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The 2024 XGP lineup stands as a shining example of the industry's creativity and talent, showcasing the best that gaming has to offer and setting a high standard for future releases to aspire to.As part of a national “moonshot” to cure blindness, researchers at the CU Anschutz Medical Campus will receive as much as $46 million in federal funding over the next five years to pursue a first-of-its-kind full eye transplantation. “This is no easy undertaking, but I believe we can achieve this together,” said Dr. Kia Washington, the lead researcher for the University of Colorado-led team, during a press conference Monday. “And in fact I’ve never been more hopeful that a cure for blindness is within reach.” The CU team was one of four in the United States that received funding awards from the federal Advanced Research Projects Agency for Health , or ARPA-H. The CU-based group will focus on achieving the first-ever vision-restoring eye transplant by using “novel stem cell and bioelectronic technologies,” according to a news release announcing the funding. The work will be interdisciplinary, Washington and others said, and will link together researchers at institutions across the country. The four teams that received the funding will work alongside each other on distinct approaches, though officials said the teams would likely collaborate and eventually may merge depending on which research avenues show the most promise toward achieving the ultimate goal of transplanting an eye and curing blindness. Dr. Calvin Roberts, who will oversee the broader project for ARPA-H, said the agency wanted to take multiple “shots on goal” to ensure progress. “In the broader picture, achieving this would be probably the most monumental task in medicine within the last several decades,” said Dr. Daniel Pelaez of the University of Miami’s Bascom Palmer Eye Institute, which also received ARPA-H funding. Pelaez is the lead investigator for that team, which has pursued new procedures to successfully remove and preserve eyes from donors, amid other research. He told The Denver Post that only four organ systems have not been successfully transplanted: the inner ear, the brain, the spinal cord and the eye. All four are part of the central nervous system, which does not repair itself when damaged. If researchers can successfully transplant the human eye and restore vision to the patient, it might help unlock deeper discoveries about repairing damage to the brain and spine, Pelaez said, as well as addressing hearing loss. To succeed, researchers must successfully remove and preserve eyes from donors and then successfully connect and repair the optical nerve, which takes information from the eye and tells the brain what the eye sees. A team at New York University performed a full eye transplant on a human patient in November 2023, though the procedure — while a “remarkable achievement,” Pelaez said — did not restore the patient’s vision. It was also part of a partial face transplant; other approaches pursued via the ARPA-H funding will involve eye-specific transplants. Washington, the lead CU researcher, said she and her colleagues have already completed the eye transplant procedure — albeit without vision restoration — in rats. The CU team will next work on large animals to advance “optic nerve regenerative strategies,” the school said, as well as to study immunosuppression, which is critical to ensuring that patients’ immune systems don’t reject a donated organ. The goal is to eventually advance to human trials. Pelaez and his colleagues have completed their eye-removal procedure in cadavers, he said, and they’ve also studied regeneration in several animals that are capable of regenerating parts of their eyes, like salamanders or zebra fish. His team’s funding will focus in part on a life-support machine for the eye to keep it healthy and viable during the removal process. InGel Therapeutics, a Massachusetts-based Harvard spinoff and the lead of a third team, will pursue research on 3-D printed technology and “micro-tunneled scaffolds” that carry certain types of stem cells as part of a focus on optical nerve regeneration and repair, ARPA-H said. ARPH-A, created two years ago, will oversee the teams’ work. Researchers at 52 institutions nationwide will also contribute to the teams. The CU-led group will include researchers from the University of Southern California, the University of Wisconsin, Indiana University and Johns Hopkins University, as well as from the National Eye Institute . The teams will simultaneously compete and collaborate: Pelaez said his team has communicated with researchers at CU and at Stanford, another award recipient, about their eye-removal research. The total funding available for the teams is $125 million, ARPA-H officials said Monday, and it will be distributed in phases, in part dependent on teams’ success. U.S. Rep. Diana DeGette, a Democrat who represents Denver in Congress, acknowledged the recent election results at the press conference Monday and pledged to continue fighting to preserve ARPA-H’s funding under President-elect Donald Trump’s administration. The effort to cure blindness, Washington joked, was “biblical” in its enormity — a reference to the Bible story in which Jesus cures a blind man. She and others also likened it to a moonshot, meaning the effort to successfully put Neil Armstrong and Buzz Aldrin on the moon nearly 50 years ago. If curing blindness is similar to landing on the moon, then the space shuttle has already left the launchpad, Washington said. “We have launched,” she said, “and we are on our trajectory.”At least 21 individuals were killed on Wednesday following an Israeli strike on a tent camp in Gaza, a Palestinian health official said. The Strike Atif Al-Hout, director of Nasser Hospital in Khan Younis, reported that in addition to the fatalities, the strike left at least 28 people injured. The Israeli military stated that its aircraft targeted senior Hamas militants in the area, describing them as being "involved in terrorist activities." According to the military, the strike triggered secondary explosions, suggesting the presence of explosives at the site. Independent verification of these claims was not immediately possible, and it is also possible that the blast ignited fuel, cooking gas canisters or other materials within the camp. Nasser Hospital received at least 15 bodies following the strike but determining an exact count was challenging due to the condition of the victims, many of whom were dismembered, severely burned or decapitated. The strike targeted the Muwasi area, a densely populated coastal camp sheltering hundreds of thousands of displaced people near Khan Younis in southern Gaza. It followed earlier Israeli airstrikes across the Palestinian enclave, including one in central Gaza that killed eight people, four of them children. Israel War in Gaza The war in Gaza erupted after Hamas-led militants launched a deadly attack on southern Israel on October 7, 2023, killing approximately 1,200 people, the majority of them civilians, and abducting around 250 individuals. Of those taken hostage, around 100 remain in Gaza, with estimates suggesting that at least a third of them are presumed dead. Israel's military campaign in Gaza has resulted in over 44,500 Palestinian deaths, primarily women and children, according to the Gaza Health Ministry. The ministry has not specified how many of the deceased were combatants. Meanwhile, the Israeli military claims it has killed more than 17,000 Hamas militants, though it has not provided evidence to substantiate those figures. Israel maintains that it aims to minimize civilian casualties and places responsibility for their deaths on Hamas. According to Israeli officials, the militant group frequently operates from within residential areas, using homes, schools, mosques and other civilian structures to conceal tunnels, rocket launchers and military infrastructure. Trump's Stance on the Gaza War After winning the 2024 presidential election, President-elect Donald Trump has spoken about the ongoing war in Gaza. Earlier this week, Trump issued a fiery demand for the release of hostages held by the Palestinian militant group before he came to office. Trump warned in a post to his Truth Social platform on Monday that "there will be ALL HELL TO PAY in the Middle East, and for those in charge who perpetrated these atrocities against Humanity" if the remaining captives seized by Hamas during their attack on Israel in October of last year were not freed before his January 20 inauguration. This article includes reporting from The Associated Press.
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In conclusion, Huang Yaqiong's philosophy of "Just Go for It" encapsulates the essence of a determined and grateful heart, ready to conquer any challenge that comes its way. Through her unwavering spirit and positive mindset, Huang serves as an inspiration to all, encouraging them to embrace gratitude, overcome obstacles, and reach for their dreams with unwavering determination.Canada shares higher at close of trade; S&P/TSX Composite up 0.15%
The English Premier League title race this season has been nothing short of thrilling, with four teams emerging as serious contenders for the coveted trophy. However, one team that has firmly established itself as a frontrunner in this intense competition is none other than Manchester City.
Through this innovative collaboration, users of Gaode Map can now easily locate and connect with Lenovo Baiying's network of certified technicians directly from the Gaode Map app. Whether you're experiencing hardware issues, software glitches, or simply need advice on optimizing your computer's performance, the one-click access feature allows you to quickly book an appointment with a Lenovo Baiying technician at a convenient location and time.Despite the whimsical nature of these myths, they have gained traction on social media and have fueled further speculation about the true intentions behind the Pepsi Coke collaboration. Some netizens have expressed concerns about potential changes to their favorite beverages, while others have voiced their support for the collaboration, hoping that it will lead to exciting new flavors and products.
DATA BREACH ALERT: Edelson Lechtzin LLP Is Investigating Claims On Behalf Of Bojangles Restaurants, Inc. Customers Whose Data May Have Been Compromised NEWTOWN, Pa., Nov. 22, 2024 (GLOBE NEWSWIRE) -- The law firm of Edelson Lechtzin LLP is investigating claims regarding data privacy violations by Bojangles Restaurants, Inc. (“Bojangles”). Bojangles learned of suspicious activity on or about March 12, 2024. To join this case, go HERE . About Bojangles Restaurants, Inc. Bojangles, founded in 1977 in Charlotte, North Carolina, is a restaurant chain known for its Southern-inspired menu made from scratch. Highlights include seasoned chicken, buttermilk biscuits, and classic sides like Dirty Rice and Cajun Pintos. Offering breakfast all day, Bojangles has expanded to around 800 locations across the Southeast. What happened? On or about March 12, 2024, Bojangles discovered unusual activity within its network. They initiated an investigation with the help of third-party cybersecurity experts to assess the situation. The investigation revealed that an unauthorized party accessed and downloaded specific files between February 19 and March 12, 2024. These files potentially contained sensitive personal information, including names, Social Security numbers, government-issued identification numbers, financial account or payment card details, biometric data, genetic information, and health or wellness records. Bojangles began mailing data breach notification letters to affected individuals on November 19, 2024. How can I protect my personal data? If you receive a data breach notification, you must guard against possible misuse of your personal information, including identity theft and fraud, by regularly reviewing your account statements and monitoring your credit reports for suspicious or unauthorized activity. Additionally, you should consider legal options for mitigating such risks. Edelson Lechtzin LLP is investigating a class action lawsuit to seek legal remedies for customers who may have had their sensitive personal and patient data compromised by the Bojangles data breach. For more information, please contact: Marc H. Edelson, Esq. EDELSON LECHTZIN LLP 411 S. State Street, Suite N-300 Newtown, PA 18940 Phone: 844-696-7492 Email: medelson@edelson-law.com Web: www.edelson-law.com About Edelson Lechtzin LLP Edelson Lechtzin LLP is a national class action law firm with offices in Pennsylvania and California. In addition to cases involving data breaches, our lawyers focus on class and collective litigation in cases alleging securities and investment fraud, violations of the federal antitrust laws, employee benefit plans under ERISA, wage theft and unpaid overtime, consumer fraud, and dangerous and defective drugs and medical devices. This press release may be considered Attorney Advertising in some jurisdictions. No class has been certified in this case, so counsel does not represent you unless you retain one. You may select counsel of your choice. You may also remain an absent class member and do nothing now. Your ability to share in any potential future recovery does not depend on serving as lead plaintiff.The death of Pier Paolo Pasolini still haunts me so
In conclusion, Wang Chun Qin's statement regarding the Hawk-Eye system and fair play in esports reflects his dedication to the game and his belief in the principles of sportsmanship. The ongoing debate over the system serves as a reminder of the importance of maintaining fairness and integrity in esports competitions. As the industry continues to evolve and grow, it is essential for players, officials, and spectators to work together to ensure that esports remains a competitive and respected sport.
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Pete Davidson's fame reached new heights after joining the cast of Saturday Night Live , but he claims that his pockets didn't get much bigger. The 31-year-old appeared in a New York Magazine Instagram Reel posted on Wednesday, December 4, in which he was asked, "What was your biggest splurge after your first 'SNL' paycheck?" The comedian repeated the question and then replied, "It's like three grand an episode." He later answered the original question about how he spent his first SNL paycheck, saying, "I think I got dinner." Fans of the NBC sketch comedy show took to Reddit to share their thoughts on the pay Davidson received. "$3,000 per episode seems way too low. Even 10 years ago you couldn't afford to independently live in Manhattan on 60K a year. Even 10 years ago you're paying like $40K a year in rent for a one-bed," wrote one fan. A second added, "Outside of Lorne and the senior staff, nobody's getting rich off of SNL. But if you play your cards right, you're getting rich AFTER SNL." Meanwhile, a third noted, "Pretty sure I've read somewhere it's just over 100k per year for newer cast. Which in NYC isn't a ton. Like you're not poor, but you're certainly not rich." Saturday Night Live has an average of 18 to 22 episodes per season, with one season per fiscal year. This means that if Davidson's numbers are correct, cast members appearing in every episode earn an average of $54,000 to $66,000, depending on the episode count. Davidson joined the cast of SNL in 2014 and stayed on for eight seasons before retiring in 2022. The comedian most recently made headlines after reports emerged in late November that he had checked into a rehabilitation center in Florida. All claims were dispelled when he was spotted at a Brooklyn Nets game with his mom after the rumors had spread.In conclusion, the 82nd Golden Globe Awards nominations have set the stage for an exciting and competitive ceremony, with three individuals receiving dual nominations and streaming platform Netflix poised to emerge as a major winner. As the entertainment industry gears up for the prestigious event, the Golden Globe Awards promise to honor and celebrate the exceptional talent and creativity that continue to captivate audiences around the world.
As Dragon Flame spoke about the victorious match and the upcoming challenges on the horizon, a sense of determination and passion infused every word. "The path to success is paved with hard work, dedication, and an unwavering commitment to excellence," Dragon Flame declared. "I am ready to embrace the journey ahead, to learn from every experience, and to emerge as a stronger, more formidable competitor."
In a shocking turn of events, a chief prosecutor in Heilongjiang was recently caught soliciting prostitution. The news has sent ripples through the legal community and raised questions about ethics and integrity within the justice system.