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A novel strategy, recently detailed, promises to redefine investment paradigms with its forward-thinking approach. A Fresh Perspective on Investment Renowned for its financial expertise, The Motley Fool introduces a trailblazing investment strategy that steps away from traditions. This concept has piqued the interest of investors eager for diverse pathways to wealth accumulation. Unlike conventional methods focusing on well-established firms, this innovative approach stresses the significance of a diversified portfolio teeming with promising startups and budding businesses. How This Approach Stands Out The strategy pivots on an in-depth process intertwining market research with seasoned analysis. It’s not merely about selecting stocks; it captures a broader comprehension of current market dynamics, factoring in economic indicators and future potential. By encompassing emerging companies with significant growth prospects, investors could secure higher returns, albeit with heightened risks. Insights from Financial Experts Analysts at The Motley Fool highlight that, despite its inherent risks, this strategy harbors the potential for appreciable rewards. This necessitates a well-informed investor willing to adapt based on evolving market trends and metrics. Pros and Cons of Embracing the New Strategy Pros: – Higher Potential Returns: Engaging with upcoming enterprises offers the possibility of substantial gains. – Market Diversification: Increases portfolio diversity by branching into untapped sectors. – Growth Opportunities: Leverage the promising prospects of nascent companies. Cons: – Increased Risk: Emerging businesses can be unpredictable with higher chances of volatility. – Need for Vigilance: Continuous market monitoring and research are imperative. – Longer Payback Periods: May take time before significant returns manifest. Emerging Trends and Future Outlook Observers predict this strategy could usher in a paradigm shift as it aligns with ongoing trends favoring innovation. While rooted in risk, the potential for high-yield returns could entice risk-tolerant investors gear up for the impending changes. This transformative strategy demands a recalibration of traditional perspectives, urging investors to balance risk and reward thoughtfully. Could this be the key to navigating modern financial markets and securing a prosperous future?Noninvasive imaging method can penetrate deeper into living tissue December 11, 2024 Massachusetts Institute of Technology Researchers developed a non-invasive imaging technique that enables laser light to penetrate deeper into living tissue, capturing sharper images of cells. This could help clinical biologists study disease progression and develop new medicines. Facebook Twitter Pinterest LinkedIN Email Metabolic imaging is a noninvasive method that enables clinicians and scientists to study living cells using laser light, which can help them assess disease progression and treatment responses. But light scatters when it shines into biological tissue, limiting how deep it can penetrate and hampering the resolution of captured images. Now, MIT researchers have developed a new technique that more than doubles the usual depth limit of metabolic imaging. Their method also boosts imaging speeds, yielding richer and more detailed images. This new technique does not require tissue to be preprocessed, such as by cutting it or staining it with dyes. Instead, a specialized laser illuminates deep into the tissue, causing certain intrinsic molecules within the cells and tissues to emit light. This eliminates the need to alter the tissue, providing a more natural and accurate representation of its structure and function. The researchers achieved this by adaptively customizing the laser light for deep tissues. Using a recently developed fiber shaper -- a device they control by bending it -- they can tune the color and pulses of light to minimize scattering and maximize the signal as the light travels deeper into the tissue. This allows them to see much further into living tissue and capture clearer images. Greater penetration depth, faster speeds, and higher resolution make this method particularly well-suited for demanding imaging applications like cancer research, tissue engineering, drug discovery, and the study of immune responses. "This work shows a significant improvement in terms of depth penetration for label-free metabolic imaging. It opens new avenues for studying and exploring metabolic dynamics deep in living biosystems," says Sixian You, assistant professor in the Department of Electrical Engineering and Computer Science (EECS), a member of the Research Laboratory for Electronics, and senior author of a paper on this imaging technique. She is joined on the paper by lead author Kunzan Liu, an EECS graduate student; Tong Qiu, an MIT postdoc; Honghao Cao, an EECS graduate student; Fan Wang, professor of brain and cognitive sciences; Roger Kamm, the Cecil and Ida Green Distinguished Professor of Biological and Mechanical Engineering; Linda Griffith, the School of Engineering Professor of Teaching Innovation in the Department of Biological Engineering; and other MIT colleagues. The research will appear in Science Advances . Laser-focused This new method falls in the category of label-free imaging, which means tissue is not stained beforehand. Staining creates contrast that helps a clinical biologist see cell nuclei and proteins better. But staining typically requires the biologist to section and slice the sample, a process that often kills the tissue and makes it impossible to study dynamic processes in living cells. In label-free imaging techniques, researchers use lasers to illuminate specific molecules within cells, causing them to emit light of different colors that reveal various molecular contents and cellular structures. However, generating the ideal laser light with certain wavelengths and high-quality pulses for deep-tissue imaging has been challenging. The researchers developed a new approach to overcome this limitation. They use a multimode fiber, a type of optical fiber which can carry a significant amount of power, could couple it with a compact device called a "fiber shaper." This shaper allows them to precisely modulate the light propagation by adaptively changing the shape of the fiber. Bending the fiber changes the color and intensity of the laser. Building on prior work, the researchers adapted the first version of the fiber shaper for deeper multimodal metabolic imaging. "We want to channel all this energy into the colors we need with the pulse properties we require. This gives us higher generation efficiency and a clearer image, even deep within tissues," says Cao. Once they had built the controllable mechanism, they developed an imaging platform to leverage the powerful laser source to generate longer wavelengths of light, which are crucial for deeper penetration into biological tissues. "We believe this technology has the potential to significantly advance biological research. By making it affordable and accessible to biology labs, we hope to empower scientists with a powerful tool for discovery," Liu says. Dynamic applications When the researchers tested their imaging device, the light was able to penetrate more than 700 micrometers into a biological sample, whereas the best prior techniques could only reach about 200 micrometers. "With this new type of deep imaging, we want to look at biological samples and see something we have never seen before," Liu adds. The deep imaging technique enabled them to see cells at multiple levels within a living system, which could help researchers study metabolic changes that happen at different depths. In addition, the faster imaging speed allows them to gather more detailed information on how a cell's metabolism affects the speed and direction of its movements. This new imaging method could offer a boost to the study of organoids, which are engineered cells that can grow to mimic the structure and function of organs. Researchers in the Kamm and Griffith labs pioneer the development of brain and endometrial organoids that can grow like organs for disease and treatment assessment. However, it has been challenging to precisely observe internal developments without cutting or staining the tissue, which kills the sample. This new imaging technique allows researchers to noninvasively monitor the metabolic states inside a living organoid while it continues to grow. With these and other biomedical applications in mind, the researchers plan to aim for even higher-resolution images. At the same time, they are working to create low-noise laser sources, which could enable deeper imaging with less light dosage. They are also developing algorithms that react to the images to reconstruct the full 3D structures of biological samples in high resolution. In the long run, they hope to apply this technique in the real world to help biologists monitor drug response in real-time to aid in the development of new medicines. "By enabling multimodal metabolic imaging that reaches deeper into tissues, we're providing scientists with an unprecedented ability to observe nontransparent biological systems in their natural state. We're excited to collaborate with clinicians, biologists, and bioengineers to push the boundaries of this technology and turn these insights into real-world medical breakthroughs," You says. This research is funded, in part, by MIT startup funds, a U.S. National Science Foundation CAREER Award, an MIT Irwin Jacobs and Joan Klein Presidential Fellowship, and an MIT Kailath Fellowship. Story Source: Materials provided by Massachusetts Institute of Technology . Original written by Adam Zewe. Note: Content may be edited for style and length. Related Multimedia : Journal Reference : Cite This Page :
NEW YORK (AP) — U.S. stocks are drifting around their records Thursday in the runup to a big jobs report due on Friday. The crypto market had much more action, and bitcoin briefly burst to a record above $103,000 before pulling back. The S&P 500 was edging down by 0.1% after setting an all-time high for the 56th time this year the day before to improve one of its best years of the millennium . The Dow Jones Industrial Average was down 183 points, or 0.4%, with roughly an hour remaining in trading, while the Nasdaq composite was nearly unchanged from its own record set the day before. Bitcoin powered above $100,000 the night before, after President-elect Donald Trump chose a crypto advocate, Paul Atkins, as his nominee to head the Securities and Exchange Commission. The cryptocurrency has climbed dramatically from less than $70,000 on Election Day, but it quickly fell back as Thursday progressed toward $99,000, according to CoinDesk. Sharps swings for bitcoin are nothing new, and they took stocks of companies enmeshed in the crypto world on a similar ride. After rising as much as 9% in early trading, MicroStrategy, a company that’s been raising cash just to buy bitcoin, swung to a loss of 5.9%. Crypto exchange Coinbase Global fell 3.2% after likewise erasing a big early gain. Elsewhere on Wall Street, stocks of airlines helped lead the way following the latest bumps up to financial forecasts from carriers. American Airlines Group soared 18.6% after saying it’s making more in revenue during the last three months of 2024 than it expected, and it will likely make a bigger profit than it had earlier forecast. The airline also chose Citi to be its exclusive partner for credit cards that give miles in its loyalty program. That should help its cash coming in from co-branded credit card and other partners grow by about 10% annually. Southwest Airlines climbed 3.4% after saying it’s seeing stronger demand from leisure travelers than it expected. It also raised its forecast for revenue for the holiday traveling season. On the losing end of Wall Street was Synposys, which tumbled 12.1%. The supplier for the semiconductor industry reported better profit for the latest quarter than analysts expected, but it also warned of “continued macro uncertainties” and gave a forecast for revenue in the current quarter that fell short of some analysts’ estimates. American Eagle Outfitters fell even more, 15.3%, after the retailer said it’s preparing for “potential choppiness” outside of peak selling periods. It was reminiscent of a warning from Foot Locker earlier in the week and raised more concerns about how resilient U.S. shoppers can remain. Solid spending by U.S. consumers has been one of the main reasons the U.S. economy has avoided a recession that earlier seemed inevitable after the Federal Reserve hiked interest rates to crush inflation. But shoppers are now contending with still-high prices and a slowing job market . This week’s highlight for Wall Street will be Friday’s jobs report from the U.S. government, which will show how many people employers hired and fired last month. A report on Thursday said the number of U.S. workers applying for unemployment benefits rose last week but remains at historically healthy levels. Expectations are high that the Fed will cut its main interest rate again when it meets in two weeks. The Fed began easing its main interest rate from a two-decade high in September, hoping to offer more support for the job market. In the bond market, the yield on the 10-year Treasury held steady at 4.18%, where it was late Wednesday. In stock markets abroad, indexes were mostly calm in Europe after far-right and left-wing lawmakers in France joined together to vote on a no-confidence motion prompted by budget disputes that will force Prime Minister Michel Barnier and his Cabinet to resign. The CAC 40 index in Paris added 0.4%. In South Korea, the Kospi fell 0.9% to compound its 1.4% decline from the day before. President Yoon Suk Yeol was facing possible impeachment after he suddenly declared martial law on Tuesday night. He revoked the martial law declaration six hours later. Crude oil prices slipped after eight members of the OPEC+ alliance of oil exporting countries decided to put off increasing oil production. AP Business Writers Yuri Kageyama and Matt Ott contrributed.
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Lanka Milk Foods (CWE) PLC (LMF) has set an extraordinary benchmark at its Ambewela Farms, achieving a record-breaking daily milk production of 62,000 litres from a single source. This represents a truly massive growth from the 3,000 litres to 60,000 liters per day recorded. When the company took over the facility from the state sector in 2001 it started with less than 3000 liters daily production. Now contributing 20 million litres of milk annually to Sri Lanka’s national supply, Ambewela Farms exemplifies the transformative power of modernisation, expertise, and relentless dedication. This achievement is the result of years of meticulous planning, significant investments and implementing innovative farming practices. A major milestone was reached in 2019 with the introduction of two automated dairy housing and milking systems, part of a 5-billion-rupee investment in modernisation. The farms’ success stems not only from infrastructure but also from forward-thinking practices. An advanced breeding programme using sexed semen from globally renowned stud bulls has enabled the production of high-yielding cows locally. These genetically superior cows, comparable to the best commercial herds worldwide, produce an impressive 12,000 litres per 305-day lactation cycle. Nutrition also plays a vital role in sustaining these high yields. With guidance from international nutritionists, the farm employs precision feeding systems tailored to meet the needs of high-yielding cows. Additionally, purpose-bred grass varieties, imported and cultivated on the farm’s pastures, provide optimal nutrition. Advanced feeding and care systems for calves ensure superior growth and early maturity, resulting in continual improvements in herd productivity. This has resulted in dairy cows at Ambewela Farms producing an average of up to 40 litres of milk per cow, per day. General Manager Farms, Sarath Bandara said, “This milestone has been made possible through a collaborative approach, blending international expertise with the knowledge and dedication of our local teams. Having combined global knowledge with local expertise and commitment, we’ve set a new standard for dairy production in Sri Lanka. We remain committed to uplifting the dairy industry and supporting national self-sufficiency through improved productivity and quality excellence.” The impact of the developments at Ambewela Farms reaches far beyond its own operations, as LMF shares its success with local farmers by providing high-quality offspring from its herds, empowering them to enhance productivity and adopt best practices. This is improving efficiency and self-sufficiency across Sri Lanka’s dairy industry, while bolstering Island’s food security, and highlights the potential of combining advanced technology, expert guidance, and sustainable practices.
WASHINGTON (AP) — Deaths from starvation will likely pass famine levels in northern Gaza as soon as next month owing to Israel's “near-total blockade” of food and other aid, the U.S.-created global food-crisis monitor said on Tuesday. The finding by the Famine Early Warning System Network appeared to expose a rift within the Biden administration over the extent of starvation in northern Gaza, with the U.S. ambassador to Israel, Jacob Lew, disputing part of the data used in reaching the conclusion and calling the stepped-up famine warning “irresponsible." Northern Gaza has been one of the areas hardest-hit by fighting and Israel's restrictions on aid throughout its 14-month war with Hamas militants. Israel at one point increased the number of aid deliveries it permitted into northern Gaza under pressure from President Joe Biden. But the U.N. and aid groups say Israel recently has blocked almost all aid again. Only nine U.N. trucks have been able to bring in food and water over the past 2 1/2 months, Oxfam says. Israel says it has been operating in recent months against Hamas militants still active in northern Gaza. It says the vast majority of the area’s residents have fled and relocated to Gaza City, where most aid destined for the north is delivered. But some critics, including a former defense minister, have accused Israel of carrying out ethnic cleansing in Gaza’s far north, near the Israeli border. FEWS Net said unless Israel changes its policy, it expects the number of people dying of starvation and related ailments in northern Gaza to reach between two and 15 per day sometime between next month and March. The internationally recognized mortality threshold for famine is Cindy McCain, the American head of the U.N. World Food Program, in a Dec. 15 appearance on CBS' “Face the Nation” called for political pressure to get food flowing to Palestinians trapped in north Gaza. “We need unfettered access. We need a ceasefire and we need it now,” she said. “We can't ... sit by and just allow these people to starve to death.” FEWS Net was created by the U.S. Agency for International Development in the mid-1980s to warn of global food crises. The United States, Israel's main backer, provided a record amount of military support in the first year of the war. At the same time, the Biden administration repeatedly urged Israel to allow more access to aid deliveries in Gaza overall, and warned that failing to do so could trigger U.S. restrictions on military support. The administration recently said Israel was making improvements and declined to carry out its threat of restrictions. Military support for Israel's war in Gaza is politically charged in the United States. Republicans and some Democrats have staunchly opposed any effort to limit U.S. support over the suffering of Palestinian civilians trapped in the conflict. The Biden administration's reluctance to do more to press Israel for improved treatment of civilians undercut support for Democrats in last month's elections. Lew, the U.S. ambassador, challenged the famine warning in a posting on social media, saying it was based on “outdated and inaccurate” data. He pointed to uncertainty over how many of the 65,000 people remaining in northern Gaza had fled in recent weeks, saying that skewed the findings. FEWS said its famine assessment holds even if as few as 10,000 remain there. “We work day and night with the U.N. and our Israeli partners to meet humanitarian needs — which are great — and relying on inaccurate data is irresponsible.,” Lew wrote. AP writers Matthew Lee in Washington and Josef Federman in Jerusalem contributed to this report.
City slumped to their seventh defeat in 10 games in all competitions as they were beaten 2-0 at Juventus in their latest European outing on Wednesday. Second-half goals from Dusan Vlahovic and Weston McKennie at the Allianz Stadium left Guardiola’s side languishing in 22nd place in the standings. Juventus beat Man City 💪 — UEFA Champions League (@ChampionsLeague) With just two games of the league phase remaining, a place in the top eight and automatic last-16 qualification looks beyond them and they face a battle just to stay in the top 24 and claim a play-off spot. City manager Guardiola said: “Of course I question myself but I’m stable in good moments and bad moments. “I try to find a way to do it. I’m incredibly honest. If we play good (I say) we played good and today I thought we played good. “Our game will save us. We can do it. We conceded few chances compared to the Nottingham Forest game that we won. We’re making the right tempo. “We missed the last pass, did not arrive in the six-yard box (at the right time) or have the composure at the right moment. “But I love my team. This is life, it happens. Sometimes you have a bad period but I’m going to insist until we’re there.” City now face a crunch trip to Paris St Germain, who are also at risk of failing to qualify, next month. Guardiola accepts the top 24 is now the only aim. He said: “It’s the target. We need one point or three points. We go to Paris to try to do it and the last game at home.” Veteran midfielder Ilkay Gundogan said after the game he felt City were suffering from a loss of confidence but Guardiola dismissed his player’s comments. “I am not agreeing with Ilkay,” he said. “Of course it is tough but, except one or two games in this period, we’ve played good.” City now face a further test of their resolve as they host rivals Manchester United in a derby on Sunday. "We played well" Pep Guardiola trusts in his squad despite 2-0 loss to Juventus... 📺 & — Football on TNT Sports (@footballontnt) Gundogan told TNT Sports: “It (confidence) is a big part of it. That’s a mental issue as well. “You can see that sometimes we miss the ball or lose a duel and you see that we drop immediately and lose the rhythm. They (the opponents) don’t even need to do much but it has such a big effect on us right now. “Even more you have to do the simple things as good as possible and create and fluidity, then it’s work hard again. This is how you get confidence back – do the small and simple things, (but) in crucial moments at the moment we are always doing the wrong things.” Juventus coach Thiago Motta was pleased with the hosts’ performance, which boosted their hopes of making the top eight. “It was a deserved victory,” he said. “We had to defend as a team and be ready to attack with quality. “We have shown we can compete at this level and now we have to do it consistently.”Forget CBA and buy these ASX 200 dividend sharesNHL on Sportsnet: Panthers vs. Flyers