Jimmy Carter, the 39th US president, has died at 100Reports: Abe Shinzo's Widow Akie to Dine with Trump at Mar-a-Lago
Japanese researchers test pioneering drug to regrow teeth‘They’re not stupid’: Her mission is to give a voice to people with aphasia who have lost the ability to speak
US wholesale inflation accelerated in November in sign that some price pressures remain elevated WASHINGTON (AP) — Wholesale costs in the United States picked up sharply last month, signaling that price pressures are still evident in the economy even though inflation has tumbled from the peak levels it hit more than two years ago. The producer price index — which tracks inflation before it reaches consumers — rose 0.4% last month from October, up from 0.3% the month before. Measured from 12 months earlier, wholesale prices climbed 3% in November, the sharpest year-over-year rise since February 2023. Higher food prices helped fuel the November wholesale inflation reading, which was higher than economists had expected. Senate begins final push to expand Social Security benefits for millions of people WASHINGTON (AP) — The Senate is pushing toward a vote on legislation that would provide full Social Security benefits to millions of people. Senate Majority Leader Chuck Schumer began the process on Thursday for a final vote on the bill, known as the Social Security Fairness Act. It would eliminate policies that currently limit Social Security payouts for roughly 2.8 million people. The legislation has passed the House. The bill would add more strain on the Social Security Trust funds, which are already estimated to be unable to pay out full benefits beginning in 2035. The measure would add an estimated $195 billion to federal deficits over 10 years, according to the Congressional Budget Office. IRS recovers $4.7 billion in back taxes and braces for cuts with Trump and GOP in power WASHINGTON (AP) — IRS leadership on Thursday announced that the agency has recovered $4.7 billion in back taxes and proceeds from a variety of crimes. The announcement comes under the backdrop of a promised reckoning from Republicans who will hold a majority over both chambers of the next Congress and have long called for rescinding the tens of billions of dollars in funding provided to the agency by Democrats. IRS Commissioner Danny Werfel said improvements made to the agency will help the incoming administration and new Republican majority congress achieve its goals of administering an extension of the 2017 Tax Cuts and Jobs Act. From a 10-year-old to a Muppet to a president-elect, NYSE bell-ringers range from famous to obscure The first guest invited to ring the bell at the New York Stock Exchange in 1956 wasn’t a company executive, a politician or a well-known celebrity. It was a 10-year-old boy, Leonard Ross, who received the honor by winning a television quiz show.Since then, business titans, political giants and global film stars have all been among those ringing the opening bell at the NYSE. Ronald Reagan rang the bell as president in 1985. Billionaire businessman and former New York City Mayor Michael Bloomberg and Hollywood star Robert Downey Jr. - have also rung the bell. The list includes famous Muppets: Miss Piggy was once a bell ringer. Trump is named Time's Person of the Year and rings the New York Stock Exchange's opening bell NEW YORK (AP) — President-elect Donald Trump rang the opening bell at the New York Stock Exchange after being recognized by Time magazine as its person of the year. The honors Thursday for the businessman-turned-politician are a measure of Trump’s remarkable comeback from an ostracized former president who refused to accept his election loss four years ago to a president-elect who won the White House decisively in November. At the stock exchange, Trump was accompanied by his wife, Melania Trump, daughters Ivanka and Tiffany and Vice President-elect JD Vance. Trump grinned as people chanted “USA” before he opened the trading day and raised his fist. Ontario to restrict electricity exports to US and bar American-made alcohol if Trump tariffs applied TORONTO (AP) — A senior official in Canada’s most populous province says that Ontario could bar American-made alcohol and restrict electricity to three U.S. states if President-elect Donald Trump imposes sweeping tariffs on all Canadian products. The states are Michigan, New York and Minnesota. An official in Ontario Premier Doug Ford’s government said Thursday that it's contemplating restricting Ontario's liquor control board from buying American-made alcohol. Ontario is also considering restricting exports of Canadian critical minerals required for electric vehicle batteries. ECB cuts rates a quarter point amid concerns of tepid growth, impact of Trump trade policies FRANKFURT, Germany (AP) — The European Central Bank is cutting interest rates by a quarter percentage point amid signs of weakening growth and concern about the impact of political chaos in France and the possibility of new U.S. import tariffs. The bank’s rate-setting committee made the decision Thursday at its skyscraper headquarters in Frankfurt to lower the benchmark rate from 3.25% to 3%. Lower rates should support growth amid signs that the post-pandemic recovery is slowing in the 20 countries that use the euro currency and concerns that U.S. President-Elect Donald Trump might impose new tariffs, or import taxes, on goods imported to the US after he is inaugurated Jan. 20. YouTube TV is hiking its monthly price, again. Here's what to know NEW YORK (AP) — Are you a YouTube TV subscriber? Your monthly bills are about to get more expensive again. YouTube has announced that it’s upping the price of its streaming service’s base plan by $10 — citing rising content costs and other investments. The new $82.99 per month price tag will go into effect starting Jan. 13 for existing subscribers, and immediately for new customers who sign up going forward. YouTube TV has rolled out a series of price hikes over the years. When launched back in 2017, the going price of its streaming package was $35 a month. By 2019, that fee rose to $50 — and has climbed higher and higher since. Head of the Federal Aviation Administration to resign, allowing Trump to pick his successor The head of the Federal Aviation Administration says he will step down next month to let President-elect Donald Trump name his choice to lead the agency. Mike Whitaker announced his pending resignation in a message to FAA employees on Thursday. Since taking the helm at the FAA in October 2023, Whitaker has dealt with challenges that include a surge in close calls between planes, a shortage of air traffic controllers and antiquated equipment. He has led a tougher enforcement policy against Boeing since a panel blew off a jetliner in January. The White House is cracking down on overdraft fees NEW YORK (AP) — The Consumer Financial Protection Bureau said Thursday it's capping overdraft fees at $5 with a rule set to take effect in October 2025, if it isn't overturned by Congress or altered under a Trump administration. President Joe Biden had called the fees, which can be as high as $35, “exploitative,” while the banking industry has lobbied extensively to keep the existing fee structures in place.SAN DIEGO , Dec. 13, 2024 /PRNewswire/ -- Neurocrine Biosciences, Inc. (Nasdaq: NBIX) today announced the U.S. Food and Drug Administration has approved CRENESSITYTM (crinecerfont) capsules and oral solution as an adjunctive treatment to glucocorticoid replacement to control androgens in adult and pediatric patients four years of age and older with classic congenital adrenal hyperplasia (CAH), a rare, serious and lifelong genetic condition involving the adrenal glands. CRENESSITY, a potent and selective oral corticotropin-releasing factor type 1 receptor (CRF 1 ) antagonist, is the first and only classic CAH treatment that directly reduces excess adrenocorticotropic hormone (ACTH) and downstream adrenal androgen production, allowing for glucocorticoid dose reduction. It is a breakthrough in the treatment landscape for classic CAH. "For the last three decades, Neurocrine Biosciences, together with our late founder, Wylie W. Vale , has conducted groundbreaking research uncovering the critical role of corticotropin-releasing factor and its receptor, CRF 1 , in the pathophysiology of congenital adrenal hyperplasia," said Kyle W. Gano , Ph.D., Chief Executive Officer, Neurocrine Biosciences. "The approval of CRENESSITY is a significant milestone for the CAH community, and we are grateful to the individuals who participated in our clinical trials, including their families and caregivers, and to the clinical investigators who helped advance a new therapy and class of medicines." "Patients and families struggle to achieve balance between managing the symptoms of CAH and the side effects or complications of treatment with high-dose steroids, which may impact quality of life," said Dina Matos , Executive Director, CARES Foundation. "We are grateful to Neurocrine Biosciences for engaging with our community throughout the drug development process to understand our needs and ultimately providing this new medication that can help reduce excess adrenal androgens and the need for high-dose steroid treatment for individuals living with CAH." CRENESSITY is expected to be commercially available in approximately one week. The medication will be provided through PANTHERx Rare, a specialty pharmacy, to centralize and simplify CRENESSITY prescription fulfillment. Neurocrine Biosciences is committed to supporting patients in obtaining treatment with CRENESSITY by offering Neurocrine Access Support, a free, comprehensive assistance program created for patients, caregivers and healthcare providers. It offers a range of options to make sure patients have everything they need to begin and continue taking CRENESSITY. A dedicated Care Coordinator, backed by a team, is available to help patients and caregivers navigate the insurance process and identify appropriate financial assistance options. Most patients will pay $10 or less per month for CRENESSITY*. For more information, visit www.NBIaccess.com/crenessity or call 1-855-CRNSITY (276-7489) Monday-Friday 8 am-8 pm ET . *Additional terms and conditions apply. CAHtalyst TM Clinical Program Overview: The FDA approval is supported by the largest-ever clinical trial program of classic CAH, the CAHtalyst Pediatric and Adult Phase 3 global registrational studies. CAHtalyst Phase 3 data results in pediatric and adult patients with classic CAH were published in The New England Journal of Medicine . "The clinical results across both CAHtalyst studies support the efficacy and safety profile of CRENESSITY and its ability to reduce the overproduction of adrenal androgens, allowing for a meaningful reduction in glucocorticoid dosage, while maintaining or enhancing control of these androgens," said Richard Auchus , M.D., Ph.D., Professor, University of Michigan Health, Principal Investigator. "Chronic treatment with supraphysiologic glucocorticoids can cause a number of short- and long-term health consequences, such as obesity, hypertension and osteoporosis, so the ability for patients with CAH to lower their glucocorticoid dose to a more physiologic level can have profound benefits." In both CAHtalyst studies, CRENESSITY enabled lower steroid doses and decreased androgen levels. Phase 3 CAHtalyst Pediatric Study: Phase 3 CAHtalyst Adult Study: CRENESSITY was well tolerated with few treatment-related adverse events in both CAHtalyst studies. Pediatric and adult patients taking CRENESSITY had no treatment-related serious adverse events. Adrenal insufficiency and crisis are risks of living with CAH that CRENESSITY does not address and can occur when a patient's GC dose is too low. In the CAHtalyst Pediatric study, there were no cases of adrenal crisis among patients taking CRENESSITY or placebo. In the CAHtalyst Adult study, two patients (1.6%) taking CRENESSITY experienced adrenal crisis. No patients on placebo experienced adrenal crisis. However, one patient (1.7%) on placebo experienced adrenal insufficiency. Patients should work with their healthcare provider to manage GC dosing while taking CRENESSITY. For more information about CRENESSITY, visit Crenessity.com . About Congenital Adrenal Hyperplasia Congenital adrenal hyperplasia (CAH) is a rare genetic condition that results in an enzyme deficiency that alters the production of adrenal steroid hormones, such as cortisol, aldosterone and adrenal androgens, which are essential for life. Approximately 95% of CAH cases are caused by variants of the CYP21A2 gene that leads to deficiency of the enzyme 21-hydroxylase (21-OH). Severe deficiency of this enzyme leads to an inability of the adrenal glands to produce enough cortisol and, in approximately 75% of cases, aldosterone. Because individuals with CAH are still able to produce androgens, the unused precursors that would normally be used to make cortisol instead result in the production of excess amounts of androgens. If left untreated, CAH can result in salt wasting, dehydration and even death. Historically, exogenous glucocorticoids (GCs) have been used not only to correct the endogenous cortisol deficiency, but doses used are higher than cortisol replacement needed (supraphysiologic) to lower the levels of adrenocorticotropic hormone (ACTH) and adrenal androgens. However, GC treatment at high doses has been associated with serious and significant complications of steroid excess, including metabolic issues such as weight gain and diabetes, cardiovascular disease and osteoporosis. Additionally, long-term treatment with high-dose GCs may have psychological and cognitive impact, such as changes in mood and memory. Adrenal androgen excess has been associated with abnormal bone growth and development in pediatric patients, female health problems such as excess facial hair growth and menstrual irregularities, testicular rest tumors in males and fertility issues in both sexes. About The CAHtalystTM Studies The Phase 3 CAHtalystTM global registrational studies were designed to evaluate the safety, efficacy and tolerability of CRENESSITY in children and adults with classic congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency. The CAHtalyst studies were the largest-ever clinical trial program in classic CAH, including 285 pediatric and adult patients. The CAHtalyst Pediatric study included 103 pediatric patients aged four to 17 years. The study tested two questions. The first question evaluated whether four weeks of CRENESSITY treatment could improve androgen control. The second question evaluated whether an additional 24 weeks of CRENESSITY treatment enabled customized glucocorticoid (GC) down-titration while androstenedione levels were maintained or improved. The CAHtalyst Adult study included 182 adult patients aged 18 to 58 years. Similarly, the first question of the study evaluated whether four weeks of CRENESSITY treatment could improve androgen control, and the second question evaluated whether an additional 20 weeks of CRENESSITY treatment enabled GC reduction to physiologic range while androstenedione levels were maintained or improved. Data from the CAHtalyst Phase 3 studies supported approval of CRENESSITY by the U.S. Food and Drug Administration in December 2024. The open-label extension treatment portions of both studies are ongoing. About CRENESSITYTM (crinecerfont) CRENESSITYTM is a potent and selective, oral corticotropin-releasing factor type 1 receptor (CRF 1 ) antagonist developed to reduce and control excess adrenocorticotropic hormone (ACTH) and adrenal androgens through a non-glucocorticoid (GC) mechanism for the treatment of classic congenital adrenal hyperplasia (CAH). Antagonism of CRF 1 receptors in the pituitary has been shown to decrease ACTH levels, which in turn decreases the production of adrenal androgens and potentially the symptoms associated with CAH. The robust clinical study data demonstrate that lowering adrenal androgen levels with CRENESSITY enables lower, more physiologic dosing of GCs to replace missing cortisol. CRENESSITY comes in capsules and an oral solution. The capsule formulation is available in 50 mg and 100 mg doses. The oral solution is available as a 50 mg/mL strength formulation. For adults 18 years and older, the recommended dosage is 100 mg twice daily taken orally with a meal. For pediatric patients four to 17 years of age weighing less than 55 kg (121 lbs), the recommended dosage is based on body weight and is administered twice daily, taken orally with a meal. For pediatric patients weighing more than 55 kg (121 lbs), the recommended dosage is 100 mg twice daily taken orally with a meal. Healthcare providers can work with patients to determine the appropriate formulation for use depending on patient needs. Patients receiving CRENESSITY should continue GC therapy for cortisol replacement. Important Information Approved Uses CRENESSITY (crinecerfont) is a prescription medicine used together with glucocorticoids (steroids) to control androgen (testosterone-like hormone) levels in adults and children 4 years of age and older with classic congenital adrenal hyperplasia (CAH). IMPORTANT SAFETY INFORMATION Do not take CRENESSITY if you: Are allergic to crinecerfont, or any of the ingredients in CRENESSITY. CRENESSITY may cause serious side effects, including : Allergic Reactions. Symptoms of an allergic reaction include tightness of the throat, trouble breathing or swallowing, swelling of the lips, tongue, or face, and rash. If you have an allergic reaction to CRENESSITY, get emergency medical help right away and stop taking CRENESSITY. Risk of Sudden Adrenal Insufficiency or Adrenal Crisis With Too Little Glucocorticoid (Steroid) Medicine. Sudden adrenal insufficiency or adrenal crisis can happen in people with congenital adrenal hyperplasia who are not taking enough glucocorticoid (steroid) medicine. You should continue taking your glucocorticoid (steroid) medicine during treatment with CRENESSITY. Certain conditions such as infection, severe injury, or shock may increase your risk for sudden adrenal insufficiency or adrenal crisis. Tell your healthcare provider if you get a severe injury, infection, illness, or have planned surgery during treatment. Your healthcare provider may need to change your dose of glucocorticoid (steroid) medicine. Before taking CRENESSITY, tell your healthcare provider about all of your medical conditions, including if you are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed. Tell your healthcare provider about all the medicines you take , including prescription and over-the counter medicines, vitamins, and herbal supplements. The most common side effects of CRENESSITY in adults include tiredness, headache, dizziness, joint pain, back pain, decreased appetite, and muscle pain. The most common side effects of CRENESSITY in children include headache, stomach pain, tiredness, nasal congestion, and nose bleeds. These are not all the possible side effects of CRENESSITY. Call your healthcare provider for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit MedWatch at www.fda.gov/medwatch or call 1-800-FDA-1088. Dosage Forms and Strengths: CRENESSITY is available in 50 mg and 100 mg capsules and as an oral solution of 50 mg/mL. Please see full Prescribing Information About Neurocrine Biosciences, Inc. Neurocrine Biosciences is a leading neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs, but few options. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, neuroendocrine and neuropsychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, endometriosis* and uterine fibroids,* as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. For more information, visit neurocrine.com , and follow the company on LinkedIn , X (formerly Twitter) and Facebook . (*in collaboration with AbbVie) The NEUROCRINE BIOSCIENCES Logo Lockup and YOU DESERVE BRAVE SCIENCE are registered trademarks of Neurocrine Biosciences, Inc. CRENESSITY and CAHtalyst are trademarks of Neurocrine Biosciences, Inc. Forward-Looking Statements In addition to historical facts, this press release contains forward-looking statements that involve a number of risks and uncertainties. These statements include, but are not limited to, statements regarding the potential benefits to be derived from CRENESSITY for the treatment of classic congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency; the value and benefits CRENESSITY brings to patients with CAH; the ability of Neurocrine Biosciences to ensure patients have access to CRENESSITY; and whether the results from our clinical trials of CRENESSITY are indicative of real-world results. Factors that could cause actual results to differ materially from those stated or implied in the forward-looking statements include, but are not limited to, the following: risks and uncertainties associated with Neurocrine Biosciences' business and finances in general, as well as risks and uncertainties associated with the commercialization of CRENESSITY; whether CRENESSITY receives adequate reimbursement from third-party payors; the degree and pace of market uptake of CRENESSITY; risks and uncertainties relating to competitive products and technological changes that may limit demand for CRENESSITY; risks associated with the Company's dependence on third parties for development and manufacturing activities related to CRENESSITY, and the ability of the Company to manage these third parties; risks that additional regulatory submissions for CRENESSITY or other product candidates may not occur or be submitted in a timely manner; risks that the FDA or other regulatory authorities may make adverse decisions regarding CRENESSITY; risks that post-approval CRENESSITY commitments or requirements may be delayed; risks that CRENESSITY may be precluded from commercialization by the proprietary or regulatory rights of third parties, or have unintended side effects, adverse reactions or incidents of misuse; risks and uncertainties relating to competitive products and technological changes that may limit demand for CRENESSITY; and other risks described in the Company's periodic reports filed with the Securities and Exchange Commission, including without limitation the Company's quarterly report on Form 10-Q for the quarter ended September 30, 2024 . Neurocrine Biosciences disclaims any obligation to update the statements contained in this press release after the date hereof other than required by law. © 2024 Neurocrine Biosciences, Inc. All Rights Reserved. CP-CFT-US-0070 12/2024 View original content to download multimedia: https://www.prnewswire.com/news-releases/neurocrine-biosciences-announces-fda-approval-of-crenessity-crinecerfont-a-first-in-class-treatment-for-children-and-adults-with-classic-congenital-adrenal-hyperplasia-302331772.html SOURCE Neurocrine Biosciences, Inc.
These companies innovate and collaborate without office mandatesShares of Costco Wholesale Co. ( NASDAQ:COST – Get Free Report ) fell 1.8% during mid-day trading on Friday . The stock traded as low as $937.43 and last traded at $939.38. 402,343 shares were traded during trading, a decline of 79% from the average session volume of 1,937,516 shares. The stock had previously closed at $956.14. Analysts Set New Price Targets COST has been the topic of several research analyst reports. The Goldman Sachs Group upped their price objective on shares of Costco Wholesale from $876.00 to $995.00 and gave the stock a “buy” rating in a research note on Friday, September 27th. Telsey Advisory Group reiterated an “outperform” rating and issued a $1,050.00 price objective on shares of Costco Wholesale in a research report on Friday, December 13th. Melius Research assumed coverage on Costco Wholesale in a report on Monday, September 23rd. They set a “hold” rating and a $950.00 target price on the stock. Raymond James lifted their price target on Costco Wholesale from $990.00 to $1,030.00 and gave the company an “overweight” rating in a report on Thursday, December 12th. Finally, Redburn Atlantic lowered shares of Costco Wholesale from a “buy” rating to a “neutral” rating and increased their price objective for the stock from $860.00 to $890.00 in a report on Tuesday, September 10th. Nine research analysts have rated the stock with a hold rating and nineteen have assigned a buy rating to the company. According to data from MarketBeat.com, the company has a consensus rating of “Moderate Buy” and a consensus price target of $1,011.74. Get Our Latest Stock Report on COST Costco Wholesale Price Performance Costco Wholesale ( NASDAQ:COST – Get Free Report ) last issued its quarterly earnings data on Thursday, September 26th. The retailer reported $5.15 earnings per share for the quarter, beating the consensus estimate of $5.05 by $0.10. Costco Wholesale had a net margin of 2.93% and a return on equity of 33.19%. The company had revenue of $79.70 billion for the quarter, compared to analyst estimates of $79.91 billion. During the same period in the prior year, the firm earned $4.86 earnings per share. The company’s revenue was up 1.0% on a year-over-year basis. As a group, research analysts predict that Costco Wholesale Co. will post 17.83 EPS for the current fiscal year. Costco Wholesale Announces Dividend The company also recently disclosed a quarterly dividend, which was paid on Friday, November 15th. Stockholders of record on Friday, November 1st were issued a dividend of $1.16 per share. This represents a $4.64 dividend on an annualized basis and a dividend yield of 0.49%. The ex-dividend date was Friday, November 1st. Costco Wholesale’s dividend payout ratio is presently 27.25%. Insider Transactions at Costco Wholesale In other Costco Wholesale news, EVP Russell D. Miller sold 4,400 shares of the stock in a transaction that occurred on Friday, October 11th. The shares were sold at an average price of $891.15, for a total transaction of $3,921,060.00. Following the transaction, the executive vice president now owns 10,202 shares in the company, valued at $9,091,512.30. This represents a 30.13 % decrease in their position. The sale was disclosed in a document filed with the SEC, which is available at this hyperlink . Also, EVP Claudine Adamo sold 3,200 shares of Costco Wholesale stock in a transaction that occurred on Monday, September 30th. The shares were sold at an average price of $888.99, for a total transaction of $2,844,768.00. Following the completion of the sale, the executive vice president now owns 8,630 shares of the company’s stock, valued at approximately $7,671,983.70. The trade was a 27.05 % decrease in their ownership of the stock. The disclosure for this sale can be found here . Over the last quarter, insiders have sold 11,016 shares of company stock worth $9,826,115. Company insiders own 0.18% of the company’s stock. Hedge Funds Weigh In On Costco Wholesale Several hedge funds and other institutional investors have recently added to or reduced their stakes in the stock. RPg Family Wealth Advisory LLC bought a new stake in Costco Wholesale during the third quarter worth about $29,000. Fairway Wealth LLC lifted its holdings in shares of Costco Wholesale by 230.0% during the 2nd quarter. Fairway Wealth LLC now owns 66 shares of the retailer’s stock worth $56,000 after acquiring an additional 46 shares during the period. Mowery & Schoenfeld Wealth Management LLC acquired a new stake in shares of Costco Wholesale during the 3rd quarter worth approximately $58,000. Christopher J. Hasenberg Inc raised its position in Costco Wholesale by 329.4% during the third quarter. Christopher J. Hasenberg Inc now owns 73 shares of the retailer’s stock valued at $65,000 after purchasing an additional 56 shares in the last quarter. Finally, VitalStone Financial LLC bought a new stake in Costco Wholesale during the third quarter worth $71,000. 68.48% of the stock is owned by institutional investors and hedge funds. About Costco Wholesale ( Get Free Report ) Costco Wholesale Corporation, together with its subsidiaries, engages in the operation of membership warehouses in the United States, Puerto Rico, Canada, Mexico, Japan, the United Kingdom, Korea, Australia, Taiwan, China, Spain, France, Iceland, New Zealand, and Sweden. The company offers branded and private-label products in a range of merchandise categories. Featured Stories Receive News & Ratings for Costco Wholesale Daily - Enter your email address below to receive a concise daily summary of the latest news and analysts' ratings for Costco Wholesale and related companies with MarketBeat.com's FREE daily email newsletter .
Wayne Rooney has encouraged I’m A Celebrity... Get Me Out Of Here! viewers to vote for his wife to do a Bushtucker Trial as he feels she would want to “put herself to the test”. The former England footballer, 39, said he was “proud” of how Coleen was doing in the Australian jungle in a post on social media on Saturday. The couple, who first met at school and began dating aged 16, share four sons – Kai Wayne, Klay Anthony, Kit Joseph and Cass Mac. “Proud of @ColeenRoo on @imacelebrity she’s doing great”, he wrote on X, formerly Twitter, alongside a collage of photos of her on the show. “Me and the boys would love to see her doing a trial and we know she’d want to put herself to the test. “If you can download the #ImACeleb and let’s get voting!” During the first task of the series, BBC Radio 1 presenter Dean McCullough chose to partner up with TV personality Coleen as he hailed her as “Wagatha Christie”. Rooney, 38, was given the nickname when she accused Rebekah Vardy , who is married to Leicester City striker Jamie Vardy , of leaking her private information to The Sun in a viral post on social media. In July 2022, a judge at the High Court found the post was “substantially true”. During Vardy’s stint on I’m A Celebrity, she became the third celebrity to leave, saying the series helped her become more tolerant. Earlier this week, Liverpool-born Coleen told her fellow campmate that going to court over her feud with Vardy was her “worst nightmare” as she felt she was “putting on a show for the whole world”. However, she said she was not scared about making the viral post which kicked off the dispute, saying: “I just didn’t think it would have the impact it did, because I was just that sick and tired of it, it was draining.” Later in the episode, Rooney became emotional over the loss of her sister Rosie, after boxing star Barry McGuigan spoke about the death of his daughter. I’m A Celebrity... Get Me Out Of Here! continues on ITV1 and ITVX.When dockworkers walked the picket line in October, the strike lasted for 3 days. And if a new contract between their 45,000 member union and the U.S. Maritime Alliance isn't signed by mid-January — a longer strike could send inflation going in the wrong direction. Just months after a strike at Gulf and East Coast ports ended, operators and union members are now at an impasse — once again — over automation. Port operators say they need more technology to increase port efficiency, improve safety and to control costs. But union members say no, because some workers will lose their jobs. A new strike could come if an agreement isn't reached by January 15. And if that happens inflation could increase, when goods aren't flowing in an out of ports as quickly. Thursday union leaders met with President-elect Donald trump at Mar-a-Lago and walked away with his support. Writing about automation on Truth social, Trump said "the amount of money saved is nowhere near the distress, hurt, and harm it causes for American workers," and that foreign countries "...shouldn't be looking for every last penny knowing how many families are hurt." RELATED STORY | Billions of dollars of U.S. economic activity halted as port workers enter day two of their strike Professor Todd Belt of George Washington University called it Trump striking a different path than he did during his first term. "During the first Trump term you had Donald Trump, surrounded by a lot of people who were suggested to him by incumbent Republicans who had really a Republican orthodoxy on free trade. Donald trump now is going to be surrounded by a lot of people who support his ideas of interventionism and tariffs, as well as other trade policies that will protect working people at the expense of, of course, inflation," Belt said. The International Longshoremen's Association has until Jan. 15 to negotiate a new contract with the U.S. Maritime Alliance, which represents ports and shipping companies. At the heart of the dispute is whether ports can install automated gates, cranes and container-moving trucks that could make it faster to unload and load ships. The union argues that automation would lead to fewer jobs, even though higher levels of productivity could do more to boost the salaries of remaining workers. The Maritime Alliance said in a statement that the contract goes beyond ports to "supporting American consumers and giving American businesses access to the global marketplace — from farmers, to manufacturers, to small businesses, and innovative start-ups looking for new markets to sell their products." "To achieve this, we need modern technology that is proven to improve worker safety, boost port efficiency, increase port capacity, and strengthen our supply chains," said the alliance, adding that it looks forward to working with Trump. In October, the union representing 45,000 dockworkers went on strike for three days, raising the risk that a prolonged shutdown could push up inflation by making it difficult to unload container ships and export American products overseas. The issue pits an incoming president who won November's election on the promise of bringing down prices against commitments to support blue-collar workers along with the kinds of advanced technology that drew him support from Silicon Valley elite such as billionaire Elon Musk. Trump sought to portray the dispute as being between U.S. workers and foreign companies, but advanced ports are also key for staying globally competitive. China is opening a $1.3 billion port in Peru that could accommodate ships too large for the Panama Canal. There is a risk that shippers could move to other ports, which could also lead to job losses. Mexico is constructing a port that is highly automated, while Dubai, Singapore and Rotterdam already have more advanced ports. "For the great privilege of accessing our markets, these foreign companies should hire our incredible American Workers, instead of laying them off, and sending those profits back to foreign countries," Trump posted. "It is time to put AMERICA FIRST!" The Associated Press contributed to this report.
Chargers defensive coordinator Jesse Minter calls the Baltimore star 'the most electric quarterback' in the history of the NFL ahead of Monday night's game
Los Angeles Deputy Mayor of Public Safety Brian Williams was placed on administrative leave following an investigation into a bomb threat he allegedly made against City Hall earlier this year, Mayor Karen Bass’ office announced on Wednesday, Dec. 1. The Mayor’s Office was notified that the FBI searched Williams’ home Tuesday as part of their investigation, according to a statement from the office. “The mayor takes this matter very seriously,” Deputy Mayor of Communications Zach Seidl said in a statement. “When the threat was reported, LAPD investigated and determined there was no immediate danger. Following additional investigation, LAPD referred this matter to the FBI for further investigation.” According to a Los Angeles Police Department statement, the agency’s initial investigation determined Williams was likely the “source of the threat.” “Due to the department’s working relationship with Mr. Williams, the investigation was referred to the FBI,” LAPD said in a statement. “The FBI remains the investigating agency.” “No additional information is being released,” the LAPD added. A representative for the FBI did not immediately respond to a request for comment. Williams joined Bass’ office in March 2023. He was tasked with working closely with critical safety departments such as police, fire, Los Angeles World Airports police, and emergency. Prior to his appointment, Williams served seven years as the executive director of the Los Angeles County Sheriff Civilian Oversight Commission. Williams also previously served as deputy mayor under Mayor James Hahn, where he was responsible for the management and oversight of the Department of Transportation, Public Works and Information Technology Agency.Major change to Aussie passports coming within days
New e-tattoos developed by University of Texas researchers can track brainwavesGretchen McKay | (TNS) Pittsburgh Post-Gazette PITTSBURGH — Many Americans consider social media a scourge, but for a home cook, it can be a fun and informative place to get help deciding what to eat. Sure, some of the recipes would-be influencers recommend are in fact pretty abominable — check out @chefreactions on TikTok, Instagram or X for many, many examples — but I have stumbled across some pretty good recipes on many occasions, too. Related Articles Restaurants Food and Drink | In season: The universal joy of carrots Restaurants Food and Drink | Don’t shun pinot grigio! The good versions of wines you think are bad Restaurants Food and Drink | Quick Fix: Horseradish Crusted Snapper with Arugula Pasta Restaurants Food and Drink | 3 recipes to help you through the busy holiday season Restaurants Food and Drink | Roasted orange delivers big flavor in this smoky chicken traybake One that’s been going viral for a while and but only recently caught my eye shines a spotlight on the creamy, tomatoey dish known as Marry Me chicken. There are probably as many recipes for Marry Me chicken on social media as there are cooks. (Delish claims to have created the video recipe for the original dish, also known as Tuscan chicken, in 2016.) But in my opinion, the best variations hang their chef’s hat on a sauce made with sun-dried tomatoes, garlic and cream. Yum! This rich and luxurious entree is a definite step above the “engagement” chicken that caused a similar stir when it made its debut in Glamour magazine in 2004. That proposal-worthy recipe — saved for posterity in the 2011 cookbook “100 Recipes Every Woman Should Know: Engagement Chicken and 99 Other Fabulous Dishes to Get You Everything You Want in Life” — featured a whole chicken roasted with lemon and herbs. Awesome for sure, but not nearly as swoon worthy. I’ve been married for a very long time, so I’m not looking for a dish that will get me engaged. But who wouldn’t want applause when they put dinner on the table? That’s how Delish’s original recipe made it into the latest installment of “Dinner for Four for $25.” Usually when I’m building these economical meals, I do all my shopping in one store. This time, I shopped over the course of a weekend at some of my favorite haunts to see if that made a difference. (And no, I didn’t factor in the cost of gas, but maybe should have!) First stop after downing my Saturday morning latte and Nutella mele at a street-side table at Colangelo’s in the Strip District: Wholey’s Market, where I found boneless chicken breast at the bargain price of $3.89 per pound. I then crossed the street and headed down the block to Pennsylvania Macaroni Co., where I found several varieties of sun-dried tomatoes to chose from. I went with a jar of Ponti sun-dried cherry tomatoes for $5.09 — a definite splurge when your budget is only $25, but an ingredient I knew would deliver plenty of flavor. At Aldi, I found a bag of five huge lemons for $3.89, or 78 cents apiece, and a nice package of fresh broccoli for $2.28. A bargain, considering I would only use about two-thirds of it. The German supermarket chain known for its low prices and no-frills shopping experience (you have to deposit a quarter to get a shopping cart) also had butter — a main ingredient in my sandwich cookie dessert — on sale for $3.99 a pound. A bag of powdered sugar was pretty cheap, too, at just $2.09 for a two-pound bag. “Shopping” my pantry for ingredients I always have on hand, including garlic, olive oil, spices, rice, molasses and vanilla, once again helped keep costs down. Total bill: $24.38, or 62 cents under budget. Not bad when you consider the homemade dessert recipe makes more oatmeal sandwich cookies than a family can/should eat at one sitting. PG tested Sun-dried tomatoes could be considered a splurge item because even a tiny jar is expensive, but their concentrated, sweet and tangy tomato goodness add so much flavor to a dish! They are certainly the star of this chicken dish that has been making the rounds on social media platforms. Some say the entree is so good, you’ll get a marriage proposal out of it. At any rate, the Parmesan cream sauce that gets spooned on top of the chicken and rice will certainly make your diners swoon. This original recipe from Delish.com is a pretty easy dish to get on the table in quick fashion. Just remember to use a dry pot holder to take the pan out of the oven because it will be very hot; I very stupidly used a damp dish towel and now have another cooking scar. 4 (8-ounce) boneless, skinless chicken breasts Kosher salt Freshly ground black pepper 3 tablespoons extra virgin olive oil, divided 2 cloves garlic, finely chopped 1 tablespoons fresh thyme leaves 1 teaspoon crushed red pepper flakes 3/4 cup chicken broth 1/2 cup chopped sun-dried tomatoes packed in oil 1/2 cup heavy cream 1/4 cup finely grated Parmesan Fresh basil, torn, for serving, optional Cooked rice, for serving Preheat oven to 375 degrees. In a large ovenproof skillet over medium-high heat, heat 1 tablespoon oil. Generously season chicken with salt and black pepper and cook, turning halfway through, until golden brown, about 5 minutes per side. Transfer chicken to a plate. In same skillet over medium heat, heat remaining 2 tablespoons oil. Stir in garlic, thyme and red pepper flakes. Cook, stirring, until fragrant, about 1 minute. Stir in broth, tomatoes, cream, and Parmesan; season with salt. Bring to a simmer, then return chicken and any accumulated juices to skillet. Transfer skillet to oven. Bake chicken until cooked through and juices run clear when chicken is pierced with a knife, 10-12 minutes. Arrange chicken on a platter. Spoon sauce over. Top with basil, if using, and serve with cooked rice. Serves 4. — delish.com PG tested Broccoli is a reliable veggie when you need a little something extra to round out a meal and don’t want to spend a fortune. Here, it’s blanched until crisp-tender and then tossed with lemon juice and zest and a pinch of red pepper flakes. I used lemon olive oil (already on hand) for an extra burst of citrus flavor. 1 large bunch broccoli, separated into florets 2 tablespoons olive oil or butter 1 clove garlic, minced Juice and zest of 1/2 lemon 1 pinch (or two) red pepper flakes Flaky salt and freshly ground ground black pepper, to taste Place broccolini in a large skillet with about 2 inches of water; bring to a boil and cook until bright green, 1-2 minutes. Drain. Heat olive oil in the same skillet over medium heat. Stir in garlic and cook until golden and fragrant, 1-2 minutes. Add broccoli; cook and stir until heated through, 2-3 minutes. Squeeze lemon juice and zest over broccoli and season with red pepper flakes, salt, and pepper. Serves 4. — Gretchen McKay, Post-Gazette PG tested Remember how if you were lucky when you were a kid you got an individually wrapped Little Debbie Oatmeal Creme Pie in your lunchbox? These soft and chewy oatmeal cookies sandwiched with vanilla buttercream taste exactly the same. Actually, they’re better because they’re not made with corn syrup and artificial flavorings, but rather real butter and brown sugar. It’s important to let the cookies cool on the baking sheet for a few minutes before transferring them to a rack. Otherwise they will fall apart. The icing is very sweet, so you might want to reduce the amount of powdered sugar. For cookies 1/2 cup unsalted butter, at room temperature 1 cup packed light brown sugar 1 tablespoon molasses 1 large egg, room temperature 1 teaspoon vanilla 1 1/4 cups all-purpose flour 1/2 cup old-fashioned oats 3/4 teaspoon baking soda 1/2 teaspoon salt For filling 1/2 cup unsalted butter, at room temperature 3 cups powdered sugar 2 tablespoons heavy cream 2 teaspoons vanilla Pinch of salt Preheat oven to 325 degrees and line two sheet pans with parchment paper. In stand mixer outfitted with whisk attachment add butter, brown sugar and molasses and beat on low speed until combined. Gradually increase speed to medium-high and beat until smooth, about 2 minutes. Scrape down sides and bottom of bowl with spatula, then add egg and vanilla extract. Beat on medium-high speed until combined. Add flour, oats, baking soda and salt and beat on low speed until just combined and no streaks of flour remain. Use a 1/2 -ounce cookie scoop tor tablespoon measure to portion out equal amounts of dough. Roll the dough in your hands to smooth the edges, then place 2 inches apart on prepared pans. Bake until cookies have puffed up and are set and firm around the edges but still somewhat soft in the middle, 9-11 minutes. Remove sheet pans from oven and allow cookies to rest on the pans for 5 minutes, then use a metal spatula to transfer cookies to a cooling rack to cool completely. Once cookies have cooled, make filling. In stand mixer fitted with the paddle attachment, combine butter, confectioners’ sugar, cream, vanilla and salt. Beat on low speed, gradually increasing the speed to high, until creamy and fully incorporated, about 45 seconds. If filling is dry, add a small splash or two of cream. Assemble cookies. Using a small offset spatula or butter knife to spread about 2 tablespoons of filling onto the bottom side of one cookie, then place second cookie on top to sandwich. Repeat with remaining cookies and serve. Makes 16 sandwich cookies. —”Sweet Tooth” by Sarah Fennel (Clarkson Potter, $35) ©2024 PG Publishing Co. Visit at post-gazette.com. Distributed by Tribune Content Agency, LLC.
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Daily Post Nigeria CAF Awards 2024: Nnadozie battles Banda, Mssoudy for POTY Home News Politics Metro Entertainment Sport Sport CAF Awards 2024: Nnadozie battles Banda, Mssoudy for POTY Published on December 12, 2024 By Mike Oyebola Super Falcons goalkeeper Chiamaka Nnadozie has been named among the final nominees for the 2024 CAF Women’s Player of the Year. Zambia forward Barbara Banda and Morocco’s Sanna Mssoudy are the other players nominated for the prestigious award. Nnadozie is also in contention for the Goalkeeper of the Year. The 24-year-old will be looking to succeed her compatriot, Asisat Oshoala, who won the award last year. Oshoala has won the award for a record six times. Nnadozie impressed for Nigeria at the 2024 Olympic Games in Paris. Related Topics: Don't Miss UCL: Saka, Olise included as UEFA unveils Champions League team [Full list] You may like CAF Awards 2024: Okwuchukwu makes final shortlist for women’s young POTY CAF Awards 2024: Edo Queens battle TP Mazembe, AS FAR for Women’s Club of the Year Nnadozie targets WAFCON glory with Super Falcons CAF Awards 2024: Nnadozie makes women’s Player of the Year final shortlist CAF Awards 2024: Nnadozie, Okwuchukwu, Super Falcons in final shortlists France boss lauds Nnadozie despite victory over Super Falcons Advertise About Us Contact Us Privacy-Policy Terms Copyright © Daily Post Media LtdST. LOUIS (AP) — Fourteen North Korean nationals have been indicted in a scheme using information technology workers with false identities to contract with U.S. companies — workers who then funneled their wages to North Korea for development of ballistic missiles and other weapons, the head of the FBI office in St. Louis said Thursday. The scheme involving thousands of IT workers generated more than $88 million for the North Korean government, Ashley T. Johnson, special agent in charge of the St. Louis FBI office, said at a news conference. In addition to their wages, the workers stole sensitive information from companies or threatened to leak information in exchange for extortion payments, Johnson said. Victims included defrauded companies and people whose identities were stolen from across the U.S., including Missouri, Johnson said. The indictments were filed Wednesday in U.S. District Court in St. Louis. All 14 people face wire fraud, money laundering, identity theft and other charges. Most of those accused are believed to be in North Korea. Johnson acknowledged that bringing them to justice will be difficult. To help, the U.S. Department of State is offering a $5 million reward for information leading to any of the suspects. Federal authorities said the scheme worked like this: North Korea dispatched thousands of IT workers to get hired and work remotely or as freelancers for U.S. companies. The IT workers involved in the scheme sometimes used stolen identities. In other instances, they paid Americans to use their home Wi-Fi connections, or to pose in on-camera job interviews as the IT workers. Johnson said the FBI is going after those “domestic enablers,” too. “This is just the tip of the iceberg,” Johnson said. “If your company has hired fully remote IT workers, more likely than not, you have hired or at least interviewed a North Korean national working on behalf of the North Korean government,” Johnson said. The Justice Department in recent years has sought to expose and disrupt a broad variety of criminal schemes aimed at bolstering the North Korean regime, including its nuclear weapons program. In 2021, the Justice Department charged three North Korean computer programmers and members of the government’s military intelligence agency in a broad range of global hacks that officials say were carried out at the behest of the regime. Law enforcement officials said at the time that the prosecution highlighted the profit-driven motive behind North Korea’s criminal hacking, a contrast from other adversarial nations like Russia, China and Iran that are generally more interested in espionage, intellectual property theft or even disrupting democracy. In May 2022, the State Department, Department of the Treasury, and the FBI issued an advisory warning of attempts by North Koreans “to obtain employment while posing as non-North Korean nationals.” The advisory noted that in recent years, the regime of Kim Jong Un “has placed increased focus on education and training” in IT-related subjects. In October 2023 , the FBI in St. Louis announced the seizure of $1.5 million and 17 domain names as part of the investigation. The indictments announced Tuesday were the first stemming from the investigation. Johnson urged companies to thoroughly vet IT workers hired to work remotely. “One of the ways to help minimize your risk is to insist current and future IT workers appear on camera as often as possible if they are fully remote,” she said. Officials didn’t name the companies that unknowingly hired North Korean workers.
Time magazine gave Donald Trump something it has never done for a designee: a lengthy fact-check of claims he made in an accompanying interview. The accompanies a transcript of what the president-elect told the newsmagazine’s journalists. Described as a “12 minute read,” it calls into question 15 separate statements that Trump made. It was the second time Trump earned the Time accolade; he also won in 2016, the first year he was elected president. Time editors said it wasn’t a particularly hard choice over other finalists Kamala Harris, Elon Musk, Benjamin Netanyahu and Kate Middleton. Time said Friday that no other Person of the Year has been fact-checked in the near-century that the magazine has annually written about the figure that has had the greatest impact on the news. But it has done the same for past interviews with the likes of Joe Biden, Netanyahu and Trump. Such corrections have been a sticking point for Trump and his team in the past, most notably when ABC News did it with Democrat Kamala Harris this fall. There was no immediate response to a request for comment on Friday. In the piece, Time called into question statements Trump made about border security, autism and the size of a crowd at one of his rallies. When the president-elect talked about the “massive” mandate he had received from voters, Time pointed out that former President Barack Obama won more electoral votes the two times he had run for president. The magazine also questioned Trump’s claim that he would do interviews with anyone who asked during the campaign, if he had the time. The candidate rejected a request to speak the magazine said. “In the final months of his campaign, Trump prioritized interviews with podcasts over mainstream media,” reporters Simmone Shah and Leslie Dickstein wrote.