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Downstream Processing Market Witnesses Rapid Growth Fueled by Biopharmaceutical Demand and Technological Advancements | Report by S&S InsiderClearwater Paper Co. (NYSE:CLW) Shares Sold by Public Sector Pension Investment Board
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Austin, Dec. 08, 2024 (GLOBE NEWSWIRE) -- The S&S Insider report indicates that, “ The Downstream Processing Market was valued at USD 29.35 Billion in 2023 and is projected to reach USD 99.64 Billion by 2032, growing at a compound annual growth rate (CAGR) of 14.60% from 2024 to 2032. ” Accelerating Growth of the Downstream Processing Market The downstream processing market is experiencing rapid expansion, fueled by the surging demand for biopharmaceuticals such as vaccines, monoclonal antibodies, and enzymes. This growth is driven by the rising prevalence of chronic diseases and advancements in biotechnology, which have spurred the development of biologics. With global pharmaceutical industry revenues reaching approximately USD 1.6 trillion in 2023, biopharmaceuticals have emerged as a significant and fast-growing segment. Downstream processing is pivotal in ensuring the efficient purification and recovery of these complex products, promoting further innovation in the field. This innovation is reflected in the adoption of advanced technologies like single-use systems, membrane chromatography, and continuous processing. By Q1 2023, over 100 approved gene, cell, and RNA therapies, alongside 3,700 therapies in development, underscored the rising need for scalable solutions. These advancements enhance operational efficiency, reduce costs, and support the increasing global demand for biologics. Download PDF Sample of Downstream Processing Market @ https://www.snsinsider.com/sample-request/2618 Key Players: Merck KGaA (MilliporeSigma) (Viresolve Barrier Filters, ProSep Ultra Plus Protein A Resin) Sartorius Stedim Biotech S.A (Sartobind Membrane Adsorbers, Sartoflow Advanced Systems) Thermo Fisher Scientific Inc. (POROS Chromatography Resins, CaptureSelect Affinity Ligands) Danaher Corporation (Pall Allegro MVP Single-Use System, Cytiva ReadyToProcess Columns) Repligen (OPUS Pre-packed Columns, XCell ATF Systems) 3M Company (Zeta Plus Depth Filters, Emphaze AEX Hybrid Purifiers) Boehringer Ingelheim International GmbH (BIHEX Process Solutions, Biopharmaceutical Contract Services) Corning Corporation (Corning CellCube Systems, X-Series Hollow Fiber Filters) Lonza Group Ltd (Centrifuge Systems, Viral Clearance Services) Dover Corporation (Quattroflow Diaphragm Pumps, Maag Industrial Filtration Solutions) Asahi Kasei (Planova Virus Filters, Microza UF Membranes) Eppendorf AG (Centrifuge 5910 R, BioFlo Bioprocess Controllers) Finesse Solutions Inc. (Thermo Fisher Subsidiary) (SmartVessel Bioreactor, G3Lab Universal Controllers) Purolite Life Sciences (Praesto Protein A Resins, Chromalite Ion Exchange Resins) Tosoh Bioscience (TOYOPEARL Protein A Resins, TSKgel Chromatography Columns) Novasep (BioSC Chromatography Systems, Prochrom Bio Columns) MilliporeSigma (a subsidiary of Merck KGaA) (Durapore Filters, Chromabolt Pre-packed Columns) Waters Corporation (PATROL UPLC Process Analyzer, AutoPurification Systems) PerkinElmer Inc. (LabChip GXII Microfluidics System, QSight 420 Mass Spectrometer) Bio-Rad Laboratories, Inc. (UNOsphere Chromatography Resins, NGC Chromatography Systems) Avantor (VWR) (J.T.Baker High Purity Solvents, Arium Sterile Filtration Units) Spectrum Labs (Repligen subsidiary) (KrosFlo TFF Systems, Hollow Fiber TFF Modules) Meissner Filtration Products (UltraCap Depth Filters, FlexGro Single-Use Assemblies) Downstream Processing Market Report Scope: If You Need Any Customization on Downstream Processing Market Report, I nquire Now @ https://www.snsinsider.com/enquiry/2618 By Application , Antibiotics Dominate While Antibodies Drive Rapid Growth in Downstream Processing Market In 2023, the Antibiotic Production segment captured 34% of the downstream processing market revenue, driven by global demand to combat bacterial infections. Their widespread application in healthcare and agriculture, coupled with mature manufacturing practices, ensures large-scale production and steady revenues. Cost-effective purification methods and antibiotics' essential role in public health further solidify this segment's dominance. The Antibodies Production segment is expected to grow at a CAGR of 16.51% from 2024 to 2032, fueled by rising demand for monoclonal antibodies and biosimilars to treat cancer and autoimmune diseases. Innovations in scalable downstream technologies, such as chromatography and single-use systems, and a robust pipeline of therapies are accelerating growth, highlighting the segment’s expanding prominence in biopharma. By Technique , Chromatography Leads While Solid-Liquid Separation Drives Future Growth In 2023, the Purification By Chromatography segment accounted for 42% of the downstream processing market revenue, owing to its unmatched ability to deliver high-purity biomolecules. Its adaptability for diverse biopharmaceuticals, including monoclonal antibodies and vaccines, has positioned it as a vital industry tool. Ongoing technological advancements have further solidified its role as the most reliable purification method. The Solid-Liquid Separation segment is poised to grow at the fastest CAGR of 16.99% from 2024 to 2032, driven by rising demand for efficient filtration and centrifugation solutions. Its critical role in biologics and cell therapy production, coupled with a shift toward sustainable and cost-effective manufacturing, drives innovation. These factors underline its importance in meeting the evolving needs of the biopharma sector. North America Dominates, Asia Pacific Drives Rapid Growth In 2023, North America accounted for 36% of the downstream processing market revenue, led by its strong biopharmaceutical industry and advanced R&D infrastructure. Substantial investments in manufacturing technologies and the presence of major market players have reinforced its dominance. High demand for biologics and favorable regulatory support further cement its leadership. The Asia Pacific region is set to grow at the fastest CAGR of 16.68% from 2024 to 2032, driven by increasing biopharma investments and expanding healthcare infrastructure. Government initiatives promoting local biomanufacturing and cost-efficient production capabilities are key growth drivers. The region's rising demand for biologics and biosimilars underscores its growing role in the global market. Buy Full Research Report on Downstream Processing Market 2024-2032 @ https://www.snsinsider.com/checkout/2618 Key Developments in the Downstream Processing Market On November 21, 2024, Sartorius Stedim Biotech inaugurated its Center for Bioprocess Innovation in Marlborough, USA, focusing on cell and gene therapy manufacturing with GMP suites set to open in 2025. On November 7, 2024, Thermo Fisher Scientific announced the construction of a 10,000-square-foot Bioprocess Design Center in Hyderabad, India, to advance biotherapeutics manufacturing, opening in early 2025. Table of Contents – Major Key Points 1. Introduction Market Definition Scope (Inclusion and Exclusions) Research Assumptions 2. Executive Summary Market Overview Regional Synopsis Competitive Summary 3. Research Methodology Top-Down Approach Bottom-up Approach Data Validation Primary Interviews 4. Market Dynamics Impact Analysis Market Driving Factors Analysis PESTLE Analysis Porter’s Five Forces Model 5. Statistical Insights and Trends Reporting Regulatory Approvals Technological Adoption Rates Cost Contributions Regulatory Approvals 6. Competitive Landscape List of Major Companies, By Region Market Share Analysis, By Region Product Benchmarking Strategic Initiatives Technological Advancements Market Positioning and Branding 7. Downstream Processing Market Segmentation, by Application 8. Downstream Processing Market Segmentation, by Product 9. Downstream Processing Market Segmentation, by Technique 10. Regional Analysis 11. Company Profiles 12. Use Cases and Best Practices 13. Conclusion Speak with O ur E xpert A nalyst T oday to G ain D eeper I nsights @ https://www.snsinsider.com/request-analyst/2618 [For more information or need any customization research mail us at info@snsinsider.com ] About Us: S&S Insider is one of the leading market research and consulting agencies that dominates the market research industry globally. Our company's aim is to give clients the knowledge they require in order to function in changing circumstances. In order to give you current, accurate market data, consumer insights, and opinions so that you can make decisions with confidence, we employ a variety of techniques, including surveys, video talks, and focus groups around the world.Argil Raises $5.2 Million for AI-Powered Video-Generation ToolBrits urged to check their change for rare Christmas 50p coin worth £300
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The Houston Texans lost their Week 12 matchup 32-27 to the Tennessee Titans. It was a surprising loss, considering Houston is viewed as a legitimate playoff contender, while Tennessee managed to earn its third win on the season on Sunday. It was a back-and-forth game throughout, with CJ Stroud playing well for the most part. However, the Titans' defense did manage to force him to throw two interceptions on the day. The 23-year-old quarterback finished the day with 247 passing yards, two touchdowns, and two interceptions while throwing a 60.6% completion percentage. Houston falls to a 7-5 record on the season and still holds a two-game lead over the second-placed Indianapolis Colts in the AFC South. Despite that, all of the attention is on Stroud after the second-year quarterback made a total blunder of a play to lose the game. Backed in his own end zone, Stroud dropped back to pass with just over a minute left to play. However, the Titans' pass rush got in the backfield and forced Stroud to scramble. While scrambling, the Texans' quarterback stepped out of the back of the end zone, resulting in a safety . Tennessee scored two points and got the ball back before kneeling out the clock. Did CJ Stroud run out the back of the end zone, or get sacked out the back or the end zone? 😳😳😳 @danorlovsky7 , obviously you are the ultimate arbitrator. pic.twitter.com/f7voVjXbiB The play is reminiscent of a safety former NFL quarterback Dan Orlovsky made during his playing days in the league. During a 2008 game between the Detroit Lions and Minnesota Vikings, Orlovsky notoriously ran out of bounds in his own end zone as the quarterback for the Lions. However, Orlovsky's mishap was noticeably worse . For Stroud, at least, it's arguable a Titans defender tackled him out of bounds. SAI Flashback: October 12, 2008 Dan Orlovsky ran out of the back of his own end zone and didn’t even realize it at first pic.twitter.com/1AWXkNmn0s Regardless, sports fans hopped on social media to point out Stroud's mistake. Many of them compared the Texans quarterback to Orlovsky's blunder from 2008. Meanwhile, others criticize Stroud for taking a step back in production during his second year in the NFL. © Troy Taormina-Imagn Images "CJ Stroud, the back of the end zone is bad!" Stated Big Cat from Barstool Sports . One fan claimed , "Dan Orlovsky will tell ya it’s not good!" "What in the world has happened to CJ Stroud....? Legit looks like an average QB at best week in and week out," claimed another fan . NFL Hall of Famer Shannon Sharpe asked , "What's happened [to] CJ Stroud? He looks and plays like a totally different player. Is it me or is he different?" "CJ Stroud turned into Dan Orlovsky before he made a second year leap," said one individual . The Texans have five games remaining on the schedule before the regular season ends. They'll be taking on the Jacksonville Jaguars in Week 13 to try and get back in the win column. Related: C.J. Stroud is grateful to have Nico Collins back from injured reserve
Bill Belichick: The greatest football coach of all time, who accounts for eight Super Bowl rings and is a sure-fire, first-ballot Hall of Famer. That is, until he hangs up the whistle, which might not be just yet. His last season in New England wasn’t a great one, with the Patriots winning just four games and picking third in the 2024 NFL Draft. After a year of being unemployed, I thought Belichick would use this time to lay low and enjoy a break from football. Boy, was I wrong. From appearing on nearly every Monday Night Football game to join “ManningCast,” to being a weekly contributor on “The Pat McAfee Show,” and even showing up to “The Roast of Tom Brady,” Belichick has done everything but take a break, it seems. Now, we’re at the point of the NFL season when rumors are starting to swirl about future landing spots for coaches. There are many prominent names that will be available beyond Belichick, like Detroit Lions offensive coordinator Ben Johnson, and former Titans head coach Mike Vrabel, among others. And this past week or so, rumors came to light that Belichick has been in contact with the University of North Carolina at Chapel Hill to become its next football coach. My immediate reaction: UNC?! I’ll state my bias now: I like Duke (because of Coach K), so I automatically hate UNC. Funny how that works... My second thought was, man, NFL teams just don’t think Belichick is worth the risk. Listen, he’s the greatest coach ever. There’s no denying that, says a 20-something year old living in New England. However, he’s 72 years old and after Tom Brady left for Tampa Bay, it’s not like Belichick left the Patriots in the best of conditions. He’s going to want full control and most programs don’t want to give coaches that. Ugh, Bill wearing light blue, as opposed to New England navy. I’m still shocked. I never thought he’d go the college route, unless he was a general manager or something. But love him or hate him, Belichick in the world of college football would be some spectacle. Reports suggest that Belichick would want to turn North Carolina into an NFL pathway, where players who choose to go there will be coached like NFL players, train like professionals, and live a day-to-day life, balancing school and their “profession.” Now, the question is, would it work? I’m hesitant to believe it would. I’m sure UNC will get a lot of high-end recruits who want to learn from Belichick, but if Nick Saban got tired of coaching because of NIL, I can’t see how Belichick would like it either. Like a talented director dealing with Hollywood producers, If UNC gives Belichick complete control of his project, then maybe – just maybe – it could work. After all, I guess we shouldn’t be too surprised that Belichick has an interest in UNC. His favorite defensive player of all time, Lawrence Taylor, went there. Personally, I want to see Belichick break the NFL wins record, but if teams don’t want to hire him, then I guess I can secretly root for UNC football to do well.For a man who plays as hard as he does, Pieter-Steph du Toit’s second World Player of the Year award, following his 2019 gong, is a testament to his fitness and mentality. Du Toit was honoured with the award in Monaco on Sunday, beating out fellow Springboks Eben Etzebeth and Cheslin Kolbe, and Ireland No 8 Caelan Doris. Such was the quality of the quartet, and particularly the Bok trio on the nominations list, that anyone of them could have won and it wouldn’t have felt like an injustice. Du Toit produced another colossal body of work in 2024, playing just about every minute of every match in which he represented the Boks this year. This award was deserved and also a nod to his remarkable consistency, playing in one of the most demanding positions in all of sport. And he has been doing it for 12 years, with almost three years lost to various injuries. He’s won the SA Player of the Year award three times as well, but the 2024 World Rugby accolade might be his greatest yet for the ultimate team man. Read more: Pieter-Steph du Toit makes rugby comeback 398 days later He won it in a year where so many great players operated at a stratospheric level. Etzebeth must surely be wondering if he can play any better, while contributing to perhaps the greatest Bok team of all time. He was sensational in 2024, picking up from the form he displayed in 2023 where he was unlucky to lose out to Ardie Savea for the award. Kolbe too, continues to defy age and workload and Doris was superb all season, capping a fine year with a world-class display as he led Ireland to victory over the Boks in Durban. Eben Etzebeth (second from left) was nominated for the World Rugby Player of the Year award, along with Pieter-Steph du Toit (far right) and Cheslin Kolbe (not pictured). (Photo: Juan Jose Gasparini / Gallo Images) Du Toit cemented his place in history by becoming the first South African to be named the World Men’s 15s Player of the Year for a second time. All Black greats Dan Carter and Richie McCaw won it three times and, until Du Toit, Beauden Barrett was the only other player to win it more than once since the award’s inception in 2001. Read more: Pieter-Steph du Toit narrowly escapes leg amputation The 32-year-old Du Toit was one of seven Springbok Rugby World Cup winners named in the 2024 Dream Team. The trio of Du Toit, Etzebeth and Kolbe were joined in the side by Ox Nche (prop), Malcolm Marx (hooker), and the centre pairing of Damian de Allende and Jesse Kriel – which capped off a rewarding evening for the top ranked side in the world. New Zealand’s Wallace Sititi pipped talented young Springbok flyhalf Sacha Feinberg-Mngomezulu for the Men’s 15s Breakthrough Player of the Year award, while Jérôme Daret, who led the French men’s sevens team to the Olympic gold medal in Paris, was named Coach of the Year. Pieter-Steph du Toit of South Africa during the Autumn Nations Series 2024 match against England at Allianz Stadium (Twickenham). (Photo: Visionhaus / Getty Images) The glittering event also highlighted other South African contributions to global rugby. Selvyn Davids, captain of the Blitzboks, earned a spot in the Men’s Sevens Dream Team, while SA Rugby won the Rugby for All Award, which celebrates impactful initiatives that uphold rugby’s core values. SA Rugby’s “The Bag That Builds” project was particularly commended for promoting sustainability by repurposing tournament waste into building materials for community housing projects. SA Rugby President Mr Mark Alexander lauded all the players for being honoured in such a remarkable year for the Boks, in which they registered an 85% win record after claiming the Rugby Championship title as well as the Nelson Mandela Challenge Plate, Freedom Cup and Prince William Cup (against Wales), and said this was a just reward for their fine efforts on the field this season. “On behalf of SA Rugby, I’d like to extend our since congratulations to Pieter-Steph and all the players named in the Dream Team for receiving this recognition for all the hard work they’ve been putting in on and off the field this year, as well as Selvyn for his consistently great performances during a challenging season for the Blitzboks,” said Alexander. “For Pieter-Steph to become the first South African to win the World Rugby Player of the Year award twice is a notable achievement, and to have seven Boks in total feature in the Dream Team is simply remarkable. “Springbok coach Rassie Erasmus has built something special with the Bok team, and the way the players give their all week in and week out is an inspiration to us all and shows that hard pays off. “We are very proud of them and the entire Springbok coaching and management team for their tireless efforts to ensure that our players continue to shine on the international stage.” The recognition for their colossal performances in the green and gold this season, which contributed immensely to the team’s 11 victories in 13 matches, followed on nominations for Etzebeth in 2013 and last year, and Kolbe and Du Toit in 2019, respectively. Other South Africans who received nominations for the Men’s 15s Player of the Year Award in the last decade are Willie le Roux and Duane Vermeulen (both in 2014), Faf de Klerk and Malcolm Marx (both in 2018), and Lukhanyo Am (2022). Apart from Du Toit, only two other South Africans have walked away with top honours – Schalk Burger in 2004 and Bryan Habana in 2007. Erasmus was also full of praise for the players and entire Springbok team and said: “To have so many of our players feature in the awards is a testament to their hard work, and dedication to the team and the Springbok brand, and that’s what makes this such a special group. “What makes this achievement even significant is that we used 50 players in total this season and rotated our squad regularly, which shows the calibre of players they are. But rugby is a team sport, and it takes each one of the squad members to do their bit to place one another in positions to shine. “With the vast player depth in our squad, I’m sure a few more players were close to being nominated, but each one of these players certainly deserves this recognition and we are very proud of them.” Erasmus also thanked the entire Bok squad for their efforts this season: “It takes each person in a squad to perform their role proficiently to ensure that the players can deliver on the field, so thank you to the winners and Dream team players, as well as every other player who has been part of the squad this year.” DM
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