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House rejects Democratic efforts to force release of Matt Gaetz ethics reportOutlook Therapeutics ( NASDAQ:OTLK – Get Free Report ) posted its earnings results on Friday. The company reported ($0.77) EPS for the quarter, beating analysts’ consensus estimates of ($0.83) by $0.06, Zacks reports. Outlook Therapeutics Stock Performance NASDAQ OTLK opened at $2.01 on Friday. The firm’s fifty day moving average is $3.81 and its two-hundred day moving average is $5.90. The firm has a market cap of $47.55 million, a PE ratio of -0.19 and a beta of 0.46. Outlook Therapeutics has a one year low of $0.87 and a one year high of $12.85. Wall Street Analyst Weigh In OTLK has been the topic of a number of research analyst reports. HC Wainwright reissued a “buy” rating and issued a $30.00 target price on shares of Outlook Therapeutics in a research report on Friday, November 29th. Ascendiant Capital Markets decreased their price objective on Outlook Therapeutics from $35.00 to $33.00 and set a “buy” rating for the company in a research note on Tuesday, September 3rd. Chardan Capital restated a “neutral” rating on shares of Outlook Therapeutics in a research note on Monday, December 2nd. Finally, BTIG Research lowered their price target on shares of Outlook Therapeutics from $50.00 to $9.00 and set a “buy” rating for the company in a report on Friday, November 29th. One equities research analyst has rated the stock with a hold rating and six have given a buy rating to the company. Based on data from MarketBeat.com, the company presently has an average rating of “Moderate Buy” and an average target price of $32.73. Outlook Therapeutics Company Profile ( Get Free Report ) Outlook Therapeutics, Inc, operates as a clinical-stage biopharmaceutical company, focuses on developing and commercializing monoclonal antibodies for various ophthalmic indications. Its lead product candidate is ONS-5010, an ophthalmic formulation of bevacizumab product candidate that is in Phase-III clinical trial for the treatment of wet age-related macular degeneration and other retina diseases. Recommended Stories Receive News & Ratings for Outlook Therapeutics Daily - Enter your email address below to receive a concise daily summary of the latest news and analysts' ratings for Outlook Therapeutics and related companies with MarketBeat.com's FREE daily email newsletter .
Groundbreaking Directive Ensures ALS Patients on Medicare Advantage Gain Access to QalsodyThe local Cook Islands community’s sincere welcome, music, drumming and refreshments were very much appreciated. Unfortunately, the consultation had its fair share of logistical hiccups, with an event originally advertised to be from 5pm – 8pm, ending up being 6.45pm to well after 11pm. The unexpected change to the start time, the Prime Minister’s late arrival (due to peak hour traffic) and drawn-out schedule tested patience, with at least half (if not more) of the attendees leaving before the end of the presentation. It’s tough when a meeting meant to engage and inform, ends up being a test of endurance. My son, Jonny, noted that the Prime Minister’s three pillars (church, government, traditional leaders) pretty much said the same thing; i.e. we need to diversify, get rich, have new job opportunities, and assist the transition to clean energy. However, we don’t have enough locals to fill jobs already and people are finding other ways to diversify in business and career paths. As for the clean energy transition – if life is lost and ecosystems destroyed, can anyone claim this is clean energy? The PM Mark Brown mentioned that technology is advancing, so the metals may not be needed in the future, which is why he wants to harvest the nodules while they’re still valuable. In Maori, he concluded that we can choose to take this opportunity... or miss out. This FOMO (fear of missing out) thinking causes panic, less care and patience for the research process, and collaborative consultation over the results. Recently I was at a Blue Planet Alliance (BPA) forum with Government representatives. BPA’s aim is 100 per cent clean energy (for electricity) by 2045. They made it clear that they do not believe Deep Sea Mining (DSM) is needed for the clean energy transition. My son found the science portion interesting, but when Te Ipukarea’s director was mentioned, he jumped up to question why John Parianos of Cook Islands Seabed Minerals Authority hadn’t reflected TIS’s stance against DSM in his talk. John replied that TIS is not against DSM, but for getting it done properly. The following excerpts from director Alanna Smith, speaking during the WISE expedition, I trust clarifies TIS’s position: “Supporting deep ocean research does not mean supporting deep sea mining. It is important to have trained observers onboard to ensure transparency, making sure that the data being collected is shared, but also ensuring that there is good science and good questions ... for example a mining company’s research could be sided towards mineral quality and where the nodules are most dense .... having little attention to what life is in these spaces ... To reiterate, participation on this expedition does not mean support for DSM.” The 45 minutes (approx.) Q&A had only one question relating to the environment. After seeing the slides and listening to a recording of the night, I would say this is because risks to the environment were just glanced over, not explained, so people still don’t know enough to form questions. My son posed a pointed question about environmental impact – One of the slides shows an approximation of the effect three operations over thirty years would have (approximately 1.2 per cent of the EEZ). Is there a reality where enough operations could, over one generation (30 years) destroy the entire EEZ? John Parianos replied that hypothetically yes, which is why we need to get things right to have only an acceptable level of damage (Paraphrased). Clearly both sides agree there will be long-term implications for ecosystems. As one attendee said, in Maori, at the end of the night ... fulfil your dream. If it works out well, it’s ours. If it turns bad, it’s yours. But it isn’t that simple, if for example, fish stocks are depleted because of linked ecosystems in the chain being destroyed, then everyone who relies on fish suffers. The recounting from family is not just a summary of events, but a reflection on the need for better planning, engagement, and transparency. When these ‘consultations’ are about such a significant and potentially life changing move, why have the NGOs not been included? It is at best a road show, at worst a propaganda tour, but without all parties present, it is not a consultation. E te au tangata Kuki Airani, akamanako o’onu. Consider what level of damage to our ocean is acceptable. Our answers will shape our future, our way of life and our Marae Moana.
Hegseth meets with moderate Sen. Collins as he lobbies for key votes in the SenatePlans Required to Cover Treatment for SOD1-ALS ARLINGTON, Va. , Dec. 11, 2024 /PRNewswire/ -- The Centers for Medicare & Medicaid Services (CMS) has announced a first-of-its-kind directive requiring Medicare Advantage plans to approve coverage for Qalsody, a treatment for people living with genetic SOD1-ALS. This decision reflects the ALS Association's commitment to ensuring that people living with ALS have access to promising ALS treatments without delay. "This is a victory for the entire ALS community," said Calaneet Balas, president and CEO of the ALS Association. "It's critical that FDA-approved treatments are made accessible rather than being labeled as 'experimental.' We are grateful to everyone in our community who helped make this day happen." Balas added: "We hope this sends a message to the entire rare disease community and pharmaceutical industry that new treatments can be developed and made accessible to those who will benefit from them. We need to ensure more ALS treatments are developed and approved that will help everyone living with ALS." The ALS Association played a key role in the historic CMS directive by participating and advocating for the research, approval, and accessibility of Qalsody for people living with ALS. In 2004, the ALS Association was the first to fund research into ALS-specific antisense oligonucleotide (ASO) technology, investing over $1.3 million in groundbreaking studies that laid the foundation for the development of Qalsody. This early commitment supported preclinical studies, safety trials, and the first-in-human phase 1 trial, which established SOD1 as a viable therapeutic target. In 2023, Qalsody became the first gene-based therapy approved for ALS , thanks in part to the ALS Association's efforts, including a united push from the ALS community for FDA accelerated approval. This new CMS directive provides precedent for state regulators to issue similar actions for other private insurers. According to the Valor study published in 2022 , Qalsody, which was developed specifically to target the RNA produced by mutated SOD1 genes, has demonstrated significant promise in clinical trials and real-world studies. In the phase 3 VALOR trial, Qalsody reduced levels of mutated SOD1 proteins in cerebral spinal fluid by 35% within eight weeks and decreased bloodstream levels of neurofilament light chain (NfL)—a key biomarker of neurodegeneration—by 50% within 12-16 weeks. These biological changes translated into measurable clinical benefits, including slower disease progression, improved respiratory function, and enhanced quality of life after 52 weeks of treatment. Real-world data has since validated these findings, with some patients stabilizing or even experiencing improvements in motor function and quality of life. When insurance companies began denying access to Qalsody, labeling it as "experimental," the ALS Association took decisive action, working directly with CMS to launch an investigation into these unjust denials. By presenting evidence of widespread insurance rejections and demonstrating the critical need for immediate intervention. In addition to working with CMS, the ALS Association actively engaged policymakers, held strategic meetings with state and federal legislators, and served as a staunch advocate for patients, ensuring their voices were heard and their rights to life-changing treatment were upheld. The ALS Association urges anyone previously denied Qalsody by their Medicare Advantage plan to contact their ALS specialist immediately to begin the process of securing access to this critical treatment. For more information on the CMS directive visit als.org About the ALS Association The ALS Association is the largest ALS organization in the world. The ALS Association funds global research collaborations, assists people with ALS and their families through its nationwide network of care and certified clinical care centers, and advocates for better public policies for people with ALS. The ALS Association is working to make ALS a livable disease while urgently searching for new treatments and a cure. For more information about the ALS Association, visit our website at www.als.org . About ALS Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord. Over the course of the disease, people lose the ability to move, to speak, and eventually, to breathe. The disease is always fatal, usually within five years of diagnosis. Few treatment options exist, resulting in a high unmet need for new therapies to address functional deficits and disease progression. View original content to download multimedia: https://www.prnewswire.com/news-releases/groundbreaking-directive-ensures-als-patients-on-medicare-advantage-gain-access-to-qalsody-302329525.html SOURCE The ALS AssociationBudget Blinds Announces Strategic Changes to Executive Leadership Team
O’Shea stands by decision to keep playing Collaros after QB was hurt in Grey CupConocoPhillips (NYSE: COP) today announced that it has completed its acquisition of Marathon Oil Corporation (NYSE: MRO). “This acquisition of Marathon Oil is a perfect fit for ConocoPhillips, adding to our deep, durable and diverse portfolio while meeting our strict financial framework,” said Ryan Lance, chairman and chief executive officer. “Marathon Oil adds high-quality, low cost of supply inventory adjacent to our leading U.S. unconventional position. We have a strong history of seamlessly integrating assets and we expect to deliver synergies of over $1 billion on a run rate basis in the next 12 months.” In accordance with the terms of the merger agreement, each share of Marathon Oil common stock was converted into the right to receive 0.255 shares of ConocoPhillips common stock at the effective time of the merger, with cash in lieu of fractional shares. Source: ConocoPhillips
The Size Of The Fluoropolymer Coating Market Is Projected To Reach $2.34 Billion By 2028, With A CAGR Of 5.2%