Closing marks second significant acquisition from RA Capital's Raven incubator in 2024, and first acquisition of a company built by Raven from a technology platform in-licensed from a large pharmaceutical company BOSTON , Dec. 11, 2024 /PRNewswire/ -- RA Capital Management, LP (RA Capital), a multi-stage investment manager dedicated to evidence-based investing in public and private healthcare, life sciences, and planetary health companies, today announced that AbbVie has closed its $1.4 billion acquisition of RA Capital's portfolio company Aliada Therapeutics. Aliada's lead investigational asset is ALIA-1758, an anti-pyroglutamate amyloid beta (3pE-Aβ) antibody, which is in development for the treatment of Alzheimer's disease and is currently in a Phase 1 clinical trial. ALIA-1758 utilizes a novel blood-brain barrier-crossing technology that enhances delivery of targeted drugs into the central nervous system. Johnson & Johnson (through its venture capital arm, Johnson & Johnson Innovation – JJDC, Inc.), RA Capital, and Raven (RA Capital's healthcare incubator) co-founded Aliada and co-led the series seed financing in 2021 to advance the MODELTM platform created by Johnson & Johnson scientists that was licensed to Aliada at its inception. "Congratulations to the Aliada and AbbVie teams and our fellow investors on the close of this transaction," said Joshua Resnick , MD, Senior Managing Director at RA Capital Management and former board director at Aliada. "The acquisition of Aliada is the second significant acquisition of a Raven-grown company this year, joining Novartis' $1 billion upfront acquisition of radiopharmaceutical developer Mariana Oncology in May." "Delivering therapeutics across the blood-brain barrier with a low-volume, subcutaneous injection would be revolutionary for treating Alzheimer's disease and other neurological disorders, and has long been a dream in the field," said Laura Tadvalkar , PhD, Managing Director at RA Capital Management and former board chair at Aliada. "We look forward to following ALIA-1758's progress through the clinic, as AbbVie advances this important medicine for Alzheimer's disease patients." About Raven Raven is RA Capital Management's healthcare incubator. Raven's experienced team of scientists, operators, and innovators bring deep sector expertise, insight and executional capabilities across therapeutics, diagnostics, devices, and services. Raven builds companies: from originating and incubating new ideas to accelerating compelling innovations and rejuvenating promising assets. About RA Capital Founded in 2004, RA Capital Management is a multi-stage investment manager dedicated to evidence-based investing in public and private healthcare, life sciences, and planetary health companies. RA Capital creates and funds innovative companies, from private seed rounds to public follow-on financings, allowing management teams to drive value creation from inception through commercialization and beyond. RA Capital's knowledge engine is guided by our TechAtlas internal research division, and Raven, RA Capital's company creation team, offers entrepreneurs and innovators a collaborative and comprehensive platform to explore the novel and the re-imagined. RA Capital has more than 175 employees and over $10 billion in assets under management. The companies presented herein were selected to demonstrate a potential successful outcome of a company being incubated within our Raven incubator. They are not intended to represent a complete picture of RA Capital's portfolio, its exposures, risks or potential for positive or negative returns. Past performance is not indicative of future results. View original content to download multimedia: https://www.prnewswire.com/news-releases/ra-capital-management-announces-close-of-1-4-billion-acquisition-of-aliada-therapeutics-by-abbvie-302329567.html SOURCE RA Capital Management, LPKorean bond market at crossroads ahead of 2025 supplementary budget
OpenAI's For-Profit Transition, Trump's AI Advisor, And Google's Code Red: This Week In AIFinancial giants have made a conspicuous bullish move on Alphabet. Our analysis of options history for Alphabet GOOGL revealed 45 unusual trades. Delving into the details, we found 55% of traders were bullish, while 33% showed bearish tendencies. Out of all the trades we spotted, 15 were puts, with a value of $1,256,958, and 30 were calls, valued at $1,436,733. Expected Price Movements After evaluating the trading volumes and Open Interest, it's evident that the major market movers are focusing on a price band between $110.0 and $300.0 for Alphabet, spanning the last three months. Volume & Open Interest Development Assessing the volume and open interest is a strategic step in options trading. These metrics shed light on the liquidity and investor interest in Alphabet's options at specified strike prices. The forthcoming data visualizes the fluctuation in volume and open interest for both calls and puts, linked to Alphabet's substantial trades, within a strike price spectrum from $110.0 to $300.0 over the preceding 30 days. Alphabet Call and Put Volume: 30-Day Overview Noteworthy Options Activity: Symbol PUT/CALL Trade Type Sentiment Exp. Date Ask Bid Price Strike Price Total Trade Price Open Interest Volume GOOGL PUT TRADE BULLISH 12/19/25 $4.85 $4.7 $4.7 $130.00 $305.5K 591 662 GOOGL PUT TRADE BEARISH 06/20/25 $24.0 $23.95 $24.0 $185.00 $144.0K 1.0K 60 GOOGL CALL TRADE BEARISH 06/20/25 $41.9 $41.85 $41.85 $130.00 $125.5K 1.1K 30 GOOGL PUT SWEEP BULLISH 04/17/25 $8.0 $7.9 $7.9 $160.00 $115.3K 3.3K 318 GOOGL CALL TRADE BULLISH 01/16/26 $10.85 $10.85 $10.85 $200.00 $108.5K 4.3K 431 About Alphabet Alphabet is a holding company that wholly owns internet giant Google. The California-based company derives slightly less than 90% of its revenue from Google services, the vast majority of which is advertising sales. Alongside online ads, Google services houses sales stemming from Google's subscription services (YouTube TV, YouTube Music among others), platforms (sales and in-app purchases on Play Store), and devices (Chromebooks, Pixel smartphones, and smart home products such as Chromecast). Google's cloud computing platform, or GCP, accounts for roughly 10% of Alphabet's revenue with the firm's investments in up-and-coming technologies such as self-driving cars (Waymo), health (Verily), and internet access (Google Fiber) making up the rest. After a thorough review of the options trading surrounding Alphabet, we move to examine the company in more detail. This includes an assessment of its current market status and performance. Present Market Standing of Alphabet With a volume of 23,824,736, the price of GOOGL is down -1.64% at $164.88. RSI indicators hint that the underlying stock is currently neutral between overbought and oversold. Next earnings are expected to be released in 67 days. What The Experts Say On Alphabet Over the past month, 5 industry analysts have shared their insights on this stock, proposing an average target price of $202.8. Turn $1000 into $1270 in just 20 days? 20-year pro options trader reveals his one-line chart technique that shows when to buy and sell. Copy his trades, which have had averaged a 27% profit every 20 days. Click here for access .* Consistent in their evaluation, an analyst from Loop Capital keeps a Hold rating on Alphabet with a target price of $185. * An analyst from Wells Fargo persists with their Equal-Weight rating on Alphabet, maintaining a target price of $187. * Maintaining their stance, an analyst from Keybanc continues to hold a Overweight rating for Alphabet, targeting a price of $215. * An analyst from B of A Securities has decided to maintain their Buy rating on Alphabet, which currently sits at a price target of $210. * Reflecting concerns, an analyst from BMO Capital lowers its rating to Outperform with a new price target of $217. Options are a riskier asset compared to just trading the stock, but they have higher profit potential. Serious options traders manage this risk by educating themselves daily, scaling in and out of trades, following more than one indicator, and following the markets closely. If you want to stay updated on the latest options trades for Alphabet, Benzinga Pro gives you real-time options trades alerts. © 2024 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.Health authorities in the United Kingdom have warned the public against cheap Brazilian butt lift (BBL) from overseas clinics. The invasive cosmetic procedure is being offered abroad for under £3,000, inclusive of hotel accommodation and flight fare, to entice customers. In contrast, local BBL costs 70 percent higher in the United Kingdom, according to the National Health Service (NHS). However, a spate of deaths and medical complications arising from botched BBL surgeries, with the NHS frequently having to treat patients when they return home, prompted the warning posted on the NHS website on 21 December. In the post, NHS National Medical Director Professor Sir Stephen Powis also said BBL surgery has the highest death rate of all cosmetic procedures as the fat injected into the buttocks can lead to a pulmonary embolism, which is a blockage in a blood vessel in the lungs that can be fatal. “While many people’s social media feeds will be full of enticing looking offers in the run up to Christmas, the reality is these bargain basement cosmetic procedures are potentially deadly,” he warned. Meanwhile, a literal case of butt lifting has been remedied using 3-D printing technology. Mystic Aquarium senior veterinarian Dr. Molly Martony revealed that the company Adia measured and scanned Charlotte for the design of a customized prosthetic harness to remedy a “bubble butt syndrome” (BBS). Charlotte, a green sea turtle at the Connecticut aquarium, is suffering from BBS years after it was hit by a boat that damaged her shell and spinal cord. The BBS caused the male green sea turtle to be buoyant and vertical in the water because air in its gastro-intestinal tract lifts its butt up. The position can damage its organs, Claire Bolster, Charlotte’s handler, said, according to ABC News. With the prosthetic harness fitted on Charlotte’s shell, weights can be placed to pull his butt down and let him swim at level and more smoothly.
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Coldplay kick England out of Wembley: FA are left searching for new venue with British band playing sold out shows during September fixtures... with viral video showing huge toll of transforming arena into football pitch England discovered their 2026 World Cup qualifying opponents on Friday Three Lions will have to make arrangements for home fixture against Andorra LISTEN NOW: It's All Kicking Off! Mason Mount? Marcus Rashford? Joshua Zirkzee? Who should Manchester United sell to raise funds? By TUM BALOGUN Published: 23:04 GMT, 13 December 2024 | Updated: 23:26 GMT, 13 December 2024 e-mail View comments Thomas Tuchel 's England will have to make alternative arrangements for their World Cup qualifier against Andorra next September. The German's first opponents as Three Lions boss were revealed on Friday as the draw for the qualification stage of the 2026 World Cup was conducted in Zurich. Tuchel, who officially begins duties on January 1, will get his first taste of action during the March international break with games against Albania and Latvia. Those games will also see the former Chelsea manager lead his side out at Wembley, a privilege that is set to be denied for England's September international against Andorra because of clash with Coldplay . The British band were only due to play at the home of football for six nights in August but, due to unprecedented demand, they added four more dates in September, which fall on either side of England's fixture. Although the Viva La Vida group are not due to perform on September 6 when Tuchel's troops will be lining up against the European minnows, the extraordinary retrofit undertaken to turn a football stadium into the perfect space for a concert would make staging the game there impossible. As a result, Harry Kane and Co will be playing a little further away from home than first planned. Coldplay have scheduled a series of sold out shows at Wembley stadium in August and September The British ban will play at the home of football on 10 nights and they will transform the famous old ground to suit their performance @superconstructions #coldplay #concert #setup #installation #construction #civilengineering #constructiontips #constructionlife #building #timelapse #replacement #reconstruction #coldplay ♬ House - ruanoliivas Thomas Tuchel will begin duties as England manager on January 1, while his first match as boss will be against Albania in March The news is sure to delight many fans across the country who will now find it easier to watch their England heroes up close. The FA has made strides in recent years to stage Three Lions fixtures outside of London. The likes of Old Trafford, The Stadium of Light and St James' Park have all hosted home games in recent seasons. In addition to Albania, Latvia and Andorra, Tuchel's side were also drawn against Serbian in Group K. Following the draw, Tuchel admitted that he was aware of the mixed reaction to his appointment but he insisted he is ready prove his doubters wrong. ‘I read much less than you would expect,’ Tuchel said. ‘Maybe you can tell me how it was received. But no hard feelings for that. Of course, it will always be mixed. ‘So now I have to prove myself. And to the people who are maybe a bit concerned - to prove to them how much it means to me and that it's a dream job for me that I will give my everything, and I'm the man for the job.’ Serbia are the highest ranked of England’s opponents at number 32 on the FIFA list. England have only played them once, winning 1-0 through a Jude Bellingham goal in the opening game of last summer’s Euros. That apart England will not have reason to particularly fear Albania – who they have beaten four times from four games – or Latvia – who they have never played – and Andorra, against whom they have accumulated a 26-0 aggregate score over six matches. Latvia Share or comment on this article: Coldplay kick England out of Wembley: FA are left searching for new venue with British band playing sold out shows during September fixtures... with viral video showing huge toll of transforming arena into football pitch e-mail Add comment
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