Chad Chronister, Donald Trump’s pick to run the DEA, withdraws name from considerationVANCOUVER, British Columbia, Dec. 13, 2024 (GLOBE NEWSWIRE) -- Rakovina Therapeutics Inc. (TSX-V: RKV, the " Company ”, " Rakovina ”, or " Rakovina Therapeutics ”) a biopharmaceutical company committed to advancing new cancer therapies based on novel DNA-damage response technologies is pleased to announce the closing of a $3.0 million private placement. The private placement consists of 50,000,000 units (the " Units ”) at a price of $0.06 per Unit. Each Unit consists of one common share of the Company (each, a " Common Share ”) and one Common Share purchase warrant (each, a " Warrant ”). Each Warrant entitles the holder thereof to subscribe for and purchase one Common Share of the Company for a period of 24 months from the date of issue at a price of $0.10 per Common Share. Rakovina retains the right to accelerate the Warrant exercise period if, upon written notice to the holder, the 20-day volume-weighted average price of its Common Shares exceeds $0.30. In connection with the Private Placement, the Company paid cash finder's fees to Canaccord Genuity Corp., Ventum Financial Corp., Haywood Securities Inc., Research Capital Corporation, Hampton Securities Limited, Ewing Morris & Co. Investment Partners Ltd. and Leede Financial Inc. (each a " Finder ”, and collectively, the " Finders ”) in the aggregate amount of $180,841 and issued a total of 3,021,872 non-transferable finder's warrants (each, a " Finder's Warrant ') to the Finders, in accordance with the policies of the TSX Venture Exchange (the " TSXV ”). Each Finder's Warrant entitles the holder thereof to subscribe for and purchase one Common share of the Company for a period of 24 months from the date of issue at a price of $0.10 per Common Share, subject to acceleration on the same terms as the Warrants issued in connection with the private placement. The private placement is subject to the final acceptance of the TSXV and all securities issuable in connection with the private placement are subject to a hold period of four months plus one day from the date of issuance, in accordance with applicable securities laws. The proceeds of the private placement will be used to accelerate both discovery and development of the Company's proprietary drug candidates, shortlisted from the Deep Docking and Variational AI platforms. "This overwhelming response from our investors underscores the strength of our science, the extraordinary talent and dedication of our team and the transformative potential of our therapies,” said Jeffrey Bacha, Executive Chairman of Rakovina Therapeutics. "We are deeply grateful for the trust placed in us and remain resolute in our mission to utilize leading AI technologies to develop innovative solutions for cancer care.” The Company extends its heartfelt thanks to its investors, partners, and team for their unwavering support as Rakovina continues its work to bring new hope to patients and families affected by cancer. Rakovina is pleased to announce its engagement of Fairfax Partners Inc. as its Investor Relations (IR) partner. With extensive expertise in investor engagement strategies, Fairfax will implement a comprehensive six-month IR program designed to enhance Rakovina's market presence and expand its investor base. The program, which includes an option to renew for an additional six months, focuses on complementing traditional IR efforts with targeted online marketing campaigns, activation of a robust social media influencer network, and collaboration with external consultants and global wealth management channels. These initiatives will support Rakovina's strategic plan for 2025 by institutionalizing its investor base and strengthening its distribution capabilities. Under the agreement, Fairfax will receive a monthly fee of $5,000 plus GST, a one-time setup fee of $15,000 plus GST, and a marketing budget of $120,000 plus GST, disbursed as follows: $80,000 upon signing and $40,000 two months later. Services provided by Fairfax include inbound and outbound phone communications, website and social media management, marketing material preparation, news release support, and roadshow assistance, ensuring Rakovina's IR efforts align with market expectations. Fairfax Partners Inc., located at 306-1238 Seymour Street, Vancouver, BC, confirms that neither its directors nor officers hold any securities of Rakovina. For inquiries, please contact [email protected] . "We are thrilled to partner with the seasoned team at Fairfax Partners to expand our investor base and increase awareness of Rakovina Therapeutics' vision. Fairfax's creative and forward-thinking approach to investor relations will be a critical asset as we enter a pivotal year. By harnessing their extensive network and digital expertise, we aim to significantly enhance our market presence and deliver lasting value to our shareholders,” said Mr. Bacha. About Rakovina Therapeutics Inc. Rakovina Therapeutics Inc. is dedicated to developing innovative cancer therapies targeting the DNA-damage response. The company has established a development pipeline of novel DNA-damage response inhibitors by leveraging Artificial Intelligence (AI) to accelerate the identification and optimization of drug candidates. Rakovina Therapeutics aims to advance one or more of these candidates into human clinical trials in collaboration with pharmaceutical partners and secure marketing approvals from Health Canada, the U.S. Food and Drug Administration, and other international regulatory agencies. Further information may be found at www.rakovinatherapeutics.com . The TSXV has neither approved nor disapproved the content of this press release. Neither the TSXV nor its Regulation Services Provider (as that term is defined in policies of the TSXV) accepts responsibility for the adequacy or accuracy of this release. Notice Regarding Forward-Looking Statements: This release includes forward-looking statements regarding the Company and its respective business, which may include, but is not limited to, statements with respect to the terms of the private placement, the closing of the private placement, the receipt of final TSXV approval, the proposed business plan of the Company; the Company's commitment to advancing new cancer therapies; the ability of the Company to extract value from its AI collaborations; the Company's ability to execute on its business plans while maintaining high standards of research; the ability of Pharma Inventor Inc. to accurately provide medicinal chemistry support; the projected timeline and effectiveness of the Company's strategy to utilize the Deep Docking AI platform; and the Company's ability to generate shareholder value. Often, but not always, forward-looking statements can be identified by the use of words such as "plans”, "is expected”, "expects”, "scheduled”, "intends”, "contemplates”, "anticipates”, "believes”, "proposes” or variations (including negative variations) of such words and phrases, or state that certain actions, events, or results "may”, "could”, "would”, "might” or "will” be taken, occur or be achieved. Such statements are based on the current expectations of the management of the Company. The forward-looking events and circumstances discussed in this release may not occur by certain specified dates or at all and could differ materially as a result of known and unknown risk factors and uncertainties affecting the Company, including risks regarding the medical device industry, economic factors, regulatory factors, the equity markets generally and risks associated with growth and competition. Although the Company has attempted to identify important factors that could cause actual actions, events, or results to differ materially from those described in forward-looking statements, there may be other factors that cause actions, events, or results to differ from those anticipated, estimated or intended. No forward-looking statement can be guaranteed. Except as required by applicable securities laws, forward-looking statements speak only as of the date on which they are made and the Company undertakes no obligation to publicly update or revise any forward-looking statement, whether as a result of new information, future events, or otherwise. The reader is referred to the Company's most recent filings on SEDAR for a more complete discussion of all applicable risk factors and their potential effects, copies of which may be accessed through the Company's profile page at www.sedar.com. For Further Information Contact: David Hyman, Chief Financial Officer [email protected] Invest Relations &Media Michelle Seltenrich [email protected] 778-773-5432
ST. PAUL — Kris Bolle is living the “van life” these days with Annie, his mini Australian shepherd. Bolle, 46, bought a 2020 Dodge Ram ProMaster cargo van this past fall. The Hayfield resident planned, essentially, a studio apartment inside. The van with a high roof has room for a full bed, a small kitchen area and a writing desk. He saves money by forgoing rent, but there is a cost — isolation. It’s a lifestyle he’s grown accustomed to since he had to hide his sexuality over the years, including in the Navy under the now-defunct “Don’t Ask, Don’t Tell” policy, which allowed gay and lesbian service members to stay in the military as long as they weren’t out, he said. “I had to be very, very tight-lipped about me ... so I’m used to it,” Bolle said. “But yes, it wears on you. It wears you down, and you feel isolated and you feel left out.” About 48% of Minnesotans feel left out some of the time or often, according to the “Minds of Minnesotans” survey conducted by APM Research Lab. The poll also finds that about half of Minnesotans feel lonely, at least some of the time. More specifically, 13% say they “often” lack companionship and another 35% lack companionship “some of the time.” Results were similar when Minnesotans were asked how often they feel left out and isolated from others. Bolle was one of 3,399 participants surveyed by the firm Lumaris. He said he often feels a lack of companionship as well. He hasn’t been in a relationship since 2009. He often feels left out and sometimes feels isolated. “I’m isolated in the sense where I really can’t find a suitable partner,” he said. His social connections are at his nursing assistant job, which he looks forward to, Bolle said. He’s never thoroughly enjoyed a job as much as his role at a skilled nursing facility, he said. “Work is great. I get to see people, I get to interact with people. I get to chat and talk and all the things that you know, that people do,” Bolle said. “That’s really hard to find.” The loneliness epidemic The APM Research Lab included these questions in the survey, conducted this year between July 20 and Nov. 22, to better understand what the U.S. Surgeon General has called “Our Epidemic of Loneliness and Isolation.” The three questions used in the APM Research Lab survey were replicated from the widely used UCLA Loneliness Scale to help assess Minnesotans’ state of mind in the post-pandemic era, and possibly to help identify groups of Minnesotans that are faring better or worse with feelings of loneliness and isolation. In 2023, U.S. Surgeon General Dr. Vivek Murthy issued a report calling loneliness an epidemic, posing significant health risks akin to tobacco usage, obesity and addiction. Loneliness intersects with various aspects of people’s lives, said Carrie Henning-Smith, an associate professor in the Division of Health Policy and Management at the University of Minnesota School of Public Health. “Social isolation and loneliness have profound impacts on health, on mortality risks, on all of the ways that our lives play out within health, within that sphere, but in so many other ways, too,” said Henning-Smith, who conducts research on rural populations as the co-director of the University of Minnesota Rural Health Research Center and the Rural Health Program. According to the U.S. Surgeon General report, “the physical health consequences of poor or insufficient connection include a 29 percent increased risk of heart disease, a 32 percent increased risk of stroke, and a 50 percent increased risk of developing dementia for older adults.” A lack of social connections increases the risk of premature death by more than 60%, the report added. Mary Jo Kreitzer, the founder and director of the Earl Bakken Center for Spirituality and Healing at the University of Minnesota, said the report is significant. “Just by him [Murthy] touching that subject, everybody remembers that he did,” she said. “People remembered that. Because I’m sure that everybody has somebody like that in their life, or they themselves are feeling lonely.” There’s also a stigma surrounding the idea of loneliness. “People are reluctant to admit that they feel lonely. It somehow means like that you’re unlikable or unlovable or there’s something wrong with you,” Henning-Smith said. “It’s important to have these conversations, because the truth is, just about everyone will feel lonely at some point in their life.” she added. “It's a universal part of being human.” Kreitzer said the data reported by APM Lab is comparable to other global and U.S. data on the subject. “Other studies, like this one found that loneliness peaks in younger age groups,” she said, calling it “a very interesting finding.” The survey found that the Gen Z cohort of 18 to 27, were the most lonely. “That surprises a lot of people, but I think it’s consistent with other data,” Kreitzer said. She said people assume that older people suffer from loneliness because they lack the social connections they once had earlier in their lives. The survey data, instead, showed that baby boomers, currently aged 60-78, are the least lonely of adult-age generations in Minnesota: 63% score as “rarely lonely” and only 7% indicated frequent loneliness. “Sometimes, like in the boomer generation, when people have retired, they actually have more time to build and strengthen connections,” Kreitzer said. “Boomers can be great at joining groups, pursuing interests, be that hobbies or fitness activities or book clubs or volunteering, and all of those are ways that can really help us build social connections.” She said her local YMCA in Grand Rapids is a hub of activity with engaged older folks. She sees them playing cards, working out, swimming and more. Gen Zers, however, are experiencing numerous life transitions. “During that age, they’re expected to separate from their family, to find a partner, to launch a career,” Kreitzer said. “So there’s been a lot of disruption in social connections that they probably have had in their life for a long, long time.” Henning-Smith called the loneliness rates among young adults “concerning.” Social media and technology may explain part of the higher rates. “People who live their lives online, people who are digital natives and were born into a world where they’re living their lives online, have fundamentally different ways of connecting with other people,” Henning-Smith said. “I worry that some of those skills and some of the infrastructure for connecting with people in meaningful ways and in-person connections might be lacking for some folks in younger generations.” Kreitzer suggests to those who may have frequent bouts of loneliness to acknowledge the feelings. Don’t ignore them. She advises them to reach out to family and friends to try to build or rebuild social connections. She also encourages people to join groups based on their interests. Kreitzer highly recommends volunteering because of the health benefits associated with it. “There’s actually research on that that, like, volunteering helps improve our own well-being,” she said. “It can actually improve our overall positive outlook, our mental health and well-being.” Rugged yet lonely individuals Back in Hayfield, Bolle said he tries to find community to fend off his loneliness. His location is a challenge because he finds groups in the Twin Cities some 90 miles away. He belongs to a spiritual group that meets once a week in Rochester, but that’s a 52-mile round trip, so he only goes from time to time. Bolle also prepares himself to encounter situations that bring on feelings of loneliness when he goes to Rochester on his weekends to run errands. “When I see families out having fun together, or groups of people, groups of young people, you know, out together and having fun, that can trigger pangs of loneliness,” he said. “I just feel like I’m missing out on human connection.” He said when he was younger, he bought into society’s emphasis on rugged individualism. “But it just doesn’t work, because you will almost ultimately, always end up feeling lonely,” he said. When he traveled the world with the Navy, Bolle said he saw community and family as top priorities in other countries as well as in the Mexican and Latino communities of Southern California where he grew up. “You really do need that connection with other people,” he said. “It’s almost as important as food and shelter, you know?” The data and the heart appear to agree. This story was originally published on MPRNews.org
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ACD urges union, US Gulf, East Coast ports to delay deadline for contract agreementHONOLULU (AP) — Michael Rataj had 16 points in Oregon State's 74-65 win over Charleston at the Diamond Head Classic on Sunday. Rataj also had 12 rebounds for the Beavers (9-2). Damarco Minor also scored 16 points, going 5 of 11 from the floor, including 2 for 5 from 3-point range, and 4 for 4 from the line. Parsa Fallah shot 6 of 7 from the field and 2 for 3 from the line to finish with 14 points. The Cougars (8-3) were led by Lazar Djokovic, who recorded 13 points, eight rebounds and two steals. Derrin Boyd added 13 points for Charleston. Deywilk Tavarez also had 10 points. Oregon State took the lead with 15:29 to go in the first half and never looked back. The score was 35-26 at halftime, with Fallah racking up 13 points. Oregon State closed out the victory in the final half, while Minor led the way with a team-high 14 second-half points. ___ The Associated Press created this story using technology provided by and data from . The Associated PressSouth Korea martial law: Canada, other countries urge caution to travellers
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GCC Sustainability Innovation Hub Releases Landmark White Paper On Achieving Net-Zero Emissions In Telecom SectorShare Tweet Share Share Email Mumbai, February 28, 2025 – A Date to Remember for Cybersecurity Enthusiasts Mark your calendars and get ready for the most awaited cybersecurity gathering of the year— TotalSecure Conclave & Awards 2025. This transformative event will take place at the prestigious Holiday Inn Mumbai International Airport, uniting the brightest minds from Cyber, Cloud, and Network Security to address the evolving challenges shaping our digital landscape. “Safeguarding the Future Against Evolving Threats” is the event’s theme, setting the tone for an immersive and action-packed day. Attendees can look forward to thought-provoking keynotes, engaging panel discussions, cutting-edge partner showcases, and a prestigious awards ceremony recognizing excellence in cybersecurity. Why You Should Attend Stay Ahead of Emerging Threats: Learn about the latest trends, technologies, and strategies to navigate and counter today’s sophisticated cybersecurity challenges. Connect with Industry Leaders: Meet the trailblazers, innovators, and decision-makers shaping the future of cybersecurity, cloud, and network security. Discover Cutting-Edge Innovations: Explore groundbreaking tools and solutions to strengthen your organization’s security posture. Actionable Insights: Gain practical strategies and insights from industry experts that you can immediately apply to fortify your defenses. Celebrate Excellence: Be part of the prestigious TotalSecure Awards, honoring organizations and individuals making significant contributions to the cybersecurity domain. Whether you’re a seasoned professional or an emerging leader, this event promises an unparalleled opportunity to stay ahead of the curve and prepare for a secure future. What’s in Store for Attendees? Insightful Keynotes & Panels: Delve into pivotal topics like AI in cybersecurity, unified defense strategies, and future trends in network security. Dynamic Networking Opportunities: Engage with industry peers, policymakers, and visionaries to share ideas, challenges, and solutions. Innovative Technology Showcases: Get hands-on exposure to cutting-edge tools and technologies designed to mitigate emerging threats and drive operational resilience. Recognition of Excellence: Witness the achievements of cybersecurity pioneers as they are celebrated during the awards ceremony. Who Should Attend? The event is designed for a diverse audience of professionals, ensuring every attendee finds value in the discussions and networking opportunities. Key participants include: Chief Information Security Officers (CISOs) Chief Technology Officers (CTOs) Chief Information Officers (CIOs) Cybersecurity Directors and Managers Cloud Security Architects Network Security Managers Risk Management Professionals Compliance Officers AI and Machine Learning Security Specialists Governance, Risk, and Compliance (GRC) Professionals Forensics and Threat Intelligence Experts Key Highlights of the Agenda Convergence of Cyber, Cloud, and Network Security: Building unified defense strategies to combat evolving threats. Cybersecurity Trends 2025: Analyzing the trends, opportunities, and challenges shaping the future. The Dual Role of AI: Exploring how artificial intelligence acts both as a defense mechanism and a tool for attackers. Future of Network Security: Insights and predictions for 2025 and beyond. Event Details Date: February 28, 2025 Venue: Holiday Inn Mumbai International Airport Website: www.totalsecureconclave.com Contact: akjaiswal@ibiind.com | +91 9819020274 Secure Your Spot Today! Don’t miss this unparalleled opportunity to enhance your knowledge, connect with thought leaders, and discover solutions that will empower you to stay ahead in the cybersecurity domain. With a powerful agenda, a distinguished audience, and a focus on actionable insights, the TotalSecure Conclave & Awards 2025 is the ultimate event for professionals committed to securing the future of digital landscapes. Join us on February 28, 2025, for an inspiring day of learning, networking, and celebration. Let’s shape the future of cybersecurity together! Related Items: cybersecurity , TotalSecure Conclave and Awards 2025 Share Tweet Share Share Email Recommended for you Yuwei Xiao: The “Supergirl” in the Cybersecurity Realm Advanced Data Reconciliation Techniques With Industry Leader Praveen Tripathi, Revolutionizing Data Integrity And Scalability. Securing the Future of AI: Insights from Cybersecurity Specialist Alok Jain. CommentsBEREA, Ohio -- The Cleveland Browns have again restructured quarterback Deshaun Watson's massive contract to create salary-cap space and give them future flexibility, a person familiar with the move told The Associated Press on Friday. Watson has been limited to just 19 games in three seasons because of an NFL suspension and injuries with the Browns, who signed him to a five-year, $230 million fully guaranteed contract in 2022. The restructuring allows the team to spread out the salary-cap hit after the 2026 season, said the person, who spoke on condition of anonymity because the team does not disclose contract specifics. The 29-year-old Watson has two years remaining on his contract with an average of $46 million a year, and with a salary-cap hit of $72.9 million in those seasons. The latest move adds a voidable year for 2028, giving the Browns cap flexibility following 2026, the final year on Watson’s deal. The agreement to restructure Watson's contract will not preclude the Browns from adding talent at the quarterback position in 2025, the person said. Watson played in only seven games this season before suffering a ruptured Achilles tendon. He's 9-10 as a starter with Cleveland. The Browns (3-12) have been a major disappointment after making it to the playoffs a year ago behind Joe Flacco, who was signed as a free agent after Watson suffered a season-ending shoulder injury. Watson had surgery in October and is expected to make a full recovery. While the team hasn't disclosed its plans at quarterback, it's assumed Watson will be in the mix to be the starter next season. It's also possible the Browns will draft a quarterback in the first round. The team hasn't had a first-round pick the past three years after trading three to the Houston Texans to acquire Watson, who was once considered one of the league's elite QBs. Watson's disappointing tenure — he hasn't thrown for 300 yards in any game — has been a sore spot with Cleveland fans, who had hoped the team had finally resolved its interminable QB issues when they signed the three-time Pro Bowler three years ago. But it hasn't worked out, and the major investment in Watson and the salary-cap ramifications of his contract — the largest fully guaranteed deal in league history — have made it difficult for the Browns to upgrade their roster. Watson has shown flashes of being a competent starting quarterback, but there have been just as many moments in which he's looked hesitant in the pocket or unable to connect with receivers down field. Watson was suspended for the first 11 games of his first season in Cleveland after an independent arbiter ruled he violated the conduct policy after he was accused by more than two dozen women of sexual misconduct during massage therapy sessions. Since having surgery, Watson has been rehabbing his Achilles injury. He has not spoken to reporters for months. On Thursday, he posted a photo of himself on Instagram standing without wearing a walking boot. The caption read: “Back on My Feet! MOREGLORY!” Last week, Browns defensive star Myles Garrett caused a stir by saying he did not want to be part of a rebuild in Cleveland. Garrett also made it clear he wanted to know the team's offseason plans, including what the Browns intended to do at quarterback. On Friday, Garrett said he had “a few” discussions this week with the team's front office following his surprising comments. The reigning Defensive Player of the Year didn't reveal any specifics of the talks. “They just wanted to see where my head was at and what I was thinking and just trying to keep things in house, in house,” said Garrett, who will turn 29 on Sunday. Garrett was asked if he got a favorable reaction from teammates. “They want to know what’s coming next as well,” he said. “So I haven’t really heard too many people speak up on whether they liked my comments or not. Everyone’s kind of feeling the same way. But I’m not going to assume and I’ll have my answer at the end of the year.” NOTES: TE David Njoku (knee), DE Ogbo Okoronkwo (knee) and WR Cedric Tillman (concussion) were ruled out for Sunday's game. ... Backup QB Jameis Winston (shoulder) is questionable. If he can't play, Bailey Zappe will be Cleveland's No. 2 QB behind Dorian Thompson-Robinson. ... Coach Jason Tarver said LB Jeremiah Owusu-Koramoah is in “good spirits” after sustaining a neck injury on Oct. 27. Owusu-Koramoah was hurt in a collision with Ravens running back Derrick Henry. The Browns have been vague about Owusu-Koramoah's injury and recovery. ___ AP NFL: https://apnews.com/hub/NFL
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