MIAMI GARDENS, Fla. (AP) — Dolphins coach Mike McDaniel said he was caught off guard by reports early Tuesday that linebacker Shaq Barrett wants to unretire. The two-time Super Bowl winner signed a one-year deal with the Dolphins in March, then abruptly announced his retirement on social media in July, just days before the start of Miami's training camp. “Just to be candid, obviously there's a reason why you target and sign somebody," McDaniel said Tuesday afternoon. “I was fully caught off guard, or caught by surprise this morning as I found out.” McDaniel indicated the Dolphins have not had any conversations with Barrett recently. Miami holds the 32-year-old’s contractual rights. ESPN first reported the news. “It was kind of news as you guys got it,” McDaniel said. He also said he hasn't had a chance to think about Barrett potentially rejoining the team, and that his immediate focus is on Miami's Thursday night game at Green Bay. “The team is counting on me to think about the Packers,” he said. "I'll get with (GM) Chris (Grier), and we'll work through that. There's a ton of implications that go along with it in terms of team and roster stuff, so we'll work through that as we just got the news today.” Barrett has 400 tackles, 59 sacks, 22 forced fumbles and three interceptions in nine seasons — four with Denver and five with Tampa Bay. He was a second-team All-Pro with the Buccaneers in 2019, with a league-high 19 1/2 sacks. The Dolphins waived veteran safety Marcus Maye on Tuesday and activated rookie safety Patrick McMorris from injured reserve. Maye, who signed with the Dolphins in June, played in 11 games with three starts for Miami this season. He had 30 tackles and a tackle for loss. He could re-sign to the team's practice squad if he clears waivers. Maye previously played for New Orleans, but was cut in a money-saving move in March after two seasons with the Saints. Maye's release made room on the roster for McMorris, who was drafted in the sixth round by Miami in April. He began the season on injured reserve because of a calf injury. AP NFL: https://apnews.com/hub/nflCanada stocks lower at close of trade; S&P/TSX Composite down 0.02%
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Education The free and compulsory primary education has been focused in each successive government’s education policy, but the programme was never implemented in letter and spirit. Resultantly, goals set under SDGs, particularly those relating to primary education for all, remained low by great margin from the target. Resultantly, Pakistan is faced with the lowest literacy rate and a glaring inequality in education gender wise. According to recent Human Development report, published by UNDP, regarding gender gap, Pakistan has been placed at 145th position out of 146 countries surveyed. Only 27.9 percent of females of the age 15 and above are literate. As per statics of 2022, there were 80 percent and 55 percent literacy rates in urban and rural areas, respectively, of the country. In rural areas, female enrolment rate is around 42 percent. Female enrolment was recorded highest at primary level, but seems to decrease progressively at secondary, college and tertiary levels. Keeping in view the size of the social sector development programme, there is a need to increase allocations for education and health sectors. The present allocation for education, being 2.7 percent of GNP or 8.8 percent of total government expenditures, is woefully low. Status of women development in Pakistan–I However, it is a matter of satisfaction that new education policy has its focus on technical education, particularly on information technology for women. In recent years, non-governmental sector’s role has gained a lot of importance in developing and implementing social sector initiatives. Donor agencies and government itself have inducted notable NGOs for promoting female education in less-developed areas of all the four provinces speedily, realizing the fact that education besides having its intrinsic worth has impact on human capital, productivity and capabilities for participation and social interaction. Economic empowerment According to Human Development report of 2022, population earning dollars two or less per day exceeds 84% of the total population. Nearly 70 percent of this poverty-stricken population of Pakistan is women. In order to eradicate poverty and empower women economically, their participation in economic process needs to be enhanced. In recent years there has been substantial increase in urban women participation in economic activity due to increase in the number of educated women, rising cost of living and successive governments’ objective of mainstreaming women in economic process. Despite increasing involvement of women in economic activity, there is wide gender gap regarding size of earnings. The human development report depicts a woman’s earnings equivalent to US dollar 916 against 2,884 of man. The report also reveals that employment of women in Agriculture is 66 percent of total female population, whereas male employment ratio in agriculture is only 41 percent. Females’ average contribution to total family income has improved to 39 percent. This is mainly due to increasing responsibilities imposed on women to maintain not only themselves, but also their rapidly growing families. Resultantly, their deployment in informal sector continues to increase. Women’s share in formal sector, particularly in civil and financial services, has enhanced considerably. In NPS grades 16 to 22 their percentage has improved to 11 percent, whereas in lower scales it continues to be 5 percent for last 10 years. In financial sector, women employees’ strength has got doubled in last 10 years and women have been provided opportunities to elevate themselves to clinch top and senior management positions. Actual need is to look into plight of women in informal sector where legal and economic rights are being denied due to lacunae in labor laws relating to the fields where most women work. Hence informal sector is needed to be documented, making registration of each employee of business units compulsory irrespective of its size to remove all exploitations of workers. The reserved quota for women in all civil services and public sector corporations needs to be enhanced to 20% at least and to be monitored strictly. Government’s initiatives to motivate women to become self–employed deserve appreciation. Women have been given easy access to credit through specialized financial institutions like First Women Bank and SME Bank and also Micro Credit Banks both in public and private sectors. The recent involvement of Export Promotion Bureau and Chambers of Commerce and Industry to improve business and technical skills of businesswomen is really commendable. Creation of separate chambers of trade and commerce is yet another advantageous step to promote businesses of women. They organize seminars and technical courses on continuous basis for the purpose, and to create market for their products, exhibitions are being held both abroad and within the country. This will go a long way in motivating women to set up businesses not only for their own economic well-being, but also for the country’s overall economic development. Further, historically, women now have the largest-ever representation in Assemblies, Senate and Local governments. They will have parliamentary strength to influence legislative processes for reviewing all discriminatory laws against women and also to prevail upon economic managers of the country to make greater allocations for social sector and women development in particular. (Concluded) Copyright Business Recorder, 2024Sean ’Diddy’ Combs’ third bid to be released on bail won’t be decided until next weekNone
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The for ( ) stock moved into a higher percentile Monday, as it got a lift from 67 to 75. This exclusive rating from Investor's Business Daily tracks market leadership with a 1 (worst) to 99 (best) score. The score shows how a stock's price behavior over the last 52 weeks stacks up against all the other stocks in our database. Decades of market research reveals that the market's biggest winners typically have an RS Rating north of 80 in the early stages of their moves. See if Unity Software stock can continue to show renewed price strength and hit that benchmark. Is Unity Software Stock A Buy? Unity Software stock is still inside a buy zone after breaking past a 23.40 buy point in a . The proper buying range is up to 5% above the initial entry. Once a stock moves above that range, it's best to wait for it to set up another buying opportunity.. The video game engine developer reported 0% EPS growth last quarter, while sales growth came in at -18%. Unity Software stock earns the No. 11 rank among its peers in the Computer Software-Design industry group. ( ), ( ) and ( ) are among the top 5 highly rated stocks within the group.FOOTBALL Azeez Al-Shaair of the Houston Texans took to X on Monday morning to apologize to Trevor Lawrence of the Jacksonville Jaguars after his violent blow to the quarterback’s facemask led to Lawrence being carted off the field with a concussion. Back in the starting lineup after missing two games with a sprained left shoulder, Lawrence scrambled left on a second-and-7 play in the second quarter of Houston’s 23-20 win Sunday. He initiated a slide before Al-Shaair raised his forearm and unleashed on the defenseless quarterback. In the long post , Al-Shaair, who was ejected for the hit, first said he didn’t see Lawrence sliding until “it was too late” and that it happened “in the blink of an eye” before saying he was sorry. “To Trevor I genuinely apologize to you for what ended up happening,” Al-Shaair wrote. “Before the game we spoke and I told you how great it was to see you back out on the field and wished you well. I would never want to see any player hurt because of a hit I put on them, especially one that was ruled ‘late’ or ‘unnecessary.’ ” • Hall of Fame wide receiver Randy Moss, 47, revealed he’s dealing with a health issue and asked fans to pray for him and his family. In an announcement on Instagram, Moss directed urged men to get checkups and bloodwork done, without specifying for any particular illness. • Aaron Rodgers will remain the New York Jets’ starting quarterback despite speculation he could be benched in what has been a disappointing season. FIGURE SKATING GRAND PRIX: World pairs champions Deanna Stellato-Dudek and Maxime Deschamps of Canada withdrew from the Grand Prix final at Grenoble, France, because Deschamps is recovering from an illness and unable to compete. Rebecca Ghilardi and Filippo Ambrosini of Italy will replace them. The competition begins Thursday with the pairs short program, and medals will be decided after the pairs free skate Friday night. BASKETBALL WNBA: An expanded WNBA with more games and a new franchise will tip off May 16. The league extended its schedule to 44 games this year, up from 40, with the addition of the expansion Golden State Valkyries . The new team, which has over 20,000 season ticket deposits, will play its inaugural game at home on opening night against Los Angeles. The Indiana Fever will host the league’s All-Star Game on July 19. GOLF LPGA: Mollie Marcoux Samaan is resigning in January as commissioner, a surprise announcement after record growth in prize money along with criticism the LPGA wasn’t gaining in popularity during the surge in women’s sports. Marcoux Samaan will leave Jan. 9, three weeks before the LPGA begins its 75th season. Liz Moore, the chief legal and technology officer, will be interim commissioner until a search committee hires a new one. BASEBALL HALL OF FAME: Hall of Fame players Paul Molitor, Eddie Murray, Tony Pérez, Lee Smith and Ozzie Smith are among 16 members of the classic era committee that will consider an eight-man Hall ballot that includes Dick Allen, Dave Parker and Luis Tiant. The ballot also includes Tommy John, Steve Garvey and Ken Boyer, and former Negro Leaguers John Donaldson and Vic Harris. The classic era committee considers players, managers, umpires and executives whose greatest contributions to the sport were before 1980. • The Chicago Cubs added Matthew Boyd to their rotation in their first big offseason move, agreeing to a $29 million, two-year contract with the veteran left-hander, who made a successful return from Tommy John surgery, going 2-2 with a 2.72 ERA in eight starts with Cleveland this year. TENNIS DAVIS CUP: The Davis Cup Final 8 will be held in Italy from 2025 through 2027, the International Tennis Federation announced, with Bologna hosting next year. Led by Jannik Sinner , the Italians won the past two Davis Cup titles in Malaga, Spain, the site for the men’s team competition each of the past three years. — News service reports We invite you to add your comments. We encourage a thoughtful exchange of ideas and information on this website. By joining the conversation, you are agreeing to our commenting policy and terms of use . 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MIAMI GARDENS, Fla. (AP) — Dolphins coach Mike McDaniel said he was caught off guard by reports early Tuesday that linebacker Shaq Barrett wants to unretire. The two-time Super Bowl winner signed a one-year deal with the Dolphins in March, then abruptly announced his retirement on social media in July, just days before the start of Miami's training camp. “Just to be candid, obviously there's a reason why you target and sign somebody," McDaniel said Tuesday afternoon. “I was fully caught off guard, or caught by surprise this morning as I found out.” McDaniel indicated the Dolphins have not had any conversations with Barrett recently. Miami holds the 32-year-old’s contractual rights. ESPN first reported the news. “It was kind of news as you guys got it,” McDaniel said. He also said he hasn't had a chance to think about Barrett potentially rejoining the team, and that his immediate focus is on Miami's Thursday night game at Green Bay. “The team is counting on me to think about the Packers,” he said. "I'll get with (GM) Chris (Grier), and we'll work through that. There's a ton of implications that go along with it in terms of team and roster stuff, so we'll work through that as we just got the news today.” Barrett has 400 tackles, 59 sacks, 22 forced fumbles and three interceptions in nine seasons — four with Denver and five with Tampa Bay. He was a second-team All-Pro with the Buccaneers in 2019, with a league-high 19 1/2 sacks. The Dolphins waived veteran safety Marcus Maye on Tuesday and activated rookie safety Patrick McMorris from injured reserve. Maye, who signed with the Dolphins in June, played in 11 games with three starts for Miami this season. He had 30 tackles and a tackle for loss. He could re-sign to the team's practice squad if he clears waivers. Maye previously played for New Orleans, but was cut in a money-saving move in March after two seasons with the Saints. Maye's release made room on the roster for McMorris, who was drafted in the sixth round by Miami in April. He began the season on injured reserve because of a calf injury. AP NFL: https://apnews.com/hub/nfl
HUNTSVILLE, Dec. 02, 2024 (GLOBE NEWSWIRE) -- Serina Therapeutics, Inc. (“Serina”) (NYSE American: SER), a clinical-stage biotechnology company, today announced a $10 million equity financing with strategic shareholder JuvVentures (UK) Limited. The transaction provides Serina with funding to continue advancing SER-252 (POZ-apomorphine), enabled by its proprietary POZ Platform TM drug optimization technology, into a Phase 1 clinical trial in advanced Parkinson's disease patients in the second half of 2025. Under the terms of the funding agreement, Serina will issue one million shares of common stock at $10 per share, a 120% premium to the closing price on November 26, 2024. The financing will be delivered in two tranches: the first $5.0 million tranche was received November 27, 2024, and the second $5.0 million tranche by January 31, 2025. Serina filed a Form 8-K with the SEC on December 2, 2024 that provides additional information regarding this transaction. About SER-252 (POZ-apomorphine) SER 252 is an investigational apomorphine therapy developed with Serina’s POZ platform and designed to provide continuous dopaminergic stimulation (CDS). CDS has been shown to reduce the severity of levodopa-related motor complications (dyskinesia) and enable greater on time, with reduced off time, in advanced Parkinson’s patients. SER-252 leverages strategic partner Enable Injections’ enFuse TM wearable drug delivery platform to enhance patient comfort and convenience, providing CDS to patients via an easy-to-administer, long-acting subcutaneous injection without skin reactions. About the POZ Platform TM Serina’s proprietary POZ technology is based on a synthetic, water soluble, low viscosity polymer called poly(2-oxazoline). Serina’s POZ technology is engineered to provide greater control in drug loading and more precision in the rate of release of attached drugs delivered via subcutaneous injection. The therapeutic agents in Serina’s product candidates are typically well-understood and marketed drugs that are effective but are limited by pharmacokinetic profiles that can include toxicity, side effects and short half-life. Serina believes that by using POZ technology, drugs with narrow therapeutic windows can be designed to maintain more desirable and stable levels in the blood. Serina’s POZ platform delivery technology has potential for use across a broad range of payloads and indications. Serina intends to advance additional applications of the POZ platform via out-licensing, co-development, or other partnership arrangements, including the non-exclusive license agreement with Pfizer, Inc. to use Serina’s POZ polymer technology for use in lipid nanoparticle drug (LNP) delivery formulations. About Serina Therapeutics Serina is a clinical-stage biotechnology company developing a pipeline of wholly owned drug product candidates to treat neurological diseases and other indications. Serina’s POZ Platform TM provides the potential to improve the integrated efficacy and safety profile of multiple modalities including small molecules, RNA-based therapeutics and antibody-based drug conjugates (ADCs). Serina is headquartered in Huntsville, Alabama on the campus of the HudsonAlpha Institute of Biotechnology. For more information, please visit https://serinatherapeutics.com . Cautionary Statement Regarding Forward-Looking Statement This release contains forward-looking statements within the meaning of federal securities laws. These statements are based on management’s current expectations, plans, beliefs or forecasts for the future, and are subject to uncertainty and changes in circumstances. Any express or implied statements in this press release that are not statements of historical fact, including statements about the potential of Serina’s POZ polymer technology, are forward-looking statements that involve substantial risks and uncertainties that could cause actual results to differ materially from those expressed or implied by such statements. Risks and uncertainties include, among other things, the uncertainties inherent in research and development, including the ability to meet anticipated clinical endpoints, commencement and/or completion dates for clinical trials, regulatory submission dates, regulatory approval dates and/or launch dates, as well as the possibility of unfavorable new clinical data and further analyses of existing clinical data; the risk that clinical trial data are subject to differing interpretations and assessments by regulatory authorities; whether regulatory authorities will be satisfied with the design of and results from our clinical studies; whether and when any applications may be filed for any drug or vaccine candidates in any jurisdictions; whether and when regulatory authorities may approve any potential applications that may be filed for any drug or vaccine candidates in any jurisdictions, which will depend on a myriad of factors, including making a determination as to whether the product’s benefits outweigh its known risks and determination of the product’s efficacy and, if approved, whether any such drug or vaccine candidates will be commercially successful; decisions by regulatory authorities impacting labeling, manufacturing processes, safety and/or other matters that could affect the availability or commercial potential of any drug or vaccine candidates; and competitive developments. These risks as well as other risks are more fully discussed in the company’s Annual Report on Form 10-K for the year ended December 31, 2023, the company’s Current Report on Form 8-K that was filed with the SEC on April 1, 2024, and the company’s other periodic reports and documents filed from time to time with the SEC. The information contained in this release is as of the date hereof, and Serina assumes no obligation to update forward-looking statements contained in this release as the result of new information or future events or developments. For inquiries, please contact: Investor.relations@serinatherapeutics.com (256) 327-9630
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