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BGB-10188 is under clinical development by BeiGene and currently in Phase II for Non-Small Cell Lung Cancer. According to GlobalData, Phase II drugs for Non-Small Cell Lung Cancer have a 38% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval. BGB-10188 overview BeiGene overview BeiGene is a biotechnology company. It specializes in the development and commercialization of immuno-oncology medicines to treat cancers. The company offers Zanubrutinib, a small molecule inhibitor to treat various blood cancers and Sonrotoclax, a small molecule Bcl-2 inhibitor for treating chronic lymphocytic leukemia. BeiGene also provides Tislelizumab (BGB-A317), a monoclonal antibody targeting solid tumors and hematologic cancer; and Pamiparib (BGB-290) against solid tumor malignancies. The company has operations in the US, Australia, Germany, Spain, Canada, Switzerland and Italy. BeiGene is headquartered in the Cayman Islands. For a complete picture of BGB-10188’s drug-specific PTSR and LoA scores, This content was updated on 12 April 2024 From Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors. , the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article. GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s .
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(Bloomberg) — Donald Trump said Canadian Prime Minister Justin Trudeau committed to working to address the border and fentanyl smuggling, key issues that have led the incoming US president to threaten massive tariffs. Trump, in a Truth Social post on Saturday, called their dinner Friday night at his Mar-a-Lago residence in Florida a “very productive meeting” and made no mention of his earlier 25% tariff threat. “I made it very clear that the United States will no longer sit idly by as our citizens become victims to the scourge of this Drug Epidemic, caused mainly by the Drug Cartels, and Fentanyl pouring in from China,” he said. “Prime Minister Trudeau has made a commitment to work with us to end this terrible devastation of US Families.” The dinner included incoming Commerce Secretary and trade czar Howard Lutnick, incoming Interior Secretary Doug Burgum and incoming National Security Advisor Michael Waltz. Trudeau’s delegation included Public Safety Minister Dominic LeBlanc and Chief of Staff Katie Telford. Trump has threatened tariffs on both Canada and Mexico while demanding action on the border. Trudeau, speaking briefly to press as he left his West Palm Beach hotel Saturday, called it “an excellent conversation.” The dinner lasted roughly three hours, with discussion of trade, border security, fentanyl, Ukraine, NATO, Arctic icebreakers, China, pipeline projects and the Middle East, officials with knowledge of the meeting said. They described the meeting as positive. Trump gave no specific indication at the dinner of whether he’d proceed with his tariff plans, one official said. At one point, Trump began choosing a playlist, offering two versions of Leonard Cohen’s Hallelujah — a nod to the Canadian delegation — and playing other songs that were common at his rallies. Trump and Trudeau ate steak and mashed potatoes, while other menu options included meatloaf from a recipe by Mary Trump, the president-elect’s late mother. (Updates with description of dinner starting in seventh paragraph.)