Pitt’s regular season ended Saturday in Chestnut Hill, Mass., but really in another state of misery. A series of mishaps, penalties and even more injuries led to the Panthers’ losing streak reaching five in a 34-23 Boston College victory. That was after Pitt (7-5, 3-5) started the game without its three most important players on offense: starting quarterback Eli Holstein, running back Desmond Reid and offensive left tackle Branson Taylor, who missed his sixth consecutive game. A day before the opening kickoff, Holstein (leg) was declared out, and his replacement, Nate Yarnell, injured his hand in the first quarter. Yarnell’s injury wasn’t enough to keep him on the bench for more than three snaps, but he was under pressure from the Eagles’ pass rush throughout the game. He had no running game to lean on — 31 net yards made Pitt one-dimensional — and freshman Juelz Goff was the only healthy scholarship back available after Derrick Davis was injured on his fifth carry. Yarnell ended up completing 23 of 42 passes for 296 yards and touchdown passes of 11 and 5 yards to tight end Gavin Bartholomew and 15 yards to Konata Mumpfield, who finished with eight receptions for 144. Hurried 14 times and sacked six, Yarnell was smothered by BC defensive end Neto Okpala late in the second quarter, with the football popping into the air, where 270-pound defensive tackle Tyeus Clemons secured it and ran 55 yards for a touchdown. That gave Boston College (7-5, 4-4) a 20-7 lead that was trimmed to 20-10 when Pitt’s Ben Sauls hit a 57-yard field goal on the last snap of the half. It was Sauls’ fifth field goal of 50 yards or longer in six attempts this season. After intermission, Bartholomew’s second touchdown cut the lead to 20-17, but Boston College immediately punched back. Quarterback Grayson James hit Reed Harris for a 28-yard touchdown and a 27-17 advantage with 2 minutes, 23 seconds left in the third quarter. The final indignity emerged early in the fourth quarter when coach Pat Narduzzi gambled on fourth-and-2 from the Pitt 41. Yarnell fumbled the snap, the Eagles took over on downs and James threw another touchdown pass, 15 yards to Kamari Morales. For the game, James completed 20 of 28 passes for 253 of Boston College’s 386 total yards. Boston College moved to the Pitt 8 on its first possession but could not finish the drive. Pitt middle linebacker Brandon George, who tied Cal Adomitis’ school record for games played (64) the minute he stepped on the field, made the big play, throwing down running back Kye Robichaux for a 1-yard loss on fourth down. In the end, though, it didn’t matter because Jordan McDonald scored on a 36-yard run the next time Boston College got its hands on the ball. The Eagles were forced to settle for a 6-0 lead when the snap on the extra-point try was fumbled. Pitt handled more misfortune in the second quarter when officials ruled a Boston College punt hit Pitt cornerback Ryland Gandy before it was recovered by the Eagles’ Bryant Worrell. Instead of Pitt having good field position at the BC 34, the Eagles retained possession. Pitt’s defense forced another punt, but the field was flipped when Pitt got the ball on its 13. Boston College seized a 13-0 lead before the end of the first half when Robichaux bulled his way into the end zone for a 2-yard score. The touchdown was set up when James hit Harris for a 53-yard completion.
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A 21-year-old Goderich man is facing more than 20 criminal charges related to sex crimes involving minors, and police believe there may be more victims. The police investigation started Oct. 25 after reports from what police described as, "A series of victims in the Huron County area." Cole Wheeler has been arrested and charged. He is still in custody and is scheduled to appear in court at a later date. Charges laid Anyone with information is asked to contact the Huron County OPP at 1-888-310-1122 or (519) 482-1677. If you wish to remain anonymous, you may call Crime Stoppers at 1-800-222-TIPS (8477) or submit a web tip. London Top Stories One person dead after two-vehicle crash involving delivery truck Budget Day 1: Council holds the line on 7.4% tax rate increase but funds shelter beds and more park maintenance London man arrested after attempting to break into a home, threatening residents Goderich man charged with sex crimes and luring a child 'We asked.. 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ABU DHABI — At the 2024 Technovation event in the United Arab Emirates' capital, Philip Morris International (PMI) reaffirmed its commitment to a smoke-free future, showcasing the company's progress and ongoing efforts to transition adult smokers to science-based alternatives. PMI remains optimistic about meeting its ambitious 2030 smoke-free target, with over two-thirds of its revenue expected to come from smoke-free products. According to the company, they are committed to replacing every cigarette for adults who would otherwise continue smoking with smoke-free alternatives, aiming to reduce the global toll of smoking-related diseases, which claim approximately 8 million lives annually. Register to read this story and more for free . Signing up for an account helps us improve your browsing experience. OR See our subscription options.The injunction, which the Court said it will enter in January 2025 , is expected to prohibit Bruker from making, using, selling or offering to sell in the United States its GeoMx Digital Spatial Profiler and associated instruments, reagents and services for RNA and protein detection. At the request of 10x Genomics, the injunction will not block ongoing research by researchers who installed a GeoMx instrument prior to November 18, 2023 . Such customers can continue to purchase GeoMx reagents for use with existing GeoMx instruments for purposes of continuing their ongoing research. The Court found that making such an exception for ongoing research strikes a "workable balance between protecting the patentee's rights and protecting the public from the injunction's adverse effects." In addition, the Court affirmed the $31 million damages awarded by the November 2023 jury verdict, as well as supplemental damages and interest that will be added to the total damages when final judgment is entered. "Today's decision helps to safeguard our decade-long investment in innovation and ensures we can continue to develop groundbreaking technologies that help our customers revolutionize science," said Eric Whitaker , Chief Legal Officer at 10x Genomics. "10x exists to fuel scientific progress – not stifle it – and that is why we've done our utmost to ensure this injunction was structured to protect both our intellectual property and existing GeoMx customers' ongoing research." The Court recognized the harm NanoString's infringing conduct caused 10x when it wrote in its ruling, "Having been careful not to license its technology, 10x suffers when it proclaims itself as an innovator in spatial genomics but a competitor is using the same innovative, patented technology." Today's Court decision follows a November 2023 jury verdict that found that NanoString's GeoMx products willfully infringed seven patents exclusively licensed to 10x Genomics by Prognosys. During the trial, the jury heard testimony from the sole inventor of the patents, Illumina co-founder Mark Chee , and NanoString CEO Brad Gray and NanoString CSO Joe Beechem. After hearing all of the evidence, the jury determined that all seven patents had been infringed by NanoString, that each patent was valid, that NanoString willfully infringed those patents and that monetary damages were owed to 10x for the infringement of all seven patents. In affirming the jury's finding that NanoString willfully infringed, the Court relied on the evidence showing that NanoString knew or was willfully blind that its acts would cause infringement of 10x's rights. The asserted patents in Case No. 21-cv-653-MFK include (a) U.S. Patent No. 10,472,669; (b) U.S. Patent No. 10,961,566; (c) U.S. Patent No. 10,983,113; (d) U.S. Patent No. 10,996,219; (e) U.S. Patent No. 11,001,878; (f) U.S. Patent No. 11,008,607 and (g) U.S. Patent No. 11,293,917. About 10x Genomics 10x Genomics is a life science technology company building products to accelerate the mastery of biology and advance human health. Our integrated solutions include instruments, consumables and software for single cell and spatial biology, which help academic and translational researchers and biopharmaceutical companies understand biological systems at a resolution and scale that matches the complexity of biology. Our products are behind breakthroughs in oncology, immunology, neuroscience and more, fueling powerful discoveries that are transforming the world's understanding of health and disease. To learn more, visit 10xgenomics.com or connect with us on LinkedIn or X (Twitter) . Forward Looking Statements This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 as contained in Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, which are subject to the "safe harbor" created by those sections. All statements included in this press release, other than statements of historical facts, may be forward-looking statements. Forward-looking statements generally can be identified by the use of forward-looking terminology such as "may," "might," "will," "should," "expect," "plan," "anticipate," "could," "intend," "target," "project," "contemplate," "believe," "see," "estimate," "predict," "potential," "would," "likely," "seek" or "continue" or the negatives of these terms or variations of them or similar terminology, but the absence of these words does not mean that a statement is not forward-looking. These forward-looking statements include statements regarding litigation and remedies as well as possible outcomes of litigation. These forward-looking statements do not reflect that our success will depend on our ability to obtain, maintain and protect our intellectual property rights, intellectual property litigation could be expensive, time-consuming, unsuccessful and could interfere with our ability to develop, manufacture and commercialize our products or technologies, litigation outcomes are unpredictable or there may be changes in our litigation strategy. These statements are based on management's current expectations, forecasts, beliefs, assumptions and information currently available to management. Actual outcomes and results could differ materially from these statements due to a number of factors and such statements should not be relied upon as representing 10x Genomics, Inc.'s views as of any date subsequent to the date of this press release. 10x Genomics, Inc. disclaims any obligation to update any forward-looking statements provided to reflect any change in 10x Genomics' expectations or any change in events, conditions or circumstances on which any such statement is based, except as required by law. The material risks and uncertainties that could affect 10x Genomics, Inc.'s financial and operating results and cause actual results to differ materially from those indicated by the forward-looking statements made in this press release include those discussed under the captions "Risk Factors" and "Management's Discussion and Analysis of Financial Condition and Results of Operations" in the company's most recently-filed 10-K for the fiscal year ended December 31, 2023 and elsewhere in the documents 10x Genomics, Inc. files with the Securities and Exchange Commission from time to time. Disclosure Information 10x Genomics uses filings with the Securities and Exchange Commission, our website ( www.10xgenomics.com ), press releases, public conference calls, public webcasts and our social media accounts as means of disclosing material non-public information and for complying with our disclosure obligations under Regulation FD. Contacts Investors: investors@10xgenomics.com Media: media@10xgenomics.com View original content to download multimedia: https://www.prnewswire.com/news-releases/us-district-court-awards-10x-genomics-permanent-injunction-in-patent-infringement-lawsuit-against-bruker-corporations-geomx-products-302338627.html SOURCE 10x Genomics, Inc.Tess Daly poses with her lookalike daughter Phoebe on a Christmas night outCRKN stock touches 52-week low at $0.71 amid sharp annual decline