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Sask. NDP 'blocked' from tabling emergency motion to suspend gas taxThe China Fund, Inc. Announces Date of Annual Meeting of Stockholders
NEW YORK — The last of the crystal triangles that make up this year's Times Square New Year's Eve ball were installed Friday morning. It's the first time in 10 years that all 2,688 were replaced at once. Singer Pitbull attends the Times Square New Year's Eve Ball Crystal Installation on Friday at One Times Square in New York. Rapper Pitbull and inventor Joy Mangano were among those on hand to help the organizers of the celebration put the final pieces in place atop One Times Square, the skyscraper from which the 11,875-pound geodesic sphere drops to mark the new year. Singer Pitbull, left, and Joy Mangano, right, founder of CleanBoss, install a crystal Friday during the Times Square New Year's Eve Ball Crystal Installation at One Times Square in New York. A New Year's Eve ball was first dropped in Times Square in 1907. Built by a young immigrant metalworker named Jacob Starr, the 700-pound, 5-foot diameter ball was made of iron and wood and featured 100 25-watt lightbulbs. Six newer versions of the ball were featured in the century-plus since that first celebration. Times Square New Year's Eve Ball is displayed Friday at One Times Square in New York. The only years no ball drop occurred were 1942 and 1943, when the city instituted a nightly "dimout" during World War II to protect itself from attacks. Crowds instead celebrated the new year with a moment of silence followed by chimes rung from the base of One Times Square. As the new year approaches, many people begin thinking about their resolutions—typically focusing on physical health, saving money, or spending more time with family. One area that often gets overlooked is mental health. The pressure to "get fit" or "eat better" is well-known, but taking care of mental well-being is just as important as improving physical health, especially since mental health impacts every aspect of life. At first glance, mental health goals can seem intangible and subjective, but there are scientifically-proven ways to set achievable, measurable, and personalized mental wellness goals that will help anyone thrive in 2025. Vivian Chung Easton, a mental health therapist at Blueprint , a company focused on building AI-powered tools to help therapists, shares recommendations for setting mental health resolutions. One of the most important mental wellness goals for 2025 is to prioritize self-compassion and resilience. In a culture that often celebrates hustle and perfection, it's easy to push yourself too hard, setting unrealistic expectations that only add to stress and anxiety. But research shows that self-compassion and resilience are critical factors in coping with stress and maintaining long-term mental well-being. A 2021 study by Kristin Neff and Christopher Germer highlights that self-compassion—treating yourself with kindness when things don't go as planned—can reduce emotional distress and improve resilience. Instead of criticism for not meeting a goal or making a mistake, practice affirmations or positive self-talk. A simple goal, like being kinder to yourself during setbacks, can help reduce stress and boost mental wellness. A goal can look something like this: Making room for self-compassion this year can be a transformative step toward building resilience and enhancing overall mental health. Social connection is one of the most important factors in mental wellness, yet it's often overlooked in favor of individual self-improvement goals. Physical isolation can lead to loneliness, but social isolation is also strongly linked to mental health challenges like depression and anxiety, according to a study by Juliannee Holt-Lundstad. Meaningful relationships and community support can improve how satisfied you feel in your life on a day-to-day basis. This year, make it a goal to strengthen and nurture social connections, whether that means reconnecting with old friends, regularly scheduling family time, or joining social groups and clubs—like a book club, gym, or church group. For example, a social wellness goal can look like: Building mental wellness isn't just about managing thoughts and feelings; it's also about fostering a strong support network. Social connections are integral to building emotional resilience. Just as physical fitness is associated with physical health, mindfulness is often associated with mental fitness. However, practicing mindfulness is just as important as going for a run or lifting weights when it comes to mental wellness. Mindfulness-based practices—such as meditation, yoga, or breathing exercises—have been shown to reduce symptoms of anxiety and depression, improve focus, and boost emotional well-being according to research by Stefan Hofman in the Journal of Consulting and Clinical Psychology. Incorporating mindfulness into a routine doesn't have to be time-consuming or difficult. Start small by committing to 5–10 minutes of mindfulness practice a few times a week . Focus on breath, practice guided meditation, or even engage in mindful walking or eating. A simple goal might be: These exercises are called a practice for a reason: doing them consistently and often can strengthen your ability over time. These practices not only reduce stress in the moment but also help to build resilience over time, making it easier to handle future challenges. Whatever New Year's resolution you might have, a large obstacle is setting goals that are too ambitious or unrealistic. Whether it's aiming to exercise every day or cutting out all sugar, overambitious goals can lead to burnout and disappointment when progress isn't immediate. This is especially true for mental health goals, which often require patience and consistency. Using these suggestions for mental health goals, focus on how to personalize them to make them realistic and achievable for your life. Research from the American Psychological Association shows that people are more likely to succeed in their resolutions when they set realistic and incremental goals. Instead of vague, broad goals like "be happier" or "stress less," focus on small, concrete actions that can lead to big changes over time. One effective approach is to use SMART goals—goals that are Specific, Measurable, Achievable, Relevant, and Time-bound. For example: These specific, measurable actions make it easier to track progress and feel a sense of accomplishment along the way. Plus, they're more realistic and achievable, which increases your chances of success. It happens every year—gyms always seem to empty out before spring starts. One of the challenges of New Year's resolutions is that many people abandon their goals as early as January. However, mental health goals require ongoing attention and flexibility. Unlike weight loss or fitness goals, mental wellness is a journey, not an endpoint. Regularly tracking progress is essential. By setting aside time to evaluate personal progress, it's easier to adjust your goals and make necessary changes to keep things on track. Research shows that regular goal check-ins increase the likelihood of long-term success. Consider setting quarterly check-ins with yourself to assess your mental health goals: If you're not meeting your targets, adjust them to make them more realistic. Mental health progress doesn't always follow a straight line, so it's important to be flexible and forgiving with yourself. The new year is inherently a time of change, and that can be a helpful mindset in seeing new potential for growth and taking action. As you set your resolutions for 2025, don't forget to prioritize mental wellness. By focusing on achievable, realistic goals—you're setting yourself up for a healthier, more fulfilling year. Mental health is just as important as physical health, and nurturing it can help to reach other goals more effectively. Even if, in a month or two, you feel like you're falling behind—mental health goals can and should be flexible and adaptable. You can always adjust your approach if things aren't serving you, and check in with yourself regularly to stay on track. Goals are personal, and you're always in control. Here's to a year of growth, balance, and emotional well-being in 2025. This stor y was produced by Blueprint and reviewed and distributed by Stacker. Photo Credit: Alberto Menendez Cervero / Shutterstock As anyone who’s ever started a business knows, getting one off the ground is not for the faint of heart. Entrepreneurs face numerous challenges in the early years, from solidifying business plans to navigating the complexities of hiring employees and acquiring licenses and insurance. These hurdles often determine the fate of a startup, making the journey from an idea to a successful enterprise both difficult and uncertain. Each year, millions of Americans file new business applications , but only a fraction of these ventures transition to hiring employees. Among those that do, surviving the critical first few years can still be an uphill battle. However, survival rates differ significantly by location, influenced by a variety of factors such as economic conditions, state policies, and industry-specific demand. The good news is that businesses that weather the initial hurdles see a much greater likelihood of long-term success. This analysis explores the states where new businesses are most likely to survive their earliest years based on the latest data from the U.S. Bureau of Labor Statistics (BLS). The findings reveal important insights into how location and time impact the chances of business success. The chances of staying in business increase dramatically after the first few years Source: Simply Business analysis of U.S. Bureau of Labor Statistics data | Image Credit: Simply Business One of the most significant challenges for new business owners is simply staying in operation. The risk of failure is highest during the first year, but it diminishes considerably over time. For those businesses that survive the initial hurdles, the likelihood of long-term success grows each year. According to recent BLS data, only about 79% of businesses survive their first year, making it the most difficult period for startups. However, for businesses that survive their first year, roughly 85% make it to the next. By the fifth year, 91% of businesses manage to continue operations, and for those that reach the 10-year mark, an impressive 93% make it through to another year. These figures underscore the importance of persistence and adaptability, especially during the critical early years when the risk of failure is highest. They also highlight that while starting a business is undeniably challenging, those who endure the startup years enjoy far better odds moving forward. Washington & California lead the country in new business survival rates Source: Simply Business analysis of U.S. Bureau of Labor Statistics data | Image Credit: Simply Business New business success varies widely across the United States, with some states providing a more favorable environment for startups to thrive. Based on survival rates for the first three years of operation, Washington and California stand out as the nation’s leading states. Washington claims the top spot, with businesses in the state enjoying an 86.4% chance of surviving their first year, 89.3% in their second year, and an impressive 91.8% in their third year. These figures highlight Washington's robust support for young businesses, likely fueled by its thriving tech ecosystem and a generally favorable economic climate. California ranks second, with survival rates of 86.0% in the first year, 89.8% in the second, and 91.4% in the third. Despite challenges such as high costs of living and regulatory complexities, California’s strong economy, innovation hubs, and access to venture capital contribute to its high ranking. Outside of the West Coast, West Virginia —whose economy is deeply rooted in energy production, natural resources, and manufacturing—ranks third, boasting the highest third-year survival rates at 91.9%. North Carolina —a major banking center and home of the Research Triangle—follows closely with similar numbers. At the opposite end of the spectrum, Minnesota businesses face the toughest challenges in their early years, with only 72.3% surviving their first year and 80.2% their second. These regional differences highlight the importance of local economic conditions in shaping a startup's odds of success. For entrepreneurs planning their next move, this analysis offers insight into where businesses are thriving and where challenges are more pronounced. Factors like industry presence, regulatory environments, and access to resources can create opportunities—or hurdles—that significantly affect survival rates in the critical early years. Choosing the right location isn’t just about personal preference; it can mean the difference between failure and success. This analysis was conducted by Simply Business —an online insurance marketplace for small businesses—using 2024 data from the U.S. Bureau of Labor Statistics. For complete results, see the original post: States Where New Businesses Are Most Likely to Succeed . Photo Credit: Alberto Menendez Cervero / Shutterstock The data in this report comes from the U.S. Bureau of Labor Statistics’ Business Employment Dynamics . To determine the states where new businesses are most likely to succeed, researchers at Simply Business developed a business survival index. This index is based on a weighted average of the most recent survival rates for private-sector establishments during their first, second, and third years of operation, as of March 2024. The survival rates were calculated using sequential benchmarks. The first-year survival rate is the percentage of businesses still active one year after opening. The second-year rate is the percentage of those first-year survivors that remained operational for another year. Similarly, the third-year rate is the percentage of second-year survivors that continued into the following year. The data focuses exclusively on private-sector businesses with at least one employee. For complete results, see States Where New Businesses Are Most Likely to Succeed on Simply Business. Receive the latest in local entertainment news in your inbox weekly!The China Fund, Inc. Declares DistributionsNEW YORK, Nov. 26, 2024 (GLOBE NEWSWIRE) -- The Gross Law Firm issues the following notice to shareholders of Edwards Lifesciences Corporation (NYSE: EW). Shareholders who purchased shares of EW during the class period listed are encouraged to contact the firm regarding possible lead plaintiff appointment. Appointment as lead plaintiff is not required to partake in any recovery. CONTACT US HERE: https://securitiesclasslaw.com/securities/edwards-lifesciences-loss-submission-form/?id=113425&from=3 CLASS PERIOD: February 6, 2024 to July 24, 2024 ALLEGATIONS: According to the complaint, defendants provided investors with material information concerning Edwards’ expected revenue for the fiscal year 2024, particularly as it related to the growth of the Company’s core product, Transcatheter Aortic Valve Replacement (“TAVR”). Defendants’ statements included, among other things, strong commitment to the TAVR platform, confidence in the Company’s ability to capitalize on a subset of untreated patients through scaling of its various patient activation activities, and continued claims of significant demand in allegedly lower-penetrated markets. On July 24, 2024, Edwards unveiled below-expectation financial results for the second quarter of fiscal 2024 and, in particular, slashed its revenue guidance for the TAVR platform for the full fiscal year 2024. The Company attributed the TAVR setback on the “continued growth and expansion of structural heart therapies ... [which] put pressure on hospital workflows.” Investors understood this to mean that developments in new procedures, including defendant’s own Transcatheter Mitral and Tricuspid Therapies (“TMTT”), put significant strain on hospital structural heart teams such that they were underutilizing TAVR, despite the Company’s continued claim of a significantly undertreated patient population. Moreover, the Company announced three acquisitions during the second quarter designed to embolden their treatments alternative to TAVR, suggesting further that the company was aware of the potential for the TAVR platform’s decelerated growth. Investors and analysts reacted immediately to Edwards’ revelations. The price of Edwards’ common stock declined dramatically. From a closing market price of $86.95 per share on July 24, 2024, Edwards’ stock price fell to $59.70 per share on July 25, 2024, a decline of about 31.34% in the span of just a single day. DEADLINE: December 13, 2024 Shareholders should not delay in registering for this class action. Register your information here: https://securitiesclasslaw.com/securities/edwards-lifesciences-loss-submission-form/?id=113425&from=3 NEXT STEPS FOR SHAREHOLDERS: Once you register as a shareholder who purchased shares of EW during the timeframe listed above, you will be enrolled in a portfolio monitoring software to provide you with status updates throughout the lifecycle of the case. The deadline to seek to be a lead plaintiff is December 13, 2024. There is no cost or obligation to you to participate in this case. WHY GROSS LAW FIRM? The Gross Law Firm is a nationally recognized class action law firm, and our mission is to protect the rights of all investors who have suffered as a result of deceit, fraud, and illegal business practices. The Gross Law Firm is committed to ensuring that companies adhere to responsible business practices and engage in good corporate citizenship. The firm seeks recovery on behalf of investors who incurred losses when false and/or misleading statements or the omission of material information by a company lead to artificial inflation of the company's stock. Attorney advertising. Prior results do not guarantee similar outcomes. CONTACT: The Gross Law Firm 15 West 38th Street, 12th floor New York, NY, 10018 Email: dg@securitiesclasslaw.com Phone: (646) 453-8903Two of Pa. Rep. Summer Lee's closest allies lost reelection bids. What could it spell for her future?
BOSTON , Dec. 13, 2024 /PRNewswire/ -- The Board of Directors (the "Board") of The China Fund, Inc. (the "Fund") has declared a distribution in the amount of $0.1497 per share. The distribution is comprised entirely of ordinary income. The dividend will be payable on January 10, 2025 , to stockholders of record on December 30, 2024 , with an ex-dividend date of December 30, 2024 . The Fund has a Dividend Reinvestment and Cash Purchase Plan (the "Plan") in which each stockholder automatically participates, unless the stockholder instructs Computershare Trust Company, N.A. (the "Plan Agent"), in writing, to have all distributions, net of any applicable U.S. withholding tax, paid in cash. If the Fund's shares are trading at a premium to the net asset value ("NAV") per share of the Fund on the distribution payment date, the Plan provides that stockholders will be issued Fund shares valued at NAV. If the Fund's shares are trading at a discount to the NAV per share, stockholders will be issued shares of the Fund valued at market price. Stockholders will not be charged a fee in connection with the reinvestment of dividends or capital gains distributions. A stockholder may terminate his or her participation in the Plan by notifying the Plan Agent in writing at the address below. Stockholders who have questions regarding the distribution may contact EQ Fund Solutions, LLC at 1-888-CHN-CALL (246-2255). The Fund is a closed-end management investment company with the objective of seeking long-term capital appreciation by investing primarily in equity securities (i) of companies for which the principal securities trading market is in the People's Republic of China (" China "), or (ii) of companies for which the principal securities trading market is outside of China , or constituting direct equity investments in companies organized outside of China , that in both cases derive at least 50% of their revenues from goods and services sold or produced, or have at least 50% of their assets, in China . While the Fund is permitted to invest in direct equity investments of companies organized in China , it presently holds no such investments. The Fund's shares are listed on the New York Stock Exchange under the ticker symbol "CHN." The Fund's investment manager is Matthews International Capital Management, LLC. For more information regarding the Fund and the Fund's holdings, please call 1-888-CHN-CALL (246-2255) or visit the Fund's website at www.chinafundinc.com . For more information about the Plan or to terminate your participation in the Plan, please contact Computershare Trust Company, N.A. at c/o The China Fund, Inc. at P.O. Box 43078, Providence, Rhode Island 02940-3078, by telephone at 1-800-426-5523 or via the Internet at www.computershare.com/investor . View original content: https://www.prnewswire.com/news-releases/the-china-fund-inc-declares-distributions-302331625.html SOURCE The China Fund, Inc.
By MICHAEL R. SISAK and JENNIFER PELTZ NEW YORK (AP) — President-elect Donald Trump’s lawyers urged a judge again Friday to throw out his hush money conviction, balking at the prosecution’s suggestion of preserving the verdict by treating the case the way some courts do when a defendant dies. They called the idea “absurd.” Related Articles National Politics | Trump wants to turn the clock on daylight saving time National Politics | Ruling by a conservative Supreme Court could help blue states resist Trump policies National Politics | A nonprofit leader, a social worker: Here are the stories of the people on Biden’s clemency list National Politics | Nancy Pelosi hospitalized after she ‘sustained an injury’ on official trip to Luxembourg National Politics | Veteran Daniel Penny, acquitted in NYC subway chokehold, will join Trump’s suite at football game The Manhattan district attorney’s office is asking Judge Juan M. Merchan to “pretend as if one of the assassination attempts against President Trump had been successful,” Trump’s lawyers wrote in a blistering 23-page response. In court papers made public Tuesday, District Attorney Alvin Bragg’s office proposed an array of options for keeping the historic conviction on the books after Trump’s lawyers filed paperwork earlier this month asking for the case to be dismissed. They include freezing the case until Trump leaves office in 2029, agreeing that any future sentence won’t include jail time, or closing the case by noting he was convicted but that he wasn’t sentenced and his appeal wasn’t resolved because of presidential immunity. Trump lawyers Todd Blanche and Emil Bove reiterated Friday their position that the only acceptable option is overturning his conviction and dismissing his indictment, writing that anything less will interfere with the transition process and his ability to lead the country. The Manhattan district attorney’s office declined comment. It’s unclear how soon Merchan will decide. He could grant Trump’s request for dismissal, go with one of the prosecution’s suggestions, wait until a federal appeals court rules on Trump’s parallel effort to get the case moved out of state court, or choose some other option. In their response Friday, Blanche and Bove ripped each of the prosecution’s suggestions. Halting the case until Trump leaves office would force the incoming president to govern while facing the “ongoing threat” that he’ll be sentenced to imprisonment, fines or other punishment as soon as his term ends, Blanche and Bove wrote. Trump, a Republican, takes office Jan. 20. “To be clear, President Trump will never deviate from the public interest in response to these thuggish tactics,” the defense lawyers wrote. “However, the threat itself is unconstitutional.” The prosecution’s suggestion that Merchan could mitigate those concerns by promising not to sentence Trump to jail time on presidential immunity grounds is also a non-starter, Blanche and Bove wrote. The immunity statute requires dropping the case, not merely limiting sentencing options, they argued. Blanche and Bove, both of whom Trump has tabbed for high-ranking Justice Department positions, expressed outrage at the prosecution’s novel suggestion that Merchan borrow from Alabama and other states and treat the case as if Trump had died. Blanche and Bove accused prosecutors of ignoring New York precedent and attempting to “fabricate” a solution “based on an extremely troubling and irresponsible analogy between President Trump” who survived assassination attempts in Pennsylvania in July and Florida in September “and a hypothetical dead defendant.” Such an option normally comes into play when a defendant dies after being convicted but before appeals are exhausted. It is unclear whether it is viable under New York law, but prosecutors suggested that Merchan could innovate in what’s already a unique case. “This remedy would prevent defendant from being burdened during his presidency by an ongoing criminal proceeding,” prosecutors wrote in their filing this week. But at the same time, it wouldn’t “precipitously discard” the “meaningful fact that defendant was indicted and found guilty by a jury of his peers.” Prosecutors acknowledged that “presidential immunity requires accommodation” during Trump’s impending return to the White House but argued that his election to a second term should not upend the jury’s verdict, which came when he was out of office. Longstanding Justice Department policy says sitting presidents cannot face criminal prosecution . Other world leaders don’t enjoy the same protection. For example, Israeli Prime Minister Benjamin Netanyahu is on trial on corruption charges even as he leads that nation’s wars in Lebanon and Gaza . Trump has been fighting for months to reverse his May 30 conviction on 34 counts of falsifying business records . Prosecutors said he fudged the documents to conceal a $130,000 payment to porn actor Stormy Daniels to suppress her claim that they had sex a decade earlier, which Trump denies. In their filing Friday, Trump’s lawyers citing a social media post in which Sen. John Fetterman used profane language to criticize Trump’s hush money prosecution. The Pennsylvania Democrat suggested that Trump deserved a pardon, comparing his case to that of President Joe Biden’s pardoned son Hunter Biden, who had been convicted of tax and gun charges . “Weaponizing the judiciary for blatant, partisan gain diminishes the collective faith in our institutions and sows further division,” Fetterman wrote Wednesday on Truth Social. Trump’s hush money conviction was in state court, meaning a presidential pardon — issued by Biden or himself when he takes office — would not apply to the case. Presidential pardons only apply to federal crimes. Since the election, special counsel Jack Smith has ended his two federal cases , which pertained to Trump’s efforts to overturn his 2020 election loss and allegations that he hoarded classified documents at his Mar-a-Lago estate. A separate state election interference case in Fulton County, Georgia, is largely on hold. Trump denies wrongdoing in all. Trump had been scheduled for sentencing in the hush money case in late November. But following Trump’s Nov. 5 election victory, Merchan halted proceedings and indefinitely postponed the former and future president’s sentencing so the defense and prosecution could weigh in on the future of the case. Merchan also delayed a decision on Trump’s prior bid to dismiss the case on immunity grounds. A dismissal would erase Trump’s conviction, sparing him the cloud of a criminal record and possible prison sentence. Trump is the first former president to be convicted of a crime and the first convicted criminal to be elected to the office.
King laughs at British comedian’s impression of Donald Trump at Royal VarietyNEWARK, N.J. (AP) — Emerance Maschmeyer turned in 34 saves on 35 shots on goal and the Ottawa Charge held off the New York Sirens 3-1 on Sunday for their second win in six games. Playing their first game in 10 days, the Charge got a first-period goal from Emily Clark and Shiann Darkangelo and Kateřina Mrázová added second-period goals to build a 3-0 lead through two periods. Ottawa has scored at least three goals in all five of its meetings with New York over two seasons. Alex Carpenter earned a third-period assist to extend her scoring streak to nine straight games dating to last season. Sarah Fillier's goal moved her into a tie for the league lead with eight points in her first eight games after being drafted No. 1 by the Sirens. Ottawa's defense neutralized much of New York's speed advantage and used a strong penalty kill to take a 1-0 lead after one period after Clark tipped home a wrist shot from the point by Brianne Jenner six minutes into the game. The Charge added two goals in the first seven minutes of the second period but could not capitalize on a pair of power plays late in the period. Fillier wasted little time getting New York on the board in the third period, firing a shot past Maschmeyer 23 seconds into the period, but the keeper saved the next dozen shots, including an almost three-minute finish when the Sirens pulled goalkeeper Corinne Schroeder to gain a player advantage. New York's Jill Saulnier was activated off long-term injured reserve following an upper body injury sustained in the opening game December 1. ___ AP hockey: https://apnews.com/hub/hockey The Associated Press
Final crystal triangles installed on Times Square ball ahead of New Year's EveWASHINGTON (AP) — Former House Speaker Nancy Pelosi has been hospitalized after she “sustained an injury” during an official engagement in Luxembourg, according to a spokesman. Pelosi, 84, was in Europe with a bipartisan congressional delegation to mark the 80th anniversary of the Battle of the Bulge in World War II . Her spokesman, Ian Krager, said in a statement that she is “currently receiving excellent treatment from doctors and medical professionals” and is unable to attend the remainder of events on her trip. He did not describe the nature of her injury or give any additional details, but a person familiar with the incident said that Pelosi tripped and fell while at an event with the other members of Congress. The person requested anonymity to discuss the fall because they were not authorized to speak about it publicly. Krager said that Pelosi “looks forward to returning home to the U.S. soon." Among the members on the trip was Rep. Michael McCaul , R-Texas, who posted on social media that he was “praying for a speedy recovery,” for Pelosi. The two lawmakers were captured holding hands in a group photo Friday at the U.S. Embassy in Luxembourg. “I’m disappointed Speaker Emerita Pelosi won’t be able to join the rest of our delegation’s events this weekend as I know how much she looked forward to honoring our veterans,” McCaul wrote on X. “But she is strong, and I am confident she will be back on her feet in no time.” The former leader's fall comes two years after her husband Paul was attacked by a man with a hammer at their San Francisco home. The man, who was sentenced in October to 30 years in federal prison, broke into their home looking for Pelosi. Pelosi, who was first elected in 1987 and served as speaker twice, stepped down from her leadership post two years ago but remained in Congress and was re-elected to represent her San Francisco district in November. She has remained active in the two years since she left the top job, working with Democrats in private and in public and attending official events. Last summer, she was instrumental in her party's behind the scenes push to urge President Joe Biden to leave the presidential ticket. She attended the Kennedy Center Honors in Washington last weekend and was on the Senate floor Monday to attend the swearing in of her former Democratic House colleagues, Adam Schiff of California and Andy Kim of New Jersey. Earlier this week, Senate Republican Leader Mitch McConnell , 82, tripped and fell in the Senate , spraining his wrist and cutting his face. McConnell, who is stepping down from his leadership post at the end of the year, missed Senate votes on Thursday after experiencing some stiffness in his leg from the fall, his office said.
Police hunt for UnitedHealthcare CEO's masked killer after 'brazen, targeted' attack on NYC street NEW YORK (AP) — UnitedHealthcare’s CEO has been shot and killed in what police say is a “brazen, targeted attack” outside a Manhattan hotel where the health insurer was holding its investor conference. The shooting rattled the city and set off a massive dragnet hours before the annual Rockefeller Center Christmas tree lighting. Police say 50-year-old Brian Thompson was shot around 6:45 a.m. Wednesday as he walked alone to the New York Hilton Midtown from a nearby hotel. New York City Police Commissioner Jessica Tisch says the shooter appeared to be “lying in wait for several minutes” before approaching Thompson from behind and opening fire. Police have not yet established a motive. UnitedHealthcare CEO kept a low public profile. Then he was shot to death in New York NEW YORK (AP) — Brian Thompson led one of the biggest health insurers in the US but was unknown to millions of people his decisions affected. The fatal shooting of UnitedHealthcare's chief executive on a midtown Manhattan sidewalk Wednesday became a mystery that riveted the nation. Police say it was a targeted killing. Thompson was 50. He had worked at the company for 20 years and had run health care giant UnitedHealth Group Inc.'s insurance business since 2021. It provides health coverage for more than 49 million Americans and brought in $281 billion in revenue last year. Thompson's $10.2 million annual compensation made him one of the company’s highest-paid executives. Supreme Court seems likely to uphold Tennessee's ban on medical treatments for transgender minors WASHINGTON (AP) — Hearing a high-profile culture-war clash, the Supreme Court on Wednesday seemed likely to uphold Tennessee’s ban on gender-affirming care for minors. The justices’ decision, not expected for several months, could affect similar laws enacted by another 25 states and a range of other efforts to regulate the lives of transgender people, including which sports competitions they can join and which bathrooms they can use. The case is being weighed by a conservative-dominated court after a presidential election in which Donald Trump and his allies promised to roll back protections for transgender people. The Biden administration’s top Supreme Court lawyer warned a decision favorable to Tennessee also could be used to justify nationwide restrictions on transgender healthcare for minors. Hegseth fights to save Pentagon nomination as sources say Trump considers DeSantis WASHINGTON (AP) — Pete Hegseth, Donald Trump’s Pentagon pick, is fighting to hold on to his Cabinet nomination amid growing questions about his personal conduct as the president-elect’s team considers alternatives, including Florida Gov. Ron DeSantis. But Hegseth says, “We’re not backing down one bit." The Trump transition team is concerned about Hegseth’s path to Senate confirmation and is actively looking at potential replacements, according to a person familiar with the matter. Hegseth is under pressure as senators weigh a series of allegations that have surfaced against him. Beyond DeSantis, there have been discussions about shifting Michael Waltz, who was named by Trump as his national security adviser, to the Defense Department Israeli strikes on a Gaza tent camp kill at least 21 people, hospital says KHAN YOUNIS, Gaza Strip (AP) — A Palestinian health official said Wednesday that at least 21 people were killed in Israeli strikes on a camp housing displaced people in Gaza. The Israeli military said it struck senior Hamas militants. The strikes hit in the Muwasi area, a sprawling coastal camp housing hundreds of thousands of displaced people. It came after Israeli forces struck targets in other areas of Gaza. According to Palestinian medics, strikes in central Gaza killed eight people, including four children. The war in Gaza is nearly 14 months old and showing no end in sight, despite international efforts to revive negotiations toward a ceasefire. South Korean President Yoon's martial law declaration raises questions over his political future SEOUL, South Korea (AP) — President Yoon Suk Yeol’s stunning martial law declaration lasted just hours, but experts say it raised serious questions about his ability to govern for the remaining 2 1/2 years of his term. The opposition-controlled parliament overturned the edict, and his rivals on Wednesday took steps to impeach him. Yoon's move baffled many experts. One analyst called his action “political suicide.” Yoon’s political fate may depend on whether a large number of people in coming days take to the streets to push for his ouster. Yoon hasn't commented on the impeachment bid. But the political instability he unleashed could make it more difficult for his government to nurse a decaying economy. Police say searchers don’t expect to find woman in Pennsylvania sinkhole alive UNITY TOWNSHIP, Pa. (AP) — The search for a woman who is believed to have fallen into a sinkhole in western Pennsylvania has become a recovery effort after two treacherous days of digging through mud and rock produced no signs of life. Pennsylvania State Police spokesperson Trooper Steve Limani said during a news conference Wednesday that authorities no longer believe they will find 64-year-old Elizabeth Pollard alive, but that the search for her remains continues. Limani says crews have seen "no signs of any form of life or anything.” Pollard was last seen alive Monday evening when she went out looking for her cat in the village of Marguerite, about 40 miles east of Pittsburgh. Two children wounded and gunman dead after shooting at Northern California school PALERMO, Calif. (AP) — Sheriff’s officials say two children have been wounded in a shooting at a small religious school in Northern California and the gunman is dead. A Butte County Sheriff’s Office spokesperson says Wednesday the wounded students were taken to hospitals in unknown condition after the shooting at Feather River School of Seventh-Day Adventists in Palermo, north of Sacramento. The spokesperson says the suspect died after apparently shooting himself. A motive is unknown. French lawmakers vote to oust prime minister in the first successful no-confidence vote since 1962 PARIS (AP) — France’s far-right and left-wing lawmakers have joined together to vote on a no-confidence motion prompted by budget disputes that forces Prime Minister Michel Barnier and his Cabinet to resign. The National Assembly approved the motion by 331 votes. A minimum of 288 were needed. President Emmanuel Macron insisted he will serve the rest of his term until 2027. However, he will need to appoint a new prime minister for the second time after July’s legislative elections led to a deeply divided parliament. Macron will address the French on Thursday evening, his office said, without providing details. Barnier is expected to formally resign by then. White House says at least 8 US telecom firms, dozens of nations impacted by China hacking campaign WASHINGTON (AP) — A top White House official says at least eight U.S. telecom firms and dozens of nations have been impacted by a Chinese hacking campaign. Deputy national security adviser Anne Neuberger offered the new details Wednesday about the breadth of the sprawling Chinese hacking campaign that gave officials in Beijing access to private texts and phone conversations of an unknown number of Americans. Neuberger divulged the scope of the hack a day after the FBI and the Cybersecurity and Infrastructure Security Agency issued guidance intended to help root out the hackers and prevent similar cyberespionage in the future. White House officials cautioned that a number of telecommunication firms and countries impacted could still grow.
NoneDemocrat Bob Casey concedes to Republican David McCormick in Pennsylvania Senate contestPPG today announced its 50th order for the electrostatic application of marine fouling control coatings. The project will be carried out on the VLCC SIDR, a 336-meter oil tanker operated by Bahri Ship Management at the Asyad Drydock Company shipyard in Oman, using PPG NEXEONTM 810 antifouling coating on the hull. Leveraging decades of experience in the aerospace and automotive industries, PPG introduced electrostatic coating application to the shipping industry just over a year ago. Electrostatic application provides an increased transfer efficiency compared to airless spraying, resulting in sustainability benefits including significant reductions in overspray and waste. PPG has optimized its hull coatings for this application technique. PPG books 50th vessel using electrostatic coating application “Ship owners and shipyards are looking for innovative solutions to comply with stricter environmental regulations and meet their sustainability goals – these include low-friction hull coatings that reduce vessel greenhouse gas emissions and provide sustainably advantaged application procedures,” said Sijmen Visser, PPG sales director, Marine EMEA, Protective and Marine Coatings. “Electrostatic application is quickly being adopted by large shipping companies and by shipyards in Europe, Singapore and China.” Conventional fouling control coatings are generally not suitable for electrostatic application. However, the formulation of both PPG Nexeon antifouling and PPG SIGMAGLIDE® fouling release coatings allow them to be sprayed electrostatically. Electrically charged paint particles are precisely guided towards the grounded surface of the vessel, leading to an exceptionally even distribution and the formation of a uniform and ultrasmooth, long-lasting film layer. “We strive to conduct our business in a sustainable way and constantly measure our environmental impact through performance indicators,” said Khalid Alhammad, Ship Management President at Bahri. “A cornerstone of our environmental strategy is to reduce carbon emissions of our entire fleet. To achieve these objectives, we constantly adopt the latest technologies in hull coating that would help reduce vessel emissions. Combining that with a sustainable coating application technique makes it an attractive combination to us.” Electrostatic application of PPG hull coatings In a recent project, EDR Antwerp shipyard confirmed a 40 per cent reduction in overspray with the electrostatic application of PPG Sigmaglide coating on a RoRo passenger vessel from Stena Line. With reduced overspray, electrostatic application provides a cleaner operation and improved work environment for the applicators compared to airless spraying. Shipyards spend less time masking the vessel and cleaning the dock, saving time and costs. Source: PPG
The only shop in one of the smallest villages in the country is closing its doors for the last time ever tomorrow, its owners have confirmed. Phillip Payne and his wife Lucy have run Mersham Stores and Post Office in Mersham, near Ashford, Kent , for more than eight years - but have been unable to renew their lease on the property, meaning the shop will cease to trade as of midday on Sunday. The shop owners said they are "devastated" to close the store which has become a "big part of the community" in the little village. The couple are now planning to move to Yorkshire and take over another village shop there. However, Mr Payne said both he and his wife are "incredibly sad" to leave Mersham. The 51-year-old told Kent Online : "It's not something we wanted to do, but we haven't been able to renew the lease. We have loved our time in the village and have had such a great relationship with our customers. "We're just truly grateful for everybody who has supported us over the years." Addressing the decision to move to Yorkshire, Mr Payne said: "We are opening a small village shop in the Yorkshire Dales and hope to replicate what we built here in Kent. I want to thank all of our amazing customers. We are really going to miss them. It's been a privilege to be a part of this community." Shoppers have also been left disappointed at the news, as one wrote: "Very sad to read this. Such a wonderful shop and very lovely people. All the best for the future." Another added: "Sadly the loss of village shops in traditional small villages has been the downfall of community life in such places. "The village shop is where people passed the time of day, people got to know any new neighbours and they were a lifeline for older people who couldn't access larger shops in towns or just wanted to get out and have a chat with someone. Now villages without shops are just somewhere to live; inhabitants go to work and come home, go elsewhere for their shopping and probably don't have much to do with other villagers; other than their immediate neighbours (if that)." It is believed the owner of the building is now looking for alternative tenants to take on the shop, after Ashford Borough Council (ABC) listed the store as an asset of community value (ACV) last month. An ACV is a building or other land whose "main use has recently been or is presently used to further the social wellbeing or social interests of the local community and could do so in the future." The move allows community groups to protect assets from being sold to private owners - and if the owner of the building wants to sell, they need to notify the local authority.The city’s disgraced ex-buildings commissioner is striking out again. Months after admitting he couldn’t afford a lawyer in his political bribery case, Eric Ulrich desperately auctioned off his beloved 1958 Mickey Mantle baseball card. But all he collected was $55 — minus a 10% donation to St. Jude’s Research Hospital and $14 in fees — leaving him with about enough cash to buy a hot dog and beer at Yankee Stadium. He put his beaten-up, 66-year-old Topps All-Star Card #487 on eBay two months after he asked a Manhattan Supreme Court judge to appoint him a taxpayer-funded attorney. “This is a rare 1958 Topps trading card featuring baseball legend Mickey Mantle in his All Star uniform,” Ulrich trumpeted on the auction page. “The card is well-preserved and is a great addition to any collection. It is ungraded, but its value is undeniable.” Mint condition versions of the card, which features the Mick on a red background with white stars, have gone for as much as $9,900 at auction, but experts said Ulrich’s collectible was not ready for the majors. “It has ... two print roller lines, one right across the face, which is a major detriment to the eye appeal, and a more faint one across its knees,” Jacob Salter, a buyer at Bleecker Trading in Manhattan, told The Post after reviewing the auction images. “We’d expect that card to go between $50 and $70, based on historical sales.” Critics relished the news that the Queens pol is now auctioning off mementos amid mounting legal fees, having previously turned to hawking insurance policies to pay his bills. “Eric Ulrich is just striking out like his entire political career,” said Gavin Mario Wax, president of the New York Young Republicans Club. “Being forced to sell baseball cards is a fitting end to [his] corrupt, contemptible blight on the Republican Party.” One Queens political insider suggested Ulrich likely earned more from the auction than sales of a children’s book he self-published in September 2023, which imagined dogs serving as judges and jurors and a chameleon as a city council member. “It’s still $55 more than he made from his book sales,” the person quipped. Later that month, the Manhattan DA’s office indicted Ulrich on 16 felony corruption charges, alleging he traded political favors as far back as his City Council days for $150,000 in cash and gifts, including a bespoke suit and Mets season tickets. The former Buildings honcho was subsequently slapped with a $150 million civil suit in September by Runway Towing, which alleged Ulrich took bribes from a rival company’s owner, who was also indicted last year. Runway claims that in exchange for the gifts, Ulrich pressured the Department of Consumer and Worker Protection to axe its lucrative city contracts and operating license. Ulrich, who has pleaded not guilty to the charges, insisted the auction had “nothing” to do with his financial straits and motivated solely by a desire to support St. Jude’s. “During the holiday season, we can all find ways to give to charities that help those in need,” he said. “I have other collectible items that I may auction off in the future and absolutely will be donating some of the funds received to a worthy cause.”
Our victory in Maharashtra defeat of family raaj: BJP
SCOTTSDALE, Ariz. — Even when Penn State quarterback Drew Allar gets some praise, it's usually a backhanded compliment. They say he's a good game manager and stays within himself, or that he doesn't try to do too much. They mention he might not be flashy, but he gives the team a chance to win. And here's the thing about Penn State since Allar stepped under center: The Nittany Lions have won games. A lot of them. Sometimes that's hard to remember considering the lukewarm reception he often gets from fans. "I get it — we have a really passionate fan base and they're a huge part of our success," Allar said Sunday at College Football Playoff quarterfinals media day. "For us, we always want to go out there every drive and end with a touchdown, so when we don't do that, there's nobody more frustrated than us." The polarizing Allar is having a solid season by just about any standard, completing more than 68% of his passes for 3,021 yards, 21 touchdowns and seven interceptions while leading the sixth-seeded Nittany Lions to a 12-2 record and a spot in the Fiesta Bowl for Tuesday's game against No. 3 seed Boise State. People are also reading... But in a college football world filled with high-scoring, explosive offenses, Allar's no-frills performances often are the object of ire. The Penn State offense is a run-first bunch, led by the talented combo of Nicholas Singleton and Kaytron Allen. "If we had a nickel for every time there was a Monday morning quarterback saying some BS stuff, we'd all be pretty rich," offensive coordinator Andy Kotelnicki said. "I think part of being a quarterback, especially at Penn State but really anywhere, is how you respond to and manage criticism." The 20-year-old Allar has made strides in that department after a trying 2023 season that finished with a 10-3 record. He says that's largely because once fall camp started back in August, he logged off the social media platform X. Allar said negative online experiences wore on him last year, and his phone number was leaked a few times, which added to the stress. He finally realized that controlling outside narratives was impossible, so the best course of action was to eliminate a needless distraction. "I've been more mentally free, as much as that sounds crazy," Allar said. "I think that's been a huge difference for me this year." The biggest criticism of Allar — and really Penn State as a whole during the 11-year James Franklin era — is that he isn't capable of winning the big games. He's 0-2 against rival Ohio State and threw a late interception against Oregon in the Big Ten title game earlier this month, which sealed the Ducks' 45-37 victory. He wasn't great in the CFP's first round, either, completing just 13 of 22 passes for 127 yards as Penn State muscled past SMU 38-10 on a cold, blustery day to advance to the Fiesta Bowl. But the quarterback is confident a better performance — aided by a game that will be played in comfortable temperatures in a domed stadium — is coming. "For me, I just have to execute those (easy) throws early in the game and get our guys into rhythm," Allar said. "Get them involved early as much as I can and that allows us to stay on the field longer, call more plays and open up our offense more. That will help us a ton, building the momentum throughout the game." Allar might be a favorite punching bag for a section of the Penn State fan base, but that's not the case in his own locker room. Star tight end Tyler Warren praised his quarterback's ability to avoid sacks, saying that the 6-foot-5, 238-pounder brings a toughness that resonates with teammates. "He's a football player," Warren said. "He plays quarterback, but when you watch him play and the energy he brings and the way he runs the ball, he's just a football player and that fires up our offense." Now Allar and Penn State have a chance to silence critics who say that the Nittany Lions don't show up in big games. Not that he's worried about what other people think. "I think it's a skill at the end of the day — blocking out the outside noise," Allar said. "Focusing on you and the process and being honest with yourself, both good and bad." Be the first to know Get local news delivered to your inbox!Stock market update: Fertilisers stocks up as market falls
Wall Street stocks finished a lackluster week on a muted note Friday as concerns about rising Treasury bond yields competed with enthusiasm over artificial intelligence equities. Of the major indices, only the Nasdaq mustered a gain in Friday's session. The tech-rich index was also the only of the three leading US benchmarks to conclude the week higher. "Equities are kind of treading water," said LBBW's Karl Haeling. "A negative influence to some extent is the rise in bond yields." The latest US consumer price index data released this week showed prices ticked higher in November and the wholesale data also showed stubborn inflationary pressures. "Yields rose to their highest levels in over two weeks as markets brace for the Federal Reserve's final meeting of the year, reflecting concerns over sticky inflation," said Chris Beauchamp, chief market analyst at online trading platform IG. There is also growing concern over the inflationary pressures from President-elect Donald Trump's pledges to cut taxes and impose tariffs, as inflation still stands above the Fed's target. "While the markets still anticipate a rate cut from the Federal Reserve next week, the likelihood of a move in January has dropped," said Patrick Munnelly, partner at broker Tickmill Group. The CME FedWatch tool shows the market sees a more than 75 percent chance that the Fed will hold rates steady in January. In Europe, the Paris CAC 40 index ended the day down 0.2 percent after French President Emmanuel Macron named his centrist ally Francois Bayrou as prime minister, ending days of deadlock over finding a replacement for Michel Barnier. Frankfurt also dipped, with Germany's central bank sharply downgrading its growth forecasts on Friday for 2025 and 2026. It predicted a prolonged period of weakness for Europe's biggest economy. London stocks were also lower after official data showed that the UK economy unexpectedly shrank for the second consecutive month in October. The euro recovered after flirting with two-year lows against the dollar following a warning Thursday by ECB president Christine Lagarde that the eurozone economy was "losing momentum", cautioning that "the risk of greater friction in global trade could weigh on euro area growth". In Asia, Hong Kong and Shanghai both tumbled as investors were unimpressed with Beijing's pledge to introduce measures aimed at "lifting consumption vigorously" as part of a drive to reignite growth in the world's number two economy. President Xi Jinping and other key leaders said at the annual Central Economic Work Conference they would implement a "moderately loose" monetary policy, increase social financing and reducing interest rates "at the right time". The gathering came after Beijing in September began unveiling a raft of policies to reverse a growth slump that has gripped the economy for almost two years. "We're still not convinced that policy support will prevent the economy from slowing further next year", said Julian Evans-Pritchard, head of China economics at research group Capital Economics. Among individual equities, chip company Broadcom surged nearly 25 percent after reporting a 51 percent jump in quarterly revenues to $14.1 billion behind massive growth in AI-linked business. New York - Dow: DOWN 0.2 percent at 43,828.06 (close) New York - S&P 500: FLAT at 6,051.09 (close) New York - Nasdaq Composite: UP 0.1 percent at 19,926.72 (close) London - FTSE 100: DOWN 0.1 percent at 8,300.33 (close) Paris - CAC 40: DOWN 0.2 percent at 7,409.57 (close) Frankfurt - DAX: DOWN 0.1 percent at 20,405.92 (close) Tokyo - Nikkei 225: DOWN 1.0 percent at 39,470.44 (close) Hong Kong - Hang Seng Index: DOWN 2.1 percent at 19,971.24 (close) Shanghai - Composite: DOWN 2.0 percent at 3,391.88 (close) Euro/dollar: UP at $1.0504 from $1.0467 on Thursday Pound/dollar: DOWN at $1.2622 from $1.2673 Dollar/yen: UP at 153.60 yen from 152.63 yen Euro/pound: UP at 83.19 pence from 82.59 pence Brent North Sea Crude: UP 1.5 percent at $74.49 per barrel West Texas Intermediate: UP 1.8 percent at $71.29 per barrel burs-jmb/stTOKYO and CAMBRIDGE, Mass. , Dec. 4, 2024 /PRNewswire/ -- Eisai Co., Ltd. (Headquarters: Tokyo , CEO: Haruo Naito , "Eisai") and Biogen Inc. (Nasdaq: BIIB, Corporate headquarters: Cambridge, Massachusetts , CEO: Christopher A. Viehbacher , "Biogen") announced today that the Federal Commission for the Protection Against Sanitary Risk (COFEPRIS) in Mexico has approved humanized anti-soluble aggregated amyloid-beta (Aβ) monoclonal antibody "LEQEMBI ® " (lecanemab) for the treatment of early Alzheimer's disease (AD)*. LEQEMBI selectively binds to soluble Aβ aggregates (protofibrils**), as well as insoluble Aβ aggregates (fibrils) which are a major component of Aβ plaques, thereby reducing both Aβ protofibrils and Aβ plaques in the brain. LEQEMBI is the first approved treatment shown to reduce the rate of disease progression and to slow cognitive and functional decline through this mechanism. LEQEMBI is also approved and being marketed in the U.S., Japan , China , South Korea , Hong Kong , Israel , the United Arab Emirates, and Great Britain . LEQEMBI's approval is based on the large global Phase 3 Clarity AD study. In the Clarity AD study, LEQEMBI met its primary endpoint and all key secondary endpoints with statistically significant results. 1,2 Approximately 1.3 million people in Mexico are estimated to suffer from AD, accounting for 60-70% of all dementia diagnoses. 3 AD most commonly affects individuals over the age of 65. 3 Eisai serves as the lead of LEQEMBI development and regulatory submissions globally with both Eisai and Biogen co-commercializing and co-promoting the product and Eisai having final decision-making authority. Eisai and Biogen will co-commercialize and co-promote LEQEMBI in Mexico . * Collectively referred to mild cognitive impairment due to AD or mild AD dementia. ** Protofibrils are believed to contribute to the brain injury that occurs with AD and are considered to be the most toxic form of Aβ, having a primary role in the cognitive decline associated with this progressive, debilitating condition. 4 Protofibrils cause injury to neurons in the brain, which in turn, can negatively impact cognitive function via multiple mechanisms, not only increasing the development of insoluble Aβ plaques but also increasing direct damage to brain cell membranes and the connections that transmit signals between nerve cells or nerve cells and other cells. It is believed the reduction of protofibrils may prevent the progression of AD by reducing damage to neurons in the brain and cognitive dysfunction. 5 Notes to Editors 1. About lecanemab (LEQEMBI ® ) Lecanemab is the result of a strategic research alliance between Eisai and BioArctic. It is a humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble (protofibril) and insoluble forms of amyloid-beta (Aβ). Lecanemab is approved and being marketed in the U.S., Japan , China , South Korea , Hong Kong , Israel , the United Arab Emirates and Great Britain for the treatment of Alzheimer's disease (AD) in patients with Mild Cognitive Impairment (MCI) or mild dementia stage of disease (collectively referred to as early AD). The treatment's approvals in these countries was based on Phase 3 data from Eisai's global Clarity AD clinical trial, in which it met its primary endpoint and all key secondary endpoints with statistically significant results. 1,2 The most common adverse events (>10%) in the lecanemab group were infusion reactions, ARIA-H (combined cerebral microhemorrhages, cerebral macrohemorrhages, and superficial siderosis), ARIA-E (edema/effusion), headache, and fall. Lecanemab is under regulatory review in 16 countries and regions, including the European Union. In November 2024 , the treatment received a positive opinion from the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) recommending approval. Since July 2020 the Phase 3 clinical study (AHEAD 3-45) for individuals with preclinical AD, meaning they are clinically normal and have intermediate or elevated levels of amyloid in their brains, is ongoing. AHEAD 3-45 is conducted as a public-private partnership between the Alzheimer's Clinical Trial Consortium that provides the infrastructure for academic clinical trials in AD and related dementias in the U.S, funded by the National Institute on Aging, part of the National Institutes of Health, Eisai and Biogen. Since January 2022 , the Tau NexGen clinical study for Dominantly Inherited AD (DIAD), that is conducted by Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU), led by Washington University School of Medicine in St. Louis , is ongoing and includes lecanemab as the backbone anti-amyloid therapy. 2. About the Collaboration between Eisai and Biogen for AD Eisai and Biogen have been collaborating on the joint development and commercialization of AD treatments since 2014. Eisai serves as the lead of lecanemab development and regulatory submissions globally with Eisai and Biogen co-commercializing and co-promoting the product and Eisai having final decision-making authority. 3. About the Collaboration between Eisai and BioArctic for AD Since 2005, Eisai and BioArctic have had a long-term collaboration regarding the development and commercialization of AD treatments. Eisai obtained the global rights to study, develop, manufacture and market lecanemab for the treatment of AD pursuant to an agreement with BioArctic in December 2007 . The development and commercialization agreement on the antibody lecanemab back-up was signed in May 2015 . 4. About Eisai Co., Ltd. Eisai's Corporate Concept is "to give first thought to patients and people in the daily living domain, and to increase the benefits that health care provides." Under this Concept (also known as human health care ( hhc ) Concept), we aim to effectively achieve social good in the form of relieving anxiety over health and reducing health disparities. With a global network of R&D facilities, manufacturing sites and marketing subsidiaries, we strive to create and deliver innovative products to target diseases with high unmet medical needs, with a particular focus in our strategic areas of Neurology and Oncology. In addition, we demonstrate our commitment to the elimination of neglected tropical diseases (NTDs), which is a target (3.3) of the United Nations Sustainable Development Goals (SDGs), by working on various activities together with global partners. For more information about Eisai, please visit www.eisai.com (for global headquarters: Eisai. Co., Ltd.), us.eisai.com (for U.S. headquarters: Eisai, Inc.) or www.eisai.eu (for Europe , Middle East , Africa , Russia , Australia and New Zealand headquarters: Eisai Europe Ltd.), and connect with us on X ( global and U.S ), LinkedIn (for global , U.S. and EMEA ) and Facebook ( global ). 5. About Biogen Founded in 1978, Biogen is a leading biotechnology company that pioneers innovative science to deliver new medicines to transform patients' lives and to create value for shareholders and our communities. We apply deep understanding of human biology and leverage different modalities to advance first-in-class treatments or therapies that deliver superior outcomes. Our approach is to take bold risks, balanced with return on investment to deliver long-term growth. The company routinely posts information that may be important to investors on its website at www.biogen.com . Follow Biogen on social media – Facebook , LinkedIn , X , YouTube . Biogen Safe Harbor This news release contains forward-looking statements, about the potential clinical effects of lecanemab; the potential benefits, safety and efficacy of lecanemab; potential regulatory discussions, submissions and approvals and the timing thereof; the treatment of Alzheimer's disease; the anticipated benefits and potential of Biogen's collaboration arrangements with Eisai; the potential of Biogen's commercial business and pipeline programs, including lecanemab; and risks and uncertainties associated with drug development and commercialization. These statements may be identified by words such as "aim," "anticipate," "believe," "could," "estimate," "expect," "forecast," "intend," "may," "plan," "possible," "potential," "will," "would" and other words and terms of similar meaning. Drug development and commercialization involve a high degree of risk, and only a small number of research and development programs result in commercialization of a product. Results in early-stage clinical studies may not be indicative of full results or results from later stage or larger scale clinical studies and do not ensure regulatory approval. You should not place undue reliance on these statements. These statements involve risks and uncertainties that could cause actual results to differ materially from those reflected in such statements, including without limitation unexpected concerns that may arise from additional data, analysis or results obtained during clinical studies; the occurrence of adverse safety events; risks of unexpected costs or delays; the risk of other unexpected hurdles; regulatory submissions may take longer or be more difficult to complete than expected; regulatory authorities may require additional information or further studies, or may fail or refuse to approve or may delay approval of Biogen's drug candidates, including lecanemab; actual timing and content of submissions to and decisions made by the regulatory authorities regarding lecanemab; uncertainty of success in the development and potential commercialization of lecanemab; failure to protect and enforce Biogen's data, intellectual property and other proprietary rights and uncertainties relating to intellectual property claims and challenges; product liability claims; and third party collaboration risks, results of operations and financial condition. The foregoing sets forth many, but not all, of the factors that could cause actual results to differ from Biogen's expectations in any forward-looking statement. Investors should consider this cautionary statement as well as the risk factors identified in Biogen's most recent annual or quarterly report and in other reports Biogen has filed with the U.S. Securities and Exchange Commission. These statements speak only as of the date of this news release. Biogen does not undertake any obligation to publicly update any forward-looking statements. References View original content to download multimedia: https://www.prnewswire.com/news-releases/leqembi-lecanemab-approved-for-the-treatment-of-early-alzheimers-disease-in-mexico-302322515.html SOURCE Eisai Inc.
Thirumavalavan expresses his inability to share stage with VijayConte’s last public act as Spurs head coach after a 3-3 draw at St Mary’s in 2023 was to launch a furious tirade against his own “selfish” players who he claimed “don’t want to play under pressure” before he seemed to turn on the board as he questioned the club’s ongoing trophy drought. Eight days later Conte had left Tottenham by mutual consent after a whirlwind 16-month period, with Postecoglou his eventual permanent successor. A post shared by Antonio Conte (@antonioconte) Postecoglou has been in charge of the Premier League club for two months longer than the Italian, but managed 12 fewer matches and is currently in the middle of an injury crisis which has resulted in a drop in form, with Spurs only able to claim one victory from their last eight fixtures. However, when Postecoglou was asked if he would jump ship in the wake of making remarks like Conte did in March, 2023, he said: “Look, I don’t think it’s fair to comment. “Antonio is a world-class manager and has his own way of doing things, his own reasons for doing that. “I am here, I am in for the fight. I am in a fight, for sure. For better or worse I am not going anywhere at the moment because everything is still in my power and my responsibility. “I still have a real desire to get us through this stage so that people see what is on the other side. My resolve and determination hasn’t wavered one little bit. “I love a fight, I love a scrap, I love being in the middle of a storm when everyone doubts because I know what it is on the other side if you get through it. My job is to get through it.” Postecoglou was Celtic boss when Conte’s extraordinary 10-minute press conference made waves around the world, but acknowledged being aware of his predecessors’ comments and attempted to explain the psyche behind why a manager would make such a move. “I was on Planet Earth at that time, and yes I was well aware of it,” Postecoglou smiled. “I think you know when a manager gets to that point that there’s obviously some underlying issues. “I think most of the time when managers do that they’re trying to get a reaction, trying to get some sort of impact on the team. “In difficult moments, what you want from your leaders is action rather than inaction of just letting things drift along. He did it to try and get a positive impact on the group, one way or another. We’ve all been in that situation as a manager where you feel this is time to send a message.” Postecoglou sent out his own message on Thursday after a 1-1 draw away to Rangers when he insisted Timo Werner’s display “wasn’t acceptable” at Ibrox. Werner was replaced at half-time following an error-strewn performance, but was not alone in being below-par in Glasgow. A day later Postecoglou explained how with Spurs missing several key first-teamers, the onus is on their fit senior players to deliver a level of application and commitment – and admitted Werner will be required at St Mary’s on Sunday. “I’ve got no choice. Who else am I going to play? I’m pulling kids out of school, I literally am,” Postecoglou mentioned in reference to 16-year-old duo Malachi Hardy and Luca Williams-Barnett, who have recently made the bench. “That was the reasoning for me pointing it out last night. We need Timo. We need all of them. “In normal times if you have a poor game, there’s a price to pay. It doesn’t exist right now. We need everybody we’ve got.”NexOptic Technology Corp. ( CVE:NXO – Get Free Report ) shares fell 20% on Friday . The stock traded as low as C$0.02 and last traded at C$0.02. 480,200 shares were traded during trading, an increase of 387% from the average session volume of 98,644 shares. The stock had previously closed at C$0.03. NexOptic Technology Trading Down 20.0 % The stock has a fifty day simple moving average of C$0.03 and a 200 day simple moving average of C$0.02. The company has a debt-to-equity ratio of 56.33, a quick ratio of 0.01 and a current ratio of 0.07. The firm has a market cap of C$3.90 million, a P/E ratio of -1.00 and a beta of 1.14. NexOptic Technology Company Profile ( Get Free Report ) NexOptic Technology Corp., a technology company, develops artificial intelligence and imaging products. It engages in developing All Light Intelligent Imaging Solutions (ALIIS), a suite of intelligent imaging solution that processes raw images and video in real time; and NexCompress technological solutions. Recommended Stories Receive News & Ratings for NexOptic Technology Daily - Enter your email address below to receive a concise daily summary of the latest news and analysts' ratings for NexOptic Technology and related companies with MarketBeat.com's FREE daily email newsletter .