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-3810109 is an antibody commercialized by , with a leading Phase II program in Human Immunodeficiency Virus (HIV) Infections (AIDS). According to Globaldata, it is involved in 4 clinical trials, of which 3 were completed, and 1 is ongoing. Smarter leaders trust GlobalData The gold standard of business intelligence. The revenue for -3810109 is expected to reach an annual total of $132 mn by 2038 in the US based off GlobalData’s Expiry Model. The drug’s revenue forecasts along with estimated costs are used to measure the value of an investment opportunity in that drug, otherwise known as net present value (NPV). Applying the drug’s phase transition success rate to remaining R&D costs and likelihood of approval (LoA) to sales related costs provides a risk-adjusted NPV model (rNPV). The rNPV model is a more conservative valuation measure that accounts for the risk of a drug in clinical development failing to progress. GSK-3810109 Overview -3810109 is under development for the treatment of human immunodeficiency virus (HIV) infections. The drug candidate is a broadly neutralizing antibody acts by targeting gp120. It is administered through intravenous or subcutaneous route. GSK Overview is a healthcare company that focuses on developing, manufacturing and commercializing general medicines, specialty medicines and vaccines. It offers drugs for the treatment of diseases such as HIV, respiratory, cancer, immuno-inflammation, anti-viral, central nervous system (CNS), metabolic, cardiovascular, and urogenital, anti-bacterial, dermatology and rare diseases. The company also offers over-the-counter (OTC) products for pain relief, oral health, nutrition, skin health and gastrointestinal diseases. ’s vaccine portfolio covers various diseases including hepatitis, diphtheria, tetanus, whooping cough, rotavirus and HPV infections, measles and bacterial meningitis, among others. The company sells its products through wholesalers, pharmacies, hospitals, physicians and other groups worldwide. is headquartered in Brentford, Middlesex, the UK. The company reported revenues of (British Pounds) GBP30,328 million for the fiscal year ended December 2023 (FY2023), an increase of 3.4% over FY2022. In FY2023, the company’s operating margin was 22.2%, compared to an operating margin of 21.9% in FY2022. In FY2023, the company recorded a net margin of 16.2%, compared to a net margin of 51% in FY2022. The company reported revenues of GBP7,884 million for the second quarter ended June 2024, an increase of 7.1% over the previous quarter. For a complete picture of -3810109’s valuation, From Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors. , the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article. To create this model, GlobalData takes into account factors including patent law, known and projected regulatory approval processes, cash flows, drug margins and company expenses. Combining these data points with GlobalData’s world class analysis creates high value models that companies can use to help in evaluation processes for each drug or company. The rNPV method integrates the probability of a drug reaching a clinical stage into the cash flow at that time, which provides a more accurate valuation, as it considers the probability that the drug never makes it through the clinical pathway to commercialization. GlobalData’s rNPV model uses proprietary likelihood of approval (LoA) and phase transition success rate (PTSR) data for the indication in the highest development stage, which can be found on GlobalData’s .300 sign up bonus casino philippines real money



, /PRNewswire/ -- Representatives from and shared their insights on promoting artificial intelligence (AI) governance and data sharing at a sub-forum of the 20th Beijing-Tokyo Forum in recently. The sub-forum contributed eastern wisdom to AI governance and digital social development, demonstrating the significance of international cooperation for the development of the digital economy, according to Gao Shaolin, advisor at Peking University's Legal Artificial Intelligence Research Center. AI governance framework The participants agreed that the next 10 years will be a critical period for the development of AI. Gao Wen, academician of the Chinese Academy of Engineering (CAE), said since State Council issued a guideline on developing AI in 2017, the nation has made significant progress in AI research and development and industrial layout, especially in computing power and 5G network construction. By the end of 2023, had over half of the world's 1.57 billion 5G users, according to the World Internet Development Report 2024. It ranked second globally in AI and computing power scale, which has laid a solid foundation for the rapid development of AI. , project professor at the of Health and Welfare, said it was very meaningful for and to discuss strengthening AI governance rules. , research director of the Nomura Research Institute, echoed his view. He emphasized that the core goal of AI technology is to improve productivity and eliminate obstacles to social development, and called on Chinese and Japanese experts to work together to build an AI governance framework to cope with the global challenges. Deepening international cooperation put forth the Global AI Governance Initiative in October last year. In July, the UN General Assembly adopted a -sponsored resolution on enhancing international cooperation on AI capacity-building. The participants spoke highly of the Global Cross-Border Data Flow Cooperation Initiative recently proposed by . They agreed that AI governance requires global collaboration, especially in the formulation of international standards and the construction of ethical frameworks, where and can play an active role. Ding Wenhua, academician of the CAE, said and have both similarities and differences in technology development and governance priorities, so deepening cooperation will bring unique value to global AI governance. " and should deepen AI technology cooperation between enterprises, work together in AI security research, talent exchange, and jointly explore more possibilities for the application of technology," , president of the Beijing Academy of Artificial Intelligence, said. Balancing development & risks AI governance refers to the guardrails established to ensure AI systems and tools remain safe and ethical and respect human rights. , editor-in-chief of Science and Technology Daily, stressed that AI, as a revolutionary technology, has far-reaching impacts on all areas of society and economy. However, its potential risks such as data leakage and the spread of false information should not be ignored. "Technological progress and security ethics should be developed in a balanced way to ensure that AI technology always serves the progress of human civilization," Xu said. AI governance should not only heed the current technological ethics issues, but also prevent possible long-term risks, such as AI going out of human control, according to , senior corporate advisor of NTT DATA. He said AI R&D and application should abide by the principles of fairness, transparency, safety and availability. Yuan Yue, chairman of Beijing Dataway Horizon, shared his view from the perspective of regulatory models. "Policy choices should be based on the current status and goals of national technological development," Yuan said, adding that prefers to provide a more friendly development environment for enterprises while ensuring an effective response to risks. View original content to download multimedia: SOURCE Science and Technology DailyNFL punishes Denver Broncos star defender ahead of Week 12 divisional matchup vs. Las Vegas Raiders

After weeks of fear and bewilderment about the drones buzzing over parts of New York and New Jersey , U.S. Senator Chuck Schumer is urging the federal government to deploy better drone-tracking technology to identify and ultimately stop the airborne pests. The New York Democrat is calling on the Department of Homeland Security to immediately deploy special technology that identifies and tracks drones back to their landing spots, according to briefings from his office. Javascript is required for you to be able to read premium content. Please enable it in your browser settings. Success! An email has been sent to with a link to confirm list signup. Error! There was an error processing your request. Get the latest need-to-know information delivered to your inbox as it happens. Our flagship newsletter. Get our front page stories each morning as well as the latest updates each afternoon during the week + more in-depth weekend editions on Saturdays & Sundays.

Donald Trump is going to return to the White House in style, after having secured a massive win in the US Presidential elections 2024, by beating Kamala Harris. A gala inauguration ceremony at the US Capitol, Washington DC has been arranged for the President-elect's swearing-in, after which he will be taking over the reigns of Presidency from Joe Biden. ET Year-end Special Reads Corporate Kalesh: Top family disputes of India Inc in 2024 The world of business lost these eminent people in 2024 Fast, faster, fastest: How 2024 put more speed into your shopping Billionaires and their companies line up to donate for Trump Meanwhile, there is a lot of ruckus among top-notch companies, especially those based in Silicon Valley, about donating in Donald Trump's inauguration ceremony. The likes of Mark Zuckerberg, Jeff Bezos, and many others have donated in millions for this gala inauguration ceremony, with many other companies waiting in line to bring in funds for this prestigious event. But, the question arises: Why this sudden pandemonium regarding donating towards Trump's ceremony? Are companies expecting relaxations from the Trump administration? Reports suggest that it could be because the companies are hoping for a business-friendly behavior from the Trump administration, and executive powers are not used to cripple any company. Trump, on numerous occasion before becoming the President-elect has threated top companies with different statements on what he would do if he comes to power, and when that has become a reality, companies may be fearing what's going to happen next. These donations are majorly being seen as a gesture and effort by companies to keep Trump appeased. A Rolling Stone report also suggests that his people may be keeping a close track on who is spending what on the inauguration ceremony, in order to monitor the chunk of cash flowing in for this prestigious event. FAQs: Is Donald Trump the reigning US President? No, as of now, Joe Biden is the reigning US President, but Trump will be taking over the reigns soon, after the gala inauguration ceremony on January 20 next year. 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West Palm Beach (FL), Dec 1 (AP) Canadian Prime Minister Justin Trudeau returned home Saturday after his meeting with Donald Trump without assurances the president-elect will back away from threatened tariffs on all products from the major American trading partner. Trump called the talks "productive" but signalled no retreat from a pledge that Canada says unfairly lumps it in with Mexico over the flow of drugs and migrants into the United States. After the leaders' hastily arranged dinner Friday night at Trump's Mar-a-Lago club in Florida, Trudeau spoke of "an excellent conversation." Trump said in a Truth Social post later Saturday that they discussed "many important topics that will require both Countries to work together to address." For issues in need of such cooperation, Trump cited fentanyl and the "Drug Crisis that has decimated so many lives as a result of Illegal Immigration," fair trade deals "that do not jeopardize American Workers" and the US trade deficit with its ally to the north. Trump asserted that the prime minister had made "a commitment to work with us to end this terrible devastation" of American families from fentanyl from China reaching the United States through its neighbours. The US, he said, "will no longer sit idly by as our Citizens become victims to the scourge of this Drug Epidemic." The Republican president-elect has threatened to impose a 25 per cent tax on all products entering the US from Canada and Mexico as one of his first executive orders when he takes office in January. US customs agents seized 43 pounds of fentanyl at the Canadian border last fiscal year, compared with 21,100 pounds at the Mexican border. On immigration, the US Border Patrol made 56,530 arrests at the Mexican border in October alone and 23,721 arrests at the Canadian border between October 2023 and September 2024 — and Canadian officials say they are ready to make new investments in border security. Trudeau called Trump after the Republican's social media posts about the tariffs last Monday and they agreed to meet, according to a official familiar with the matter who was not authorised to publicly discuss detail of the private talks. The official said other countries are calling Canadian officials to hear how about how the meeting was arranged and to ask for advice. Mexican President Claudia Sheinbaum, after speaking with Trump on the telephone, said Thursday she was confident a tariff war with Washington would be averted. At the dinner that was said to last three hours, Trump said he and Trudeau also discussed energy, trade and the Arctic. A second official cited defence, Ukraine, NATO, China, the Mideast, pipelines and the Group of Seven meeting in Canada next year as other issues that arose. Trudeau's office said in a statement that the leaders "shared a productive wide-ranging discussion" centring on "collaboration and strengthening our relationship," adding, "As Canada's closest friend and ally, the United States is our key partner, and we are committed to working together in the interests of Canadians and Americans.” Trump, during his first term as president, once called Trudeau "weak" and "dishonest," but it was the prime minister who was the first G7 leader to visit Trump since the Nov. 5 election. "Tariffs are a crucial issue for Canada and a bold move was in order. Perhaps it was a risk, but a risk worth taking," Daniel Béland, a political science professor at McGill University in Montreal. Trudeau had said before leaving from Friday that Trump was elected because he promised to bring down the cost of groceries but now was talking about adding 25 per cent to the cost of all kinds of products, including potatoes from Prince Edward Island in Atlantic Canada. "It is important to understand that Donald Trump, when he makes statements like that, he plans on carrying them out. There's no question about it," Trudeau said. "Our responsibility is to point out that he would not just be harming Canadians, who work so well with the United States, but he would actually be raising prices for Americans citizens as well and hurting American industry and business," he added. The threatened tariffs could essentially blow up the North American trade pact that Trump's team negotiated during his first term. Trudeau noted they were able to successfully renegotiate the deal, which he calls a "win win" for both countries. When Trump imposed higher tariffs as president, other countries responded with retaliatory tariffs of their own. Canada, for instance, announced billions of new duties in 2018 against the US in a response to new taxes on Canadian steel and aluminum. Canada is the top export destination for 36 US states. Nearly $3.6 billion Canadian (US $2.7 billion) worth of goods and services cross the border each day. About 60 per cent of US crude oil imports are from Canada, and 85 per cent of US electricity imports are from Canada. Canada is also the largest foreign supplier of steel, aluminum and uranium to the US and has 34 critical minerals and metals that the Pentagon is eager for and investing in for national security. Canada is one of the most trade-dependent countries in the world, and 77 per cent of Canada's exports go to the US. (AP) VN VN (This story has not been edited by THE WEEK and is auto-generated from PTI)

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