NEW YORK (AP) — Kaapo Kaako scored a power-play goal with 24 seconds left, and the New York Rangers stopped a five-game slide by topping the Montreal Canadiens 4-3 on Saturday. Artemi Panarin, Vincent Trocheck and Mika Zibanejad also scored for the Rangers, who got their first win since a 4-3 victory at Vancouver on Nov. 19. Adam Fox had two assists, and Jonathan Quick made 25 saves. With Montreal’s Kirby Dach serving a four-minute, high-sticking penalty, Kaako got his fourth goal of the season. The Canadiens trailed 3-1 after two periods. But Cole Caufield scored his 14th goal 4:16 into the third and Nick Suzuki tied it at 14:07. Trocheck tipped the puck past Montreal goaltender Sam Montembeault at 19:56 to put New York ahead after Panarin and Montreal’s Mike Matheson scored earlier in the first. Panarin put the Rangers ahead at 9:02, scoring on a 5-on-3 for New York’s first power-play goal since Nov. 12 at home against Winnipeg. Matheson tied it at 11:47. Montembault made 24 saves for Montreal. Takeaways Canadiens: dropped to 3-7-1 on the road. Rangers: Forwards Chris Kreider and Filip Chytil returned to the lineup. Kreider missed three games with an upper-body injury while Chytil was out for seven after colliding with teammate K’Andre Miller on Nov. 14. Reilly Smith and Jonny Brodzinski were scratched. RELATED COVERAGE Predators trade Wedgewood to Avalanche for Annunen in swap of backup goaltenders Mason Marchment has two goals and assist as Stars beat Avalanche 5-3 Ryan Nugent-Hopkins scores in OT to lift Oilers to 4-3 win over Utah Key moment Seeking an early spark, New York captain Jacob Trouba fought Montreal’s Josh Anderson 1:58 into the contest. It appeared to give the Rangers a collective jolt that was missing in recent games. Key stat The Rangers are 11-1-0 when scoring first. It was the 1,700th home win in franchise history. Up next The Canadiens visit the Boston Bruins on Sunday. The Rangers host the New Jersey Devils on Monday. ___ AP NHL: https://apnews.com/hub/NHL
In the current Premier League season, the top players have been showcasing their skills on the pitch, with dribbling being a key aspect of their gameplay. The average successful dribbles per game rankings have revealed some impressive performances, with some players standing out from the rest.Britt Baker says she’s ‘exhausted’ by social media critics: ‘I’m done being polite’One of the highlights of the event was the presentation by representatives from the U.S. Weir Data School, who shared insights into their innovative educational approach and the benefits of international collaboration in preparing students for an increasingly interconnected world. The signing ceremony of the strategic cooperation agreement between Garden International High School and Weir Data School was met with great excitement and anticipation, symbolizing a new chapter of academic excellence and cultural exchange for both institutions.
As South Korea grapples with the fallout from the corruption scandal involving Cho Kuk and his family, the National Assembly's decision to call for his swift arrest has brought to the forefront important issues of transparency, accountability, and the rule of law. It remains to be seen how the government, the judiciary, and the public will navigate this complex and contentious situation in the days and weeks ahead.Cameron Haffner helps Evansville end five-game skid with 57-40 victory over Missouri StateNEW YORK (AP) — Kaapo Kaako scored a power-play goal with 24 seconds left, and the New York Rangers stopped a five-game slide by topping the Montreal Canadiens 4-3 on Saturday. Artemi Panarin, Vincent Trocheck and Mika Zibanejad also scored for the Rangers, who got their first win since a 4-3 victory at Vancouver on Nov. 19. Adam Fox had two assists, and Jonathan Quick made 25 saves. Javascript is required for you to be able to read premium content. Please enable it in your browser settings. Get updates and player profiles ahead of Friday's high school games, plus a recap Saturday with stories, photos, video Frequency: Seasonal Twice a week
New era in amphibian biology November 26, 2024 Institute of Science and Technology Austria Amphibians hold a significant place in evolution, representing the transition from aquatic to terrestrial lifestyles. They are crucial for understanding the brain and spinal cord of tetrapods -- animals with four limbs, including humans. A group of scientists now shows how harmless viruses can be used to illuminate the development of the frog nervous system. Facebook Twitter Pinterest LinkedIN Email Amphibians hold a significant place in evolution, representing the transition from aquatic to terrestrial lifestyles. They are crucial for understanding the brain and spinal cord of tetrapods -- animals with four limbs, including humans. A group of scientists led by a team at the Institute of Science and Technology Austria (ISTA) now shows how harmless viruses can be used to illuminate the development of the frog nervous system. The results have now been published in Developmental Cell . Virus. When you hear the word, you probably shudder. But not all viruses are bad or cause disease. Some are even used for therapeutic applications or vaccination. In basic research, they are often employed to infect certain cells, genetically modify them, or visualize neurons in the organism's central nervous system (CNS) -- the command center made up of the brain, spinal cord, and nerves. The highlighting process now finally works in amphibians. This has been shown in a new study by an international EDGE consortium jointly led by the Sweeney Lab at the Institute of Science and Technology Austria (ISTA) and the Tosches Lab at Columbia University. The researchers established a new technique that uses adeno-associated viruses (AAVs) to track a frog's nervous system throughout its metamorphosis -- a developmental transition from the early tadpole stages to its adult form. A breakthrough that can help usher amphibian neurobiology into a new era. Swimming vs. walking David Vijatovic and Lora Sweeney enter a laboratory full of water tanks. Vijatovic taps on one of them. Inside, a small mottled greenish-brown African clawed frog (Xenopus laevis) appears. Its limbs are prominent, gracefully maneuvering and gripping its surroundings. In another tank, tadpoles are swirling around using simple swimming motions. It is remarkable to think that one transforms into the other. "Frogs undergo metamorphosis," Sweeney says, "making them a great model organism for studying the transition between two movement modes -- swimming and walking." A frog's development spans over 12 to 16 weeks, giving scientists time to study each stage. During these weeks, a frog embryo develops to a young tadpole, a tadpole with two legs, and a young froglet with four legs before reaching the adult stage. "By looking at the several stages of development, we can investigate these locomotive behaviors and the underlying changes in the nervous system," Vijatovic adds. Just like an electrical circuit: how frogs are wired An organism's nervous system is referred to as the neural circuit because it resembles an electrical circuit. "Nerve cells (neurons) are connected to other neurons, transmitting electrical information. How we behave, what we sense, and how we interact with the world are the product of the way our neurons communicate with each other within these circuits," explains Sweeney. The critical piece is how the circuit is wired. We know that neurons are connected but which neuron connects to which? Which other cells does a single cell talk to, and what messages does it convey? To know more about this wiring, researchers have been using viruses, proven to be a powerful tool. Adeno-associated viruses (AAVs) are ideal in that regard. They are non-pathogenic while being able to infect a wide range of cell types, including neurons. AAVs can be modified to glow in bright green fluorescent colors under the microscope as they travel along neurons, whether in retrograde (backward, from the synapse toward the cell body) or anterograde (forward, from the cell body toward the synapse). In other words, AAVs can be used to illuminate the neural circuit from the broadcasting end to the receiving end or vice-versa. "This is a common technique used in neuroscience, especially in well-studied organisms like mice. For amphibians, it was thought that it could not be done," says Vijatovic. That was the general belief until now. The power of scientific collaboration To make AAV labeling work in amphibians, Sweeney and Vijatovic joined forces with an international team of scientists from Maria Tosches' group at Columbia University, where the study's other two co-first authors Eliza Jaeger and Astrid Deryckere are based. The consortium also included researchers from Tel Aviv University, the University of Utah, the Scripps Research Institute, and the California Institute of Technology. The researchers put their heads together, drew expertise from each other, visited conferences, had countless Zoom calls, and came up with different perspectives and ideas. "When you start researching an organism that is not yet well understood, it is great to have a community where you can share information," says Sweeney. They screened existing AAVs to find what was suitable for amphibians and optimized the infecting strategy eventually developing a "how-to guide" for frogs and newts. Vijatovic summarizes his PhD journey, "We started with young tadpoles, made our way to older tadpoles, and finally moved to juvenile and then adult frogs as well as adult newts. We tailored the tool to each life stage." Comparing frogs to humans: what this research says about us With this new technique, the scientists managed to apply AAVs for tracing neuron connections in amphibians. This will help them find out more about how the amphibian brain compares to that of mammals. Besides that, the new approach also opens doors to further analyzing neuronal development. With some of the screened AAV variants, the researchers can label progenitor cells at a specific point in time during the circuit's development and follow them to see what neurons they become. "This way, we can resolve the whole circuit by its development, see how it changes over time, and how the whole nervous system is built," Sweeney says. Although amphibians and mammals last shared a common ancestor about 360 million years ago, they share common traits. "By comparing the details of a frog's nervous system to a human's, we can see what we don't have and what we have," Sweeney continues. This knowledge can help us understand how the human nervous system became specialized over time. "The better we understand the basic building blocks of the nervous system, the more we understand how we can replace them during disease and injury." Story Source: Materials provided by Institute of Science and Technology Austria . Note: Content may be edited for style and length. Journal Reference : Cite This Page :Brand reputation and popularity also play a role in the pricing of down jackets. Well-known outdoor and sportswear brands often command higher prices based on their brand image, innovation, and technology. However, it is essential to note that paying a premium for a popular brand does not always guarantee superior quality or performance.
As the situation in Syria continues to evolve, it is clear that the conflict shows no signs of abating. The latest Israeli airstrikes have once again highlighted the precarious nature of the situation and the potential for further escalation. It is imperative that all parties involved in the conflict exercise restraint and prioritize diplomatic solutions to avoid further bloodshed and instability in the region.The 27-year-old achieved the feat with a 23-yard run during the fourth quarter of the Eagles’ crushing 41-7 success at Lincoln Financial Field. Barkley is 100 yards short of Eric Dickerson’s record of 2,105 yards, set in 1984 for the Los Angeles Rams, ahead of next week’s regular season finale against the New York Giants. Single-season rushing record in reach. @saquon @Eagles pic.twitter.com/iSHyXeMLv1 — NFL (@NFL) December 29, 2024 However, he could be rested for that game in order to protect him from injury ahead of the play-offs. The Tampa Bay Buccaneers kept alive their dreams of reaching the play-offs by overcoming the Carolina Panthers 48-14. Veteran quarterback Baker Mayfield produced a dominant performance at Raymond James Stadium, registering five passing touchdowns to equal a Buccaneers franchise record. he BAKED today 👨🍳 pic.twitter.com/eFX9fd1w5P — NFL (@NFL) December 29, 2024 The Buffalo Bills clinched the AFC conference number two seed for the post season with a 40-14 success over the New York Jets at Highmark Stadium. Josh Allen passed for 182 yards and two touchdowns, while rushing for another. Buffalo finish the 2024 regular season undefeated at home, with eight wins from as many games. The Indianapolis Colts’ hopes of reaching the play-offs were ended by a 45-33 defeat to the Giants. FINAL: Drew Lock accounts for 5 TDs in the @Giants victory! #INDvsNYG pic.twitter.com/N8HJYth09F — NFL (@NFL) December 29, 2024 Malik Nabers exploded for 171 yards and two touchdowns and Ihmir Smith-Marsette broke a 100-yard kick-off return to give the Giants their highest-scoring output under head coach Brian Daboll. Quarterback Drew Lock threw four touchdown passes and accounted for a fifth on the ground to seal the win. Elsewhere, Mac Jones threw two touchdowns to help the Jacksonville Jaguars defeat the Tennessee Titans 20-13, while the Las Vegas Raiders beat the New Orleans Saints 25-10.
NEW YORK (AP) — Kaapo Kaako scored a power-play goal with 24 seconds left, and the New York Rangers stopped a five-game slide by topping the Montreal Canadiens 4-3 on Saturday. Artemi Panarin, Vincent Trocheck and Mika Zibanejad also scored for the Rangers, who got their first win since a 4-3 victory at Vancouver on Nov. 19. Adam Fox had two assists, and Jonathan Quick made 25 saves. With Montreal’s Kirby Dach serving a four-minute, high-sticking penalty, Kaako got his fourth goal of the season. The Canadiens trailed 3-1 after two periods. But Cole Caufield scored his 14th goal 4:16 into the third and Nick Suzuki tied it at 14:07. Trocheck tipped the puck past Montreal goaltender Sam Montembeault at 19:56 to put New York ahead after Panarin and Montreal’s Mike Matheson scored earlier in the first. Panarin put the Rangers ahead at 9:02, scoring on a 5-on-3 for New York’s first power-play goal since Nov. 12 at home against Winnipeg. Matheson tied it at 11:47. Montembault made 24 saves for Montreal. Canadiens: dropped to 3-7-1 on the road. Rangers: Forwards Chris Kreider and Filip Chytil returned to the lineup. Kreider missed three games with an upper-body injury while Chytil was out for seven after colliding with teammate K’Andre Miller on Nov. 14. Reilly Smith and Jonny Brodzinski were scratched. Seeking an early spark, New York captain Jacob Trouba fought Montreal’s Josh Anderson 1:58 into the contest. It appeared to give the Rangers a collective jolt that was missing in recent games. The Rangers are 11-1-0 when scoring first. It was the 1,700th home win in franchise history. The Canadiens visit the Boston Bruins on Sunday. The Rangers host the New Jersey Devils on Monday. AP NHL: https://apnews.com/hub/NHLLululemon's Boxing Week scores end tonight — 13 bags we're shocked are still in stock, starting at $14"Shenkuu Motorsport" Series Brand Festival Kicks Off on Steam
TSB investigating rough plane landing in Halifax, passenger says flames were visible