced full array local dimming bring you a high-quality viewing experience. Plus, this TV is also compatible with Alexa and Google Assistant. More TV deals below: Amazon 50-inch Fire TV for under $300. SAMSUNG 55-inch Class DU6900 Crystal UHD 4K Smart TV for under $300. LG 43-inch Class 4K UHD 2160P webOS Smart TV for just $350. *By clicking on the featured links, visitors will leave Localish.com and be directed to third-party e-commerce sites that operate under different terms and privacy policies. Although we are sharing our personal opinions of these products with you, Localish is not endorsing these products. It has not performed product safety testing on any of these products, did not manufacture them, and is not selling, or distributing them and is not making any representations about the safety or caliber of these products. Prices and availability are subject to change from the date of publication.Donald Trump is returning to the world stage. So is his trolling
The Arizona Cardinals are 6-6 through 12 games, which makes them an average football team. That's much better than the previous two years, which both ended with just four wins. But after two straight frustrating losses, it's not providing much consolation for a franchise that feels as though it should be much better. The latest setback came on Sunday, when the Minnesota Vikings rallied to beat the Cardinals 23-22 . Arizona never trailed until Sam Darnold threw a 5-yard touchdown pass with 1:18 remaining that proved to be the winning score. It was a mistake-filled performance for the Cardinals, who racked up 10 penalties for 96 yards. That's a big reason they had to settle for five field goals and scored just one touchdown. The Cardinals were leading 19-16 in the fourth quarter and had first-and-goal at the Vikings 5, but Tip Reiman was called for a false start and then quarterback Kyler Murray was called for intentional grounding . The Cardinals kicked a field goal for a 22-16 lead, giving the Vikings the chance they needed to drive for the winning score. Murray threw two interceptions in the fourth quarter. “I thought we moved the ball well,” Murray said. “Again, it just comes down to not scoring touchdowns. Get down there and kick field goals and penalties bite us. It’s bad — it’s bad football.” The loss knocked the Cardinals out of first place in the NFC West, though they're still in decent playoff position. A pivotal game against the division-rival Seahawks looms on Sunday. Second-year coach Jonathan Gannon acknowledged the frustration of Sunday's loss, but said they've got to rebound quickly. “They’re disappointed and down, but it’s the NFL,” Gannon said. “They’ve got to put all their energy and focus into tomorrow.” What’s working Arizona's defense blamed itself for not coming up with a stop on the Vikings' winning drive, but the unit played exceptionally well for most of the afternoon. Mack Wilson and L.J. Collier both had two sacks and the Cardinals held Minnesota to just 273 total yards. For a group that looked as if it might be the team's weakness this season, it was another rock solid performance. What needs help The Cardinals aren't a good enough football team to overcome 10 penalties and get a win — particularly on the road. Reiman had a rough day, getting called for three false starts. His false start on the next-to-last offensive drive — coupled with Murray's intentional grounding penalty — proved to be extremely costly. “That was brutal,” Gannon said. “Just got to figure out ways to punch the ball in for touchdowns there, not field goals.” Stock up Rookie Marvin Harrison Jr. had five catches for 60 yards, including an impressive touchdown catch that put the Cardinals up 19-6. It was Harrison's seventh TD reception of the season. The No. 4 overall pick has been a little inconsistent in his first year, but there's little doubt he's a difference-maker for the offense. He's still got a chance to reach 1,000 yards receiving this season if he averages about 80 yards receiving over the final five games. Considering his talent, that's certainly possible. Stock down Gannon was second-guessed for his decision to kick a field goal late in the fourth quarter instead of trying for a touchdown at the Vikings 4 with 3:29 left. Chad Ryland made the 23-yard chip shot for a 22-16 lead, but the Vikings drove the field on the ensuing possession for the winning score. “I trust JG,” Murray said. “I see both sides. Go up six and make them score; trust the defense to go get a stop. Go for it, you don’t get it, they’ve still got to go down and score. If you do get it, you probably put the game away.” Said Gannon: "Yeah, I mean there’s thought about it. Just wanted to go up more than a field goal there. Definitely a decision point that we talked about. So be it.” Injuries The Cardinals came out of the game fairly healthy. Rookie DL Darius Robinson — the No. 27 overall pick — made his NFL debut against the Vikings after missing the first 11 games due to a calf injury. Key number 1,074 — Running back James Conner's total yards from the line of scrimmage this season, including 773 on the ground and 301 in the passing game. Next steps The Cardinals return home for a game against the Seahawks on Sunday. ___ AP NFL: https://apnews.com/hub/nfl David Brandt, The Associated PressMiners down Mount CarmelRuud van Nistelrooy 'hurt' and lifts lid on 'man-to-man' chat with Man Utd boss Amorim
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