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SAN FRANCISCO (AP) — A 7.0 magnitude earthquake shook a large area of Northern California on Thursday, knocking items of grocery store shelves, sending children scrambling under desks and prompting a brief tsunami warning for 5.3 million people along the U.S. West Coast. The quake struck at 10:44 a.m. west of Ferndale, a small city in coastal Humboldt County, about 130 miles (209 km) from the Oregon border, the U.S. Geological Survey said. It was felt as far south as San Francisco, some 270 miles (435 km) away, where residents felt a rolling motion for several seconds. It was followed by multiple smaller aftershocks. There were no immediate reports of major damage or injury. The tsunami warning was in effect for roughly an hour. It was issued shortly after the temblor struck and covered nearly 500 miles (805 km) of coastline, from the edge of California’s Monterey Bay north into Oregon. “It was a strong quake, our building shook, we’re fine but I have a mess to clean up right now,” said Julie Kreitzer, owner of Golden Gait Mercantile, a store packed with food, wares and souvenirs that is a main attraction in Ferndale. “We lost a lot of stuff. It’s probably worse than two years ago. I have to go, I have to try and salvage something for the holidays because it’s going to be a tough year,” Kreitzer said before hanging up. The region — known for its redwood forests, scenic mountains and the three-county Emerald Triangle’s legendary marijuana crop — was struck by a 6.4 magnitude quake in 2022 that left thousands of people without power and water. The northwest corner of California is the most seismically active part of the state since it’s where three tectonic plates meet, seismologist Lucy Jones said on the social media platform BlueSky. Shortly after the quake, phones in Northern California buzzed with the tsunami warning from the National Weather Service that said: “A series of powerful waves and strong currents may impact coasts near you. You are in danger. Get away from coastal waters. Move to high ground or inland now. Keep away from the coast until local officials say it is safe to return.” South of San Francisco in Santa Cruz, authorities cleared the main beach, taping off entrances with police tape. Numerous cities urged people to evacuate to higher ground as a precaution, including Eureka. “I thought my axles had fallen apart,” said Valerie Starkey, a Del Norte County supervisor representing Crescent City, a town of fewer than 6,000 about 66 miles (106 km) north of Eureka. “That’s what I was feeling ... ‘My axles are broken now.’ I did not realize it was an earthquake.” Gov. Gavin Newsom said he has signed off on a state of emergency declaration to quickly move state resources to impacted areas along the coast. State officials were concerned about damages in the northern part of the state, Newsom said. Crews in Eureka, the biggest city in the region, were assessing if there was any major damage from the quake, Eureka Mayor Kim Bergel said. Bergel, who works as a resource aid at a middle school, said lights were swaying and everyone got under desks. “The kids were so great and terrified. It seemed to go back and forth for quite a long time,” she said. Some children asked, “Can I call my mom?" The students were later sent home. In nearby Arcata, students and faculty were urged to shelter in place at California State Polytechnic University, Humboldt. The campus in was not in the tsunami hazard zone and after inspections, “all utilities and building systems are normal and operational,” the university said in a statement. Humboldt County Sheriff William Honsal said residents experienced some cracks in their homes’ foundations, as well as broken glass and windows, but nothing severe. There also have been no major infrastructure problems, building collapses or roadway issues, and no major injuries or deaths have been reported, he said. Honsal said he was in his office in the 75-year-old courthouse in downtown Eureka when he felt the quake. “We’re used to it. It is known as ‘earthquake country’ up here,” he said. “It wasn’t a sharp jolt. It was a slow roller, but significant.” Michael Luna, owner of a Grocery Outlet in Eureka, said that besides a few items falling off shelves, the store on Commercial Street was unscathed by the earthquake. “We didn’t have any issues but a couple of deodorants fall off.... I think the way the earthquake rumbled this time, it was a good thing for our store because the last earthquake was a huge mess," he said. They evacuated customers and closed their doors temporarily until officials lifted the tsunami warning, he said, rushing off the phone to attend to a growing line of customers at check-out. The San Francisco Bay Area Rapid Transit District, known as BART, stopped traffic in all directions through the underwater tunnel between San Francisco and Oakland, and the San Francisco Zoo’s visitors were evacuated. Dave Snider, tsunami warning coordinator for the Tsunami Warning Center in Alaska, said the computer models indicated that this was the type of earthquake that was unlikely to cause a tsunami and gauges that monitor waves then confirmed it, so forecasters canceled the warning. This quake was a strike-slip type of temblor that shifts more horizontally and is less prone to cause tsunamis, unlike the more vertical types, said National Weather Service tsunami program manager Corina Allen in Washington state. The California Geological Survey says the state’s shores have been struck by more than 150 tsunamis since 1800, and while most were minor, some have been destructive and deadly. On March 28, 1964, a tsunami triggered by a powerful earthquake in Alaska smashed into Crescent City hours later. Much of the business district was leveled and a dozen people were killed. More recently, a tsunami from a 2011 earthquake in Japan caused about $100 million in damages along the California coast, much of it in Crescent City. Dazio reported from Los Angeles. AP writers Chris Weber and Dorany Pineda in Los Angeles; Martha Mendoza in Santa Cruz, California; Sophie Austin and Tran Nguyen in Sacramento, California and Seth Borenstein in Washington, D.C. contributed to this report.A range of independent TDs are contemplating the prospect of entering Ireland’s next coalition government as Fianna Fail and Fine Gael consider ways to secure a solid majority. Three long days of counting in the General Election finished late on Monday night when the final two seats were declared in the constituency of Cavan-Monaghan. Fianna Fail was the clear winner of the election, securing 48 of the Dail parliament’s 174 seats. Sinn Fein took 39 and Fine Gael 38. Labour and the Social Democrats both won 11 seats; People Before Profit-Solidarity took three; Aontu secured two; and the Green Party retained only one of its 12 seats. Independents and others accounted for 21 seats. The return of a Fianna Fail/Fine Gael-led coalition is now highly likely. However, their combined seat total of 86 leaves them just short of the 88 needed for a majority in the Dail. While the two centrist parties that have dominated Irish politics for a century could look to strike a deal with one of the Dail’s smaller centre-left parties, such as the Social Democrats or Labour, a more straightforward route to a majority could be achieved by securing the support of several independent TDs. For Fianna Fail leader Micheal Martin and current taoiseach and Fine Gael leader Simon Harris, wooing like-minded independents would be likely to involve fewer policy concessions, and financial commitments, than would be required to convince another party to join the government benches. Longford-Westmeath independent TD Kevin “Boxer” Moran, who served in a Fine Gael-led minority government between 2017 and 2020, expressed his willingness to listen to offers to join the new coalition in Dublin. “Look, my door’s open,” he told RTE. “Someone knocks, I’m always there to open it.” Marian Harkin, an independent TD for Sligo-Leitrim, expressed her desire to participate in government as she noted that Fianna Fail and Fine Gael were within “shouting distance” of an overall majority. “That means they will be looking for support, and I certainly will be one of those people who will be speaking to them and talking to them and negotiating with them, and I’m looking forward to doing that, because that was the reason that I ran in the first place,” she said. Meanwhile, the Social Democrats and Irish Labour Party both appear cautious about the prospect of an alliance with Fianna Fail and Fine Gael. They will no doubt be mindful of the experience of the Green Party, the junior partner in the last mandate. The Greens experienced near wipeout in the election, retaining only one of their 12 seats. Sinn Fein appears to currently have no realistic route to government, given Fianna Fail and Fine Gael’s ongoing refusal to share power with the party. Despite the odds being stacked against her party, Sinn Fein president Mary Lou McDonald contacted the leaders of the Social Democrats and Labour on Monday to discuss options. Earlier, Fianna Fail deputy leader and outgoing Finance Minister Jack Chambers predicted that a new coalition government would not be in place before Christmas. Mr Chambers said planned talks about forming an administration required “time and space” to ensure that any new government will be “coherent and stable”. After an inconclusive outcome to the 2020 election, it took five months for Fianna Fail, Fine Gael and the Greens to strike the last coalition deal. Mr Chambers said he did not believe it would take that long this time, as he noted the Covid-19 pandemic was a factor in 2020, but he also made clear it would not be a swift process. He said he agreed with analysis that there was no prospect of a deal before Christmas. “I don’t expect a government to be formed in mid-December, when the Dail is due to meet on December 18, probably a Ceann Comhairle (speaker) can be elected, and there’ll have to be time and space taken to make sure we can form a coherent, stable government,” he told RTE. “I don’t think it should take five months like it did the last time – Covid obviously complicated that. But I think all political parties need to take the time to see what’s possible and try and form a stable government for the Irish people.” Fine Gael minister of state Peter Burke said members of his parliamentary party would have to meet to consider their options before giving Mr Harris a mandate to negotiate a new programme for government with Fianna Fail. “It’s important that we have a strong, stable, viable government, whatever form that may be, to ensure that we can meet the challenges of our society, meet the challenges in terms of the economic changes that are potentially going to happen,” he told RTE. Despite being set to emerge with the most seats, it has not been all good news for Fianna Fail. The party’s outgoing Health Minister Stephen Donnelly became one of the biggest casualties of the election when he lost his seat in Wicklow in the early hours of Monday morning. Mr Donnelly was always predicted to face a fight in the constituency after boundary changes saw it reduced from five to four seats. If it is to be a reprise of the Fianna Fail/Fine Gael governing partnership of the last mandate, one of the major questions is around the position of taoiseach and whether the parties will once again take turns to hold the Irish premiership during the lifetime of the new government. The outcome in 2020 saw the parties enter a coalition on the basis that the holder of the premier position would be exchanged midway through the term. Fianna Fail leader Mr Martin took the role for the first half of the mandate, with Leo Varadkar taking over in December 2022. Current Fine Gael leader Mr Harris succeeded Mr Varadkar as taoiseach when he resigned from the role earlier this year. However, this time Fianna Fail has significantly increased its seat lead over Fine Gael, compared with the last election when there were only three seats between the parties. The size of the disparity in party numbers is likely to draw focus on the rotating taoiseach arrangement, raising questions as to whether it will be re-run in the next coalition and, if it is, on what terms. On Sunday, Simon Coveney, a former deputy leader of Fine Gael, said a coalition that did not repeat the rotating taoiseach arrangement in some fashion would be a “difficult proposition” for his party. Meanwhile, Fine Gael minister Paschal Donohoe said he would be making the case for Mr Harris to have another opportunity to serve as taoiseach. On Monday, Mr Chambers said while his party would expect to lead the government it would approach the issue of rotating the taoiseach’s role on the basis of “mutual respect” with Fine Gael. “I think the context of discussions and negotiations will be driven by mutual respect, and that’s the glue that will drive a programme for government and that’s the context in which we’ll engage,” he said. On Monday, Labour leader Ivana Bacik reiterated her party’s determination to forge an alliance with fellow centre-left parties with the intention of having a unified approach to the prospect of entering government. Asked if Labour was prepared to go into government with Fianna Fail and Fine Gael on its own, she told RTE: “No, not at this stage. We are absolutely not willing to do that. “We want to ensure there’s the largest number of TDs who share our vision and our values who want to deliver change on the same basis that we do.” The Social Democrats have been non-committal about any potential arrangement with Fianna Fail and Fine Gael, and have restated a series of red lines they would need to achieve before considering taking a place in government. Leader Holly Cairns, who gave birth to a daughter on polling day on Friday, said in a statement: “The party is in a very strong position to play an important role in the next Dail. In what position, government or opposition, remains to be seen.” Fianna Fail secured the most first preference votes in Friday’s proportional representation election, taking 21.9% to Fine Gael’s 20.8%. Sinn Fein came in third on 19%. While Sinn Fein’s vote share represented a marked improvement on its disappointing showing in June’s local elections in Ireland, it is still significantly down on the 24.5% poll-topping share it secured in the 2020 general election. The final breakdown of first preferences also flipped the result of Friday night’s exit poll, which suggested Sinn Fein was in front on 21.1%, with Fine Gael on 21% and Fianna Fail on 19.5%.magic wonderland ocean 。

Fruit Cultivation Global Market Report 2024: A Comprehensive Overview and Projections

TORONTO (AP) — Prime Minister Justin Trudeau told Donald Trump that Americans would also suffer if the president-elect follows through on a plan to impose sweeping tariffs on Canadian products , a Canadian minister who attended their recent dinner said Monday. Trump threatened to impose tariffs on products from Canada and Mexico if they don’t stop what he called the flow of drugs and migrants across their borders with the United States. He said on social media last week that he would impose a 25% tax on all products entering the U.S. from Canada and Mexico as one of his first executive orders. Canadian Public Safety Minister Dominic LeBlanc, whose responsibilities include border security, attended a dinner with Trump and Trudeau at Trump’s Mar-a-Lago club on Friday. Trudeau requested the meeting in a bid to avoid the tariffs by convincing Trump that the northern border is nothing like the U.S. southern border with Mexico . "The prime minister of course spoke about the importance of protecting the Canadian economy and Canadian workers from tariffs, but we also discussed with our American friends the negative impact that those tariffs could have on their economy, on affordability in the United States as well," LeBlanc said in Parliament. If Trump makes good on his threat to slap 25% tariffs on everything imported from Mexico and Canada, the price increases that could follow will collide with his campaign promise to give American families a break from inflation. Economists say companies would have little choice but to pass along the added costs, dramatically raising prices for food, clothing, automobiles, alcohol and other goods. The Produce Distributors Association, a Washington trade group, said last week that tariffs will raise prices for fresh fruit and vegetables and hurt U.S. farmers when the countries retaliate. Canada is already examining possible retaliatory tariffs on certain items from the U.S. should Trump follow through on the threat. After his dinner with Trump, Trudeau returned home without assurances the president-elect will back away from threatened tariffs on all products from the major American trading partner. Trump called the talks “productive” but signaled no retreat from a pledge that Canada says unfairly lumps it in with Mexico over the flow of drugs and migrants into the United States. “The idea that we came back empty handed is completely false,” LeBlanc said. “We had a very productive discussion with Mr. Trump and his future Cabinet secretaries. ... The commitment from Mr. Trump to continue to work with us was far from empty handed.” Joining Trump and Trudeau at dinner were Howard Lutnick, Trump’s nominee for commerce secretary, North Dakota Gov. Doug Burgum, Trump’s pick to lead the Interior Department, and Mike Waltz, Trump’s choice to be his national security adviser. Canada’s ambassador to the U.S., Kirsten Hillman, told The Associated Press on Sunday that “the message that our border is so vastly different than the Mexican border was really understood.” Hillman, who sat at an adjacent table to Trudeau and Trump, said Canada is not the problem when it comes to drugs and migrants. On Monday, Mexico’s president rejected those comments. “Mexico must be respected, especially by its trading partners,” President Claudia Sheinbaum said. She said Canada had its own problems with fentanyl consumption and “could only wish they had the cultural riches Mexico has.” Flows of migrants and seizures of drugs at the two countries’ border are vastly different. U.S. customs agents seized 43 pounds of fentanyl at the Canadian border during the last fiscal year, compared with 21,100 pounds at the Mexican border. Most of the fentanyl reaching the U.S. — where it causes about 70,000 overdose deaths annually — is made by Mexican drug cartels using precursor chemicals smuggled from Asia. On immigration, the U.S. Border Patrol reported 1.53 million encounters with migrants at the southwest border with Mexico between October 2023 and September 2024. That compares to 23,721 encounters at the Canadian border during that time. Canada is the top export destination for 36 U.S. states. Nearly $3.6 billion Canadian (US$2.7 billion) worth of goods and services cross the border each day. About 60% of U.S. crude oil imports are from Canada, and 85% of U.S. electricity imports as well. Canada is also the largest foreign supplier of steel, aluminum and uranium to the U.S. and has 34 critical minerals and metals that the Pentagon is eager for and investing for national security.NEW YORK (AP) — U.S. stock indexes got back to climbing on Wednesday after the latest update on inflation appeared to clear the way for more help for the economy from the Federal Reserve. The S&P 500 rose 0.8% to break its first two-day losing streak in nearly a month and finished just short of its all-time high. Big Tech stocks led the way, which drove the Nasdaq composite up 1.8% to top the 20,000 level for the first time. The Dow Jones Industrial Average, meanwhile, lagged the market with a dip of 99 points, or 0.2%. Stocks got a boost as expectations built that Wednesday's inflation data will allow the Fed to deliver another cut to interest rates at its meeting next week. Traders are betting on a nearly 99% probability of that, according to data from CME Group, up from 89% a day before. If they're correct, it would be a third straight cut by the Fed after it began lowering rates in September from a two-decade high. It's hoping to support a slowing job market after getting inflation nearly all the way down to its 2% target. Lower rates would give a boost to the economy and to prices for investments, but they could also provide more fuel for inflation. "The data have given the Fed the 'all clear' for next week, and today's inflation data keep a January cut in active discussion," according to Ellen Zentner, chief economic strategist for Morgan Stanley Wealth Management. Expectations for a series of cuts to rates by the Fed have been one of the main reasons the S&P 500 has set an all-time high 57 times this year, with the latest coming last week. The biggest boosts for the index on Wednesday came from Nvidia and other Big Tech stocks. Their massive growth has made them Wall Street's biggest stars for years, though other kinds of stocks have recently been catching up somewhat amid hopes for the broader U.S. economy. Tesla jumped 5.9% to finish above $420 at $424.77. It's a level that Elon Musk made famous in a 2018 tweet when he said he had secured funding to take Tesla private at $420 per share. Stitch Fix soared 44.3% after the company that sends clothes to your door reported a smaller loss for the latest quarter than analysts expected. It also gave financial forecasts for the current quarter that were better than expected, including for revenue. GE Vernova rallied 5% for one of the biggest gains in the S&P 500. The energy company that spun out of General Electric said it would pay a 25 cent dividend every three months, and it approved a plan to send up to another $6 billion to its shareholders by buying back its own stock. On the losing end of Wall Street, Dave & Buster's Entertainment tumbled 20.1% after reporting a worse loss for the latest quarter than expected. It also said CEO Chris Morris has resigned, and the board has been working with an executive-search firm for the last few months to find its next permanent leader. Albertsons fell 1.5% after filing a lawsuit against Kroger, saying it didn't do enough for their proposed $24.6 billion merger agreement to win regulatory clearance. Albertsons said it's seeking billions of dollars in damages from Kroger, whose stock rose 1%. A day earlier, judges in separate cases in Oregon and Washington nixed the supermarket giants' merger. The grocers contended a combination could have helped them compete with big retailers like Walmart, Costco and Amazon, but critics said it would hurt competition. After terminating the merger agreement with Kroger, Albertsons said it plans to boost its dividend 25% and increased the size of its program to buy back its own stock. Macy's slipped 0.8% after cutting some of its financial forecasts for the full year of 2024, including for how much profit it expects to make off each $1 of revenue. All told, the S&P 500 rose 49.28 points to 6,084.19. The Dow dipped 99.27 to 44,148.56, and the Nasdaq composite rallied 347.65 to 20,034.89. In the bond market, the yield on the 10-year Treasury rose to 4.27% from 4.23% late Tuesday. The two-year Treasury yield, which more closely tracks expectations for the Fed, edged up to 4.15% from 4.14%. In stock markets abroad, indexes rose across much of Europe and Asia. Hong Kong's Hang Seng was an outlier and slipped 0.8% as Chinese leaders convened an annual planning meeting in Beijing that is expected to set economic policies and growth targets for the coming year. South Korea's Kospi rose 1%, up for a second straight day as it climbs back following last week's political turmoil where its president briefly declared martial law.

AVS Global strengthens Asia-Pacific operations through new Sri Lanka office

Chinese Vice President Han Zheng met with Deputy Prime Minister and Foreign Minister of Vietnam Bui Thanh Son in Beijing. Photo: Xinhua On Tuesday, Chinese Vice President Han Zheng met with Deputy Prime Minister and Foreign Minister of Vietnam Bui Thanh Son in Beijing. Noting that next year marks the 75th anniversary of the establishment of diplomatic relations between the two countries and the China-Vietnam Year of People-to-People Exchanges, Han said the two sides should follow the important consensus reached by the top leaders of the two parties and two countries, maintain strategic communication, expand practical cooperation, consolidate the foundation of public opinion, strengthen multilateral coordination and promote the building of a China-Vietnam community with a shared future, bringing more benefits to the two peoples. Bui Thanh Son said that developing long-term friendly relations with China is the consistent proposition, objective requirement, strategic choice and top priority of Vietnam's diplomacy. Vietnam firmly adheres to the one-China policy and is willing to strengthen high-level exchanges, consolidate political mutual trust, deepen pragmatic cooperation with China, and jointly promote the building of a Vietnam-China community with a shared future with strategic significance, he added. Also on Tuesday, Member of the Political Bureau of the CPC Central Committee and Minister of Foreign Affairs Wang Yi and Bui Thanh Son co-chaired the 16th meeting of the China-Vietnam Steering Committee for Bilateral Cooperation in Beijing. Wang said that in December last year, Xi Jinping, general secretary of the Communist Party of China (CPC) Central Committee and Chinese president, made a historic visit to Vietnam, and in August this year, To Lam, general secretary of the Communist Party of Vietnam (CPV) Central Committee and Vietnamese president, successfully visited China, as the top leaders of the two parties and countries reached an important consensus on advancing the construction of a China-Vietnam community with a shared future. Over the past year, various departments and localities of both countries have actively implemented this consensus, promoting fruitful results in China-Vietnam comprehensive strategic cooperation. This not only benefits the two parties, the two countries, and their peoples, but also adds stability and certainty to a world filled with turmoil and uncertainty, Wang said. Wang and Bui Thanh Son also attended the commemorating event for the 25th anniversary of the demarcation of the land boundary between China and Vietnam and the 15th anniversary of the signing of the three legal documents. Gu Xiaosong, dean of the ASEAN Research Institute at Hainan Tropical Ocean University, told the Global Times that meetings between senior officials from China and Vietnam are constructive to accelerate the implementation of the consensus reached by the two heads of state, enhance political mutual trust and improve the quality of cooperation in fields like infrastructure, trade and investment. Given the increasingly complex geopolitical landscape, Gu noted that the stable China-Vietnam relationship is of great significance to regional peace and eliminating external interference. Xu Liping, director of the Center for Southeast Asian Studies at the Chinese Academy of Social Sciences, told the Global Times that interaction between the two countries will serve as a link between the past and the future, laying the groundwork for the celebration of the 75th anniversary of the establishment of China-Vietnam diplomatic ties in 2025. The experience of China and Vietnam in settling their land border issue through peaceful negotiations has proved that the two countries have the wisdom and ability to manage their differences, which adds confidence that maritime differences can be resolved, especially as Malaysia, chair of ASEAN in 2025, has expressed hope that the South China Sea Code of Conduct (COC) can be finalized, Xu said. Although China and Vietnam are facing an increasingly complex geopolitical environment, the pragmatic cooperation between two sides is unlikely to be affected despite differences, Xu said. China and Vietnam have had frequent and positive interactions in various fields recently. On December 4, two fleets from the Chinese and Vietnamese navies concluded a two-day joint patrol in the Beibu Gulf, which was of great significance to deepening the mutual trust and cooperation between the two militaries, according to the Xinhua News Agency. Bui Thanh Son on Monday visited Zhongguancun, which is known as China's "Silcom Valley" in northwestern Beijing as a hub for fostering cutting-edge and high-tech enterprises, according to Vietnam Government News. China-Vietnam relations are sustainable and continuous, and the latest interactions between senior official from both sides will lay a more solid foundation for the continuous development of bilateral relations in the future, Xu said.

FACT FOCUS: Vermont ruling does not say schools can vaccinate children without parental consent

DALLAS — 70 Native American athletes from across the United States will compete in the 2025 Native American All-Star Football Game on Jan. 7, 2025, at the Ford Center at The Star in Frisco, Texas. Organized by the Native American Athletic Foundation (NAAF) in collaboration with the National Football League (NFL) and Nike, the event will spotlight top talent while fostering growth on and off the field for an immersive experience. From Jan. 3-7, 2025, participants will receive elite coaching, preparation for college athletics, leadership training, life skills and positive coping tools, all designed to inspire and prepare them for future success. “We are excited and honored to work with the NFL to make an impact in the lives of Native athletes,” said Michael Stopp, Executive Director, NAAF. “Our organization was established to use sports to develop the next generation of leaders in Indian Country. This partnership and this year’s game take an important step forward in meeting our mission.” The NAAF is a nonprofit, which is devoted to creating athletic and educational opportunities for Native youth. NFL Vice President of Football Development, Roman Oben, said the Native American All-Star game will celebrate diversity while fostering the development of the next generation of leaders. “Through this partnership, we aim to create a lasting impact by giving Native athletes the same opportunities to succeed both on and off the field,” Oben said. “This also reflects the NFL’s commitment to building character, promoting inclusivity and strengthening communities across the country.” Nike will be providing the uniforms for the all-star game and camp. They are trying to help grow football among Native American and Indigenous youth. This initiative ties into Nike’s N7 Collection, where they are “celebrating Indigenous culture and its interconnectedness with nature while helping preserve and showcase Native traditions for generations to come.” The term N7 is inspired by the “Seventh Generation Principle,” a philosophy from the Haudenosaunee. It asserts that decisions made today should lead to a sustainable world seven generations into the future. “As a champion for athletes and sport, Nike is committed to building inclusive communities, breaking down barriers to access for athletes around the world, and expanding sport for the next generation,” said Scott Henson, Nike brand director. ©2024 The Dallas Morning News. Visit dallasnews.com . Distributed by Tribune Content Agency, LLC.

Astronaut Suni Williams and AstrobeeChuck Woolery, smooth-talking game show host of 'Love Connection' and 'Scrabble,' dies at 83VitaGraft KidneyTM quantifies the amount of DNA fragments in transplant patients' blood that originate from the donor organ, a key biomarker for assessing graft health. This process is commonly referred to as donor-derived cell-free DNA (dd-cfDNA) testing and is widely used in clinical practice today. In this latest study, Oncocyte's proprietary diagnostic dd-cfDNA test using digital PCR was able to diagnose antibody-mediated rejection (AMR) in kidney transplant recipients nearly a year ahead of standard protocols 1 . "We are excited to see our dd-cfDNA technology demonstrate strong predictive value for AMR, supporting clinicians in identifying AMR in patients sooner, thereby enhancing the opportunity for better outcomes,” said Oncocyte Chief Science Officer Dr. Ekkehard Schuetz. "The trial's results further validate dd-cfDNA as a critical biomarker that can bridge diagnostic gaps for transplant patients.” For further context, de-novo donor specific antibody (dnDSA) is a routine biomarker used in kidney transplant management. The appearance of dnDSA in a patient -- that is, the patient is found to be dnDSA-positive (dnDSA+) -- signals an increased risk of AMR. This latest study shows that compared to standard of care, VitaGraft Kidney can significantly reduce the time to diagnosis of AMR in dnDSA+ patients. It is also the first randomized interventional study to validate any dd-cfDNA technology as a rule-in test for biopsy in a high-risk population. Catching AMR early, when kidney graft loss can be minimized, is becoming increasingly important as physicians explore the use of drugs, including the anti-CD38 drugs felzartamab and daratumumab, to manage rejection. Monitoring with VitaGraft in this high-risk patient population could support early intervention with these new therapeutic options. Once patients are on therapy, monitoring for therapeutic efficacy is also important to manage potential unwanted side effects. Publications using VitaGraft to monitor for efficacy for both aforementioned drugs can be found in the New England Journal of Medicine and Transplant International . In addition, earlier this year, Oncocyte signed an agreement with a European biotechnology company to be the provider of dd-cfDNA testing for a Phase II clinical trial for a separate therapeutic in AMR. Oncocyte expects to submit for claims expansion to its payor, MolDX 2 , to support the use of VitaGraft for these high-risk patients in the clinic. If granted, it would expand the use case beyond the current for-cause claim, opening significant new revenue opportunities. In sum, this clinical trial provides compelling evidence for dd-cfDNA monitoring as a tool for enhancing early intervention and improving outcomes for patients at increased risk of transplant rejection. Oncocyte scientists and inventors of the technology, Dr. Schuetz, Julia Beck and Kirsten Bornemann-Kolatzki, co-authored the study, which was initiated by researchers at Charité - Universitätsmedizin Berlin under the leadership of Prof. Klemens Budde. The study was published in Nephrology Dialysis Transplantation: Oxford Academic and may be found by accessing this link. Additional study details: Highlighting potential for improved patient outcomes, as well as implications for broader clinical applications and future therapies The interventional randomized trial, conducted between June 2021 and July 2023, involved 40 kidney transplant recipients with dnDSA, assessing longitudinal dd-cfDNA monitoring as a guiding tool for diagnostic biopsy compared to standard clinical practices. Oncocyte's proprietary dd-cfDNA technology was able to detect the onset of AMR significantly earlier in patients by guiding the indication for biopsy (median time from inclusion to diagnosis: 2.8 months) compared to the control group using standard of care (14.5 months). As noted above, this early intervention could offer a valuable advantage in transplant care by enabling prompt treatment before irreversible damage occurs. "This study underscores the impact of dd-cfDNA as a critical biomarker for early AMR detection, providing healthcare teams with timely data enabling them to initiate treatments sooner," said Dr. Aylin Akifova, first author from Charité. This study also suggests that dd-cfDNA monitoring could also be instrumental in identifying subclinical AMR-a silent condition that, if undiagnosed, can lead to significant graft damage. Additionally, the findings come at a crucial time, as mentioned above, as promising new treatments, including CD38-targeted therapies, are showing unprecedented efficacy in treating AMR. Early diagnosis with dd-cfDNA could provide the earliest window for intervention, offering an advantage for patients suffering from AMR, a disease with historically very limited treatment options. "We congratulate Charité's research teams on these compelling findings, which further underscore our mission to empower clinicians with tools for precision diagnostics while also democratizing access to novel molecular diagnostic testing to improve patient outcomes,” said Josh Riggs, CEO of Oncocyte. "We look forward to expanding the clinical applications of dd-cfDNA technology and supporting transplant communities worldwide with our innovative diagnostic solutions.” About Oncocyte Oncocyte is a diagnostics technology company. The Company's tests are designed to help provide clarity and confidence to physicians and their patients. VitaGraftTM is a clinical blood-based solid organ transplantation monitoring test. GraftAssureTM is a research use only (RUO) blood-based solid organ transplantation monitoring test. DetermaIOTM is a gene expression test that assesses the tumor microenvironment to predict response to immunotherapies. DetermaCNITM is a blood-based monitoring tool for monitoring therapeutic efficacy in cancer patients. For more information about Oncocyte, please visit https://oncocyte.com/ . For more information about our products, please visit the following web pages: VitaGraft KidneyTM - https://oncocyte.com/vitagraft-kidney/ VitaGraft LiverTM - https://oncocyte.com/vitagraft-liver/ GraftAssureTM - https://oncocyte.com/graftassure/ DetermaIOTM - https://oncocyte.com/determa-io/ DetermaCNITM - https://oncocyte.com/determa-cni/ VitaGraftTM, GraftAssureTM, DetermaIOTM, and DetermaCNITM are trademarks of Oncocyte Corporation. CONTACT: Jeff Ramson PCG Advisory (646) 863-6893 [email protected] Forward-Looking Statements Any statements that are not historical fact (including but not limited to statements that contain words such as "will,” "believes,” "plans,” "anticipates,” "expects,” "estimates,” "may,” and similar expressions) are forward-looking statements. These statements include those pertaining to, among other things, the expectation that Oncocyte will submit for claims expansion to MolDX to support the use of VitaGraft for high-risk patients in the clinic, which may expand the use case and open significant new revenue opportunities, the company's anticipated expansion of clinical applications of dd-cfDNA technology, the company's goal to support transplant communities worldwide with its innovative diagnostic solutions, and other statements about the future expectations, beliefs, goals, plans, or prospects expressed by management. Forward-looking statements involve risks and uncertainties, including, without limitation, risks inherent in the development and/or commercialization of diagnostic tests or products, uncertainty in the results of clinical trials or regulatory approvals, the capacity of Oncocyte's third-party supplied blood sample analytic system to provide consistent and precise analytic results on a commercial scale, potential interruptions to supply chains, the need and ability to obtain future capital, maintenance of intellectual property rights in all applicable jurisdictions, obligations to third parties with respect to licensed or acquired technology and products, the need to obtain third party reimbursement for patients' use of any diagnostic tests Oncocyte or its subsidiaries commercialize in applicable jurisdictions, and risks inherent in strategic transactions such as the potential failure to realize anticipated benefits, legal, regulatory or political changes in the applicable jurisdictions, accounting and quality controls, potential greater than estimated allocations of resources to develop and commercialize technologies, or potential failure to maintain any laboratory accreditation or certification. Actual results may differ materially from the results anticipated in these forward-looking statements and accordingly such statements should be evaluated together with the many uncertainties that affect the business of Oncocyte, particularly those mentioned in the "Risk Factors” and other cautionary statements found in Oncocyte's Securities and Exchange Commission (SEC) filings, which are available from the SEC's website. You are cautioned not to place undue reliance on forward-looking statements, which speak only as of the date on which they were made. Oncocyte undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made, except as required by law.

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Charred remains of Vladimir Putin's 8,370mph hypersonic Oreshnik missile retrieved by Ukraine after despot's boasts that 'no one in the world has such weapons' By TARYN PEDLER Published: 11:01 EST, 24 November 2024 | Updated: 11:28 EST, 24 November 2024 e-mail 5 View comments The charred remains of Putin 's hypersonic Oreshnik missile have been retrieved by Ukraine after the despot boasted that 'no one in the world has such weapons'. The debris from the medium-range ballistic missile that was fired at the city of Dnipro on Thursday is being studied by Ukrainian investigators as it historically became the first time such a powerful weapon has been used in the war. Pieces of the nuclear-capable weapon were found scorched and shredded on the ground in a hangar at a facility which conducts weapons forensics. Russia has named the missile the Oreshnik - meaning Hazel Tree - and have previously claimed it is impossible to intercept it with air defences. Ukraine said the weapon reached a top speed of more than 8,000mph as it headed towards Dnipro on November 21. Intermediate-range ballistic missiles have a range of up to 5,500km and Ukrainian experts study their debris to gain insight into Russian military supply chains, production, and how to develop counter-measures. Two unnamed state experts provided cautious assessments, saying only that the weapon was ballistic, flew on a ballistic trajectory, and that the strike resulted in civilian damage. 'These are preliminary conclusions and to say something more concrete requires time and careful study of the remains of the missile,' Ivan, one of the experts, told Reuters. Fragments of a rocket which struck Dnipro on November 21 are seen at a center for forensic analysis in an undisclosed location in Ukraine, November 24 Pieces of the nuclear-capable weapon were found scorched and shredded on the ground in a hangar at a facility which conducts weapons forensics Russia on November 21 fired an experimental missile at Ukraine, officials from Western governments said. Ukraine initially accused Russia of firing in an attack on Dnipro an intercontinental ballistic missile (ICBM) in combat for the first time in history A grab taken from handout footage released by the Russian Defence Ministry on March 1, 2024 purport to show the test firing of an ICBM belonging to the country's nuclear deterrence forces 'This is the first time that such remnants of such a missile have been discovered on the territory of Ukraine,' added Oleh, an investigator for the Security Service of Ukraine. Ukrainian President Volodymyr Zelensky has called the use of the weapon, which is capable of carrying multiple nuclear warheads, a severe escalation and urged his allies to respond. Ukraine originally said the weapon appeared to be an intercontinental ballistic missile. The Kremlin later said it fired a new intermediate-range missile at a Ukrainian military target in Dnipro in response to Kyiv striking Russia with US and British made missiles for the first time after the US granted its approval. Read More Putin ramps up production of Russia's 8,370mph hypersonic missiles that he fired at Ukraine The US military has said the missile's design is based on the longer-range RS-26 Rubezh intercontinental ballistic missile (ICBM). The new missile was experimental and Russia likely possessed only a handful of them, they have said. If the missile was launched from the Kapustin Yar range in Russia's southern Astrakhan region, as it was in yesterday's strike on Ukraine, Putin could still comfortably hit any target in Europe or the UK without having to turn to his most powerful weapons. Targets in London would go up in flames in under 20 minutes while Berlin further east would have less than 15 minutes before impact. Russian President Vladimir Putin said on Friday Moscow would keep testing the missile in combat and had a stock ready to use. After firing the Oreshnik, Kremlin spokesman Dmitry Peskov warned Britain and America of their 'reckless' action in supplying the long-range missiles to Ukraine. Peskov said: 'The main message is that the reckless decisions and actions of Western countries that produce missiles, supply them to Ukraine, and subsequently participate in strikes on Russian territory cannot remain without a reaction from the Russian side.' Putin also boasted that no country in the world has the power to intercept the Oreshnik missiles, which fly at ten times the speed of sound. Footage captured the moment the debris from the missile was located in Ukraine Ukrainian experts study their debris to gain insight into Russian military supply chains, production, and how to develop counter-measures Ukrainian President Volodymyr Zelensky has called the use of the weapon, which is capable of carrying multiple nuclear warheads, a severe escalation and urged his allies to respond The moment Russia used the Oreshnik for the first time to strike Dnipro, on November 21 A view shows a site of a Russian missile strike, amid Russia's attack on Ukraine, in Dnipro Firefighters work at the site of a Russian missile strike in Dnipro Putin boasted that no country in the world has the power to intercept the Oreshnik missiles, which fly at ten times the speed of sound He said: 'There is no countermeasure to such a missile, no means of intercepting it in the world today. 'And I will emphasise once again that we will continue testing this newest system. It is necessary to establish serial production.' He added: 'No one in the world has such weapons. Sooner or later other leading countries will also get them. We are aware that they are under development.' The missile being fired into Ukraine led the country's parliament to cancel a session, as security in Kiyv was tightened. Read More Putin's new missile leaves the whole of Europe minutes from Armageddon NATO chiefs and Ukrainian leaders are expected to hold emergency talks on Tuesday. But the West stood defiant against Putin last night, as France's foreign minister, Jean-Noël Barrot, gave Ukraine the green light to fire French long-range missiles into Russia 'in the logics of self-defence'. Last night, a senior Ukrainian military source said that the country had lost 40 per cent of the territory it had gained in Russia's Kursk region. The source said Russia had deployed 59,000 troops there, pushing Ukrainian troops back. He said: 'At most, we controlled about 531 square miles. Now we control approximately 309 miles.' President Zelensky revealed yesterday that Russian drone and missile attacks had damaged 321 Ukrainian port facilities since July last year. He added that 20 merchant ships belonging to other countries had also been damaged by Russian strikes. He said: 'Ukrainian food exports provide food for 400 million people in 100 countries around the world. Food prices in Egypt, Libya, Nigeria and other countries in Africa directly depend on whether farmers and agricultural companies in Ukraine can operate normally.' Russia Vladimir Putin Ukraine Share or comment on this article: Charred remains of Vladimir Putin's 8,370mph hypersonic Oreshnik missile retrieved by Ukraine after despot's boasts that 'no one in the world has such weapons' e-mail Add comment

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