UMaine falls to Fairleigh Dickinson in women’s basketballBiden calls Israel and Hezbollah ceasefire 'good news' as sides come to terms to pause fighting JERUSALEM (AP) — President Joe Biden called Israel and Hezbollah’s ceasefire agreement “good news” and expressed hope that the pause in more than 13 months of fighting will be a catalyst to also end the war in Gaza. Israeli Prime Minister Benjamin Netanyahu said earlier that his security Cabinet had approved a ceasefire deal with Hezbollah, clearing the way for the truce to take effect. Also on Tuesday, Israeli warplanes struck across Lebanon, killing at least 24 people, and the Israeli military issued a flurry of evacuation warnings — a sign it was aiming to inflict punishment on Hezbollah down to the final moments before any ceasefire takes hold. For the first time in the conflict, Israeli ground troops reached parts of Lebanon’s Litani River. AP finds that a Pentagon-funded study on extremism in the military relied on old data Early this year, Pete Hegseth told a Fox News audience a new, Pentagon-funded study proved that the number of military service members and veterans involved in the Jan. 6 insurrection did not indicate a wider problem in the armed forces. Hegseth, Donald Trump's pick to head the Department of Defense, wasn’t alone. The Wall Street Journal’s opinion page highlighted the same report as evidence that extremists in military communities were “phantoms” created by a “false media narrative.” The X account for Republicans on the House Armed Services Committee posted that the study showed the focus on extremism in the military was a “witch hunt.” But The Associated Press has found that the study relied on old data, misleading analyses and ignored evidence that pointed to the opposite conclusion. Trump's threat to impose tariffs could raise prices for consumers, colliding with promise for relief DETROIT (AP) — If Donald Trump makes good on his threat to slap 25% tariffs on everything imported from Mexico and Canada, the price increases that could follow will collide with his campaign promise to give American families a break from inflation. Economists and industry officials say companies would have little choice but to pass along the added costs, dramatically raising prices for food, clothing, automobiles, booze and other goods. The president-elect floated the tariff idea and an additional 10% tax on goods from China, as a way to force the countries to halt the flow of illegal immigrants and drugs into the U.S. But his posts Monday threatening tariffs on his first day in office could be a negotiating ploy to get the countries to change behavior. Mexico suggests it would impose its own tariffs to retaliate against any Trump tariffs MEXICO CITY (AP) — Mexican President Claudia Sheinbaum has suggested Mexico could retaliate with tariffs of its own, after U.S. President-elect Donald Trump threatened to impose 25% tariffs on Mexican goods if the country doesn’t stop the flow of drugs and migrants across the border. Sheinbaum says she is willing to engage in talks on the issues, but said drugs were a U.S. problem. She says "one tariff would be followed by another in response, and so on until we put at risk common businesses,” referring to U.S. automakers that have plants on both sides of the border. After delay, Trump signs agreement with Biden White House to begin formal transition handoff WASHINGTON (AP) — President-elect Donald Trump on Tuesday signed a required agreement with President Joe Biden’s White House to allow his transition team to coordinate with the existing federal workforce ahead of taking office on Jan. 20. The overdue agreement was supposed to have been signed by Oct. 1, according to the Presidential Transition Act, and the Biden White House has issued appeals in both public and private for Trump’s team to sign on. The agreement is a critical step in the process meant to ensure an orderly transfer of power at noon on Jan. 20 and limits the risk that the Trump team could find itself taking control of the massive federal government without being aware of ongoing programs and operations. Brazil’s Bolsonaro participated in a 2022 coup plot, unsealed police report says SAO PAULO (AP) — Brazil’s former far-right President Jair Bolsonaro was fully aware of and actively participated in a coup plot to remain in office after his defeat in the 2022 election, according to a Federal Police report that has been unsealed. Brazil’s Federal Police last Thursday formally accused Bolsonaro and 36 other people of attempting a coup. They sent their nearly 900-page report to the Supreme Court, which lifted the seal. Bolsonaro has repeatedly denied any wrongdoing or awareness of any plot to keep him in power or oust his leftist rival and successor, Luiz Inácio Lula da Silva. Biden proposes Medicare and Medicaid cover costly weight-loss drugs for millions of obese Americans WASHINGTON (AP) — Millions of obese Americans would be eligible to have popular weight-loss drugs like Wegovy or Zepbound covered by Medicare or Medicaid under a new rule the Biden administration proposed Tuesday morning. The proposal, which would not be finalized until after President-elect Donald Trump takes office, could cost taxpayers as much as $35 billion over the next decade. It would give millions of people access to weekly injectables that have helped people shed pounds so quickly that some people have labeled them miracle drugs. New rule allows HIV-positive organ transplants People with HIV who need a kidney or liver transplant will be able to receive an organ from a donor with HIV. That's according to a new rule announced Tuesday by U.S. health officials. Previously, such transplants could be done only as part of research studies. The new rule takes effect Wednesday. It's expected to shorten the wait for organs for all, regardless of HIV status, by increasing the pool of available organs. The practice is supported by a decade of research, during which 500 transplants of kidneys and livers from HIV-positive donors have been done in the U.S. Surveillance tech advances by Biden could aid in Trump's promised crackdown on immigration President-elect Donald Trump will return to power next year with a raft of technological tools at his disposal that would help deliver his campaign promise of cracking down on immigration — among them, surveillance and artificial intelligence technology that the Biden administration already uses to help make crucial decisions in tracking, detaining and ultimately deporting immigrants lacking permanent legal status. One algorithm, for example, ranks immigrants with a “Hurricane Score,” ranging from 1-5, to assess whether someone will “abscond” from the agency’s supervision. Ukraine says Russian attack sets a new record for the number of drones used KYIV, Ukraine (AP) — The Ukrainian air force says Russia launched 188 drones against most regions of Ukraine in a nighttime blitz, describing it as a record number of drones deployed in a single attack. It said Tuesday that most of the drones were intercepted, but apartment buildings and critical infrastructure such as the national power grid were damaged. No casualties were immediately reported in the 17 targeted regions. Russia has been hammering civilian areas of Ukraine with increasingly heavy drone, missile and glide bomb attacks since the middle of the year. The Russian Defense Ministry, meanwhile, issued a rare official acknowledgement of its assets being hit on its own soil by U.S.-made longer-range missiles that the U.S. recently authorized Ukraine to use.NoneInsider Buying: Ero Copper Corp. (TSE:ERO) Director Buys 10,000 Shares of Stock
GOP Bathroom Battle: Cannabis Advocate Nancy Mace Will 'Stand In The Way Of Any Man' Who Tries To Get Into Women's Room
Trajan Group Holdings Limited ( ASX:TRJ – Get Free Report ) insider Rohit Khanna bought 88,235 shares of the business’s stock in a transaction on Monday, December 23rd. The stock was purchased at an average price of A$1.02 ($0.63) per share, for a total transaction of A$89,999.70 ($55,900.43). Trajan Group Stock Performance The company has a quick ratio of 0.42, a current ratio of 0.86 and a debt-to-equity ratio of 54.61. About Trajan Group ( Get Free Report ) Further Reading Receive News & Ratings for Trajan Group Daily - Enter your email address below to receive a concise daily summary of the latest news and analysts' ratings for Trajan Group and related companies with MarketBeat.com's FREE daily email newsletter .
While the Carolina Hurricanes are putting themselves in strong position to eventually secure home-ice advantage in the postseason, the New York Rangers appear to be a shell of the squad that won the teams' second-round playoff series last season in six games. The Hurricanes will attempt to extend their winning home winning streak to nine games, while the Rangers hope to avoid a fourth straight loss when the Metropolitan Division foes convene for the first time this season on Wednesday in Raleigh, N.C. Carolina missed winning the division by three points last season, when it finished with 111. The title instead went to New York, which also won the Presidents' Trophy after racking up a league-best 114 points. Just more than a month into the new season, the Hurricanes own the third-most points in the league (31) and are outscoring foes 41-16 on home ice since taking a 4-1 loss to the Tampa Bay Lightning in their home opener on Oct. 11. Carolina has scored at least four goals in each game of its home winning streak and has hit that mark 16 times overall in 21 games this season. The Hurricanes kept the streak alive with Monday's 6-4 victory over the Dallas Stars. Carolina scored five goals in the third period, including a tiebreaking, power-play goal from Martin Necas with under three minutes left to overcome a 3-1 deficit. "I already know what we have," Carolina coach Rod Brind'Amour said. "It's just, can they grasp how we have to play every shift? I think sometimes we get a little off and try to do things differently, then all of a sudden, we get to the way we have to play... We don't always get the result like that, but you're giving yourself a chance. Really, a game like that, that's what you're hoping you get out of it." Sebastian Aho scored the first goal of the third-period flurry and collected three assists. Seth Jarvis scored in his first game since Nov. 9 and collected two assists, including the secondary helper on the goal by Necas. The Hurricanes are continuing to win despite uncertainty in goal. Frederik Andersen is about a month into his recovery from knee surgery and Pyotr Kochetkov is in the concussion protocol after colliding with defenseman Sean Walker in Saturday's game against the Columbus Blue Jackets. Spencer Martin started in goal Monday. The Rangers raced out to a 5-0-1 start but are just 7-7-0 since then and have lost three straight. New York ended its four-game road trip with a 6-2 loss to the Edmonton Oilers on Saturday and produced another dud in a 5-2 home loss to the St. Louis Blues Monday. Will Cuylle scored twice, but big names Vincent Trocheck, Artemi Panarin and Mika Zibanejad combined for six shots on goal and were a combined minus-7 as the Rangers were outshot 44-29. "We need to be better," New York coach Peter Laviolette said. "Everybody needs to be better. It's not good enough what we're doing." Monday's loss came after reports surfaced that general manager Chris Drury told other teams he may be willing to trade forward Chris Kreider and defenseman Jacob Trouba, who has a no-move clause to 15 teams. Kreider on Monday missed his first game since Jan. 16, 2023, due to an upper-body injury and is day-to-day. He has nine goals in 19 games this season. Trouba was on the ice for two goals Monday and has just two points since collecting four assists in the first three games this season. This article first appeared on Field Level Media and was syndicated with permission.
New gene drive reverses insecticide resistance in pests... then disappears November 22, 2024 University of California - San Diego Geneticists have developed a gene drive-based solution to the widespread problem of insecticide resistance. In an effort to protect valuable crops, the researchers created an 'e-Drive' that reverses insecticide resistance and then disappears from the insect population. Facebook Twitter Pinterest LinkedIN Email Insecticides have been used for centuries to counteract widespread pest damage to valuable food crops. Eventually, over time, beetles, moths, flies and other insects develop genetic mutations that render the insecticide chemicals ineffective. Escalating resistance by these mutants forces farmers and vector control specialists to ramp up use of poisonous compounds at increasing frequencies and concentrations, posing risks to human health and damage to the environment since most insecticides kill both ecologically important insects as well as pests. To help counter these problems, researchers recently developed powerful technologies that genetically remove insecticide-resistant variant genes and replace them with genes that are susceptible to pesticides. These gene-drive technologies, based on CRISPR gene editing, have the potential to protect valuable crops and vastly reduce the amount of chemical pesticides required to eliminate pests. Still, gene-drive systems have come under scrutiny with concerns that once they are released into a population they could continuously spread unchecked. University of California San Diego geneticists have now developed a solution to this concern. Publishing in the journal Nature Communications , School of Biological Sciences Postdoctoral Scholar Ankush Auradkar and Professor Ethan Bier led the creation of a new genetic system that converts insecticide-resistant forms of mutated insect genes back to their natural, native form. The novel system is designed to spread the original "wild type" version of the gene using the biased inheritance of specific genetic variants known as alleles and then disappear, leaving only a population of insects with the corrected version of the gene. "We have developed an efficient biological approach to reverse insecticide resistance without creating any other perturbation to the environment," said Bier, a professor in the Department of Cell and Developmental Biology, of the self-eliminating allelic drive, or "e-Drive." "The e-Drive is programmed to act transiently and then disappear from the population." As described in the paper, the researchers created a novel genetic "cassette," a small group of DNA elements, and inserted it inside fruit flies as a proof-of-concept technology that could be applied to other insects. They developed the e-Drive to target a gene known as the voltage gated sodium ion channe l, or vgsc , which is required for proper nervous system functioning. The e-Drive cassette is designed to spread through CRISPR gene editing and features a guide RNA that binds to a Cas9 DNA protein and makes a cut at the targeted vgsc insecticide resistant gene site. The gene is then switched out for a native copy of the gene that is susceptible to insecticides. Per the study, when insects carrying the cassette are introduced into a target population, they mate randomly and transmit the e-Drive cassette to their offspring. To maintain control of the e-Drive's spread, the researchers imposed a fitness check on those carrying the cassette, either through limited viability or fertility. The cassette was inserted on the X-chromosome and reduced the mating success of males, resulting in reduced offspring. The frequency of the cassette in the population eventually declines through each generation until it fully vanishes from the population. In laboratory experiments all of the offspring were converted to native genes in eight-to-10 generations, which took about six months in flies. "Because insects carrying the gene cassette are penalized with a severe fitness cost, the element is rapidly eliminated from the population, lasting only as long as it takes to convert 100 percent of the insecticide-resistant forms of the target gene back to wild-type," said Auradkar. The researchers note that the self-eliminating nature of the e-Drive means it can be introduced and re-introduced as needed, and as different types of pesticides are used. The researchers are now developing a similar e-Drive system in mosquitoes to help prevent the spread of malaria. In addition to Auradkar and Bier, the coauthors of the Nature Communications paper included their close collaborators Rodrigo Corder of the Institute of Biomedical Science, University of SãoPaulo; and John Marshall of the Innovative Genomics Institute, who performed sophisticated mathematical modeling that revealed important hidden features of the e-Drive system, including its ability to efficiently cull a class of individuals in which the drive process did not occur. Story Source: Materials provided by University of California - San Diego . Original written by Mario Aguilera. Note: Content may be edited for style and length. Journal Reference : Cite This Page :The officials at the 2024 Maui Invitational likely aren't going to get many holiday cards from UConn head coach Dan Hurley. Hurley was issued a critical technical foul in the final minute of Monday's overtime loss to Memphis when he protested an over-the-back call against Liam McNeeley. That was surely on his mind Tuesday when officials did not call a potential over-the-back foul on Colorado as it grabbed an offensive rebound to keep a possession alive in the final 30 seconds. UConn assistant coaches had to hold Hurley back from protesting too much after Tuesday's no-call, and the coach was surely even more upset when that possession ended with Colorado scoring what proved to be the winning basket in a 73-72 victory. Hurley called Tuesday's no-call "more egregious" and "ironic," although he blamed his team's "dreadful" defense for the loss: That he blamed the defense and not the officials for the end result was a change from Monday's outcome. After all, he was asked if he believed his technical foul and the ensuing two free throws cost his team the game against Memphis since the Tigers won by two points and told reporters , "I think it was the s--tty calls. I would expect to come to play in an event, and I don't know too many back-to-back national championship teams that get that type of a whistle." He didn't stop there and continued to criticize the officials in the aftermath of Monday's loss: Yet Tuesday's game felt different. While an over-the-back call would have been a key development at that time considering there were fewer than 30 seconds remaining and the Huskies had a one-point lead, that one no-call didn't determine the outcome of the entire game. Rather, UConn blew a double-digit lead against a team it was expected to defeat. Had it not taken its proverbial foot off the pedal and allowed the Buffaloes back into the game, the no-call wouldn't have taken on as much importance. The Huskies also still had the lead when Colorado came down with the controversial offensive rebound. They still had the opportunity to get a defensive stop to clinch the win but instead allowed Andrej Jakimovski to drive the lane and score the winning basket. Hurley's team also could have scored in the final seconds after Jakimovski's basket, but Hassan Diarra's three-pointer didn't fall. The head coach himself recognized the defense that allowed Colorado to shoot 51.1 percent from the field and 56.3 percent from deep was a bigger problem than the officials in the outcome of the game. Fortunately for the Huskies, they still have plenty of time to turn things around this season even with back-to-back losses in the early going.
Rams don't dominate, but they're rolling toward the playoffs with superb complementary football
CANCUN, Mexico (AP) — Darryl Simmons II scored 19 points to help Gardner-Webb defeat SE Louisiana 73-69 on Tuesday. Simmons shot 7 for 13 (2 for 5 from 3-point range) and 3 of 3 from the free-throw line for the Runnin' Bulldogs (3-3). Pharell Boyogueno scored 15 points while going 6 of 13 (3 for 7 from 3-point range) and added seven rebounds and four steals. Anthony Selden shot 6 of 10 from the field and 3 of 6 from the free-throw line to finish with 15 points. Jeremy Elyzee led the Lions (2-4) in scoring, finishing with 22 points, three steals and two blocks. Sam Hines Jr. added 12 points, seven rebounds, six assists and four steals. Jakevion Buckley finished with 11 points, four assists and three steals. The Associated Press created this story using technology provided by Data Skrive and data from Sportradar .
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