MELBOURNE, Australia, Nov. 21, 2024 (GLOBE NEWSWIRE) -- Immuron Limited (ASX: IMC; NASDAQ: IMRN) is pleased to advise our Chief Executive Officer, Steven Lydeamore presented early this morning at the 21st Virtual Investor Summit Microcap Event (November 21, US Eastern Time). A copy of the presentation is available on the Company’s website. https://www.immuron.com.au/corporate-presentations/ This release has been authorised by the directors of Immuron Limited. COMPANY CONTACT: Steven Lydeamore Chief Executive Officer steve@immuron.com About Immuron Immuron Limited (ASX: IMC, NASDAQ: IMRN), is an Australian biopharmaceutical company focused on developing and commercializing orally delivered targeted polyclonal antibodies for the treatment of infectious diseases. About Travelan® Travelan® is an orally administered passive immunotherapy that prophylactically reduces the likelihood of contracting travelers’ diarrhea, a digestive tract disorder that is commonly caused by pathogenic bacteria and the toxins they produce. Travelan® is a highly purified tabletized preparation of hyper immune bovine antibodies and other factors, which when taken with meals bind to diarrhea-causing bacteria and prevent colonization and the pathology associated with travelers’ diarrhea. In Australia, Travelan® is a listed medicine on the Australian Register for Therapeutic Goods (AUST L 106709) and is indicated to reduce the risk of Travelers’ Diarrhea, reduce the risk of minor gastro-intestinal disorders and is antimicrobial. In Canada, Travelan® is a licensed natural health product (NPN 80046016) and is indicated to reduce the risk of Travelers’ Diarrhea. In the U.S., Travelan® is sold as a dietary supplement for digestive tract protection. Travelers’ diarrhea (TD) TD is generally defined as the passage of ≥ 3 unformed stools per 24 hours plus at least one additional symptom (such as nausea, vomiting, abdominal cramps, fever, blood/mucus in the stools, or fecal urgency) that develop while abroad or within 10 days of returning from any resource-limited destinations ( Leung et al., 2006 ). Diarrhea continues to be the most frequent health problem among travelers to destinations in lower- and middle-income regions ( Steffen, 2017 ). Deployed US military personnel, essentially representing a long-term traveller population, are particularly affected given their population dynamics and the context in which they seek care and treatment ( Connor et al., 2012 ). Diarrhea is the leading infectious disease threat to the overall health and preparedness of deployed US armed forces, with diarrheagenic E. coli, Campylobacter spp., and Shigella spp. among the most commonly reported etiologies ( Riddle et al., 2006 ). Immuron Platform Technology Immuron’s proprietary technology is based on polyclonal immunoglobulins (IgG) derived from engineered hyper-immune bovine colostrum. Immuron has the capability of producing highly specific immunoglobulins to any enteric pathogen and our products are orally active. Bovine IgG can withstand the acidic environment of the stomach and is resistant to proteolysis by the digestive enzymes found in the Gastrointestinal (GI) tract. Bovine IgG also possesses this unique ability to remain active in the human GI tract delivering its full benefits directly to the bacteria found there. The underlying nature of Immuron’s platform technology enables the development of medicines across a large range of infectious diseases. The platform can be used to block viruses or bacteria at mucosal surfaces such as the Gastrointestinal tract and neutralize the toxins they produce. IMM-124E (Travelan®) IMM-124E was developed using Immuron’s platform technology. IMM-124E is produced from the colostrum of birthing cattle that have been immunised during pregnancy with a vaccine containing the outer antigens of multiple human derived ETEC. A total of 13 ETEC strains are used in the vaccine to produce high levels of antibodies against selected surface antigens from the most common strains of ETEC. The resultant hyperimmune colostrum IMM-124E from ETEC vaccinated cows contains significant levels of polyclonal antibodies specific for ETEC antigens LPS, CFA-I and Flagellin ( Sears et al., 2017 ). The antibodies produced in IMM-124E have been found to have a stronger binding and neutralizing activity (than the antibodies of unvaccinated cattle) against a wide range of LPS antigens including both the variable O-polysaccharide region and the preserved oligosaccharide core ‘R’ region of LPS from the 13 serotypes used in the ETEC vaccine. IMM-124E is manufactured into a tablet form referred to as Travelan®. IMM-529 Immuron is developing IMM-529 as an adjunctive therapy in combination with standard of care antibiotics for the prevention and/or treatment of recurrent Clostridioides difficile infection (CDI). IMM-529 antibodies targeting Clostridioides difficile (C. diff) may help to clear CDI infection and promote a quicker re-establishment of normal gut flora, providing an attractive oral preventative for recurrent CDI. Immuron is collaborating with Dr. Dena Lyras and her team at Monash University, Australia to develop vaccines to produce bovine colostrum-derived antibodies. Dairy cows were immunised to generate hyperimmune bovine colostrum (HBC) that contains antibodies targeting three essential C. diff virulence components. IMM-529 targets Toxin B (TcB), the spores and the surface layer proteins of the vegetative cells. This unique 3-target approach has yielded promising results in pre-clinical infection and relapse models, including (1) Prevention of primary disease (80% P =0.0052); (2) Protection of disease recurrence (67%, P BEREA, Ohio (AP) — Myles Garrett didn't know he had joined a prestigious list of defensive stars last week until one of his biggest fans pointed it out to him. “My dad was hyped about it,” he said. For good reason. With three sacks last week in Cleveland's 24-19 win in prime time over the Pittsburgh Steelers, Garrett became the seventh player to reach double-digit sacks in seven straight seasons since the stat became official in 1982. The others: Lawrence Taylor (1984-90), Reggie White (1985-93), Bruce Smith (1992-98), John Randle (1992-99), DeMarcus Ware (2006-12) and Jared Allen (2007-13). All of them is in the Hall of Fame except for Allen. “Hall of Famer,” Garrett said in praising the retired Minnesota Vikings edge rusher, who is again on the doorstep of induction as a semifinalist for the fifth straight year. Garrett is on track to get his own bronze bust one day in Canton, but until then, he's humbled to be in such elite company. “Guys I looked up to when I started my journey into this game,” said Garrett, who tries to bolster his resume on Monday night when the Browns (3-8) visit the Denver Broncos (7-5). “It’s absolutely amazing to be amongst those guys, not just looking up at them but looking side to side and standing amongst them. "So I want to continue to find myself on those lists and hopefully stand alone at the end of the day.” He's on his way. The NFL's reigning Defensive Player of the Year is having another monster season but probably not getting the recognition he deserves as the Browns, upended by continuous quarterback issues, have fallen way short of expectations. Garrett used the national TV platform against the Steelers to remind any detractors of his greatness. He sacked Russell Wilson three times, forced a fumble and outplayed Pittsburgh's T.J. Watt, the player to whom he is most often compared. The Garrett vs. Watt debate went to another level in February. On the day Garrett received his DPOY award, second-place finisher Watt seemed to take a shot at the Browns star by posting “Nothing I'm not used to” on social media. Those comments stuck with Garrett, who following the win over Pittsburgh — and Watt being held without a sack — didn't hold back in declaring himself the league's best pass rusher. “I wanted to make it known that I’m the guy, I’m the No. 1 edge defender,” Garrett said. It was an unusual boast from Garrett, who was asked why he felt he needed to express himself. “Because part of my journey of being the best player that I can be is I think I can be the best player that there is currently,” he said. ”So I have to live up to those expectations I have for myself. That’s just on the road to be the player that I want to be.” Garrett's unrelenting drive is what sets him apart. Although he'll enter Monday's game with 98 1/2 sacks and can become just the fifth player to reach 100 in his first eight seasons, joining White, Ware, Allen and Watt, it's not enough. “I still took too long,” said Garrett, who can become the first to do it before turning 29. “It’d have been tough to catch Mr. White, but hopefully this next however many number will come quicker than the first 100. So we’ll go out there and we’ll do what I do and try to take it up a notch.” Browns defensive coordinator Jim Schwartz marvels at Garrett's output despite double- and triple-team blocking. “He just continues to do stuff,” Schwartz said. “His production is so high, even though he’s a marked man, even though every game plan starts with, ‘Don’t let 95 wreck the game,’ and he still finds a way to wreck games.” Schwartz doesn't need to see any lists to know Garrett belongs among the best to ever rush a quarterback. “Yes, he does,” Schwartz said. "I think he’s just starting to hit his prime. I think he still has a lot left in front of him. The sky is the limit as far as he goes. And when it’s all said and done, maybe you’re comparing other people to him. That should probably be a goal for him.” AP NFL: https://apnews.com/hub/nflWall Street's Mixed Signals: Nasdaq's Milestone & Economic UncertaintiesET CEO Roundtable: 'Animal spirits need a release,' says BCCL CEO Sivakumar Sundaram
NFL world reacts with excitement, surprise, questions after Bill Belichick is hired to coach UNCThe Nigerian Content Development and Monitoring Board (NCDMB), on Thursday, said it has executed the engineering, procurement, and construction contract with Julius Berger PLC for the development of Oloibiri Museum and Research Centre (OMRC), to be located at Otuabagi, Ogbia Local Government Area of Bayelsa State. The Executive Secretary, NCDMB, Engr. Felix Omatsola Ogbe, according to the statement, executed the contract at the Board’s liaison office in Abuja, with the project construction to be delivered within 30 months. It stated that the Oloibiri Museum and Research Centre (OMRC) is being financed by the Petroleum Development Technology Fund (PTDF), NCDMB, Shell Petroleum Development Company/Nigerian National Petroleum Company Ltd and the Bayelsa State Government, in the ratio of 40:30:20 and 10 respectively. It added that the project is registered by guarantee, with the four organisations serving as partners. The contract agreement has been approved by the partners and signed by Julius Berger PLC. The statement noted that the Executive Secretary of NCDMB serves as the chairman of the registered company, hence he signed the contract on behalf of the partners, with the Director Legal Services, NCDMB, Mr. Naboth Onyesoh, Esq serving as the Secretary of the company. Part of the statement read: “The President Muhammadu Buhari administration had in February 2023 awarded the contract for the Engineering, Procurement and Construction scope of the OMRC to Julius Berger at the sum of N117billion. “The groundbreaking of the OMRC was performed in February 2023, a colorful ceremony attended by leading government officials, oil and gas stakeholders and community members.” Ogbe expressed delight on the execution of the contract, which marked the commencement of construction activities. He noted that the project will catalyze immense economic benefits for the Bayelsa and the national economy during the construction and operation stages. He thanked the partners of the project and other stakeholders who contributed to the success of the project to date. He indicated that the project was conceived to pay homage to the birthplace of Nigeria’s hydrocarbon commercial production journey which commenced in 1958. He added that President Bola Tinubu believes that the project is long overdue hence the multi- level government and private sector collaboration was engineered to actualize the establishment of the project. “The OMRC project is expected to deliver a world-class oil and gas museum, showcasing the history of crude oil production in Nigeria and display of geological formations, early equipment, tools, and platforms used in the evolution of oil and gas activities. “In addition, the research testing center that will provide a facility where field trials of prototypes of oil and gas related indigenous research will be conducted, grant access to university students in oil and gas related disciplines to potentially better understand indigenous oil and gastechnology advancements. “The OMRC project will also facilitate the commercialization of research through the creation of a suitable ecosystem for the development of home-grown technology for oil and gas operations and create a new commercial value chain from Museum and Research operations that will generate employment for Nigerians.”FCS championship game headed to Nashville for 2025, 2026 seasons
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Daily Post Nigeria 16 Days of Activism: Ogun commits to safety for women, girls Home News Politics Metro Entertainment Sport News 16 Days of Activism: Ogun commits to safety for women, girls Published on December 4, 2024 By Timi Owolabi To reduce the menace of Gender-Based Violence, GBV, the Ogun State Commissioner for Women Affairs and Social Development, Adijat Adeleye, has called for action to raise voices for and make commitments to the safety of women and girls. Adeleye made this call at a town hall meeting in partnership with the United Nations Population Fund, UNFPA, community and other opinion leaders on prevention and response to GBV held in Abeokuta on Wednesday. She said the meeting was in commemoration of the 16 Days Activism on the elimination of all forms of violence against the female gender, stating that community leaders comprising Baales, religious leaders, and Community Development Association leaders, among others, were gatekeepers of the community. The commissioner emphasised that they exhibit a significant role in shaping minds, influencing behaviours and building trust, charging them to look beyond ongoing campaigns to make a lasting impact in the fight against GBV in their respective communities. “We need to implement these plans; action they say is key. This is not a checklist we can tick and move on. It’s a breathing process and it starts with you. You have to walk the talk. So, when we create action plans, ensure they don’t collect dust on some shelf. Make sure they are enforced; talk about it in your communities, churches, mosques, garages and parks, and share from one leader to another,” she said. While reeling out the strides of the Abiodun-led administration in ridding the state of GBV, the commissioner stated that the government had established Sexual Assault Referral Centres, SARC, in zones of the state in collaboration with the United Nations Population Fund, UNFPA, and Ogun State Transformation Projects, OGSTEP. The centres, she added, were equipped to provide immediate care, support and counselling for survivors of GBV. She added that this intervention aimed to facilitate the commencement of the healing process for survivors, revealing that toll-free lines had equally been provided for a quick response from the government-trained responders and service providers. In her welcome address, the Permanent Secretary in the ministry, Adejumoke Adewole, underscored the importance of a collective mission to raise awareness of GBV and advocate for the rights and dignity of women and girls in communities. She implored the stakeholders to use their positions to speak on behalf of the voiceless, particularly women and girls, calling on them to work together with the state government and UNFPA to curb structures perpetuating violence in society. Earlier in her lecture titled “Roles of Community Leaders in Responding and Preventing GBV,” UNFPA’s gender analyst, Dr Esther Somefun, highlighted some of the key roles of community leaders as embracing and encouraging survivors of GBV, avoiding discrimination towards them, reporting acts of violence against women and girls at all times and publicising the toll-free lines for reporting GBV. While delivering another lecture, a representative of APIN Public Health Initiatives, Favour Ojo-Omoniyi, noted that opinion leaders needed to equip themselves with necessary education about GBV and prepare to offer support to survivors. Representative of the Forum of Muslim Women Association of Nigeria, FOMWAN, Zainab Jinadu and her counterpart from the National Union of Road Transport Workers, NURTW, Osioyemi Olasunkanmi, commended the state government and UNFPA for coming up with the idea of involving them as gatekeepers of the community in eliminating GBV cases. Related Topics: 16 Days of Activism ogun Don't Miss Tax reforms crucial for national growth — NOA You may like Abiodun presents N1.055tn 2025 budget to Ogun Assembly Ogun pledges to break down societal stereotypes, provide job opportunities for PWDs Police confirm suspected assassination of hotel guest in Ogun Teacher attempts suicide as Ogun pupil loses eye to classroom accident Man slumps, dies while walking on Ogun road Why I consistently focus on development of Ogun West – Gov. Abiodun Advertise About Us Contact Us Privacy-Policy Terms Copyright © Daily Post Media Ltd
Jones, Mellott help Montana State run over Montana 34-11
NEW YORK (AP) — No ex-president had a more prolific and diverse publishing career than Jimmy Carter . His more than two dozen books included nonfiction, poetry, fiction, religious meditations and a children’s story. His memoir “An Hour Before Daylight” was a Pulitzer Prize finalist in 2002, while his 2006 best-seller “Palestine: Peace Not Apartheid” stirred a fierce debate by likening Israel’s policies in the West Bank to the brutal South African system of racial segregation. And just before his 100th birthday, the Dayton Literary Peace Prize Foundation honored him with a lifetime achievement award for how he wielded “the power of the written word to foster peace, social justice, and global understanding.” In one recent work, “A Full Life,” Carter observed that he “enjoyed writing” and that his books “provided a much-needed source of income.” But some projects were easier than others. “Everything to Gain,” a 1987 collaboration with his wife, Rosalynn, turned into the “worst threat we ever experienced in our marriage,” an intractable standoff for the facilitator of the Camp David accords and winner of the Nobel Peace Prize. According to Carter, Rosalynn was a meticulous author who considered “the resulting sentences as though they have come down from Mount Sinai, carved into stone.” Their memories differed on various events and they fell into “constant arguments.” They were ready to abandon the book and return the advance, until their editor persuaded them to simply divide any disputed passages between them. “In the book, each of these paragraphs is identified by a ‘J’ or an ‘R,’ and our marriage survived,” he wrote. Here is a partial list of books by Carter: “Keeping Faith: Memoirs of a President” “The Blood of Abraham: Insights into the Middle East” (With Rosalynn Carter) “Everything to Gain: Making the Most of the Rest of Your Life” “An Outdoor Journal: Adventures and Reflections” “Turning Point: A Candidate, a State, and a Nation Come of Age” “Always a Reckoning, and Other Poems” (With daughter Amy Carter) “The Little Baby Snoogle-Fleejer” “Living Faith” “The Virtues of Aging” “An Hour Before Daylight: Memories of a Rural Boyhood” “Christmas in Plains: Memories” “The Hornet’s Nest: A Novel of the Revolutionary War” “Our Endangered Values: America’s Moral Crisis” “Faith & Freedom: The Christian Challenge for the World” “Palestine: Peace Not Apartheid” “A Remarkable Mother” “Beyond the White House” “We Can Have Peace in the Holy Land: A Plan That Will Work” “White House Diary” “NIV Lessons from Life Bible: Personal Reflections with Jimmy Carter” “A Call to Action: Women, Religion, Violence, and Power” “A Full Life: Reflections at Ninety”