Lizzo Replicates Kendrick Lamar’s Iconic Mustard Shout-Out On Stream With Kai Cenat & SZA
WASHINGTON D.C., DC — Unlike scores of people who scrambled for the blockbuster drugs Ozempic and Wegovy to lose weight in recent years, Danielle Griffin had no trouble getting them. The 38-year-old information technology worker from New Mexico had a prescription. Her pharmacy had the drugs in stock. And her health insurance covered all but $25 to $50 of the monthly cost. For Griffin, the hardest part of using the new drugs wasn’t access . It was finding out that the much-hyped medications didn’t really work for her. “I have been on Wegovy for a year and a half and have only lost 13 pounds,” said Griffin, who watches her diet, drinks plenty of water and exercises regularly. “I’ve done everything right with no success. It’s discouraging.” In clinical trials, most participants taking Wegovy or Mounjaro to treat obesity lost an average of 15% to 22% of their body weight — up to 50 pounds or more in many cases. But roughly 10% to 15% of patients in those trials were “nonresponders” who lost less than 5% of their body weight. Now that millions of people have used the drugs, several obesity experts told The Associated Press that perhaps 20% of patients — as many as 1 in 5 — may not respond well to the medications. It's a little-known consequence of the obesity drug boom, according to doctors who caution eager patients not to expect one-size-fits-all results. “It's all about explaining that different people have different responses,” said Dr. Fatima Cody Stanford, an obesity expert at Massachusetts General Hospital The drugs are known as GLP-1 receptor agonists because they mimic a hormone in the body known as glucagon-like peptide 1. Genetics, hormones and variability in how the brain regulates energy can all influence weight — and a person's response to the drugs, Stanford said. Medical conditions such as sleep apnea can prevent weight loss, as can certain common medications, such as antidepressants, steroids and contraceptives. “This is a disease that stems from the brain,” said Stanford. “The dysfunction may not be the same” from patient to patient. Despite such cautions, patients are often upset when they start getting the weekly injections but the numbers on the scale barely budge. “It can be devastating,” said Dr. Katherine Saunders, an obesity expert at Weill Cornell Medicine and co-founder of the obesity treatment company FlyteHealth. “With such high expectations, there’s so much room for disappointment.” That was the case for Griffin, who has battled obesity since childhood and hoped to shed 70 pounds using Wegovy. The drug helped reduce her appetite and lowered her risk of diabetes, but she saw little change in weight. “It’s an emotional roller coaster,” she said. “You want it to work like it does for everybody else.” The medications are typically prescribed along with eating behavior and lifestyle changes. It’s usually clear within weeks whether someone will respond to the drugs, said Dr. Jody Dushay, an endocrine specialist at Beth Israel Deaconess Medical Center. Weight loss typically begins right away and continues as the dosage increases. For some patients, that just doesn't happen. For others, side effects such as nausea, vomiting and diarrhea force them to halt the medications, Dushay said. In such situations, patients who were counting on the new drugs to pare pounds may think they’re out of options. “I tell them: It's not game over,” Dushay said. Trying a different version of the new class of drugs may help. Griffin, who didn't respond well to Wegovy, has started using Zepbound, which targets an additional hormone pathway in the body. After three months of using the drug, she has lost 7 pounds. “I'm hoping it's slow and steady,” she said. Other people respond well to older drugs, the experts said. Changing diet, exercise, sleep and stress habits can also have profound effects. Figuring out what works typically requires a doctor trained to treat obesity, Saunders noted. “Obesity is such a complex disease that really needs to be treated very comprehensively,” she said. “If what we’re prescribing doesn’t work, we always have a backup plan.” ___ The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group. The AP is solely responsible for all content.
Nearly 1 in 4 Americans report suffering from chronic pain, which can interfere with daily lifeUnderstanding the FDI flow in Hong Kong and ChinaAccording to SI.com , former NBA star Lou Williams has an opinion on who is and should be the face of the WNBA and it’s not Caitlin Clark . Williams thinks that Las Vegas Aces star and WNBA MVP, A’ja Wilson is still the face of the league despite Caitlin Clark’s success in the WNBA. In a recent interview with FanDuel TV show ‘ Run It Back’ , Lou Williams said, “I still think that [the title of face of women’s basketball] still belongs to A’ja Wilson. A’ja has done a tremendous job of being a champion, being an MVP, doing all of these things. And now her visibility has gone up. You’re starting to see her in commercials.... [So] I still feel like it’s A’ja Wilson.” When the discussion arises about who the face of the league is, there are only two logical choices. With A’ja Wilson being the reigning MVP (2020, 2022, and 2024) and Caitlin Clark who was named Time Magazine’s Athlete of the Year 2024 and WNBA Rookie of the Year captivating new WNBA fans, the choices are clear. Wilson has not only won the league MVP in three of the last five seasons, but she has proven to be a team leader in guiding the Aces to two WNBA championships. Last season, Wilson set the single season scoring record with 1,000 points. Clark has brought new fans to the league and a little bit more recognition for the league to people who were not usually watching WNBA games before Clark. You can also measure her superstardom coming into the league from college basketball and playing against the likes of former LSU standout and Chicago Sky star Angel Reese. Williams also went on to say, “A’ja has done a tremendous job of being a champion, being an MVP, doing all of these things. And now her visibility has gone up. You’re starting to see her in commercials.” In respect to Clark, Williams said, “I think some of these people are here for the wrong reasons and I don’t think they stay around to see the tremendous career that she’s gonna put together. Is she the absolute face of the WNBA? She’s one of them, for sure... but I think that still belongs to A’ja Wilson.” This article first appeared on Dice City Sports and was syndicated with permission.
Some 140 years after its first trailblazing luxury train chugged out of Paris’s Gare de l’Est bound for Constantinople, the Orient Express is having something of a rebirth. Arguably the most interesting in a flurry of announcements from the brand is the launch of Orient Express Silenseas, a new collection of yachts that are a collaboration between three French giants: global hospitality group Accor, luxury goods titan LVMH and shipbuilders Chantiers de l’Atlantique. Orient Express Corinthian is the world’s largest sailing yacht. The finished product looks like the lovechild of the fanciest superyacht and the most elegant sailing boat. The first yacht to be completed, Orient Express Corinthian, which at 220m long, with three 100m-high sails, is the world’s largest sailing yacht, won’t be taking paying guests until 2026, but the first images of its interiors have been released. Luxury hotel groups such as Ritz Carlton, Four Seasons and Aman have all announced launches of luxury yachts this year . But while they may be fabulous, they are smallish cruise ships, not yachts. Evrima, for example, the first in the Ritz-Carlton Yacht Collection, offers 224 suites. Then there’s Four Seasons, whose first “yacht”, when it launches in 2026, will have 14 decks and 95 suites. With just 50 cabins, Aman at Sea, which launches in 2027, is the closest of the offerings to a superyacht and also in scale to the 54-suite Orient Express Corinthian. But what Orient Express Corinthian has that none of the others do is sails. The interiors team took inspiration from classic French liners such as SS Normandie. There’s something much cooler and more adventurous-seeming about a great big yacht with sails than an all-bling one with just an engine. This is something that hasn’t escaped Jeff Bezos, who spent $500 million on his three-masted boat Koru , which at 127 metres was the world’s largest sailing yacht – until now. Inspired by the golden age of the French Riviera, Orient Express Corinthian has been designed by French architect and designer Maxime d’Angeac, who has also worked on a new Orient Express train that will launch in France around the same time. The two will combine on certain itineraries. Sustainability was central to the design process, seen through the minimal use of leather, no plastic and lots of walnut wood panelling. “The pillars of Orient Express are art deco, geometric patterns and strong colours, which both train and boat have,” says d’Angeac. “Train interiors can be much darker as this makes them feel cosy and luxurious. The boat [has] much more space and height, so its design feels more Riviera, like a villa on the Côte d’Azur. I’ve also replaced the really small windows you usually get in yacht cabins with huge, durable windows.” Orient Express Corinthian will have five restaurants, eight bars including a speakeasy, two swimming pools including a lap pool, an amphitheatre cabaret space and a private recording studio. In-room spa treatments and meditation sessions will also be available. The boats will spend summers in the Mediterranean and the Adriatic and winters in the Caribbean, with dining, shopping and cultural experiences offered at multiple stop-offs along the way. Sustainability has been at the forefront of the design process, as has working out how to be beautiful but also functional. For example, there is hardly any leather, no plastic and lots of walnut wood panelling, which as well as being elegant and warm is durable and lightweight. The team examined classic French liners such as SS Normandie for inspiration. There are lovely details at every turn: a long, daybed window seat that lifts up to reveal a wooden games box stocked with chess, dominoes and playing cards; luxurious velvet headboards and bathrooms lined in the most decadent-looking Violetta Calacatta marble with crimson walls behind. All of this will be accompanied by Orient Express service, with butlers on hand around the clock. The luxurious bathrooms feature Violetta Calacatta marble. Sustainability was central to the design process, seen through the minimal use of leather, no plastic and lots of walnut wood panellingThe luxurious bathrooms feature Violetta Calacatta marble “The in-room bar,” replies d’Angeac, when I ask him to name a small detail he particularly likes. “When I arrive at a hotel, I’m always excited to see what has been chosen. We are still deciding but I can tell you it will be the best artisan cocktails and chocolate, as opposed to big names. We will simply use small French companies offering the best things.” Silenseas is also debuting groundbreaking wind-harnessing technology that has been 20 years in the making: SolidSail, a rigid, foldable carbon sail and mast system that will provide more than 50 per cent of the yachts’ propulsion. “Wind technology is the future of cruising, everyone knows that,” says d’Angeac. “We can’t just go on producing bigger and bigger boats with enormous polluting engines. Using less gasoline is really important to us, so we will adapt our routes to ensure we follow the wind, which will all be part of the experience.” This hybrid system will combine wind power with an engine running on liquified natural gas (LNG – typically at least 85 per cent methane). While LNG is by no means the perfect option, it is much cleaner than other fossil fuels such as coal, gas or oil, so makes for a better alternative while the infrastructure needed to handle fully renewable energy is still being developed. It was said that Orient Express founder Georges Nagelmackers was first inspired to design a luxury train on a transatlantic crossing to America in 1867, revelling in its luxurious suites, social scene and general grandeur. “I think he would have gone into luxury cruising eventually, had he not died so young,” says d’Agneac. Either way, this feels like a full-circle moment. The Telegraph, LondonPrairie View A&M parts ways with head coach and former Houston Oiler "Bubba" McDowell
Saudi Arabia banned film for 35 years. The Red Sea festival is just one sign of the industry's riseNew Delhi, Nov 24: Chief Minister Omar Abdullah Sunday asked the World Craft Council to help Jammu and Kashmir unlock its craft potential. Speaking at the 60th-anniversary celebrations of the World Craft Council (WCC)’s ‘Craft, Creativity and Compassion’ event in New Delhi, CM Omar said that organisations like WCC could assist J&K in unlocking its full potential in handicrafts and making it sustainable in the years to come. A key highlight of the event was the announcement of the collaboration between the Jammu and Kashmir government and the WCC to establish a World Craft Hub and International Crafts Museum in Srinagar. Emphasising the importance of crafts in preserving cultural identity and giving a fillip to the economic growth, the CM said, “J&K is proud of its rich cultural heritage, deeply rooted in traditional craftsmanship. The handicrafts and handloom sectors, vital pillars of this heritage, hold immense potential for economic growth and social upliftment, particularly in rural areas.” He said that these crafts not only preserve the region’s cultural identity but also provide livelihood for countless artisans. CM Omar expressed hope that as WCC would achieve more milestones to celebrate in years to come, the crafts sector would also emerge stronger in J&K. He expressed hope that the skills and craft knowledge would be transferred to the younger generations. The CM also hosted a dinner for World Craft Council delegates. The event, attended by distinguished national and international delegates, was part of the celebrations to welcome the WCC. During the presentations to the participants, several initiatives undertaken by the J&K government were highlighted including the Wool Processing, Handloom, and Handicrafts Policy-2020, financial assistance programmes, skill development schemes like the Karkhandar initiative, and the promotion of Geographical Indication (GI) certification to protect Kashmiri crafts. It was conveyed that there has been a remarkable increase in exports which have risen from Rs 563 crore in 2021-22 to Rs 1162 crore in 2023-24. The WCC celebrations have been scheduled in two phases from November 21 to 24, which was held in New Delhi and from November 25 to 27 at Srinagar to highlight the significant role of J&K in global crafts. This initiative aims to position Kashmir as a global centre for artisanal excellence to preserve traditional skills and create sustainable revenue streams for artisans. With Srinagar’s recognition as the 63rd World Craft City, the region’s standing as a hub of cultural and artisanal excellence has been further elevated. During the event, a presentation on the crafts of J&K and the way forward, a short film celebrating the global legacy of crafts and Srinagar being designated as a World Craft City was shown to the audience. Besides the CM and delegates from the WCC, the dinner was attended by Advisor to the Chief Minister Nasir Aslam Wani, Chief Secretary Atal Dulloo, Additional Chief Secretary to CM Dheeraj Gupta, Union Additional Secretary in Ministry of Textiles Rohit Kansal, Commissioner Secretary Industries and Commerce Vikramjeet Singh, and Director Handicrafts Kashmir Mehmood Ahmad Shah. From World Craft Council the notable dignitaries present were the President of the WCC Saad Al Qaddumi, Vice President WCC Kevin Murray, Aziz Mutazaev (Uzbekistan), Nadia Meer (South Africa), Aftab Gharda (UK), and delegates from member countries of the WCC, including representatives from Australia, Kuwait, France, the UK, Uzbekistan, South Africa, Ireland, Malaysia, and Turkey, attended the event. Other key officials from the Ministry of Textiles, Government of India, and J&K government and representatives of the craft industry from J&K. The celebrations hold immense significance for J&K, offering global recognition of its artisanal heritage and creating direct and indirect employment opportunities for artisans. By integrating crafts into tourism and connecting local artisans to global markets, the event is expected to have a lasting impact on the region’s cultural and economic landscape. A notable feature of the second leg of the event in Srinagar would be the participation of artisans from Iran and Central Asia, whose visit would help be significant for historical and cultural ties between Central Asian and Kashmiri crafts. The interaction with WCC is expected to foster cross-cultural learning, celebrate shared heritage, and open up avenues for reviving lost techniques. This event is seen as a milestone in J&K’s journey to reclaim its position in the world of crafts. With its artisans at the heart of this revival, collaboration with the WCC is expected to help J&K revive and sustain its rich cultural heritage for generations to come. The event now moves to J&K with the delegates from WCC set to celebrate the 60th anniversary of WCC in Srinagar, starting with their arrival and craft tour on November 25 and a two-day event at the SKICC on November 26 and 27.How an Ontario Amish community became saddled with COVID fines
NEW YORK (AP) — Chuck Woolery, the affable, smooth-talking game show host of “Wheel of Fortune,” “Love Connection” and “Scrabble” who later became a right-wing podcaster, skewering liberals and accusing the government of lying about COVID-19, has died. He was 83. Mark Young, Woolery's podcast co-host and friend, said in an email early Sunday that Woolery died at his home in Texas with his wife, Kristen, present. “Chuck was a dear friend and brother and a tremendous man of faith, life will not be the same without him,” Young wrote. Woolery, with his matinee idol looks, coiffed hair and ease with witty banter, was inducted into the American TV Game Show Hall of Fame in 2007 and earned a daytime Emmy nomination in 1978. In 1983, Woolery began an 11-year run as host of TV’s “Love Connection,” for which he coined the phrase, “We’ll be back in two minutes and two seconds,” a two-fingered signature dubbed the “2 and 2.” In 1984, he hosted TV’s “Scrabble,” simultaneously hosting two game shows on TV until 1990. “Love Connection,” which aired long before the dawn of dating apps, had a premise that featured either a single man or single woman who would watch audition tapes of three potential mates and then pick one for a date. A couple of weeks after the date, the guest would sit with Woolery in front of a studio audience and tell everybody about the date. The audience would vote on the three contestants, and if the audience agreed with the guest’s choice, “Love Connection” would offer to pay for a second date. Woolery told The Philadelphia Inquirer in 2003 that his favorite set of lovebirds was a man aged 91 and a woman aged 87. "She had so much eye makeup on, she looked like a stolen Corvette. He was so old he said, ‘I remember wagon trains.’ The poor guy. She took him on a balloon ride.” Other career highlights included hosting the shows “Lingo," “Greed” and “The Chuck Woolery Show,” as well as hosting the short-lived syndicated revival of “The Dating Game” from 1998 to 2000 and an ill-fated 1991 talk show. In 1992, he played himself in two episodes of TV’s “Melrose Place.” Woolery became the subject of the Game Show Network’s first attempt at a reality show, “Chuck Woolery: Naturally Stoned,” which premiered in 2003. It shared the title of the pop song in 1968 by Woolery and his rock group, the Avant-Garde. It lasted six episode and was panned by critics. Woolery began his TV career at a show that has become a mainstay. Although most associated with Pat Sajak and Vanna White, “Wheel of Fortune” debuted Jan. 6, 1975, on NBC with Woolery welcoming contestants and the audience. Woolery, then 33, was trying to make it in Nashville as a singer. “Wheel of Fortune” started life as “Shopper’s Bazaar,” incorporating Hangman-style puzzles and a roulette wheel. After Woolery appeared on “The Merv Griffin Show” singing “Delta Dawn,” Merv Griffin asked him to host the new show with Susan Stafford. “I had an interview that stretched to 15, 20 minutes,” Woolery told The New York Times in 2003. “After the show, when Merv asked if I wanted to do a game show, I thought, ‘Great, a guy with a bad jacket and an equally bad mustache who doesn’t care what you have to say — that’s the guy I want to be.’” NBC initially passed, but they retooled it as “Wheel of Fortune” and got the green light. After a few years, Woolery demanded a raise to $500,000 a year, or what host Peter Marshall was making on “Hollywood Squares.” Griffin balked and replaced Woolery with weather reporter Pat Sajak. “Both Chuck and Susie did a fine job, and ‘Wheel’ did well enough on NBC, although it never approached the kind of ratings success that ‘Jeopardy!’ achieved in its heyday,” Griffin said in “Merv: Making the Good Life Last,” an autobiography from the 2000s co-written by David Bender. Woolery earned an Emmy nod as host. Born in Ashland, Kentucky, Woolery served in the U.S. Navy before attending college. He played double bass in a folk trio, then formed the psychedelic rock duo The Avant-Garde in 1967 while working as a truck driver to support himself as a musician. The Avant-Garde, which tourbed in a refitted Cadillac hearse, had the Top 40 hit “Naturally Stoned,” with Woolery singing, “When I put my mind on you alone/I can get a good sensation/Feel like I’m naturally stoned.” After The Avant-Garde broke up, Woolery released his debut solo single “I’ve Been Wrong” in 1969 and several more singles with Columbia before transitioning to country music by the 1970s. He released two solo singles, “Forgive My Heart” and “Love Me, Love Me.” Woolery wrote or co-wrote songs for himself and everyone from Pat Boone to Tammy Wynette. On Wynette’s 1971 album “We Sure Can Love Each Other,” Woolery wrote “The Joys of Being a Woman” with lyrics including “See our baby on the swing/Hear her laugh, hear her scream.” After his TV career ended, Woolery went into podcasting. In an interview with The New York Times, he called himself a gun-rights activist and described himself as a conservative libertarian and constitutionalist. He said he hadn’t revealed his politics in liberal Hollywood for fear of retribution. He teamed up with Mark Young in 2014 for the podcast “Blunt Force Truth” and soon became a full supporter of Donald Trump while arguing minorities don’t need civil rights and causing a firestorm by tweeting an antisemitic comment linking Soviet Communists to Judaism. “President Obama’s popularity is a fantasy only held by him and his dwindling legion of juice-box-drinking, anxiety-dog-hugging, safe-space-hiding snowflakes,” he said. Woolery also was active online, retweeting articles from Conservative Brief, insisting Democrats were trying to install a system of Marxism and spreading headlines such as “Impeach him! Devastating photo of Joe Biden leaks.” During the early stages of the pandemic, Woolery initially accused medical professionals and Democrats of lying about the virus in an effort to hurt the economy and Trump’s chances for reelection to the presidency. “The most outrageous lies are the ones about COVID-19. Everyone is lying. The CDC, media, Democrats, our doctors, not all but most, that we are told to trust. I think it’s all about the election and keeping the economy from coming back, which is about the election. I’m sick of it,” Woolery wrote in July 2020. Trump retweeted that post to his 83 million followers. By the end of the month, nearly 4.5 million Americans had been infected with COVID-19 and more than 150,000 had died. Just days later, Woolery changed his stance, announcing his son had contracted COVID-19. “To further clarify and add perspective, COVID-19 is real and it is here. My son tested positive for the virus, and I feel for of those suffering and especially for those who have lost loved ones,” Woolery posted before his account was deleted. Woolery later explained on his podcast that he never called COVID-19 “a hoax” or said “it’s not real,” just that “we’ve been lied to.” Woolery also said it was “an honor to have your president retweet what your thoughts are and think it’s important enough to do that.” In addition to his wife, Woolery is survived by his sons Michael and Sean and his daughter Melissa, Young said. Mark Kennedy is at .`Well-planned conspiracy by UP CM Adityanath, BJP-RSS`: Congress
NoneRuben Amorim is joining a Man Utd in chaos... the mess behind the scenes will make him wish he never left Sporting
Artificial intelligence (AI) is estimated to generate up to $680 billion for the telecommunications industry over the next 15 to 20 years, said John Hoffman, CEO of the Global System for Mobile Communications Association (GSMA) Limited this week. Hoffman was citing a McKinsey report when making the remarks in a speech that he delivered at the opening ceremony of the 2024 World Internet Conference Wuzhen Summit, which is being held in east China’s Zhejiang Province. He said AI is emerging as a powerful force with the potential to transform business and society on an unprecedented scale. About 81 percent of telecom operators around the world are testing generative AI solutions and “Chinese operators are one of the leaders in the space, with big investments, strong government support and a booming tech landscape,” Hoffman said. “China Mobile, China Telecom and China Unicom have already made huge strides in AI research and applications, with solutions that are transforming public services, supply chains and healthcare,” he said. For instance, an intelligent computing service platform has been launched in northwest China to assist local flood control efforts, while an AI database in the country’s southwest is committed to the protection and development of cultural diversity. Across the world, Hoffman said, over 150 million people could have their lives improved by mobile big data and AI solutions in the next five years. Noting that AI brings responsibilities alongside opportunities, Hoffman called for greater attention to the ethical and sustainable development of AI technology. The summit, themed “Embracing a People-centered and AI-for-good Digital Future: Building a Community with a Shared Future in Cyberspace,” will last until Friday.Saudi Arabia Banned Film for 35 Years. the Red Sea Festival Is Just One Sign of the Industry's Rise
First openly trans rep-elect claims GOP spotlighting transgender issues an 'attempt to distract' voters
Analytical Standards Market to Grow by USD 657.8 Million (2024-2028), Report on AI-Powered Market Evolution and Life Science Industry Growth - TechnavioMILWAUKEE (AP) — Jamichael Stillwell had 22 points in Milwaukee's 69-65 win over St. Thomas on Sunday. Stillwell added eight rebounds for the Panthers (5-2). Aaron Franklin had 15 points and eight rebounds. AJ McKee added nine points. Javascript is required for you to be able to read premium content. Please enable it in your browser settings.