Gene editing technology is being widely deployed to generate precise data about disease-causing gene mutations and networks, helping to identify optimal therapeutic targets. These approaches are fueling efforts to develop cell and gene therapies for a growing number of genetic disorders among an estimated 6,000 Mendelian diseases, most of which still lack cures. In this webinar, our expert panelists will discuss recent insights into the relationship between human genetic variation and disease from functional genomic studies. They will share their preferred strategies for improving payload development and delivery in functional genomics studies using gene editing. Key takeaways include: · An understanding of the complexities of therapeutic development including cell and gene engineering and manufacturing challenges. · An introduction to Revvity’s Dharmacon product suite—solutions for targeted editing in almost any cell type including CRISPR knockout, knock-in, and interference.
LONDON — Olivia Hussey, the actor who starred as a teenage Juliet in the 1968 film "Romeo and Juliet," died, her family said on social media Saturday. She was 73. Hussey died Friday "peacefully at home surrounded by her loved ones," a statement posted to her Instagram account said. Hussey was 15 when director Franco Zeffirelli cast her in his adaptation of the William Shakespeare tragedy after spotting her onstage in the play "The Prime of Miss Jean Brodie," which also starred Vanessa Redgrave. "Romeo and Juliet" won two Oscars and Hussey won a Golden Globe for best new actress for her part as Juliet, opposite British actor Leonard Whiting, who was 16 at the time. "Romeo and Juliet" movie director Franco Zeffirelli, left, and actors Olivia Hussey, center, and Leonard Whiting are seen Sept. 25, 1968, in Paris after the Parisian premiere of the film. Decades later Hussey and Whiting brought a lawsuit against Paramount Pictures alleging sexual abuse, sexual harassment and fraud over nude scenes in the film. They alleged they were initially told they would wear flesh-colored undergarments in a bedroom scene, but on the day of the shoot Zeffirelli told the pair they would wear only body makeup and the camera would be positioned in a way that would not show nudity. They alleged they were filmed in the nude without their knowledge. The case was dismissed by a Los Angeles County judge in 2023, who found their depiction could not be considered child pornography and the pair filed their claim too late. Leonard Whiting, left, and Olivia Hussey arrive April 26, 2018, at the screening of "The Producers" at the 2018 TCM Classic Film Festival Opening Night at the TCL Chinese Theatre in Los Angeles. Whiting was among those who paid tribute to Hussey on Saturday. "Rest now my beautiful Juliet no injustices can hurt you now," he wrote. "And the world will remember your beauty inside and out forever." Hussey was born April 17, 1951, in Bueno Aires, Argentina, and moved to London as a child. She studied at the Italia Conti Academy drama school. She also starred as Mary, the mother of Jesus, in the 1977 television series "Jesus of Nazareth," as well as the 1978 adaptation of Agatha Christie's "Death on the Nile" and horror movies "Black Christmas" and "Psycho IV: The Beginning." She is survived by her husband, David Glen Eisley, her three children and a grandson. Germany players celebrate after Andreas Brehme, left on ground, scores the winning goal in the World Cup soccer final match against Argentina, in the Olympic Stadium, in Rome, July 8, 1990. Andreas Brehme, who scored the only goal as West Germany beat Argentina to win the 1990 World Cup final, died Feb. 20, 2024. He was 63. Brian Mulroney, the former prime minister of Canada, listens during a Senate Foreign Relations Committee hearing on the Canada-U.S.-Mexico relationship, Tuesday, Jan. 30, 2018, on Capitol Hill in Washington. Mulroney died at the age of 84 on Feb. 29, 2024. The Rev. James Lawson Jr. speaks Sept. 17, 2015, in Murfreesboro, Tenn. Lawson Jr., an apostle of nonviolent protest who schooled activists to withstand brutal reactions from white authorities as the Civil Rights Movement gained traction, has died, his family said Monday. He was 95. His family said Lawson died on Sunday after a short illness in Los Angeles, where he spent decades working as a pastor, labor movement organizer and university professor. Lawson was a close adviser to the Rev. Martin Luther King Jr., who called him “the leading theorist and strategist of nonviolence in the world.” Lawson met King in 1957, after spending three years in India soaking up knowledge about Mohandas K. Gandhi’s independence movement. King would travel to India himself two years later, but at the time, he had only read about Gandhi in books. Basketball Hall of Fame inductee Jerry West, representing the 1960 USA Olympic Team, is seen Aug. 13, 2010, during the enshrinement news conference at the Hall of Fame Museum in Springfield, Mass. Jerry West, who was selected to the Basketball Hall of Fame three times in a storied career as a player and executive, and whose silhouette is considered to be the basis of the NBA logo, died June 12, the Los Angeles Clippers announced. He was 86. West, nicknamed “Mr. Clutch” for his late-game exploits as a player, was an NBA champion who went into the Hall of Fame as a player in 1980 and again as a member of the gold medal-winning 1960 U.S. Olympic Team in 2010. He will be enshrined for a third time later this year as a contributor, and NBA Commissioner Adam Silver called West “one of the greatest executives in sports history.” Actor and director Ron Simons, seen Jan. 23, 2011, during the 2011 Sundance Film Festival, died June 12. Simons turned into a formidable screen and stage producer, winning four Tony Awards and having several films selected at the Sundance Film Festival. He won Tonys for producing “Porgy and Bess,” “A Gentleman’s Guide to Love and Murder,” “Vanya and Sonia and Masha and Spike,” and “Jitney.” He also co-produced “Hughie,” with Forest Whitaker, “The Gin Game,” starring Cicely Tyson and James Earl Jones, “Ain’t Too Proud: The Life and Times of The Temptations,” an all-Black production of “A Streetcar Named Desire,” the revival of "for colored girls who have considered suicide/when the rainbow is enuf" and the original work “Thoughts of a Colored Man.” He was in the films “27 Dresses” and “Mystery Team,” as well as on the small screen in “The Resident,” “Law & Order,” “Law & Order: Criminal Intent” and “Law & Order: SVU.” Bob Schul of West Milton, Ohio, hits the tape Oct. 18, 1964, to win the 5,000 meter run at the Olympic Games in Tokyo. Schul, the only American distance runner to win the 5,000 meters at the Olympics, died June 16. He was 86. His death was announced by Miami University in Ohio , where Schul shined on the track and was inducted into the school’s hall of fame in 1973. Schul predicted gold leading into the 1964 Tokyo Olympics and followed through with his promise. On a rainy day in Japan, he finished the final lap in a blistering 54.8 seconds to sprint to the win. His white shorts were covered in mud at the finish. He was inducted into the USA Track and Field Hall of Fame in 1991. He also helped write a book called “In the Long Run.” San Francisco Giants superstar Willie Mays poses for a photo during baseball spring training in 1972. Mays, the electrifying “Say Hey Kid” whose singular combination of talent, drive and exuberance made him one of baseball’s greatest and most beloved players, died June 18. He was 93. The center fielder, who began his professional career in the Negro Leagues in 1948, had been baseball’s oldest living Hall of Famer. He was voted into the Hall in 1979, his first year of eligibility, and in 1999 followed only Babe Ruth on The Sporting News’ list of the game’s top stars. The Giants retired his uniform number, 24, and set their AT&T Park in San Francisco on Willie Mays Plaza. Mays died two days before a game between the Giants and St. Louis Cardinals to honor the Negro Leagues at Rickwood Field in Birmingham , Alabama. Over 23 major league seasons, virtually all with the New York/San Francisco Giants but also including one in the Negro Leagues, Mays batted .301, hit 660 home runs, totaled 3,293 hits, scored more than 2,000 runs and won 12 Gold Gloves. He was Rookie of the Year in 1951, twice was named the Most Valuable Player and finished in the top 10 for the MVP 10 other times. His lightning sprint and over-the-shoulder grab of an apparent extra base hit in the 1954 World Series remains the most celebrated defensive play in baseball history. For millions in the 1950s and ’60s and after, the smiling ballplayer with the friendly, high-pitched voice was a signature athlete and showman during an era when baseball was still the signature pastime. Awarded the Medal of Freedom by President Barack Obama in 2015, Mays left his fans with countless memories. But a single feat served to capture his magic — one so untoppable it was simply called “The Catch.” Actor Donald Sutherland appears Oct. 13, 2017, at the Academy of Motion Picture Arts and Sciences in Beverly Hills, Calif. Sutherland, the Canadian actor whose wry, arrestingly off-kilter screen presence spanned more than half a century of films from “M.A.S.H.” to “The Hunger Games,” died June 20. He was 88. Kiefer Sutherland said on X he believed his father was one of the most important actors in the history of film: “Never daunted by a role, good, bad or ugly. He loved what he did and did what he loved, and one can never ask for more than that.” The tall and gaunt Sutherland, who flashed a grin that could be sweet or diabolical, was known for offbeat characters like Hawkeye Pierce in Robert Altman's "M.A.S.H.," the hippie tank commander in "Kelly's Heroes" and the stoned professor in "Animal House." Before transitioning into a long career as a respected character actor, Sutherland epitomized the unpredictable, antiestablishment cinema of the 1970s. He never stopped working, appearing in nearly 200 films and series. Over the decades, Sutherland showed his range in more buttoned-down — but still eccentric — roles in Robert Redford's "Ordinary People" and Oliver Stone's "JFK." More, recently, he starred in the “Hunger Games” films. A memoir, “Made Up, But Still True,” is due out in November. Actor Bill Cobbs, a cast member in "Get Low," arrives July 27, 2010, at the premiere of the film in Beverly Hills, Calif. Cobbs, the veteran character actor who became a ubiquitous and sage screen presence as an older man, died June 25. He was 90. A Cleveland native, Cobbs acted in such films as “The Hudsucker Proxy,” “The Bodyguard” and “Night at the Museum.” He made his first big-screen appearance in a fleeting role in 1974's “The Taking of Pelham One Two Three." He became a lifelong actor with some 200 film and TV credits. The lion share of those came in his 50s, 60s, and 70s, as filmmakers and TV producers turned to him again and again to imbue small but pivotal parts with a wizened and worn soulfulness. Cobbs appeared on television shows including “The Sopranos," “The West Wing,” “Sesame Street” and “Good Times.” He was Whitney Houston's manager in “The Bodyguard” (1992), the mystical clock man of the Coen brothers' “The Hudsucker Proxy” (1994) and the doctor of John Sayles' “Sunshine State” (2002). He played the coach in “Air Bud” (1997), the security guard in “Night at the Museum” (2006) and the father on “The Gregory Hines Show." Cobbs rarely got the kinds of major parts that stand out and win awards. Instead, Cobbs was a familiar and memorable everyman who left an impression on audiences, regardless of screen time. He won a Daytime Emmy Award for outstanding limited performance in a daytime program for the series “Dino Dana” in 2020. Independent gubernatorial candidate Kinky Friedman speaks with the media Nov. 7, 2009, at his campaign headquarters in Austin, Texas. The singer, songwriter, satirist and novelist, who led the alt-country band Texas Jewboys, toured with Bob Dylan, sang with Willie Nelson, and dabbled in politics with campaigns for Texas governor and other statewide offices, died June 27. He was 79 and had suffered from Parkinson's disease. Often called “The Kinkster" and sporting sideburns, a thick mustache and cowboy hat, Friedman earned a cult following and reputation as a provocateur throughout his career across musical and literary genres. In the 1970s, his satirical country band Kinky Friedman and the Texas Jewboys wrote songs with titles such as “They Ain't Makin' Jews Like Jesus Anymore” and “Get Your Biscuits in the Oven and Your Buns in Bed.” Friedman joined part of Bob Dylan's Rolling Thunder Revue tour in 1976. By the 1980s, Friedman was writing crime novels that often included a version of himself, and he wrote a column for Texas Monthly magazine in the 2000s. Friedman's run at politics brought his brand of irreverence to the serious world of public policy. In 2006, Friedman ran for governor as an independent in a five-way race that included incumbent Republican Rick Perry. Friedman launched his campaign against the backdrop of the Alamo. Martin Mull participates in "The Cool Kids" panel during the Fox Television Critics Association Summer Press Tour on Aug. 2, 2018, at The Beverly Hilton hotel in Beverly Hills, Calif. Mull, whose droll, esoteric comedy and acting made him a hip sensation in the 1970s and later a beloved guest star on sitcoms including “Roseanne” and “Arrested Development,” died June 28. He was 80. Mull, who was also a guitarist and painter, came to national fame with a recurring role on the Norman Lear-created satirical soap opera “Mary Hartman, Mary Hartman,” and the starring role in its spinoff, “Fernwood Tonight." His first foray into show business was as a songwriter, penning the 1970 semi-hit “A Girl Named Johnny Cash” for singer Jane Morgan. He would combine music and comedy in an act that he brought to hip Hollywood clubs in the 1970s. Mull often played slightly sleazy, somewhat slimy and often smarmy characters as he did as Teri Garr's boss and Michael Keaton's foe in 1983's “Mr. Mom.” He played Colonel Mustard in the 1985 movie adaptation of the board game “Clue,” which, like many things Mull appeared in, has become a cult classic. The 1980s also brought what many thought was his best work, “A History of White People in America,” a mockumentary that first aired on Cinemax. Mull co-created the show and starred as a “60 Minutes” style investigative reporter investigating all things milquetoast and mundane. Willard was again a co-star. In the 1990s he was best known for his recurring role on several seasons on “Roseanne,” in which he played a warmer, less sleazy boss to the title character, an openly gay man whose partner was played by Willard, who died in 2020 . Mull would later play private eye Gene Parmesan on “Arrested Development,” a cult-classic character on a cult-classic show, and would be nominated for an Emmy, his first, in 2016 for a guest run on “Veep.” Screenwriter Robert Towne poses at The Regency Hotel, March 7, 2006, in New York. Towne, the Oscar-winning screenplay writer of "Shampoo," "The Last Detail" and other acclaimed films whose work on "Chinatown" became a model of the art form and helped define the jaded allure of his native Los Angeles, died Monday, July 1, 2024, surrounded by family at his home in Los Angeles, said publicist Carri McClure. She declined to comment on any cause of death. Vic Seixas of the United States backhands a volley from Denmark's Jurgen Ulrich in the first round of men's singles match at Wimbledon, England, June 27, 1967. Vic Seixas, a Wimbledon winner and tennis Hall of Famer who was the oldest living Grand Slam champion, has died July 5 at the age of 100. The International Tennis Hall of Fame announced Seixas’ death on Saturday July 6, 2024, based on confirmation from his daughter Tori. In this June 30, 2020, file photo, Sen. James Inhofe, R-Okla., speaks to reporters following a GOP policy meeting on Capitol Hill in Washington. Former Sen. Jim Inhofe of Oklahoma died July 9. He was 89. The family says in a statement that the Republican had a stroke during the July Fourth holiday and died Tuesday morning. Inhofe was a powerful fixture in state politics for decades. He doubted that climate change was caused by human activity, calling the theory “the greatest hoax ever perpetrated on the American people.” As Oklahoma’s senior U.S. senator, he was a staunch supporter of the state’s military installations. He was elected to a fifth Senate term in 2020 and stepped down in early 2023. The Oak Ridge Boys, from left, Joe Bonsall, Richard Sterban, Duane Allen and William Lee Golden hold their awards for Top Vocal Group and Best Album of the Year for "Ya'll Come Back Saloon", during the 14th Annual Academy of Country Music Awards in Los Angeles, Calif., May 3, 1979. Bonsall died on July 9, 2024, from complications of Amyotrophic Lateral Sclerosis in Hendersonville, Tenn. He was 76. A Philadelphia native and resident of Hendersonville, Tennessee, Bonsall joined the Oak Ridge Boys in 1973, which originally formed in the 1940s. He saw the band through its golden period in the '80s and beyond, which included their signature 1981 song “Elvira.” The hit marked a massive crossover moment for the group, reaching No. 1 on the country chart and No. 5 on Billboard’s all-genre Hot 100. The group is also known for such hits as 1982’s “Bobbie Sue." Shelley Duvall poses for photographers at the 30th Cannes Film Festival in France, May 27, 1977. Duvall, whose wide-eyed, winsome presence was a mainstay in the films of Robert Altman and who co-starred in Stanley Kubrick's “The Shining,” died July 11. She was 75. Dr. Ruth Westheimer holds a copy of her book "Sex for Dummies" at the International Frankfurt Book Fair 'Frankfurter Buchmesse' in Frankfurt, Germany, Thursday, Oct. 11, 2007. Westheimer, the sex therapist who became a pop icon, media star and best-selling author through her frank talk about once-taboo bedroom topics, died on July 12, 2024. She was 96. Richard Simmons sits for a portrait in Los Angeles, June 23, 1982. Simmons, a fitness guru who urged the overweight to exercise and eat better, died July 13 at the age of 76. Simmons was a court jester of physical fitness who built a mini-empire in his trademark tank tops and short shorts by urging the overweight to exercise and eat better. Simmons was a former 268-pound teen who shared his hard-won weight loss tips as the host of the Emmy-winning daytime “Richard Simmons Show" and the “Sweatin' to the Oldies” line of exercise videos, which became a cultural phenomenon. Former NFL receiver Jacoby Jones died July 14 at age 40. Jones' 108-yard kickoff return in 2013 remains the longest touchdown in Super Bowl history. The Houston Texans were Jones’ team for the first five seasons of his career. They announced his death on Sunday. In a statement released by the NFL Players Association, his family said he died at his home in New Orleans. A cause of death was not given. Jones played from 2007-15 for the Texans, Baltimore Ravens, San Diego Chargers and Pittsburgh Steelers. He made several huge plays for the Ravens during their most recent Super Bowl title season, including that kick return. The "Beverly Hills, 90210" star whose life and career were roiled by tabloid stories, Shannen Doherty died July 13 at 53. Doherty's publicist said the actor died Saturday following years with breast cancer. Catapulted to fame as Brenda in “Beverly Hills, 90210,” she worked in big-screen films including "Mallrats" and "Jay and Silent Bob Strike Back" and in TV movies including "A Burning Passion: The Margaret Mitchell Story," in which she played the "Gone with the Wind" author. Doherty co-starred with Holly Marie Combs and Alyssa Milano in the series “Charmed” from 1998-2001; appeared in the “90210” sequel series seven years later and competed on “Dancing with the Stars” in 2010. Actor James Sikking poses for a photograph at the Los Angeles gala celebrating the 20th anniversary of the National Organization for Women, Dec. 1, 1986. Sikking, who starred as a hardened police lieutenant on “Hill Street Blues” and as the titular character's kindhearted dad on “Doogie Howser, M.D.,” died July 13 of complications from dementia, his publicist Cynthia Snyder said in a statement. He was 90. Pat Williams chats with media before the 2004 NBA draft in Orlando, Fla. Williams, a co-founder of the Orlando Magic and someone who spent more than a half-century working within the NBA, died July 17 from complications related to viral pneumonia. The team announced the death Wednesday. Williams was 84. He started his NBA career as business manager of the Philadelphia 76ers in 1968, then had stints as general manager of the Chicago Bulls, the Atlanta Hawks and the 76ers — helping that franchise win a title in 1983. Williams was later involved in starting the process of bringing an NBA team to Orlando. The league’s board of governors granted an expansion franchise in 1987, and the team began play in 1989. Lou Dobbs speaks Feb. 24, 2017, at the Conservative Political Action Conference in Oxon Hill, Md. Dobbs, the conservative political pundit and veteran cable TV host who was a founding anchor for CNN and later was a nightly presence on Fox Business Network for more than a decade, died July 18. He was 78. His death was announced in a post on his official X account, which called him a “fighter till the very end – fighting for what mattered to him the most, God, his family and the country.” He hosted “Lou Dobbs Tonight” on Fox from 2011 to 2021, following two separate stints at CNN. No cause of death was given. Bob Newhart, center, poses with members of the cast and crew of the "Bob Newhart Show," from top left, Marcia Wallace, Bill Daily, Jack Riley, and, Suzanne Pleshette, foreground left, and Dick Martin at TV Land's 35th anniversary tribute to "The Bob Newhart Show" on Sept. 5, 2007, in Beverly Hills, Calif. Newhart has died at age 94. Jerry Digney, Newhart’s publicist, says the actor died July 18 in Los Angeles after a series of short illnesses. The accountant-turned-comedian gained fame with a smash album and became one of the most popular TV stars of his time. Newhart was a Chicago psychologist in “The Bob Newhart Show” in the 1970s and a Vermont innkeeper on “Newhart” in the 1980s. Both shows featured a low-key Newhart surrounded by eccentric characters. The second had a twist ending in its final show — the whole series was revealed to have been a dream by the psychologist he played in the other show. Cheng Pei-pei, a Chinese-born martial arts film actor who starred in Ang Lee’s “Crouching Tiger, Hidden Dragon,” died July 17 at age 78. Her family says Cheng, who had been diagnosed with a rare illness with symptoms similar to Parkinson’s disease, passed away Wednesday at home surrounded by her loved ones. The Shanghai-born film star became a household name in Hong Kong, once dubbed the Hollywood of the Far East, for her performances in martial arts movies in the 1960s. She played Jade Fox, who uses poisoned needles, in “Crouching Tiger, Hidden Dragon,” which was released in 2000, grossed $128 million in North America and won four Oscars. Abdul “Duke” Fakir holds his life time achievement award backstage at the 51st Annual Grammy Awards on Feb. 8, 2009, in Los Angeles. The last surviving original member of the Four Tops died July 22. Abdul “Duke” Fakir was 88. He was a charter member of the Motown group along with lead singer Levi Stubbs, Renaldo “Obie" Benson and Lawrence Payton. Between 1964 and 1967, the Tops had 11 top 20 hits and two No. 1′s: “I Can’t Help Myself (Sugar Pie Honey Bunch)” and the operatic classic “Reach Out I’ll Be There.” Other songs, often stories of romantic pain and longing, included “Baby I Need Your Loving,” “Standing in the Shadows of Love,” “Bernadette” and “Just Ask the Lonely.” Sculptress Elizabeth Catlett, left, then-Washington D.C. Mayor Sharon Pratt Dixon, center, and then-curator, division of community life, Smithsonian institution Bernice Johnson Reagon chat during the reception at the Candace awards on June 25, 1991 in New York. Reagon, a musician and scholar who used her rich, powerful contralto voice in the service of the American Civil Rights Movement and human rights struggles around the world, died on July 16, 2024, according to her daughter's social media post. She was 81. John Mayall, the British blues musician whose influential band the Bluesbreakers was a training ground for Eric Clapton, Mick Fleetwood and many other superstars, died July 22. He was 90. He is credited with helping develop the English take on urban, Chicago-style rhythm and blues that played an important role in the blues revival of the late 1960s. A statement on Mayall's official Instagram page says he died Monday at his home in California. Though Mayall never approached the fame of some of his illustrious alumni, he was still performing in his late 80s, pounding out his version of Chicago blues. Erica Ash, an actor and comedian skilled in sketch comedy who starred in the parody series “Mad TV” and “Real Husbands of Hollywood,” has died. She was 46. Her publicist and a statement by her mother, Diann, says Ash died July 28 in Los Angeles of cancer. Ash impersonated Michelle Obama and Condoleeza Rice on “Mad TV,” a Fox sketch series, and was a key performer on the Rosie O’Donnell-created series “The Big Gay Sketch Show.” Her other credits included “Scary Movie V,” “Uncle Drew” and the LeBron James-produced basketball dramedy “Survivor’s Remorse.” On the BET series “Real Husbands of Hollywood,” Ash played the ex-wife of Kevin Hart’s character. Jack Russell, the lead singer of the bluesy '80s metal band Great White whose hits included “Once Bitten Twice Shy” and “Rock Me” and was fronting his band the night 100 people died in a 2003 nightclub fire in Rhode Island, died Wednesday, Aug. 7, 2024. He was 63. Juan “Chi Chi” Rodriguez, a Hall of Fame golfer whose antics on the greens and inspiring life story made him among the sport’s most popular players during a long professional career, died Thursday, Aug. 8, 2024. Susan Wojcicki, the former YouTube chief executive officer and longtime Google executive, died Friday, Aug. 9, 2024, after suffering with non small cell lung cancer for the past two years. She was 56. Frank Selvy, an All-America guard at Furman who scored an NCAA Division I-record 100 points in a game and later played nine NBA seasons, died Tuesday, Aug. 13, 2024. He was 91. Wallace “Wally” Amos, the creator of the cookie empire that took his name and made it famous and who went on to become a children’s literacy advocate, died Tuesday, Aug. 13, 2024, from complications with dementia. He was 88. Gena Rowlands, hailed as one of the greatest actors to ever practice the craft and a guiding light in independent cinema as a star in groundbreaking movies by her director husband, John Cassavetes, and who later charmed audiences in her son's tear-jerker “The Notebook,” died Wednesday, Aug. 14, 2024. She was 94. Peter Marshall, the actor and singer turned game show host who played straight man to the stars for 16 years on “The Hollywood Squares,” died. Thursday, Aug. 15, 2024 He was 98. Alain Delon, the internationally acclaimed French actor who embodied both the bad guy and the policeman and made hearts throb around the world, died Sunday, Aug. 18, 2024. He was 88. Phil Donahue, whose pioneering daytime talk show launched an indelible television genre that brought success to Oprah Winfrey, Montel Williams, Ellen DeGeneres and many others, died Sunday, Aug. 18, 2024, after a long illness. He was 88. Al Attles, a Hall of Famer who coached the 1975 NBA champion Warriors and spent more than six decades with the organization as a player, general manager and most recently team ambassador, died Tuesday, Aug. 20, 2024. He was 87. John Amos, who starred as the family patriarch on the hit 1970s sitcom “Good Times” and earned an Emmy nomination for his role in the seminal 1977 miniseries “Roots,” died Wednesday, Aug. 21, 2024. He was 84. James Darren, a teen idol who helped ignite the 1960s surfing craze as a charismatic beach boy paired off with Sandra Dee in the hit film “Gidget,” died Monday, Sept. 2, 2024. He was 88. James Earl Jones, who overcame racial prejudice and a severe stutter to become a celebrated icon of stage and screen has died. He was 93. His agent, Barry McPherson, confirmed Jones died Sept. 9 at home. Jones was a pioneering actor who eventually lent his deep, commanding voice to CNN, “The Lion King” and Darth Vader. Working deep into his 80s, he won two Emmys, a Golden Globe, two Tony Awards, a Grammy, the National Medal of Arts, the Kennedy Center Honors and was given an honorary Oscar and a special Tony for lifetime achievement. In 2022, a Broadway theater was renamed in his honor. Frankie Beverly, who with his band Maze inspired generations of fans with his smooth, soulful voice and lasting anthems including “Before I Let Go,” has died. He was 77. His family said in a post on the band’s website and social media accounts that Beverly died Sept. 10. In the post, which asked for privacy, the family said “he lived his life with a pure soul, as one would say, and for us, no one did it better.” The post did not say his cause of death or where he died. Beverly, whose songs include “Joy and Pain,” “Love is the Key,” and “Southern Girl,” finished his farewell “I Wanna Thank You Tour” in his hometown of Philadelphia in July. Joe Schmidt, the Hall of Fame linebacker who helped the Detroit Lions win NFL championships in 1953 and 1957 and later coached the team, has died. He was 92. The Lions said family informed the team Schmidt died Sept. 11. A cause of death was not provided. One of pro football’s first great middle linebackers, Schmidt played his entire NFL career with the Lions from 1953-65. An eight-time All-Pro, he was enshrined into the Pro Football Hall of Fame in 1973 and the college football version in 2000. Born in Pittsburgh, Schmidt played college football in his hometown at Pitt. Chad McQueen, an actor known for his performances in the “Karate Kid” movies and the son of the late actor and racer Steve McQueen, died Sep. 11. His lawyer confirmed his death at age 63. McQueen's family shared a statement on social media saying he lived a life “filled with love and dedication.” McQueen was a professional race car driver, like his father, and competed in the famed 24 Hours of Le Mans and the 24 Hours of Daytona races. He is survived by his wife Jeanie and three children, Chase, Madison and Steven, who is an actor best known for “The Vampire Diaries.” Tito Jackson, one of the brothers who made up the beloved pop group the Jackson 5, died at age 70 on Sept. 15. Jackson was the third of nine children, including global superstars Michael and Janet. The Jackson 5 included brothers Jackie, Tito, Jermaine, Marlon and Michael. They signed with Berry Gordy’s Motown empire in the 1960s. The group was inducted into the Rock & Roll Hall of Fame in 1997 and produced several No. 1 hits in the 1970s, including “ABC,” “I Want You Back” and “I’ll Be There.” John David “JD” Souther has died. He was a prolific songwriter and musician whose collaborations with the Eagles and Linda Ronstadt helped shape the country-rock sound that took root in Southern California in the 1970s. Souther joined in on some of the Eagles’ biggest hits, such as “Best of My Love,” “New Kid in Town,” and “Heartache Tonight." The Songwriters Hall of Fame inductee also collaborated with James Taylor, Bob Seger, Bonnie Raitt and many more. His biggest hit as a solo artist was “You’re Only Lonely.” He was about to tour with Karla Bonoff. Souther died Sept. 17 at his home in New Mexico, at 78. In this photo, JD Souther and Alison Krauss attend the Songwriters Hall of Fame 44th annual induction and awards gala on Thursday, June 13, 2013 in New York. Sen. Dan Evans stands with his three sons, from left, Mark, Bruce and Dan Jr., after he won the election for Washington's senate seat in Seattle, Nov. 8, 1983. Evans, a former Washington state governor and a U.S. Senator, died Sept. 20. The popular Republican was 98. He served as governor from 1965 to 1977, and he was the keynote speaker at the 1968 National Republican Convention. In 1983, Evans was appointed to served out the term of Democratic Sen. Henry “Scoop” Jackson after he died in office. Evans opted not to stand for election in 1988, citing the “tediousness" of the Senate. He later served as a regent at the University of Washington, where the Daniel J. Evans School of Public Policy and Governance bears his name. Eugene “Mercury” Morris, who starred for the unbeaten 1972 Miami Dolphins as part of a star-studded backfield and helped the team win two Super Bowl titles, died Sept. 21. He was 77. The team on Sunday confirmed the death of Morris, a three-time Pro Bowl selection. In a statement, his family said his “talent and passion left an indelible mark on the sport.” Morris was the starting halfback and one of three go-to runners that Dolphins coach Don Shula utilized in Miami’s back-to-back title seasons of 1972 and 1973, alongside Pro Football Hall of Famer Larry Csonka and Jim Kiick. Morris led the Dolphins in rushing touchdowns in both of those seasons. John Ashton, the veteran character actor who memorably played the gruff but lovable police detective John Taggart in the “Beverly Hills Cop” films, died Thursday, Sept. 26, 2024. He was 76. Maggie Smith, who won an Oscar for 1969 film “The Prime of Miss Jean Brodie” and won new fans in the 21st century as the dowager Countess of Grantham in “Downton Abbey” and Professor Minerva McGonagall in the Harry Potter films, died Sept. 27 at 89. Smith's publicist announced the news Friday. She was frequently rated the preeminent British female performer of a generation that included Vanessa Redgrave and Judi Dench. “Jean Brodie” brought her the Academy Award for best actress in 1969. Smith added a supporting actress Oscar for “California Suite” in 1978. Kris Kristofferson, a Rhodes scholar with a deft writing style and rough charisma who became a country music superstar and an A-list Hollywood actor, died Saturday, Sept. 28, 2024. He was 88. Drake Hogestyn, the “Days of Our Lives” star who appeared on the show for 38 years, died Saturday, Sept. 28, 2024. He was 70. Ron Ely, the tall, musclebound actor who played the title character in the 1960s NBC series “Tarzan,” died Sunday, Sept. 29, 2024, at age 86. Dikembe Mutombo, a Basketball Hall of Famer who was one of the best defensive players in NBA history and a longtime global ambassador for the game, died Monday, Sept. 30, 2024, from brain cancer, the league announced. He was 58. Frank Fritz, left, part of a two-man team who drove around the U.S. looking for antiques and collectibles to buy and resell on the reality show “American Pickers,” died Monday, Sept. 30, 2024. He was 60. He's shown here with co-host Mike Wolfe at the A+E Networks 2015 Upfront in New York on April 30, 2015. Pete Rose, baseball’s career hits leader and fallen idol who undermined his historic achievements and Hall of Fame dreams by gambling on the game he loved and once embodied, died Monday, Sept. 30, 2024. He was 83. Cissy Houston, the mother of Whitney Houston and a two-time Grammy winner who performed alongside superstar musicians like Elvis Presley and Aretha Franklin, died Monday, Oct. 7, 2024, in her New Jersey home. She was 91. Ethel Kennedy, the wife of Sen. Robert F. Kennedy, who raised their 11 children after he was assassinated and remained dedicated to social causes and the family’s legacy for decades thereafter, died on Thursday, Oct. 10, 2024, her family said. She was 96. Former One Direction singer Liam Payne, 31, whose chart-topping British boy band generated a global following of swooning fans, was found dead Wednesday, Oct. 16, 2024, after falling from a hotel balcony in Buenos Aires, local officials said. He was 31. Mitzi Gaynor, among the last survivors of the so-called golden age of the Hollywood musical, died of natural causes in Los Angeles on Thursday, Oct. 17, 2024. She was 93. Fernando Valenzuela, the Mexican-born phenom for the Los Angeles Dodgers who inspired “Fernandomania” while winning the NL Cy Young Award and Rookie of the Year in 1981, died Tuesday, Oct. 22, 2024. He was 63. Jack Jones, a Grammy-winning crooner known for “The Love Boat” television show theme song, died, Wednesday, Oct. 23, 2024. He was 86. Phil Lesh, a founding member of the Grateful Dead, died Friday, Oct. 25, 2024, at age 84. Teri Garr, the quirky comedy actor who rose from background dancer in Elvis Presley movies to co-star of such favorites as "Young Frankenstein" and "Tootsie," died Tuesday, Oct 29, 2024. She was 79. Quincy Jones, the multitalented music titan whose vast legacy ranged from producing Michael Jackson’s historic “Thriller” album to writing prize-winning film and television scores and collaborating with Frank Sinatra, Ray Charles and hundreds of other recording artists, died Sunday, Nov 3, 2024. He was 91 Bobby Allison, founder of racing’s “Alabama Gang” and a NASCAR Hall of Famer, died Saturday, Nov. 9, 2024. He was 86. Song Jae-lim, a South Korean actor known for his roles in K-dramas “Moon Embracing the Sun” and “Queen Woo,” was found dead at his home in capital Seoul, Tuesday, Nov. 12, 2024. He was 39. British actor Timothy West, who played the classic Shakespeare roles of King Lear and Macbeth and who in recent years along with his wife, Prunella Scales, enchanted millions of people with their boating exploits on Britain's waterways, died Tuesday, Nov 12, 2024. He was 90. Bela Karolyi, the charismatic if polarizing gymnastics coach who turned young women into champions and the United States into an international power in the sport, died Friday, Nov. 15, 2024. He was 82. Arthur Frommer, whose "Europe on 5 Dollars a Day" guidebooks revolutionized leisure travel by convincing average Americans to take budget vacations abroad, died Monday, Nov. 18, 2024. He was 95. Former Chicago Bulls forward Bob Love, a three-time All-Star who spent 11 years in the NBA, died Monday, Nov. 18, 2024. He was 81. Chuck Woolery, the affable, smooth-talking game show host of “Wheel of Fortune,” “Love Connection” and “Scrabble” who later became a right-wing podcaster, skewering liberals and accusing the government of lying about COVID-19, died Saturday, Nov. 23, 2024. He was 83. Barbara Taylor Bradford, a British journalist who became a publishing sensation in her 40s with the saga "A Woman of Substance" and wrote more than a dozen other novels that sold tens of millions of copies, died Sunday, Nov. 24, 2024. She was 91. Hall of Famer Rickey Henderson, the brash speedster who shattered stolen base records and redefined baseball's leadoff position, died Friday, Dec. 20, 2024. He was 65. Greg Gumbel, left, watches as then-Connecticut head coach Jim Calhoun talks to Butler head coach Brad Stevens, right, prior to taping a television interview April 3, 2011, for that year's men's NCAA Final Four college basketball championship game in Houston. Gumbel's family announced Dec. 27 that the longtime CBS sportscaster died from cancer at the age of 78. Sign up to get the most recent local obituaries delivered to your inbox.To our electric vehicle (EV) owners: If you found yourself with the choice to buy another EV or return to an internal combustion engine vehicle (ICEV), which would you do? Well, if you are like most participants in a recent study, you’d replace it with another EV. Those are the results from a Global EV Alliance survey. The international non-profit network of 64 national EV driver’s associations found that 92% of current owners would purchase another EV if given the opportunity. The survey, which reached more than 23,000 EV owners from across 18 different countries, found that only 4% would replace their EV with a plug-in hybrid, and just 1% choose an ICEV. The survey was interesting because it supported a lot of what we’ve been writing about this year at CleanTechnica . Let’s do a deep dive into the survey questions and responses and determine what makes an EV owner so happy with their battery electric transportation. “Lower operating costs:” These include the cost of charging, which is typically cheapest at home (and overnight if one has time-of-use electricity pricing). And if one includes time costs, convenient home charging wins again and provides just more economic rationale for going electric. “The EV is climate friendly:” The electricity system is built for the most demanding hour of the year, but during every other hour there’s excess capacity, and EVs can be programmed to avoid peak hours when the electrical grid is strained. In fact, more and more EV models now can restore electricity to the grid when demand peaks, supporting the grid and preventing blackouts. “The EV is good for the local environment and makes less noise:” Based on where EVs have been sold, driving the average EV in the US produces global warming emissions equal to a hypothetical 94 mile per gallon gasoline car, or less than a third of the emissions of the average new gasoline car. Transportation is the largest sector for emissions, and passenger cars, trucks, and SUVs are the majority of transportation emissions. There is no way to slow down the climate crisis without a fundamental shift from petroleum to clean electricity to power our vehicles. “I am interested in new technology:” Today EVs have ample range (300-400 miles), plentiful remote charging infrastructure along major highway systems, cost one-third to operate compared to gas cars, and no longer require trips to the gas station or service centers for maintenance. Major automotive manufacturers are investing hundreds of billions of dollars to accelerate their EV offerings across all vehicle categories and motor types. “Good driveability:” It’s fascinating to see for oneself EV progress “ in the wild .” It’s even more impressive when you see one on your street or in your neighbor’s driveway! EVs are becoming so common that seeing one is not remarkable any longer. Largely, that’s due to the ease in driving one. “Lower maintenance costs: ” The time has come in which electric vehicle buyers should work in the cost of ownership into their financial planning. The biggest strengths of EVs are their fuel and maintenance costs. Studies indicate that EVs consistently have lower maintenance costs than their ICE alternatives. “EV policies/incentives:” There are many reasons for consumers to buy an EV right now. Buyers will save a bundle on fuel — home charging makes owning an EV reliable and affordable, and road trips in an EV are becoming easier. Electric vehicles have no tailpipe emissions — nearly three quarters of the GHG emissions from a gasoline vehicle come from the tailpipe during vehicle operation, and the planet really can’t take many more internal combustion engines if it is to thrive. Then again, if financial considerations are your main focus, the EV tax credit that is fleetingly available will have real meaning for you. “Competitive sales price:” Prices are falling because of increased competition, lower raw material costs, and more efficient manufacturing. Cox Automotive says a second, significant wave of shoppers is ready to consider buying an electric car in the second half of this decade. “Of all charging 72% is done at home:” Level 1 charging utilizes a regular household 120 volt (V) outlet. This provides around 4 miles of range per hour of charging. Level 2 charging utilizes a 240V outlet, such as one used by an electric dryer. This level of charging provides around 25 miles of range per hour. “13% fast charging:” Faster-charging and less expensive batteries with longer range are helping to push recharging along, with EV battery stakeholders working diligently on exponential improvements. “7% public parking with charging:” Non-Tesla EV owners are keenly aware that learning to charge when on longer road trips is really different than stopping at a Tesla Supercharger. Each time an EV owner charges on the road they become more comfortable with charging platforms and their ins and outs. In this new world of EV charging, there are numerous variables to process: having the charging app loaded on the phone with credit card information; kW max at each station; availability of the stations or their need of repair; if the station can accommodate more than one EV charging at a time; the cost to charge and to hold the account with a minimum balance. “7% work:” While it’s true that the majority of EV charging is done at a combination of homes, shopping sites, and other Level 2 charging stations, many employees also depend on being able to add electrons while they’re at their place of employment. As reported here at CleanTechnica and elsewhere, the nation’s EV charging station network has experienced plenty of bumps along the road to full build-out, and sometimes workplace EV charging stations aren’t as reliable as they should be. If they operate inefficiently, it’s stressful — employees can’t always be confident they’ll be able to charge their cars when they reach their firm. “1% other private:” Automakers are beginning to improve the public charging experience with lounge-like, comfort stations where drivers can relax. As EV charging stations become ubiquitous, competition for which providers offer the best amenities while the charging occurs will become common. Like airport lounges, the executive EV charging station of the future will offer services well beyond electrons. With those options will come differing types of amenities, based on various levels of pricing. “The EV is not sufficient as the only car in the household: ” Effective EV outreach programs prioritize proactively visiting and interacting with rural, low-income, and underserved communities as the first step in removing barriers and making clean transportation accessible to all. “Charging queues:” EV sales are outpacing the growth of chargers, which is causing problems for everyday EV drivers. The US needs to build out its EV charging capacity in order to reach the point where everyone who wants to drive an EV has the electrification to do so — on urban and rural roads, in busy communities and suburbs, in nearly any major intersection where you’d expect to find a gas station. “It requires too much planning:” For local driving, an EV suffices with overnight charging in your garage. You never have to visit a mechanic’s smelly garage for an emissions check. For cross-country driving, though, an EV will only take a little longer for 500 miles a day because much of your charging time is spent during bathroom and meal breaks. However, a 1500-mile trip will definitely take longer in an EV. Naomi Cole and Joe Wachunas nicely summed up the joy in owning an EV on CleanTechnica a few months ago. “Now that we’ve been proud EV owners for seven years, we can’t imagine returning to the loud engines and smoking tailpipes fueling the climate crisis. We won’t even rent a gas car when traveling and have had great luck renting electric vehicles...With EVs you can enjoy the convenience of personal vehicles, save money, and stop emitting pollution from your tailpipe. Win, win, win.” CleanTechnica's Comment Policy LinkedIn WhatsApp Facebook Bluesky Email RedditNone
Harris: Fine Gael ‘will gain seats’ amid further fragmentation of Irish politics
Marin IJ Readers’ Forum for Dec. 29, 2024Georgia quarterback Carson Beck announced Saturday that he will forgo his final year of eligibility and enter the 2025 NFL Draft. Beck, 22, led the Southeastern Conference with 28 touchdown passes and finished third in the SEC with 3,485 passing yards. He also led the conference in interceptions, however. Beck will be a spectator for the Bulldogs in the College Football Playoff after undergoing surgery Monday to repair the ulnar collateral ligament in his right (throwing) elbow. Gunner Stockton is in line to guide No. 2 seed Georgia into the CFP, starting with the Bulldogs' quarterfinal game against No. 7 seed Notre Dame at the Sugar Bowl on Wednesday in New Orleans. "There's unfinished business still this season and I'll be here to support however I can, finish strong!" Beck said in a statement posted on social media. Beck, a fifth-year senior, finished with a 24-3 record in his career with Georgia. "The past five years at the University of Georgia have been nothing short of a dream come true and I will forever cherish the memories that have been made. Thank you Dawg Nation for the time I've been here and to those who've supported and believed in me, thank you," Beck wrote on social media. "It's been an incredible journey and all these moments have ultimately led me to take the next step in my football career. With that being said, I will be declaring for the 2025 NFL Draft. Go Dawgs!" Beck, the Bulldogs' starter all year, was replaced in the second half of the SEC title game with the injury. Stockton helped to guide the Bulldogs to a 22-19 overtime win over Texas and clinch a first-round bye in the first 12-team playoff. --Field Level Media