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The standard Lorem Ipsum passage, used since the 1500s "Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum." Section 1.10.32 of "de Finibus Bonorum et Malorum", written by Cicero in 45 BC "Sed ut perspiciatis unde omnis iste natus error sit voluptatem accusantium doloremque laudantium, totam rem aperiam, eaque ipsa quae ab illo inventore veritatis et quasi architecto beatae vitae dicta sunt explicabo. Nemo enim ipsam voluptatem quia voluptas sit aspernatur aut odit aut fugit, sed quia consequuntur magni dolores eos qui ratione voluptatem sequi nesciunt. Neque porro quisquam est, qui dolorem ipsum quia dolor sit amet, consectetur, adipisci velit, sed quia non numquam eius modi tempora incidunt ut labore et dolore magnam aliquam quaerat voluptatem. Ut enim ad minima veniam, quis nostrum exercitationem ullam corporis suscipit laboriosam, nisi ut aliquid ex ea commodi consequatur? Quis autem vel eum iure reprehenderit qui in ea voluptate velit esse quam nihil molestiae consequatur, vel illum qui dolorem eum fugiat quo voluptas nulla pariatur?" To keep reading, please log in to your account, create a free account, or simply fill out the form below.PUZZLED BY MOTIVE Police were still puzzling over why the driver smashed a rented SUV at high speed through the crowd of revellers, bringing death and chaos to the festive event. Abdulmohsen had in his many online posts voiced strongly anti-Islam views, anger at German authorities and support for far-right conspiracy narratives on the "Islamisation" of Europe. Die Welt daily, citing unnamed security sources, reported that Abdulmohsen had been treated for a mental illness in the past, but this has not been confirmed by authorities. The Saudi suspect has been remanded in custody in a top-security facility on five counts of murder and 205 of attempted murder, prosecutors said, but not so far on terrorism-related charges. Even as the attacker's motive remained unclear, the attack has moved the flashpoint issues of security and immigration back to the centre of German politics ahead of the Feb 23 elections. The mass-circulation Bild Daily wrote that "although the background to the terrible attack in Magdeburg has not yet been clarified, it is already clear: there will be a 'before' and an 'after' in this election campaign". "WEAKEST LINK" Interior Minister Nancy Faeser has vowed that "no stone will be left unturned" in shedding light on what information had been available on Abdulmohsen in the past. She stressed that the attacker did "not fit any previous pattern" because "he acted like an Islamist terrorist although ideologically he was clearly an enemy of Islam". The Association of German Criminal Police Officers warned that "it is still too early to draw hasty conclusions or even to formulate political demands". German Christmas markets - among the country's most iconic and beloved festive events - have been specially secured since a jihadist attacker rammed a truck through one in Berlin in 2016, killing 13 people.
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WATERTOWN, Mass. , Dec. 5, 2024 /PRNewswire/ -- 3D BioLabs LLC ("3D BioLabs" or "3DB"), has reached a pivotal milestone in the field of regenerative medicine as recently published in the Proceedings of the National Academy of Sciences . 3DB's study has demonstrated a new approach to creating large organs to solve the organ transplant shortage. Using 3D printing, computational fluid dynamics, and organ specific cells, their study demonstrated effective blood flow and cell viability and function within the model device, marking a significant advance toward a bioengineered liver replacement. The study was led by 3D BioLabs Scientific Founder Dr. Joseph P. Vacanti , the Distinguished John Homans Professor of Surgery at Harvard Medical School and Mass General Hospital. 3D BioLabs 3D printed device (3DPD) has been engineered to mimic native liver tissue structure by using fractal architecture to support both vascular anastomosis and hepatocyte function. The device features embedded portal-venous (PV) channels that enable continuous blood flow when implanted and hepatobiliary (HB) channels that support the viability of liver cells. Active perfusion of tissue scaffolds allows for improved oxygen and nutrient availability to increase cell density, further supporting the feasibility of the device as a functional liver tissue substitute. Dr. Vacanti said: "We are extremely pleased to reach this pivotal milestone in the development of functioning 3D printed organs, which furthers our mission of solving the long-standing issue of organ transplant shortages. With our recent study, we are one step closer to achieving an engineered alternative to liver transplantation, addressing critical organ shortages and helping patients in need." 3DB's proprietary technology builds upon decades of work in tissue engineering, beginning with the first patent in tissue engineering granted to Dr. Vacanti in 1988 and the Vacanti ear mouse in 1997. This milestone is supported by recent work implanting large and complex devices into pigs for as long as one week. For further details, visit 3DBioLabs.com . About 3D BioLabs: 3D BioLabs is comprised of scientists, engineers and visionary clinical scientists that aim to improve world health by providing man made organs for individuals suffering from organ failure and other complex problems of tissue loss. Our mission is the development of a platform technology that will result in sophisticated designs that allow for precise mimicry of what happens inside humans more closely than other systems, where decades of research have reached barriers based on organ size and complexity. View original content to download multimedia: https://www.prnewswire.com/news-releases/3dbiolabs-achieves-pivotal-milestone-in-development-of-3d-printed-liver-implant-302324302.html SOURCE 3D BioLabsIf President-elect Donald Trump follows through on his pledge to deport millions of immigrants, it could upend the economies of states where farming and other food-related industries are crucial — and where labor shortages abound. Related Articles Immigrants make up of the nation’s crop farmworkers, according to the U.S. Department of Labor, and roughly 2 in 5 of them are not legally authorized to work in the United States. Agricultural industries such as meatpacking, dairy farms and poultry and livestock farms also rely heavily on immigrants. “We have five to six employees that do the work that nobody else will do. We wouldn’t survive without them,” said Bruce Lampman, who owns Lampman Dairy Farm, in Bruneau, Idaho. His farm, which has been in the family three decades, has 350 cows producing some 26,000 pounds of milk a day. “My business and every agriculture business in the U.S. will be crippled if they want to get rid of everybody who does the work,” said Lampman, adding that his workers are worried about what’s to come. Anita Alves Pena, a Colorado State University professor of economics who studies immigration, noted that many agricultural employers already can’t find enough laborers. Without farm subsidies or other protections to make up for the loss of immigrant workers, she said, the harm to state economies could be significant. “Farmers across the country, producers in a lot of different parts, are often talking about labor shortages — and that’s even with the current status quo of having a fairly high percentage of unauthorized individuals in the workforce,” Pena said. “A policy like this, if it was not coupled with something else, would exacerbate that.” Employers have a hard time hiring enough farm laborers because such workers generally are paid low wages for arduous work. In addition to hiring immigrant laborers who are in the country illegally, agricultural employers rely on the federal H-2A visa program. H-2A visas usually are for seasonal work, often for . However, they can be extended for up to before a worker must return to their home country. Employers must pay H-2A workers a state-specific minimum wage and provide no-cost transportation and housing. Still, employers’ applications for H-2A visas have soared in the past 18 years, according to the U.S. Department of Agriculture, a trend the shortage of U.S.-born laborers willing to do the work. The number of H-2A positions has surged from just over 48,000 in 2005 to more than 378,000 in 2023. But agricultural employers that operate year-round, such as poultry, dairy and livestock producers, can’t use the seasonal visa to fill gaps, . Farmers also employ foreign nationals who have “temporary protected status” under a 1990 law that allows immigrants to remain if the U.S. has determined their home countries are unsafe because of violence or other reasons. There are people in the U.S. under the program or eligible for it, from countries including El Salvador, Ethiopia, Haiti, Honduras, Lebanon and Ukraine. Many have been here for decades, and Trump has threatened to end the program. Immigration advocates want a pathway for H-2A workers to gain permanent legal status, and agricultural trade organizations are pushing for an expansion of the H-2A program to include year-round operations. The National Milk Producers Federation says it’s too early to say how it would cope with mass deportations under the Trump administration. But the group it “strongly supports efforts to pass agriculture labor reform that provides permanent legal status to current workers and their families and gives dairy farmers access to a workable guestworker program.” Immigrants make up 51% of labor at dairy farms across states, and farms that employ immigrants produce nearly 80% of the nation’s milk supply, according to the organization. “Foreign workers are important to the success of U.S. dairy, and we will work closely with members of Congress and federal officials to show the importance of foreign workers to the dairy industry and farm communities,” Jaime Castaneda, the group’s executive vice president for policy development and strategy, wrote in an email. Adam Croissant, the former vice president of research and development at yogurt company Chobani, which has manufacturing plants in Idaho and New York, said he’s seen a lot of misinformation around immigrants’ workforce contributions. “The dairy industry as a whole understands that without immigrant labor, the dairy industry doesn’t exist. It’s as simple as that,” said Croissant. Tom Super, a spokesperson for the National Chicken Council, lambasted U.S. immigration policy and said the poultry industry “wants a stable, legal, and permanent workforce.” “The chicken industry is heavily affected by our nation’s immigration policy or, more pointedly, lack thereof. ... The system is broken, and Washington has done nothing to fix it,” Super wrote in an email. But major changes to the H-2A visa program are unlikely to happen before deportations begin. In with NBC News’ “Meet the Press” last weekend, Trump repeated his promise to start deporting some immigrants almost immediately. He said he plans to begin with convicted criminals, but would then move to other immigrants. “We’re starting with the criminals, and we’ve got to do it. And then we’re starting with the others, and we’re going to see how it goes.” Some farmers still hope that Trump’s actions won’t match his rhetoric. But “hoping isn’t a great business plan,” said Rick Naerebout, CEO of the Idaho Dairymen’s Association. “Our ability to feed ourselves as a country is completely jeopardized if you do see the mass deportations.” If the deportations do happen, agricultural workers will disappear faster than they can be replaced, experts say. “The H-2A program will not expand instantly to fill the gap. So, that’s going to be a problem,” said Jeffrey Dorfman, a professor of agricultural economics at North Carolina State University who was Georgia’s state economist from 2019 to 2023. In Georgia, agriculture is an that supports more than 323,000 jobs. It is one of the five states most reliant on the federal H-2A visa program, depending on those workers to fill of agricultural jobs. Dorfman argued that even the fear of deportation will have an impact on the workforce. “When farmworkers hear about ICE [U.S. Immigration and Customs Enforcement] raids on a nearby farm, lots of them disappear. Even the legal ones often disappear for a few days. So, if everybody just gets scared and self-deports, just goes back home, I think that would be the worst disruption,” said Dorfman, adding that even more jobs would need to be filled if the administration revokes temporary protected status. Antonio De Loera-Brust, communications director for the farmworker labor union United Farm Workers, said the nation’s focus should be on protecting workers, no matter their legal status. “They deserve a lot better than just not getting deported,” he said. “They deserve better wages, they deserve labor rights, they deserve citizenship.” And though economists and the agriculture industry have said that mass deportations could raise grocery store prices, De Loera-Brust called that particular argument a sign of “moral weakness.” “As if the worst thing about hundreds of thousands of people getting separated from their families was going to be that consumers would have to pay more for a bag of strawberries or a bag of baby carrots,” De Loera-Brust said. “There’s a moral gap there.” ©2024 States Newsroom. Visit at stateline.org. Distributed by Tribune Content Agency, LLC.
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BERKELEY HEIGHTS, N.J., Dec. 05, 2024 (GLOBE NEWSWIRE) -- Cyclacel Pharmaceuticals, Inc. (NASDAQ: CYCC, NASDAQ: CYCCP; "Cyclacel" or the "Company"), a biopharmaceutical company developing innovative cancer medicines, today announced that it is in the process of exploring and reviewing strategic alternatives on an expedited basis in order to preserve the Company’s cash, including a potential transaction with investor David Lazar of Activist Investing, LLC, which transaction would be subject to the consent of an existing securityholder. The Company’s Board of Directors is reviewing a range of appropriate strategies to realize value from its assets. The Board has directed management to reduce operating costs while such alternatives are being explored. There can be no assurance that the exploration of strategic alternatives will result in any agreement or transaction, or as to the timing of any such agreement or transaction. Further, there can be no assurance that the Company will be able to reach an agreement, or consummate a transaction, with Mr. Lazar or receive the required consent of an existing securityholder to any such transaction. As previously disclosed, the Company does not presently meet the continued listing requirements of the Nasdaq Stock Market and its securities would be subject to delisting if the Company fails to regain compliance during the required compliance period. In the event that the Company is not able to enter into a strategic transaction and/or secure additional funding, it may be forced to cease all business operations. In such event, the Company’s stockholders may lose a part or all of their investment in the Company. About Cyclacel Pharmaceuticals, Inc. Cyclacel is a clinical-stage, biopharmaceutical company developing innovative cancer medicines based on cell cycle, transcriptional regulation and mitosis biology. The transcriptional regulation program is evaluating fadraciclib, a CDK2/9 inhibitor, and the anti-mitotic program plogosertib, a PLK1 inhibitor, in patients with both solid tumors and hematological malignancies. Cyclacel's strategy is to build a diversified biopharmaceutical business based on a pipeline of novel drug candidates addressing oncology and hematology indications. For additional information, please visit www.cyclacel.com . Forward-looking Statements This news release contains certain forward-looking statements that involve risks and uncertainties that could cause actual results to be materially different from historical results or from any future results expressed or implied by such forward-looking statements. Such forward-looking statements include, among other things, statements related to the Company’s exploration and review of strategic alternatives, its ability to identify and complete a transaction as a result of the strategic review process, including a potential transaction with David Lazar, its plans to reduce costs and conserve cash and Cyclacel’s ability to regain and maintain compliance with Nasdaq’s continued listing requirements. You are urged to consider statements that include the words "may," "will," "would," "could," "should," "believes," "estimates," "projects," "potential," "expects," "plans," "anticipates," "intends," "continues," "forecast," "designed," "goal," or the negative of those words or other comparable words to be uncertain and forward-looking. These risks and uncertainties include the risk that the Company may not be successful in exploring strategic alternatives and consummating one or more strategic transactions on attractive terms, if at all; the Company’s actual reductions in spending as compared to anticipated cost reductions; the Company’s costs of continuing to operate as a public company; and the other risks described more fully in Cyclacel Pharmaceuticals’ filings with the Securities and Exchange Commission, including the “Risk Factors” section of the Company’s Annual Report on Form 10-K for the year ending December 31, 2023 and its other documents subsequently filed with or furnished to the Securities and Exchange Commission, including its Form 10-Q for the quarter ended September 30, 2024. For a further list and description of the risks and uncertainties the Company faces, please refer to our most recent Annual Report on Form 10-K and other periodic and other filings we file with the Securities and Exchange Commission and are available at www.sec.gov . Such forward-looking statements are current only as of the date they are made, and we assume no obligation to update any forward-looking statements, whether as a result of new information, future events or otherwise. Contacts Company: Paul McBarron, (908) 517-7330, IR@cyclacel.com © Copyright 2024 Cyclacel Pharmaceuticals, Inc. All Rights Reserved. The Cyclacel logo and Cyclacel® are trademarks of Cyclacel Pharmaceuticals, Inc.FTC Settles with Companies Over Sale of Sensitive Data
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TOPEKA, Kan. — U.S. Rep. Jake LaTurner marked final preparations for departing Congress with a speech connecting his rise in Kansas politics to a family legacy of resilience and featuring a special request that colleagues aid children suffering extreme malnutrition. LaTurner, 36, a Republican who served in the Kansas Senate and as state treasurer before entering the U.S. House, declined to seek reelection to a third term in 2024. He was elected in 2020 by 2nd District voters eager to replace troubled GOP U.S. Rep. Steve Watkins. He said in April the requirements of serving in Congress and running for reelection every two years had “taken a toll.” A native of Galena, Kansas, and a graduate of Pittsburg State University, he has four children and wanted to “be more present” for them. “I want to thank my friends both at home and my colleagues here, my supporters who helped me get here, and my family,” LaTurner said. “To my kids, the best title I’ve ever had is dad. And that title is about to get my full attention.” In remarks offered on the House floor ahead of his January exit, LaTurner requested Congress and the White House approve $300 million in funding for a global health initiative making use of Ready-to-Use Therapeutic Foods, or RUTF. It would expand the reach of this U.S.-made, medical-grade, nutrient-dense paste given to children suffering severe malnutrition. “That increase should be realized. It is the right thing to do,” LaTurner said. LaTurner said starving children consuming RUTF — at a cost of about $1 per day — had a survival rate near 90%. The nutritional product could be made with ingredients from 28 states, including peanuts, dairy, soy, sugar and micronutrients. He recalled entering the House in 2021 and speaking with U.S. Rep. Don Young, who became the longest-serving Republican in House history. Young represented Alaska until his death in 2022. “He told me when he arrived in 1973, it was customary for freshmen members to wait six months before speaking on the House floor,” LaTurner said. “To his surprise, I adopted this tradition. I did so partly out of deference to the dean, but mostly because it showed respect for this institution.” LaTurner said it was the responsibility of people serving in Congress to preserve “an institution and a system of government that our founders painstakingly designed to safeguard against human nature.” The departing Republican originally said he followed a path carved through sacrifice and tenacity of his family. LaTurner said his single-parent father worked long hours managing a Sonic restaurant while putting himself through college. His dad became the first in the family to earn a college degree. He was as an educator and mayor of Galena. His grandmother dropped out of school in the ninth grade because she had only one dress and couldn’t endure ridicule by her classmates. She raised six children and earned a GED before working as a nurse. LaTurner’s grandfather was the first in the family to graduate high school. He lost the sight in one eye while serving in Korea. Unable to pass a physical, he worked odd jobs until he found his calling as a lay judge. His grandfather’s father was killed in the mines at the age of 41 and left behind a widow and six children. They endured hardships most people cannot fathom, LaTurner said. “Yet three short generations later, his great-grandson was called ‘the gentleman from Kansas’ on the floor of the United States House of Representatives,” LaTurner said. “I share these stories because they remind me every day that I did not get here on my own. What a country this is. But it’s not just my story. It’s the American story.”
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China has revealed a chilling list of US naval targets it could look to strike should to two countries engage in a future conflict, according to a bombshell new report. The "hit list" was published in the state-supervised magazine Defence Industry Conversion and reportedly includes radars, sensors, and communication equipment. The report was authored by Mo Jiaqin, an expert in electronic countermeasures for the People's Liberation Army (PLA), who claimed the army could "hack" a major US Navy communication system. It includes details on how the PLA could hack into the US Navy's Cooperative Engagement Capability (CEC) system that shares defence resources between the entire fleet. The PLA said it could attack it with fake signals and "continuous access requests" that would "overwhelm" the electronic warfare system, according to the South China Morning Post . The report claims the army could mimick the "correct signaling method" to "infiltrate the CEC network as a cooperative unit and launch attacks". Jiaqin wrote: "Continuous access requests can be made to overwhelm one of the CEC nodes with identification tasks, disrupting its operation. "[The report can] provide references for the development of electronic countermeasures technology and related equipment in China's future naval battlefields." Jiaqin also detailed the CEC's strengths and weaknesses, arguing that its use of radars can be taken advantage of by foreign actors looking to interfere . She explained: "It [the CEC] is formed through the networking of phased array radars, which relies on wireless communication links. When the opposing force employs electronic interference, the wireless links are prone to disconnection or disruption." It is not yet known why this report was published and whether it will be taken seriously by the Chinese military in the event of a future conflict.Russian presence in Syria remains. But it's unclear for how long, the real-time strategy adventure from , is set to launch out of early access this summer [Southern Hemisphere], after three years in development. To celebrate the achievement, a has debuted in the latest PC Gaming Show, revealing more of the game’s upcoming multiplayer features, and every other change for its full release. As detailed, will be significantly updated in the coming months, with 1.0 improvements including “full co-operative multiplayer, allowing two players to unite, strategise, and push back the encroaching darkness together.” In addition to co-op multiplayer, the game also features a vast campaign mode where you’ll attempt to survive against roaming hordes of enemies, doing everything in your power to defend your armies. Your journey is complicated by a range of novel features: there’s a day and night cycle that forces you to change up your strategy on the fly, there’s fear mechanics that must be overcome, and the game’s proprietary SwarmTech engine also allows for up to 70,000 enemies to assault you in waves. That’s a whole lot of chopping, and it’ll certainly keep you on your toes. It’s more likely you’ll fall in your quest to survive, but that’s how is built. You do your best, and then a new run begins, complete with new blessings and malices to shake up the action. In our early access preview of , we were enamoured by the game’s campaign mode – and we’re certainly keen to see how it’s evolved since then, and how co-op elements add to gameplay elsewhere. “The game’s defence loop is surprisingly complex, and even in the opening chapters of , it leaves room for plenty of creativity, as well as a hefty dose of failure,” we wrote. “The opening act of sports a measured balance between frustrating challenge and rewarding victory, encouraging more creative and tactical approaches with each attempt to survive. Wits and quick thinking are needed to hit every goal post in this more guided narrative, but thankfully, each death feels meaningful – and effectively pushes you onward.” When launches, players will be able to hop into this campaign once more, while also experimenting with that highly coveted co-op mode. Stay tuned for more on this upcoming 1.0 update, which is set to land this season.
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