Swiped: The School That Banned Smartphones review – makes you long to lock your own device in a box
FRISCO, Texas (AP) — A rare win as a double-digit underdog came just in time to let the Dallas Cowboys believe their playoff hopes aren't completely gone in 2024. Cooper Rush probably will need three more victories in a row filling in for the injured Dak Prescott for any postseason talk to be realistic. The thing is, the Cowboys (4-7) could be favored in two of those games, and already are by four points as an annual Thanksgiving Day host against the New York Giants (2-9) on Thursday, according to BetMGM. Not to mention the losing record at the moment for each of the next four opponents for the defending NFC East champions, playoff qualifiers each of the past three seasons. The Cowboys have a chance to make something of the improbable and chaotic 34-26 win at Washington that ended a five-game losing streak. “Behind the eight ball,” Micah Parsons said, the star pass rusher acknowledging the reality that Dallas hadn't done much yet. “Let’s see how we can handle adversity and see if we can make a playoff run. But we got a long way to go.” It was a start, though, powered in part by the best 55 minutes from the Dallas defense since the opener, when the Cowboys dismantled Cleveland and looked the part of a Super Bowl contender. The last five minutes for the Dallas defense against the Commanders looked a lot like most of the nine games after that 33-17 victory over the Browns. Which is to say not very good. Jayden Daniels easily drove Washington 69 yards to a touchdown before throwing an 86-yard scoring pass in the final seconds to Terry McLaurin, who weaved through five defenders when a tackle might have ended the game. The Cowboys kept a 27-26 lead thanks to Austin Seibert's second missed extra point, and withstood another blunder when Juanyeh Thomas returned an onside kick recovery for a TD rather than slide and leave one kneel-down from Rush to end the game. Dallas will have to remember it did hold a dynamic rookie quarterback's offense to 251 yards before the madness of the ending in the Cowboys' biggest upset victory since 2010 at the New York Giants. That one was too late to save the season. This one might not be. “We needed it,” embattled coach Mike McCarthy said. “It’s been frustrating, no doubt. We’ve acknowledged that. We’ve got another one right around the corner here, so we have to get some wins and get some momentum.” What's working Rush ended a personal three-game losing streak with his best showing since the previous time he won as the replacement for Prescott, who is out for the season after surgery for a torn hamstring. The 117.6 passer rating was Rush's best as a starter, and the NFL's second-worst rushing attack played a solid complementary role with Rico Dowdle gaining 86 yards on 19 carries. What needs help KaVontae Turpin's electrifying 99-yard kickoff return did more than lift the Cowboys when it appeared an 11-point lead might get away in the final five minutes. It eased the worst day of special teams for Dallas since John Fassel took over that phase four years ago. Suddenly struggling kicker Brandon Aubrey had one field-goal attempt blocked and missed another. Bryan Anger had a punt blocked. For the second time in five games, Aubrey's attempt to bounce a kickoff in front of the return man backfired. The ball bounced outside the landing zone, putting the Commanders at the 40-yard line to start the second half and setting up the drive to the game's first touchdown. Stock up CB Josh Butler, whose NFL debut earlier this season came five years after the end of his college career, had 12 tackles, a sack and three pass breakups. The pass breakups were the most by an undrafted Dallas player since 1994. Stock down Rookie LT Tyler Guyton, who has had an up-and-down season with injuries and performance issues, was benched immediately after getting called for a false start in the fourth quarter. His replacement, Asim Richards, could be sidelined with a high ankle sprain that executive vice president of personnel Stephen Jones revealed on his radio show Monday. Veteran Chuma Edoga, who was the projected starter at Guyton's position before a preseason toe injury, was active but didn't play against the Commanders. He's awaiting his season debut. Injuries The status of perennial All-Pro RG Zack Martin (ankle/shoulder) and LG Tyler Smith (ankle/knee) will be a question on the short week after both sat against Washington. Stephen Jones indicated Smith could be available and said the same of WR Brandin Cooks, who hasn't played since Week 4 because of a knee issue. TE Jake Ferguson may miss at least a second week with a concussion. The short week might make it tough for CB Trevon Diggs (groin/knee) to return. Key number 75% — Rush's completion rate, his best with at least 10 passes. He was 24 of 32 for 247 yards with two touchdowns and no interceptions. His other game with multiple TDs and no picks was a 25-10 victory over Washington two years ago, when he went 4-1 with Prescott sidelined by a broken thumb. Next steps There's some extra rest after the short week, with Cincinnati making a “Monday Night Football” visit on Dec. 9. The next road game is at Carolina on Dec. 15. AP NFL: https://apnews.com/hub/nflSocial Security tackles overpayment ‘injustices,’ but problems remainNoneCanada shares higher at close of trade; S&P/TSX Composite up 0.33%
China Sanctions 7 Firms Over US Military Support For TaiwanTrump selects longtime adviser Keith Kellogg as special envoy for Ukraine and RussiaJUSTIN HERBERT THREW three touchdowns as the Los Angeles Chargers booked their place in the NFL playoffs with a blowout 40-7 win at the New England Patriots on Saturday. The Patriots, who suffered a sixth straight loss, were booed off the field by the remaining fans at Gillette Stadium as they fell to 3-13 on the season. But for the Chargers it was a job well done as the confident Herbert ensured a second post-season place in three seasons with another accomplished quarterback display. Herbert completed 28 of 38 passes and threw for 281 yards against a Patriots defense that caused few issues against the passing game. The Chargers took the lead late in the first quarter thanks to a beautiful 23-yard Herbert pass, superbly caught by the diving Derius Davis. After a Cameron Dicker field goal early in the second, Herbert found rookie receiver Ladd McConkey at the back of the end-zone with a pinpoint pass to make it 17-0. Patriots rookie quarterback Drake Maye had been forced out of the game in the first quarter after suffering a hit to the head by Cam Hart when running down the sideline. But Maye, who had been cleared to return for the second quarter, showed he was in good shape with a fine 36-yard touchdown pass to DeMario Douglas to give the Patriots some hope. But the Chargers ran away with the game with Herbert again connecting with McConkey, this time with a 40-yard pass down the middle and a two-yard rush from J.K Dobbins in the fourth completed the rout. Herbert’s performance meant he set a new record for the most passing yards in the first five years of an NFL career — passing Peyton Manning’s tally of 20,618 yards. But the quarterback, who has yet to win a playoff game, was quick to give credit for his achievement to his team-mates. “It says so much about the guys we had catching those passes and a great offensive line giving me the time to get the ball off and (the defense) getting me the ball back,” he said. “I couldn’t have done it without them,” he added. The Denver Broncos can clinch a place in the playoffs when they face the Bengals in Cincinnati later on Saturday.The United States saw an 18.1% increase in homelessness this year, a dramatic rise driven mostly by a lack of affordable housing as well as devastating natural disasters and a surge of migrants in several parts of the country, federal officials said Friday. The U.S. Department of Housing and Urban Development said federally required tallies taken across the country in January found more than 770,000 people were counted as homeless — a number that misses some people and does not include those staying with friends or family because they don't have a place of their own. That increase comes on top of a 12% increase in 2023, which HUD blamed on soaring rents and the end of COVID-19 pandemic assistance. The 2023 increase also was driven by people experiencing homelessness for the first time. The numbers overall represent 23 of every 10,000 people in the U.S., with Black people being overrepresented among the homeless population. People are also reading... A man walks past a homeless encampment Oct. 25, 2023, in downtown Los Angeles. Jae C. Hong, Associated Press "No American should face homelessness, and the Biden-Harris Administration is committed to ensuring every family has access to the affordable, safe, and quality housing they deserve," HUD Agency Head Adrianne Todman said in a statement, adding that the focus should remain on "evidence-based efforts to prevent and end homelessness." Among the most concerning trends was a nearly 40% rise in family homelessness — one of the areas that was most affected by the arrival of migrants in big cities. Family homelessness more than doubled in 13 communities impacted by migrants including Denver, Chicago and New York City, according to HUD, while it rose less than 8% in the remaining 373 communities. Almost 150,000 children experienced homelessness on a single night in 2024, reflecting a 33% jump from last year. Disasters also played a part in the rise in the count, especially last year's catastrophic Maui wildfire, the deadliest U.S. wildfire in more than a century. More than 5,200 people were in emergency shelters in Hawaii on the night of the count. Louisiana Wildlife and Fisheries agents assist state police as they order people living in a homeless encampment to move to a different designated location during a sweep ahead of a Taylor Swift concert in New Orleans. Gerald Herbert, Associated Press "Increased homelessness is the tragic, yet predictable, consequence of underinvesting in the resources and protections that help people find and maintain safe, affordable housing," Renee Willis, incoming interim CEO of the National Low Income Housing Coalition, said in a statement. "As advocates, researchers, and people with lived experience have warned, the number of people experiencing homelessness continues to increase as more people struggle to afford sky-high housing costs." Robert Marbut Jr., the former executive director of the U.S. Interagency Council on Homelessness from 2019 to 2021, called the nearly 33% increase in homelessness over the past four years "disgraceful" and said the federal government needs to abandon efforts to prioritize permanent housing. "We need to focus on treatment of substance use and mental illness, and bring back program requirements, like job training," Marbut said in an email. Listen now and subscribe: Apple Podcasts | Spotify | RSS Feed | SoundStack | All Of Our Podcasts The numbers also come as increasing numbers of communities are taking a hard line against homelessness. People living in a homeless encampment pick up belongings Oct. 23 after Louisiana State Police ordered them to move to a different designated location during a sweep ahead of a Taylor Swift concert in New Orleans. Gerald Herbert, Associated Press Angered by often dangerous and dirty tent camps, communities — especially in Western states — have enforced bans on camping. That follows a 6-3 ruling this summer by the Supreme Court that found outdoor sleeping bans don’t violate the Eighth Amendment. Homeless advocates argued that punishing people who need a place to sleep would criminalize homelessness. There was some positive news in the count, as homelessness among veterans continued to trend downward. Homelessness among veterans dropped 8% to 32,882 in 2024. It was an even larger decrease for unsheltered veterans, declining 11% to 13,851 in 2024. "The reduction in veteran homelessness offers us a clear roadmap for addressing homelessness on a larger scale," Ann Oliva, CEO of the National Alliance to End Homelessness, said in a statement. "With bipartisan support, adequate funding, and smart policy solutions, we can replicate this success and reduce homelessness nationwide. Federal investments are critical in tackling the country's housing affordability crisis and ensuring that every American has access to safe, stable housing." Several large cities had success bringing down their homeless numbers. Dallas, which worked to overhaul its homeless system, saw a 16% drop in its numbers between 2022 to 2024. Los Angeles, which increased housing for the homeless, saw a drop of 5% in unsheltered homelessness since 2023. A rat sniffs the hand of a sleeping man experiencing homelessness Dec. 18 in downtown Los Angeles. Damian Dovarganes, Associated Press California, the most populous state in the U.S., continued to have the nation's largest homeless population, followed by New York, Washington, Florida and Massachusetts. The sharp increase in the homeless population over the past two years contrasts with success the U.S. had for more than a decade. Going back to the first 2007 survey, the U.S. made steady progress for about a decade in reducing the homeless population as the government focused particularly on increasing investments to get veterans into housing. The number of homeless people dropped from about 637,000 in 2010 to about 554,000 in 2017. The numbers ticked up to about 580,000 in the 2020 count and held relatively steady over the next two years as Congress responded to the COVID-19 pandemic with emergency rental assistance, stimulus payments, aid to states and local governments and a temporary eviction moratorium. Emergency housing resources for older Americans in need Emergency housing resources for older Americans in need Homelessness is intertwined with the cost of living, and the high cost of living is hitting older adults fairly hard. A Westat survey for the Department of Health and Human Services found that older adults are the fastest-growing cohort of the homeless population. Emergency housing for seniors can keep that number from climbing higher. Caring.com details how to access it. The number of homeless seniors isn't based solely on people remaining homeless as they age; it also includes those whose first experience with homelessness came after they turned 50. In 2023, The U.S. Department of Housing and Urban Development (HUD) reported that 1 in 5 homeless people were over the age of 55. For seniors and other older adults, fixed incomes make it hard to battle the ever-increasing cost of expenses. Endhomelessness.org cites that 2.35 million older adults are paying over half of their limited income to rent. Based on Caring.com's July 2024 survey of seniors in the workforce , that's exactly why 1 in 15 retired seniors worry about losing their homes. Shelter use in homeless people older than 51 has gone up over 10% from 2007 to 2017, according to the HUD. But luckily, so has the number of shelters. Between 2022 and 2023, the HUD reports that emergency shelters added 28,760 more beds in emergency shelters, though this is a reduction in the amount of beds available during the thick of the COVID-19 pandemic. What Is Emergency Housing? Emergency homeless assistance, or emergency housing, is a temporary solution. It's designed to provide shelter while those facing housing instability figure out their next step. Emergency housing for homeless seniors gives someone the immediate ability to remain housed and safely sheltered. Local nonprofits are often involved in placing people experiencing homelessness or housing instability into emergency shelters. Low-income seniors, seniors who are low on funds and might not make rent, or seniors who need to leave their homes for other reasons can use emergency housing. How To Find Emergency Housing For Seniors Many cities have their own emergency housing programs. There are also nationwide programs that provide emergency housing for seniors. The internet is the fastest tool for locating local emergency housing. Libraries have free internet access, for those who might not have a computer or Wi-Fi to begin their search. The list below leads to websites that include phone numbers for emergency homeless assistance. Senior Programs for Emergency Housing Crisis Hotline 2-1-1 Seniors in need of immediate assistance and resources should call 2-1-1 or contact the United Way online . The 2-1-1 crisis hotline partners with United Way, which is committed to helping homeless seniors find local shelters or access transitional housing. The service can also connect seniors with other resources, including food, mental health support, or funding for health care expenses. Calling 2-1-1 is often required as a prerequisite before trying to get into a shelter or obtaining other assistance. Eligibility information Because 2-1-1 is for people in crisis, there are no eligibility requirements. However, some programs seniors may access through 2-1-1 do have eligibility requirements. Application information Seniors can simply dial 2-1-1 from nearly anywhere in the U.S. to be put in touch with the programs and resources they need. Housing Choice Voucher Program Designed specifically for seniors, people with disabilities, and low-income families, the Housing Choice Voucher Program is a federal program offering low-income housing options and rent assistance. These vouchers are available through your local public housing agency (PHA). This program enables and encourages participants to choose their own housing. Housing options don't need to be a part of subsidized housing projects, but there are limits on unit size. Typically, participants must pay 30% of their monthly adjusted income towards their rent, and the voucher program pays the remainder. Eligibility information Applicant income and family size help the PHA determine eligibility. Citizenship and eligible immigration status also play a factor. The family's income cannot exceed 50% of the median income for the county or metropolitan area where they're applying to live. Of the vouchers, 75% must go to people whose income is at or less than 30% of their area's median income. Application information Contact your local public housing agency . Section 202 Supportive Housing for the Elderly Program The Section 202 program helps expand the supply of affordable housing with supportive services for seniors. This program gives low-income seniors options that allow them to live independently, with support for cooking, cleaning, transportation, etc. Eligibility information This program is open to any very low-income household that has at least one person 62 years old or older. Application information Applicants must submit an application in response to a Notice of Funding Availability (NOFA) posted on Grants.gov . U.S Department of Housing and Urban Development-VA Supportive Housing Voucher (HUD-VASH) The HUD-VASH program was created as emergency homeless assistance for veterans. Its goal is to give homeless veterans access to permanent housing through public housing authorities. Veterans receive rental assistance through the HUD Housing Choice Voucher program and additional case management services through the VA. By December 2023, the HUD had allocated nearly 112,000 vouchers to help house veterans nationwide. To help veterans achieve stability and remain housed, VA case managers may connect veterans with support services such as health care, mental health treatment, and substance use counseling. Eligibility information If you or your loved one is a low-income senior with eligible military service, you may apply. Your local VA can tell you if your service qualifies you for HUD-VASH. Application information Senior veterans may apply online or call (877) 424-3838. Emergency Housing Resources by State Click here to learn more about the emergency housing options for seniors available in your state. The Bottom Line Low-income seniors who aren't in assisted living or independent living communities might find themselves facing housing instability. Emergency housing for seniors can help you or your loved one seek shelter. Crisis hotlines and public housing agencies can offer support. Senior Emergency Housing FAQ How long does it take to find emergency senior housing? Finding emergency housing for seniors depends heavily on your area. The first step is to call the Crisis Hotline at 2-1-1. Finding a shelter takes less time than applying and getting approved for low-income housing voucher programs. The 2-1-1 hotline can direct you to local resources and locators. Is there a limit to how long a senior can live in emergency housing? Yes and no. The duration depends on the type of housing. Shelters have limits that vary. Some shelters allow people to stay for up to six months, though that can vary based on demand. Seniors can remain in Section 202 supportive housing as long as they meet age and income requirements. Is there additional assistance for disabled seniors facing homelessness? Yes. Many counties have financial emergency programs that help seniors handle home repairs or short-term financial crises like utility shutoff. These programs allow the senior to focus their funds on their rent or mortgage. This story was produced by Caring.com and reviewed and distributed by Stacker Media. ShotPrime Studio // Shutterstock Get Government & Politics updates in your inbox!
NEW YORK (AP) — A number of President-elect Donald Trump 's most prominent Cabinet picks and appointees have been targeted by bomb threats and “swatting attacks," Trump's transition team said Wednesday. The FBI said it was investigating. “Last night and this morning, several of President Trump’s Cabinet nominees and Administration appointees were targeted in violent, unAmerican threats to their lives and those who live with them," Trump transition spokesperson Karoline Leavitt said in a statement. She said the attacks ranged from bomb threats to swatting, in which attackers initiate an emergency law enforcement response against a target victim under false pretenses. The tactic has become a popular one in recent years. Leavitt said law enforcement and other authorities acted quickly to ensure the safety of those who were targeted and Trump and his transition team are grateful. Among those targeted were New York Rep. Elise Stefanik, Trump’s pick to serve as the next ambassador to the United Nations ; Matt Gaetz, Trump’s initial pick to serve as attorney general ; and former New York congressman Lee Zeldin, who has been tapped to lead the Environmental Protection Agency. Law enforcement officials are also looking into whether Susie Wiles, Trump’s incoming chief of staff, and Pam Bondi, the former Florida attorney general whom Trump has chosen as Gaetz’s replacement, and other incoming administration officials were also victims — as well as how each was targeted, according to a law enforcement official who spoke on condition of anonymity as the investigation continues. Wiles and Bondi did not immediately respond to requests for comment. The FBI said in a statement that it was “aware of numerous bomb threats and swatting incidents targeting incoming administration nominees and appointees" and was investigating with its law enforcement partners. The FBI added: "We take all potential threats seriously, and as always, encourage members of the public to immediately report anything they consider suspicious to law enforcement.” White House spokesperson Saloni Sharma said President Joe Biden had been briefed and the White House is in touch with federal law enforcement and Trump's transition team. Biden “continues to monitor the situation closely," Sharma said, adding the president and his administration “condemn threats of political violence.” Stefanik's office said that, on Wednesday morning, she, her husband, and their 3-year-old son were driving home from Washington for Thanksgiving when they were informed of a bomb threat to their residence in Saratoga County. Her office said “New York State, County law enforcement, and U.S. Capitol Police responded immediately with the highest levels of professionalism.” The New York State Police said a team was dispatched to sweep Stefanik’s home on Wednesday morning in response to the bomb threat but did not locate any explosive devices. The agency directed further questions to the FBI. Zeldin said in a social media post that he and his family had been threatened. “A pipe bomb threat targeting me and my family at our home today was sent in with a pro-Palestinian themed message,” he wrote on X . “My family and I were not home at the time and are safe. We are working with law enforcement to learn more as this situation develops.” Police in Suffolk County, Long Island, said emergency officers responded to a bomb threat Wednesday morning at an address listed in public records as Zeldin’s home and were checking the property. In Florida, the Okaloosa County sheriff’s office said on Facebook that it “received notification of a bomb threat referencing former Congressman Matt Gaetz’s supposed mailbox at a home in the Niceville area" around 9 a.m. Wednesday. While a family member resides at the address, the office said, Gaetz “is NOT a resident.” No threatening devices were found. Gaetz was Trump’s initial pick to serve as attorney general, but he withdrew from consideration after allegations that he paid women for sex and slept with underage women. Gaetz has vehemently denied any wrongdoing and said last year that a Justice Department investigation into sex trafficking allegations involving underage girls had ended with no federal charges against him. The threats follow a political campaign marked by disturbing and unprecedented violence. In July, a gunman opened fire at a Trump rally in Butler, Pennsylvania, grazing the then-candidate in the ear with a bullet and killing one of his supporters. The Secret Service later thwarted a subsequent assassination attempt at Trump's West Palm Beach, Florida, golf course when an agent spotted the barrel of a gun poking through a perimeter fence while Trump was golfing. Trump was also the subject of an Iranian murder-for-hire plot , with a man saying he had been tasked with planning the assassination of the Republican president-elect. Also this week, authorities arrested a man they say posted videos on social media threatening to kill Trump, according to court documents. In one video posted on Nov. 13, Manuel Tamayo-Torres threatened to shoot the former president while holding what appeared to be an AR-15 style rifle, authorities said Among the other videos he posted was one from an arena in Glendale, Arizona on Aug. 23, the same day Trump held a campaign rally there, according to court papers. An attorney for Tamayo-Torres did not immediately respond to a request for comment Wednesday. Public figures across the political spectrum have been targeted in recent years by hoax bomb threats and false reports of shootings at their homes. About a year ago the FBI responded to an uptick in such incidents at the homes of public officials, state capitols and courthouses across the country around the holidays. Many were locked down and evacuated in early January after receiving bomb threats. No explosives were found and no one was hurt. Some of those targeted last year were Georgia Lt. Gov. Burt Jones, Boston Mayor Michelle Wu and Ohio Attorney General Dave Yost. In Wu’s case, a male caller told police he had shot his own wife and tied another man up. When police and EMT responders arrived at the address given by the caller, they quickly realized it was the Boston mayor’s home. Wu, a Democrat, has also been targeted by many swatting calls since she took office in 2021. The judges overseeing the civil fraud case against Trump in New York and the criminal election interference case against him in Washington were both targeted earlier this year. Justice Department special counsel Jack Smith, who recently abandoned the two criminal cases he brought against Trump, was also the subject of a fake emergency call on Christmas Day last year. Earlier this year, schools, government buildings and the homes of city officials in Springfield, Ohio, received a string of hoax bomb threats after Trump falsely accused members of Springfield’s Haitian community of abducting and eating cats and dogs. And in 2022, a slew of historically Black colleges and universities nationwide were targeted with dozens of bomb threats, with the vast majority arriving during the celebration of Black History Month. The U.S. Capitol Police said in a statement Wednesday that anytime a member of Congress is the victim of a swatting' incident, “we work closely with our local and federal law enforcement partners.” The force declined to provide further details, in part to “minimize the risk of copy-cats.” Republican House Speaker Mike Johnson called the threats “dangerous and unhinged.” “This year, there was not just one but TWO assassination attempts on President Trump," he wrote on X . “Now some of his Cabinet nominees and their families are facing bomb threats.” He added: “It is not who we are in America.” ___ Richer reported from Washington. Associated Press writers Colleen Long and Eric Tucker in Washington, Scott Bauer in Madison, Wisconsin, and Anthony Izaguirre in Albany, New York, contributed to this report.NoneVoters in Ireland were more than usually busy in 2024, casting their ballot in five different polls – for two referenda in March, local and European ballots in June and a general election in November. The country’s political comings and goings were further punctuated by an emotional announcement in March from former premier Leo Varadkar that he was resigning as taoiseach and Fine Gael leader. He was succeeded the following month in both roles by Simon Harris. But the year had so much more to offer than just politics, and PA news agency photographers were on hand to capture some of the highlights.
No. 8 Kentucky flying high ahead of Western Kentucky meetingNone
Charles & Colvard, Ltd. Receives Non-Compliance Letter from NasdaqNone
WOBURN, Mass., Nov. 21, 2024 (GLOBE NEWSWIRE) -- Replimune Group, Inc. (NASDAQ: REPL), a clinical stage biotechnology company pioneering the development of novel oncolytic immunotherapies, today announced that it has submitted a biologics license application (BLA) to the FDA for RP1 (vusolimogene oderparepvec) in combination with nivolumab for the treatment of adult patients with advanced melanoma who have previously received an anti-PD1 containing regimen. The submission was made under the Accelerated Approval pathway. The Company also announced that the FDA has granted Breakthrough Therapy designation to RP1 in combination with nivolumab in the same setting. Breakthrough Therapy designation is intended to expedite the development and review of therapies for serious diseases when preliminary clinical evidence indicates that the therapy may provide substantial improvement over existing available therapies on one or more clinically significant endpoints. This Breakthrough Therapy designation is based on the safety and clinical activity observed in the anti-PD1 failed melanoma cohort of the IGNYTE clinical trial. “Today is an important milestone for Replimune and for the melanoma community as we are one step closer to having another potential treatment available for patients who have limited options after progressing on anti-PD1 containing regimens,” said Sushil Patel, Ph.D., CEO of Replimune. The confirmatory Phase 3 IGNYTE-3 trial of RP1 in combination with nivolumab in advanced melanoma patients who have progressed on anti-PD1 and anti-CTLA-4 therapy, or who are not candidates for anti-CTLA-4 treatment is currently enrolling patients. For more information, visit https://replimune.com/clinical-trials/ignyte-3/ . About RP1 RP1 (vusolimogene oderparepvec) is Replimune’s lead product candidate and is based on a proprietary strain of herpes simplex virus engineered and genetically armed with a fusogenic protein (GALV-GP R-) and GM-CSF, intended to maximize tumor killing potency, the immunogenicity of tumor cell death, and the activation of a systemic anti-tumor immune response. About Replimune Replimune Group, Inc., headquartered in Woburn, MA, was founded in 2015 with the mission to transform cancer treatment by pioneering the development of novel oncolytic immunotherapies. Replimune’s proprietary RPx platform is based on a potent HSV-1 backbone intended to maximize immunogenic cell death and the induction of a systemic anti-tumor immune response. The RPx platform is designed to have unique dual local and systemic activity consisting of direct selective virus-mediated killing of the tumor resulting in the release of tumor derived antigens and altering of the tumor microenvironment to ignite a strong and durable systemic response. The RPx product candidates are expected to be synergistic with most established and experimental cancer treatment modalities, leading to the versatility to be developed alone or combined with a variety of other treatment options. For more information, please visit www.replimune.com . Forward Looking Statements This press release contains forward looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, including statements regarding our belief regarding the effect that the breakthrough designation will have on the timing and development of RP1 and other statements identified by words such as “could,” “expects,” “intends,” “may,” “plans,” “potential,” “should,” “will,” “would,” or similar expressions and the negatives of those terms. Forward-looking statements are not promises or guarantees of future performance, and are subject to a variety of risks and uncertainties, many of which are beyond our control, and which could cause actual results to differ materially from those contemplated in such forward-looking statements. These factors include risks related to our limited operating history, our ability to generate positive clinical trial results for our product candidates, the costs and timing of operating our in-house manufacturing facility, the timing and scope of regulatory approvals, the availability of combination therapies needed to conduct our clinical trials, changes in laws and regulations to which we are subject, competitive pressures, our ability to identify additional product candidates, political and global macro factors including the impact of the coronavirus as a global pandemic and related public health issues and the Russian-Ukrainian and Israel-Hamas political and military conflicts, and other risks as may be detailed from time to time in our Annual Reports on Form 10-K and Quarterly Reports on Form 10-Q and other reports we file with the Securities and Exchange Commission. Our actual results could differ materially from the results described in or implied by such forward-looking statements. Forward-looking statements speak only as of the date hereof, and, except as required by law, we undertake no obligation to update or revise these forward-looking statements. Investor Inquiries Chris Brinzey ICR Healthcare 339.970.2843 chris.brinzey@westwicke.com Media Inquiries Arleen Goldenberg Replimune 917.548.1582 media@replimune.com