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2025-01-21
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PLEASANTON, Calif. , Dec. 23, 2024 /PRNewswire/ -- 10x Genomics, Inc. (Nasdaq: TXG), a leader in single cell and spatial biology, announced today it had secured a permanent injunction in the U.S. District Court for the District of Delaware against the GeoMx products sold by Bruker Corporation (Nasdaq: BRKR), which acquired the product line from NanoString Technologies. To minimize the risk of disruption to ongoing research, 10x Genomics requested a carve-out for GeoMx users who installed an instrument prior to the trial in November 2023 . The injunction, which the Court said it will enter in January 2025 , is expected to prohibit Bruker from making, using, selling or offering to sell in the United States its GeoMx Digital Spatial Profiler and associated instruments, reagents and services for RNA and protein detection. At the request of 10x Genomics, the injunction will not block ongoing research by researchers who installed a GeoMx instrument prior to November 18, 2023 . Such customers can continue to purchase GeoMx reagents for use with existing GeoMx instruments for purposes of continuing their ongoing research. The Court found that making such an exception for ongoing research strikes a "workable balance between protecting the patentee's rights and protecting the public from the injunction's adverse effects." In addition, the Court affirmed the $31 million damages awarded by the November 2023 jury verdict, as well as supplemental damages and interest that will be added to the total damages when final judgment is entered. "Today's decision helps to safeguard our decade-long investment in innovation and ensures we can continue to develop groundbreaking technologies that help our customers revolutionize science," said Eric Whitaker , Chief Legal Officer at 10x Genomics. "10x exists to fuel scientific progress – not stifle it – and that is why we've done our utmost to ensure this injunction was structured to protect both our intellectual property and existing GeoMx customers' ongoing research." The Court recognized the harm NanoString's infringing conduct caused 10x when it wrote in its ruling, "Having been careful not to license its technology, 10x suffers when it proclaims itself as an innovator in spatial genomics but a competitor is using the same innovative, patented technology." Today's Court decision follows a November 2023 jury verdict that found that NanoString's GeoMx products willfully infringed seven patents exclusively licensed to 10x Genomics by Prognosys. During the trial, the jury heard testimony from the sole inventor of the patents, Illumina co-founder Mark Chee , and NanoString CEO Brad Gray and NanoString CSO Joe Beechem. After hearing all of the evidence, the jury determined that all seven patents had been infringed by NanoString, that each patent was valid, that NanoString willfully infringed those patents and that monetary damages were owed to 10x for the infringement of all seven patents. In affirming the jury's finding that NanoString willfully infringed, the Court relied on the evidence showing that NanoString knew or was willfully blind that its acts would cause infringement of 10x's rights. The asserted patents in Case No. 21-cv-653-MFK include (a) U.S. Patent No. 10,472,669; (b) U.S. Patent No. 10,961,566; (c) U.S. Patent No. 10,983,113; (d) U.S. Patent No. 10,996,219; (e) U.S. Patent No. 11,001,878; (f) U.S. Patent No. 11,008,607 and (g) U.S. Patent No. 11,293,917. About 10x Genomics 10x Genomics is a life science technology company building products to accelerate the mastery of biology and advance human health. Our integrated solutions include instruments, consumables and software for single cell and spatial biology, which help academic and translational researchers and biopharmaceutical companies understand biological systems at a resolution and scale that matches the complexity of biology. Our products are behind breakthroughs in oncology, immunology, neuroscience and more, fueling powerful discoveries that are transforming the world's understanding of health and disease. To learn more, visit 10xgenomics.com or connect with us on LinkedIn or X (Twitter) . Forward Looking Statements This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 as contained in Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, which are subject to the "safe harbor" created by those sections. All statements included in this press release, other than statements of historical facts, may be forward-looking statements. Forward-looking statements generally can be identified by the use of forward-looking terminology such as "may," "might," "will," "should," "expect," "plan," "anticipate," "could," "intend," "target," "project," "contemplate," "believe," "see," "estimate," "predict," "potential," "would," "likely," "seek" or "continue" or the negatives of these terms or variations of them or similar terminology, but the absence of these words does not mean that a statement is not forward-looking. These forward-looking statements include statements regarding litigation and remedies as well as possible outcomes of litigation. These forward-looking statements do not reflect that our success will depend on our ability to obtain, maintain and protect our intellectual property rights, intellectual property litigation could be expensive, time-consuming, unsuccessful and could interfere with our ability to develop, manufacture and commercialize our products or technologies, litigation outcomes are unpredictable or there may be changes in our litigation strategy. These statements are based on management's current expectations, forecasts, beliefs, assumptions and information currently available to management. Actual outcomes and results could differ materially from these statements due to a number of factors and such statements should not be relied upon as representing 10x Genomics, Inc.'s views as of any date subsequent to the date of this press release. 10x Genomics, Inc. disclaims any obligation to update any forward-looking statements provided to reflect any change in 10x Genomics' expectations or any change in events, conditions or circumstances on which any such statement is based, except as required by law. The material risks and uncertainties that could affect 10x Genomics, Inc.'s financial and operating results and cause actual results to differ materially from those indicated by the forward-looking statements made in this press release include those discussed under the captions "Risk Factors" and "Management's Discussion and Analysis of Financial Condition and Results of Operations" in the company's most recently-filed 10-K for the fiscal year ended December 31, 2023 and elsewhere in the documents 10x Genomics, Inc. files with the Securities and Exchange Commission from time to time. Disclosure Information 10x Genomics uses filings with the Securities and Exchange Commission, our website ( www.10xgenomics.com ), press releases, public conference calls, public webcasts and our social media accounts as means of disclosing material non-public information and for complying with our disclosure obligations under Regulation FD. Contacts Investors: investors@10xgenomics.com Media: media@10xgenomics.com View original content to download multimedia: https://www.prnewswire.com/news-releases/us-district-court-awards-10x-genomics-permanent-injunction-in-patent-infringement-lawsuit-against-bruker-corporations-geomx-products-302338627.html SOURCE 10x Genomics, Inc.

Oncocyte dd-cfDNA Assay Detects Kidney Transplant Rejection 11+ Months Ahead of Standard Protocols, New Study AffirmsNone

Bengals optimistic heading into new month, meeting vs. SteelersAndrej Stojakovic made 11 free throws to help craft a team-high 20 points, freshman Jeremiah Wilkinson had his second consecutive big game off the bench and Cal ran its winning streak to three with an 83-77 nonconference victory over Sacramento State on Sunday afternoon in Berkeley, Calif. Wilkinson finished with 16 points and Rytis Petraitis 13 for the Golden Bears (5-1), whose only loss this season was at Vanderbilt. Jacob Holt went for a season-high 25 points for the Hornets (1-4), who dropped their fourth straight after a season-opening win over Cal State Maritime. Seeking a fourth straight home win, Cal led by as many as 12 points in the first half and 40-33 at halftime before Sacramento State rallied. The Hornets used a 14-5 burst out of the gate following the intermission to grab a 47-45 lead. Julian Vaughns had a 3-pointer and three-point play in the run. But Cal dominated pretty much the rest of the game, taking the lead for good on a Petraitis 3-pointer with 14:50 remaining. Stojakovic, a transfer from rival Stanford, went 11-for-15 at the foul line en route to his third 20-point game of the young season. Cal outscored Sacramento State 26-17 on free throws to more than account for the margin of victory. Coming off a 23-point explosion in his first extended action of the season, Wilkinson hit five of his 10 shots Sunday. The Golden Bears outshot the Hornets 47.2 percent to 43.1 percent. Joshua Ola-Joseph contributed 10 points and six rebounds, Mady Sissoko also had 10 points and Petraitis found time for a team-high five assists. Holt complemented his 25 points with a game-high eight rebounds. He made four 3-pointers, as did Vaughns en route to 18 points, helping Sacramento State outscore Cal 30-21 from beyond the arc. EJ Neal added 16 points for the Hornets, while Emil Skytta tied for game-high assist honors with five to go with seven points. --Field Level MediaPioneering Métis human rights advocate Muriel Stanley Venne dies at 87

If you are into horror games and still haven't played Silent Hill 2, now is a great chance to start as the PS5 version of Silent Hill 2 is more than half off at Walmart for Black Friday . As one of several Black Friday video game deals going on right now, the Silent Hill 2 remake was one highly requested by fans, and it did not disappoint. The game makes you uncomfortable but in an effective and thrilling way. In true horror fashion, there's blackout darkness, suffocating fog, unknown noises, grotesque enemies, and isolation. From our review, Matt Purslow states "The remake is a modern reminder not just of an era where Konami was a master of survival horror, but also the significant power of Silent Hill 2’s unrelenting misery." So, are you ready to play one of the best horror games of all time? Get Silent Hill 2 for $30 ( $69 ) More PlayStation Black Friday Deals We've Found On the video game front, we found Final Fantasy VII Rebirth (which is fantastic) is at its lowest price ever. Alternatively, if you prefer FromSoftware, Elden Ring is also on sale which gives you an easy way to enjoy this year’s Game of the Year-nominated Shadow Of the Erdtree DLC (which is also discounted right now . If you want to convince a friend to grab a PlayStation 5 to play with you, or you're the greatest gift-giver of all time, you can spread the word or grab this deal on a PS5 now . If you’ve been looking to try out VR, the PSVR2 Horizon: Call of the Mountain bundle is $250 off . For more PlayStation deals, check out our hub for the best PlayStation Black Friday deals . Top 10 Walmart Black Friday Deals When Is Black Friday 2024? We’re in the home stretch: Black Friday falls on November 29 this year. All month long, retailers have been rolling out sales, ramping up to massive discounts on Black Friday and through the weekend into Cyber Monday. As mentioned above, there are already fantastic deals on PS5 consoles (including PSVR2 ), PS5 controllers , and tons more. Brian Barnett writes reviews, guides, features, & more for IGN, GameSpot, & Kotaku. You can get more than your fair share of him on Bluesky & Backloggd , & enjoy his absurd video game talk show, The Platformers, on Spotify & Apple Podcasts .

LAS VEGAS, Dec. 23, 2024 (GLOBE NEWSWIRE) -- Hyperscale Data, Inc. (NYSE American: GPUS), a diversified holding company (“ Hyperscale Data ” or the “ Company ”), announced that it was notified today by the NYSE American that due to the Company’s disclosure in its Form 10-Q filed for the fiscal period ended September 30, 2024, which reported stockholders’ equity of approximately $2.2 million, it no longer meets the requirement that it must have no less than $6 million or more in stockholders’ equity pursuant to the listing standard set forth under Section 1003(a)(ii) and (iii) of the NYSE American Company Guide (the “ Listing Standards ”) because the Company has reported losses from continuing operations and/or net losses in five of its most recent fiscal years ended December 31, 2023. Under the applicable NYSE American listing rules, the Company must by January 17, 2025 submit a compliance plan that demonstrates how it intends to regain compliance with the Listing Standards within 18 months of the receipt of the notice, or June 18, 2026. The Company intends to develop and submit to the NYSE American such a plan. If the NYSE American does not accept the plan, or if the Company does not make progress consistent with the plan during the plan period, the NYSE American will initiate delisting procedures. If the NYSE American accepts the plan the Company will be subject to periodic reviews including quarterly monitoring for compliance with the plan. During this period, the Company's common stock will continue to be listed on the NYSE American and trade as usual subject to compliance with other NYSE American listing requirements. The Company is confident that it will be able to submit a plan acceptable to the NYSE American within the requisite period and further that it will promptly be able to demonstrate that it has regained compliance with the Listing Standards. For more information on Hyperscale Data and its subsidiaries, Hyperscale Data recommends that stockholders, investors and any other interested parties read Hyperscale Data’s public filings and press releases available under the Investor Relations section at hyperscaledata.com or available at www.sec.gov. About Hyperscale Data, Inc. Hyperscale Data is transitioning from a diversified holding company pursuing growth by acquiring undervalued businesses and disruptive technologies with a global impact to becoming solely an owner and operator of data centers to support high performance computing services. Through its wholly and majority-owned subsidiaries and strategic investments, Hyperscale Data owns and operates a data center at which it mines digital assets and offers colocation and hosting services for the emerging artificial intelligence ecosystems and other industries. It also provides, through its wholly owned subsidiary, Ault Capital Group, Inc., mission-critical products that support a diverse range of industries, including an artificial intelligence software platform, social gaming platform, equipment rental services, defense/aerospace, industrial, automotive, medical/biopharma and hotel operations. In addition, Hyperscale Data is actively engaged in private credit and structured finance through a licensed lending subsidiary. Hyperscale Data’s headquarters are located at 11411 Southern Highlands Parkway, Suite 240, Las Vegas, NV 89141. Forward-Looking Statements This press release contains “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. These forward-looking statements generally include statements that are predictive in nature and depend upon or refer to future events or conditions, and include words such as “believes,” “plans,” “anticipates,” “projects,” “estimates,” “expects,” “intends,” “strategy,” “future,” “opportunity,” “may,” “will,” “should,” “could,” “potential,” or similar expressions. Statements that are not historical facts are forward-looking statements. Forward-looking statements are based on current beliefs and assumptions that are subject to risks and uncertainties. Forward-looking statements speak only as of the date they are made, and the Company undertakes no obligation to update any of them publicly in light of new information or future events. Actual results could differ materially from those contained in any forward-looking statement as a result of various factors. More information, including potential risk factors, that could affect the Company’s business and financial results are included in the Company’s filings with the U.S. Securities and Exchange Commission, including, but not limited to, the Company’s Forms 10-K, 10-Q and 8-K. All filings are available at www.sec.gov and on the Company’s website at www.hyperscaledata.com . Hyperscale Data Investor Contact: IR@hyperscaledata.com or 1-888-753-2235

The Philadelphia Eagles (8-2) are set to play the Los Angeles Rams (5-5) on Sunday night. The Week 12 matchup will feature an Eagles team inching closer to securing the NFC East title. The Rams are in a three-way tie with the San Francisco 49ers and Seattle Seahawks for second place in the NFC West. The Eagles had several key players battling injury this week. Bryce Huff has been dealing with a wrist injury since Philadelphia’s 28-23 win over the Jacksonville Jaguars on Nov. 3. The Philadelphia Eagles lose Bryce Huff for four games Per the Eagles website, Huff was placed on injured reserve Friday “Huff was scheduled to undergo a wrist procedure on Thursday that will hopefully allow him to return before the end of the season. He will miss at least the next four games, starting with Sunday night’s prime-time showdown in Los Angeles.” Sirianni praised Huff for battling through the injury. “He’s really done a good job of batting through, but this will hopefully help him get some more function in that hand,” Sirianni said. Huff has recorded 2.5 sacks and a forced fumble in 2024. He’s made five starts and appeared in 10 games. DeVonta Smith will not play Sunday night The Eagles had more awful news before Sunday’s contest. Per the Week 12 injury report released on Friday, the Eagles have ruled out wide receiver DeVonta Smith due to a hamstring issue. The star receiver has battled the injury for a few weeks, but will not make it Sunday night. Friday's Injury Report #PHIvsLAR pic.twitter.com/hEyV5JAj0Q — Philadelphia Eagles (@Eagles) November 22, 2024 Smith is the Eagles second-leading receiver with 41 receptions for 516 yards and four touchdowns in 2024. This article first appeared on Gridiron Heroics and was syndicated with permission.he traditional games on Thursday will open with , followed by and in the evening the day will close with , to start week 13 of the 2024 season. Quarterback will be looking to continue his streak of icy victories when he and the visit the at . Tagovailoa has thrown seven combined touchdown passes without interceptions in his last two games, home wins over the Raiders and Patriots, but against the Packers he could struggle to keep up that pace. One of the matchups to watch will be of the against the run defense: rushed for three touchdowns on Sunday and has seven total touchdowns (six rushing, one receiving) in his last five games, while the allow 106.9 rushing yards per game. In the background, the lead the series, but the Packers have won the last three meetings and six of the last eight. What day is the Miami Dolphins vs Green Bay Packers Thanksgiving Day game? The match will take place on Thursday, November 28, 2024. Where is the Miami Dolphins vs Green Bay Packers Thanksgiving Day game? The duel will take place at in What time is the Miami Dolphins vs Green Bay Packers Thanksgiving Day game? Kickoff is scheduled for 20:20 ET/17:20 PT Where to watch Miami Dolphins vs Green Bay Packers on Thanksgiving Day? Via streaming you can follow the game through and . Where to watch Miami Dolphins vs Green Bay Packers on Thanksgiving Day in the USA? The match will be broadcast on the channel.

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